Setlolo sa mahlo sa Ofloxacin

ka marang-rang kapa ka sekotlolong sa likhomphutha tse 10., ka paketeng ea karete e le 1 kapa pakete.

ka botlolong ea khalase e lefifi ea 100 ml, ka har'a pakete ea karete e le 1.

ka methapo ea aluminium ea 3 kapa 5 g, ka paketeng ea karete e le ngoe ea 1.

Pharadodynamics

E sebetsa khahlanong le likokoana-hloko tse hlahisang beta-lactamase le mycobacteria e atang ka potlako. Sensitive: Staphylococcus aureus, Staphylococcus epidermidis, Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Citrobacter, Klebsiella spp., (Ho kenyelletsa Klebsiella pneumoniae), Enterobacter spp. (ho kenyeletsoa Enterobacter cloacae), Hafnia, Proteus spp. (ho kenyeletsoa Proteus mirabilis, Proteus vulgaris - indole e ntle le indole mpe), Salmonella spp., Shigella spp. (ho kenyelletsa Shigella sonnei), Yersinia enterocolitica, Campylobacter jejuni, Aeromonas hydrophila, Plesiomonas aeruginosa, Vibrio cholerae, Vibrio parahaemolyticus, Haemophilus influenzae, Chlamydia spp. (ho kenyeletsoa Chlamydia trachomatis), Legionella spp., Serratia spp. Providencia spp., Haemophilus ducreyi, Bordetella parapertussis, Bordetella pertussis, Moraxella catarrhalis, Propionibacterium acnes, Staphylococcus spp, Brucella.

Fapaneng nahanela ho ea lithethefatsi e rua: Enterococcus faecalis, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus viridans, Serratia marcescens, Pseudomonas aeruginosa, Acinetobacter, Mycoplasma hominis, Mycoplasma pneumoniae, Mycobacterium lefuba, Mycobacterium fortuitum, Ureaplasma urealyticum, Clostridium perfringens, Corynebacterium spp, Helicobacter pylori. , Listeria monocytogene, Gardnerella vaginalis.

Maemong a mangata, e sa tsotelleng: Nocardia asteroides, libaktheria tsa anaerobic (e.g. Bacteroides spp., Peptococcus spp., Peptostreptococcus spp., Eubacterium spp., Fusobacterium spp., Clostridium Hardile). Ha e sebetse bakeng sa Treponema pallidum.

Mofumahali

Kamora ho tsamaisoa ka molomo, e kenella ka potlako le ka botlalo. Bioavailability - ho feta 96%, e tlamang ho protheine ea plasma - 25%. T_max ke lihora tse 1-2, C_max kamora ho nka tekanyetso ea 100, 300, 600 mg ke 1, 3.4 le 6.9 mg / L. Kamora tekanyetso e le 'ngoe ea 200 kapa 400 mg, ke 2,5 μg / ml le 5 μg / ml, ka ho latellana.

Bophahamo bo bonahalang ba thomello ke lilitha tse 100. E kenella ka har'a lisele, litho tsa 'mele le mecha ea phatlalatso ea' mele: liseleng (lisele tse tšoeu tsa mali, li-macrophages tsa alveolar), letlalo, lisele tse bonolo, masapo, litho tsa ka mpeng le tsa pelvic, sistimi ea ho hema, urine, lesere, bile, secretion ea prostate, e feta hantle ka BBB, sethopo sa placental, se kentsoeng lebese la matsoele. E kenella ka har'a mokelikeli oa "cerebrospinal" o nang le lipompo tsa banna le litlamorao tse sa tlisoang (14-60%).

E etselitsoe sebete "(hoo e ka bang 5%) ka sebopeho sa N-oxide ofloxacin le dimethylofloxacin. T_1/2 ha e ea itšetleha ka lethal dose mme ke lihora tse 4,5-7. E supiloe ke liphio 75-90% (e sa fetoheng), e ka bang 4% - ka bile. Tlhahiso e eketsehileng - e ka tlase ho 20%.

Kamora tekanyetso e le 'ngoe ea 200 mg ka moroto, e fumanoa ka nako ea lihora tse 20-24. Ka ho haella ha renal / hepatic, excretion e ka theoha butle. Ha e balehe.

Matšoao Ofloxacin

Ts'oaetso ea mokhoa oa ho hema (bronchitis, pneumonia), litho tsa ENT (sinusitis, pharyngitis, otitis media, laryngitis), letlalo, mesifa e bonolo, masapo, manonyeletso, mafu a tšoaetsanoang le a tšoaetsanoang a litho tsa ka mpeng le lesapo la mokokotlo (ntle le tšoaetso ea baktheria), liphio ( pyelonephritis), pampiri ea urine (cystitis, urethritis), litho tsa kahare le matsoele (endometritis, salpingitis, oophoritis, cervicitis, parametritis, prostatitis, colpitis, orchitis, epididymitis), gonorrhea, chlamydia, septicemia (bakeng sa Tsamaiso ea IV feela) , meningitis, thibelo ea tšoaetso ho ol by le boemo litsebeng boitshireletso (ho akarelletsa le neutropenia le), baktheria corneal liso, conjunctivitis, blepharitis, meybomit (harese), dacryocystitis, keratitis, tšoaetso chlamydial ea leihlo.

Sebopeho le thepa

Setlolo sa mafura sa Ofloxacin ke setlhare se tsoang sehlopheng sa fluoroquinolones se nang le thepa ea antibacterial.

E fumaneha ka methapo ea aluminium ea 3 kapa 5 g. Sephutheloana sena se na le litaelo tsa hore se sebelisoe. Motsoako o sebetsang ke oaloloacacin. Lintho tse ling:

• methyl parahydroxybenzoate,
• petroleum jelly,
• propyl parahydroxybenzoate.

Ha o sebelisa sethethefatsi, motsoako o sebetsang oa lithethefatsi o na le phello ho "gilli" ea "bacilli enzyme" e netefatsang botsitso ba DNA ea likokoana-hloko tse kotsi. Ka lebaka leo, libaktheria li qala ho shoa. Ofloxacin e sebetsa haholo kamanong le mefuta e latelang ea bacilli:

Karolo e ka sehloohong ea lithethefatsi e senya salmonella.

