Mekhoa ea mofuta
Formethine (matlapa) Tekanyetso: 37
Moetsi: Pharmstandard-Leksredstva (Russia)
Mefuta ea Tsamaiso:
- Tab. 50 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 57
- Tab. 50 mg, li-pcs tse 60., Theko e tsoang ho li-ruble tse 99
Litaelo tsa ho sebelisoa
Formetin ke ntho e sa bitseng chelete e ngata bakeng sa Glucofage, e etselitsoeng ho theola tsoekere e maling. E fumaneha matlapeng a nang le 0.5, 0,85 kapa 1 g ea metformin. E ka baka mathata a tsamaiso ea methapo ea lijo, lekhopho la letlalo, mme haeba ho ka ba le overdose - hypoglycemia le lactic acidosis ka sephetho se bolaeang.
Analogs ea lithethefatsi Foromo
Analogue e theko e phahameng haholo ho tsoa ho li-ruble tse 53.
Moetsi: Merck Sante SAA.S. (Fora)
Mefuta ea Tsamaiso:
- Matlapa a 500 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 110
- Matlapa a 1000 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 185
Litaelo tsa ho sebelisoa
Lithethefatsi tsa Mafora bakeng sa kalafo ea lefu la tsoekere la mofuta oa 2. E rekisitsoe matlapeng a nang le 500 ho isa ho 1000 mg ea metformin e le eona feela motsoako o sebetsang. Ho na le li-contraindication, ka hona, pele ho nka Glucofage, ho bohlokoa ho buisana le setsebi.
Analogue e theko e phahameng haholo ho tsoa ho li-ruble tse 52.
Moetsi: Akrikhin (Russia)
Mefuta ea Tsamaiso:
- Matlapa a 500 mg, li-pcs tse 60., theko ho tsoa li-ruble tse 109
- Letlapa 850 mg, li-pcs tse 60., Theko e tsoang ho li-ruble tse 190
Litaelo tsa ho sebelisoa
Gliformin ke sethethefatsi sa lapeng ho phekoloa lefu la tsoekere la mofuta oa 2. A rekisoa ka mokhoa oa litafole tse nang le metformin e le eona feela motsoako o sebetsang (litekanyetso tsa 250 kapa 500 mg li ka etsahala). Gliformin e na le lethathamo le pharaletseng la li-contraindication, kahoo pele o qala kalafo, etsa bonnete ba ho bala litaelo tsa semmuso bakeng sa tšebeliso.
Analogue e theko e phahameng haholo ho tsoa ho li-ruble tse 119.
Moetsi: Vörwag Pharma GmbH & Co KG (Jeremane)
Mefuta ea Tsamaiso:
- Matlapa a 1000 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 176
- Letlapa 850 mg, li-pcs tse 60., Theko e tsoang ho li-ruble tse 190
Litaelo tsa ho sebelisoa
Setlhare se seng sa lefu la tsoekere ka tokollo ea foromo. E rekisitsoe ka har'a lipakete tsa likarete tsa 30 tse nang le metformin hydrochloride e le motsoako o sebetsang. Contraindred nakong ea bokhachane le nakong ea matsoele.
Analogue e theko e phahameng haholo ho tsoa ho li-ruble tse 121.
Moetsi: Hemofarm A.D. (Serbia)
Mefuta ea Tsamaiso:
- Tab. 500 mg, li-pcs tse 60., Theko e tsoang ho li-ruble tse 178
- Letlapa 850 mg, li-pcs tse 60., Theko e tsoang ho li-ruble tse 190
Litaelo tsa ho sebelisoa
Metformin ke lithethefatsi tsa Serbia hypoglycemic bakeng sa tšebeliso ea kahare. Ho hlophisoa ha matlapa ho na le motsoako o sebetsang oa lebitso le tšoanang ho litekanyetso tsa 500 kapa 850 mg. E laetsoe kalafo ea lefu la tsoekere la mofuta oa 2 (ho batho ba baholo), haholoholo maemong a botenya.
Analogue e theko e phahameng haholo ho tloha ho li-ruble tse 214.
Moetsi: Berlin-Chemie / Menarini Pharma GmbH (Duitsland)
Mefuta ea Tsamaiso:
- Tab. 500 mg, li-pcs tse 60., Theko e tsoang ho li-ruble tse 271
- Letlapa 850 mg, li-pcs tse 60., Theko e tsoang ho li-ruble tse 190
Litaelo tsa ho sebelisoa
Siofor ke litokisetso tsa letlapa la Jeremane le etselitsoeng ho phekola mofuta oa lefu la tsoekere la mofuta oa 2. Metformin hydrochloride e lekantsoeng ea 500 ho isa ho 1000 mg e sebelisoa e le ntho e sebetsang. E rekisitsoe ka mabokoseng a matlapa a 60.
Li-analog mabapi le sebopeho le pontšo ea ts'ebeliso
| Sehlooho | Theko ho la Russia | Theko Ukraine |
|---|---|---|
| Bagomet Metformin | -- | 30 UAH |
| Glucofage metformin | 12 rub | 15 UAH |
| Glucophage xr metformin | -- | 50 UAH |
| Reduxin Met Metformin, Sibutramine | 20 rub | -- |
| Dianormet | -- | 19 UAH |
| Diaformin metformin | -- | 5 UAH |
| Metformin metformin | 13 rub | 12 UAH |
| Metformin sandoz metformin | -- | 13 UAH |
| Siofor | 208 rub | 27 UAH |
| Foromo metformin hydrochloride | -- | -- |
| Emnorm EP Metformin | -- | -- |
| Megifort Metformin | -- | 15 UAH |
| Metamine Metformin | -- | 20 UAH |
| Metamine SR Metformin | -- | 20 UAH |
| Metfogamma metformin | 256 rub | 17 UAH |
| Tefor metformin | -- | -- |
| Glycometer | -- | -- |
| Glycomet SR | -- | -- |
| Metformin Canon metformin, ovidone K 90, starch ea poone, crospovidone, magnesium stearate, talc | 26 rub | -- |
| Insuffor metformin hydrochloride | -- | 25 UAH |
| Metformin-teva metformin | 43 rub | 22 UAH |
| Diaformin SR metformin | -- | 18 UAH |
| Mepharmil Metformin | -- | 13 UAH |
| Metformin Farmland Metformin | -- | -- |
Lethathamo le ka holimo la li-analogues tsa lithethefatsi, tse bonts'ang Sebelisa formetin, e loketse haholo hobane e na le sebopeho se tšoanang sa lintho tse sebetsang ebile e lumellana ho latela sesupo sa tšebeliso
Moetso o fapaneng o kanna oa lumellana ho bonts'a mokhoa le mokhoa oa ts'ebeliso
| Sehlooho | Theko ho la Russia | Theko Ukraine |
|---|---|---|
| Rosiglitazone e sebetsang, metformin hydrochloride | -- | -- |
| Glibenclamide Glibenclamide | 30 rub | 7 UAH |
| Maninyl Glibenclamide | 54 rub | 37 UAH |
| Glibenclamide-Health Glibenclamide | -- | 12 UAH |
| Glyurenorm glycidone | 94 rub | 43 UAH |
| Bisogamma Glyclazide | 91 rub | 182 UAH |
| Glidiab Glyclazide | 100 rub | 170 UAH |
| Diabeteson MR | -- | 92 UAH |
| Diagnizide mr Gliclazide | -- | 15 UAH |
| Glidia MV Gliclazide | -- | -- |
| Glykinorm Gliclazide | -- | -- |
| Gliclazide Gliclazide | 231 rub | 44 UAH |
| Glyclazide 30 MV-Indar Glyclazide | -- | -- |
