Matlapa a Emoxipin: litaelo tsa hore li sebelisoe

Emoxipine (INN - Emoxipine) ke angioprotector e fokotsang boemo ba methapo ea methapo ka lebaka la ho potlakisa ha ts'ebetso ea mahala ea ramatiki, le eona lithethefatsi ke antioxidant le antihypoxant. Emoxipin e tla fokotsa phallo ea mali, masapo a methapo ea methapo le tšekamelo ea ho ruruha. Ntle le moo, lintho tse sebetsang tsa moriana li tla eketsa boemo ba litaba cyclic nucleotides ka lisele tsa bokong le liplatelete tsa mali.

Ketsahalo ea Fibrinolytic ea lithethefatsi e bonahala ka taba ea hore maemong a nako a hlobaetsang lefu la pelo, mokhoa o khona ho holisa likepe tsa coronary, ka ho etsa joalo o fokotsa mohopolo o ntseng o ntlafala necrosis. Hape, bokhoni ba pelo bo botle ba ho etsa lintho ka lehare bo tla ntlafala.

Ha e le ntho ea mahlo, Emoxipin e na le thepa eo e ka e sebelisang hape e sirelletsa "retina" ts'ebetsong ea mahlaseli a khanya a phahameng. Drops of Emoksipin e tla thusa ho rarolla hemorrhage ea methapo le ho ntlafatsa ts'ebetso ea microcone leihlo.

Pharmacodynamics le pharmacokinetics

Mofumahali

Tšusumetso e ntle ho coagulation: ka ho fokotsa lenane la coagulation ka kakaretso le ho fokotsa pokello ea liplatelese, sethethefatsi se eketsa nako ea ho kopanya mali. Lerale tsa lisele le methapo ea mali tlas'a ts'ebetso ea lithethefatsi li tiisa, lisele tse khubelu tsa mali eketsa ho hanyetsa ha tsona hemolysis le likotsi tse ka 'nang tsa hlaha.

Thibelo e sebetsang ea li-oxidation tsa mahala tsa lipidale tse fumanehang biomembranes. Ho eketsa ts'ebetso ea li-enzyme tse ikarabellang bakeng sa ts'ebetso ea antioxidant. O khona ho fana lipid-lowing effect ka ho fokotsa mofuta oa triglycerides.

Kamohelo ea Emoksipin e khona ho fokotsa lipontšo hemodysfunction. E na le phello e ntle ho botsitso ba cortex ea "cerebral" ho ischemia le hypoxia. Ho lokisa dysfunctions tsa Autonomic maemong a kotsi ea methapo ea pelo.

Emoxipin e na le phello e phatlalalitsoeng ea pelo. Ts'ebetso ea pelo le pelo e tla sireletsoa haeba myocardial ischemic: Lithethefatsi li thibela phetisetso ea tsona, hape e holisa likepe tsa coronary.

Joalo ka leitlho Emoxipin e sireletsa retina hore e se ke ea senyeha ka lebaka la mahlaseli a khanya a matla. Ntle le moo, ka lebaka la sethethefatsi, ho ts'oaroa ha hemorrhages kahare ho leihlo hoa khoneha.

Mofumahali

Tabeng ea tekanyetso ea methapo e kenang ea 10 mg ka kilo e le 'ngoe ea boima ba mokuli, ho lemohuoa boemo bo tlase haholo Ho felisoa ha moriana. Ho felisoa khafetsa ke 0,041 min, moqolo o hlakileng oa kabo ke 5.2 l, botlalo ba tumello ke 214.8 ml ka motsotso.

Setlhare sena se kenella ka hare ho litho le lisele tsa 'mele oa motho, ke sona hantle se etsahalang metabolism.

Li-pharmacokinetics tsa Emoxipin li ka fapana ho latela boemo ba mokuli. Mohlala, maemong a boemo ba pathological coronary occlusion, lebelo leo moriana o hlahisoang ka lona le tla fokotsoa, e le hore e ka ba le bioava haholoanyane.

Tabeng ea ho khutlisa tsamaiso ea Emoxipine, metsoako e sebetsang ea lithethefatsi e hlaha hang-hang maling, boemo bo tsitsitseng bo phehellang lihora tse peli, mme kamora lihora tse 24 kamora ts'ebetso, tsamaiso ea tsamaiso e batla e le sieo ka botlalo maling. Karolo e itseng ea lithethefatsi e bolokiloe liseleng tsa mahlo.

