Adebit: litaelo tsa tšebeliso, theko, litlhahlobo tsa lingaka le bakuli

Litlhokomelo li lokela ho fanoa hammoho le diuretics (haholo-holo tse tsoang ho thiazide). Ka lebaka la kotsi ea lactic acidosis, tlhahlobo ea mali e lokela ho etsoa likhoeli tse ling le tse ling tse tšeletseng, 'me ts'ebetso ea sebete le ea liphio e lokela ho hlahlojoa. Pele ho buuoa, phetoho ea kalafo ea insulin e ea hlokahala. Nakong ea kalafo, o ka se noe joala, hobane maemong a mang, ho se mamelle joala ho ka hlaha.

Polelo ea lihlopha tsa nosological

Tlohela maikutlo a hau

Lenaneo la Hona Joale la Litaba tsa Tlhokahalo, ‰

Setifikeiti tsa ho ingolisa tsa Adebit

• S-8-242 N2016

Webosaete ea semmuso ea k'hamphani RLS ®. Encyclopedia ea mantlha ea lithethefatsi le thepa ea bongaka ea semmuso ea Marang-rang ea Russia. Lenane la lithethefatsi Rlsnet.ru le fa basebelisi monyetla oa ho fumana litaelo, litheko le litlhaloso tsa lithethefatsi, tlatsetso ea lijo, lisebelisoa tsa bongaka, lisebelisoa tsa bongaka le lihlahisoa tse ling. Tataiso ea meriana e kenyelletsa tlhahisoleseling mabapi le sebopeho le mofuta oa tokollo, ts'ebetso ea pharmacological, matšoao a ts'ebeliso, contraindication, litla-morao, tšebelisano ea lithethefatsi, mokhoa oa ts'ebeliso ea lithethefatsi, lik'hamphani tsa meriana. Sesebelisoa sa lithethefatsi se na le litheko tsa meriana le lihlahisoa tsa meriana ho la Moscow le metseng e meng ea Russia.

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Lintho tse ling tse ngata tse khahlang

Litokelo tsohle li sirelelitsoe.

Ts'ebeliso ea thepa ea khoebo ha e lumelloe.

Tlhahisoleseling ena e etselitsoe litsebi tsa bongaka.

Adebit - litaelo, theko, litekolo le lipapatso tsa lithethefatsi

Adebit - moemeli oa antidiabetesic bakeng sa tsamaiso ea molomo bakeng sa bakuli ba sa itšetleheng ka insulin. Ha e bake hypoglycemia bathong ba phetseng hantle, e ka fanoa ka litlatsetso tsa sulfonylurea.

Phello ea kalafo

Setlhare sa antidiabetesic se tsoang molomong oa sehlopha sa Biguanide. E ka ntlafatsa ts'ebeliso ea tsoekere 'me ea ntlafatsa glycolysis ea anaerobic.

Adebit ha e bake hypoglycemia ho batho ba phetseng hantle. E kanna ea laeloa hammoho le li-antidiabetic tsa molomo tsa mofuta oa sulfonamide.

• Tlanya mofuta oa tsoekere ea lefu la tsoekere ho bakuli ba baholo, hammoho le kalafo e kopantsoeng le lintho tse tsoang ho sulfonylurea, ha u ntse u boloka tlhahiso ea insulin.
• Ho nona ka botebo holima lefu la tsoekere.
• Ho haelloa ke metabolism e tsoekere ea tsoekere (hammoho le insulin).

Contraindication

Acidosis kapa ho fumanoa hoa mabaka bakeng sa lactic acidosis: embolism ea matšoafo, ho se sebetse hantle ha pelo, ho senyeha ha methapo ea mokokotlo kapa hepatic, phokolo e matla ea mali, mafu a tšoaetsanoang, gangrene, pancreatitis e matla, feberu, hypovolemia, joala bo sa foleng, tšebeliso ea li-diuretics,Ho itukisetsa ho buoa le maemo ka mor'a ho buuoa, lilemo tsa senile, ho ima.

Mokhoa oa kopo

Tšebeliso le litekanyetso li beoa ke ngaka e eang. Tekanyetso ea pele e tsoa ho 100-150 mg letsatsi le letsatsi (ho fihla ho makhetlo a 3 a komporo e le 'ngoe), ka sekhahla se fokolang sa metsi a sa jeleng paate ka mor'a lijo.

Nakong e tlang, ho latela boemo ba mokuli, lethal dose le ka eketsoa ke letlapa le le leng ka matsatsi a mabeli kapa a mane. Tekanyo e phahameng ka ho fetisisa ka letsatsi ke matlapa a 300 mg kapa a 6, a arotsoeng ka litekanyetso tse 3 kapa tse 4.

Motsoako oa tlhokomelo hangata o na le 200 mg ka letsatsi (matlapa a 4).

Litla-morao

• Ho nyekeloa ke pelo, ho hlatsa, lets'ollo, ho felloa ke takatso ea lijo le tatso ea tšepe molomong. Litletlebo tsena lia khoneha ha ho nooa moriana ka mpeng e se nang letho, lia nyamela kamora ho fokotsoa ha tekanyetso ea nakoana.
• Malabsorption ea vithamine B12, lactic acidosis, idiosyncrasy. Nts'etsopele ea maemo a joalo e ka etsahala ka mokhoa o sa tsotelleng litlolo tsa litlhare.

Litaelo tse khethehileng

E hloka tšebeliso ea lithethefatsi ka hloko ka li-diuretics, li-thiazide derivatives (ka lebaka la kotsi ea lactic acidosis, hypovolemia), lithibela-pelehi tsa molomo (ka lebaka la ho fokotseha hoa ts'ebetso), corticosteroids (ba fokotsa phello ea Adebit), lithethefatsi tse eketsang nako ea ho fetoha ha mali (Adebit) e ntlafatsa phello ea tsona).

Molemong oa phekolo ea Adebite, ho lula ho hlokahala setšoantšo sa mali, hammoho le mesebetsi ea liphio le sebete, tse amanang le kotsi ea ho ba le lactic acidosis.

Haeba ho ba le mathata a ka mpeng ea mpa, ho otsela, ho hema ka potlako, etela ngaka hang-hang. Ho khomarela ka tieo lijong le ho khetholle joala ka ho felletseng, ka linako tse ling ho se mamellane ha tsona ho hlokometsoe.

Ho bakuli ba nang le ts'oenyeho ea lactose, mathata a ka mpeng a ka hlaha ka lebaka la litaba tsa eona matlapeng.

"Adebit" e bolokiloe ka mocheso oa kamore, e lahloa kamora hore nako e bontšitsoe ka har'a sephutheloana. Bophelo ba Shelf - lilemo tse 5.

TLHOKOMELISO MOTSAMAI

Ketso ea pharmacological

Phello e fokotsang tsoekere ea Adebit e kenyelletsa ho matlafatsoa ha tsoekere le ho kenella ka bongata linthong tse ngata (haholo-holo mesifa ea mesifa), ho theola ho ts'oaroa ha glucose ka mpeng e nyane le phetoho ea eona e kenang maling, le ho thibela gluconeogenesis ka har'a sebete. Sethethefatsi se kenya letsoho goncolysis ea anaerobic, e ntlafatsa tšohanyetso ea lisele ho insulin.

Adebit e baka tšenyo e fokolang, e fokotsa takatso ea lijo, e thusang ho ja le ho thusa ho fokotsa boima ba botenya. Ho kenyelletsa moo ho na le thepa ea "thrombolytic".

Tšusumetso ea kalafo e qala kamora lihora tse 2-4, e fihla hofihlella kamora lihora tse 5. Nako eohle ea ts'ebetso e fihlile ho lihora tse 8. Ntho ena e na le bioavailability e felletseng, e kenella ka potlako mokokotlong oa lijo. E epolloa ka liphio.

• mofuta oa 2 lefu la tsoekere ho batho ba baholo, hammoho le sulfonylureas le ho se sebetse hantle ha bona
• mofuta oa 1 lefu la tsoekere, hammoho le insulin, ha ho se na metabolism e tsoekere
• botenya.

Mokhoa oa ho nka ADEBIT

Re amohela lijo ka makhetlo a mabeli ka letsatsi: hoseng le mantsiboea. Motsoako oa pele ke 100-150 mg (1 letlapa makhetlo a 3 ka letsatsi). Tekanyetso ea letsatsi le letsatsi e lumellana le tsoekere ea mali, empa ha e fete 300 mg / letsatsi (matlapa a 6 ho litekanyetso tse tharo tse arohaneng). Litekanyetso li lokiselitsoe ke matlapa a 4 ka letsatsi.

Bakeng sa kalafo ea botenya, ho fanoa ka tekanyetso ea letsatsi le letsatsi ea 100 mg.

Ho sebelisana le lintho tse ling

Adebit e ka sebelisoa hammoho le insulin, moriana o matlafatsa le ho lelefatsa phello. Lintho tse kang chlorpromazine, lihormone tsa qoqotho, corticosteroids, le diuretics li fokolisa phello e fokotsang tsoekere ea Adebit.Salicylates, MAO inhibitors le litokisetso tsa sulfonylurea - ntlafatsa.

Tšebeliso e kopanetsoeng le lithibela-pelehi tsa li-hormone e fokolisa phello ea lithethefatsi tsena ka bobeli. Adebit e ntlafatsa ketso ea thrombolytics.

Ho ja Adebit ho lokela ho tsamaisana le ho lekola tsoekere ea mali kamehla le ho lekola ts'ebetso ea liphio.

Betaserc 24 mg - litaelo tsa tšebeliso, theko, litekolo, li-analogues

Kea le lumelisa bohle! Re ntse re tsoela pele ho lekola lithethefatsi, tse qalileng mona ka litšoantšo tsa Zovirax, tse ntseng li tsoela pele “mona” ka sengoloa sa enterofuril, ka nako eo ka li-analog tsa Sinupret, ebe karolong e reng “Selelekela ho Mekhoa e Phelang”. Kajeno sehlooho sa rona ke: "Betaserc 24 mg - litaelo tsa tšebeliso, theko, litekolo, li-analogues". Tabeng ena, ke se ke ngotse "mona" Ena ke tsoelo-pele.

Ho kula ha tsebe e ka hare, joalo ka methapo ea kutlo ea methapo kapa lefu la tsebe, le etsang hore motho a utloe a sa utloe. Li ka hlaha eseng botsofaling feela, empa le ho batho ba banyenyane ka mor'a ho ts'oasa tsebe e bohareng kapa ho sebelisa lithethefatsi tsa ototoxic.

Ha ho khonehe ho khutlisetsa ts'ebetso ea lisebelisoa tsa methapo ea kutlo haeba ho na le ts'enyehelo e mpe e sa foleng. Mathata a joalo a phekoloa feela nakong ea maloetse. Haeba lefu le qalile, joale ho thibela bonyatsi ho thibela ts'ebetso ea methapo, 'me ho sebelisoa litlhare tse eketsang trophism ea tsebe e kahare.

Mokhoa o mong oa phekolo ke betaserk 24 mg, litaelo tsa tšebeliso, theko, litekolo, li-analogues tse tla tšohloa sehloohong sena.

1.1 Lisosa le matšoao a mafu a tsebe e ka hare

Karolo e ka sehlohlolong ea tlhahlobo ea lihlahisoa le lipatlisiso tsa batho ba qalang e qala ka kotloloho le poloko. Ho na le lisele tsa kutlo tse utloang ho thothomela le melumo ea hlooho, ka hona li ikarabella bakeng sa ho utloa le ho leka-lekana. Mafu a tsebe e ka hare a ts'oaetso ebile aa fokola.

Ea pele e etsahala ka lebaka la ho kenella ha likokoana-hloko tse tsoang tsebeng e bohareng nakong ea tšoaetso ea vaerase kapa ea baktheria. Sesosa sa bobeli e kanna ea ba lefu la ho hloka pherekano kapa lefu la selefouno ka lebaka la mafu a methapo, khatello e mpe ea molumo kapa tšebeliso lithethefatsi tsa ototoxic.

Matšoao a senya tsebeng e ka hare ke ho lahleheloa ke kutlo, hammoho le lerata le ho lla litsebeng, ho tsekela, ho nyekeloa le pelo kapa ho lahleheloa ke botsitso. Empa ho bohlokoa ho nka hore haeba mokuli a le dizzis, 'me ho utloa ho tloaelehile, joale ho tsekela, joalo ka molao, ha ho amane le tsebe e ka hare.

1.2 Melao-motheo ea kalafo ea mafu a tsebe e ka hare

Ho bohlokoa hore bakuli ba utloisise hore haeba lisele tsa kutlo li shoele ka mokhoa o sa phekoleheng, kalafo e ke ke ea thusa ka ho khetheha. Ka hona, o hloka ho e qala kapele kamoo ho ka khonehang: ha matšoao a pele a ho senyeha ha kutlo le ho leka-lekana a etsahala.

Ts'ebetsong ea ho ruruha, lithibela-mafu li ngoletsoe kalafo, empa ha se li-ototoxic feela, hammoho le lithethefatsi tse khahlanong le ho ruruha tse imollang edema (diuretics, corticosteroids, tharollo ea hypertonic, antihistamines).

Ho ntlafatsa lisele tsa trophic, li-multivitamine, kalafo ea detoxification le lithethefatsi tse ntlafatsang lits'ebetso tsa metabolic bokong le phepelo ea mali a hae (nootropics) e khothalletsoa.

1.3 Betaserc 24 mg - litaelo

Ke ea sehlopha sa li-antihistamines, e leng analog ea maiketsetso ea mokena-lipakeng ea lokolloang nakong ea lintho tse kulang. E baka ho ruruha ha mesifa, vasodilation, ho fokotseha ha khatello ea mali, letlalo la ho hlohlona, ​​bronchospasm, ho thothomela le ho teneha ha membrane ea mucous.

Li-receptor tseo histamine e tlamang li kenang tsamaisong ea methapo ea kutlo le e bohareng, e bakang hlooho ea hlooho le migraines le ho tsekela.

Betaserk e tlama ho histamine receptors, ho kenyelletsa le tsebe e ka hare, ka hona e khona ho ntlafatsa boteng ba capillaries ea eona le lisele tsa trophic.

Ka lebaka la ho eketseha ha microcirculation ka beseng ea methapo e meholo ea methapo, khatello ea lisele e hlahang ka kotloloho ka molomong le hofihlelle. E boetse e khona ho ntlafatsa tšusumetso ea mokokotlo haufi le methapo ea kelello.

E thibela li-receptors ka har'a nuclei ea mohlahlobi oa vestibular.

Ka lebaka la ts'ebeliso ea betaserk, lerata le tinnitus li fokotsehile, litlhaselo tsa tsebiso ha li na seoelo, 'me ho utloa ho ntlafatsoa haholo, haholo matsatsing a pele a lefu lena. Betaserc e kenella ka potlako le ho tlosa 'mele ka botlalo ke liphio ka lihora tse 24, ntle le ho ipokellela eona, ka hona e loketse batho ba baholo.

1.4 Melao ea ts'ebeliso ea Betaserc 24 mg

Moriana ona o reretsoe bakuli ba nang le ts'ebetso e fokolang ea tlhahlobo ea li-curl le labyrinth; e thusa bakuli ba joalo ho sebetsana ka katleho le tlhaselo ea likhahla, e kopantsoeng le ho nyekeloa ke pelo, ho hlatsa, tinnitus le tahlehelo ea litsebe.

Ho bontšoa ka khatello ea tsebe e ka hare, lefu la Meniere kapa lefu, ho tsetselela le ho kobeha hoa boemo, le tsoelo-pele ea tahlehelo ea kutlo ea kutlo.

