Glidiab e nkela sebaka: litheko tsa li-analogues le thepa ea lithethefatsi

Setlhare sa hypoglycemic sa molomo se tsoang sehlopheng sa lintho tse tsoang ho sulfonylurea, se fapaneng le lithethefatsi tse tšoanang ka ho ba teng ha reng e nang le heterocyclic ea N e nang le tlamo ea endocyclic.

Gliclazide e fokotsa khatello ea "glucose" e ngata maling, 'me e ntlafatsa secretion ea "insulin" ke li-islets tsa Langerhans. Keketseho ea boemo ba insulin ea postprandial le C-peptide e phehella kamora lilemo tse peli tsa kalafo. Ntle le phello ea metabolism ea carbohydrate, gliclazide e na le litlamorao tsa hemovascular.

Kameho ho secretion ea insulin

Ho mofuta oa 2 lefu la tsoekere, lithethefatsi li khutlisa tlhoko ea pele ea "insulin secretion" ho arabela tšebeliso ea tsoekere le ho matlafatsa karolo ea bobeli ea seculin ea insulin. Keketseho e kholo ea secretion ea insulin e bonoa ho arabela ts'usumetso ka lebaka la ho ja lijo le tsamaiso ea tsoekere.

Glyclazide e fokotsa kotsi ea ts'ebetso ea methapo e fokolang ea mali ts'ebetso e eketsehileng ea activator ea tisy ea plasminogen.

Taolo e matla ea glycemic e thehiloeng ts'ebelisong ea lithethefatsi Diabeteson® MB (glycosylated hemoglobin (HbA1c) lilemo tse 65) - 30 mg (1/2 letlapa) ka letsatsi.

Tabeng ea taolo e lekaneng, sethethefatsi tekanyetso ena se ka sebelisoa bakeng sa kalafo ea tlhokomelo. Ka taolo e sa lekaneng ea glycemic, tekanyetso ea letsatsi le letsatsi ea lithethefatsi e ka eketseha ka tatellano ho isa ho 60 mg, 90 mg kapa 120 mg. Keketseho ea lethal dose e khonahala eseng pele ho khoeli ea 1 ea kalafo ea lithethefatsi ka tekanyetso e boletsoeng esale pele. Mokhelo ke bakuli bao khatello ea bona ea tsoekere ea mali e sa fokotsehang kamora libeke tse peli tsa kalafo. Maemong a joalo, tekanyetso e ka eketseha libeke tse 2 kamora ho qala tsamaiso.

Tekanyo e phahameng ka ho fetisisa e khothalletsoang ea letsatsi le letsatsi ea lithethefatsi ke 120 mg.

Letlapa le le leng le nang le tlhahiso e fetotsoeng (MB) 60 mg e lekana le matlapa a 2 ka tokollo e fetotsoeng 30 mg Ho ba teng ha notch matlapeng a 60 mg ho u fa monyetla oa ho arola letlapa le ho nka tekanyetso ea letsatsi le letsatsi ea 30 mg (1/2 piritsi ea 60 mg), mme ha ho hlokahala 90 mg (1 Letlapa 60 mg le 1/2 piritsi ea 60 mg).

Phetoho ea ho nka lithethefatsi tsa Diabeteson® matlapa a 80 mg ho lithethefatsi tsa Diabeteson® MB litheolelo li lokollotsoe ka 60 mg:

Letlapa le le leng la lithethefatsi Diabeteson® 80 mg le ka nkeloa sebaka ke letlapa le le leng la 2/2 ka tlhahiso e lokisitsoeng ea Diabeton® MB 60 mg. Ha u fetisetsa bakuli ho tloha ho Diabeteson® 80 mg ho Diabeteson® MB, ho khothalletsoa taolo ea glycemic ka hloko.

Phetoho ea ho nka lithethefatsi tse ling tsa hypoglycemic ho li-litafole tsa Diabeton® MB tsa lithethefatsi ka tokollo e fetotsoeng ea 60 mg:

Litafole tsa Diabeteson® MB tsa lithethefatsi tse nang le tlhahiso e fetotsoeng ea 60 mg li ka sebelisoa sebakeng sa moemeli e mong oa hypoglycemic bakeng sa tsamaiso ea molomo. Ha u fetisetsa bakuli ba fumanang lithethefatsi tse ling tsa hypoglycemic bakeng sa tsamaiso ea molomo ho Diabeteson® MB, tekanyetso ea bona le halofo ea bophelo e lokela ho nahanoa. Ha e le molao, nako ea phetoho ha e hlokehe. Tekanyetso ea pele e lokela ho ba 30 mg mme ebe ea kenngoa ka bongata ho latela bongata ba tsoekere ea mali.

Ha Diabeteson® MB e nkeloa sebaka ke lintho tse tsoang ho sulfonylurea nako e telele ea halofo ea bophelo ho qoba hypoglycemia e bakoang ke tšusumetso ea likhahla tse peli tsa hypoglycemic, o ka emisa ho li nka matsatsi a 'maloa. Tekanyetso ea pele ea Diabeteson® MB le eona e na le 30 mg (1/2 kiba 60 mg) mme, haeba ho hlokahala, e ka eketsoa nakong e tlang, joalo ka ha ho hlalositsoe kaholimo.

Ho kopana le sethethefatsi se seng sa hypoglycemic

Diabeteson® MB e ka sebelisoa hammoho le biguanidines, alpha glucosidase inhibitors kapa insulin.

Ka taolo e sa lekaneng ea glycemic, kalafo e eketsehileng ea insulin e lokela ho beoa ka tlhahlobo e hlokolosi ea bongaka.

Lihlopheng tse ikhethang tsa bakuli

Phetoho ea khaba bakeng sa bakuli ba lilemo tse fetang 65 ha e ea hlokahala.

Boithuto ba tsa bongaka bo bontšitse hore phetoho ea lethal dose ho bakuli ba nang le phofshoana ea ho hlaphoheloa ha methapo ha e ea hlokahala. Ho hlahlojoa tlhokomelo ea bongaka e haufi.

Ho bakuli ba kotsing ea ho ba le hypoglycemia (phepo e sa lekaneng kapa e sa leka-lekanang, mathata a endocrine a tebileng kapa a sa sebetseng hantle - ho hloka khaello ea phepo le adrenal, hypothyroidism, ho hlakoloa ha glucocorticosteroids kamora ho tsamaisoa ha nako e telele le / kapa tekanyetso e phahameng, mafu a matla a tsamaiso ea pelo le methapo - lefu le matla la mokokotlo oa mokokotlo, ho ruruha ha methapo ea methapo ea pelo (carotid artery), atherosclerosis e tloaelehileng) ho khothalletsoa ho sebelisa tekanyetso e tlase (30 mg) ea moriana Diabeteson® MB.

