Metfogamm 1000: litaelo tsa tšebeliso, theko, litafole tsa tsoekere
Metfogamm 1000 (matlapa) Tekanyetso: 8
Moetsi: Vörwag Pharma GmbH & Co KG (Jeremane)
Mefuta ea Tsamaiso:
- Matlapa a 1000 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 176
Litaelo tsa ho sebelisoa
Setlhare se seng sa lefu la tsoekere ka tokollo ea foromo. E rekisitsoe ka har'a lipakete tsa likarete tsa 30 tse nang le metformin hydrochloride e le motsoako o sebetsang. Contraindred nakong ea bokhachane le nakong ea matsoele.
Theko le molao-motheo oa ts'ebetso ea moriana
Setlhare ke bokae? Theko e ipapisitse le palo ea metformin ea lithethefatsi. Bakeng sa Metfogamma 1000 theko ke li-ruble tse 580-640. Metfogamm 500 mg e bitsa li-ruble tse ka bang 380-450. Ho Metfogamma 850 theko e qala ho tloha ho li-ruble tse 500. Ho bohlokoa ho tseba hore meriana ena e fuoa feela ka taelo ea ngaka.
Ba etsa meriana Jeremane. Ofisi ea baemeli e molaong e Moscow. Ka 2000s, tlhahiso ea meriana e thehiloe toropong ea Sofia (Bulgaria).
Molao-motheo oa ts'ebetso ea lithethefatsi o thehiloe ho eng? Metformin (motsoako o sebetsang oa lithethefatsi) e fokotsa bongata ba tsoekere maling. Sena se fihlelloa ka ho hatella gluconeogeneis ka har'a sebete. Metformin e boetse e ntlafatsa ts'ebeliso ea tsoekere ho linama 'me e fokotsa ho monya ha tsoekere ho tsoa ho tšilo ea lijo.
Hoa hlokomeleha hore ha u sebelisa moriana, boemo ba cholesterol le LDL serum ea mali boa fokotseha. Empa Metformin ha e fetole bongata ba lipoprotein. Ha o sebelisa moriana o ka fokotsa boima ba 'mele. Ka tloaelo, ho sebelisoa metogram e 500, 850, le 100 mg ha ho ja ho sa thusa ho fokotsa boima ba 'mele.
Metformin ha e theole tsoekere ea mali feela, empa hape e ntlafatsa haholo likarolo tsa mali tsa fibrinolytic.
Sena se fihlelloa ka ho hatella mofuta oa mofuta oa "plasminogen inhibitor".
Litaelo tsa tšebeliso ea lithethefatsi
Ke maemong afe moo ts'ebeliso ea lithethefatsi tsa Metfogamm 500 e nang le mabaka? Litaelo tsa tšebeliso li re moriana o lokela ho sebelisoa kalafong ea lefu la tsoekere la mofuta o mong o sa itšetleheng ka insulin. Empa Metfogamma 1000, 500 le 800 mg e lokela ho sebelisoa kalafong ea bakuli ba sa tloaeloang ke ketoacidosis.
U ka e sebelisa joang? Litekanyetso li khethoa ho latela boemo ba glucose maling. Ka tloaelo, tekanyetso ea pele ke 500-850 mg. Haeba moriana o sebelisoa ho boloka maemo a tloaelehileng a tsoekere, joale tekanyetso ea letsatsi le letsatsi e ka nyolohela ho 850-1700 mg.
O hloka ho nwa moriana o noang ka tekanyetso e 2 e arohaneng. Ke lokela ho nka moriana nako e kae? Bakeng sa Metfogamma 850, thuto ha e laole hore na nako ea phekolo e joang. Nako ea kalafo e khethoa ka bonngoe mme ho latela lintlha tse ngata.
Ho Metfogamma 1000, litaelo tsa tšebeliso ea melaoana ea tšebeliso li ka sebelisoa.
- Lefu la tsoekere la ketoacidosis.
- Ho tlosoa ha liphio.
- Ho nyekeloa ke pelo.
- Kotsi ea methapo.
- Bokhoba ba tahi bo sa feleng
- Ho omella.
- Karolo e mpe ea infarction ea myocardial.
- Ho se sebetse ha sebete.
- Chefo ea joala.
- Lactic acidosis
- Boimana
- Nako ea ho anyesa.
