Eslidine (Eslidine)

Lintho tse sebetsang -methionine le phospholipids. Setlhare se tloaelehileng sa metabolism: lik'habohaedreite, mafura le protheine. Ntho e sebetsang ke amino acid ea bohlokoa (mohloli oa lihlopha tsa mobile tsa methyl).

Methionine e thibela ho kenngoa ha mafura a sa nke lehlakore ka har'a sebete, ho matlafatsa motsoako phospholipids ea endo native mme e nka karolo mohato oa ho kopanya choline. Ka atherosclerosis, methionine e eketsa boemo ba phospholipids le ho fokotsa khatello ea cholesterol, e lebisang ho fokotseha ha palo ea cholesterol plaque.

Lithako tse sebetsang li inactivate xenobiotice kenya letsoho lits'ebetsong tsa metabolic tsa li-amino acid tse nang le sebabole, ka har'a syntheineine, epinephrine le lintho tse ling tse sebetsang.

Methionine e ameha ho li-decarboxylation, deamination, transmethylation reaction, e fetola ketso ea liprotheine, li-enzyme, livithamini (li-folic le ascorbic acid, cyanocobalamin) le lihormone.

Phospholipids tsa bohlokoake lintlha tsa tlatsetso kholisong le tšebetsong ea lisele tsa sebete. Karolo e ka sehloohong ea phospholipids e emeloa phosphatidylcholine (Karolo e kholo ea sebopeho sa membranes). Tlas'a tšusumetso ea phosphatidylcholine, tšebetso ea maqhubu a lisele tsa sebete e matlafatsoa, ​​'me ho ts'epahala le ho ts'epahala ha litho tsa lisele tse senyehileng tsa sebete.

Li-phospholipids tsa bohlokoa le methionine li na le phello e matla ea hepatoprotective, li ntlafatsa sebopeho se sebetsang sa sebete, ke mohloli oa phospholipids (exo native and endo native), mme e ka ba le phello ea e mong le e mong.

Matšoao a ho sebelisoa

Ts'ebetsong ea gastroenterological, ho laetsoe moriana oa meriana hepatitis (a hlobaetsang, a sa foleng a sa foleng, ntle le vaerase hepatitis), lefu la sebete, lefu la mafura, tšenyo e chefo (lithethefatsi, lithethefatsi, joala), le ts'ebetso ea hepatocyte e holofetseng (hangata e ba phepelo ea lefu le ka tlase) hepatobiliary system.

Litaelo tsa ho sebelisoa ha Eslidine li khothaletsa ho fana ka moriana e le karolo ea kalafo e rarahaneng ea psoriasis. Ka lefu la pelo, moriana o laetsoe atherosclerosis ho fokotsa molumo cholesterol plaques, ho fokotsa boima ba litla-morao ha u nka li-statins.

Li-capslines tsa Eslidine li reretsoe ts'ebetso ea dystrophic, khaello e mpe ea phepo e nepahetseng le lefu la tsoekere hammoho le meriana ea mantlha.

Contraindication

Eslidin ea lithethefatsi ha e fuoe tšoaetso ea lefu la sebete, lefu le matla la tsamaiso ea sebete (kotsi e kholo ea ho eketseha hyperazotemia), ka mamello ea methionine, le hepatic encephalopathy. Moriana o ka sebelisoa liketsong tsa bana ho tloha ho lilemo tse 3.

Nakong ea kemolo, matlapa a Eslidine a laetsoe ka hloko, ho buisana le boto ea bongaka hoa hlokahala.

Lik'hasete tsa Eslidine, Litaelo tsa Ts'ebeliso (Mokhoa le Tekanyetso)

Nka ka molomo ka metsi. Ho molemo ho ja le lijo.

Pathology ea tsamaiso ea sebete, mokhathala, dystrophy,cerebral arteriosulinosislefu la tsoekere: likhahla tse peli makhetlo a mararo ka letsatsi. Tlhahlobo e fokolang ea kalafo ke khoeli e le 1, e khothalletsoang ke likhoeli tse 3.