| Glyclazide-Health Gliclazide | -- | 36 UAH |
| Glioral Glyclazide | -- | -- |
| Lekola Gliclazide | -- | 14 UAH |
| Diazide MV Gliclazide | -- | 46 UAH |
| Osliklid Gliclazide | -- | 68 UAH |
| Diadeon gliclazide | -- | -- |
| Glyclazide MV Gliclazide | 4 rub | -- |
| Amaril | 27 rub | 4 UAH |
| Glemaz glimepiride | -- | -- |
| Glian glimepiride | -- | 77 UAH |
| Glimepiride Glyride | -- | 149 UAH |
| Glimepiride diapiride | -- | 23 UAH |
| Aletare | -- | 12 UAH |
| Glimax glimepiride | -- | 35 UAH |
| Glimepiride-Lugal glimepiride | -- | 69 UAH |
| Clay glimepiride | -- | 66 UAH |
| Diabrex glimepiride | -- | 142 UAH |
| Meglimide glimepiride | -- | -- |
| Melpamide Glimepiride | -- | 84 UAH |
| Perinel glimepiride | -- | -- |
| Glempid | -- | -- |
| Ke thabo | -- | -- |
| Glimepiride glimepiride | 27 rub | 42 UAH |
| Glimepiride-teva glimepiride | -- | 57 UAH |
| Glimepiride Canon glimepiride | 50 rub | -- |
| Glimepiride Pharmacyard glimepiride | -- | -- |
| Dimaril glimepiride | -- | 21 UAH |
| Glamepiride diamerid | 2 rub | -- |
| Amaryl M Limepiride Micronized, Metformin Hydrochloride | 856 rub | 40 UAH |
| Glibomet glibenclamide, metformin | 257 rub | 101 UAH |
| Glucovans glibenclamide, metformin | 34 rub | 8 UAH |
| Dianorm-m Glyclazide, Metformin | -- | 115 UAH |
| Dibizid-m glipizide, metformin | -- | 30 UAH |
| Douglimax glimepiride, metformin | -- | 44 UAH |
| Duotrol glibenclamide, metformin | -- | -- |
| Gluconorm | 45 rub | -- |
| Glibofor metformin hydrochloride, glibenclamide | -- | 16 UAH |
| Avandamet | -- | -- |
| Avandaglim | -- | -- |
| Janumet metformin, sitagliptin | 9 rub | 1 UAH |
| Velmetia metformin, sitagliptin | 6026 rub | -- |
| Galvus Met vildagliptin, metformin | 259 rub | 1195 UAH |
| Tripride glimepiride, metformin, pioglitazone | -- | 83 UAH |
| Comboglize XR metformin, saxagliptin | -- | 424 UAH |
| Comboglyz Prolong metformin, saxagliptin | 130 rub | -- |
| Gentadueto linagliptin, metformin | -- | -- |
| Vipdomet metformin, alogliptin | 55 rub | 1750 UAH |
| Sinjardi empagliflozin, metformin hydrochloride | 240 rub | -- |
| Voglibose Oxide | -- | 21 UAH |
| Glutazone pioglitazone | -- | 66 UAH |
| Dropia Sanovel pioglitazone | -- | -- |
| Januvia sitagliptin | 1369 rub | 277 UAH |
| Galvus vildagliptin | 245 rub | 895 UAH |
| Onglisa saxagliptin | 1472 rub | 48 UAH |
| Nesina alogliptin | -- | -- |
| Vipidia alogliptin | 350 rub | 1250 UAH |
| Trazhenta linagliptin | 89 rub | 1434 UAH |
| Lixumia lixisenatide | -- | 2498 UAH |
| Gum ea guar | 9950 rub | 24 UAH |
| Insvada repaglinide | -- | -- |
| Novonorm Repaglinide | 30 rub | 90 UAH |
| Repodiab Repaglinide | -- | -- |
| Baeta Exenatide | 150 rub | 4600 UAH |
| Baeta Long Exenatide | 10248 rub | -- |
| Viktoza liraglutide | 8823 rub | 2900 UAH |
| Saxenda liraglutide | 1374 rub | 13773 UAH |
| Forksiga Dapagliflozin | -- | 18 UAH |
| Forsiga Dapagliflozin | 12 rub | 3200 UAH |
| Invocana canagliflozin | 13 rub | 3200 UAH |
| Jardins Empagliflozin | 222 rub | 566 UAH |
| Trulicity Dulaglutide | 115 rub | -- |
U ka fumana analogue e theko e tlaase ea moriana o theko e phahameng?
Ho fumana analogue e theko e phahameng ea moriana, mofuta o tšoanang kapa oa mantsoe, pele ho tsohle re khothaletsa ho ela hloko sebopeho, e leng lintho le lipontšo tse tšoanang tse sebetsang. Metsoako e tšoanang ea lithethefatsi e tla bonts'a hore lithethefatsi li tsamaisana le lithethefatsi, li ka lekana meriana kapa li ka etsa meriana. Leha ho le joalo, u se ke oa lebala ka likarolo tse sa sebetseng tsa lithethefatsi tse tšoanang, tse ka amang polokeho le ts'ebetso. Se ke la lebala ka litaelo tsa lingaka, ho itlama ho ka lematsa bophelo ba hau, ka hona, etela ngaka ea hau kamehla pele u sebelisa meriana leha e le efe.
Melemo e nepahetseng ea ho hlophisoa ha letlapa
Matšoao a sehlooho a ts'ebeliso ea moriana o joalo ke a latelang:
- ho ba teng ha metabolic syndrome kapa lipontšo tsa ho hanyetsa insulin,
- e le molao, boteng ba insulin ho hanyetsa, botenya bo ntse bo eketseha ka potlako ho bakuli, ka lebaka la litlamorao tsa metformin le ho shebella phepo e khethehileng ea phepo e nepahetseng, ho fokotsa boima ba 'mele ho ka fihlelleha,
- haeba ho na le tlolo ea mamello ea tsoekere.
- hlaha ovary ea popopolycystic
- insulin e itšetlehileng ka lefu la tsoekere e le monotherapy kapa karolo ea kalafo e rarahaneng,
- mofuta o itšetlehileng ka insulin o kopane le liente tsa insulin.
Haeba re bapisa Foromo ea lithethefatsi le lithethefatsi tse ling tse fokotsang tsoekere, melemo e latelang ea metformin e lokela ho totobatsoa:
- Phello ea eona ea ho fokotsa khatello ea insulin ho mokuli. Metformin hydrochloride e khona ho eketsa kutloisiso ea lisele le lisele ho glucose e hlahisoang ke manyeme.
- Ho nwa moriana o tsamaisana le ho monya ha ona ke litho tsa thipa ea ka mpeng. Kahoo, ho fokotsa ho monya ha glucose ke mala ho ea phethahala.
- E thusa ho thibela tsoekere ea "gluconeogeneis", e bitsoang ts'ebetso ea matšeliso ea glucose.
- E thusa ho fokotsa takatso ea lijo, e bohlokoa haholo bakeng sa batho ba nang le lefu la tsoekere le boima haholo.
- E na le phello e ntle ho k'holeseterole, e fokotsa bobe ebile e eketsa botle.
Ntle le moo, moriana o thusa ho khelosa tšebetso ea mafura.
Litaelo tsa ho sebelisoa ha matlapa
Litaelo tsa formethine bakeng sa ts'ebeliso li na le polelo ea hore moriana o fumaneha ka foromo ea letlapa ka mokhoa oa matlapa a biconvex tšoeu.
Sebopeho sa lithethefatsi se kenyelletsa ntho e sebetsang ea Metformin hydrochloride le likarolo tse thusang ka sebopeho sa magnesium stearate, povidone le croscarmellose sodium.