- Allergy ho metformin le likarolo tse thusang tsa lithethefatsi.
Tlhahlobo ea lingaka e bonts'a hore moriana ona ha oa lokela ho sebelisoa nakong ea lijo tse nang le khalori e tlase, e kenyelletsang tšebeliso ea likhalori tse ka tlase ho 1000 ka letsatsi. Ntle le moo, sethethefatsi Metfogamm 1000 se ka baka mathata a tebileng, ho fihla ho lefu la tsoekere.
Hangata moriana o mamelloa hantle ke bakuli. Empa ka tšebeliso ea nako e telele ea lithethefatsi, menyetla ea litla-morao e kang:
- Megaloblastic anemia.
- Ho tlola mosebetsi mosebetsing oa tšilo ea lijo. Metfogamma 1000 e ka baka nts'etsopele ea matšoao a dyspeptic, ho nyekeloa le pelo, ho hlatsa le lets'ollo. Hape nakong ea kalafo ea kalafo, tatso ea tšepe e ka hlaha molomong.
- Hypoglycemia
- Lactic acidosis.
- Litla-morao.
Nts'etsopele ea lactic acidosis e bonts'a hore ho molemo ho sitisa tsela ea kalafo.
Haeba mathata ana a hlaha, kalafo ea matšoao e lokela ho nkuoa hang-hang.
Tšebelisano ea lithethefatsi le li-analog tsa lithethefatsi
Metfogamma 1000 e sebetsana joang le lithethefatsi tse ling? Litaelo li re meriana e ka fokotsa katleho ea kalafo ka ts'ebeliso ea li-anticoagulants.
Ha ho kgothaletswe ho sebelisa moriana oa lefu la tsoekere hammoho le li-inhibitors tsa MAO, li-inhibitors tsa ACE, li-derifatives tse tsoang ho tsona, li-cyclophosphamides kapa beta-blockers. Ka tšebelisano ea metformin le lithethefatsi tse ka holimo, menyetla ea ts'ebetso ea hypoglycemic e eketseha.
Litekanyetso tse atlehang ka ho fetisisa tsa Metfogamma 1000 ke life? Ho latela lingaka, mefuta e molemohali ke ena:
- Glucophage (li-ruble tse 220-400). Setlhare sena se hantle joalo ka Metfogamma. Karolo e sebetsang ea lithethefatsi ke metformin. Moriana ona o thusa tsoekere e tlase ea mali le ho eketsa tlhaloganyo ea li-receptor tsa insulin.
- Glibomet (li-ruble tse 320-480). Moriba o thibela lipolysis ka har'a lithane tsa adipose, o tsosa maikutlo a phello ea litho tsa botšehali ketsong ea insulin mme o fokotsa tsoekere ea mali.
- Siofor (li-ruble tse 380-500). Lithethefatsi li thibela ho kenngoa ha tsoekere ka bongata ka mpeng, e ntlafatsa ts'ebeliso ea tsoekere liseleng tsa mesifa le ho fokotsa tlhahiso ea tsoekere maling.
Mekhoa ea meriana e kaholimo e khothalletsoa hore e sebelisoe le lefu la tsoekere la 2 le sa ts'epeng insulin. Ha u khetha analogue, o lokela ho botsa ngaka ea hau, kaha lithethefatsi tsa ho fokotsa tsoekere li ka baka lactic acidosis. Video e sehloohong sena e tsoela pele sehlooho sa ho sebelisa Metformin bakeng sa lefu la tsoekere.
Analogs ea lithethefatsi Metfogamm 1000
Analogue e theko e tlaase ho tloha li-ruble tse 66.
Moetsi: Merck Sante SAA.S. (Fora)
Mefuta ea Tsamaiso:
- Matlapa a 500 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 110
- Matlapa a 1000 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 185
Litaelo tsa ho sebelisoa
Lithethefatsi tsa Mafora bakeng sa kalafo ea lefu la tsoekere la mofuta oa 2. E rekisitsoe matlapeng a nang le 500 ho isa ho 1000 mg ea metformin e le eona feela motsoako o sebetsang. Ho na le li-contraindication, ka hona, pele ho nka Glucofage, ho bohlokoa ho buisana le setsebi.
Analogue e theko e tlase ho li-ruble tse 67.