Phekolo e phethahetseng ea psoriasis: Li-capsules tse tharo makhetlo a mararo ka letsatsi bakeng sa libeke tse peli.

Bana ba lilemo tse 7 le mafura a senyehileng, lefu la tsoekere, lefu la sebete le khetha makhetlo a mabeli ka makhetlo a 3 ka letsatsi, thupelo e etselitsoe likhoeli tse 1-3. Bana ba lilemo li 3-7, tekanyetso e le 'ngoe e fokotseha ho 1 capsule.

Tlhophiso ea Nosological (ICD-10)

Likapole1 likhahla.
Lintho tse sebetsang:
phospholipids (Lipoid PPL-400)300 mg
(mabapi le dikahare tsa 100% tsa phospholipids tsa polyunsaturated tse tsoang soya lecithin - karolo ea PPL)
methionine100 mg
soya oli ea linaoa - ho fihlela ho 550 mg
sebopeho sa khalase ea gelatin e thata ('mele le cap): titanium dioxide, dae iron oxide e ntšo, dae e nang le oxide e khubelu, dae ea oxide e tshehla, metsi, gelatin

Sokolla foromo le sebopeho

Mofuta oa litekanyetso tsa tokollo ke li-capsules: gelatin e thata, 'mele o sootho, sootho se sootho, saese. 0, likhabapo li na le' mala o sootho / sootho ho tloha ho buttery ho ea tumellanong ea denser, e nang le monko o nang le tšusumetso (10 kapa 15 ka contour liphutheloana tsa lisele, ka lebokoseng la mekotla ea 2-6, 9 kapa 10, li-pcs tse 30, 50, 60 kapa 100. ka likhalase tsa khalase / tsa polasetiki, ka lebokoseng la mekotla ea 1 e ka ba).

Lintho tse sebetsang tse kahare ea 1

  • PPL-400 lipoid (li-phospholipids tsa polyunsaturated tse tsoang soya lecithin) - 300 mg,
  • methionine - 100 mg.

  • Litaba tsa capule: oli ea soya - ho fihlela ho 550 mg,
  • capsule shell: titanium dioxide, e ntšo, e khubelu le e tshehla oxide oxide, gelatin, metsi a hloekisitsoeng.

Litaelo tsa ts'ebeliso ea Eslidine: mokhoa le litekanyetso

Eslidine e nooa ka molomo, haholo-holo ka lijo. Li-capsules li metsoa kaofela ka metsi a lekaneng.

Tekanyetso e khothalelitsoeng e le 'ngoe (e nang le khafetsa ea tsamaiso makhetlo a 3 ka letsatsi):

  • bana ba lilemo li 7 ho ea ho ba baholo: li-capsules tse 2,
  • bana ba lilemo tse 3 - 7: sekhechana se le seng.

Nako ea karolelano ea karolelano:

  • lefu la sebete, lefu la methapo ea methapo ea methapo ea kutlo le methapo ea mali ea bokong, lefu la tsoekere, lefu la methapo ea kutlo le mokhathala: likhoeli tse 1-3,
  • psoriasis: libeke tse 2.

Litlamorao

Likarabo tsohle li tlalehiloe e le 'ngoe.

Lik'hasete tsa Eslidine, Litaelo tsa Ts'ebeliso (Mokhoa le Tekanyetso)

Nka ka molomo ka metsi. Ho molemo ho ja le lijo.

Pathology ea tsamaiso ea sebete, mokhathala, dystrophy,cerebral arteriosulinosislefu la tsoekere: likhahla tse peli makhetlo a mararo ka letsatsi. Tlhahlobo e fokolang ea kalafo ke khoeli e le 1, e khothalletsoang ke likhoeli tse 3.

Phekolo e phethahetseng ea psoriasis: Li-capsules tse tharo makhetlo a mararo ka letsatsi bakeng sa libeke tse peli.