• staphylococci,
• Esherichia coli,
• Providencia spp.,
• shigella
• Haemophilus influenzae,
• Salmonella
• Neisseria meningitidis,
• chlamydia
• ketsona
• Propionibacterium acnes,
• Pseudomonas aeruginosa,
• Morganella morganii,
• Pseudomonas aeruginosa,
• brucella
• Klebsiella,
• Mycoplasma et al.

Ka tsamaiso ea kantle, karolo e sebetsang e bonoa ka setsing sa conjunctiva, iris, cornea, sclera, mesifa le kamoreng ea ka ntle. Ka tšebeliso e sa khaotseng, ho kenella ha ntho ea mantlha ho vitreous hoa phethahala. Liseleng, ho sebelisoa sehlooho se phahameng sa moriana ho feta mongobo oa mahlo. Phekolo e phahameng ea lithethefatsi ka har'a methapo ea sclera le conjunctiva e etsoa ka nako ea metsotso e 5. kamora ho beha moriana, mme litho tse sebetsang li oela mokhoeng oa metsi kamora hora e le 'ngoe. Ebe mahlahana a lithethefatsi a fokotseha butle.

Mafura a Ofloxacin a laeloa bakeng sa maloetse a latelang a pono:

• Maloetse a baktheria mahlo - blepharitis, keratitis, conjunctivitis, jj.
• lits'ebetso tsa chlamydial tsa ts'oaetso ea litho tsa bonono,
• dacryocystitis
• corneal ulceration,
• harese
• thibelo ea mathata ka mor'a ho etsoa opereishene ea mahlo.

Litaelo tsa ho sebelisoa

Pele o kena moriana o hloka keletso ea ngaka ea ngaka. Bakeng sa ts'oaetso eohle ea mahlo, ntle le ts'oaetso ea chlamydial, mori o lokela ho beoa sebakeng sa karolo e ka tlase ea conjunctival ka thipa ea 1 cm ho fihlela makhetlo a 3 ka letsatsi, ka likotsi tsa chlamydial - mekhoa ea 5-6 ka letsatsi. Setlhare se fanoa ka kotloloho ho tsoa mothong. Nako ea kalafo e fihlile ho libeke tse peli. Ka mafu a chlamydial a litho tsa pono, nako ea kalafo ke matsatsi a 28-35.

Setlhare se tlameha ho kenngoa kamora ho tsamaisa lera la ka tlase.

Morero oa ho sebelisa litlolo:

1. Tsamaisa Eyelid e tlase.
2. Kenyelletsa meriana ea 10 mm sebakeng sa "conjunctival sac".
3. Koala leihlo 'me u le tsamaise ka mekhoa e fapaneng e le hore moriana o ka tsamaisoa ka nepo.

Contraindication

Setlhare sa Ofloxacin ha se sebelisoe maemong a latelang:

• hypersensitivity ho likarolo tsa moriana,
• concjunctivitis e sa foleng ea tlhaho e sa bakang baktheria,
• ho ima le ho nyekeloa
• lilemo ho fihlela lilemo tse 15.

Litlamorao

Ha u sebelisa Ofloxacin, maikutlo a joalo a nakoana e khuts'oane a ka hlaha e le:

Ka linako tse ling ka mor'a moriana o joalo, conjunctiva e ka fetoloa ka nakoana.

• tsietsi
• hyperemia,
• lacrimation
• ho hlohlona
• maikutlo a tukang
• edjunctival edema,
• leihlo le omeletseng
• Photophobia
• lipontšo tsa karabelo ea ho kulisa.

Ho lumellana

Ts'ebeliso hammoho le li-NSAIDs, nitroimidazole le methylxanthine li eketsa menyetla ea litla-morao tsa neurotoxic le litlamorao tse kholisang.

Ha o sebelisa meriana ena hammoho le meriana e meng, likarolo tse latelang li lokela ho tsotelloa:

• Tšebeliso e le 'ngoe le meriana e kenyelletsang magnesium, tšepe, aluminium kapa zinki, e thusa ho liehisa ho kenngoa ha ofloxacin. Sena se sebetsa le ho li-antacids le sucralfate.
• Ha o sebelisoa ka mokhoa o ts'oanang le li-anticoagulants tse nang le litlamorao tse sa tobang, ts'ebetso ea tsona ea eketseha, kahoo o hloka ho laola mokhoa oa ho kopanya.
• Setlhare ha se sebelisane le litlhare tse ling tsa lehae tsa mahlo. Leha ho le joalo, ka tšebeliso e tšoanang, karohano lipakeng tsa ts'ebeliso ea meriana e fapaneng bonyane metsotso e 15 ea hlokahala. Ofloxacin, ntlheng ena, e tlameha ho beoa qetellong.

Bongata

Ho latela polelo ea phatlalatso, ha ho na tlhahisoleseling mabapi le litekanyetso tse feteletseng. Haeba u ka kenella ka phoso ka moriana oa meriana, ho ka hlaha likarabelo tse latelang:

• ferekanya letsoalo
• ho tsekela
• ho otsela ho eketsehileng
• ho hlatsa
• pherekano,
• lethargy.

Maemong a joalo, o hloka:

Menahano ea lithethefatsi

Ofloxacin e na le li-substitute tse sebetsang joalo ka Azitsin, Phloxal, Vero-Ofloxacin, Tetracycline, Oflomelid, Vilprafen, Zitroks, Levomycetin. Li-analogu tsena kaofela li na le phello ea antibacterial mme li kenya letsoho ho feliseng tšoaetso ea mahlo. Pele u nkela "Ofloxacin" meriana leha e le efe, u hloka ho buisana le setsebi sa mahlo. Ngaka e tla u thusa ho khetha analogue e nepahetseng.

Matšoao a ho sebelisoa

Ho fanoa ka thepa ea antibacterial ea sethethefatsi sena, e laeloa bakeng sa kalafo ea mafu a liphio, pampitšana ea ho ntša metsi, tšoaetso ea letlalo. Ka gynecology e laetsoeng chlamydia, gonorrhea. Ka hona, meriana ena e ratoa haholo.

Ho ophthalmology, ho laetsoe boteng ba methapo le mafu a joalo:

• chlamydia leihlo
• liso tse bohloko tsa cornea,
• blepharitis
• harese
• tšenyo ea baktheria
• keratitis
• bacterium conjunctivitis.

E ka sebelisoa ho thibela mathata nakong ea ts'ebetso ea postoperative. Haholo-holo ka tšenyo ea mokokotlo.