Betaserc 24 mg e laeloa kalafo e rarahaneng ea encephalopathy e ileng ea hlaha kamora ho lemala, hammoho le atherosclerosis ea likepe tsa mokelikeli le ho haella ha vertebrobasilar.

Contraindication mabapi le ts'ebeliso ea eona e tla ba asthma ea bronchial, hammoho le seso sa peptic sa mpa kapa duodenum e nang le ho fetelletsa. E ke ke ea sebelisoa bakeng sa allergies ho motsoako o ka sehloohong o sebetsang oa lithethefatsi kapa likarolo tsa lona tse ling.

E tšoaelitsoe basali ba baimana ho trimester ea pele, 'me ea bobeli le ea boraro ka linako tse ling e sebelisoa, empa ho latela matšoao le tlasa taolo ea ngaka. Moriana ona ha o khothalletsoe hape nakong ea ho beleha, hammoho le bana ba ka tlase ho lilemo tse leshome le metso e robeli, kaha ha ho na bopaki ba hore e sebetsa hantle ho fihlela lilemong tsena.

Ho bohlokoa ho nka hore betaserc e ke ke ea tahoa le li-antihistamine tse ling, hobane li fokotsa katleho ea pele.

1.5 Litla-morao

Bakuli ba hlokometse hore ts'ebeliso ea eona, boima bo ka mpeng, ho nyekeloa le pelo, ho hlatsa le lets'ollo li ka hlaha, ka lebaka leo ho tla hlokahala ho fokotsa tekanyetso, hape o tlameha ho sebelisa moriana feela ka mor'a ho ja. Litla-morao tsa mofuta oa makhopho a letlalo ha li sa tloaeleha.

Ka tšebeliso ea nako e telele, ho tsekela kamehla, ho hlakaha letlalo, bofubelu ba letlalo, bronchospasm le ho theoha ha khatello ea mali li ka hlaha. Matšoao ana a nyamela kamora ho khaotsa kalafo le matšoao a kalafo.

1.6 foromo ea ho lokolla, theko le tekanyetso

Likhamphani tsa meriana li fana ka lithethefatsi ka matlapa a 8,16 le 24 mg, ka har'a pakete ea tsona e ka ba likotoana tse 20, 30 kapa 60. Litsenyehelo tse tloaelehileng tsa blister ea matlapa a leshome betaserk 24mg - li-ruble tse ka bang 240, 16 mg - 220, le theko ea li-ruble tse 8 mg - 140.

Li nooa hang ka mor'a lijo ebe li hlatsuoa ka metsi a hloekileng. Ka tloaelo, mokuli o khothalletsoa matlapa a 1-2 ka letsatsi la 8 mg kapa tekanyo e le 'ngoe ka lethal la 16 mg makhetlo a mararo ka letsatsi,' me haeba e le 24 mg, joale e le 'ngoe habeli ka letsatsi.

1.8.1 Betahistine

Tsena li kenyelletsa meriana eohle e nang betahistine ho kenyeletsoa matlapa a nang le lebitso le tšoanang. Lisebelisoa tsena li na le se tšoanang bopaki le likhokahano. Litlamorao li tla tšoana.. Betahistine ha e kena-kenane le bokhoni ba ho khanna makoloi kapa ho etsa mosebetsi o amanang le khatello ea maikutlo.

O boetse o sebetsana hantle le hlooho le ho tsekela, tse hlahang ho basali qalong ea ho ilela khoeli.

Ke 'nete, bakuli ba hlokomela hore litholoana ts'ebeliso ea betagestin e tla ba feela kamora libeke tse peli tsa kalafo mme ha e lule e tsitsitse, leha e sebelisoa ka nako e telele ho tsekela ea fokotseha.

Empa ebe theko litokisetso li tlase haholo ho feta betaserc mme li loketse ho ja nako e telele le ho tloaela khafetsa.

1.8.2 Vestibo

Analog e 'ngoe ea betaserk ke kea leboha, ntho e sebetsang ea sesebelisoa sena le eona ke betahistine. Bakuli ba hlokomela phello e ntle ea kalafo ea moriana ona, leha ho le joalo, o nyamela ka potlako, o tlameha feela ho qeta tšebeliso ea eona. Analog ena ea beteserk le eona ha e theko e tlase - theko e tloaelehileng ha e joalo kea leboha li-ruble tse ka bang 140 bakeng sa matlapa a leshome.

Lihlopheng tse ling tsa lithethefatsi li sebelisetsoa ho phekola mafu a tsebe e ka hare, ho etsa mohlala, nakong ea methapo, bakuli ba fuoa meriana ea antibacterial le ea hormonal corticosteroid ho fokotsa matšoao a tšoaetso, hammoho le tharollo ea hypertonic ea glucose kapa magnesium sulfate ho fokotsa lenane la methapo ea kutlo le ho thibela khatello ea methapo ea kutlo e moqotetsane ea bony.

1.8.3 Cavinton le vinpocetine

Sehlopha se seng sa lithethefatsi tse fokotsang ho tsebiso ho bakuli, hape se ntlafatsang kutlo, ke lithethefatsi tse amang methapo e meholo ea methapo ea mali ea boko, e holisang li-capillaries. baemeli ba sehlopha sena, ba tummeng har'a lingaka, ke cavinton le vinpocetine.

Onykot e khatholla mesifa e boreleli ea lebota la methapo, e kenya letsoho kholisong ea eona, e fokotsa khatello ea mali, e eketsa phallo ea oksijene le glucose ho lisele tsa methapo.

1.8.4 Piracetam, Cinnarizine, Phezam, le Cerebrolysin

Nootropics e ka boela ea nkuoa e le li-analogues tsa betaserk - meriana e ntlafatsang metabolism liseleng tsa methapo le ho tsamaisa tšusumetso ho tsona, hammoho le ho matlafatsa lerako la methapo. Tsena li kenyeletsa piracetam, cinnarizine, fezam le cerebrolesin.

Ntlafatso ea ts'ebeliso ea bona ha e hlahe hanghang, empa e sebelisoa feela ka nako e telele le khafetsa hammoho le lithethefatsi tse ling, ho kenyelletsa li-anticoagulants (trental, pentoxifylline).

Mekhoa ena e thusa ho fokotseha ha mali le ho ntlafatsa phepelo ea mali bokong.

1.8.5 Vithamine ea sehlopha B

Sehlopha se seng sa lithethefatsi bakeng sa kalafo ea li-nerve neuritis ke Li-vithamine tsa Btseo, ka tšebeliso ea nako e telele, li ntlafatsa metabolism liseleng tsa methapo ebe li kenya letsoho ho fola, ka ho etsa joalo e fokotsa tinnitus le kizungu.

Ho latela moetlo, qetellong, video e buang ka sehlooho se fuoeng: "Betaserk"

Ho ile ha tsebisoa sengoloa: "Betaserk 24 mg - litaelo bakeng sa tšebeliso, theko, litekolo, li-analogues" Ke tšepa hore babali ba blog ena ba tla fumana ho le molemo ho itloaetsa lithethefatsi tse tummeng joalo ka betaserk, ho bala litaelo tsa eona bakeng sa tšebeliso, theko, litekolo, li-analogues.

Empa ke batla ho u hopotsa hore moriana ona o na le matšoao a oona, mme haholo li-contraindication, ka hona ho ka se khonehe ho o sebelisa ntle le ho buisana le ngaka ea hau.

Buformin * (Buformin *) A10BA03 Buformin

• Hypoglycemic synthetic le li-agents tse ling

• E mellitus ea tsoekere e sa itšetleheng ka insulin
• Botenya ba E65-E68 le mefuta e meng ea phepo e nepahetseng

Letlapa le le leng le na le buformin hydrochloride 50 mg, ka paketeng e nang le lithupa tse 20 tsa likhomphutha, ka lebokoseng la 2 la mabokose.

Matšoao a ho sebelisoa

Adebit e sebelisoa bakeng sa bakuli ba sa ts'epeng insulin. Ho amoheloa ha chelete ke batho ba phetseng hantle ha ho bake hypoglycemia.

Adebit ea lithethefatsi e etselitsoe:

• mofuta oa lefu la tsoekere
• botenya
• litlamorao tsa phepo e nepahetseng.

Moriana o bontšoa bakeng sa metabolism e sa tsitsang ea tsoekere hammoho le kalafo ea lihomone.

Buka ea litaelo

Ketso ea mantlha ea lithethefatsi tsa Adebit ke hypoglycemic.

E fokotsa boemo ba tsoekere ho plasma, e laola ho fokotseha ha eona mots'eare, hape e fokotsa tlhoko ea mokuli ea insulin. Sesebelisoa ke sa sehlopha sa Biguanides.

E nkoa ka molomo. E susumetsa glycolysis ea anaerobic liseleng tse ka thoko. Buformin e le karolo ea Adebit e thusa ho hatella tsoekere maling. Maemong ana, ho na le phokotseho ea ho monya ha tsoekere e tsoang methapong ea lijo.

Setlhare se thusa ho fokotsa takatso ea lijo. Buformin e qala ho nka lihora tse 'maloa ka mor'a ho nka moriana ebe e boloka thepa ea eona ka lihora tse robeli.

Ha o sebelisa Adebit, tšebelisano ea eona le lithethefatsi tse ling e lokela ho tsotelloa:

1. thepa e theolelang tsoekere ea lithethefatsi ea fokola ha e nkuoa ka melemo ea phenothiazine, lihormone tse susumetsang tsa qoqotho, MAO inhibitors, salicylates,
2. sebelisa moriana ka hloko ka diuretics. Lactic acidosis le hypovolemia li ka hlaha,
3. lithethefatsi li hatella ketso ea urokinase,
4. ka ts'ebeliso e ts'oanang ka lithibela-pelehi le li-corticosteroids, ho fokotseha ho kopaneng hoa litlamorao tsa lithethefatsi ka bobeli ho etsahala.

Ha u nka Adebit, phello ea thrombolytics ea matlafatsoa.

Tšebeliso ea lithethefatsi e bolela ho bolokoa ha litaelo tse khethehileng:

• ho hlokahala hore ho hlahlojoe glycemia khafetsa le chaba ea tsoekere ea moriti oa letsatsi le letsatsi,
• tekanyetso ea insulin e lokela ho fokotsoa butle butle,
• nakong ea phekolo ea lithethefatsi, o tlameha ho latela lijo tse thata, o khetha lijo tse nang le index e tlase ea glycemic.

Ho noa joala ha u ntse u sebelisa Adebit ho thibetsoe ka thata. Ka hloko, ho fuoa phekolo bakeng sa ho se mamelle lactose.

Foromo ea tokollo ea Adebite - matlapa, a kentsoeng ka har'a siling ea blister ea likotoana tse 20. Ho paka - lebokose la karete. Ho boloka moriana ho tlameha ho fihlela litlhokahalo tse itseng: ka mocheso oa kamoreng mme o sa feteng lilemo tse hlano.

Litaelo tsa ho nka moriana li na le litlhaloso tsa mokhoa oa tšebeliso le oa litekanyetso.

Tekanyetso ea pele e tsoa ho 100 ho isa ho 150 mg ka letsatsi, e arotsoeng makhetlo a mabeli kapa a mararo, nka pilisi e le 'ngoe ka mor'a lijo, e hlatsoitsoe ka metsi.

Palo ea matlapa e eketsoa ke e le 'ngoe ka mor'a matsatsi a 2-4. Tekanyo e phahameng ea letsatsi le letsatsi ke 300 mg ea moriana, o arotsoe ka tekanyetso ea 3-4. Ho boloka phello, ba noa 200 mg ea moriana ka letsatsi, ba o hatella ka makhetlo a mane.

Livideo tse amanang

Kakaretso ea lithethefatsi tsa lefu la tsoekere la mofuta oa 2:

Melemo ea pholiso ea Adebit e ipapisitse le phello ea eona ea hypoglycemic. Ke moemeli oa antidiabetes. Ho bakuli ba nang le boima ba 'mele bo feteletseng, ha ho nkoa, boima ba' mele bo fokotseha ka lebaka la bokhoni ba Adebit ba ho fokotsa takatso ea lijo.

Har'a tse ling tsa litlamorao ke lets'ollo, bohloko ba epigastric, ka hona ha ua lokela ho bo sebelisa ho ba nang le mafu a gastrointestinal. Setlhare sena se bontšoa bakeng sa lefu la tsoekere le sa itšetleheng ka insulin, hammoho le bokuli bo tsamaeang le botenya. Khahlano le semelo sa ho nka moriana, o lokela ho latela lijo, ho itlopa joala le ho phela bophelo bo phetseng hantle.

• E tsitsisa maemo a tsoekere nako e telele
• E khutlisa tlhahiso ea insulin ea "pancreatic"

Ithute haholoanyane. Eseng lithethefatsi. ->

Mokhoa oa Tiriso:

Abela ka hare ka lijo.

Joaloka moemeli oa lefu la lefu la tsoekere, nka, ho qala ka 0,1 g ka letsatsi (50 mg hoseng le mantsiboea), ho latela phetoho ea tsoekere maling le moroto, lethalinyana le ka eketseha butle-butle ka 50 mg ka letsatsi, empa tekanyetso ea letsatsi le letsatsi ha ea lokela ho feta 300 mg

Litlhoko tsa tlhokomelo hangata hangata li 50-100 mg hoseng le 50 mg ka mantsiboea. Ha e kopantsoe le insulin, tekanyetso ea morao-butle e ea fokotsoa tlasa taolo ea glucose maling le moroto.

Hammoho le litokisetso tsa sulfonylurea, glibutide e beoa maemong a ha ba pele ba sa khone ho fokotsa hyperglycemia (tsoekere e phahameng ea mali) le glucosuria (ho ba teng ha tsoekere ka har'a moroto) ho ea boemong bo hlokahalang. hammoho le anorexigenic / takatso ea lijo / lithethefatsi / lithethefatsi).

Matlapa a nkileng nako e telele a beoa moqolo o le mong oa hoseng (hoseng), butle-butle o eketsa tekanyetso ho matlapa a 4 (hoseng le mantsiboea ka mor'a ho ja).

Liketsahalo tse sa thabiseng:

Glibutide e mamelleha hantle, empa ho lahleheloa ke takatso ea lijo, ho nyekeloa, ho hlatsa, lets'ollo (lets'ollo), le tatso ea tšepe e molomong li ka bonoa. Hamorao ka mor'a ho qala kalafo (kamora khoeli kapa ho feta), bofokoli, ho fokotsa boima ba 'mele hoa khoneha.

Litla-morao hangata li tloha kapele ka phokotso ea litekanyetso kapa ho tlohela lithethefatsi.

Maemo a polokelo:

Setlhare se tsoa lenaneng B. Sebakeng se omileng.

Buformin hydrochloride, Adebit, Butyl biguanide, Gliporal, Glibigid hydrochloride, Krebon, Silubin.

Butylbiguanide hydrochloride. White phofo ea kristale e tsoekere. Ho qhibilihisoa habonolo ka metsing le joala. Letlapa le le leng la ketso ea mofuta oa nako e telele (ea nako e telele) le na le: 0.17 g ea buformin tosylate, e tsamaellanang le 0,1 g ea ntho e sebetsang (glibutide).

Litokisetso tsa ketso e ts'oanang:

Diaformin (Diaformin) Glucovans (Glucovance) Oltar (Oltar) Glyukofazh (Glucophage) Maninil (Maninil)

Ha ua fumana tlhaiso-leseling eo u e hlokang?
Litaelo tse felletseng tsa lithethefatsi "glibutide" li ka fumanoa mona:

Lingaka tse ratehang!