Ho fihlella taolo e matla ea glycemic e le ho thibela mathata a lefu la tsoekere, butle-butle u ka eketsa tekanyetso ea Diabeteson® MB ho isa ho 120 mg ka letsatsi ho kenyelletsa le lijo le boikoetliso ho fihlela boemo ba sepheo sa HbA1c. Hopola kotsi ea ho ba le hypoglycemia. Ntle le moo, lithethefatsi tse ling tsa hypoglycemic, mohlala, metformin, alpha-glucosidase inhibitor, thiazolidinedione derivative kapa insulin, li ka eketsoa ho tsa bongaka.

Lintlha tse mabapi le katleho le polokeho ea lithethefatsi ho bana le bacha ba ka tlase ho lilemo tse 18 ha li fumanehe.

Litaelo tsa ho sebelisoa

Glyclazide (sulfonylurea derivative le ntho e nkiloeng ho sulfamide) ke motsoako o ka sehloohong oa ts'ebeliso ea lithethefatsi. E etsa mosebetsi oa hypoglycemic (hypoglycemic).

Tlas'a tšusumetso ea karolo ena, tlhahiso ea insulin ka manyeme le mosebetsi oa enzyme e itseng ea glycogen synthetase ea sebetsa.

Gliclazide e totobatsa boholo ba nako lipakeng tsa ho ja le ho qalella ha mosebetsi o matla oa manyeme ho hlahisa insulin, e fokotsa glycemia ea postprandial (boemo ba tsoekere ka mor'a ho ja).

Ntle le moo, ntho ena e thibela ho khomarela ha lisele tsa mali (li-platelet aggregation), e fokotsa botebo ba methapo ea mali ho li-adrenaline ea li-cell le kotsi ea li-plaque tsa methapo ea methapo ea methapo ea methapo ea methapo.

Lintho tse tlatsetsang lithethefatsi li kenyelletsa: lactose (tsoekere ea lebese), thickener (letsoai la magnesium le stearic acid), talc ea litlhare, cellulose, starch.

Setlhare se kenngoa ka botlalo ke tšilo ea lijo, khatello ea mali maling e bonoa kamora lihora tse 6. Ts'ebetso ea ho tlosa e etsoa ke mala le liphio.

Matšoao le contraindication

Phekolo ea Glidiab e fuoe bakeng sa hyperglycemia e sa foleng ea mofuta oa bobeli (mellitus e sa ts'epheng ea insulin) hammoho le liphetoho tsa phepo.

Contraindication e sebelisitsoeng ke:

Lithethefatsi bakeng sa lefu la tsoekere Forsig le analogues.

• Boemo ba DKA (lefu la tsoekere ketoacidosis),
• hyperglycemia (lefu la tsoekere) la mofuta oa pele,
• Nako ea ho tsoala le ho fepa ngoana,
• a sa tsoeng hantle a renal le hepatic function,
• Ho fokotseha hoa lisele tse tšoeu tsa mali,
• tsoekere e phahameng ea mali le glucose (hyperosmolar coma),
• tshilafalo le mala
• ho se mamelle motho ka mong.

Moriana ha o fuoe bana, bakuli ba nang le ts'ebeliso ea lino tse tahang le maloetse a sa foleng a qoqotho.

Mofuta oa litekanyetso le litekanyetso

Glidiab e hlahisoa ka sebopeho sa lisebelisoa tse 80 mg tsa ntho e sebetsang letlapeng. Pakete e na le likotoana tse 60. Ho boetse ho na le matlapa a nkileng nako e telele a Glidiab MV.

Litekanyetso li baloa ke ngaka ka bonngoe ho mokuli e mong le e mong, ho nahanisisa ka phetoho ea palo ea tsoekere maling maling pele a e ja, le kamora eona. Ka tloaelo, kalafo e qala ka tekanyetso ea letsatsi le letsatsi ea 80-160 mg (320 maximum).

Ho nka moriana ho bontšoa habeli ka letsatsi. Haeba ho hlokahala hore o eketse tekanyetso, nako ea ho fetoha ha tšebeliso ea moriana bonyane libeke tse peli.

Litšobotsi

Phekolo le sethethefatsi e hloka ho hlahlojoa ha maemo a tsoekere letsatsi le letsatsi, hammoho le ho latela lijo tse nang le carb e tlaase. Mabakeng a tlolo ea lijo, ho eketsa ho ikoetlisa, khatello ea maikutlo, ho bohlokoa ho tsebisa ngaka ka sena ho fetola litekanyetso tsa moriana.

Ha li kopantsoe le lino tse nang le joala, matšoao ohle a botahoa a maholo a bonoa (ho hlatsa, ho tsekela, ho opeloa ke hlooho le mala).

Ho fokotseha ha katleho ea phekolo ho baka ho ja ho tšoanang ha li-diuretics le lithibela-pelehi.

Ponahatso ea litla-morao:

• ho ruruha ho feteletseng (hyperhidrosis),
• ho se sebetse hantle ha mesifa (mesifa),
• lebelo la pelo le khutsitseng (bradycardia),
• takatso e matla ea lijo
• tlhokomelo e sitisang
• ho otsela, ho bola, ho se tsotelle,
• ho tšoenyeha ho sa utloahaleng,
• tshilo e bohloko le e thata (dyspepsia),
• setuloana se hlonameng (lets'ollo),
• lefu la tlhaho.

Tekanyetso e feteletseng ea lithethefatsi ha e lumelloe! Hypoglycemic coma e ka hlaha ka lebaka la ho hlokomoloha litaelo tsa bongaka.

Moriana o etsoa Russia ke Akrikhin OJSC. Theko e ka bang li-ruble tse 135.

Glidiab e na le li-analogues tse tšoanang hantle ho latela gliclazide, ho thoe ke lithethefatsi tse tšoanang. Meriana e hlahisoa ke lik'hamphani tse fapa-fapaneng tsa meriana Russia le linaheng tse ling, litšenyehelo tse tloaelehileng tsa ho paka ha li fete li-ruble tse 250.

Li-syonyms tsa Glidiab tse entsoeng Motseng oa Russia: Glyclazide, Glucostabil.

Melemo ea Bohlokoa: Diabeteson (France), Gliclad (Slovenia), Gluktam (France), Diabinaxi Diatika (India), Glioral (Yugoslavia), Diabresid (Italy), Oziklid (Ireland).