Litekanyetso tse latelang tsa lithethefatsi li hlahisoa 'marakeng oa pharmacological - 0.5 g, 0,85 g le 1 g ea ntho e sebetsang. Ho latela boholo ba hyperglycemia, ngaka e fana ka lethal dose e hlokahalang ea meriana. Matlapa ohle a formin a ka rekoa ka mabokoseng a likotoana tsa 30, 60 kapa 120. Tšebeliso ea bona e ka etsahala feela joalo ka ha ho laetsoe ke ngaka e eang (kajeno basali ba bangata ba sebelisa mokhoa oa ho theola boima ba 'mele).
Mokhoa oa tsamaiso le litekanyetso li behiloe bakeng sa mokuli ka mong, ho ipapisitsoe le liparamente tse joalo:
- botebo ba methapo ea methapo le boemo ba khatello ea tsoekere maling maling
- sehlopha sa boima ba mokuli le lilemo tsa hae
- boteng ba maloetse a kopaneng.
Pele o qala kalafo, ho kgothaletswa ho etsa tlhahlobo e hlokahalang ea tlhahlobo le ho nka liteko ho bona likotsi tse ka hlahang le lipontšo tsa karabelo e mpe ha o sebelisa moriana.
The drugmetmetin, joalo ka molao, e nkuoa ho latela merero e latelang:
- Ka molomo kamora lijo, ho nwa metsi a mangata.
- Pheko ea ho qala e lokela ho qala ka tekanyo e tlase ea ntho e sebetsang mme e be limiligrama tse makholo a mahlano ka letsatsi.
- Qetellong ea nako (hangata kamora nako ea libeke tse peli), ngaka e eang, e ipapisitse le liphetho tsa liteko le palo ea tsoekere maling maling, e etsa qeto ea ho fetola litekanyetso tsa moriana. Re lokela ho hopola hore tekanyetso ea letsatsi le letsatsi e fapana ho tloha ho 500 ho isa ho 1000 mg ea ntho e sebetsang ea metformin hydrochloride.
- Phekolo e phahameng ka ho fetisisa ea lithethefatsi tse khabisitsoeng ka letsatsi ha ea lokela ho feta 3000 mg ea motsoako o sebetsang, ho batho ba baholo palo ena ke 1000 mg.
O ka nka formin hang kapa makhetlo a 'maloa ka letsatsi, ho latela litekanyetso li thehiloe.
Haeba mokuli a hloka tekanyetso e kholo ea moriana, ho molemo hore a arole ho ja ka makhetlo a 'maloa ka letsatsi.
Lipontšo tse mpe tsa lithethefatsi
Setlhare se ka ama 'mele, se bonts'a litla-morao tsa sona tse mpe ka tsela ea litla-morao.
Bakeng sa ho fokotsa kotsi ea ho hlaha ha bona, ho bohlokoa ho latela litaelo tsohle tsa setsebi sa bongaka.
Ho khothaletsoa ka mokhoa o ikhethileng hore o itloaelanye le tlhaiso-leseling e fumanehang letlapeng.
Litlamorao tse mpe tse ka hlahang ka lebaka la ho nka litafole tsa Formetin, ho sa tsotelehe litekanyetso li nka:
- ho hlaha hoa mathata a fapaneng ka mokhoa oa "gastrointestinal". Pele ho tsohle, ke matšoao a kang ho nyekeloa le pelo le ho hlatsa, lets'ollo, ho thunya le bonolo ba mpa.
- moriana o eketsa kotsi ea anorexiaꓼ
- mohlomong phetoho ea tatso, e bonahatsoang ke ho ba le tatso e sa thabiseng ea tšepe mokokotlong oa molomo
- ho fokotseha ha palo ea livithamini B, ho u qobella ho nka lithethefatsi tse ling ka litlatsetso tsa meriana
- pontsho ya anemiaꓼ
- ka litheko tse kholo tsa ts'ebetso, ho ka ba le kotsi ea hypoglycemiaꓼ
- Mathata le letlalo, haeba ho na le ponahatso ea karabelo e itseng ho sekhoeng se nooang.
Bakuli ba bang ba fumana hore formin ke lithibela-mafu. Ebile, moriana ha se oa sehlopha se joalo sa lithethefatsi. Ka nako e ts'oanang, ho bana, ts'ebeliso ea moriana ho felisa hyperglycemia e thibetsoe.
Litla-morao li ka boela tsa hlaha ka lebaka la tšebeliso e mpe ea lithethefatsi kapa ka litlhare. Ho kopanya Foromo le lisebelisoa tse ling tsa bongaka (ka mokhoa oa litafole, ho emisoa, tharollo ea ente ea lihlopha tse fapaneng le lihlopha) ho ka etsahala feela ka tumello ea setsebi sa bongaka.
Lithibelo mabapi le tšebeliso ea moriana ke eng?
Li-contraindication tsa formethine li bontšoa ka lekhapetleng ho ea ho litokisetso tse ngotsoeng.
Moetsi o tsebisa batho bohle bao e ka bang bareki ka ho qaqileng ka linyeoe tseo ho sa lumelloeng ho sebelisa lithethefatsi ho tsona.
Ntle le moo, litaelo li boetse li na le tlhahisoleseling ea hore na formmetin e lumellana le meriana le lintho life.
Ha hoa lumelloa ho sebelisa moriana haeba ho tsebahala lintlha tse latelang:
- Acidosis ka mefuta e hlobaetsang kapa e sa foleng.
- Banana nakong ea ho beleha ngoana kapa ho anyesa.
- Bakuli ba lilemo tsa ho tlohela mosebetsi, haholo kamora lilemo tse mashome a tšeletseng a metso e mehlano.
- Ho se mamellane ha motsoako oa lithethefatsi, kaha ho ka khoneha hore ho be le lintho tse bohloko tse kulang haholo.
- Haeba mokuli a fumanoa a e-na le bothata ba pelo.
- Ka lefu la pelo le fetileng le lefu la tsoekere.
- Haeba hypoxia e etsahala.
- Nakong ea ho omella, e ka hlahisoang hape ke li-pathologies tse fapaneng tsa tšoaetso.
- Ho ikoetlisa ka matla.
- Mafu a ka mpeng, ho kenyelletsa le boteng ba ulc.
- Ho hloleha ha sebete.
Ntle le moo, motsoako oa kalafo ea kalafo le joala (joala ponong efe kapa efe) ha oa amoheleha.
Haeba mokuli a e-na le ts'ebetso ea liphio, menyetla ea ho ba le lactic acidosis e ka eketseha, kaha palo e kholo ea lactic acid 'meleng e qala ho bokellana.
Tlhahlobo ea litsebi tsa bongaka le bakuli le lingaka
Tlhaloso ea sebopeho sa litheolelo tsa foromo le litlhahlobo tse ngata tsa bareki li bonts'a ts'ebetso ea eona e phahameng.
Ntle le moo, bakuli ba bangata ba bonts'a mamello e bonolo ea moriana le ho se be le litlamorao tse fapaneng.
Formetin e na le theko ho li-drug tsa li-ruble tse lekholo 'me ho latela lintlha tse' maloa.
Lintho tse susumetsang litšenyehelo tsa lithethefatsi ke tse latelang:
- palo ea litafole ka pakete e ngoe le e ngoe
- litekanyetso tsa ntho e sebetsang
- toropo ea thekiso le boqapi ba meriana.
Litsenyehelo tsa formin ke taelo ea boholo bo tlase ho feta lithethefatsi tse ling tse nang le motsoako o sebetsang oa metformin hydrochloride. Ke kahoo, hangata litsebi tsa bongaka li khothaletsang ho sebelisa sesebelisoa sena ho fetofatsa glycemia ho lefu la tsoekere. Maikutlo a lingaka mabapi le phello e ntle boemong ba glucose maling, ho se nke lehlakore hoa nts'etsopele ea insulin ho hana, ho re lumella ho fihlela qeto ea hore Formetin ke khetho ea tekanyetso e tlisa sephetho se setle.
