Diabeteson MV

Diabeteson MV (Diabeteson MR): Litlhahlobo tse 2 tsa lingaka, litekolo tse 3 tsa bakuli, litaelo tsa tšebeliso, li-analogues, infographics, mofuta o le mong oa tokollo.

Lingaka li hlahloba ka lefu la tsoekere Mellitus MV

Ka ho bolaoa ke lefu la tsoekere, sethethefatsi sena se lekana glycemia hantle. Phallo e fetotsoeng e lumella ho thibela hypoglycemia, ka hona, lithethefatsi li loketse bakuli ba tsofetseng, hammoho le bakuli ba nang le mafu a methapo ea pelo.

Khafetsa, empa e ka baka hypoglycemia.

Ke sebelisa lithethefatsi haholo haholo ts'ebetsong ea ka. Theko e ea utloahala, ts'ebetso e ntle haholo.

Lithethefatsi "Diabeteson MV" e sebelisoa ho litekanyetso tse fapaneng tsa 30 kapa 60 mg. Tsena ke litafole tsa tokollo tse fetotsoeng. Setlhare se na le ts'ebetso e sebetsang haholo ebile e na le ts'ebetso. Ha ho na litla-morao, phello ea lithethefatsi e qala kamora nako e potlakileng. E thehiloe hantle bakeng sa kalafo ea lefu la tsoekere.

Tlhahlobo ea Mamello bakeng sa Diabeteson MV

Monna oa ka o na le tsoekere e ngata. Ka lilemo tse 'maloa, ba ne ba batla sethethefatsi se neng se tla fokotsa tsoekere,' me ka holim'a tsohle, o ne a batla a lekana le maemo. Puisanong e latelang le ngaka e eang teng, re ile ra eletsoa moriana o bitsoang "Diabeteson MV". Kamora ho qeta khoeli a sebelisa sethethefatsi, tsoekere e ile ea khutlela ho tloaelehileng. Joale monna oa hae o na le limilimithara tse 8,2. Sena, ehlile, ke boemo bo phahameng haholo. Empa e molemo ho feta limilimithara tse 13 000 tse neng li le teng pele.

Litekanyetso tse behiloeng tsa "Diabeteson" tsa 60 mg ka letsatsi, ha li fokotsehe haholo. Hoseng ho ne ho e-na le tsoekere 10-13. Eaba ngaka e eketsa litekanyetso li ea ho 90 mg (1.5 tab). Joale hoseng, ha ke lekanya tsoekere, e ne e bile e le 6. Ke tlameha ho bolela hore ho hongata ho feta ho latela hore na ke latela mokhoa o nepahetseng oa phepo. Ho tšoana hantle le 6 ho ne ho se na mathata a ho ja. Ho joalo, hammoho le ho ikoetlisa hanyane ka hanyane.

Ke e nkile selemo, phello e ntle, phello e bonahala ebile e potlakile. Litla-morao ha li etsahale. Pheko e ntle.

Thutela-litso

Moemeli oa hypoglycemic ea molomo, e fumanoang molokong oa bobeli. E hlohlelletsa secretion ea insulin ke lisele tsa β-tsa manyeme. Eketsa kutloisiso ea lisele tsa peripheral ho insulin. Kamoo ho bonahalang kateng, e matlafatsa ts'ebetso ea li-enzyme tse ka hare (haholo-holo, mesifa ea glycogen synthetase). Fokotsa nako ea ho qalella ho tloha motsotso oa ho ja ho isa ho qala ho secretion. E khutlisa tlhoro ea pele ea "insulin secretion", e fokotsa tlhoro ea "hyperglycemia" ea postprandial.

Glyclazide e fokotsa khokahano ea liplatelete le ho kopana, e liehisa nts'etsopele ea "parietal thrombus", 'me e eketsa ts'ebetso ea methapo ea methapo. Normalizing ho hlaphoheloa ha methapo ea pelo. E na le thepa ea anti-atherogenic: e theola khatello ea cholesterol e felletseng (Ch) le LDL-C maling, e eketsa bongata ba HDL-C hape e fokotsa lenane la li-radicals tsa mahala. E thibela nts'etsopele ea micothrombosis le atherosclerosis. E ntlafatsa microcirculation. E fokotsa kutloisiso ea methapo ho adrenaline.

Ka lefu la tsoekere le lefu la tsoekere le tšebeliso ea nako e telele ea gliclazide, ho bonahala phokotseho e kholo ea proteinuria.

Mofumahali

Kamora ho tsamaisoa ka molomo, e kenella ka potlako ho tsoa mokokotlong oa lijo. C_max maling a fihlelloa lihora tse ka bang 4 ka mor'a ho nka tekanyetso e le 'ngoe ea 80 mg.

Plasma protein e tlamang ke 94.2%. V_d - boholo ba 25 l (0,35 l / kg boima ba mmele).