Ntle le moo, ho na le lithethefatsi tse tšoanang le Glidiab ts'ebetsong ea hypoglycemic, ntho e sebetsang eo glimepiride e sebetsang ka eona. E etsa mesebetsi e ts'oanang le gliclazide, e bontšoa hore e ka sebelisoa ho hyperglycemia ea mofuta oa bobeli.

Contraindication bakeng sa tse nkang sebaka joalo ha e fapana le Glidiab. Litla-morao li phehella ka mokhoa o feteletseng oa ho ja, ho seng joalo lenane la litlamorao tse sa rateheng le fokotsehile (bradycardia, ho otsela, dyspepsia, ho kulisoa ke letlalo). Therapy e etsoa hammoho le lijo.

Basebeletsi ba antidiabetesic ba Jeremane:

• Amaril. Khampani: Aventis Pharma Deutschland GmbH. Litšenyehelo - 1280 r,
• Maninil. Tlhahiso: Sehlopha sa Berlin-Chemie AG / Menarini. Li-ruble tse 130.

• Glibenclamide. Baetsi ba Akrikhin HFK, ALSI Pharma, Antiviral, Bivitech, Biosynthesis. Theko e ka bang li-ruble tse 200.
• Glimepiride. E hlahisoa ke likhamphani tsa Vertex, tsa Pharmstandard-Leksredstva. Litsenyehelo ke li-ruble tse190.

Ho boetse ho na le bo-Amik ba Czech. Production Zentiva, ka theko ea li-ruble tse 670, le mofuta oa Greece oa Glyurenorm. Moetsi: BoehringerIngelheimEllas, ka theko ea 450 p.

Tabeng ea ts'ebetso ea bongaka e hlokahalang, ho hlokahala hore u tsebise ngaka ka kalafo le Glidiab kapa li-analogues tsa eona, kaha ho khethoa ha lithethefatsi tsa insulin ha ho khetholloe.

Litlhahlobo tsa Phetoho ea Glidiab

Mofuta oa 2 oa lefu la tsoekere ha se polelo. Ke se ke qetile lilemo tse 'maloa ke sebelisa Glidiab, e leng se thusang ho boloka tsoekere ea mali e tlas'a taolo.. Ho rekisitsoe, ehlile, ho na le lisebelisoa tsa sejoale-joale, empa li theko e boima ho feta. Setlhare sa ka ha se theko e phahameng ebile sea sebetsa.

Ka lebaka la kalafo e fosahetseng ea e 'ngoe ea maloetse, tsoekere e ile ea qala ho hlaha ho nna. Ka lebaka leo, ts'oaetso ke lefu la tsoekere la mofuta oa 2. Ngaka e laetse Glutenorm. Ke ile ka e amohela ka botšepehi, 'me ka ikutloa ke atlehile. Empa moriana o tlameha ho nooa o sa khaotse, empa o bitsa haholo. Ka likeletso, o ile a nkela Glidiab sebaka. Liphetho lia tšoana, empa theko e tlase makhetlo a mararo.

Ntate-moholo o bile le lefu la tsoekere nako e telele. O fuoa lefu la tsoekere, leo ke lulang ke le reka. Bakeng sa lekhetlo la ho qetela, ho ne ho se na Diabeteson pharmacy. Rak'hemiste o laetse ho nkela Glidiab sebaka. Ke sa tsoa reka sephutheloana. Ho latela maikutlo, moriana o fokotsa maemo a tsoekere hantle, ka litsela tsohle a loketse kalafo.

Li-analog tsa Glidiab

Analog e theko e phahameng haholo ho tsoa ho li-ruble tse 8.

Gliclazide MV ke litokisetso tsa letlapa bakeng sa kalafo ea mofuta oa 2 lefu la tsoekere le thehiloeng ka karolo e le 'ngoe e sebetsang litekanyetsong tsa 30 mg. E fuoa mokhoa oa ho ja hantle le ho ikoetlisa. Gliclazide MV e hanyetsanoa ho bakuli ba nang le lefu la tsoekere la mofuta oa 1 (ba itšetlehileng ka insulin).

Analog e theko e phahameng haholo ho tsoa ho li-ruble tse 10.

Akrikhin (Russia) Glidiab ke e 'ngoe ea tse molemo ka ho fetisisa tse nkang sebaka sa gliclazide. E fumaneha hape ka sebopeho sa letlapa, empa litekanyetso tsa DV li phahame mona, tse lokelang ho tsotelloa pele ho qala kalafo. Ho bontšoa mofuta oa lefu la tsoekere la mofuta oa 2 o nang le lijo tse sa sebetseng le ho ikoetlisa.

Analogue e theko e phahameng haholo ho tloha ho li-ruble tse 168.

Litokisetso tsa letlapa la Russia bakeng sa kalafo ea lefu la tsoekere. Lintho tse sebetsang: gliclazide e le tekanyetso ea 60 mg ka ho pilisi. E bontšoa kalafo ea lefu la tsoekere la mofuta oa 2 le sepheo sa prophylactic.

Analogue e theko e phahameng haholo ho tsoa ho li-ruble tse 72.

Moetsi: Pharmstandard (Russia)
Liforomo tsa ho Lokolla:

• Tab. 2 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 191
• Tab. 3 mg, li-pcs tse 30.. Theko e tsoang ho li-ruble tse 272

Litheko tsa Glimepiride ka litlhare tsa marang-rang
Litaelo tsa ho sebelisoa

Glimepiride ke setlhare sa lapeng ho phekoloa lefu la tsoekere la mofuta oa 2. E fumaneha ka mokhoa oa matlapa a nang le ntho e le 'ngoe e sebetsang ka litekanyetso tsa 2 ho isa ho 4 mg ka ho pepa.

Analog e theko e phahameng haholo ho tsoa ho li-ruble tse 9.

Moetsi: E ntse e hlakisoa
Liforomo tsa ho Lokolla:

• Tab. le MV 30 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 128
• Tab. 3 mg, li-pcs tse 30.. Theko e tsoang ho li-ruble tse 272

Litheko tsa Diabetesalong ka litlhare tsa marang-rang
Litaelo tsa ho sebelisoa

Diabetesalong ke lithethefatsi tsa matlapa bakeng sa kalafo ea mofuta oa 2 mellitus o thehiloeng gliclazide ka bongata ba 30 mg. Moriana o fanoe ka katleho e sa lekanang ea ho ikoetlisa le ho ja. Ho na le li-contraindication le litla-morao.

Analogue e theko e tlase ho tsoa li-ruble tse 73.