Li-analogu tsa formimetin 'marakeng oa pharmacological li hlahisoa ka bongata. Tsena li kenyelletsa litlhare tse tšoanang le lithethefatsi tse tšoanang, tse ka bang le sebopeho se fapaneng, empa li na le litlamorao tse ts'oanang. Ha o batla ho nka sebaka, o lokela ho fumana keletso ea ngaka ea hau e ka khothaletsang khetho e nepahetseng ka ho fetisisa.
Lihlahisoa tse latelang tsa meriana li kenyellelitsoe ka palo ea li-analog tsa Formetin:
Lithethefatsi tsohle tse kaholimo li har'a litafole tse fokotsang tsoekere tse nang le phello ea hypoglycemic. Sesebelisoa sa mantlha se sebetsang ke metformin hydrochloride. Lithethefatsi tse joalo ha li fapana le Foromo. Phapang e ka tsamaisana le palo ea litla-morao kapa li-contraindication tse bontšitsoeng, hammoho le litšenyehelo tsa moriana.
Ka linako tse ling, formin e khethoa e le kalafo e kopaneng e sebelisang lithethefatsi tse kang atorvastatin kapa glycine.
Ke lithethefatsi life tsa lefu la tsoekere tse tla thusa ho fetisa tsoekere ea mali, setsebi se tla bolela videong ena.
Formetin: litaelo tsa tšebeliso, theko, analogues
Formetin ke sethethefatsi se sebetsang sa metformin hydrochloride. Tekanyetso: 0.5 g, 0,85 g kapa 1 g. Analogs: Gliformin, Metadiene, Nova Met, NovoFormin, Siofor, Sofamet.
Lintho tse thusang: croscarmellose sodium, povidone (polyvinylpyrrolidone e leka-lekaneng ea molek'hule), magnesium stearate bakeng sa indasteri ea meriana.
Sebopeho sa ho lokolloa: matlapa a masoeu a chitja a cylindrical a masoeu a nang le facet le kotsi (litekanyetso tsa 0.5 g) le matlapa a tšoeu a oval biconvex a nang le kotsi ka lehlakoreng le le leng (litekanyetso tsa 0,85 g le 1,0 g).
Matšoao a pharmacological
Forethine e fokotsa ho monya ha tsoekere e ka mpeng, e thibela tšebetso ea gluconeogeneis ka har'a sebete, e ntlafatsa tlhahiso ea glucose e tsoang, mme e eketsa kutloisiso ea lithane ho litokisetso tsa insulin.
Maemong ana, formethine:
- Ha e ame tlhahiso ea insulin ke lisele tsa beta tse fumanehang manyeme.
- Ha e qholotsa nts'etsopele ea boemo ba hypoglycemic.
- Fokotsa palo ea lipoprotein tse fokolang haholo le triglycerides maling.
- E fokotsa boima ba 'mele, e tiisa boima ba' mele ka mokhoa o tloaelehileng.
- E na le phello ea fibrinolytic ka lebaka la khatello ea activator ea tisy ea plasminogen.
Formaline, kamora ho tsamaisoa ka molomo, e kenella butle butle ho tsoa pampiring ea mala. Palo ea lihlahisoa tse fumanehang ka mor'a ts'ebeliso ea tekanyetso e tloaelehileng e ka ba 60%.
Khokahano ea tlhapi ea moriana maling e hlaha lihora tse 2,5 kamora ts'ebeliso ea kahare.
Forthine e batlang e sa kopanye le liprotheine tsa plasma, e bokellana sebeteng, liphio, mesifa, litšoelesa tsa salivary, 'me e nkoe ke liphio ka mokhoa o sa nepahalang. Bophelo ba ntho e halofo ke lihora tse 1.5 - 4.5.
Ela hloko! Haeba mokuli a sitisitse tšebetso ea renal, ho bokelloa hoa moriana 'meleng hoa khoneha.
Matšoao a ho sebelisoa
Litlhare li fuoe mofuta oa lefu la tsoekere la mofuta oa 2, ha phekolo ea lijo e sa tlise litholoana tse ntle (ho bakuli ba nang le botenya), sena sohle se bontšoa ke litaelo tsa lithethefatsi.
Litekanyetso tsa lithethefatsi li fanoa ke ngaka ka bonngoe ho mokuli ka mong. Phapang ea litekanyetso li bakoa ke ho kenella ha tsoekere maling. Matlapa a formethine a lokela ho nooa nakong ea ha mokuli a qeta ho ja lijo, ntle le ho hlafuna le ho noa metsi a mangata.
Boemong ba pele ba kalafo, tekanyetso e lokela ho ba 0,85g. Nako e le 1 ka letsatsi kapa 0.5g. Makhetlo a 1-2 ka letsatsi. Butle-butle eketsa tekanyetso ho 3g. ka letsatsi.
Bohlokoa! Bakeng sa bakuli ba tsofetseng, tloaelo ea letsatsi le letsatsi ha ea lokela ho feta 1g. Ka lebaka la kotsi e kholo ea lactic acidosis, ka metabolism e matla ea metabolic, lethal dose e lokela ho fokotsoa.
Litlhahiso tse khethehileng tsa tšebeliso
Litaelo: nakong ea kalafo, o hloka ho sebelisa taolo e nepahetseng holim'a ts'ebetso ea meno. Hang kamora likhoeli tse ling le tse ling tse tšeletseng le ka nts'etsopele ea myalgia, ho hlokahala ho tseba hore na lactate e kae ka plasma.
Formetin e ka sebelisoa hammoho le lintho tse tsoang ho sulfonylurea. Tabeng ena, ho hlahlojoa ka hloko ha tsoekere ea mali ho hlokahala.
Foromo ka nako ya monotherapy ha e ame bokhoni ba ho sebetsa ka mechini e rarahaneng le ho khanna likoloi. Haeba moriana o kopantsoe le lithethefatsi tse ling tsa hypoglycemic, ho ka etsahala hore nts'etsopele ea hypoglycemia, moo ho se nang bokhoni ba ho khanna koloi le ho sebetsa ka mekhoa e rarahaneng e hlokang tlhokomelo e phahameng.
Lintho tse fapaneng tse tla etsahala
Ho tsoa ts'ebetsong ea tšilo ea lijo:
- tatso ea tšepe
- ho nyekeloa, ho hlatsa,
- botlaela, lets'ollo,
- tahlehelo ea takatso ea lijo
- bohloko ba ka mpeng.
Ho tsoa lithong tsa hemopoietic maemong a mang meia ea methapo ea methapo e bonoa.
Mabapi le metabolism:
- e hlokang ho khaotsa ho phekoloa, lactic acidosis ha e fumanehe,
- ka kalafo ea nako e telele, ho hlaha hypovitaminosis B12.
Sistimi ea endocrine ka tekanyetso e sa lekaneng e ka arabela ka hypoglycemia.
Liponahatso tsa ho kula: lekhopho la letlalo.
Ho sebelisana le lithethefatsi tse ling
Phello ea hypoglycemic ea metformin e ka ntlafatsoa ha e sebelisoa ka nako e tšoanang le:
- insulin
- sulfonylurea derivatives,
- oxytetracycline
- acarbose
- Lithethefatsi tse senang ts'oaetso tsa li -idalidal
- cyclophosphamide
- Angiotensin -
- monoamine oxidase inhibitors
- Metsi-a-block
- derivatives of clofibrate.
Ho fokotseha ha phello ea hypoglycemic ea metformin ho bonoa ka tšebeliso e tšoanang le:
- "Loop" le thiazide diuretics,
- lithibela-pelehi tsa molomo
- glucocorticosteroids,
- glucagon
- epinephrine
- phenothiazine derivatives,
- kutloelo-bohloko
- nicotinic acid e tsoang ho
- lihormone tsa qoqotho.