Moetsi: Akrikhin (Russia)
Mefuta ea Tsamaiso:
- Matlapa a 500 mg, li-pcs tse 60., Theko e tsoang ho li-ruble tse 109
- Letlapa 850 mg, li-pcs tse 60., Theko e tsoang ho li-ruble tse 190
Litaelo tsa ho sebelisoa
Gliformin ke sethethefatsi sa lapeng ho phekoloa lefu la tsoekere la mofuta oa 2. A rekisoa ka mokhoa oa litafole tse nang le metformin e le eona feela motsoako o sebetsang (litekanyetso tsa 250 kapa 500 mg li ka etsahala). Gliformin e na le lethathamo le pharaletseng la li-contraindication, kahoo pele o qala kalafo, etsa bonnete ba ho bala litaelo tsa semmuso bakeng sa tšebeliso.
Analogue e theko e tlaase ho tsoa li-ruble tse 119.
Moetsi: Pharmstandard-Leksredstva (Russia)
Mefuta ea Tsamaiso:
- Tab. 50 mg, li-pcs tse 30., Theko e tsoang ho li-ruble tse 57
- Tab. 50 mg, li-pcs tse 60., Theko e tsoang ho li-ruble tse 99
Litaelo tsa ho sebelisoa
Formetin ke ntho e sa bitseng chelete e ngata bakeng sa Glucofage, e etselitsoeng ho theola tsoekere e maling. E fumaneha matlapeng a nang le 0.5, 0,85 kapa 1 g ea metformin. E ka baka mathata a tsamaiso ea methapo ea lijo, lekhopho la letlalo, mme haeba ho ka ba le overdose - hypoglycemia le lactic acidosis ka sephetho se bolaeang.
Analog e theko e phahameng haholo ho tsoa li-ruble tse 2.
Moetsi: Hemofarm A.D. (Serbia)
Mefuta ea Tsamaiso:
- Tab. 500 mg, li-pcs tse 60., Theko e tsoang ho li-ruble tse 178
- Tab. 50 mg, li-pcs tse 60., Theko e tsoang ho li-ruble tse 99
Litaelo tsa ho sebelisoa
Metformin ke lithethefatsi tsa Serbia hypoglycemic bakeng sa tšebeliso ea kahare. Ho hlophisoa ha matlapa ho na le motsoako o sebetsang oa lebitso le tšoanang ho litekanyetso tsa 500 kapa 850 mg. E laetsoe kalafo ea lefu la tsoekere la mofuta oa 2 (ho batho ba baholo), haholoholo maemong a botenya.
Analogue e theko e phahameng haholo ho tloha ho li-ruble tse 209.
Moetsi: Kimika Montpellier S.A. (Argentina)
Mefuta ea Tsamaiso:
- Matlapa a 1000 mg, li-pc tse 60., theko ho tloha li-ruble tse 385
- Tab. 50 mg, li-pcs tse 60., Theko e tsoang ho li-ruble tse 99
Litaelo tsa ho sebelisoa
Letlapa la matlapa la Argentina bakeng sa kalafo ea lefu la tsoekere. Ketso ea Bagomet e ipapisitse le tšebeliso ea metformin hydrochloride ka bongata ba 500 mg ka ho penta. E fuoe lefu la tsoekere la mofuta oa 2.