Moetsi: Valenta (Russia)
Liforomo tsa ho Lokolla:

• Matlapa a 5 mg, li-pcs tse 50, theko e tsoang ho li-ruble tse 46
• Tab. 3 mg, li-pcs tse 30.. Theko e tsoang ho li-ruble tse 272

Litheko tsa Glibenclamide ka litlhare tsa marang-rang
Litaelo tsa ho sebelisoa

Glibenclamide ke lithethefatsi tse theko e tlaase haholo tsa Russia bakeng sa kalafo ea lefu la tsoekere le motsoako o tšoanang o sebetsang tlatsong. Litekanyetso li itšetleha ka lilemo tsa mokuli le ho teba ha kalafo ho lefu la tsoekere.

Analog e theko e phahameng haholo ho tloha li-ruble tse 190.

Moetsi: Sanofi-Aventis S.p.A. (Itali)
Liforomo tsa ho Lokolla:

• Tab. 1 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 309
• Tab. 2 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 539

Litheko tsa Amaryl ka litlhare tsa marang-rang
Litaelo tsa ho sebelisoa

Amaryl ke kalafo bakeng sa lefu la tsoekere la mofuta oa 2 ka mofuta oa litafole tse reretsoeng ho sebelisoa kahare. Joaloka ntho e sebetsang, glimepiride e sebelisoa ka tekanyetso ea 1 ho isa ho 4 mg. Ho na le li-contraindication le litla-morao.

Analog e theko e phahameng haholo ho tsoa ho li-ruble tse 20.

Moetsi: Berlin-Chemie / Menarini Pharma (Jeremane)
Liforomo tsa ho Lokolla:

• Matlapa a 5 mg, li-pcs tse 120., Theko e tsoang ho li-ruble tse 139
• Tab. 2 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 539

Litheko tsa Maninil 5 libakeng tsa litlama tsa marang-rang
Litaelo tsa ho sebelisoa

Letlhare la litlhare bakeng sa kalafo ea lefu la tsoekere le thehiloeng ho glibenclamide (ka sebopeho sa micron) ka litekanyetso tsa 1,75 mg. Ho bonts'oa ts'ebeliso ea mofuta oa 2 lefu la tsoekere (ka ho se sebetse hantle ha lijo tse thata).

Analogue e theko e phahameng haholo ho tsoa ho li-ruble tse 67.

Moetsi: Canonpharma (Russia)
Liforomo tsa ho Lokolla:

• Tab. 2 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 186
• Tab. 4 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 252

Litheko tsa Canon glimepiride ka litlhare tsa marang-rang
Litaelo tsa ho sebelisoa

Glimepiride Canon ke e 'ngoe ea lithethefatsi tse molemo haholo bakeng sa kalafo ea mofuta oa 2 lefu la tsoekere e thehiloeng ho glimepiride ka tekanyo e ts'oanang. E laetsoe ho se sebetse hantle ha lijo le ho ikoetlisa.

Analogue e theko e phahameng haholo ho tsoa ho li-ruble tse 91.

Moetsi: Akrikhin (Russia)
Liforomo tsa ho Lokolla:

• Tab. 1 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 210
• Tab. 2 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 319

Litheko tsa Diameride ka litlhare tsa inthanete
Litaelo tsa ho sebelisoa

Canonpharma (Russia) Glimepiride Canon ke e 'ngoe ea lithethefatsi tse molemo haholo bakeng sa ho phekoloa lefu la tsoekere la mofuta oa 2 le thehiloeng ho glimepiride ka tekanyo e ts'oanang. E laetsoe ho se sebetse hantle ha lijo le ho ikoetlisa.

Analogue e theko e phahameng haholo ho tloha ho li-ruble tse 183.

Moetsi: Krka (Slovenia)
Liforomo tsa ho Lokolla:

• Matlapa a 60 mg, li-pcs tse 30., Theko ho tloha li-ruble tse 302
• Tab. 2 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 319

Litheko tsa Gliclada ka litlhare tsa marang-rang
Litaelo tsa ho sebelisoa

Litokisetso tsa letlapa la Slovenia bakeng sa kalafo ea lefu la tsoekere la mofuta oa 2. Joalo ka ntho e sebetsang, gliclazide e sebelisoa ho litekanyetso li 30 kapa 60 mg ka ho pepa. Ho na le li-contraindication le litlamorao tse ka bang teng.

Analogue e theko e phahameng haholo ho tloha ho li-ruble tse 277.

Moetsi: Beringer Ingelheim International GmbH (Jeremane)
Liforomo tsa ho Lokolla:

• Tab. 30 mg, li-pcs tse 60., Theko e tsoang ho li-ruble tse 396
• Tab. 2 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 319

Litheko tsa glurenorm ka litlhare tsa marang-rang
Litaelo tsa ho sebelisoa

Glurenorm ke litokisetso tsa letlapa bakeng sa kalafo ea mofuta oa 2 lefu la tsoekere le thehiloeng glycidone ho litekanyetso tsa 30 mg. E na le khokahano ea mofuta oa 1 lefu la tsoekere, ho nyeka, ho ima, lefu la sebete le liphio. Lenane le felletseng la li-contraindication le ka fumanoa litaelong.

Li-analog mabapi le sebopeho le pontšo ea ts'ebeliso

Sehlooho	Theko ho la Russia	Theko Ukraine
Bisogamma Glyclazide	91 rub	182 UAH
Diabeteson MR	--	92 UAH
Diagnizide mr Gliclazide	--	15 UAH
Glidia MV Gliclazide	--	--
Glykinorm Gliclazide	--	--
Gliclazide Gliclazide	231 rub	57 UAH
Glyclazide 30 MV-Indar Glyclazide	--	--
Glyclazide-Health Gliclazide	--	36 UAH
Glioral Glyclazide	--	--
Lekola Gliclazide	--	14 UAH
Diazide MV Gliclazide	--	46 UAH
Osliklid Gliclazide	--	68 UAH
Diadeon gliclazide	--	--
Glyclazide MV Gliclazide	4 rub	--

Lethathamo le ka holimo la li-analogues tsa lithethefatsi, tse bonts'ang Mahlatse a Glidiab, e loketse haholo hobane e na le sebopeho se tšoanang sa lintho tse sebetsang ebile e lumellana ho latela sesupo sa tšebeliso