Contraindication
U ke ke ua nka formin ka:
- Ho senyeha ha real,
- lefu la tsoekere ketoacidosis, thoroma, koma,
- phefumoloho le ho hloleha ha pelo,
- ho omella
- kotsi e mpe ea methapo ea pelo
- bokuli bo sa foleng le maemo a mang a tlatsetsang kholisong ea lactic acidosis,
- nakong ea bokhachane le pelehi,
- hypersensitivity ho likarolo tsa moriana,
- likotsi le ts'ebetso e kholo ea ts'ebetso ea bongaka
- mafu a tšoaetsanoang haholo
- joala bo bongata haholo
- lactic acidosis.
Taeo e tsamaeang le eona e re tšebeliso ea Foromo e sa lokela ho tla pele ho lithuto tsa radiology le radioisotope ka kenyelletso ea ntho e nang le iodineine e fapaneng nakong ea matsatsi a mabeli.
Formethine ha e khothalletsoe hore e sebelisoe ke batho ba fetang 60 ba etsang mosebetsi o boima oa 'mele. Haeba molao ona o sa bonoe, bakuli ba joalo ba ka ba le lactic acidosis.
Seo thuto ea overdose e se buang
Litaelo bakeng sa lithethefatsi Forame ea litlolo li lemosa hore ka ho fetella, ho na le monyetla oa ho holisa lactic acidosis ka sephetho se bolaeang. Sesosa sa boemo bona e kanna ea bokellana ha moriana 'meleng ka lebaka la ts'ebetso ea renal e sa sebetseng.
Matšoao a latelang ke matšoao a mantlha a lactic acidosis:
- Ho nyekeloa ke pelo, ho hlatsa.
- Letšollo, bohloko ba ka mpeng.
- Bofokoli, hypothermia.
- Tsietsing
- Bohloko ba mesifa.
- Reflex bradyarrhythmia.
- Ho theola khatello ea mali.
- Ho sithabela maikutlo le ho holofala
Haeba mokuli a e-na le matšoao a mantlha a lactic acidosis, Foromo e lokela ho qheleloa ka thoko mehatong ea kalafo, mokuli o lokela ho fetisetsoa sepetlele moo ngaka e khonang ho tseba hore na o na le lactate e kae ebe e etsa tlhahlobo e sa utloahaleng.
Mokhoa o sebetsang haholo oa ho tlosa metformin le lactate 'meleng ke hemodialysis, hammoho le kalafo ea matšoao.
Foromo - polokelo, theko
Bophelo ba Shelf ba moriana ke likhoeli tse 24, ka mor'a moo Foromo e ke ke ea sebelisoa. Setlhare ke sa lethathamo la B. E tlameha ho bolokoa sebakeng se lefifi se sa fumanehe ho bana ka mocheso o sa feteng 25 ° C.
Fomu ea tokollo - matlapa a 850 mg. Likotoana tse 60.
Fomu ea tokollo - matlapa a 1gr. Likotoana tse 60.
Tse ling tsa li-analogu li theko e boima haholo.
Moriana oa molomo oa hypoglycemic
Fomu ea tokollo, sebopeho le sephutheloana
Lipilisi tšoeu, pota, cylindrical e boreleli, e nang le bevel le notch.
| 1 tab | |
| metformin hydrochloride | 0.5 g |
Baeti: povidone (polyvinylpyrrolidone e boima bohareng, povidone K-30) - 0,017 g, croscarmellose sodium (primellose) - 0,008 g, magnesium stearate - 0,005 g.
Li-pcs tse 10. - liphutheloana tsa lithutsoana (6) - lipakete tsa karete
Lipilisi tšoeu, pota, cylindrical e boreleli, e nang le bevel le notch.
| 1 tab | |
| metformin hydrochloride | 0.5 g |
Baeti: povidone (polyvinylpyrrolidone e boima bohareng, povidone K-30) - 0,017 g, croscarmellose sodium (primellose) - 0,008 g, magnesium stearate - 0,005 g.
Li-pcs tse 10. - liphutheloana tsa lithutsoana (6) - lipakete tsa karete.
Lipilisi tšoeu, oval, biconvex, e nang le notch lehlakoreng le le leng.
| 1 tab | |
| metformin hydrochloride | 0.85 g |
Baeti: povidone (polyvinylpyrrolidone e boima bohareng, povidone K-30) - 0,029 g, croscarmellose sodium (primellose) - 0,0136 g, magnesium stearate - 0,0084 g.
Li-pcs tse 10. - liphutheloana tsa lithutsoana (6) - lipakete tsa karete.
Lipilisi tšoeu, oval, biconvex, e nang le notch lehlakoreng le le leng.
| 1 tab | |
| metformin hydrochloride | 0.85 g |
Baeti: povidone (polyvinylpyrrolidone e boima bohareng, povidone K-30) - 0,029 g, croscarmellose sodium (primellose) - 0,0136 g, magnesium stearate - 0,0084 g.
Li-pcs tse 10. - liphutheloana tsa lithutsoana (6) - lipakete tsa karete.
Lipilisi tšoeu, oval, biconvex, e nang le notch lehlakoreng le le leng.
| 1 tab | |
| metformin hydrochloride | 1 g |
Baeti: povidone (polyvinylpyrrolidone e bohareng ba boima ba 'mele, povidone K-30) - 0,034 g, croscarmellose sodium (primellose) - 0,016 g, magnesium stearate - 0,01 g.
Li-pcs tse 10. - liphutheloana tsa lithutsoana (6) - lipakete tsa karete.
Lipilisi tšoeu, oval, biconvex, e nang le notch lehlakoreng le le leng.
| 1 tab | |
| metformin hydrochloride | 1 g |
Baeti: povidone (polyvinylpyrrolidone e bohareng ba boima ba 'mele, povidone K-30) - 0,034 g, croscarmellose sodium (primellose) - 0,016 g, magnesium stearate - 0,01 g.
Li-pcs tse 10. - liphutheloana tsa lithutsoana (6) - lipakete tsa karete.
Ketso ea pharmacological
Setlhare sa molomo sa hypoglycemic se tsoang sehlopheng sa Biguanide. E thibela gluconeogenesis ka har'a sebete, e fokotsa ho monya ha tsoekere ka mpeng, e ntlafatsa ts'ebeliso ea tsoekere, hape e eketsa kutloisiso ea lisele tsa mmele ho insulin. Ha e ame secretion ea insulin ke lisele tsa β-cell tsa manyeme, ha e bake karabelo ea hypoglycemic.
Lowers triglycerides le LDL.
E tsitsisa kapa e theola boima ba 'mele.
E na le phello ea fibrinolytic ka lebaka la khatello ea inhibitor ea tisy ea plasminogen activator.
Mofumahali
Kamora ho tsamaisoa ka molomo, metformin e nkuoa ho tsoa mokokotlong oa lijo. Bioavailability kamora ho nka tekanyetso e tloaelehileng ke 50-60%. Cmax kamora hore tsamaiso ea molomo e fihlelisoe kamora lihora tse 2,5.
Ha e lumellane le liprotheine tsa plasma. E bokellana ka har'a litšoelesa tse qhekellang, mesifa, sebete le liphio.
E tšolotsoe e sa fetoha moroto. T1 / 2 ke lihora tse 1.5-4,5.
Pharmacokinetics maemong a khethehileng a kliniki
Ka ts'ebetso ea renal e sa sebetseng hantle, ho sebelisoa hoa lithethefatsi hoa khoneha.
- Mofuta oa 2 oa lefu la tsoekere le ho se sebetse hantle hoa kalafo ea ho ja (haholoholo ho bakuli ba nang le botenya).