Lingaka li khothalletsa meriana ena maemong a mangata. Ho sebetsa ha eona le litšenyehelo tse tlase li etsa hore Ofloxacin e fumanehe ho mokuli e mong le e mong. Lifekthering tsa Russia, litšenyehelo tse tloaelehileng tsa mafura ke li-ruble tse 35-65.

Ntho e sebetsang ea mafura ana ke ofloxacin. Hlahisa lithethefatsi ka likhakanyo tse fapaneng - 3 le 5 mg.

Pele o sebelisoa, o lokela ho ithuta ka hloko sebopeho sa moriana mme o khetholle boteng ba hypersensitivity kapa ho se mamellane ha motho ka mong.

Litaelo tse khethehileng

Ho bohlokoa ho ela hloko hore ka kotloloho ha e khothaletsoe ho sebelisa moriana ka joala ka nako e le ngoe. Puisano e joalo e ka lebisa ho hola hoa maikutlo a bohloko. Ketso ea moriana ha e ea fokotsoa maemong a joalo. Nakong ea kalafo, lilense tsa ho ikopanya li tlameha ho tlosoa. Haeba ho hlokahala, li nkeloa sebaka ke likhalase.

Ka linako tse ling nakong ea phekolo, bakuli ba na le kutloisiso e eketsehileng ea khanya. Ka nako e ts'oanang, ho tlosa lithethefatsi ha ho hlokahale. Mokuli o eletsoa hore a sebelise likhalase ho fihlela qetellong ea kalafo ea lithethefatsi.

Hoo e ka bang bakuli bohle, kamora ho beha setlolo, ho fokotseha hoa fokola hoa pono. Phello ena ke ea nakoana 'me e feta nakong ea metsotso e 15. Fuoa tlhahisoleseling ena, kamora mokhoa o lokela ho hana ho khanna likoloi. O ka khutlela mosebetsing le ho khanna ha pono e hlaphohetsoe.

Ho sebelisana le meriana e meng

Nakong ea ts'ebeliso ea Oflaxacin, phello ea eona e fokotseha ha e ntse e sebelisoa le lithethefatsi tse nang le tšepe, magnesium, zinki le aluminium. Phokotso ea phello e boetse e bonoa ha e kopana le li-antacid le sucralfate.

Setlolo se ka eketsa katleho ea li-anticoagulants. Ka tšebelisano ena, ho hlokahala ho laola mekhoa ea ho fetoha ha mali. Ts'ebetso ea mokelikeli le litlamorao tsa neurotoxic li ka eketseha ha li sebelisana le methylxanthine le nitroimidazoles. Litlamorao tse joalo li ka hlaha ha ho sebelisoa lithethefatsi tse seng khahlanong le ts'oaetso tsa mali.

Ho sebelisana 'moho le litokisetso tse ling tsa lehae tsa mahlo ha ho bonoe. Ka tšebeliso e tšoanang ea lithethefatsi tse fapaneng, nako ea metsotso e 15 e lokela ho bonoa. Setlolo sena se tšeloa kamora ho tšela marotholi.

Litlamorao

Setlhare sena se sireletsehile ebile ha se hangata se etsang hore re utloe bohloko. Ha e le hantle, li hlaha ka mokhoa oa lipontšo tse joalo:

• ho tuka
• ho hlohlona
• kutloisiso ea khanya
• ho ruruha
• redness
• lacrimation e matla kapa karabelo e khutlisetsang morao ka sebopeho sa lefu la mahlo le omeletseng.

Mabakeng a karabelo e mpe, ho hlokahala hore o emise kalafo mme o bone ngaka ea hau. Ho felisa litlamorao tse sa batleheng, ho lekane ho hlakola meriana.

Qeto

Setlhare sa Ofloxacin ke sethethefatsi bakeng sa kalafo ea mafu a mahlo a ruruhileng a bakoang ke baktheria le likokoana-hloko tse ling tsa pathogenic. Kameho ea lehae ea lithethefatsi e u lumella ho fana ka phello e matla ka ho fetisisa ea ho phekola mohopolo oa ts'oaetso le ho khutlisetsa lisele tse amehang tsa letlalo le membrane ea mucous.

Mokhoa oa ts'ebeliso le litaelo tsa litlolo tsa Ofloxacin:

1. Hlatsoa matsoho hantle pele u a sebelisa.
2. Sula lera le ka tlase 'me u pepese lithethefatsi ho tloha ka mothapo ho mokokotlo oa conjunctival.
3. Bakeng sa tšebeliso e le 'ngoe, sebelisa moqomo oa mafura 1 cm.
4. Koala eyelid 'me u tsamaise leihlo la hau ka litsela tse fapaneng ho monya oli hantle.
5. Nako ea kalafo le setlolo sa Ofloxacin ke libeke tse peli. Mafu a mang a hloka ho eketsoa ha thupelo.

Setlolo sa Ofloxacin, litaelo tsa tšebeliso

Bakeng sa eyelid e ka tlase, 1-1,5 cm ea mafura e tšeloa makhetlo a 3 ka letsatsi. Ho ya ka ho fumaneha chlamydial eye diso - makhetlo a 5 ka letsatsi. Phekolo e etsoa ha e sa feteng libeke tse peli. Ka tšebeliso e tšoanang ea lithethefatsi tse 'maloa, mafura a sebelisoa qetellong.

Matlapa a nooa ka molomo, a felletse, pele ho lijo kapa nakong ea lijo. Tekanyetso e khethoa ho latela botebo ba ts'oaetso, sebete le ts'ebetso ea liphio. Tekanyetso e tloaelehileng ke 200-600 mg ka letsatsi, e arotsoe ka litekanyetso tse peli. Ho ts'oaetso e matla le ho nona haholo, tekanyetso ea letsatsi le letsatsi e nyolohela ho 800 mg. Ho gonorrhea 400 mg e beoa tekanyetso e le 'ngoe, hang, hoseng.

Bana ba khethoa ka mabaka a bophelo, haeba ho se na ntho e 'ngoe ka mekhoa e meng. Sekhahla sa letsatsi le letsatsi ke 7.5 mg ka kilo ea boima ba 'mele.