Haeba u na le boiphihlelo ba ho fana ka moriana ona ho bakuli ba hau - arolelana sephetho (tlohela maikutlo)! Na moriana ona o thusitse mokuli, na ho bile le litla-morao life nakong ea kalafo? Phihlelo ea hau e tla khahla basebetsi-'moho le uena hammoho le bakuli.

Bakuli ba ratehang!

Haeba moriana ona o ne o reretsoe meriana ena 'me u bile le tlhahlobo ea kalafo, mpolelle hore na e ea sebetsa (hore na ea thusa), ho na le litla-morao, tseo u li ratang / tseo u sa li rateng. Batho ba likete ba batla tlhahlobo ea marang-rang ea meriana e fapa-fapaneng. Empa ke ba fokolang feela ba ba siileng. Haeba uena ka bouena u sa tlohele maikutlo ka taba ena - ba bang kaofela ha ba na seo ba ka se balang.

Ke leboha haholo!/ sitemap-index.xml

Tlhaloso ea meriana "Adebit"

Ketso ea pharmacological e fokotsa tsoekere ea mali le ho feto-fetoha ha eona ha letsatsi le letsatsi, tlhoko ea insulin.

Matšoao a ho sebelisoa

• Type II lefu la tsoekere mellitus (hammoho le lintho tse tsoang ho sulfonylurea), botenya bo bongata ba tsoekere, metabolism e sa tsitsang ea tsoekere (hammoho le insulin).

• Matlapa a 50 mg
• blister 20, lebokose (lebokose) 2.

Pharmacodynamics ea moetsi oa lithethefatsi Hypoglycemic bakeng sa tsamaiso ea molomo ho tsoa sehlopheng sa li-biguanides. E na le tšusumetso e tobileng ea glycolysis ea anaerobic ho lithane tsa pherekano.

E hatella gluconeogeneis ka har'a sebete, e fokotsa ho monya ha tsoekere maling ka mpeng (e thibella alpha-glycosidases ea mala, e fokotsa ho phatloha ha enzymatic ea di-, oligo- le polysaccharides ho monosaccharides), e fokotsa takatso ea lijo.

E fokotsa dikahare tsa lero la plasma glucagon, e phahamisa maikutlo a lisele tsa ho kenella ka har'a insulin ho li-insulin receptors. Ho qala ha ts'ebetso ke kamora lihora tse 2-4, nako ea ts'ebetso e ka ba lihora tse 8.

Contraindication

• Hypersensitivity, ketonuria, hyperglycemic coma, hypoglycemia, ho ima, ho nyeka. Lactic acidosis (ho kenyelletsa le nalane)
• hepatic le / kapa ho hloleha ha renal, CHF, ho hloleha ho phefumoloha, ho ruruha ho matla ha myocardial, ho lemalla joala bo sa foleng, feberu, mafu a tšoaetsanoang, albinuria khahlano le semelo sa lefu la tsoekere, lefu la tsoekere.

Litla-morao: Ho fokotseha takatso ea lijo, ho nyekeloa ke pelo, ho hlatsa, ho fokola, ho theola boima ba 'mele, gastralgia, lactic acidosis, lets'ollo, tatso ea "tšepe" molomong, le lintho tse ling tse sa sebetseng hantle.

Tekanyetso ka hare, Letlapa le le leng. Makhetlo a 2-3 ka letsatsi ka mor'a lijo. Tekanyetso e kholo ea letsatsi le letsatsi ke 300 mg ho tekanyetso ea 3-4.

Matšoao a Kakaretso ea Litaba tsa ho fetela ka bongata: hypoglycemia, hypoglycemic coma.

Ho sebelisana le lithethefatsi tse ling Phello ea hypoglycemic e fokotsoa ke melemo ea phenothiazine, corticosteroids, lihormone tse susumetsang tsa qoqotho, li-estrogens, diuretics, li-inhibitors tsa MAO, salicylates.

Litaelo tse ikhethileng tsa ho amoheloa hoa hlokahala ho hlokomela khafetsa tlhahiso ea tsoekere ea ka mehla moriring, boemo ba glycemia. Ha o kenella kalafo le buformin, tekanyetso ea insulin e fokotseha butle butle.

Maemo a polokelo B: Ka mocheso oa kamore.

Bophelo ba Shelf likhoeli tse 60.

Ho thusang Bilobil: litaelo le litlhahlobo

Pheko ea tlhaho ea Bilobil ke sebopeho sa kelello.

E ikemiselitse ho ntlafatsa ts'ebetso ea boko le tsamaiso ea methapo. E entsoe motheong oa limela tsa boikoetliso ba boikoetliso bo tsoang sehlopheng sa li-ginkgo tse mebala e 'meli. Mofuta ona oa li-conifers o tsoa bochabela ho Chaena, empa o lengoa lirapeng tse ngata tsa lefats'e tsa limela.

Leqepheng lena o tla fumana leseli lohle mabapi le Bilobil: litaelo tse felletseng tsa ts'ebeliso ea lithethefatsi ena, litheko tse tloaelehileng mefuteng ea meriana, hammoho le litlhahlobo tsa batho ba seng ba sebelisitse Bilobil. U batla ho tlohela maikutlo a hau? Ka kopo ngola maikutlo.

Sokolla foromo le sebopeho

Li-capsules tse sootho tsa 'mala o sootho. Li-capsules li na le phofo ea tan e nang le likaroloana tse hlakileng tse lefifi.

• K'hasete e le 'ngoe e na le ntho e sebetsang: Ho omisoa hoa makhasi a ginkgo biloba - 40 mg, e lekantsoeng hore e be le 9.6 mg ea flavono glycosides ea ginkgo le 2.4 mg ea terpene lactones (ginkgolides le bilobalides) ho 40 mg.
• Lihlahisoa, lactose monohydrate, starch ea poone, talc, anhydrous colloidal silicon dioxide, magnesium stearate.
• Khetla ea Capsule: gelatin, indigotine (E132), azorubine (E122), oxide e khubelu ea tšepe * (E172), oxide oxide e ngata (E 172), titanium dioxide (E 171).

Phello ea pharmacological

Bilobil ke angioprotector ea semela. Ka lebaka la taba ea hore motsoako oa moriana o kenyelletsa ginkgo biloba extract, e leng terpene lactones le flavone glycosides, likarolo tsa eona tse sebetsang li matlafatsa haholo le ho phahamisa bokhoni ba marako a methapo ea mali, hammoho le ho ntlafatsa bokhoni ba rheological ba mali.

Litaelo tsa Bilobil li boetse li bonts'a hore lithethefatsi li laola ka nepo phello e itšetlehileng ka lethathamo tsamaisong ea pelo le methapo, li eketsa molumo oa methapo, li laola ts'ebetso ea ho tlatsa methapo ea mali ka mali, mme e hlapolla methapo e meholo ea methapo.

Ho sebelisana le lithethefatsi

Bilobil ha ea lokela ho laeloa bakuli ba tloaetseng ho sebelisa lithethefatsi tse theolelang ho fokotseha ha mali (mohlala, acetylsalicylic acid le litlhare tse ling tse seng khahlanong le ts'oaetso tsa antiidal, anticoagulants e tobileng le e sa tobang. Motsoako ona o ka eketsa menyetla ea ho tsoa mali ka lebaka la ho lelefala ha nako ea ho soetseha.

Re nkile maikutlo a batho mabapi le lithethefatsi Bilobil:

1. Tshepo Kamora hore ho nkuoe methapo ea methapo ea kutlo ea mali le methapo ea mali bokong, Bilobil Forte o laetse ngaka, e noele hoo e ka bang selemo mme e sa utloisise hore na hobaneng khatello e ba tlase le 10070, mme e etsahetse le tlase, mme pulse ea tlolela ho 120, a ikutloa a le mobe haholo, a tlohela ho nwa mme hanyane ka hanyane tsohle tsa eba ho fola, e le hore e mong a fole mme e mong a holofetse, o hloka ho ba hlokolosi haholo ka moriana ona. Bophelo bo botle ho bohle.
2. Galina. O ile a noa khoeli ka mafolofolo, a lokolloa ho cervical osteochondrosis. Hlooho ke pono e koahetsoeng ke maru. Ha ho a thusa letho.
3. Olga Ke ile ka nka li-capsules kamora ho hlaseloa ke stroke ho khothaletso ea ngaka ho tlosa litlamorao tse mpe. "Bilobil" e thusitse ho tlosa tinnitus le memori e ntlafalitsoeng.
4. Zina. Ho theko e boima haholo ha ho bolele ho betere! Bilobil Intens 120mg: pakete ea li-capsules tse 60 e bitsa li-ruble tse 970, theko ea tanakan 40mg bakeng sa matlapa a 90 a 1580, ha tanakan e sa nthuse, mme likhahla tsa Bilobil li ile tsa nyoloha. Mathata a ho hopola a hloka tharollo ka mokhoa oa sethethefatsi sa boleng bo holimo, se tšepahalang. Bilobil Intensity e ile ea phekoloa mme ha ke sa na bothata ba ho hopola. Mme hlooho ha e peteke, ha e utloe bohloko. Empa ntho ea bohlokoa ke hore ka hlooho e hlakileng ho bonolo haholoanyane ho sebetsa le ho etsa lintho tsa letsatsi le letsatsi.
5. Olya. Ke ile ka noa thupelo ea likhoeli tse tharo ea bilobil intens. Ho ikutloa o le motle. Hlooho ea ka e ile ea khanya, ho bonolo ho nahana, ke hopola ntho e ngoe le e ngoe 'me ha ke ferekanye letho. Maikutlo a sa thabiseng a kang ho tsekela a felile, 'me bokhoni ba ho lemoha bo eketsehile joaloka bongoaneng. Bilobil o molemo ho feta lithethefatsi tse ngata tse nang le ginkgo, sena ke setlhare, eseng se sebe, sa tlhaho ebile se matla, ka hona ke ikutloa ke le moholo. Pele o ne a noa ginkoom, empa ha ho na litholoana. Kamora ho koenya, ke fetela bobe bohle. Mme Bilobil ke sethethefatsi. E lokela chelete ka kotloloho.

Lingaka tse ngata li fana ka bopaki ba hore ho rengoa ha sefate sa ginkgo ke sona feela setlhare se ntlafatsang ts'ebeliso ea kelello ho bakuli ba tsofetseng. Leha ho le joalo, liphuputso li boetse li bontšitse hore kamora ho khaoloa ha Bilobil ho bakuli ba sehlopha sena, ho khutla hoa matšoao a amanang le lilemo ho a bonoa.

Manonyeletso a meriana ke meriana Bilobil, Vitrum Memori, Gingium, Ginos, Memoplant le Tanakan.

Li-analogues tsa Bilobil ke lithethefatsi tse kang:

• Memantine
• Memorel,
• Noojeron
• Akatinol Memantine,
• Alzeym
• Intellan
• Memaneirin
• Memorant
• Maruks
• Memantinol
• Memikar.

Pele u sebelisa li-analogues, etela ngaka ea hau.

Sehlopha sa tliliniki le meriana

Sethethefatsi se ntlafatsang ho potoloha ha 'mele le ho potoloha.

Lipehelo tsa Khefu ea Litlama

E lokolloa ntle le lengolo la ngaka.

Bilobil e bokae? Theko e tloaelehileng literekeng tsa litlama e boemong ba li-ruble tse 550.

Sokolla foromo le sebopeho

Li-capsules tse sootho tsa 'mala o sootho. Li-capsules li na le phofo ea tan e nang le likaroloana tse hlakileng tse lefifi.

• K'hasete e le 'ngoe e na le ntho e sebetsang: Ho omisoa hoa makhasi a ginkgo biloba - 40 mg, e lekantsoeng hore e be le 9.6 mg ea flavono glycosides ea ginkgo le 2.4 mg ea terpene lactones (ginkgolides le bilobalides) ho 40 mg.
• Lihlahisoa, lactose monohydrate, starch ea poone, talc, anhydrous colloidal silicon dioxide, magnesium stearate.
• Khetla ea Capsule: gelatin, indigotine (E132), azorubine (E122), oxide e khubelu ea tšepe * (E172), oxide oxide e ngata (E 172), titanium dioxide (E 171).

Phello ea pharmacological

Bilobil ke angioprotector ea semela. Ka lebaka la taba ea hore motsoako oa moriana o kenyelletsa ginkgo biloba extract, e leng terpene lactones le flavone glycosides, likarolo tsa eona tse sebetsang li matlafatsa haholo le ho phahamisa bokhoni ba marako a methapo ea mali, hammoho le ho ntlafatsa bokhoni ba rheological ba mali.

Litaelo tsa Bilobil li boetse li bonts'a hore lithethefatsi li laola ka nepo phello e itšetlehileng ka lethathamo tsamaisong ea pelo le methapo, li eketsa molumo oa methapo, li laola ts'ebetso ea ho tlatsa methapo ea mali ka mali, mme e hlapolla methapo e meholo ea methapo.

Matšoao a ho sebelisoa

Bilobil e fuoe li-pathologies tse ngata tsa tsamaiso ea methapo, hammoho le matšoao a fapaneng le syndromes, har'a tsona:

• Matšoenyeho
• Tinnitus.
• Ho hloka boroko
• Dyscirculatory encephalopathy, haholo-holo ka ho se sebetse hantle.
• Dizziness, haholo-holo e bakoang ke lisosa tsa vascular.
• Fokotsa nako ea tlhokomelo.

Bilobil e ka sebelisoa hape kalafong e rarahaneng ha ho e-na le mathata a potoloha ka har'a likepe tsa libaka tse tlase (tloaelo ea angiosurgery).

Contraindication

Hangata lithethefatsi li mamelloa hantle ke bakuli, leha ho le joalo, maemong a ikhethileng, nts'etsopele ea litla-morao tse joalo e ile ea hlokomeloa:

• Ho tloha tsamaisong ea methapo e bohareng: ho opeloa ke hlooho, ho teneha ho eketsehileng.
• Litla-morao:
• Ho tsoa ho ts'ilo ea lijo: ho nyekeloa pelo, ho hlatsa, setofo se holofetseng.

Ka nts'etsopele ea maikutlo a tebileng a ho kula, ho tlosoa hoa lithethefatsi hoa hlokahala.

Nts'etsopele ea litla-morao e ne e bonoa hangata ha ho nooa moriana Bilobil Intens, hammoho le ho bakuli ba tsofetseng ba nang le tekanyetso e phahameng ea lithethefatsi.

Bokhachane le pelehi

Ka lebaka la khaello ea tlhaiso-leseling e lekaneng ea bongaka, Bilobil ha e khothalletsoe ho sebelisoa nakong ea kemaro le nakong ea ho anyesa.

Litaelo tsa ho sebelisoa

Litaelo tsa tšebeliso li bontša hore Bilobil o nkuoa ka molomo. K'habeche e lokela ho metsoa ka metsi a mangata, ho sa tsotelehe lijo.

1. Dyscirculatory encephalopathy ea li-etiologies tse fapaneng: likhahla tse 1-2. Makhetlo a 3 / ka letsatsi
2. Mathata a amanang le ho hlaseloa ke letsoele (chizeloselese, tinnitus, hypoacusia), senile macular degeneration, retinopathy ea lefu la tsoekere: li-1. Makhetlo a 3 / ka letsatsi
3. Tšitiso ea ho potoloha ha mali le phallo ea mali ka bongata (ho kenyelletsa le arteryopathy ea maoto le matsoho), lefu la Raynaud: 1 li-cap. Makhetlo a 3 / ka letsatsi

Matšoao a pele a ntlafatso a hlaha hangata kamora khoeli e le 'ngoe. Nako ea phekolo ke bonyane likhoeli tse 3 (haholo-holo ho bakuli ba tsofetseng). Thupelo ea bobeli e ka etsahala kamora ho buisana le ngaka.