Bana ba lilemo tse 7 le mafura a senyehileng, lefu la tsoekere, lefu la sebete le khetha makhetlo a mabeli ka makhetlo a 3 ka letsatsi, thupelo e etselitsoe likhoeli tse 1-3. Bana ba lilemo li 3-7, tekanyetso e le 'ngoe e fokotseha ho 1 capsule.

Bongata

Ho ka fokotseha ha khatello ea mali, tachycardia, disoriation.

Phekolo ke letšoao.

Tšebelisano

Litšebelisano tsa bohlokoa tsa pharmacological ha li hlalosoe.

Lipehelo tsa thekiso

O ka reka Eslidin ka har'a marang-rang a meriana ha u hlahisa lengolo la ngaka.

Maemo a polokelo

Li-capsule li tlameha ho bolokoa sebakeng se lefifi. Mocheso o khothalelitsoeng + 25 degrees Celsius.

Analogs of Eslidine

Slash, Phosphogliv, Heptral, Essentiale (tatellano ho latela matšoao a bongaka, empa eseng ka sebopeho).

Theko ea li-analogu ka kakaretso e phahame haholo.

Litlhahlobo mabapi le Eslidine

Litlhahlobo mabapi le Eslidine liforong li bonts'a mamello e ntle ho lithethefatsi.

Moriana o hlile oa thusa, o ntlafatsa boemo ba sebete, liteko le bophelo bo botle ka kakaretso.

Theko Eslidina moo u ka rekang teng

Theko ea Eslidin ke li-ruble tse 580 bakeng sa likhaba tse 30.

Sokolla foromo le sebopeho

Mofuta oa litekanyetso tsa tokollo ke li-capsules: gelatin e thata, 'mele o sootho, sootho se sootho, saese. 0, likhabapo li na le' mala o sootho / sootho ho tloha ho buttery ho ea tumellanong ea denser, e nang le monko o nang le tšusumetso (10 kapa 15 ka contour liphutheloana tsa lisele, ka lebokoseng la mekotla ea 2-6, 9 kapa 10, li-pcs tse 30, 50, 60 kapa 100. ka likhalase tsa khalase / tsa polasetiki, ka lebokoseng la mekotla ea 1 e ka ba).

Lintho tse sebetsang tse kahare ea 1

  • PPL-400 lipoid (li-phospholipids tsa polyunsaturated tse tsoang soya lecithin) - 300 mg,
  • methionine - 100 mg.

  • Litaba tsa capule: oli ea soya - ho fihlela ho 550 mg,
  • capsule shell: titanium dioxide, e ntšo, e khubelu le e tshehla oxide oxide, gelatin, metsi a hloekisitsoeng.

Melemo ea pharmacological

Pharadodynamics

Eslidine ke e 'ngoe ea lithethefatsi tse kopaneng le ts'ebetso ea hepatoprotective, e tloaelehileng mefuta eohle ea metabolism (protheine, mafura, carbohydrate).

  • methionine: amino acid ea bohlokoa eo e leng mohloli oa lihlopha tsa methyl ea mobile. Hoa hlokahala bakeng sa ho se sebetse ha xenobiotic, motsoako oa choline. Keketseho ea litaba tsa eona e lebisa keketseho ea motsoako oa phospholipids ea kahare (endo native) le phokotseho ea ho hlahisoa ha mafura a se nang lehlakore ka har'a sebete. Ho bakuli ba atherosclerosis, e eketsa bongata ba mali phospholipids mme e fokotsa khatello ea cholesterol. Methionine e nka karolo phapanyetsanong ea li-amino acid tse tsoekere, ka har'a motsoako oa creatinine, epinephrine le metsoako e meng e sebetsang ea phetoho, e fetolang ketso ea liprotheine, lihormone, li-enzyme, livithamini (B12, folic le ascorbic acid), e ameha ho decarboxylation, deamination, remethylation reaction,
  • phospholipids tsa bohlokoa: lintlha tsa bohlokoahali tse hlokahalang bakeng sa nts'etsopele le tšebetso ea lisele tsa sebete. Karolo ea bona ea sehlooho e emeloa ke phosphatidylcholine (73%). Ke karolo ea bohlokoa ea li-membrane tsa likokoana-hloko. Ha phosphatidylcholine e kena 'meleng, e thusa ho khutlisetsa botsitso ba litho tsa lisele tse amehang tsa sebete, hape e kenya tšebetsong li-enzyme tse itšetlehileng ka phospholipid tse fumanehang kahara membrane, ha boteng ba matla a lisele tsa sebete le bona bo ntlafatsoa.