E tšelisoa ka har'a sebete ho hlaha metsoako e robeli ea metsoako. Metabolite ea mantlha ha e na phello ea hypoglycemic, empa e na le phello ho microcirculation.

T_1/2 - Lihora tse 12. E pepesitsoe haholo ke liphio ka mokhoa oa metabolites, e ka tlase ho 1% e pepesitsoeng ka har'a moroto o sa fetoheng.

Fomu ea tokollo

Matlapa a lokolotsoeng a tšoeu a tšoeu, a teng, a ngotsoe ka mahlakoreng ka bobeli: ka ho le leng ke logo ea k'hamphani, ka lehlakoreng le leng - "DIA30".

Ba fanang ka thuso: calcium hydrogen phosphate dihydrate, maltodextrin, hypromellose, magnesium stearate, anhydrous colloidal silicon dioxide.

Li-pcs tse 30 - Mabokose (1) - liphutheloana tsa karete.
Li-pcs tse 30 - Mabokose (2) - lipakete tsa karete.

Tšebelisano

Phello ea hypoglycemic ea gliclazide e na le tšebeliso ea ts'ebeliso e le 'ngoe ka lintho tse tsoang ho pyrazolone, salicylates, phenylbutazone, lithethefatsi tsa antibacterial sulfonamide, theophylline, caffeine, MAO inhibitors.

Ho sebelisoa ka nako e le 'ngoe ha ba khethang beta-blockers ho eketsa monyetla oa ho ntšetsa pele hypoglycemia, hape ho ka koala masesaane le ho tsitsinyeha hoa letsoho, tšobotsi ea hypoglycemia, leha ho rohakana ho ka eketseha.

Ka tšebeliso e tšoanang ea gliclazide le acarbose, ho na le phello e matla ea hypoglycemic.

Cimetidine e eketsa bongata ba gliclazide ho plasma, e ka bakang hypoglycemia (khatello ea maikutlo ea CNS, letsoalo le sa sebetseng).

Ka tšebeliso e tšoanang le GCS (ho kenyelletsa le mefuta ea litekanyetso bakeng sa ts'ebeliso ea kantle), diuretics, barbiturates, estrogens, progestin, lithethefatsi tse kopaneng tsa estrogen-progestogen, diphenin, rifampicin, phello ea hypoglycemic ea glyclazide e fokotsehile.

Litlamorao

Ho tsoa ts'ebetsong ea tšilo ea lijo: ka seoelo - anorexia, ho nyekeloa, ho hlatsa, lets'ollo, bohloko ba epigastric.

Ho tsoa ho sistimi ea hemopoietic: maemong a mang - thrombocytopenia, agranulocytosis kapa leukopenia, anemia (hangata e fetoha).

Ho tsoa tsamaisong ea endocrine: e nang le overdose - hypoglycemia.

Boitšoaro bo kulisang: lekhopho la letlalo, ho hlohlona.

Type 2 lefu la tsoekere la mellitus le sa sebetsang hantle kalafo ea ho ja, ho ikoetlisa le ho theola boima ba 'mele.

Thibelo ea mathata a mofuta oa lefu la tsoekere la mofuta oa 2: ho fokotsa kotsi ea microvascular (nephropathy, retinopathy) le mathata a macrovascular (infarction ea myocardial, stroke).

Litaelo tse khethehileng

Gliclazide e sebelisetsoa ho alafa mellitus e sa itšetleheng ka insulin hammoho le lijo tse nang le khalori e tlase e tlaase.

Nakong ea kalafo, o lokela ho lekola khafetsa boemo ba tsoekere maling maling ka mpeng e se nang letho le ka mor'a ho ja, ho fetoha ha maemo a letsatsi le letsatsi ka bongata.

Maemong a ts'ebetso ea ts'ebetso ea bongaka kapa ho bola ha lefu la tsoekere, ho hlokahala hore u nahane ka monyetla oa ho sebelisa litokisetso tsa insulin.

Ka nts'etsopele ea hypoglycemia, haeba mokuli a le teng, ho na le glucose (kapa tharollo ea tsoekere) kahare. Bakeng sa tahlehelo ea kelello, glucose e kenang kapa glucagon sc, intramuscularly kapa intravenous e tsamaisoa. Kamora ho hlaphoheloa kelellong, ho bohlokoa ho fa mokuli lijo tse nang le lik'habohaedreite e le ho qoba tsoelopele ea hypoglycemia.

Ka ts'ebeliso e ts'oanang ea gliclazide e nang le verapamil, ho hlokahala hore ho hlahlojoe litekanyetso tsa tsoekere ea mali kamehla, ka acarbose, ho lekola ka hloko le ho khalemela litekanyetso tsa litekanyetso tsa li-hypoglycemic agents.

Tšebeliso e tšoanang ea gliclazide le cimetidine ha e khothalletsoe.