Litlamorao

Ho nwa moriana ho ka baka litlamorao tse latelang: ho tsekela, ho nyekeloa, ho hlatsa, ho opeloa ke hlooho, ho ruruha, lekhopho la letlalo, ho hlohlona, ​​kutlo le ho se bone hantle, tšupa ea mali ea ka mpeng, khaello ea mali le ho hloka boroko.

Maemong a mang, bilobil e ka baka ho tsoa madi le hemorrhege bokong.Sena se sebetsa haholo maemong ha moriana o nooa hammoho le lihokelo tsa mali. Ka kakaretso, litla-morao tsa moriana li bonoa hangata ebile ke tsa nakoana. Leha ho le joalo, haeba li etsahala, o lokela ho etela ngaka hang-hang.

Bongata

Haeba palo e fetisitsoe, litlamorao tsa karabelo e mpe li ka ntlafatsoa. Phekolo ke ea setso, ho latela matšoao.

Litaelo tse khethehileng

Phello ea kalafo ea lithethefatsi e hlaha kamora nako e ka bang khoeli e le ngoe ea ho sebelisa moriana. Haeba nakong ea phekolo ea lithethefatsi ho na le ho senyeha ka tšohanyetso, tahlehelo ea kutlo, tinnitus kapa ho tsekela ho hlaha, o tlameha ho khaotsa ho sebelisa lithethefatsi mme o batle keletso ea bongaka ka potlako.

Ha ho kgothaletswe ho khetha Bilobil ho bakuli ba nang le galactose kapa glucose malabsorption syndrome, congenital galactosemia kapa bofokoli ba congenital lactase, hobane lactose ke karolo ea eona.

Ho sebelisana le lithethefatsi

Bilobil ha ea lokela ho laeloa bakuli ba tloaetseng ho sebelisa lithethefatsi tse theolelang ho fokotseha ha mali (mohlala, acetylsalicylic acid le litlhare tse ling tse seng khahlanong le ts'oaetso tsa antiidal, anticoagulants e tobileng le e sa tobang. Motsoako ona o ka eketsa menyetla ea ho tsoa mali ka lebaka la ho lelefala ha nako ea ho soetseha.

Re nkile maikutlo a batho mabapi le lithethefatsi Bilobil:

1. Tshepo Kamora hore ho nkuoe methapo ea methapo ea kutlo ea mali le methapo ea mali bokong, Bilobil Forte o laetse ngaka, e noele hoo e ka bang selemo mme e sa utloisise hore na hobaneng khatello e ba tlase le 10070, mme e etsahetse le tlase, mme pulse ea tlolela ho 120, a ikutloa a le mobe haholo, a tlohela ho nwa mme hanyane ka hanyane tsohle tsa eba ho fola, e le hore e mong a fole mme e mong a holofetse, o hloka ho ba hlokolosi haholo ka moriana ona. Bophelo bo botle ho bohle.
2. Galina. O ile a noa khoeli ka mafolofolo, a lokolloa ho cervical osteochondrosis. Hlooho ke pono e koahetsoeng ke maru. Ha ho a thusa letho.
3. Olga Ke ile ka nka li-capsules kamora ho hlaseloa ke stroke ho khothaletso ea ngaka ho tlosa litlamorao tse mpe. "Bilobil" e thusitse ho tlosa tinnitus le memori e ntlafalitsoeng.
4. Zina. Ho theko e boima haholo ha ho bolele ho betere! Bilobil Intens 120mg: pakete ea li-capsules tse 60 e bitsa li-ruble tse 970, theko ea tanakan 40mg bakeng sa matlapa a 90 a 1580, ha tanakan e sa nthuse, mme likhahla tsa Bilobil li ile tsa nyoloha. Mathata a ho hopola a hloka tharollo ka mokhoa oa sethethefatsi sa boleng bo holimo, se tšepahalang. Bilobil Intensity e ile ea phekoloa mme ha ke sa na bothata ba ho hopola. Mme hlooho ha e peteke, ha e utloe bohloko. Empa ntho ea bohlokoa ke hore ka hlooho e hlakileng ho bonolo haholoanyane ho sebetsa le ho etsa lintho tsa letsatsi le letsatsi.
5. Olya. Ke ile ka noa thupelo ea likhoeli tse tharo ea bilobil intens. Ho ikutloa o le motle. Hlooho ea ka e ile ea khanya, ho bonolo ho nahana, ke hopola ntho e ngoe le e ngoe 'me ha ke ferekanye letho. Maikutlo a sa thabiseng a kang ho tsekela a felile, 'me bokhoni ba ho lemoha bo eketsehile joaloka bongoaneng. Bilobil o molemo ho feta lithethefatsi tse ngata tse nang le ginkgo, sena ke setlhare, eseng se sebe, sa tlhaho ebile se matla, ka hona ke ikutloa ke le moholo. Pele o ne a noa ginkoom, empa ha ho na litholoana. Kamora ho koenya, ke fetela bobe bohle. Mme Bilobil ke sethethefatsi. E lokela chelete ka kotloloho.

Lingaka tse ngata li fana ka bopaki ba hore ho rengoa ha sefate sa ginkgo ke sona feela setlhare se ntlafatsang ts'ebeliso ea kelello ho bakuli ba tsofetseng. Leha ho le joalo, liphuputso li boetse li bontšitse hore kamora ho khaoloa ha Bilobil ho bakuli ba sehlopha sena, ho khutla hoa matšoao a amanang le lilemo ho a bonoa.

Manonyeletso a meriana ke meriana Bilobil, Vitrum Memori, Gingium, Ginos, Memoplant le Tanakan.

Li-analogues tsa Bilobil ke lithethefatsi tse kang:

• Memantine
• Memorel,
• Noojeron
• Akatinol Memantine,
• Alzeym
• Intellan
• Memaneirin
• Memorant
• Maruks
• Memantinol
• Memikar.

Pele u sebelisa li-analogues, etela ngaka ea hau.

Maemo a polokelo le bophelo ba sehatsetsing

Setlhare sena se loketse ho sebelisoa lilemo tse tharo. Se ke oa fana ka monyetla oa ho bana, sireletsa ho tloha leseli. Mocheso oa polokelo 200C.

Sehlopha sa tliliniki le meriana

Inhibitor ea H + -K + -ATPase. Lithethefatsi tsa antiulcer

Fomu ea tokollo, sebopeho le sephutheloana

◊ Li-capsules tsa Enteric gelatin e thata, saese ea 3, e nang le 'mele o mosoeu le' mala o moputsoa, ​​litaba tse ka har'a likhapetla tsena li ngotsoe ka bophara ho tloha ho bosoeu ho isa ho bosoeu ka tisi e bolila kapa e putsoa.

* rabeprazole, pellet ntho 8,5% - 118 mg.

Baeti: libaka tsa tsoekere (sucrose - 99.83%, povidone - 0,17%) - 71.46 mg, sodium carbonate - 1,66 mg, talc - 1.77 mg, titanium diode - 0,83 mg, hypromellose - 14,75 mg.

Ba hlahisang likhetla tsa pellet: hypromellose phthalate - 15.94 mg, joala ba cetyl - 1.59 mg.
Karolo ea khalase ea lebili le thata ea gelatin 3: setopo sa capsule - titanium dioxide - 2%, gelatin - ho fihla ho 100%, capule cap - titanium dioxide - 2%, dae e putsoa e nang le patsi - 0,0176%, dae e ntšo ea daemane - 0,0051%, gelatin - ho fihla 100%.

Li-pcs tse 5. - Liphutheloana tsa blister (1, 2, 3) - lipakete tsa karete. - Liphutheloana tsa blister (1, 2, 3) - lipakete tsa karete ea likarete. 10 likhomphutha. - Liphutheloana tsa blister (1, 2, 3) - lipakete tsa karete.

14 li-PC. - Liphutheloana tsa blister (1, 2, 3) - mekotla ea likarete tse 15 likhomphutha. - Liphutheloana tsa blister (1, 2, 3) - mekotla ea likarete tse 20 likhomphutha tse 20. - Liphutheloana tsa blister (1, 2, 3) - lipakete tsa karete.

Li-pcs tse 30 - Liphutheloana tsa blister (1, 2, 3) - lipakete tsa karete.

Mofumahali

Tlhahiso le kabo

Rabeprazole e kenella ka potlako ka popelong, Cmax e plasma ea mali e fihlella lihora tse ka bang 3.5 ka mor'a tsamaiso ka tekanyo ea 20 mg. Liphetoho ho Cmax ho plasma ea mali, litekanyetso tsa AUC tsa rabeprazole li kahare ho litekanyetso ho tloha ho 10 ho isa ho 40 mg.

Boaoavailability e felletseng ka mor'a taolo ea molomo ka tekanyo ea 20 mg (bapisoa le iv) e ka ba 52%. Ntle le moo, bioavailability ha e fetohe ka litekanyetso tse ngata tsa rabeprazole. Leha e le nako ea ho sebelisa lithethefatsi motšehare, kapa tsamaiso e tšoanang ea li-antacid ha e ame ho amoheloa ha rabeprazole.

Ho nka lithethefatsi ka lijo tse nang le mafura ho fokotsa ho kenngoa ha rabeprazole lihora tse 4 kapa ho feta, leha ho le joalo, Cmax kapa boemo ba ho fetoloa ha bo fetole.

Ho tlangoa ha rabeprazole ho liprotheine tsa plasma hoo e ka bang 97%.

Metabolism le excretion

Metabolite e ka sehloohong ke thioether (M1). Metabolite e le 'ngoe feela e sebetsang ke desmethyl (M3), leha ho le joalo, e ne e ikemiselitsoe ka khatello e tlase ho karolo ea morupeluoa a le mong feela ea thuto ka mor'a ho nka rabeprazole ka tekanyo ea 80 mg.

Kamora tekanyetso e le 'ngoe ea sodium e' ngoe ea 14C e ngotsoeng ke rabeprazole sodium ka 20 mg, ha ho na moriana o sa fetoloang mokokotlong.

Hoo e ka bang karolo ea 90% ea rabeprazole e epeloa ka liphio haholo ka sebopeho sa metabolites tse peli: conjugate ea mercapturic acid (M5) le carboxylic acid (M6), hammoho le mofuta oa li-metabolites tse peli tse sa tsejoeng tse fumanoeng nakong ea tlhahlobo ea chefo. Karolo e setseng ea sodium ea rabeprazole e nkuoeng e epolloa ka mala.

Ho felisoa ka botlalo ke 99,8%. Lintlha tsena li bonts'a excretion e nyane ea rabeprazole sodium metabolites e nang le bile.

Ho baithaopi ba phetseng hantle, plasma T1 / 2 e ka ba hora e le 'ngoe (ho fapana le lihora tse 0,7 ho isa ho tse 1,5),' me botlalo ba eona ke 3,8 ml / min / kg.

Pharmacokinetics ka lihlopha tse khethehileng tsa bakuli

Ho bakuli ba nang le tšenyo ea sebete e sa foleng, AUC e imena habeli ha e bapisoa le baithaopi ba phetseng hantle, e leng se bontšang ho fokotseha ha metabolism nakong ea "pass ea pele", mme T1 / 2 ho tsoa ho plasma ea mali e eketseha ka makhetlo a 2-3.

Ho bakuli ba nang le ho hloleha ha methapo e tiileng ea pheletsong ba hlokang ho lokisoa ha hemodialysis (CC)

• Bokaholimo bo le bong ba Bilobil bo na le 40 mg ea likhaba tse tsoang makhasi a sefate ginkgo e mebala e 'meli.
• K'hasete e le 'ngoe ea Bilobil Forte e kenyelletsa 80 mg ea monokotšoai makhapetleng a sefate ginkgo e mebala e 'meli.

100 mg ea ntsa e kenyelletsa 19.2 mg ginkgo glycosides mofuta oa flavone le 4.

8 mg terpene lactones mofuta (bilobalides le ginkgolides).

Lintho tse ling: colloidal silicon oxide, starch ea poone, lactose monohydrate, magnesium stearate, talc.

Sebopeho sa Shell: dae oxide e khubelu, titanium dioxide, azorubine, dae oxide oxide, gelatin.

Pharadodynamics

Phytopreparation, normalize metabolism ka har'a lisele rheological matšoao madi le tokafatso ea linama.

E ntlafatsa ho potoloha ha 'mele' me e fana ka kelello tsoekere le oksijenee thibela ho kopana lisele tse khubelu tsa malie hatella ts'ebetso palo ea liplatelete.

E na le litekanyetso tse laolang litekanyetso tsa methapo tsamaisong ea methapo, li kenya ts'ebetso tlhahiso TSIETSI, e ntlafatsa leseli la li-arterioles, e eketsa molumo oa methapo, ka ho etsa joalo e fetola ho tlatsoa ha methapo ea mali. E nyenyefatsa ho fokola ha lebota la sekepe.

Melemo antithrombotic ketso (e matlafatsa lera la lisele tse khubelu tsa mali le liplatelete, e ama biosynthesis li-prostaglandinse fokolisa litlamorao platelet-activating factor) E thibela peroxidation ea mafura a membrane ea lisele le ho etsoa ha li-radicals tsa mahala.

Normalizing metabolism li-neurotransmitters (joalo ka dopamine, norepinephrine le acetylcholine) Hape o na le antihypoxic ketso, e tsosa metabolism, e khothalletsa ho bokella macroergse potlakisa ho lahla tsoekere le oksijenee laola lits'ebetso tsa bobuelli bokong.

Litlamorao

Takatso e theohileng ea mokokotlo, ho nyekeloa ke pelo, bohloko ba ka mpeng, litulo tse otlolohileng, tatso ea tšepe e ka hanong.

Tšebelisano

Matla a fokotsoa ke corticosteroids.

Tekanyetso le tsamaiso

Ka hare, tafole e 1. 2 makhetlo a 3 letsatsi le letsatsi ka mor'a lijo. Sekhahla se phahameng sa letsatsi le letsatsi sa 300 mg ho litekanyetso tse 3 4.

Litlhokahalo tsa polokeho

Litlhokomelo li lokela ho fanoa hammoho le diuretics (haholo-holo tse tsoang ho thiazide).

Ka lebaka la kotsi ea lactic acidosis, tlhahlobo ea mali e lokela ho etsoa likhoeli tse ling le tse ling tse tšeletseng, 'me ts'ebetso ea sebete le ea liphio e lokela ho hlahlojoa. Pele ho buuoa, phetoho ea kalafo ea insulin e ea hlokahala.

Nakong ea kalafo, o ka se noe joala, hobane maemong a mang, ho se mamelle joala ho ka hlaha.

Maemo a polokelo ea lithethefatsi Adebit

Ka mocheso oa kamore.

Qoba hole le bana.

Bophelo ba Shelf ea Adebit ea lithethefatsi

Polelo ea lihlopha tsa nosological

Litaelo tsa Glibutide, litekolo, theko, litlhaloso

Lebitso:

Ketso ea pharmacological:

Ke ea lithethefatsi tse entsoeng ka molomo tse bitsoang hypoglycemic (antidiabetic) (litokisetso tsa molomo tse theolelang tsoekere e tlase) tsa sehlopha sa Biguanide.

Glibutide, joalo ka li-biguanides tse ling, e bua ka lithethefatsi tsa kahare tsa antiidiabetes tse bakang phokotso e kholo ea boima ba 'mele ho bakuli ba nang le lefu la tsoekere ba nang le lefu la tsoekere.