Matšoao a ts'ebeliso ea Emoxipin

Joalo ka leitlho Matšoao a sebelisoang ke:

hemorrhage ea methapo,
thrombosis ka har'a mothapo o moholo oa leihlo le makala,
glaucoma,
ts'ireletso ea retina kamora laser coagulation le khanya e phahameng (boemong ba ho chesoa ke letsatsi le laser).

Matšoao a ho sebelisoa Liente tsa Emoxipin:

Hape, ente ea Emoxipin e sebelisoa ha ho sa felle ka nako e telele haholo ho potoloha ha bokohaeba sesosa sa mathata ana ke maloetse a hemorrhagic le ischemic. Haeba ho hlokahala, moriana o ka tsamaisoa ka ente ea intramuscular, kapa e le ente ea intravenous ho ampoules.

Litlamorao

Ho ka hlaha mefuta e fapaneng tsosaeo kamora nako e kgutshwane e tla nkelwa sebaka ho otsela. Mohlomong keketseho ea khatello ea mali le ponahalo makhopho. Boitšoaro ba lehae bo ka bonahatsoa ke bohloko, ho hlohlona, ho chesa maikutlo, bofubelu le ho tiisa lisele tsa paraorbital.

Litaelo tsa ts'ebeliso ea Emoxipin (Mokhoa le litekanyetso)

Litaelo bakeng sa Emoxipin - marotholi a mahlo

Tabeng ea ho khutlisa tsamaiso ea lithethefatsi, tharollo ea karolo e le 'ngoe ka tekanyetso ea 0.5 ml e fanoa ka nako e le ngoe ka letsatsi bakeng sa matsatsi a 10-15. Haeba moriana o fanoa ka subconjunctival le parabulbar, joale ho tloha ho 0,5 ho isa ho 0,5 ml ea moriana o fanoa hang ka letsatsi bakeng sa matsatsi a 10-30.

Haeba ho hlokahala ho sireletsa retina ea ocular, moriana o tsamaisoa ka mokhoa o khutlang ka tekanyetso ea 0.5 di ml ka letsatsi le hora e le ngoe pele ho soahlana ha laser. Thupelo ena e ipapisitse le boemo ba ho chesoa ha laser, ka makhetlo a mangata, marotholi a sebelisoa hang ka letsatsi ho tloha matsatsing a mabeli ho isa ho a leshome.

Litaelo bakeng sa Emoxipin - ente

Ho "cardiology" le "psychology", "lithethefatsi li sebelisoa ka mokhoa o ikhethileng ka sekhahla sa marotholi a 2040 ka motsotso. Tekanyetso ea lithethefatsi ke 20-30 ml ea tharollo ea liperesente tse tharo. Li-Dropper li ka fanoa ho tloha makhetlo a mararo ho isa ho a mararo ka letsatsi bakeng sa matsatsi a 5-15. Nako ea kalafo e latela mofuta oa lefu la mokuli. Qetellong ea li-droppers, ba chenchana le liente tsa methapo ea lithethefatsi: li-3-5 ml tsa tharollo ea 3% li kenngoa makhetlo a 2-3 ka letsatsi. Nako ea ente ea intramuscular e tsoa matsatsing a 10 ho isa ho a 30.

Emoxipin ha e lokolloe kahare foromo ea letlapa, hobane u ke ke ua nka matlapa a Emoxipin, hobane a teng.

Bongata

Haeba ho na le lithethefatsi tse ngata tsa lithethefatsi, ponahalo kapa matla a litla-morao a ka etsahala. Ka moriana o feteletseng oa lithethefatsi kapa li-analogues tsa eona, e ka eketseha khatello ea maliho ruruha ho feteletseng kapa ho otsela, bohloko bo ka pelong, hlooho e bohloko, ho nyekeloaho opeloa ke mpa. Ho ruruha ha mali ho kanna ha ba haella.

Phekolo ea overdose ea Emoxipin le li-analogues tsa Emoxipin ke ho khaotsa lithethefatsi le ho tsamaisa mekhoa ea kalafo ea matšoao, haeba ho hlokahala.