Li-analoggs ka pontšo le mokhoa oa ts'ebeliso

Sehlooho	Theko ho la Russia	Theko Ukraine
Glibenclamide Glibenclamide	30 rub	7 UAH
Maninyl Glibenclamide	54 rub	37 UAH
Glibenclamide-Health Glibenclamide	--	12 UAH
Glyurenorm glycidone	94 rub	43 UAH
Amaril	27 rub	4 UAH
Glemaz glimepiride	--	--
Glian glimepiride	--	77 UAH
Glimepiride Glyride	--	149 UAH
Glimepiride diapiride	--	23 UAH
Aletare	--	12 UAH
Glimax glimepiride	--	35 UAH
Glimepiride-Lugal glimepiride	--	69 UAH
Clay glimepiride	--	66 UAH
Diabrex glimepiride	--	142 UAH
Meglimide glimepiride	--	--
Melpamide Glimepiride	--	84 UAH
Perinel glimepiride	--	--
Glempid	--	--
Ke thabo	--	--
Glimepiride glimepiride	27 rub	42 UAH
Glimepiride-teva glimepiride	--	57 UAH
Glimepiride Canon glimepiride	50 rub	--
Glimepiride Pharmacyard glimepiride	--	--
Dimaril glimepiride	--	21 UAH
Glamepiride diamerid	2 rub	--

Moetso o fapaneng o kanna oa lumellana ho bonts'a mokhoa le mokhoa oa ts'ebeliso

Sehlooho	Theko ho la Russia	Theko Ukraine
Rosiglitazone e sebetsang, metformin hydrochloride	--	--
Bagomet Metformin	--	30 UAH
Glucofage metformin	12 rub	15 UAH
Glucophage xr metformin	--	50 UAH
Reduxin Met Metformin, Sibutramine	20 rub	--
Dianormet	--	19 UAH
Diaformin metformin	--	5 UAH
Metformin metformin	13 rub	12 UAH
Metformin sandoz metformin	--	13 UAH
Siofor	208 rub	27 UAH
Foromo metformin hydrochloride	--	--
Emnorm EP Metformin	--	--
Megifort Metformin	--	15 UAH
Metamine Metformin	--	20 UAH
Metamine SR Metformin	--	20 UAH
Metfogamma metformin	256 rub	17 UAH
Tefor metformin	--	--
Glycometer	--	--
Glycomet SR	--	--
Forthine	37 rub	--
Metformin Canon metformin, ovidone K 90, starch ea poone, crospovidone, magnesium stearate, talc	26 rub	--
Insuffor metformin hydrochloride	--	25 UAH
Metformin-teva metformin	43 rub	22 UAH
Diaformin SR metformin	--	18 UAH
Mepharmil Metformin	--	13 UAH
Metformin Farmland Metformin	--	--
Amaryl M Limepiride Micronized, Metformin Hydrochloride	856 rub	40 UAH
Glibomet glibenclamide, metformin	257 rub	101 UAH
Glucovans glibenclamide, metformin	34 rub	8 UAH
Dianorm-m Glyclazide, Metformin	--	115 UAH
Dibizid-m glipizide, metformin	--	30 UAH
Douglimax glimepiride, metformin	--	44 UAH
Duotrol glibenclamide, metformin	--	--
Gluconorm	45 rub	--
Glibofor metformin hydrochloride, glibenclamide	--	16 UAH
Avandamet	--	--
Avandaglim	--	--
Janumet metformin, sitagliptin	9 rub	1 UAH
Velmetia metformin, sitagliptin	6026 rub	--
Galvus Met vildagliptin, metformin	259 rub	1195 UAH
Tripride glimepiride, metformin, pioglitazone	--	83 UAH
Comboglize XR metformin, saxagliptin	--	424 UAH
Comboglyz Prolong metformin, saxagliptin	130 rub	--
Gentadueto linagliptin, metformin	--	--
Vipdomet metformin, alogliptin	55 rub	1750 UAH
Sinjardi empagliflozin, metformin hydrochloride	240 rub	--
Voglibose Oxide	--	21 UAH
Glutazone pioglitazone	--	66 UAH
Dropia Sanovel pioglitazone	--	--
Januvia sitagliptin	1369 rub	277 UAH
Galvus vildagliptin	245 rub	895 UAH
Onglisa saxagliptin	1472 rub	48 UAH
Nesina alogliptin	--	--
Vipidia alogliptin	350 rub	1250 UAH
Trazhenta linagliptin	89 rub	1434 UAH
Lixumia lixisenatide	--	2498 UAH
Sebaka sa Guarem Guar	9950 rub	24 UAH
Insvada repaglinide	--	--
Novonorm Repaglinide	30 rub	90 UAH
Repodiab Repaglinide	--	--
Baeta Exenatide	150 rub	4600 UAH
Baeta Long Exenatide	10248 rub	--
Viktoza liraglutide	8823 rub	2900 UAH
Saxenda liraglutide	1374 rub	13773 UAH
Forksiga Dapagliflozin	--	18 UAH
Forsiga Dapagliflozin	12 rub	3200 UAH
Invocana canagliflozin	13 rub	3200 UAH
Jardins Empagliflozin	222 rub	566 UAH
Trulicity Dulaglutide	115 rub	--

U ka fumana analogue e theko e tlaase ea moriana o theko e phahameng?

Ho fumana analogue e theko e phahameng ea moriana, mofuta o tšoanang kapa oa mantsoe, pele ho tsohle re khothaletsa ho ela hloko sebopeho, e leng lintho le lipontšo tse tšoanang tse sebetsang. Metsoako e tšoanang ea lithethefatsi e tla bonts'a hore lithethefatsi li tsamaisana le lithethefatsi, li ka lekana meriana kapa li ka etsa meriana. Leha ho le joalo, u se ke oa lebala ka likarolo tse sa sebetseng tsa lithethefatsi tse tšoanang, tse ka amang polokeho le ts'ebetso. Se ke la lebala ka litaelo tsa lingaka, ho itlama ho ka lematsa bophelo ba hau, ka hona, etela ngaka ea hau kamehla pele u sebelisa meriana leha e le efe.

Litla-morao

Ha ho fanoa ka boiphihlelo ka gliclazide le tse ling tse tsoang ho sulfonylurea, litlamorao tse latelang li lokela ho tsotelloa.

Joalo ka lithethefatsi tse ling tsa sulfonylurea, Diabeteson® MB e ka baka hypoglycemia haeba ho ka jeoa khafetsa, haholo ha lijo li sa tlotsoe. Matšoao a ka bang teng a hypoglycemia: hlooho e opang, tlala e matla, ho nyekeloa, ho felloa ke matla, ho tšoenyeha ka boroko, ho teneha, ho fokotseha ha tlhokomelo, ho lieha ho arabela, khatello ea maikutlo, pherekano, pono e fifalitsoeng le puo, aphasia, ho thothomela, pherese, kutloisiso e senyehileng. , ho tsekela, ho fokola, ho tsitsipana, bradycardia, delirium, ho hloleha ho phefumoloha, ho otsela, ho lahleheloa ke kelello ka tsoelo-pele ea lefu la ho akheha, ho fihlela lefung.