Bakuli ba nang le ts'oaetso ea renal e holofalitsoeng baa lumelloa. Bakeng sa bakuli ba nang le ts'ebetso e matla ea sebete 'meleng, tekanyetso ea letsatsi le letsatsi ha ea lokela ho ba ho feta 400 mg. Nako ea kalafo e khethoa ke botebo ba lefu lena. Phekolo e ntse e tsoela pele matsatsi a mang a 3 kamora ho tloaela ho fetoha ha mocheso kapa kamora liteko tsa liteko tsa laboratori Phokotso ea microorganism. Hangata, nako ea kalafo ke matsatsi a 7- 7, salmonellosis Matsatsi a 7 bakeng sa tšoaetso ea pampitšana ea urine ho fihlela matsatsi a 5. Phekolo ha ea lokela ho feta likhoeli tse peli. Ha kalafo ea mafu a itseng, Ofloxacin e fuoa pele makhetlo a mabeli ka letsatsi ka phetoho ho tsamaiso ea molomo.

Meroalo e nang le ntho e sebetsang tsaloxacin e fanoe tlasa lebitso Danzil, Phloxal, Uniflox. Bona litaelo tsa tšebeliso ea lithethefatsi tsena.

E Bontšitsoe ho tsekela, ho khutla, ho otsela, pherekano, pherekano, spasms, ho hlatsa. Phekolo e entsoe ka lavage ea gastric, diuresis e qobelloang le kalafo ea matšoao. Ka tšebeliso ea methapo ea kutlo Diazepam.

Kamora nako ya kopano sucralfatali-antacid le litokisetso tse nang le aluminium, zinki, magnesium kapa tšepe, ho monya monyaolo tsaloxacin. Ho na le keketseho ea katleho ea li-anticoagulants tse sa tobang ha li nooa le moriana ona. Tsamaiso ea sistimi ea coagulation ea hlokahala.

Kotsi ea litlamorao tsa neurotoxic le ts'ebetso e tsitsitseng e eketseha ka tsamaiso e ts'oanang ea NSAIDs, derivatives nitroimidazole le methylxanthine.

Ha e sebelisoa le Theophylline clearance ea eona ea fokotseha mme pheletso ea halofo ea bophelo e eketsehe.

Tšebeliso e tšoanang ea li-agents tsa hypoglycemic e ka lebisa maemong a hypo- kapa hyperglycemic.

Ha e sebelisoa le Cyclosporine ho na le keketseho ea khatello ea eona maling le halofo ea bophelo.

Propenecid, Furosemide, Cimetidine le Methotrexate fokotsa secretion ea tubular ea ntho e sebetsang, e kenyang keketseho ea khatello ea eona maling a mali.

Mohlomong ho fokotseha ho hoholo ha khatello ea mali ha ho sebelisoa barbiturates le antihypertensive lithethefatsi.

Ha e sebelisoa le glucocorticosteroids ho na le kotsi ea ho phatloha ha tendon.

Ho eketsa nako ea nako ea QT le ts'ebeliso ea li-antipsychotic, lithethefatsi tse felisang kalafo, lithibela-mafu tsa lithethefatsi, li-macrolides, li-derivatives tsa imidazole, astemizole, terfenadine, ebastina.

Ts'ebeliso ea li-inhibitors tsa carbonic anhydrase, sodium bicarbonate le citrate, tse arolang moroto, li eketsa kotsi ea ho ba le "crystalluria" le "nephrotoxicity".

E fanoa ka taelo ea ngaka.

Mocheso oa polokelo ho fihlela ho 25 ° C.

Joala ha bo tsamaisane le moriana ona. Nakong ea kalafo, joala ha boa lumelloa.

Matlapa: Zanocin, Zoflox, Ofloxin.

Litharollo tsa infusion: Ho joalo, Tarivid, Ofloxabol.

Anloxacin analog, e fumanehang joalo ka setlolo sa mahlo - Phloxalka mokhoa oa marotholi a mahlo / tsebe - Danzil, Uniflox.

Fluoroquinolones lula maemong a etellang pele har'a li-antimicrobial agents mme li nkuoa e le mokhoa o mong oa lithibela-mafu tse sebetsang haholo kalafo ea ts'oaetso e matla. Hajoale, moemeli ea matla oa meloko ea moloko oa bobeli ha a e-so lahleheloe ke boemo ba hae ba pele -tsaloxacin.

Monyetla oa lithethefatsi tsena holim'a fluoroquinolones tse ling ke bioavailability ea eona e phahameng haholo, hammoho le ho hanyetsa butle ha likokoana-hloko ho eona.

Ka lebaka la ts'ebetso e phahameng khahlano le likokoana-hloko tsa STI, setlhare sena se sebelisoa haholo ho dermatovenerology kalafong ea mafu a likobo: urogenital chlamydia, gonorrhea, gonorrhea-chlamydial, mycoplasma le ts'oaetso ea ureaplasma. Phokotso ea Chlamydia e bonoa maemong a 81-100% mme e nkuoa e le eona e sebetsang ka ho fetisisa ho fluoroquinolones tsohle. Sena se boetse se pakoa ke litlhahlobo tsa Ofloxacin:

• "Ke ile ka sebelisa lithethefatsi tsena, ka phekola mycoplasma le ureaplasma. Ka katleho, "
• "E nthusitse, ke noele ka cystitis, ha ho na litla-morao. Setlhare sena ha se theko e tlase ebile sea sebetsa. "

Ketsahalo e pharaletseng ea ts'ebetso, ho kenella hantle lipakeng tsa liphatsa tsa lefutso, tsamaiso ea mokokotlo, secretion ea tšoelesa ea senya, ho boloka nako e telele moqoqong ho lekola ts'ebeliso ea eona ho mafu a urological le gynecological. Kahoo, ho na le litlhahlobo tsa hore ho nka moriana ona ka matsatsi a 3 ho bontšitse katleho e kholo ho khutlisetsang cystitis ho basali. E ne e laetsoe merero ea prophylactic kamora hore diathermocoagulation ea khoholeho ea sefuba e sebetse ka mora tsamaiso lithibela-pelehi tsa intrauterinekamora ho ntša mpae sebelisitsoe ka katleho ha prostatitis, lefuba.