Contraindication
- lefu la tsoekere ketoacidosis, lefu la tsoekere, leta,
- Ho senyeha ha renal,
- maemo a ka kenyang letsoho kholisong ea lactic acidosis, ho kenyelletsa ho nyekeloa ke pelo le ho phefumoloha, karolo e mpe ea lefu la pelo, ho hlaseloa ke kotsi e mpe ea pelo, ho felloa ke metsi, ho lemalla joala bo sa foleng,
- ts'ebetso ea ho se sebetse hantle ha sebete,
- chefo e mpe ea joala,
- mafu a tšoaetsanoang a matla,
- lactic acidosis (ho kenyeletsoa le nalane),
- ts'ebetso e matla ea ho buoa le ho tsoa likotsi (maemong ana, ho bontšoa kalafo ea insulin),
- Sebelisa pele ho matsatsi a mabeli pele le ka mor'a matsatsi a 2 ho etsa lithuto tsa radioisotope kapa X-ray ka tlhahiso ea iodine e nang le phapang e mahareng.
- ho latela mokhoa oa ho ja lijo tse nang le khalori e tlase (ka tlase ho 1000 cal / ka letsatsi),
- ho anyesa (matsoele),
- Hypersensitivity ho likarolo tsa moriana.
Ha ho kgothaletswe ho sebelisa lithethefatsi ho bakuli ba lilemo tse fetang 60 ba etsang mosebetsi o boima oa 'mele, ka lebaka la kotsi e eketsehang ea lactic acidosis.
Beha ka bomong, o ela hloko boemo ba glucose maling.
Motsoako oa pele ke 500 mg ka makhetlo a 1-2 / ka letsatsi kapa 850 mg 1 nako / letsatsi. Kamora nako, butle-butle (1 nako ka beke), lethal dose le eketseha ho isa ho 2-3 g / ka letsatsi. Sekhahla se phahameng sa letsatsi ke 3 g.
Ho bakuli ba tsofetseng Tekanyetso ea letsatsi le letsatsi ha ea lokela ho feta 1 g.
Ka lebaka la kotsi e eketsehang ea lactic acidosis, ha u tsamaisa metformin ho bakuli ba nang le mathata a tebileng a metabolic, lethal dose le lokela ho fokotsoa.
Matlapa a lokela ho nooa nakong ea lijo kapa ka mor'a lijo, ntle le ho hlafuna le ho noa metsi a mangata.
Ho tsoa ts'ebetsong ea tšilo ea lijo: ho nyekeloa ke pelo, ho hlatsa, ho “latsoa” molomong, ho hloka takatso ea lijo, lets'ollo, ho hlonepha, bohloko ba ka mpeng.
Ka lehlakoreng la metabolism: ka seoelo - lactic acidosis (e hloka ho khaotsa ho phekoloa), ka ts'ebeliso ea nako e telele - B12 hypovitaminosis (malabsorption).
Ho tsoa ho sheropoietic system: maemong a mang - anemia ea megaloblastic.
Ho tsoa tsamaisong ea endocrine: hypoglycemia (ha e sebelisoa ka tekanyetso e sa lokang).
Litla-morao: lekhopho la letlalo.
Bongata
Matšoao lefu la lactic acidosis le ka hlaha. Sesosa sa nts'etsopele ea lactic acidosis le eona e ka ba ho lutla ha moriana ka lebaka la ts'ebetso ea renal e sa sebetseng.
Matšoao a pele a lactic acidosis ke bofokoli bo akaretsang, ho nyekeloa ke pelo, ho hlatsa, lets'ollo, ho fokotsa mocheso oa 'mele, bohloko ba ka mpeng, bohloko ba mesifa, ho theola khatello ea mali, Reflex bradyarrhythmia, nakong e tlang e ka eketsa ho hema, ho tsekela, ho hloka kelello ho tebileng le ho holofala ha lets'oaetso.
Phekolo: haeba ho na le matšoao a lactic acidosis, kalafo e nang le metformin e lokela ho emisoa hang-hang, mokuli a le sepetlele ka potlako mme ha a se a lemohile hore o na le lactate, o netefatsa tlhahlobo eo. Hemodialysis e sebetsa hantle haholo bakeng sa ho tlosa lactate le metformin 'meleng. Haeba ho hlokahala, etsa kalafo e nang le matšoao.
Ho sebelisana le lithethefatsi
Ka ts'ebeliso e le 'ngoe le sulfonylurea derivatives, acarbose, insulin, NSAIDs, li-inhibitors tsa MAO, oxetetracycline, li-inhibitors tsa ACE, li-derifatives tse tsoang ka har'a marang-rang, cyclophosphamide le beta-blockers, ho khonahala ho eketsa phello ea hypoglycemic ea metformin.
Ka tšebeliso e le 'ngoe le GCS, lithibela-pelehi tsa molomo, epinephrine (adrenaline), sympathomimetics, glucagon, lihomone tsa qoqotho, thiazide le "loop" diuretics, li-phenothiazine tse tsoang le nicotinic acid, ho fokotseha hoa phello ea hypoglycemic ea metformin ho ka etsahala.
Cimetidine e liehisa ho felisoa ha metformin, ka lebaka leo kotsi ea lactic acidosis e eketsehang.
Metformin e ka fokolisa phello ea li-anticoagulants (tse tsoang ho coumarin).
Ka tsamaiso e ts'oanang ka ethanol, nts'etsopele ea lactic acidosis e khonahala.
Ka tšebeliso ea nako e tšoanang ea nifedipine e eketsa ho amoheloa ha metformin le Cmax, e liehisa ho tebela.
Lithethefatsi tsa cationic (amlodipine, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamteren, vancomycin) tse fumanehang ka har'a marang-rang li qothisana le litsamaiso tsa tsamaiso ea lefutso mme, ka kalafo ea nako e telele, li ka eketsa Cmax ea lithethefatsi ka 60%.
Litaelo tse khethehileng
Nakong ea ts'ebeliso ea lithethefatsi, matšoao a ts'ebetso ea renal a lokela ho hlahlojoa. Bonyane makhetlo a 2 ka selemo, hammoho le ponahalo ea myalgia, litaba tsa lactate tse ho plasma li lokela ho ikemisoa.
Hoa khonahala ho sebelisa Formetin hammoho le lintho tse tsoang ho sulfonylurea, 'me ho hlokahala haholo ho lekola maemo a tsoekere ea mali.
Tšusumetso ho bokhoni ba ho khanna makoloi le litsamaiso tsa taolo
Ha e sebelisoa e le monotherapy, lithethefatsi ha li ame bokhoni ba ho khanna makoloi le ho sebetsa ka methapo.
Ka ho kopantsoe ha Formetin le lithethefatsi tse ling tsa hypoglycemic (sulfonylurea derivatives, insulin), maemo a hypoglycemic a ka hlaha moo bokhoni ba ho khanna makoloi le mesebetsi e meng e ka bang kotsi e hlokang tlhokomelo e potlakileng le lebelo la karabelo ea psychomotor le ho feta.
Lokolla liforomo le sebopeho
Ho na le mofuta oa pilisi ea moriana. Ka pakete ea karete e ka ba matlapa a 30, 60 kapa 100. Ka mokhoa oa ho emisa le mefuta e meng ea pharmacological, moemeli ha a hlahisoe.
Ntho e sebetsang ke metformin hydrochloride ka bongata ba 500, 850 kapa 1000 mg. Lintho tse ling tsa moriana ke:
- sodium hammart
- magnesium stearate,
- polyvinylpyrrolidone.
Ho na le mofuta oa pilisi ea moriana. Ka pakete ea karete e ka ba matlapa a 30, 60 kapa 100. Ka mokhoa oa ho emisa le mefuta e meng ea pharmacological, moemeli ha a hlahisoe.