Boitšoaro ba Andrenergic bo ka boela ba hlokomeleha: mofufutso o eketsehileng, letlalo la "clammy", ho tšoenyeha, tachycardia, khatello ea mali ea methapo, ho phahamisa mahlo, ho hlasimoloha, le angina pectoris.

Ha e le molao, matšoao a hypoglycemia a emisoa ka ho nka limatlafatsi (tsoekere). Ho nka li-sweeteners ha ho na thuso. Khahlano le semelo sa tse ling tse tlisoang ke sulfonylurea, liphapang tsa hypoglycemia li ile tsa lemohuoa kamora phomolo e atlehileng.

Ho hypoglycemia e matla kapa ea nako e telele, ho bontšoa tlhokomelo ea bongaka ea tšohanyetso, mohlomong ka ho kena sepetlele, le haeba ho e-na le phello ea ho nka lik'habohaedreite.

Litla-morao tse ling

Ho tsoa ho tsamaiso ea tšilo ea lijo: ho opeloa ke mpa, ho nyekeloa ke pelo, ho hlatsa, lets'ollo, ho sokela. Ho nwa moriana nakong ea lijo tsa hoseng ho qoba matšoao ana kapa ho a fokotsa.

Litlamorao tse latelang ha li sa tloaeleha:

Karolong ea letlalo le lisele tse potolohileng: lekhopho, ho hlohlona, ​​urticaria, erythema, lekhopho la maculopapular, lekhopho le matla.

Ho tsoa ho sistimi ea hemopoietic: mathata a hematological (anemia, leukopenia, thrombocytopenia, granulocytopenia) ha a na seoelo. Joaloka molao, liketsahalo tsena lia fetoha haeba phekolo e khaotsa.

Karolong ea sebete le pampiri ea biliary: ts'ebetso e eketsehileng ea hepatic enzymes (AST, ALT, alkaline phosphatase) maemong a sa tloaelehang - hepatitis. Haeba choleundatic jaundice e etsahala, phekolo e lokela ho khaotsa.

Litlamorao tse latelang li atisa ho fetoha ha phekolo e khaotsa.

Ho tloha lehlakoreng la setho sa pono: Litšitiso tse sa feleng tsa pono li ka hlaha ka lebaka la phetoho ea maemo a tsoekere ea mali, haholoholo qalong ea kalafo.

Litla-morao tse hlahisoang ke sulfonylurea derivatives li tlalehiloe maemong a erythrocytopenia, agranulocytosis, hemolytic anemia, pancytopenia le alculgic vasculitis. Hape, ha re ntse re nka li-derivatives tse ling tsa sulfonylurea, keketseho ea tšebetso ea li-enzyme tsa sebete, ho sitisoa ha ts'ebetso ea sebete (mohlala, ka nts'etsopele ea cholestasis le jaundice) le hepatitis li ile tsa hlokomeloa. Lipontšo tsena li ile tsa fokotseha ha nako e ntse e tsamaea kamora ho khaotsa litokisetso tsa sulfonylurea, empa maemong a mang ho ile ha fella ka hore bophelo ba sebete bo se ke ba atleha.

Litla-morao tse lemohileng litekong tsa bongaka

Phuputsong ea ADVANCE, ho bile le phapang e nyane khafetsa ea liketsahalo tse mpe tse mpe tse mpe lipakeng tsa lihlopha tsena tse peli tsa bakuli. Ha ho lintlha tse ncha tsa polokeho tse fumanoeng. Palo e fokolang ea bakuli e ne e e-na le hypoglycemia e matla, empa kakaretso ea hypoglycemia e ne e le tlase. Kotsi ea hypoglycemia sehlopheng se matla sa taolo ea glycemic e ne e phahame ho feta sehlopheng se laoloang ke glycemic. Likarolo tse ngata tsa hypoglycemia sehlopheng se matla sa taolo ea glycemic li ile tsa bonoa khahlano le semelo sa phekolo ea insulin.

Contraindication mabapi le ts'ebeliso ea lithethefatsi DIABETON® MV

• mofuta oa 1 lefu la tsoekere
• lefu la tsoekere ketoacidosis, lefu la tsoekere, lefu la tsoekere,
• a renal e matla kapa a haelloa ke hepatic (maemong ana, ho khothalletsoa ho sebelisa insulin),
• Tšebeliso e tšoanang ea miconazole,
• boimana
• lactation (matsoele),
• lilemo tse 18
• hypersensitivity ho gliclazide kapa mang kapa mang ea fumanang lithethefatsi, sulfonylureas tse ling, sulfonamides.

Ka lebaka la hore litokisetso li na le lactose, Diabeton® MB ha e khothalletsoe ho bakuli ba nang le ts'oarelo ea lactose ts'oarello, galactosemia, glucose / galactose malabsorption syndrome.

Ha ho khothalletsoe ho sebelisa lithethefatsi hammoho le phenylbutazone kapa danazole.

Ka hloko, lithethefatsi li lokela ho sebelisoa ka phepo e sa lekanyetsoang le / kapa e sa leka-lekanang, khaello ea glucose-6-phosphate dehydrogenase, mafu a matla a tsamaiso ea methapo ea pelo, hypothyroidism, adrenal kapa pituitary insuffence, renal le / kapa ho hloleha ha sebete, kalafo ea nako e telele ka li-corticosteroids, botahoa, bakuli ba tsofetseng. lilemo.

Ts'ebeliso ea lithethefatsi DIABETON® MV nakong ea bokhachane le pelehi

Ha ho na boiphihlelo ka gliclazide nakong ea kemolo. Lintlha tse mabapi le tšebeliso ea tse ling tse fumanoeng sulfonylurea moimana li na le moeli.

Boithutong ba liphoofolo tse sebelisoang ka laboratoring, litla-morao tsa "gliclazide" ha li so tsejoe.

Ho fokotsa kotsi ea tšoaetso ea tlhaho ea tlhaho, ho hlokahala hore ho laoloe hantle (kalafo e nepahetseng) ea lefu la tsoekere.