Lithethefatsi tsena li fokotsa takatso ea lijo, li ntlafatsa glencolysis ea anaerobic (tlhahiso ea matla ka seleng ntle le ho nka karolo ha oksijene), e fokotsa ho monya tsoekere e tsoang pampiring ea gastrointestinal, e na le antilipid (e fokotsa likhahla tsa mafura) le phello ea fibinolytic (ho felisoa ha madi a mali).

Matšoao a sebeliso:

E sebelisoa ho phekola lefu la tsoekere la mofuta oa II mellitus (insulin-Independent) ho batho ba baholo.

Hammoho le insulin, e sebelisoa bakeng sa mefuta e thibelang insulin (lefu la tsoekere, e hanyetsanang le kalafo ka litokisetso tsa insulin), hammoho le ho hanyetsa (ho hanyetsa) ho lithethefatsi tsa antidiabetic tsa sulfonylurea, bakeng sa mefuta e bonolo ea lefu la tsoekere, e tsamaeang le botenya, le ho bakuli ba fumanang kalafo ea insulin ka tsoekere e bonolo. lefu la tsoekere (lefu la tsoekere mellitus, le tšoauoang ke phetoho e potlakileng ea tsoekere ea mali).

Mokhoa oa Tiriso:

Abela ka hare ka lijo.

Joaloka moemeli oa lefu la lefu la tsoekere, nka, ho qala ka 0,1 g ka letsatsi (50 mg hoseng le mantsiboea), ho latela phetoho ea tsoekere maling le moroto, lethalinyana le ka eketseha butle-butle ka 50 mg ka letsatsi, empa tekanyetso ea letsatsi le letsatsi ha ea lokela ho feta 300 mg

Litlhoko tsa tlhokomelo hangata hangata li 50-100 mg hoseng le 50 mg ka mantsiboea. Ha e kopantsoe le insulin, tekanyetso ea morao-butle e ea fokotsoa tlasa taolo ea glucose maling le moroto.

Hammoho le litokisetso tsa sulfonylurea, glibutide e beoa maemong a ha ba pele ba sa khone ho fokotsa hyperglycemia (tsoekere e phahameng ea mali) le glucosuria (ho ba teng ha tsoekere ka har'a moroto) ho ea boemong bo hlokahalang. hammoho le anorexigenic / takatso ea lijo / lithethefatsi / lithethefatsi).

Matlapa a nkileng nako e telele a beoa moqolo o le mong oa hoseng (hoseng), butle-butle o eketsa tekanyetso ho matlapa a 4 (hoseng le mantsiboea ka mor'a ho ja).

Liketsahalo tse sa thabiseng:

Glibutide e mamelleha hantle, empa ho lahleheloa ke takatso ea lijo, ho nyekeloa, ho hlatsa, lets'ollo (lets'ollo), le tatso ea tšepe e molomong li ka bonoa. Hamorao ka mor'a ho qala kalafo (kamora khoeli kapa ho feta), bofokoli, ho fokotsa boima ba 'mele hoa khoneha.

Litla-morao hangata li tloha kapele ka phokotso ea litekanyetso kapa ho tlohela lithethefatsi.

Contraindication:

Contraindication mabapi le ts'ebeliso ea glibutide ke: matšoao a felletseng a ts'ebeliso ea insulin, ho ba sieo ha mmele oa endo native (ho thehiloe 'meleng) kapa ho tsamaisoa ka mokhoa o kantle (ka ntle) insulin, komisi (ho felloa ke kelello, ho bontšoa ke ho se sebetse hantle hoa ts'ebetso ea mmele ho susumetso ea kantle), acidosis (acidization), mafu a tšoaetsanoang, albinuria (protheine ka har'a moroto) ka lebaka la lefu la tsoekere (ho senya methapo ea mali le lisele tsa meno ho lefu la tsoekere), tšenyo ea sebete, angiopathy ea lefu la tsoekere. molumo oa methapo ea mali o amanang le tsoekere e phahameng ea mali) ka monyetla oa ho qala ts'ebetso ea ho ruruha, mokokotlo oa maemo a feteletseng, boimana .. Ho lokela ho hopoloa hore bakuli ba bang ba ka nts'etsapele ketosis ka glibutide (acidization ka lebaka la litaba tse ngata tsa 'mele oa ketone maling - lihlahisoa tse mahareng metabolism) ka ho fokotseha ha alkalinity ea mali (ts'ebetso ea sistimi ea mali e sebelisang mali, e thibelang phetoho ea pH).

Haeba ketosis e hlaha, moriana o felisitsoe. Ha u phekola ka glibutide, haholo-holo nakong ea pele, ho hlokahala hore u hlahlobe moroto bakeng sa litaba tsa acetone ho eona. Nakong e tlang, boikemisetso ba 'mele oa ketone (lihlahisoa tse bohareng tsa metabolic) bo etsoa nako e ka bang 1 ka beke.

Sebopeho sa tlhahiso ea sehlahisoa:

Matlapa a 0,05 g, ka har'a sephutheloana sa likotoana tse 50. Matlapa a nkileng nako e telele a buformin retard.

Maemo a polokelo:

Setlhare se tsoa lenaneng B. Sebakeng se omileng.

Buformin hydrochloride, Adebit, Butyl biguanide, Gliporal, Glibigid hydrochloride, Krebon, Silubin.

Butylbiguanide hydrochloride. White phofo ea kristale e tsoekere.Ho qhibilihisoa habonolo ka metsing le joala. Letlapa le le leng la ketso ea mofuta oa nako e telele (ea nako e telele) le na le: 0.17 g ea buformin tosylate, e tsamaellanang le 0,1 g ea ntho e sebetsang (glibutide).

Litokisetso tsa ketso e ts'oanang:

Diaformin (Diaformin) Glucovans (Glucovance) Oltar (Oltar) Glyukofazh (Glucophage) Maninil (Maninil)

Ha ua fumana tlhaiso-leseling eo u e hlokang?
Litaelo tse felletseng tsa lithethefatsi "glibutide" li ka fumanoa mona:

Lingaka tse ratehang!

Haeba u na le boiphihlelo ba ho fana ka moriana ona ho bakuli ba hau - arolelana sephetho (tlohela maikutlo)! Na moriana ona o thusitse mokuli, na ho bile le litla-morao life nakong ea kalafo? Phihlelo ea hau e tla khahla basebetsi-'moho le uena hammoho le bakuli.

Bakuli ba ratehang!

Haeba moriana ona o ne o reretsoe meriana ena 'me u bile le tlhahlobo ea kalafo, mpolelle hore na e ea sebetsa (hore na ea thusa), ho na le litla-morao, tseo u li ratang / tseo u sa li rateng. Batho ba likete ba batla tlhahlobo ea marang-rang ea meriana e fapa-fapaneng. Empa ke ba fokolang feela ba ba siileng. Haeba uena ka bouena u sa tlohele maikutlo ka taba ena - ba bang kaofela ha ba na seo ba ka se balang.

Ke leboha haholo!/ sitemap-index.xml

Tlhaloso ea meriana "Adebit"

Ketso ea pharmacological e fokotsa tsoekere ea mali le ho feto-fetoha ha eona ha letsatsi le letsatsi, tlhoko ea insulin.

Matšoao a ho sebelisoa

• Type II lefu la tsoekere mellitus (hammoho le lintho tse tsoang ho sulfonylurea), botenya bo bongata ba tsoekere, metabolism e sa tsitsang ea tsoekere (hammoho le insulin).

• Matlapa a 50 mg
• blister 20, lebokose (lebokose) 2.

Pharmacodynamics ea moetsi oa lithethefatsi Hypoglycemic bakeng sa tsamaiso ea molomo ho tsoa sehlopheng sa li-biguanides. E na le tšusumetso e tobileng ea glycolysis ea anaerobic ho lithane tsa pherekano.

E hatella gluconeogeneis ka har'a sebete, e fokotsa ho monya ha tsoekere maling ka mpeng (e thibella alpha-glycosidases ea mala, e fokotsa ho phatloha ha enzymatic ea di-, oligo- le polysaccharides ho monosaccharides), e fokotsa takatso ea lijo.

E fokotsa dikahare tsa lero la plasma glucagon, e phahamisa maikutlo a lisele tsa ho kenella ka har'a insulin ho li-insulin receptors. Ho qala ha ts'ebetso ke kamora lihora tse 2-4, nako ea ts'ebetso e ka ba lihora tse 8.

Contraindication

• Hypersensitivity, ketonuria, hyperglycemic coma, hypoglycemia, ho ima, ho nyeka. Lactic acidosis (ho kenyelletsa le nalane)
• hepatic le / kapa ho hloleha ha renal, CHF, ho hloleha ho phefumoloha, ho ruruha ho matla ha myocardial, ho lemalla joala bo sa foleng, feberu, mafu a tšoaetsanoang, albinuria khahlano le semelo sa lefu la tsoekere, lefu la tsoekere.

Litla-morao: Ho fokotseha takatso ea lijo, ho nyekeloa ke pelo, ho hlatsa, ho fokola, ho theola boima ba 'mele, gastralgia, lactic acidosis, lets'ollo, tatso ea "tšepe" molomong, le lintho tse ling tse sa sebetseng hantle.

Tekanyetso ka hare, Letlapa le le leng. Makhetlo a 2-3 ka letsatsi ka mor'a lijo. Tekanyetso e kholo ea letsatsi le letsatsi ke 300 mg ho tekanyetso ea 3-4.

Matšoao a Kakaretso ea Litaba tsa ho fetela ka bongata: hypoglycemia, hypoglycemic coma.

Ho sebelisana le lithethefatsi tse ling Phello ea hypoglycemic e fokotsoa ke melemo ea phenothiazine, corticosteroids, lihormone tse susumetsang tsa qoqotho, li-estrogens, diuretics, li-inhibitors tsa MAO, salicylates.

Litaelo tse ikhethileng tsa ho amoheloa hoa hlokahala ho hlokomela khafetsa tlhahiso ea tsoekere ea ka mehla moriring, boemo ba glycemia. Ha o kenella kalafo le buformin, tekanyetso ea insulin e fokotseha butle butle.

Maemo a polokelo B: Ka mocheso oa kamore.

Bophelo ba Shelf likhoeli tse 60.

Litlelase tsa mafu

Mellitus e sa itšetleheng ka insulin

Sehlopha sa sehlopha sa ATX (ATC)

Phekolo ea lijo le tsamaiso ea methapo

Ketso ea pharmacological

Tlhaloso Hypoglycemic effect e etselitsoe ho theola maemo a tsoekere ea mali. Mochine oa ts'ebetso o ipapisitse le tlamo ea insulin ho li-receptor tsa eona, ka tsela eo e ama metabolism ea glucose.

Ka lebaka leo, boemo ba tsoekere maling bo fokotseha ka lebaka la keketseho ea ts'ebeliso ea eona lithong tsa pherekano, haholo mesifa ea marapo le lithane tsa adipose, le thibelo ea ho etsoa ha tsoekere maling.

Ntle le phello e tobileng ea insulin, mochine oa ts'ebetso o tsamaisana le ho hlohlelletsa pancreatic? Lisele, tse tsamaeang le ts'usumetso le keketseho e nyolohileng ea "insulin" ea insulin, ka ho tlama ho li-receptors tse ikhethileng (tse amanang le liteishene tsa potasiamo tsa potasiamo tsa ATP) ho? Lisele.

Hape, ts'ebetso ea ts'ebetso e ka amahanngoa le thibelo ea gluconeogeneis ka har'a sebete (ho kenyelletsa le glycogenolysis) le ts'ebeliso e matla ea tsoekere ka tisketso ea mothapo, thibelo ea ts'ebetso ea insulin le ntlafatso ea ho tlama ha eona ho li-insulin receptors (hona ho eketsa tsoekere ea glucose le metabolism ea eona).

O mong oa mehato ea ts'ebetso ke ho fokotsa ho hanyetsa ha insulin liseleng tse poteletseng le sebete. Ho thibela ho phatloha ha poly- le oligosaccharides hoa khoneha, e leng ho fokotsang sebopeho le ho monya ha tsoekere ka mpeng, ka tsela eo, e thibela nts'etsopele ea hypprobial hyperglycemia. Lithethefatsi tsa Hypoglycemic li sebelisetsoa ho phekola lefu la tsoekere.

Sehlopha sa mahlale

Hypoglycemic synthetic le li-agents tse ling

Lintho tse sebetsang

Litlhaloso tse tšoeu tsa kristale e tsoekere. Qhibiliha habonolo ka metsing le joala.

Lintlha tse fanoeng ke tsa tlhaiso-leseling feela.
Pele u sebelisa, ka kopo ikopanye le setsebi.

Ho thusang Bilobil: litaelo le litlhahlobo

Pheko ea tlhaho ea Bilobil ke sebopeho sa kelello.

E ikemiselitse ho ntlafatsa ts'ebetso ea boko le tsamaiso ea methapo. E entsoe motheong oa limela tsa boikoetliso ba boikoetliso bo tsoang sehlopheng sa li-ginkgo tse mebala e 'meli. Mofuta ona oa li-conifers o tsoa bochabela ho Chaena, empa o lengoa lirapeng tse ngata tsa lefats'e tsa limela.

Leqepheng lena o tla fumana leseli lohle mabapi le Bilobil: litaelo tse felletseng tsa ts'ebeliso ea lithethefatsi ena, litheko tse tloaelehileng mefuteng ea meriana, hammoho le litlhahlobo tsa batho ba seng ba sebelisitse Bilobil. U batla ho tlohela maikutlo a hau? Ka kopo ngola maikutlo.

Sehlopha sa tliliniki le meriana

Sethethefatsi se ntlafatsang ho potoloha ha 'mele le ho potoloha.

Lipehelo tsa Khefu ea Litlama

E lokolloa ntle le lengolo la ngaka.

Bilobil e bokae? Theko e tloaelehileng literekeng tsa litlama e boemong ba li-ruble tse 550.

Sokolla foromo le sebopeho

Li-capsules tse sootho tsa 'mala o sootho. Li-capsules li na le phofo ea tan e nang le likaroloana tse hlakileng tse lefifi.

• K'hasete e le 'ngoe e na le ntho e sebetsang: Ho omisoa hoa makhasi a ginkgo biloba - 40 mg, e lekantsoeng hore e be le 9.6 mg ea flavono glycosides ea ginkgo le 2.4 mg ea terpene lactones (ginkgolides le bilobalides) ho 40 mg.
• Lihlahisoa, lactose monohydrate, starch ea poone, talc, anhydrous colloidal silicon dioxide, magnesium stearate.
• Khetla ea Capsule: gelatin, indigotine (E132), azorubine (E122), oxide e khubelu ea tšepe * (E172), oxide oxide e ngata (E 172), titanium dioxide (E 171).

Phello ea pharmacological

Bilobil ke angioprotector ea semela. Ka lebaka la taba ea hore motsoako oa moriana o kenyelletsa ginkgo biloba extract, e leng terpene lactones le flavone glycosides, likarolo tsa eona tse sebetsang li matlafatsa haholo le ho phahamisa bokhoni ba marako a methapo ea mali, hammoho le ho ntlafatsa bokhoni ba rheological ba mali.

Litaelo tsa Bilobil li boetse li bonts'a hore lithethefatsi li laola ka nepo phello e itšetlehileng ka lethathamo tsamaisong ea pelo le methapo, li eketsa molumo oa methapo, li laola ts'ebetso ea ho tlatsa methapo ea mali ka mali, mme e hlapolla methapo e meholo ea methapo.