Ke moemeli oa hypoglycemic e etselitsoeng ho fihlela lipheo tse latelang:
- Ho ntlafatsa ts'ebeliso ea tsoekere,
- ho fokotsa tšebetso ea tsoekere e amang sebete,
- ho eketsa kutloisiso ea lisele tsa kahare ho litlamorao tsa insulin (ka hona, tloaelo ea tsoekere ea mali e fihletsoe),
- boima ba 'mele
- fokotseha boemo ba lipoprotein tse fokolang le "triglycerides"
- fokotsa ho monya ha tsoekere e ka mpeng.
Ntle le moo, moriana ona ha o ame ho pateloa ha insulin manyeme ebile ha o lebise ho maikutlo a tsoang ka ntle ho hypoglycemic.
Bophelo E phela ho isa ho 120. Metformin. (03/20/2016)
Matlapa a thelisang tsoekere a Metformin
Mokhoa oa ho nka FORMETINE
Litekanyetso tsa lithethefatsi li khethoa ka bonngoe, ho latela matšoao a glucose maling a mokuli. Qala ka boholo ba 500 mg makhetlo a 1-2 ka letsatsi kapa tšebeliso e le 'ngoe ea 850 mg ea moriana.
Butle-butle, tekanyetso e eketsoa ho 2-3 g ka letsatsi. Palo e phahameng ea lithethefatsi ha ea lokela ho feta 3 g ka letsatsi.
Litekanyetso tsa lithethefatsi li khethoa ka bonngoe, ho latela matšoao a glucose maling a mokuli.
Pele o ja le ka mor'a lijo
Ho amohela Recetin ho ka etsoa ka mora lijo, le nakong ea lijo. Moriana o lumelloa ho nooa ka metsi.
Ho khothalletsoa ho sebelisa moriana mantsiboea, o tla qoba litlamorao tse mpe tse tsoang mpeng ea mpa. Ha u sebelisa lithethefatsi makhetlo a mabeli ka letsatsi, moriana o nooa hoseng le ka shoalane.
Phekolo ea ka mpeng
Ka nts'etsopele ea lintho tse bohloko tse amang tsamaiso ea tšilo ea lijo, mokuli o qala ho tletleba ka matšoao a latelang:
- tahlehelo ea takatso ea lijo
- ho se khotsofale ka mpeng
- ho nyekeloa
- botlaela
- tatso e mpe molomong
- lets'ollo
- linako tsa ho hlatsa.
Ho phomola le ho nyekeloa ke pelo ke a mang a litlamorao tsa lithethefatsi tse tsoang ka mpeng.
Hematopoietic litho tsa ka hare
Maemong a sa tloaelehang, batho ba sebelisang moriana ona ba ntše anemia ea megaloblastic. Tabeng ena, tlolo ea molao e bontšoa ke matšoao:
- boikutlo ba ho bata
- setuloana se holofetseng
- ho hloea nama,
- bofokoli bo akaretsang
- paresthesias
- botenya ba maoto le matsoho
- ho se khonehe.
Ho sebelisana le lithethefatsi tse ling
Ha ho kgothaletswe ho kopanya tšebeliso ea nako e le 'ngoe ea formin le meriana e latelang.
- anticoagulants e amanang le litlamorao tsa coumarin - litlamorao tsa lithethefatsi lia fokola,
- phenothiazine, lithethefatsi tse diuretic tsa mofuta oa thiazide, tsoekere, lithibela-pelehi tsa molomo - phello ea karolo e sebetsang ea lithethefatsi e fokotsehile,
- cimetidine - ho tlosoa hoa metformin 'meleng oa mokuli,
- chlorpromazine - kotsi ea hyperglycemia ea eketseha,
- Danazole - phello ea hyperglycemic e matlafalitsoe,
- Li-inhibitors tsa ACE le MAO, tse tsoang ho li-clofibrate le li-NSAIDs - thepa ea keketseho ea Foromo.
Tekanyo ea joala
Ts'ebeliso ea lino tse nang le lino tse tahang e eketsa kotsi ea lactic acidosis.
U lokela ho hana ho noa joala ho qoba nts'etsopele ea lactic acidosis.
Moriana o ka nkeloa sebaka ke li-analogues.
Lisebelisoa tsena ke:
- Glucophage - setlhare sa ho fokotsa hyperglycemia.
- Siofor - setlhare seo e leng sa sehlopha sa Biguanides. E na le phello e ntle ho metabolism ea lipid mme e fokotsa gluconeogenesis.
- Foromo Long ke mofuta o telele oa lithethefatsi o nang le 500, 750, 850 kapa 1000 mg ea ntho e sebetsang.
- Gliformin ke setlhare se reretsoeng ho fokotsa palo ea li-triglycerides le LDL. Lithethefatsi li ka liehisa ts'ebetso ea gluconeogeneis.
- Metformin - sethethefatsi se nang le motsoako o tšoanang, o teng ka tekanyo ea 0,5 kapa 0,85 g.
- Bagomet ke setlhare sa hypoglycemic se etselitsoeng tšebeliso ea molomo.
Siofor le Glukofazh ho tsoa ho lefu la tsoekere le ho theola boima ba 'mele
Lefu la tsoekere, metformin, pono ea lefu la tsoekere | Dr. Butchers
Bopaki ba lingaka le bakuli mabapi le Foromo
Arseny Vladimirov, setsebi sa endocrinologist, ea lilemo tse 54, Moscow
Ts'ebeliso ea FORMETINE ke poloko ho bakuli ba nang le botenya ka lebaka la lefu la tsoekere. Sesebelisoa se nolofalletsa kutloisiso ea litho tsa lisele ho insulin, ntle le ho fana ka tšusumetso e mpe maemong a mokuli. Monyetla o mong ke theko e theko e tlaase.
Valentina Korneva, endocrinologist, ea lilemo li 55, Novosibirsk
Moriana oa sebetsa. Ke e fa bakuli ba ka khafetsa. Ha ho na motho ea tletlebileng ka litlamorao. Mme maemo a fetoha.
Victoria, ea lilemo li 45, Volgograd
Ka thuso ea Foromo, ke boloka boima ba 'mele bo tšoana le bona ka lebaka la lefu la tsoekere, le ile la qala ho ata. Moriana ona o theko e tlaase, o teng Russia. Ke sebelisa moriana ona mantsiboea. Leha ho le joalo, o lokela ho latela lijo, ntle le lijana le lihlahisoa tse nang le lik'hilojule tse ngata.
Dmitry, ea lilemo li 41, Yekaterinburg
Ke qetile nako e telele ke ntse ke phekola lefu lena. Ke bile le lefu la tsoekere lilemo tse fetang 15. Moriana oa thusa, ha o na litla-morao. Ke sebelisa lithethefatsi makhetlo a 2 ka letsatsi bakeng sa letlapa.
Maria, ea lilemo li 56, Saratov
Ke qetile lilemo tse ka bang hlano ke tšoeroe ke lefu la tsoekere. Nako ena eohle Gl Glin o ne a sebelisa, e neng e laetsoe ke ngaka. Setlhare se thusitse, ka hona, ke ne ke tla se sebelisa haholo, empa nakong ea ketelo ea sepetlele ba re ha ho na moriana o joalo.
Forthine e ne e fuoe e le phetoho. Ke ne ke tšaba hore ho fetoha ha meriana ho ka lebisa ho liphetoho tse mpe, empa ho ile ha atleha. Mmele o ne o mamella sethethefatsi sena hantle, kahoo ke ntse ke tsoela pele ho o sebelisa.
Hajoale, batho ba bangata ba na le lefu la tsoekere le botenya ba mofuta o rarahaneng. Ho na le lithethefatsi tse ngata ho phekola maloetse ana. E 'ngoe ea tsona ke moriana oa "Formetin". Mabapi le likarolo tsa eona tsa semelo ho tla tšohloa sehloohong sena.