Tšebelisano

Boemong ba kopo hammoho α-tocopherol acetate, mohlomong pontsho e sebetsang haholoanyane ea thepa ea antioxidant ea Emoxipin. Ka kakaretso, ho sebelisa moriana ona ha ho khothalletsoe ho kopantsoe le tšebeliso ea lithethefatsi tse ling ntle le tumello ho ngaka e eang.

Mofumahali

Ha o tsamaisoa ka tekanyetso ea 10 mg / kg, nako ea ho felisoa ha halofo ea Ti / g ke metsotso e 18, netefatso e felletseng ea CI ke 0,2 l / min, mme bophahamo bo bonahalang ba kabo ea Vd ke 5.2 l.

Setlhare sena se kenella ka hare ho litho le lisele, moo se behoang le ho kenngoa ts'ebetsong. Ho fumanoe li-metabolites tse hlano tsa emoxipin, tse emeloang ke lihlahisoa tse litšila le tse kopantsoeng tsa phetoho ea tsona. Li-metabolite tsa Emoxipin li epolloa ke liphio. Palo ea bohlokoa ea 2-ethyl-6-methyl-3-hydroxypyridine-phosphate e fumanoa ka har'a sebete.

Maemong a pathological, ho etsa mohlala, maemong a corlary occlusion, pharmacokinetics ea emoxipin changes. Sekhahla sa li-excretion sea fokotseha, nako e sebelisitsoeng ke emoxipin maling a eketseha, e ka bang ka lebaka la ho khutla ha hae ho tsoa depong, ho kenyeletsoa ho tsoa ho ischemic myocardium.

Letsatsi la ho felloa ke nako

Lilemo tse 3 ho tloha ka letsatsi leo a lokolloang ka lona.

Emoxipin ke pheko ea sejoale-joale e sebetsang. Ntho feela e khahlang ke ho halefisoa ha lehae ha ho sebelisoa. Batho ba tobaneng le mafu a mahlo a tebileng ba tlohela tlhahlobo e ntle haholo mabapi le Emoxipine, hobane ba latela litaelo tsa ngaka ka tieo, mme ka lebaka la bothata, ba amohela ka ho hlaka tlhokahalo ea kalafo. Haeba moriana o sebelisetsoa kalafo ea mafu a mahlo a fokolang, litlhahlobo mabapi le marotholi li ke ke tsa ba ntle haholo: 'nete ke hore ha se motho e mong le e mong ea ikemiselitseng ho mamella maikutlo a mabe a tukang a sa thabiseng kamora ho sebelisa moriana.

Lingaka li hlahloba ka leitlho - e ntle haholo. Setlhare sena se sebetsana le mosebetsi oa sona, leha se baka tsitsipano ea nakoana ho bakuli.

Likokoana-hloko tsa Emoxipin sebetsana ka katleho le litlamorao tsa lichapo le ho nyekeloa ke pelo ho bakuli ba bangata lefatseng ka bophara. Hape, ho sebelisa moriana ona ka nako e khuts'oane ho thusa ho fokotsa lipontšo tsa mathata a methapo ea kutlo. Hoa utloahala hore boiphihlelo bo joalo bo nepahetseng ba tšebeliso bo bontšoa litlhahlobong tse ntle, ho tsoa ho bakuli le ho lingaka.

Theko ea Emoxipin, ho reka

O ka reka Emoxipin ho la Kiev ntle le mathata: sethethefatsi kapa li-analogues tsa sona se ka fumaneha ho hoo e ka bang lithekeng tsohle. Ke feela litšenyehelo li ka fapana hanyane ho latela phapusi ea meriana, leha ho le joalo, hoo e batlang e le litheko tsohle tsa mahlo Ukraine, le lithethefatsi tse ling li fapana ka theko. Ha hoa itšetleha feela ka moeli oa k'hemiste ka moriana, empa hape le sebakeng sa tlhahiso ea sona, tokollo e ngata, jj.

Theko ea karolelano leihlo le oela emoxipin 1% ka botlolong ea 5 ml e fetoha 'marakeng ho pota 60 UAH. Pakete ea li-ampoule tse hlano 1 ml ea karolo e le 'ngoe ea Emoksipin No. 10 e tla bitsa UAH e 50 ka har'a k'hemiste.