Matšoao a ho sebelisoa

Bilobil e fuoe li-pathologies tse ngata tsa tsamaiso ea methapo, hammoho le matšoao a fapaneng le syndromes, har'a tsona:

• Matšoenyeho
• Tinnitus.
• Ho hloka boroko
• Dyscirculatory encephalopathy, haholo-holo ka ho se sebetse hantle.
• Dizziness, haholo-holo e bakoang ke lisosa tsa vascular.
• Fokotsa nako ea tlhokomelo.

Bilobil e ka sebelisoa hape kalafong e rarahaneng ha ho e-na le mathata a potoloha ka har'a likepe tsa libaka tse tlase (tloaelo ea angiosurgery).

Contraindication

Hangata lithethefatsi li mamelloa hantle ke bakuli, leha ho le joalo, maemong a ikhethileng, nts'etsopele ea litla-morao tse joalo e ile ea hlokomeloa:

• Ho tloha tsamaisong ea methapo e bohareng: ho opeloa ke hlooho, ho teneha ho eketsehileng.
• Litla-morao:
• Ho tsoa ho ts'ilo ea lijo: ho nyekeloa pelo, ho hlatsa, setofo se holofetseng.

Ka nts'etsopele ea maikutlo a tebileng a ho kula, ho tlosoa hoa lithethefatsi hoa hlokahala.

Nts'etsopele ea litla-morao e ne e bonoa hangata ha ho nooa moriana Bilobil Intens, hammoho le ho bakuli ba tsofetseng ba nang le tekanyetso e phahameng ea lithethefatsi.

Bokhachane le pelehi

Ka lebaka la khaello ea tlhaiso-leseling e lekaneng ea bongaka, Bilobil ha e khothalletsoe ho sebelisoa nakong ea kemaro le nakong ea ho anyesa.

Litaelo tsa ho sebelisoa

Litaelo tsa tšebeliso li bontša hore Bilobil o nkuoa ka molomo. K'habeche e lokela ho metsoa ka metsi a mangata, ho sa tsotelehe lijo.

1. Dyscirculatory encephalopathy ea li-etiologies tse fapaneng: likhahla tse 1-2. Makhetlo a 3 / ka letsatsi
2. Mathata a amanang le ho hlaseloa ke letsoele (chizeloselese, tinnitus, hypoacusia), senile macular degeneration, retinopathy ea lefu la tsoekere: li-1. Makhetlo a 3 / ka letsatsi
3. Tšitiso ea ho potoloha ha mali le phallo ea mali ka bongata (ho kenyelletsa le arteryopathy ea maoto le matsoho), lefu la Raynaud: 1 li-cap. Makhetlo a 3 / ka letsatsi

Matšoao a pele a ntlafatso a hlaha hangata kamora khoeli e le 'ngoe. Nako ea phekolo ke bonyane likhoeli tse 3 (haholo-holo ho bakuli ba tsofetseng). Thupelo ea bobeli e ka etsahala kamora ho buisana le ngaka.

Litlamorao

Ho nwa moriana ho ka baka litlamorao tse latelang: ho tsekela, ho nyekeloa, ho hlatsa, ho opeloa ke hlooho, ho ruruha, lekhopho la letlalo, ho hlohlona, ​​kutlo le ho se bone hantle, tšupa ea mali ea ka mpeng, khaello ea mali le ho hloka boroko.

Maemong a mang, bilobil e ka baka ho tsoa madi le hemorrhege bokong. Sena se sebetsa haholo maemong ha moriana o nooa hammoho le lihokelo tsa mali. Ka kakaretso, litla-morao tsa moriana li bonoa hangata ebile ke tsa nakoana. Leha ho le joalo, haeba li etsahala, o lokela ho etela ngaka hang-hang.

Bongata

Haeba palo e fetisitsoe, litlamorao tsa karabelo e mpe li ka ntlafatsoa. Phekolo ke ea setso, ho latela matšoao.

Litaelo tse khethehileng

Phello ea kalafo ea lithethefatsi e hlaha kamora nako e ka bang khoeli e le ngoe ea ho sebelisa moriana. Haeba nakong ea phekolo ea lithethefatsi ho na le ho senyeha ka tšohanyetso, tahlehelo ea kutlo, tinnitus kapa ho tsekela ho hlaha, o tlameha ho khaotsa ho sebelisa lithethefatsi mme o batle keletso ea bongaka ka potlako.

Ha ho kgothaletswe ho khetha Bilobil ho bakuli ba nang le galactose kapa glucose malabsorption syndrome, congenital galactosemia kapa bofokoli ba congenital lactase, hobane lactose ke karolo ea eona.

Ho sebelisana le lithethefatsi

Bilobil ha ea lokela ho laeloa bakuli ba tloaetseng ho sebelisa lithethefatsi tse theolelang ho fokotseha ha mali (mohlala, acetylsalicylic acid le litlhare tse ling tse seng khahlanong le ts'oaetso tsa antiidal, anticoagulants e tobileng le e sa tobang. Motsoako ona o ka eketsa menyetla ea ho tsoa mali ka lebaka la ho lelefala ha nako ea ho soetseha.

Re nkile maikutlo a batho mabapi le lithethefatsi Bilobil:

1. Tshepo Kamora hore ho nkuoe methapo ea methapo ea kutlo ea mali le methapo ea mali bokong, Bilobil Forte o laetse ngaka, e noele hoo e ka bang selemo mme e sa utloisise hore na hobaneng khatello e ba tlase le 10070, mme e etsahetse le tlase, mme pulse ea tlolela ho 120, a ikutloa a le mobe haholo, a tlohela ho nwa mme hanyane ka hanyane tsohle tsa eba ho fola, e le hore e mong a fole mme e mong a holofetse, o hloka ho ba hlokolosi haholo ka moriana ona. Bophelo bo botle ho bohle.
2. Galina. O ile a noa khoeli ka mafolofolo, a lokolloa ho cervical osteochondrosis. Hlooho ke pono e koahetsoeng ke maru.Ha ho a thusa letho.
3. Olga Ke ile ka nka li-capsules kamora ho hlaseloa ke stroke ho khothaletso ea ngaka ho tlosa litlamorao tse mpe. "Bilobil" e thusitse ho tlosa tinnitus le memori e ntlafalitsoeng.
4. Zina. Ho theko e boima haholo ha ho bolele ho betere! Bilobil Intens 120mg: pakete ea li-capsules tse 60 e bitsa li-ruble tse 970, theko ea tanakan 40mg bakeng sa matlapa a 90 a 1580, ha tanakan e sa nthuse, mme likhahla tsa Bilobil li ile tsa nyoloha. Mathata a ho hopola a hloka tharollo ka mokhoa oa sethethefatsi sa boleng bo holimo, se tšepahalang. Bilobil Intensity e ile ea phekoloa mme ha ke sa na bothata ba ho hopola. Mme hlooho ha e peteke, ha e utloe bohloko. Empa ntho ea bohlokoa ke hore ka hlooho e hlakileng ho bonolo haholoanyane ho sebetsa le ho etsa lintho tsa letsatsi le letsatsi.
5. Olya. Ke ile ka noa thupelo ea likhoeli tse tharo ea bilobil intens. Ho ikutloa o le motle. Hlooho ea ka e ile ea khanya, ho bonolo ho nahana, ke hopola ntho e ngoe le e ngoe 'me ha ke ferekanye letho. Maikutlo a sa thabiseng a kang ho tsekela a felile, 'me bokhoni ba ho lemoha bo eketsehile joaloka bongoaneng. Bilobil o molemo ho feta lithethefatsi tse ngata tse nang le ginkgo, sena ke setlhare, eseng se sebe, sa tlhaho ebile se matla, ka hona ke ikutloa ke le moholo. Pele o ne a noa ginkoom, empa ha ho na litholoana. Kamora ho koenya, ke fetela bobe bohle. Mme Bilobil ke sethethefatsi. E lokela chelete ka kotloloho.

Lingaka tse ngata li fana ka bopaki ba hore ho rengoa ha sefate sa ginkgo ke sona feela setlhare se ntlafatsang ts'ebeliso ea kelello ho bakuli ba tsofetseng. Leha ho le joalo, liphuputso li boetse li bontšitse hore kamora ho khaoloa ha Bilobil ho bakuli ba sehlopha sena, ho khutla hoa matšoao a amanang le lilemo ho a bonoa.

Manonyeletso a meriana ke meriana Bilobil, Vitrum Memori, Gingium, Ginos, Memoplant le Tanakan.

Li-analogues tsa Bilobil ke lithethefatsi tse kang:

• Memantine
• Memorel,
• Noojeron
• Akatinol Memantine,
• Alzeym
• Intellan
• Memaneirin
• Memorant
• Maruks
• Memantinol
• Memikar.

Pele u sebelisa li-analogues, etela ngaka ea hau.

Maemo a polokelo le bophelo ba sehatsetsing

Setlhare sena se loketse ho sebelisoa lilemo tse tharo. Se ke oa fana ka monyetla oa ho bana, sireletsa ho tloha leseli. Mocheso oa polokelo 200C.

Sehlopha sa tliliniki le meriana

Inhibitor ea H + -K + -ATPase. Lithethefatsi tsa antiulcer

Fomu ea tokollo, sebopeho le sephutheloana

◊ Li-capsules tsa Enteric gelatin e thata, saese ea 3, e nang le 'mele o mosoeu le' mala o moputsoa, ​​litaba tse ka har'a likhapetla tsena li ngotsoe ka bophara ho tloha ho bosoeu ho isa ho bosoeu ka tisi e bolila kapa e putsoa.

* rabeprazole, pellet ntho 8,5% - 118 mg.

Baeti: libaka tsa tsoekere (sucrose - 99.83%, povidone - 0,17%) - 71.46 mg, sodium carbonate - 1,66 mg, talc - 1.77 mg, titanium diode - 0,83 mg, hypromellose - 14,75 mg.

Ba hlahisang likhetla tsa pellet: hypromellose phthalate - 15.94 mg, joala ba cetyl - 1.59 mg.
Karolo ea khalase ea lebili le thata ea gelatin 3: setopo sa capsule - titanium dioxide - 2%, gelatin - ho fihla ho 100%, capule cap - titanium dioxide - 2%, dae e putsoa e nang le patsi - 0,0176%, dae e ntšo ea daemane - 0,0051%, gelatin - ho fihla 100%.

Li-pcs tse 5. - Liphutheloana tsa blister (1, 2, 3) - lipakete tsa karete. - Liphutheloana tsa blister (1, 2, 3) - lipakete tsa karete ea likarete. 10 likhomphutha. - Liphutheloana tsa blister (1, 2, 3) - lipakete tsa karete.

14 li-PC. - Liphutheloana tsa blister (1, 2, 3) - mekotla ea likarete tse 15 likhomphutha. - Liphutheloana tsa blister (1, 2, 3) - mekotla ea likarete tse 20 likhomphutha tse 20. - Liphutheloana tsa blister (1, 2, 3) - lipakete tsa karete.

Li-pcs tse 30 - Liphutheloana tsa blister (1, 2, 3) - lipakete tsa karete.

Ketso ea pharmacological

Inhibitor ea H + -K + -ATPase. Lithethefatsi tsa antiulcer.

Rabeprazole sodium ke ea sehlopha sa likhomphutha tsa antisecretory tse tsoang benzimidazole. Rabeprazole sodium e thibela secretion ea lero la sefuba ka ho thibela H + / K + -ATPase ka lekunutu la lisele tsa parietal tsa mpa.

H + / K + -ATPase ke mochine o rarahaneng o sebetsang joaloka pompo ea proton, ka hona, rabeprazole sodium ke inhibitor ea pampiri ea proton ka mpeng mme e thibela karolo ea ho qetela ea tlhahiso ea acid.

Phello ena e itšetlehile ka tekanyetso mme e lebisa ho ho hatelloa ka bobeli ka basal le ho susumetsoa ha secretion ea acid, ho sa tsotelehe ho khopisa. Sodium ea Rabeprazole ha e na thepa ea anticholinergic.

Kamora ho tsamaisoa ha molomo oa sodium ea rabeprazole ka tekanyo ea 20 mg, phello ea antisecretory e hlaha ka nako ea hora e le ngoe.Thibelo ea basal le e hlohlellelitsoeng acid e secretion lihora tse 23 ka mor'a ho nka tekanyetso ea pele ea sodium ea rabeprazole ke 69% le 82%, ka ho latellana, 'me e nka lihora tse 48.

Nako ena ea ketso ea pharmacodynamic e feta hole le e boletsoeng esale pele ke T1 / 2 (hoo e ka bang hora e le 'ngoe). Phello ena e ka hlalosoa ka ho tlama ha nako e telele hoa lithethefatsi ho H + / K + -ATPase ea lisele tsa parietal tsa mpa.

Boleng ba phello ea inhibitory ea rabeprazole sodium ho secretion ea acid e fihla sehlabeng kamora matsatsi a 3 a ho nka sodium ea rabeprazole. Ha o emisa ho etsa ts'ebetso ea sekhukhu e ea khutlisoa matsatsing a 1-2.

Kameho ea ho tebeloa ha gastrin ho plasma ea mali

Litekong tsa bongaka, bakuli ba ile ba nka sodium ea rabeprazole ka tekanyetso ea 10 kapa 20 mg letsatsi le letsatsi bakeng sa nako ea kalafo e ka bang likhoeli tse 43. Keketseho ea gastrin plasma ea mali e ile ea eketseha bakeng sa libeke tse 2-8 tsa pele, tse bonts'ang phello ea inhibitory ho secretion ea acid. Ts'oaetso ea gastrin e khutletse boemong ba eona ba pele, hangata kamora libeke tse 1-2 kamora ho khaotsa kalafo.

Kameho ho lisele tse kang enterochromaffin

Ha ho hlahlojoa mehlala ea "biopsy" ea motho ka mpeng ho tsoa mokokotlong le ka tlase ho mpa, bakuli ba 500 ba amohetseng rabeprazole sodium kapa setlhare sa papiso bakeng sa libeke tse 8, liphetoho tse tsitsitseng mo sebopeho sa morphological sa lisele tse tšoanang le enterochromin, ho teba ha gastritis, khafetsa ha atrophic gastritis, metaplasia ea methapo kapa ho ata ha Helicobacter. hlokometsoe.

Phuputsong ea bakuli ba fetang 400 ba fumaneng rabeprazole sodium (10 mg / letsatsi kapa 20 mg / letsatsi) ho fihlela selemo se le seng, liketsahalo tsa hyperplasia li ne li le tlase ebile li bapisoa le seo bakeng sa omeprazole (20 mg / kg). Ha ho na linyeoe tsa liphetoho tse makatsang kapa lihlahala tsa nama ea mokokotlo tse bonoang litekong.

Liphetho tsa systemic tsa rabeprazole sodium mabapi le tsamaiso ea methapo e bohareng, tsamaiso ea methapo ea pelo kapa ea ho hema ha e sa fumanoa.

Ho ile ha bontšoa hore sodium ea rabeprazole, ha e nooa ka molomo ka tekanyetso ea 20 mg bakeng sa libeke tse 2, ha e ame ts'ebetso ea qoqotho, metabolism ea carbohydrate, khatello ea li-parathyroid hormone maling, hammoho le khatello ea cortisol, estrogen, testosterone, prolactin, glucagon, FSH, LH , renin, aldosterone le hormone ea kholo.

Mofumahali

Tlhahiso le kabo

Rabeprazole e kenella ka potlako ka popelong, Cmax e plasma ea mali e fihlella lihora tse ka bang 3.5 ka mor'a tsamaiso ka tekanyo ea 20 mg. Liphetoho ho Cmax ho plasma ea mali, litekanyetso tsa AUC tsa rabeprazole li kahare ho litekanyetso ho tloha ho 10 ho isa ho 40 mg.