Li-analog mabapi le sebopeho le pontšo ea ts'ebeliso
| Sehlooho | Theko ho la Russia | Theko Ukraine |
|---|---|---|
| Bagomet Metformin | -- | 30 UAH |
| Glucofage metformin | 12 rub | 15 UAH |
| Glucophage xr metformin | -- | 50 UAH |
| Reduxin Met Metformin, Sibutramine | 20 rub | -- |
| Dianormet | -- | 19 UAH |
| Diaformin metformin | -- | 5 UAH |
| Metformin metformin | 13 rub | 12 UAH |
| Metformin sandoz metformin | -- | 13 UAH |
| Siofor | 208 rub | 27 UAH |
| Foromo metformin hydrochloride | -- | -- |
| Emnorm EP Metformin | -- | -- |
| Megifort Metformin | -- | 15 UAH |
| Metamine Metformin | -- | 20 UAH |
| Metamine SR Metformin | -- | 20 UAH |
| Tefor metformin | -- | -- |
| Glycometer | -- | -- |
| Glycomet SR | -- | -- |
| Forthine | 37 rub | -- |
| Metformin Canon metformin, ovidone K 90, starch ea poone, crospovidone, magnesium stearate, talc | 26 rub | -- |
| Insuffor metformin hydrochloride | -- | 25 UAH |
| Metformin-teva metformin | 43 rub | 22 UAH |
| Diaformin SR metformin | -- | 18 UAH |
| Mepharmil Metformin | -- | 13 UAH |
| Metformin Farmland Metformin | -- | -- |
Lethathamo le ka holimo la li-analogues tsa lithethefatsi, tse bonts'ang metfogammohammr, e loketse haholo hobane e na le sebopeho se tšoanang sa lintho tse sebetsang ebile e lumellana ho latela sesupo sa tšebeliso
Moetso o fapaneng o kanna oa lumellana ho bonts'a mokhoa le mokhoa oa kopo
| Sehlooho | Theko ho la Russia | Theko Ukraine |
|---|---|---|
| Rosiglitazone e sebetsang, metformin hydrochloride | -- | -- |
| Glibenclamide Glibenclamide | 30 rub | 7 UAH |
| Maninyl Glibenclamide | 54 rub | 37 UAH |
| Glibenclamide-Health Glibenclamide | -- | 12 UAH |
| Glyurenorm glycidone | 94 rub | 43 UAH |
| Bisogamma Glyclazide | 91 rub | 182 UAH |
| Glidiab Glyclazide | 100 rub | 170 UAH |
| Diabeteson MR | -- | 92 UAH |
| Diagnizide mr Gliclazide | -- | 15 UAH |
| Glidia MV Gliclazide | -- | -- |
| Glykinorm Gliclazide | -- | -- |
| Gliclazide Gliclazide | 231 rub | 44 UAH |
| Glyclazide 30 MV-Indar Glyclazide | -- | -- |
| Glyclazide-Health Gliclazide | -- | 36 UAH |
| Glioral Glyclazide | -- | -- |
| Lekola Gliclazide | -- | 14 UAH |
| Diazide MV Gliclazide | -- | 46 UAH |
| Osliklid Gliclazide | -- | 68 UAH |
| Diadeon gliclazide | -- | -- |
| Glyclazide MV Gliclazide | 4 rub | -- |
| Amaril | 27 rub | 4 UAH |
| Glemaz glimepiride | -- | -- |
| Glian glimepiride | -- | 77 UAH |
| Glimepiride Glyride | -- | 149 UAH |
| Glimepiride diapiride | -- | 23 UAH |
| Aletare | -- | 12 UAH |
| Glimax glimepiride | -- | 35 UAH |
| Glimepiride-Lugal glimepiride | -- | 69 UAH |
| Clay glimepiride | -- | 66 UAH |
| Diabrex glimepiride | -- | 142 UAH |
| Meglimide glimepiride | -- | -- |
| Melpamide Glimepiride | -- | 84 UAH |
| Perinel glimepiride | -- | -- |
| Glempid | -- | -- |
| Ke thabo | -- | -- |
| Glimepiride glimepiride | 27 rub | 42 UAH |
| Glimepiride-teva glimepiride | -- | 57 UAH |
| Glimepiride Canon glimepiride | 50 rub | -- |
| Glimepiride Pharmacyard glimepiride | -- | -- |
| Dimaril glimepiride | -- | 21 UAH |
| Glamepiride diamerid | 2 rub | -- |
| Amaryl M Limepiride Micronized, Metformin Hydrochloride | 856 rub | 40 UAH |
| Glibomet glibenclamide, metformin | 257 rub | 101 UAH |
| Glucovans glibenclamide, metformin | 34 rub | 8 UAH |
| Dianorm-m Glyclazide, Metformin | -- | 115 UAH |
| Dibizid-m glipizide, metformin | -- | 30 UAH |