Lithethefatsi tsa molomo tsa molomo nakong ea kemolo ha li sebelisoe. Insulin ke lithethefatsi tsa khetho bakeng sa kalafo ea lefu la tsoekere ho basali baimana. Ho khothalletsoa ho nka sebaka sa ts'ebeliso ea lithethefatsi tsa molomo tsa hypoglycemic ka kalafo ea insulin ka bobeli nakong ea kemaro e reriloeng, le hore na ho ima ho etsahetse ha u ntse u sebelisa moriana.

Ka ho nahana ka ho haella ha tlhaiso-leseling mabapi le tšebeliso ea gliclazide ka lebese la matsoele le kotsi ea ho ba le neonatal hypoglycemia, letsoele le hanyetsoa nakong ea kalafo ea lithethefatsi.

Litaelo tse khethehileng

Ha ho fana ka tlhahiso ea lefu la tsoekere la Diabeteson, ho lokela ho hopoloa hore hypoglycemia e ka hlaha ka lebaka la ho nka lintho tse tsoang ho sulfonylurea, 'me maemong a mang e le ka sebopeho se matla le sa nako e telele, se hlokang ho kenngoa sepetlele le tsamaiso ea dextrose (glucose) ka matsatsi a' maloa.

Setlhare se ka fuoa feela bakuli bao lijo tsa bona li leng teng khafetsa 'me li kenyelletsa lijo tsa hoseng. Ho bohlokoa haholo ho boloka tšebeliso e lekaneng ea lik'habohaedreite ka lijo, joalo ka kotsi ea ho ba le hypoglycemia e eketseha ka khaello ea phepo e nepahetseng kapa khaello ea phepo e nepahetseng, hammoho le tšebeliso ea lijo tse haelloang ke lik'habohaedreite. Hypoglycemia hangata e hlaha ka ho ja lijo tse nang le khalori e tlase, ka mor'a ho ikoetlisa ka nako e telele kapa ka matla, ka mor'a ho noa joala, kapa ha u sebelisa lithethefatsi tse 'maloa tsa hypoglycemic ka nako e le' ngoe.

Ka tloaelo, matšoao a hypoglycemia a nyamela kamora ho ja lijo tse nang le lik'habohaedreite tse ngata (tse kang tsoekere). Re lokela ho hopola hore ho nka li-sweeteners ha ho thusa ho tlosa matšoao a hypoglycemic. Phihlelo ea ho sebelisa litlatsetso tse ling tsa sulfonylurea e fana ka maikutlo a hore hypoglycemia e ka khutla le ha boemo bona bo ka ba bonolo. Haeba matšoao a hypoglycemic a boletsoe kapa e le a nako e telele, le maemong a ntlafatso ea nakoana kamora ho ja lijo tse nang le lik'habohaedreite, ho hlokahala tlhokomelo ea tšohanyetso ea bongaka, ho fihlela sepetlele.

Ho qoba nts'etsopele ea hypoglycemia, ho hlokahala hore motho a khethe lithethefatsi le mofuta oa kalafo ka hloko hammoho le ho fa mokuli tlhaiso-leseling e felletseng ka kalafo e boletsoeng.

Kotsi e eketsehileng ea hypoglycemia e ka hlaha maemong a latelang:

• ho hana kapa ho se khonehe ha mokuli (haholo-holo batho ba baholo) ho latela litaelo tsa ngaka le ho hlokomela boemo ba hae,
• phepo e sa lekaneng le e sa sebetseng, ho tlōla lijo, ho itima lijo le ho fetola lijo,
• ho se lekane pakeng tsa ts'ebetso ea 'mele le palo ea lik'habohaedreite tse nkiloeng,
• ho hloleha ha rems
• ho hloleha ho matla ha sebete
• overdose of the drug Khaba Khweib,
• maloetse a mang a endocrine (lefu la qoqotho, ho hloka pituara le ho hlokeha ha tlhaho),
• tšebeliso e tšoanang ea lithethefatsi tse ling.

Hepatic / Ho hloloa hoa letsoai hape

Bakeng sa bakuli ba nang le bothata bo matla ba hepatic le / kapa renal, ho na le phetoho mokhoeng oa pharmacokinetic le / kapa oa pharmacodynamic oa gliclazide. Hypoglycemia e hlahang ho bakuli bana e ka ba telele haholo, maemong a joalo, ho hlokahala kalafo e loketseng hanghang.

Tlhahisoleseling ea mokuli

Hoa hlokahala ho tsebisa mokuli le litho tsa lelapa la hae ka kotsi ea ho ba le hypoglycemia, matšoao a eona le maemo a tsamaisanang le kholo ea eona. Mokuli o tlameha ho tsebisoa ka likotsi le melemo ea kalafo e boletsoeng. Mokuli o hloka ho hlakisa bohlokoa ba ho ja, tlhoko ea ho ikoetlisa khafetsa le ho lekola maemo a tsoekere ea mali kamehla.

Taolo e sa lekanang ea glycemic

Taolo ea glycemic ho bakuli ba fumanang kalafo ea hypoglycemic e kanna ea fokola maemong a latelang: feberu, ho sithabela maikutlo, lefu le tšoaetsanoang, kapa ho buuoa ho hoholo. Maemong ana, ho kanna ha hlokahala hore o khaotse ho phekoloa ka Diabeteson® MB le ho fana ka kalafo ea insulin.

Ho bakuli ba bangata, ho sebetsa ha li-hypoglycemic agents ho kenyeletsa gliclazide, e sekhahla ka mor'a nako e telele ea kalafo. Tšusumetso ena e ka bakoa ke ho tsoela pele ha lefu lena le ho fokotseha ha karabelo ea kalafo ho moriana. Ketsahalo ena e tsejoa e le ho hanyetsa lithethefatsi tsa bobeli, tse lokelang ho khetholloa ho ea mantlha, moo moriana o sa feng phello e lebelletsoeng ea kliniki nakong ea kopano ea pele. Pele o tseba mokuli ka khatello ea bobeli ea lithethefatsi, ho hlokahala hore ho hlahlojoe ho lekana ha khetho ea lethal dose le ho lumellana le mokuli ka lijo tse boletsoeng.

Tlhokomelo ea laboratori

Ho hlahloba taolo ea glycemic, ho khothalletsoa boikemisetso ba ho pepela lijo tsa glucose le glycosylated hemoglobin. Ntle le moo, ho bohlokoa hore nako le nako u itlhahlobe ho tsepamisang mahlo tsoekere ea mali.