Kaha ha e lithibela-mafu, ha e ame limela le botšehali le mpa dysbiosis. Ho latela bakuli, pheko ena ha e mamelloe hantle. Hangata, litla-morao tse tsoang ka mpeng li ile tsa bonoa, hangata - ho tloha ho tsamaiso ea methapo e bohareng le karabelo ea letlalo, hangata seoelo - liphetoho tsa nakoana litekong tsa liteko tsa sebete. Setlhare ha se na litlamorao tsa hepato-, nephro- le ototoxic.

• "... ho ne ho nyekeloa pelo, ka mpeng e ne e le mahlooa, ho se na takatso ea lijo,"
• "... Ke ne ke kula haholo, ke sa khone ho ja letho, empa ke qetile kalafo,"
• "... Kamora ho hlobaela. Ke belaela hore ho tsoa ho sethethefatsi sena, hobane ke ne ke robala hantle, "
• "... a lahlela mollong le mofufutso o batang, ho bile le ts'abo."

Ho bakuli ba bangata ba nang le conjunctivitis, blepharitis le keratitis leihlo le behiloeng le oela le ntho e sebetsang tsaloxacin (Uniflox, Phloxal, Danzil)) Litlhahlobo tse ntle. Bakuli ba li sebelisa makhetlo a 4-5 ka letsatsi le blepharitis le conjunctivitis mme a hlokomela ntlafatso e kholo matsatsing a 2-3. Ka lebaka la ts'ebetso e phahameng ea bioavailability ea ntho e sebetsang, marotholi a ka sebelisoa le bakeng sa liso tse tebileng - uveitis, scleritis le iridocyclitis.

U ka reka sethethefatsi sena khemising efe kapa efe ea meriana. Litsenyehelo li latela moetsi. Theko ea Ofloxacin matlapeng a 200 mg ea tlhahiso ea Russia (Ozone, Makiz Pharma, OJSC Synthesis) e tsoa li-ruble tse 26. ho fihlela ho 30 rub. bakeng sa matlapa a 10, mme litšenyehelo tsa matlapa ke 400 mg No. 10 ho tloha ho li-ruble tse 53 ho isa ho tse 59. Ofloxacin Teva, e hlahisitsoeng feela ka matlapa a 200 mg, e bitsa chelete e ngata - li-ruble tse 163-180. Setlolo sa mahlo (Kurgan Synthesis OJSC) se theko ho tloha ho li-ruble tse 38 ho isa ho tse 64. litlhare tse fapaneng tsa meriana.

Theko ea Ofloxacin ho la Ukraine ke 11-14 UAH. (matlapa), 35-40 UAH. (tharollo ea infusion).

Tharollo ea Ofloxacin 2 mg / ml 100 ml ka tharollo ea sodium chloride 0,9% Synthesis ea OJSC

Levofloxacin matlapa a 500 mg 5 likhomphutha Vertex

Licrofloxacin matlapa a 250 mg li-pcs tse 10. Ozone LLC

Letlapa la Levofloxacin 500 mg 10 likhomphutha Vertex

Matlapa a Ofloxacin-Teva 200 mg 10 likhomphutha tsa Teva

Tharollo ea Levofloxacin 5mg / ml bakeng sa infusion 100ml No. 1 botlolo ea Kraspharma OJSC

Tharollo ea Ofloxacin 2mg / ml bakeng sa infusion 100ml vial Synthesis OJSC

Matlapa a Levofloxacin 500mg No. 10

Matlapa a Levofloxacin 500mg No. 5

Levofloxacin-Teva 500mg No. matlapa a 14 a Teva Pharmaceutical

Tlatsetso ea Ciprofloxacin PFK CJSC, Russia

Levofloxacin Vertex CJSC, Russia

Levofloxacin Vertex CJSC, Russia

Levofloxacin Vertex CJSC, Russia

Levofloxacin o kopantseng matlapa a 500mg No. 10 Health (Ukraine, Kharkov)

Levofloxacin matlapa a koahetsoeng a 250mg No. 10 Health (Ukraine, Kharkov)

OfloxacinKievmedpreparat (Ukraine, Kiev)

Ofloxacin Darnitsa (Ukraine, Kiev)

Tharollo ea Ofloxacin inf. 0.2% 100mlLekhim-Kharkiv

Tharollo ea Ofloxacin inf. 0.2% 100mlLekhim-Kharkiv

Tharollo ea Ofloxacin inf. 0.2% 100mlLekhim-Kharkiv

Tharollo ea Ofloxacin inf. 0.2% 100mlLekhim-Kharkiv

Tharollo ea infrodloxacin infusion tharollo ea 0,5% 100mlNovofarm-Biosynthesis

Ciprofloxacin 0,25 g No. 10 tab.po.synthesis of OJSC (Russia)

Ofloxacin setlolo sa mafura sa 0,3% 5 g. Synthesis OJSC (Russia)

Ciprofloxacin 0.5 g No. 10 tab.po.synthesis of OJSC (Russia)

Ciprofloxacin 200 mg 100 ml tharollo ea d / in. Fektheri ea meriana ea Kelun (China)

Ofloxacin 2 mg / ml 100 ml tharollo ea d / inf.Synthesis OJSC (Russia)

Setlhare sa Ofloxacin se etselitsoe ho loantša tšoaetso ea mahlo.

Setlhare sa Ofloxacin ke moemeli ea thibelang likokoana-hloko.

Sesebelisoa se ka fumanoa hoo e batlang e le meriana leha e le efe ea meriana, se ipehetse se sebetsa, ka hona, hangata se fanoa ke lingaka tsa mahlo nakong ea kalafo ea mafu a fapaneng.

Setlolo sena sa antibacterial se nang le ts'ebetso e leketlileng ntoeng ea ho loants'a libaktheria tse kang:

• Salmonella
• Serratia.
• Shigella.
• Chlamydia
• Staphylococci.
• Brucella
• Helicobacter.
• Pilori.
• Pseudomonas aeruginosa.

Setlolo sena se entsoe ka mokhoa oa ho loants'oa le litšoaetso tsa ts'oaetso le ts'oaetso sebakeng sa leihlo. Kenya litlolo ka:

1. Harese.
2. Conjunctivitis.
3. Tšoaetso ea Chlamydial ea mahlo.
4. Blepharitis.
5. Pathology ea eyelids.
6. Pathology ea cornea.

Setlolo sena se sebelisoa e le prophylactic, moo ho nang le tšoaetso ea mafu, mathata a ka mor'a ho buuoa, kamora ho ntšoa ha 'mele o tsoang ka ntle mahlong kapa ho senya sekoaelo sa mahlo.