| Douglimax glimepiride, metformin | -- | 44 UAH |
| Duotrol glibenclamide, metformin | -- | -- |
| Gluconorm | 45 rub | -- |
| Glibofor metformin hydrochloride, glibenclamide | -- | 16 UAH |
| Avandamet | -- | -- |
| Avandaglim | -- | -- |
| Janumet metformin, sitagliptin | 9 rub | 1 UAH |
| Velmetia metformin, sitagliptin | 6026 rub | -- |
| Galvus Met vildagliptin, metformin | 259 rub | 1195 UAH |
| Tripride glimepiride, metformin, pioglitazone | -- | 83 UAH |
| Comboglize XR metformin, saxagliptin | -- | 424 UAH |
| Comboglyz Prolong metformin, saxagliptin | 130 rub | -- |
| Gentadueto linagliptin, metformin | -- | -- |
| Vipdomet metformin, alogliptin | 55 rub | 1750 UAH |
| Sinjardi empagliflozin, metformin hydrochloride | 240 rub | -- |
| Voglibose Oxide | -- | 21 UAH |
| Glutazone pioglitazone | -- | 66 UAH |
| Dropia Sanovel pioglitazone | -- | -- |
| Januvia sitagliptin | 1369 rub | 277 UAH |
| Galvus vildagliptin | 245 rub | 895 UAH |
| Onglisa saxagliptin | 1472 rub | 48 UAH |
| Nesina alogliptin | -- | -- |
| Vipidia alogliptin | 350 rub | 1250 UAH |
| Trazhenta linagliptin | 89 rub | 1434 UAH |
| Lixumia lixisenatide | -- | 2498 UAH |
| Sebaka sa Guarem Guar | 9950 rub | 24 UAH |
| Insvada repaglinide | -- | -- |
| Novonorm Repaglinide | 30 rub | 90 UAH |
| Repodiab Repaglinide | -- | -- |
| Baeta Exenatide | 150 rub | 4600 UAH |
| Baeta Long Exenatide | 10248 rub | -- |
| Viktoza liraglutide | 8823 rub | 2900 UAH |
| Saxenda liraglutide | 1374 rub | 13773 UAH |
| Forksiga Dapagliflozin | -- | 18 UAH |
| Forsiga Dapagliflozin | 12 rub | 3200 UAH |
| Invocana canagliflozin | 13 rub | 3200 UAH |
| Jardins Empagliflozin | 222 rub | 566 UAH |
| Trulicity Dulaglutide | 115 rub | -- |
U ka fumana analogue e theko e tlaase ea moriana o theko e phahameng?
Ho fumana analogue e theko e phahameng ea moriana, mofuta oa generic kapa lebitso, pele ho tsohle re khothaletsa ho ela hloko sebopeho, e leng lintho le lipontšo tse tšoanang tse sebetsang. Metsoako e tšoanang ea lithethefatsi e tla bonts'a hore lithethefatsi li tsamaisana le lithethefatsi, li ka lekana meriana kapa li ka etsa meriana. Leha ho le joalo, u se ke oa lebala ka likarolo tse sa sebetseng tsa lithethefatsi tse tšoanang, tse ka amang polokeho le ts'ebetso. Se ke la lebala ka litaelo tsa lingaka, ho itlama ho ka lematsa bophelo ba hau, ka hona, etela ngaka ea hau kamehla pele u sebelisa meriana leha e le efe.
Taelo ea Metfogamma
METFOGAMMA® (METFOGAMMA) Moemeli oa metformin: WERVAG FARMA GmbH le Co.KG li-pcs tse 10. - lithutsoana (12) - lipakete tsa karete.
Lipilisi, tse bosoeu-ba bosoeu ba lifilimi, tse nang le mola oa ho robeha.
1 tab metformin hydrochloride 850 mg
Baeti: methylhydroxypropyl cellulose, povidone, magnesium stearate, titanium dioxide (E171), macrogol 6000.
Li-pcs tse 10 - Liphutheloana tsa lithutsoana (3) - lipakete tsa karete. Li-pcs tse 10 - Marang-rang a lithutsoana (12) - lipakete tsa karete.
Ngoliso:
- tab. koaetso ea lifilimi, 850 mg: li-pcs tse 30 kapa tse 120. - P. 013816 / 01-2002, 03/12/02
- tab. ho koahela filimi, 500 mg: 30 kapa li-PC. - P No. 014463 / 01-2002, 10.16.02
Setlhare sa molomo sa hypoglycemic se tsoang sehlopheng sa Biguanide. E thibela gluconeogeneis ka har'a sebete, e fokotsa ho monya ha tsoekere ka mpeng, e ntlafatsa ts'ebeliso ea tsoekere, hape e eketsa kutloisiso ea lisele tsa mmele ho insulin. Ha e ame secretion ea insulin ke lisele tsa β-pancreas.