Boaoavailability e felletseng ka mor'a taolo ea molomo ka tekanyo ea 20 mg (bapisoa le iv) e ka ba 52%. Ntle le moo, bioavailability ha e fetohe ka litekanyetso tse ngata tsa rabeprazole. Leha e le nako ea ho sebelisa lithethefatsi motšehare, kapa tsamaiso e tšoanang ea li-antacid ha e ame ho amoheloa ha rabeprazole.

Ho nka lithethefatsi ka lijo tse nang le mafura ho fokotsa ho kenngoa ha rabeprazole lihora tse 4 kapa ho feta, leha ho le joalo, Cmax kapa boemo ba ho fetoloa ha bo fetole.

Ho tlangoa ha rabeprazole ho liprotheine tsa plasma hoo e ka bang 97%.

Metabolism le excretion

Metabolite e ka sehloohong ke thioether (M1). Metabolite e le 'ngoe feela e sebetsang ke desmethyl (M3), leha ho le joalo, e ne e ikemiselitsoe ka khatello e tlase ho karolo ea morupeluoa a le mong feela ea thuto ka mor'a ho nka rabeprazole ka tekanyo ea 80 mg.

Kamora tekanyetso e le 'ngoe ea sodium e' ngoe ea 14C e ngotsoeng ke rabeprazole sodium ka 20 mg, ha ho na moriana o sa fetoloang mokokotlong.

Hoo e ka bang karolo ea 90% ea rabeprazole e epeloa ka liphio haholo ka sebopeho sa metabolites tse peli: conjugate ea mercapturic acid (M5) le carboxylic acid (M6), hammoho le mofuta oa li-metabolites tse peli tse sa tsejoeng tse fumanoeng nakong ea tlhahlobo ea chefo. Karolo e setseng ea sodium ea rabeprazole e nkuoeng e epolloa ka mala.

Ho felisoa ka botlalo ke 99,8%. Lintlha tsena li bonts'a excretion e nyane ea rabeprazole sodium metabolites e nang le bile.

Ho baithaopi ba phetseng hantle, plasma T1 / 2 e ka ba hora e le 'ngoe (ho fapana le lihora tse 0,7 ho isa ho tse 1,5),' me botlalo ba eona ke 3,8 ml / min / kg.

Pharmacokinetics ka lihlopha tse khethehileng tsa bakuli

Ho bakuli ba nang le tšenyo ea sebete e sa foleng, AUC e imena habeli ha e bapisoa le baithaopi ba phetseng hantle, e leng se bontšang ho fokotseha ha metabolism nakong ea "pass ea pele", mme T1 / 2 ho tsoa ho plasma ea mali e eketseha ka makhetlo a 2-3.

Ho bakuli ba nang le ho hloleha ha methapo e tiileng ea pheletsong ba hlokang ho lokisoa ha hemodialysis (CC)

• Bokaholimo bo le bong ba Bilobil bo na le 40 mg ea likhaba tse tsoang makhasi a sefate ginkgo e mebala e 'meli.
• K'hasete e le 'ngoe ea Bilobil Forte e kenyelletsa 80 mg ea monokotšoai makhapetleng a sefate ginkgo e mebala e 'meli.

100 mg ea ntsa e kenyelletsa 19.2 mg ginkgo glycosides mofuta oa flavone le 4.

8 mg terpene lactones mofuta (bilobalides le ginkgolides).

Lintho tse ling: colloidal silicon oxide, starch ea poone, lactose monohydrate, magnesium stearate, talc.

Sebopeho sa Shell: dae oxide e khubelu, titanium dioxide, azorubine, dae oxide oxide, gelatin.

Fomu ea tokollo

Li-capsules tsa pinki tsa galatin, ka hare li na le phofo e sootho e nang le likaroloana tse bonahalang tse lefifi. Li-capsules tse 10 ka blister, lilomo tse peli kapa tse tšeletseng ka har'a pakete ea karete.

Ketso ea pharmacological

Neurometabolic, antihypoxice ntlafatsang ho ikatisa, ho ntlafatsa ho potoloha le ho potoloha ha lisele, angioprotective, antioxidant ketso.

Pharmacodynamics le pharmacokinetics

Pharadodynamics

Phytopreparation, normalize metabolism ka har'a lisele rheological matšoao madi le tokafatso ea linama.

E ntlafatsa ho potoloha ha 'mele' me e fana ka kelello tsoekere le oksijenee thibela ho kopana lisele tse khubelu tsa malie hatella ts'ebetso palo ea liplatelete.

E na le litekanyetso tse laolang litekanyetso tsa methapo tsamaisong ea methapo, li kenya ts'ebetso tlhahiso TSIETSI, e ntlafatsa leseli la li-arterioles, e eketsa molumo oa methapo, ka ho etsa joalo e fetola ho tlatsoa ha methapo ea mali. E nyenyefatsa ho fokola ha lebota la sekepe.

Melemo antithrombotic ketso (e matlafatsa lera la lisele tse khubelu tsa mali le liplatelete, e ama biosynthesis li-prostaglandinse fokolisa litlamorao platelet-activating factor) E thibela peroxidation ea mafura a membrane ea lisele le ho etsoa ha li-radicals tsa mahala.

Normalizing metabolism li-neurotransmitters (joalo ka dopamine, norepinephrine le acetylcholine) Hape o na le antihypoxic ketso, e tsosa metabolism, e khothalletsa ho bokella macroergse potlakisa ho lahla tsoekere le oksijenee laola lits'ebetso tsa bobuelli bokong.

Mofumahali

Kamora ho nka bioavailability bilobalida le ginkgolides ke 85%. Ts'isinyo e phahameng ka ho fetisisa e tlalehiloe lihora tse peli kamora ho sebelisa moriana. Ho felisoa ha halofo ea bophelo ke lihora tse 4-10. Limolek'hule tsa lintho tsena ha li senyehe 'meleng' me li huleloa ka botlalo ka moroto, ho isa tekanyong e nyane - ka makhopho.

Matšoao a ho sebelisoa

• Ho potoloha ka bongata le ho potoloha ha mali, Lefu la Raynaud.

Discirculatory encephalopathy ka lebaka la stroke, ho sithabela maikutlo, lilemo le lisosa tse ling, tse tsamaeang le ho fokolisa mohopolo, tlhokomelo, ho fokotseha hoa bokhoni ba kelello, phetoho ea mekhoa ea ho robala.

Contraindication

• Lefu la ho ruruha.
• Fokotsa coagulability.
• Kotsi ea bokuli bo amanang le "cerebrovascular".
• Alsa ea Peptic mokhatlong o boima.
• Myocardial infarction.
• Sensitization ho likarolo tsa moriana.
• Lilemo ho isa ho lilemo tse 18.

Litlamorao

• Lintho tse amanang le tšebetso ea methapo: ho hloka boroko, hlooho e bohlokoho se utloe hantle litsebeng.

Lipapole (matlapa) Bilobil, litaelo tsa tšebeliso

Ho discirculatory encephalopathy sebelisa li-capsules tsa 1-2 makhetlo a mararo ka letsatsi.

Ka kalafo tlolo ea molaomicrocirculation le potoloho ea potoloho, Lefu la Raynaud nka sekotlolo se le seng makhetlo a mararo ka letsatsi.

Ho lefu la tsoekere, retinopathylilemo dnchafatso ea macular ho khothaletsa 1 capsule makhetlo a mararo ka letsatsi.

Bongata

Haeba palo e fetisitsoe, litlamorao tsa karabelo e mpe li ka ntlafatsoa. Phekolo ke ea setso, ho latela matšoao.

Litaelo tse khethehileng

Phello ea kalafo ea lithethefatsi e hlaha kamora nako e ka bang khoeli e le ngoe ea ho sebelisa moriana. Haeba nakong ea phekolo ea lithethefatsi ho na le ho senyeha ka tšohanyetso, tahlehelo ea kutlo, tinnitus kapa ho tsekela ho hlaha, o tlameha ho khaotsa ho sebelisa lithethefatsi mme o batle keletso ea bongaka ka potlako.

Ha ho kgothaletswe ho khetha Bilobil ho bakuli ba nang le galactose kapa glucose malabsorption syndrome, congenital galactosemia kapa bofokoli ba congenital lactase, hobane lactose ke karolo ea eona.

Ho sebelisana le lithethefatsi

Bilobil ha ea lokela ho laeloa bakuli ba tloaetseng ho sebelisa lithethefatsi tse theolelang ho fokotseha ha mali (mohlala, acetylsalicylic acid le litlhare tse ling tse seng khahlanong le ts'oaetso tsa antiidal, anticoagulants e tobileng le e sa tobang. Motsoako ona o ka eketsa menyetla ea ho tsoa mali ka lebaka la ho lelefala ha nako ea ho soetseha.

Re nkile maikutlo a batho mabapi le lithethefatsi Bilobil:

1. Tshepo Kamora hore ho nkuoe methapo ea methapo ea kutlo ea mali le methapo ea mali bokong, Bilobil Forte o laetse ngaka, e noele hoo e ka bang selemo mme e sa utloisise hore na hobaneng khatello e ba tlase le 10070, mme e etsahetse le tlase, mme pulse ea tlolela ho 120, a ikutloa a le mobe haholo, a tlohela ho nwa mme hanyane ka hanyane tsohle tsa eba ho fola, e le hore e mong a fole mme e mong a holofetse, o hloka ho ba hlokolosi haholo ka moriana ona. Bophelo bo botle ho bohle.
2. Galina. O ile a noa khoeli ka mafolofolo, a lokolloa ho cervical osteochondrosis. Hlooho ke pono e koahetsoeng ke maru. Ha ho a thusa letho.
3. Olga Ke ile ka nka li-capsules kamora ho hlaseloa ke stroke ho khothaletso ea ngaka ho tlosa litlamorao tse mpe. "Bilobil" e thusitse ho tlosa tinnitus le memori e ntlafalitsoeng.
4. Zina. Ho theko e boima haholo ha ho bolele ho betere! Bilobil Intens 120mg: pakete ea li-capsules tse 60 e bitsa li-ruble tse 970, theko ea tanakan 40mg bakeng sa matlapa a 90 a 1580, ha tanakan e sa nthuse, mme likhahla tsa Bilobil li ile tsa nyoloha. Mathata a ho hopola a hloka tharollo ka mokhoa oa sethethefatsi sa boleng bo holimo, se tšepahalang. Bilobil Intensity e ile ea phekoloa mme ha ke sa na bothata ba ho hopola. Mme hlooho ha e peteke, ha e utloe bohloko. Empa ntho ea bohlokoa ke hore ka hlooho e hlakileng ho bonolo haholoanyane ho sebetsa le ho etsa lintho tsa letsatsi le letsatsi.
5. Olya. Ke ile ka noa thupelo ea likhoeli tse tharo ea bilobil intens. Ho ikutloa o le motle. Hlooho ea ka e ile ea khanya, ho bonolo ho nahana, ke hopola ntho e ngoe le e ngoe 'me ha ke ferekanye letho. Maikutlo a sa thabiseng a kang ho tsekela a felile, 'me bokhoni ba ho lemoha bo eketsehile joaloka bongoaneng. Bilobil o molemo ho feta lithethefatsi tse ngata tse nang le ginkgo, sena ke setlhare, eseng se sebe, sa tlhaho ebile se matla, ka hona ke ikutloa ke le moholo. Pele o ne a noa ginkoom, empa ha ho na litholoana. Kamora ho koenya, ke fetela bobe bohle. Mme Bilobil ke sethethefatsi. E lokela chelete ka kotloloho.

Lingaka tse ngata li fana ka bopaki ba hore ho rengoa ha sefate sa ginkgo ke sona feela setlhare se ntlafatsang ts'ebeliso ea kelello ho bakuli ba tsofetseng. Leha ho le joalo, liphuputso li boetse li bontšitse hore kamora ho khaoloa ha Bilobil ho bakuli ba sehlopha sena, ho khutla hoa matšoao a amanang le lilemo ho a bonoa.

Manonyeletso a meriana ke meriana Bilobil, Vitrum Memori, Gingium, Ginos, Memoplant le Tanakan.

Li-analogues tsa Bilobil ke lithethefatsi tse kang:

• Memantine
• Memorel,
• Noojeron
• Akatinol Memantine,
• Alzeym
• Intellan
• Memaneirin
• Memorant
• Maruks
• Memantinol
• Memikar.

Pele u sebelisa li-analogues, etela ngaka ea hau.

Maemo a polokelo le bophelo ba sehatsetsing

Setlhare sena se loketse ho sebelisoa lilemo tse tharo. Se ke oa fana ka monyetla oa ho bana, sireletsa ho tloha leseli. Mocheso oa polokelo 200C.

Sehlopha sa tliliniki le meriana

Inhibitor ea H + -K + -ATPase. Lithethefatsi tsa antiulcer

Fomu ea tokollo, sebopeho le sephutheloana

◊ Li-capsules tsa Enteric gelatin e thata, saese ea 3, e nang le 'mele o mosoeu le' mala o moputsoa, ​​litaba tse ka har'a likhapetla tsena li ngotsoe ka bophara ho tloha ho bosoeu ho isa ho bosoeu ka tisi e bolila kapa e putsoa.

* rabeprazole, pellet ntho 8,5% - 118 mg.

Baeti: libaka tsa tsoekere (sucrose - 99.83%, povidone - 0,17%) - 71.46 mg, sodium carbonate - 1,66 mg, talc - 1.77 mg, titanium diode - 0,83 mg, hypromellose - 14,75 mg.

Ba hlahisang likhetla tsa pellet: hypromellose phthalate - 15.94 mg, joala ba cetyl - 1.59 mg.
Karolo ea khalase ea lebili le thata ea gelatin 3: setopo sa capsule - titanium dioxide - 2%, gelatin - ho fihla ho 100%, capule cap - titanium dioxide - 2%, dae e putsoa e nang le patsi - 0,0176%, dae e ntšo ea daemane - 0,0051%, gelatin - ho fihla 100%.

Li-pcs tse 5. - Liphutheloana tsa blister (1, 2, 3) - lipakete tsa karete. - Liphutheloana tsa blister (1, 2, 3) - lipakete tsa karete ea likarete. 10 likhomphutha. - Liphutheloana tsa blister (1, 2, 3) - lipakete tsa karete.

14 li-PC. - Liphutheloana tsa blister (1, 2, 3) - mekotla ea likarete tse 15 likhomphutha. - Liphutheloana tsa blister (1, 2, 3) - mekotla ea likarete tse 20 likhomphutha tse 20. - Liphutheloana tsa blister (1, 2, 3) - lipakete tsa karete.

Li-pcs tse 30 - Liphutheloana tsa blister (1, 2, 3) - lipakete tsa karete.

Ketso ea pharmacological

Inhibitor ea H + -K + -ATPase. Lithethefatsi tsa antiulcer.

Rabeprazole sodium ke ea sehlopha sa likhomphutha tsa antisecretory tse tsoang benzimidazole. Rabeprazole sodium e thibela secretion ea lero la sefuba ka ho thibela H + / K + -ATPase ka lekunutu la lisele tsa parietal tsa mpa.

H + / K + -ATPase ke mochine o rarahaneng o sebetsang joaloka pompo ea proton, ka hona, rabeprazole sodium ke inhibitor ea pampiri ea proton ka mpeng mme e thibela karolo ea ho qetela ea tlhahiso ea acid.