Setlhare se etselitsoe kalafo ea tšoaetso ea mahlo, ka mokhoa oa setlolo.

• Seketsoana se seng ke methylparaben.
• Propylparaben.
• Vaseline.
• Ofloxacin.

Setlolo sena se hlahisoa ka liphutheloana tsa aluminium tse ligrame tse tharo le tse hlano. Chuburu e 'ngoe le e' ngoe e tletse ka lebokoseng la karete.

Setlhare sa Ofloxacin se fumaneha metsong ea 15 g

Ha u ntse u sebelisa litlolo, u ka hlokomela litlamorao, tse latelang:

1. Boikutlo bo tukang.
2. Ho hlohlona
3. Ho se khotsofale
4. Hyperemia.
5. Mahlo a omileng kapa lacrimation.
6. Ho se rate leseli.
7. Allergy

Litlokotsi tsa Ofloxacin li tjena:

• Allergy ho likarolo tsa moriana.
• Bana ba ka tlase ho lilemo tse leshome le metso e mehlano.
• Basali nakong ea lebone la pelehi.
• Nakong ea kemolo, ha re khothaletse tšebeliso ntle le tumello ea ngaka.

Setlolo sa mahlo bakeng sa tšebeliso ea kantle. E sebelisoa mahlo mahlong ka sekontiri sa limilimitara tse 5,10.

Mots'eare o lokela ho beoa lehloeng le ka tlase la leihlo.

Sebelisa makhetlo a mabeli kapa a mararo nakong ea lihora tse 12, ho latela mofuta oa ts'oaetso.

Maemong a chlamydia, kenya makhetlo a mahlano kapa a tšeletseng nakong ea lihora tse 12.

Matsoho a lokela ho hlatsuoa pele a kenngoa, re khothaletsa ho tšela litlolo ka leihlo ka kotloloho ho tloha mokong.

Kopo e shebahala tjena:

Tsamaisa letsoho le ka tlaase 'me u tlotse setlolo,' me u koale mahlo.

Nako ea kalafo ke libeke tse peli. Tšoaetso ea Chlamydial e hloka nako e telele ea kalafo.

Re khothaletsa hore bakhanni ba likoloi ba hane ho khanna metsotsong e 20 ea pele kamora ho sebelisoa.

Litsenyehelo tsa Russia ke li-ruble tse 35, Ukraine 16 hhucnias.

Ho na le lintlha tse 'maloa tsa mofuta ona oa lithethefatsi:

• Zitrox.
• Chloramphenicol.
• Phloxal.
• Oflomelide.
• Azitsin.
• Wilprafen.
• Vero-Ofloxacin.

Setlhare sa antibacterial sa sehlopha sa fluoroquinolone bakeng sa tšebeliso ea li-topical ho ophthalmology

Setlolo sa mahlo 0,3% e tšoeu, e tšoeu e nang le 'mala o mosehla kapa o mosehla.

Baeti: methyl parahydroxybenzoate - 0,8 mg, propyl parahydroxybenzoate - 0,2 mg, peterole - ho fihlela 1 g.

5 g - li-tubes tsa aluminium (1) - lipakete tsa karete.

Setlhare sa antibacterial se pharalletseng se tsoang sehlopheng sa fluoroquinolones bakeng sa tšebeliso ea li-topical ho ophthalmology. E sebetsa ho "encyme" ea DNA ea baktheria, e netefatsang 'mele,' me, ka hona, botsitso ba DNA ea baktheria (phetheho ea liketane tsa DNA e lebisa lefung la bona). E na le litlamorao tsa bactericidal.

E sebetsa haholo khahlano le likokoana-hloko tse ntle tsa gram: Staphylococcus spp. (ho kenyeletsoa Staphylococcus aureus, Staphylococcus epidermidis), Streptococcus spp. (ho kenyelletsa le Streptococcus pneumoniae), Likokoana-hloko tse se nang gram: Pseudomonas aeruginosa, Escherichia coli, Salmonella spp., Proteus spp. (ho kenyeletsoa Proteus mirabilis), Morganella morganii, Shigella spp., Klebsiella spp. (ho kenyeletsoa Klebsiella cloacae), Enterobacter spp., Serratia spp., Citrobacter spp., Yersinia spp., Providencia spp., Haemophilus influenzae, Neisseria gonorrhoeae, Neisseria meningitidis, Acinetobacter spp, likokoana-hloko tse ka hare-hare: Chlamydia spp. (ho kenyeletsoa Chlamydia trachomatis), Legionella spp., Mycoplasma spp., anaerobes: Propionibacterium acnes.

Ho lipatlisiso tsa liteko ho fumanoe hore kamora hore ho be le taolo ea li-topical ofloxacin e fumanoe mokokotlong (cornea), conjunctiva, mesifa ea mokokotlo, sclera, iris, 'mele oa ciliary le ka kamoreng e ka ntle ea leihlo.

Tšebeliso e pheta-phetoang e boetse e lebisa katlehong ea maikutlo a kalafo ea ofloxacin 'meleng oa vitreous. Khokahano e phahameng ea lithethefatsi e bonoa liseleng tsa leihlo ho feta mokhoabong o metsi oa leihlo.

Kamora tšebeliso e le 'ngoe ea lehare le tlotsitsoeng ka bolelele ba 1 cm (e batlang e lekana le 0,12 mg ealoxacin), Cmax ofloxacin ho conjunctiva le sclera li fihlella kamora metsotso e 5, kamora moo mahloriso a ofloxacin a fokotseha butle. Cmax ofloxacin ka har'a mongobo o metsi oa leihlo le cornea e fihleloa ka mor'a 1 h.

- mafu a baktheria ea eyelids, conjunctiva le cornea (bakteria keratitis le lisele tsa corneal, blepharitis, conjunctivitis, blepharoconjunctivitis),

- meibomite (harese), dacryocystitis,

- tšoaetso ea mahlo a mahlo,

- thibelo ea mathata a tšoaetsanoang nakong ea ts'ebetso kamora ts'ebetso ea ts'ebetso mabapi le ho tlosoa hoa mmele o kantle le likotsi tsa mahlo.

- Conjunctivitis e sa foleng ea baktheria,

- bana le bacha ba ka tlase ho lilemo tse 15,

- Hypersensitivity ho likarolo tsa lithethefatsi le tse ling tse tsoang ho quinolone.