Lowers triglycerides, LDL.
E tsitsisa kapa e theola boima ba 'mele.
E na le phello ea fibrinolytic ka lebaka la khatello ea inhibitor ea tisy ea plasminogen activator.
Kamora ho tsamaisoa ka molomo, metformin e nkuoa ho tsoa mokokotlong oa lijo. Bioavailability kamora ho nka tekanyetso e tloaelehileng ke 50-60%. Cmax kamora ho tsamaisoa ka molomo e fihlelloa kamora lihora tse peli.
Ha e lumellane le liprotheine tsa plasma. E bokellana ka har'a litšoelesa tse qhekellang, mesifa, sebete le liphio.
E tšolotsoe e sa fetoha moroto. T1 / 2 ke lihora tse 1.5-4,5.
Pharmacokinetics maemong a khethehileng a kliniki
Ka ts'ebetso ea renal e sa sebetseng hantle, ho sebelisoa hoa lithethefatsi hoa khoneha.
- Type 2 lefu la tsoekere mellitus (e sa itšetlehang ka insulin) ntle le tloaelo ea ketoacidosis (haholoholo ho bakuli ba nang le botenya) ka kalafo ea phepo e sa sebetseng.
MOSOTHO DOSAGE
Beha ka bomong, o ela hloko boemo ba glucose maling.
Tekanyetso ea pele ea letsatsi le letsatsi hangata ke 0.5-1 g (Metfogamma 500) kapa 850 mg (Metfogamma 850). Keketseho e ntseng e eketseha butle-butle ea tekanyetso e ka khonahala ho latela phello ea kalafo. Tekanyetso ea tlhokomelo ea letsatsi le letsatsi e etsa 1-2 g (Metfogamm 500) kapa 0.85-1.7 g (Metfogamma 850). Tekanyetso e kholo ea letsatsi le letsatsi ke 3 g (Metfogamm 500) kapa 1.7 g (Metfogamma 850). Morero oa sethethefatsi ka tekanyetso e phahameng ha se eketse phello ea pheko.
Tekanyetso ea letsatsi le letsatsi e fetang 850 mg e khothaletsoa ho tekanyetso tse peli (hoseng le mantsiboea).
Bakeng sa bakuli ba tsofetseng, tekanyo e khothalletsoang ha ea lokela ho feta 850 mg / ka letsatsi.
Matlapa a lokela ho nooa le lijo ka kakaretso, a hlatsoe ka metsi a fokolang (khalase ea metsi).
Setlhare sena se reretsoe tšebeliso ea nako e telele.
PUSELETSO MAHALA
Ho tsoa ho ts'ebetso ea lijo: ho nyekeloa, ho hlatsa, ho opeloa ke mpa, lets'ollo, ho hloka takatso ea lijo, ho hloka takatso ea lijo, tatso ea tšepe molomong (joalo ka molao, ho khaotsa kalafo ha ho hlokehe, 'me matšoao a nyamela a le mong ntle le ho fetola tekanyetso ea moriana). Khafetsa le ho teba ha litlamorao ho ka fokotsoa ka keketseho ea butle-butle ea tekanyetso ea metformin.
Ho tsoa ho sistimi ea endocrine: hypoglycemia (ha e sebelisoa ka tekanyetso e sa lekanang).
Ho tloha lehlakoreng la metabolism: maemong a sa tloaelehang - lactic acidosis (e hloka ho khaoloa ha kalafo), ka tšebeliso ea nako e telele - B12 hypovitaminosis (malabsorption).
Ho tsoa ho sistimi ea hemopoietic: maemong a mang - anemia ea megaloblastic.
Litla-morao:
TLHOKOMELISO
- lefu la tsoekere ketoacidosis, lefu la tsoekere, leta,
- Ho senyeha ha renal,
- pelo le ho hloleha ho phefumoloha,
- karolo e mpe ea infarction ea myocardial,
- kotsi e mpe ea methapo ea methapo,
- joala bo sa foleng le maemo a mang a ka kenyang kholisong ea lactic acidosis,
- lactic acidosis le nalane ea eona,
- ho anyesa (matsoele),
- Hypersensitivity ho lithethefatsi.