Lintho tse tsoang ho Sulfonylurea li ka baka anemia ea hemolytic ho bakuli ba nang le khaello ea glucose-6-phosphate dehydrogenase. Kaha gliclazide ke sulfonylurea e tsoang ho eona, tlhokomelo e lokela ho nkuoa ha e e fuoa ho bakuli ba nang le khaello ea glucose-6-phosphate dehydrogenase. Monyetla oa ho hlahisa moriana oa hypoglycemic oa sehlopha se seng o lokela ho hlahlojoa.

Bongata

Haeba ho na le lithethefatsi tse ngata tse tsoang ho sulfonylurea, ho ka hlaha hypoglycemia.

Phekolo: haeba matšoao a hypoglycemia a itekanetse a hlaha, o lokela ho eketsa tekanyo ea lik'habohaedreite ka lijo, fokotsa tekanyo ea lithethefatsi le / kapa ho fetola lijo. Ho lekola ka hloko boemo ba mokuli ho lokela ho tsoelapele ho fihlela ngaka e eang e netefatsa hore bophelo ba mokuli ha bo kotsing.

Mohlomong nts'etsopele ea maemo a matla a hypoglycemic, e tsamaeang le komisi, ho akheha kapa mathata a mang a methapo ea methapo. Haeba matšoao a joalo a hlaha, ho hlokahala tlhokomelo ea tšohanyetso ea bongaka le ho kena sepetlele hang-hang.

Haeba coma ea hypoglycemic e belaelloa kapa e fumanoa, mokuli o kenngoa kahare kahare ka 50 ml ea tharollo ea 20-30% dextrose (glucose). Ebe iv e akhela tharollo ea 10% ea dextrose (tsoekere) ho boloka tsoekere e maling maling a kaholimo ho 1 g / L. Ho lekola ka hloko ho lokela ho etsoa bonyane nakong ea lihora tse 48 tse tlang. Nakong e tlang, ho latela boemo ba mokuli, potso ea tlhokeho ea ho lekola mesebetsi ea bohlokoa ea mokuli e lokela ho etsoa qeto.

Ho buoa ka methapo ha ho na thuso ka lebaka la ho tlangoa ha gliclazide liprotheine tsa plasma.

Ho sebelisana le lithethefatsi

Lithethefatsi tse eketsang litlamorao tsa Diabeteson MB (eketsa kotsi ea hypoglycemia)

Motsoako o kopantsoeng

Ts'ebeliso e tšoanang ka miconazole (bakeng sa ts'ebeliso ea mokhoa le ha o sebelisa li-gel ka hanong la molomo) e lebisa ho eketsong ea phello ea hypoglycemic ea glycazide (hypoglycemia e ka nyolohela ho komisi).

Ha e khothalletsoe motsoako

Phenylbutazone (bakeng sa ts'ebeliso ea ts'ebetso) e ntlafatsa phello ea hypoglycemic ea litokollo tsa sulfonylurea, joalo ka e ba tlosa khokahanong le liprotheine tsa plasma le / kapa e liehisa ho tsoa hoa 'mele oa bona. Ho molemo ho sebelisa sethethefatsi se seng se thibelang mafu. Haeba phenylbutazone e hlokahala, mokuli o lokela ho lemosoa ka tlhokahalo ea taolo ea glycemic. Haeba ho hlokahala, tekanyetso ea lithethefatsi Diabeteson® MB e lokela ho fetoloa ha o ntse o nka phenylbutazone le ka mor'a eona.

Ka tšebeliso ea nako e le 'ngoe le lithethefatsi Diabeteson® MB, ethanol e ntlafatsa hypoglycemia, e thibela mekhabiso, mme e ka kenya letsoho kholisong ea komello ea hypoglycemic. Hoa hlokahala ho hana ho nka meriana, e kenyelletsang ethanol le ho se noe joala.

Litlhokomelo tse khethehileng

Gliclazide hammoho le meriana e meng (mohlala, li-agents tse ling tsa hypoglycemic - insulin, acarbose, biguanides, beta-blockers, fluconazole, ACE inhibitors - Captopril, enalapril, histamine H2 receptor blockers, MAO inhibitors, sulfanilam) phello le kotsi ea hypoglycemia.

Lithethefatsi tse fokotsang phello ea Diabeteson MV (eketsa tsoekere ea mali)

Ha e khothalletsoe motsoako

Danazole o na le lefu la tsoekere. Haeba ho sebelisa lithethefatsi tsena hoa hlokahala, mokuli o khothalletsoa ho laola taolo ea glycemic ka hloko. Haeba ho hlokahala hore ho sebelisoe lithethefatsi hammoho, ho khothalletsoa hore tekanyetso ea moemeli oa hypoglycemic e khethoe ka bobeli nakong ea ho nka danazol le kamora ho hlakoloa.

Litlhokomelo tse khethehileng

Ts'ebeliso e kopaneng ea Diabeteson MB le chlorpromazine ho litekanyetso tse phahameng (tse fetang 100 mg / ka letsatsi) e ka lebisa ho eketseha ha mahlaseli a glucose ea plasma ka lebaka la ho fokotseha ha secretion ea insulin. Ho khothalletsoa taolo ea glycemic ka hloko. Haeba ho hlokahala hore ho sebelisoe lithethefatsi hammoho, ho khothalletsoa hore tekanyetso ea moemeli oa hypoglycemic e khethoe ka bobeli nakong ea tsamaiso ea antipsychotic le ka mor'a ho tlohela.

Ka ts'ebeliso e ts'oanang ea GCS (bakeng sa ts'ebeliso ea kemiso le ea lehae / intraarticular, cutaneous, rectal management /) eketsa khatello ea tsoekere maling le nts'etsopele ea ketoacidosis (ho fokotseha ha mamello ho lik'habohaedreite). Ho laoloa ka hloko glycemic, haholo-holo qalong ea kalafo. Haeba o hloka ho sebelisa lithethefatsi mmoho, o ka hloka ho fetola tekanyetso ea moemeli oa hypoglycemic ka bobeli nakong ea tsamaiso ea GCS le kamora ho hlakoloa ha bona.

Ka ts'ebeliso e kopaneng ea li-agonists tsa beta2-adrenergic (ritodrin, salbutamol, terbutaline) eketsa bongata ba tsoekere maling. Ho lebisoa tlhokomelo e khethehileng ho bohlokoa ba taolo ea glycemic. Haeba ho hlokahala, ho khothalletsoa ho fetisetsa mokuli kalafo ea insulin.

Metsoako e lokelang ho ananeloa

Liphetho tsa sulfonylureas li ka ntlafatsa phello ea li-anticoagulants ha li kopane. Ho ka 'na ha hlokahala hore u ntlafatse tokiso ea litheko tsa anticoagulant.