Sebakeng sa heno. Bakeng sa leihlo le ka tlase la leihlo le amehileng makhetlo a 2-3 / letsatsi le beha karolo e le 1 cm ea mafura (0,12 mg ofloxacin). Ho tšoaetso ea chlamydial mafura a tšeloa makhetlo a 5-6 / ka letsatsi.

Ho tsamaisa moriana, hula lera le ka tlase ka hloko, 'me, o tobetsa konopo ka bonolo,' me u tšele konopo e bolelele ba 1 cm ka seleng e kopaneng. Joale koala eyelid ebe u tsamaisa leihlo la mahlo ho tsamaisa mafura ka ho lekana.

Nako ea thupelo ha e sa feta libeke tse peli (ka ts'oaetso ea chlamydial, thupelo e ekeletsoa libeke tse 4-5).

Boitšoaro ba lehae: ho felloa ke matla le ho se khotsofale mahlong, ho phunyelletsa, ho hlohlona le ho omella ha conjunctiva, photophobia, lacrimation, allergic reaction. Maemong a mangata, matšoao ana ke a nakoana.

Lintlha tse fumanehang mabapi le lithethefatsi tse fetang tekano ha li fanoe.

Ha u fana ka taelo ea Ofloxacin, hammoho le marotholi a mang a mahlo / litlolo, lithethefatsi li lokela ho sebelisoa le bonyane metsotso e 15, eo Ofloxacin e lokelang ho sebelisoa ho eona.

Se ke oa roala lilense tse bonolo tsa puisano nakong ea kalafo le moriana.

Ho khothalletsoa ho roala likhalase (ka lebaka la nts'etsopele ea Photophobia), le ho qoba ho chabeloa ke khanya e telele nako e telele.

Ofloxacin ha ea lokela ho tsamaisoa ka mokhoa o ikhethileng kapa ka kamoreng e ka ntle ea leihlo.

Tšusumetso ho bokhoni ba ho khanna makoloi le litsamaiso tsa taolo

Hang ka mor'a ho sebelisa lithethefatsi, ho ba le pono e fifalitsoeng ea pono ho ka etsahala, ho ka lebisang mathateng ha o khanna le ha o sebetsa ka mekhoa. Ho khothalletsoa ho qala mosebetsi (ho khanna) metsotso e 15 kamora ho sebelisa lithethefatsi.

Bokhachane le pelehi

Ts'ebeliso ea lithethefatsi e patiloe ho

le nakong ea ho anyesa.

Sebelisa bongoaneng

Setlhare sena se kopantsoe ho bana le bacha ba ka tlase ho lilemo tse 15.

Setlhare ke ngaka.

Lenane B. Lithethefatsi li lokela ho bolokoa li sa fihlelloe ke bana ka mocheso oa 15 ° ho isa ho 25 ° C. Bophelo ba Shelf ke lilemo tse 3.

Tlhahlobo ea lingaka

Tlhahlobo ea lingaka e tla thusa ho utloisisa phello ea moriana ts'ebetsong:

Eugene, therapist: Hangata bakuli ba tla ka tlhahlobo ea harese. Lefu lena le sa thabiseng le tobane le batho ba bangata ba lilemo tse fapaneng. Bakeng sa kalafo, hangata ke khothaletsa setlolo sa mafura sa Ofloxacin ho bakuli. Setlhare se theko e tlaase ebile se sebetsa. Maemong a joalo e hlahisa phello e hlokahalang ea antibacterial. Ts'ebetsong ea ka, ho ne ho se na litlhahlobo tse mpe.

Yuri, setsebi sa mahlo a mahlo: Setlhare ke lithethefatsi tse tsebahalang tse theko e tlaase. Khafetsa e hlalosoa e le kalafo e rarahaneng bakeng sa lisele tsa baktheria. Ho sebetsa hantle ho bonoa ka chlamydia ea mahlo. Phekolo ke ea nako e telele, empa e sebetsa. Maemong a mangata, e mamelloa hantle 'me ha e bake maemo a mabe.

Alexander, ophthalmologist: Setlhare se sebetsa hantle lits'ebetsong tsa ho ruruha le liso tsa baktheria. Ke fana ka kalafo e rarahaneng bakeng sa kalafo ea blepharitis, conjunctivitis, harese. Hangata bakuli ha ba tletlebe ka phello ea mafura.

Tlhahlobo ea bareki

Tlhahlobo ea bakuli ba ileng ba phekoloa ka moriana ona:

Julia, ea lilemo li 35: Ngaka e ile ea eletsa hore ho tšeloe oli ka harese. Pimple e ile ea buloa matsatsi a mabeli kamora ho hlaha. Setlolo sena se ile sa thusa ho sireletsa leihlo hore le se ke la bolaoa ke bacteria. Ha ho na karabelo e mpe e etsahetseng. Ke rata hore moriana o theko e tlase ebile o theko e tlase. Ha kea ka ka nka meriana e meng nakong ea kalafo.

Nadezhda, ea lilemo li 28: O tobane le lefu le bohloko joalo ka blepharitis. Ngaka ea mahlo e ile ea laela kalafo e rarahaneng. E kenyelletsa ho kenngoa ha setlolo sa Ofloxacin. Tsamaiso ea ho rala ha e monate haholo. Ka nakoana ke ne ke lahlehetsoe ke pono, lintho tsohle li na le maru. Ha e le hantle ka mor'a metsotso e ka bang 20, ntho e 'ngoe le e' ngoe e ile ea khutlela sebakeng sa eona.

Igor ea lilemo li 37: Setsebi sa mahlo sa mahlo se laetse setlhare e le kalafo e rarahaneng ea bacterium conjunctivitis. Pele, ke ne ke lumela hanyane ka matla ts'ebeliso ea moriana o theko e tlase joalo. Kamora matsatsi a 5, lahla ho ruruha. Laela mafura kamora ho sebelisa marotholi a mahlo. Ke ratile hore, ho fapana le lithethefatsi tse ling, mafura ana a theko e tlaase. Matšoao a sa thabiseng le litlamorao ha lia ka tsa etsahala nakong ea kalafo.