Bokhachane le pelehi
Setlhare sena se kopantsoe hore se sebelisoe nakong ea kemaro le nakong ea keketseho (letsoele).
TLHOKOMELISO LITLHAKISO
Ts'ebeliso ea moriana ona ha e khothaletsoe mafu a tšoaetsanoang a hlobaetsang, ho mpefatsa maloetse a tšoaetsanoang a tšoaetsanoang le a tšoaetsanoang, likotsi, maloetse a opang ka matla, ha ho bontšoa kalafo ea insulin.
Setlhare ha se nkoe pele ho ts'ebetso ea bongaka le nakong ea matsatsi a mabeli kamora hore ba buuoe.
Ts'ebeliso ea Metfogamma ha e khothaletsoe bonyane matsatsi a 2 pele le matsatsi a 2 kamora x-ray kapa tlhatlhobo ea radiology a sebelisa liakhente tse fapaneng.
Ts'ebeliso ea lithethefatsi ha e khothalletsoe bakuli ho ja lijo tse nang le lithibelo ho kenella ka caloric (ka tlase ho 1000 kcal / ka letsatsi).
Ha ho khothalletsoe ho sebelisa lithethefatsi ho batho ba lilemo tse fetang 60 ba etsang mosebetsi o boima oa 'mele (hobane sena se amana le kotsi e eketsehang ea lactic acidosis).
Nakong ea ts'ebeliso ea lithethefatsi, matšoao a ts'ebetso ea renal a lokela ho hlahlojoa. Bonyane makhetlo a mabeli ka selemo, hammoho le ponahalo ea myalgia, litaba tsa lactate tse ho plasma li lokela ho ikemisoa.
Metfogamma e ka sebelisoa hammoho le lintho tse tsoang ho sulfonylurea kapa insulin, 'me ho hlokahala leihlo le hlokolosi la maemo a tsoekere ea mali.
PUSELETSO
Matšoao: lefu le lactic acidosis le ka hlaha. Sesosa sa nts'etsopele ea lactic acidosis le eona e ka ba ho lutla ha moriana ka lebaka la ts'ebetso ea renal e sa sebetseng. Matšoao a pele a lactic acidosis ke ho nyekeloa pelo, ho hlatsa, lets'ollo, ho fokotsa mocheso oa 'mele, bohloko ba ka mpeng, bohloko ba mesifa, nakong e tlang ho kanna ha eba le ho hema ho eketsehileng, ho tsekela, ho hloka kelello le ho holofala.
Phekolo: haeba ho na le matšoao a lactic acidosis, kalafo e nang le Metfogamma e lokela ho emisoa hang-hang, mokuli o lokela ho kena sepetlele ka potlako mme ha a se a lemohile hore o na le lactate, netefatsa tlhahlobo eo. Hemodialysis e sebetsa hantle haholo bakeng sa ho tlosa lactate le metformin 'meleng. Haeba ho hlokahala, etsa kalafo e nang le matšoao. Ka kalafo e kopaneng le sulfonylureas, hypoglycemia e ka hlaha.
TLHOKOMELISO LITLHAKISO
Ka ts'ebeliso e le 'ngoe le metsoako ea sulfonylurea, acarbose, insulin, NSAIDs, li-inhibitors tsa MAO, oxetetracycline, li-inhibitors tsa ACE, clofibrate, cyclophosphamide, beta-blockers, ho khonahala ho eketsa phello ea hypoglycemic ea metformin.
Ka ts'ebeliso e le 'ngoe le GCS, lithibela-pelehi tsa molomo, epinephrine (adrenaline), sympathomimetics, glucagon, lihomone tsa qoqotho, thiazide le loopback diuretics, melemo ea phenothiazine, li-nicotinic acid tse tlisoang, ho fokotseha hoa phello ea hypoglycemic ea metformin hoa khoneha.
Cimetidine e liehisa ho felisoa ha metformin, e eketsang kotsi ea lactic acidosis.
Metformin e ka fokolisa phello ea li-anticoagulants (tse tsoang ho coumarin).
Ka tsamaiso e ts'oanang ka ethanol, nts'etsopele ea lactic acidosis e khonahala.
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Lefu la 2 la lefu la tsoekere
Chromium bakeng sa tahlehelo ea boima ba 'mele le kalafo ea lefu la tsoekere la mofuta oa 2. ... -
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