Phello ena e itšetlehile ka tekanyetso mme e lebisa ho ho hatelloa ka bobeli ka basal le ho susumetsoa ha secretion ea acid, ho sa tsotelehe ho khopisa. Sodium ea Rabeprazole ha e na thepa ea anticholinergic.

Kamora ho tsamaisoa ha molomo oa sodium ea rabeprazole ka tekanyo ea 20 mg, ts'ebetso ea antisecretory e tsoela pele ka nako ea hora ea 1. Thibelo ea basal le e susumetsang acid secretion lihora tse 23 ka mor'a ho nka tekanyetso ea pele ea sodium ea rabeprazole ke 69% le 82%, ka ho latellana, 'me e nka lihora tse 48.

Nako ena ea ketso ea pharmacodynamic e feta hole le e boletsoeng esale pele ke T1 / 2 (hoo e ka bang hora e le 'ngoe). Phello ena e ka hlalosoa ka ho tlama ha nako e telele hoa lithethefatsi ho H + / K + -ATPase ea lisele tsa parietal tsa mpa.

Boleng ba phello ea inhibitory ea rabeprazole sodium ho secretion ea acid e fihla sehlabeng kamora matsatsi a 3 a ho nka sodium ea rabeprazole. Ha o emisa ho etsa ts'ebetso ea sekhukhu e ea khutlisoa matsatsing a 1-2.

Kameho ea ho tebeloa ha gastrin ho plasma ea mali

Litekong tsa bongaka, bakuli ba ile ba nka sodium ea rabeprazole ka tekanyetso ea 10 kapa 20 mg letsatsi le letsatsi bakeng sa nako ea kalafo e ka bang likhoeli tse 43. Keketseho ea gastrin plasma ea mali e ile ea eketseha bakeng sa libeke tse 2-8 tsa pele, tse bonts'ang phello ea inhibitory ho secretion ea acid. Ts'oaetso ea gastrin e khutletse boemong ba eona ba pele, hangata kamora libeke tse 1-2 kamora ho khaotsa kalafo.

Kameho ho lisele tse kang enterochromaffin

Ha ho hlahlojoa mehlala ea "biopsy" ea motho ka mpeng ho tsoa mokokotlong le ka tlase ho mpa, bakuli ba 500 ba amohetseng rabeprazole sodium kapa setlhare sa papiso bakeng sa libeke tse 8, liphetoho tse tsitsitseng mo sebopeho sa morphological sa lisele tse tšoanang le enterochromin, ho teba ha gastritis, khafetsa ha atrophic gastritis, metaplasia ea methapo kapa ho ata ha Helicobacter. hlokometsoe.

Phuputsong ea bakuli ba fetang 400 ba fumaneng rabeprazole sodium (10 mg / letsatsi kapa 20 mg / letsatsi) ho fihlela selemo se le seng, liketsahalo tsa hyperplasia li ne li le tlase ebile li bapisoa le seo bakeng sa omeprazole (20 mg / kg). Ha ho na linyeoe tsa liphetoho tse makatsang kapa lihlahala tsa nama ea mokokotlo tse bonoang litekong.

Liphetho tsa systemic tsa rabeprazole sodium mabapi le tsamaiso ea methapo e bohareng, tsamaiso ea methapo ea pelo kapa ea ho hema ha e sa fumanoa.

Ho ile ha bontšoa hore sodium ea rabeprazole, ha e nooa ka molomo ka tekanyetso ea 20 mg bakeng sa libeke tse 2, ha e ame ts'ebetso ea qoqotho, metabolism ea carbohydrate, khatello ea li-parathyroid hormone maling, hammoho le khatello ea cortisol, estrogen, testosterone, prolactin, glucagon, FSH, LH , renin, aldosterone le hormone ea kholo.

Mofumahali

Tlhahiso le kabo

Rabeprazole e kenella ka potlako ka popelong, Cmax e plasma ea mali e fihlella lihora tse ka bang 3.5 ka mor'a tsamaiso ka tekanyo ea 20 mg. Liphetoho ho Cmax ho plasma ea mali, litekanyetso tsa AUC tsa rabeprazole li kahare ho litekanyetso ho tloha ho 10 ho isa ho 40 mg.

Boaoavailability e felletseng ka mor'a taolo ea molomo ka tekanyo ea 20 mg (bapisoa le iv) e ka ba 52%. Ntle le moo, bioavailability ha e fetohe ka litekanyetso tse ngata tsa rabeprazole. Leha e le nako ea ho sebelisa lithethefatsi motšehare, kapa tsamaiso e tšoanang ea li-antacid ha e ame ho amoheloa ha rabeprazole.

Ho nka lithethefatsi ka lijo tse nang le mafura ho fokotsa ho kenngoa ha rabeprazole lihora tse 4 kapa ho feta, leha ho le joalo, Cmax kapa boemo ba ho fetoloa ha bo fetole.

Ho tlangoa ha rabeprazole ho liprotheine tsa plasma hoo e ka bang 97%.

Metabolism le excretion

Metabolite e ka sehloohong ke thioether (M1). Metabolite e le 'ngoe feela e sebetsang ke desmethyl (M3), leha ho le joalo, e ne e ikemiselitsoe ka khatello e tlase ho karolo ea morupeluoa a le mong feela ea thuto ka mor'a ho nka rabeprazole ka tekanyo ea 80 mg.

Kamora tekanyetso e le 'ngoe ea sodium e' ngoe ea 14C e ngotsoeng ke rabeprazole sodium ka 20 mg, ha ho na moriana o sa fetoloang mokokotlong.

Hoo e ka bang karolo ea 90% ea rabeprazole e epeloa ka liphio haholo ka sebopeho sa metabolites tse peli: conjugate ea mercapturic acid (M5) le carboxylic acid (M6), hammoho le mofuta oa li-metabolites tse peli tse sa tsejoeng tse fumanoeng nakong ea tlhahlobo ea chefo. Karolo e setseng ea sodium ea rabeprazole e nkuoeng e epolloa ka mala.

Ho felisoa ka botlalo ke 99,8%. Lintlha tsena li bonts'a excretion e nyane ea rabeprazole sodium metabolites e nang le bile.

Ho baithaopi ba phetseng hantle, plasma T1 / 2 e ka ba hora e le 'ngoe (ho fapana le lihora tse 0,7 ho isa ho tse 1,5),' me botlalo ba eona ke 3,8 ml / min / kg.

Pharmacokinetics ka lihlopha tse khethehileng tsa bakuli

Ho bakuli ba nang le tšenyo ea sebete e sa foleng, AUC e imena habeli ha e bapisoa le baithaopi ba phetseng hantle, e leng se bontšang ho fokotseha ha metabolism nakong ea "pass ea pele", mme T1 / 2 ho tsoa ho plasma ea mali e eketseha ka makhetlo a 2-3.

Ho bakuli ba nang le ho hloleha ha methapo e tiileng ea pheletsong ba hlokang ho lokisoa ha hemodialysis (CC)

• Bokaholimo bo le bong ba Bilobil bo na le 40 mg ea likhaba tse tsoang makhasi a sefate ginkgo e mebala e 'meli.
• K'hasete e le 'ngoe ea Bilobil Forte e kenyelletsa 80 mg ea monokotšoai makhapetleng a sefate ginkgo e mebala e 'meli.

100 mg ea ntsa e kenyelletsa 19.2 mg ginkgo glycosides mofuta oa flavone le 4.

8 mg terpene lactones mofuta (bilobalides le ginkgolides).

Lintho tse ling: colloidal silicon oxide, starch ea poone, lactose monohydrate, magnesium stearate, talc.

Sebopeho sa Shell: dae oxide e khubelu, titanium dioxide, azorubine, dae oxide oxide, gelatin.

Fomu ea tokollo

Li-capsules tsa pinki tsa galatin, ka hare li na le phofo e sootho e nang le likaroloana tse bonahalang tse lefifi. Li-capsules tse 10 ka blister, lilomo tse peli kapa tse tšeletseng ka har'a pakete ea karete.

Ketso ea pharmacological

Neurometabolic, antihypoxice ntlafatsang ho ikatisa, ho ntlafatsa ho potoloha le ho potoloha ha lisele, angioprotective, antioxidant ketso.

Pharmacodynamics le pharmacokinetics

Pharadodynamics

Phytopreparation, normalize metabolism ka har'a lisele rheological matšoao madi le tokafatso ea linama.

E ntlafatsa ho potoloha ha 'mele' me e fana ka kelello tsoekere le oksijenee thibela ho kopana lisele tse khubelu tsa malie hatella ts'ebetso palo ea liplatelete.

E na le litekanyetso tse laolang litekanyetso tsa methapo tsamaisong ea methapo, li kenya ts'ebetso tlhahiso TSIETSI, e ntlafatsa leseli la li-arterioles, e eketsa molumo oa methapo, ka ho etsa joalo e fetola ho tlatsoa ha methapo ea mali. E nyenyefatsa ho fokola ha lebota la sekepe.

Melemo antithrombotic ketso (e matlafatsa lera la lisele tse khubelu tsa mali le liplatelete, e ama biosynthesis li-prostaglandinse fokolisa litlamorao platelet-activating factor) E thibela peroxidation ea mafura a membrane ea lisele le ho etsoa ha li-radicals tsa mahala.

Normalizing metabolism li-neurotransmitters (joalo ka dopamine, norepinephrine le acetylcholine) Hape o na le antihypoxic ketso, e tsosa metabolism, e khothalletsa ho bokella macroergse potlakisa ho lahla tsoekere le oksijenee laola lits'ebetso tsa bobuelli bokong.

Mofumahali

Kamora ho nka bioavailability bilobalida le ginkgolides ke 85%. Ts'isinyo e phahameng ka ho fetisisa e tlalehiloe lihora tse peli kamora ho sebelisa moriana. Ho felisoa ha halofo ea bophelo ke lihora tse 4-10. Limolek'hule tsa lintho tsena ha li senyehe 'meleng' me li huleloa ka botlalo ka moroto, ho isa tekanyong e nyane - ka makhopho.

Matšoao a ho sebelisoa

• Ho potoloha ka bongata le ho potoloha ha mali, Lefu la Raynaud.

Discirculatory encephalopathy ka lebaka la stroke, ho sithabela maikutlo, lilemo le lisosa tse ling, tse tsamaeang le ho fokolisa mohopolo, tlhokomelo, ho fokotseha hoa bokhoni ba kelello, phetoho ea mekhoa ea ho robala.

Contraindication

• Lefu la ho ruruha.
• Fokotsa coagulability.
• Kotsi ea bokuli bo amanang le "cerebrovascular".
• Alsa ea Peptic mokhatlong o boima.
• Myocardial infarction.
• Sensitization ho likarolo tsa moriana.
• Lilemo ho isa ho lilemo tse 18.

Litlamorao

• Lintho tse amanang le tšebetso ea methapo: ho hloka boroko, hlooho e bohlokoho se utloe hantle litsebeng.

Litaelo tsa ho sebelisoa (Mokhoa le litekanyetso)

Lipilisi li lokela ho metsoa ka botlalo ka metsi. Pele o qala ho e kgothaletsa ho etela ngaka. Matšoao a ntlafalitsoeng a ka hlaha kamora khoeli ea 1 ea kalafo. Nako ea kalafo ha ea lokela ho ba ka tlase ho likhoeli tse tharo.

Lipapole (matlapa) Bilobil, litaelo tsa tšebeliso

Ho discirculatory encephalopathy sebelisa li-capsules tsa 1-2 makhetlo a mararo ka letsatsi.

Ka kalafo tlolo ea molaomicrocirculation le potoloho ea potoloho, Lefu la Raynaud nka sekotlolo se le seng makhetlo a mararo ka letsatsi.

Ho lefu la tsoekere, retinopathylilemo dnchafatso ea macular ho khothaletsa 1 capsule makhetlo a mararo ka letsatsi.

Litaelo tsa ho sebelisoa ha Bilobil Forte le Bilobil Intens 120

Bilobil Forte hangata e nkoa e le sekhahla se le seng habeli kapa hararo ka letsatsi, 'me Bilobil Intens 120 e nkuoa 1 nako e le ngoe (hoseng) kapa makhetlo a 2 (hoseng le mantsiboea) ka letsatsi.

Bongata

Ha ho na litlaleho tsa linyeoe tse tlalehiloeng tsa bosholu bo feteletseng.

Litlhahlobo mabapi le Bilobil

Litlhahlobo mabapi le Bilobil Fort, Bilobil le Bilobil Intens li tšoana hantle 'me haeba li sebelisoa ka nepo, li bonts'a katleho ea lithethefatsi ho ntlafatsa phallo ea likhoerekhoere.

Litlhahlobo tsa lingaka li ipapisitse le bopaki bo ke keng ba qojoa, bo fanang ka maikutlo a hore ho huloa ha sefate sa Ginkgo ke hoo e ka bang sesebelisoa se tsebahalang se ntlafatsang ts'ebeliso ea kelello ho bakuli ba tsofetseng.

Leha ho le joalo, liphuputso li boetse li bontšitse hore matšoao a amanang le lilemo a tloaetse ho khutla ka mor'a ho tlohela lithethefatsi.

Theko, ho reka

Naheng ea Russia, theko ea Bilobil No. 20 ke li-ruble tse 156-211, theko ea Bilobil Forte No 20 ke li-ruble tse 273-290, 'me theko ea Bilobil Intens No. 20 e qala ho li-ruble tse 418.

Ukraine, litheko tse tloaelehileng tsa lithethefatsi tsena ke 99, 152 le 203 hizvnias, ka ho latellana.

• Apotheke Inthaneteng Russia
• Makhemisi a marang-rang a UkraineUkraine
• Apotheken inthanete Kazakhstan

• Li-capsules tsa Bilobil 40 mg 60 likhomphutha KRKA KRKA
• Li-capsules tsa Bilobil forte 80 mg 60 likhomphutha KRKA KRKA
• Bilobil Intens li-capsules tse 120 mg mg, li-pcs tse 60 tsa KRKA KRKA
• Bilobil Intens li-capsules tse 120 mg mg, likhomphutha tse 20 tsa KRKA KRKA
• Li-capsules tsa Bilobil forte 80 mg 20 likhomphutha KRKA KRKA

• Bilobil 40mg No. 20 li-capsules KRKA-Rus
• Bilobil Forte 80mg No. 60 li-capsules KRKA-Rus
• Bilobil 40mg No. 60 li-capsules KRKA-Rus
• Bilobil Forte 80mg No. 20 li-capsules KRKA-Rus
• Bilobil Intense 120mg No. 60 li-capsules KRKA-Rus

Pharma IFC

• Bilobil Forte KRKA, Slovenia
• Bilobil Intens 120KRKA, Slovenia
• Bilobil Intens 120KRKA, Slovenia
• Bilobil Forte KRKA, Slovenia

• Bilobil forte capsules 80mg No. 20KPKA (Slovenia)
• Bilobil capsules 40mg No. 60KPKA (Slovenia)
• Bilobil forte capsules 80mg No. 60KKKA (Slovenia)

Pani Pharma

• Li-capobil. 40mg No. 20KKKA
• Li-capobil. 40mg No. 20KKKA
• Li-capobil. 40mg No. 20KKKA
• Li-capobil. 40mg No. 20KKKA

• Bilobil Intens 120 mg No. 60 likhahla.
• Bilobil forte 80 mg No. 20 li-cap.
• Bilobil Forte 80 mg No. 60 li-cap.

ETSA PAKI! Tlhahisoleseling mabapi le meriana setsing sa marang-rang ke mofuta-kakaretso Pele o sebelisa sethethefatsi Bilobil, etsa bonnete ba hore o buisana le ngaka ea hau.