Litaelo tsa litlolo tsa leihlo la Ofloxacin bakeng sa tšebeliso

Setlolo sena se entsoe ka mokhoa oa ho loants'oa le litšoaetso tsa ts'oaetso le ts'oaetso sebakeng sa leihlo. Kenya litlolo ka:

1. Harese.
2. Conjunctivitis.
3. Tšoaetso ea Chlamydial ea mahlo.
4. Blepharitis.
5. Pathology ea eyelids.
6. Pathology ea cornea.

Setlolo sena se sebelisoa e le prophylactic, moo ho nang le tšoaetso ea mafu, mathata a ka mor'a ho buuoa ka mor'a ho ntšoa 'mele o tsoang ka ntle mahlong kapa tšenyehong e koahelang mahlo.

Likheo tse amanang

Setlolo sena ha se theko e boima ebile sea sebetsa. Empa ho hlokahala ho etsa kopo ka tieo ho latela litaelo, ho seng joalo, kamora ho phomola ha nakoana matšoao, ts'ebetso ea ho ruruha e ka mpefala. Ena ke tšobotsi ea lithibela-mafu. Ha e le li-analogues, ha se lintho tsohle tse kaholimo tse nang le ntho e le 'ngoe e sebetsang ka sebopeho sa bona le oli ea Ofloxacin. Mohlala, chloramphenicol ke mofuta o mong oa lithibela-mafu. Joale na phello ea kalafo e tla tšoana? Ha se 'nete.

Ketso ea pharmacological

Lihoai: moemeli oa antimicrobial - fluoroquinolone.
Ketso ea litlhare: Moemeli ea sebetsanang le li-antimicrobial tse tsoang sehlopheng sa fluoroquinolones, o sebetsa ho ligrase ea enzyme ea DNA, e fanang ka supercoiling, jj. botsitso ba DNA ea baktheria (ho etsa hore liketane tsa DNA li lebise lefung la bona). E na le litlamorao tsa bactericidal.
E na le ts'ebetso ho vivo: li-aerobes tse ntle tsa gram: Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae. Li-aerobes tsa Gram-negative: Enterobacter koae, tšusumetso ea Haemophilus, Proteus mirabilis, Pseudomonas aeruginosa, Serratia marcescens.Anaerobes: Propionibacterium acnes.
Litlhaselo tse kenang habonolo: li-aerobes tse ntle tsa gram: Enterococcus faecalis, Staphylococcus hominus, Listeria monocytogene, Staphylococcus simulans, Staphylococcus capitis, Streptococcus pyogene. Li-aerobes tse se nang gram: Acinetobacter calcoaceticus var. anitratus, Klebsiella pneumoniae, Acinetobacter calcoaceticus var. lwoffii, Moraxella (Branhamella) catarrhalis, Citrobacter diversus, Moraxella lacunata, Citrobacter freundii, Morganella morganii, Enterobacter aerogene, Neisseria gonorrhoeae, Enterobacter agglomerans, Pseudomonas acidovorans, Escherichomella cholefenella pheudis coli heli
Tse ling: Chlamydia trachomatis.

Setlolo sa Ofloxacin, matšoao a ts'ebeliso

Ophthalmology: Bacteric corneal ulcers, conjunctivitis, blepharitis, meibomite (barele), dacryocystitis, keratitis, tšoaetso ea chlamydial ea mahlo, thibelo ea mathata a tšoaetsanoang nakong ea ts'ebetso kamora ho sebetsoa bakeng sa ho tlosoa ha mmele o kantle le likotsi tsa mahlo.
Boikoetliso ba ENT: Lik'homphieutha tsa otitis tse mpe tse sa feleng le tse bohareng, mecha ea litaba ea otitis e nang le oli eardrum kapa tympanopuncture e thibelang mathata a tšoaetsanoang nakong ea ts'ebetso ea bongaka.

Tekanyetso le tsamaiso

Sebakeng sa heno. Bakeng sa leihlo le ka tlase la leihlo le amehileng makhetlo a 2-3 / letsatsi le beha karolo e le 1 cm ea mafura (0,12 mg ofloxacin). Ka tšoaetso ea chlamydial, mafura a tšeloa makhetlo a 5-6 / ka letsatsi.

Ho tsamaisa moriana, hula lera le ka tlase ka hloko, 'me, o tobetsa konopo ka bonolo,' me u tšele konopo e bolelele ba 1 cm ka seleng e kopaneng. Joale koala eyelid ebe u tsamaisa leihlo la mahlo ho tsamaisa mafura ka ho lekana.

Nako ea thupelo ha e sa feta libeke tse peli (ka ts'oaetso ea chlamydial, thupelo e ekeletsoa libeke tse 4-5).

Litlhokahalo tsa polokeho

Nako eohle ea nako ea kalafo ha e fetang likhoeli tse peli. Qoba ho pepesetsoa khanya ea letsatsi le mahlaseli a UV.

Tabeng ea nts'etsopele ea litlamorao ho tsoa ho tsamaiso ea methapo e kholo, ho kula hohle, pseudomembranous colitis, ho hlokahala hore ho tlosoe lithethefatsi. Le pseudomembranous colitis, proven colonoscopically le / kapa histologically, tsamaiso ea molomo ea vancomycin le metronidazole e bontšoa.

Ho hlaha ha tendonitis hangata ho ka lebisa ho phatloha ha tendon (haholo-holo tendon ea Achilles), haholoholo ho bakuli ba tsofetseng. Mabakeng a matšoao a tendonitis, ho hlokahala hore o emise kalafo hanghang, a thatafatse tendon ea Achilles mme o buisane le orthopedist.

Bakeng sa bakuli ba nang le bothata ba ho ruruha ba mokokotlo kapa ho ba le hepatic, ho lokela ho be leihlo leihlo la pherekano ka plasma. Ka lebaka la khaello e matla ea renal le hepatic, menyetla ea ho ba le chefo e ea eketseha.

Ofloxacin

Matlapa a tlotsitsoeng ka filimi ea 200 mg - lilemo tse 5.

Letlapa le koahetsoeng ka filimi ea 400 mg - lilemo tse 5.

setlolo sa leihlo 0,3% - lilemo tse 5. Kamora ho bula - libeke tse 6.

Tharollo ea infusion ea 2 mg / ml ka tharollo ea 0,9% ea sodium chloride - lilemo tse 2.

Se ke oa sebelisa kamora letsatsi la ho felloa ke nako le bontšitsoeng ka har'a sephutheloana.