Tlhaloso ea sebopeho le mofuta oa tokollo
Letlapa le leng le na le:
boima ba kati bo boima ba povidone
Foromo e fumaneha ka har'a lilakane tsa matlapa a 100, 60 kapa 30.
'Mala oa matlapa o tšoeu,' me foromo e latela litekanyetso tsa sehlahisoa sa mantlha. Ho 500 mg, ba na le sebopeho se chitja sa cylindrical se nang le notch le chamfer. Motsoako oa 1000 mg le 850 mg ke "Foromo". Matlapa a ntlheng ena a khaba le oval. Li na le kotsi e le 'ngoe.
Metformin ("Forethine") e fokotsa tsoekere e hlahang ka har'a sebete, ha ho ntse ho na le phokotso ea phepelo ea eona ea glycogen.
Sesebelisoa sena se thusa ho thatafatsa ho monya ha tsoekere e ngata ka mpeng, e ntlafatsa phepelo ea tsoekere tsamaisong ea mali.
Ka nako e ts'oanang, karabelo ea "tisulin" ho "insulin" e eketseha, ntle le ho ama tlhahiso ea karolo ea eona ea endocrine ke manyeme ke lisele tsa B, ka ho fetisa ts'ebetso ea hypoglycemic, kaha tlhahiso ea ntho ena ha e sebetse.
"Formetin" ea lithethefatsi, litlhahlobo tse buang ka ts'ebetso ea eona, e fokotsa palo ea "cholesterol" e mpe le triglycerides maling. lipidrotein tse phahameng ka nako e le 'ngoe li eketseha ka 20-30%.
Ka lijo tse sa sebetseng hantle, "Formetin" ea lithethefatsi, litaelo tseo u ka li sebelisang tse hlalosoang sengoloa sena, li thusa ho fokotsa le ho tiisa boima ba mokuli. Sena se etsahala ka lebaka la oxidation ea tsoekere ka tsela e se nang oksijene, hammoho le ho fokotseha ha takatso ea lijo.
Hape, ts'ebetso ea ts'ebetso ea plasminogen ea lisele e hlahisoa ka ho sebetsa ho inhibitor ea eona, mme ho na le phello e matla.
Ho ea kae-kae
“Mofuta” oa moriana o sebelisetsoa ho phekola mafu a itseng. Ka mantsoe a mang, ho na le lefu la tsoekere la mofuta oa 2, moo ho nang le botenya bo rarahaneng, ha lijo ha li thusa ho boloka boemo ba tsoekere bo tloaelehileng, esita le hammoho le sulfonylurea. Hape e sebetsang ke "Foromo" bakeng sa ho theola boima ba 'mele.
U ka e nka joang?
Ngaka e khetha tekanyetso ea moriana ona ho latela bongata ba tsoekere maling. Tsamaiso ea molomo e lokela ho etsoa ka mor'a lijo, ha u ntse u nooa metsi a mangata ntle le ho pepesetsa letlapa kalafo ea mokhoa.
Joalokaha ho se ho boletsoe ka holimo, litekanyetso li beoa ho latela sethala sa tsoekere e maling. E qala ka bonyane ba 0,5 g kapa 0,85 g ka letsatsi. Matsatsi a mabeli kamora ho qala kalafo ka moriana ona, litaba tse lulang li le teng ka har'a mali li bonoa.
Haeba ho hlokahala, butle-butle u ka eketsa tekanyo ho boleng bo holimo. E lekana le ligrama tse tharo.
Kaha nts'etsopele ea lactic acidosis e bonoa hangata ho batho ba baholo, tekanyo e phahameng ea letsatsi le letsatsi ea litekanyetso ke 1 g bakeng sa bona. Hape, tekanyo ea lithethefatsi e fokotseha haeba ho e-na le ts'usumetso ea metabolic, ho thibela karabelo, e hlahisoang ka mokhoa oa lekhopho la letlalo, le litla-morao tse ling tse tla buisanoa. ka tlase.
Litla-morao
Ho hlaha hoa matšoao a bohloko joalo ka tatso ea "tšepe" molomong, ho hlatsa, ho nyekeloa, lets'ollo, moea, ho hloka takatso ea lijo ho hloka ho emisa ts'ebeliso ea kalafo mme hang-hang ikopanye le setsebi.
Ts'ebeliso ea nako e telele ea lithethefatsi e baka tlolo ea molao kapa ho khaotsa ka botlalo ho vithamine B12, e lebisang ho bokellaneng ha mmele ka morao, ho baka hypovitaminosis. Maemong a sa tloaelehang, ho ba le maemo a fapaneng - khaello ea methapo ea mali e haellang ea B12. Ka tekanyo e fosahetseng, hypoglycemia e ka etsahala. Boitšoaro bo kulang ka tsela ea lekhopho la letlalo le bona bo ka hlaha.
Ka hona, "Foromo" ea lithethefatsi, litekolo tsa eona ka ts'ebeliso ea eona e nepahetseng, li lokela ho fuoa ngaka ea hau feela.
Litekanyetso tsa bohlokoa li khethoa ke ho hlaka ha bokelleke "ntho" ea mantlha 'meleng le litholoana tsa sena.
Ho thibela ho bokellana ha metformin le thibelo ea lactic acidosis, hoa hlokahala ho lekola matšoao a ts'ebetso ea liphio le ho nka liteko ho fumana palo ea lactic acid 'meleng bonyane makhetlo a 2 ka selemo. Hape, ka ponahalo ea bohloko mesifa, ho lokela ho etsoa tlhahlobo ea bobeli.
Matla a sethethefatsi sena ho bokhoni ba ho laola mekgwa le ho khanna makoloi
Tabeng ena, ho boetse ho na le li-nuances tse itseng. Kameho ea "Foromo" ho bokhoni ba ho laola mekhahlelo le lipalangoang e etsahala feela ha e sebelisoa hammoho le lithethefatsi tse amang mekhoa ea ts'ebetso, e hloka karabelo e potlakileng le tlhokomelo e eketsehileng ea tlhokomelo. Sena ke sa bohlokoa ho tseba.
Sebelisa bakeng sa ho anyesa le ho ima
"Mokhoa" oa lithethefatsi, litaelo tsa tšebeliso ea tsona tse hlalosoang temaneng ena, o na le karolo ea ho pepesetsoa "fet" B "ho ea ka FDA". Nakong ea kemolo, sethethefatsi sena se ka nooa. Le ha ho le joalo, ts'ebeliso ea eona e ka ba maemong a itseng feela.
Ka mantsoe a mang, ha sephetho se lebelletsoeng ho tsoa kalafo ena se tla feta boteng ba kotsi e ka bang teng ho lesea. Lithuto tse ling le tse tobileng mabapi le tšebeliso ea lithethefatsi tse kang "Formetin" ea ho lokisa ha lia ka tsa etsoa nakong ea kemaro. Ka nako ea kalafo o lokela ho emisa ho anyesa.
Le ha ho le joalo, o lokela ho batla keletso ea ngaka e tšoanelehang.
"Foromo": analogues
Ho na le lichelete tse ngata tsa mofuta ona. Litšoantšo tsa "Forom" ke litokisetso tse bopiloeng e le karolo ea mantlha ea metformin hydrochloride.
Mohlala ke meriana ea baetsi ba Russia: Vero-Metformin, Glformin, Metformin, Metformin Richter, le ba kantle ho naha - Glucofag, Glucofage le Glucofage Long (France), Langerin "(Slovakia)," Metfogamma "e nang le litekanyetso tse fapaneng tsa sehlahisoa se sebetsang 0.100, 0.500 le 0,850 g (Jeremane).
Theko e tloaelehileng ea "Formetin" ea lithethefatsi e behiloe ho latela litekanyetso: ho tsoa li-ruble tse 59. ka blister 0.5 g, li-ruble tse 133. bakeng sa li-ruble tse 0,85 g le 232. bakeng sa 1 g.