Lintho tse sebetsang li ntlafatsa phello ea e 'ngoe, ka lebaka leo maemo a sebetsang a lisele tsa sebete a ntlafatsang.

Eslidine e thusa ho khutlisetsa ts'ebetso ea sebete, e eketsa bokhoni ba eona ba ho tsamaisa 'mele, hammoho le ho monya mafura, protheine le metabolism ea' mele 'meleng.

Matšoao a ho sebelisoa

Eslidine e laetsoe ho dermatology, gastroenterology, cardiology le neurology moo ho nang le matšoao a latelang:

  • Tšenyo ea sebete e nang le chefo (narcotic, lino tse tahang, setlhare),
  • mafura a sebete a mefuta e fapa-fapaneng,
  • cirrhosis ea sebete
  • chronic / hepatitis e hlobaetsang (ntle le vaerase),
  • ho senyeha hoa hepatocytes (ka mathata a bakoang ke mafu a mang),
  • dystrophy, mokhathala,
  • pele ho nako le ts'ebetso ea ts'ebetso le ho kenella kahare ho sebaka sa hepatobiliary,
  • psoriasis (ka nako e tšoanang le lithethefatsi tse ling),
  • cerebral arteriosulinosis (ka nako e tšoanang le lithethefatsi tse ling),
  • lefu la tsoekere (hammoho le meriana e meng),
  • atherosulinosis ea methapo ea kutlo (ka nako e tšoanang le lithethefatsi tse ling).

Contraindication

  • vaerase ea lefu la sebete
  • ho hloleha ho matla ha sebete, hepatic encephalopathy,
  • lilemo ho isa ho lilemo tse 3
  • hypersensitivity ho likarolo tsa moriana.

Setsoalle (Eslidine e beoa tlasa tataiso ea bongaka):

  • ho ima le ho nyekeloa,
  • lilemo tse 3-7
  • ho hloleha ha rems.

Litaelo tsa ts'ebeliso ea Eslidine: mokhoa le litekanyetso

Eslidine e nooa ka molomo, haholo-holo ka lijo. Li-capsules li metsoa kaofela ka metsi a lekaneng.

Tekanyetso e khothalelitsoeng e le 'ngoe (e nang le khafetsa ea tsamaiso makhetlo a 3 ka letsatsi):

  • bana ba lilemo li 7 ho ea ho ba baholo: li-capsules tse 2,
  • bana ba lilemo tse 3 - 7: sekhechana se le seng.

Nako ea karolelano ea karolelano:

  • lefu la sebete, lefu la methapo ea methapo ea methapo ea kutlo le methapo ea mali ea bokong, lefu la tsoekere, lefu la methapo ea kutlo le mokhathala: likhoeli tse 1-3,
  • psoriasis: libeke tse 2.

Litlamorao

Litla-morao li ka ba mathata.

Bongata

Matšoao a ka sehloohong: ho fokotseha ha khatello ea mali, ho ferekana kelellong, ho eketseha ha pelo.

Litlhahlobo mabapi le Eslidine

Litlhahlobo mabapi le Eslidine liforong li bonts'a mamello e ntle ho lithethefatsi.

Moriana o hlile oa thusa, o ntlafatsa boemo ba sebete, liteko le bophelo bo botle ka kakaretso.

Theko Eslidina moo u ka rekang teng

Theko ea Eslidin ke li-ruble tse 580 bakeng sa likhaba tse 30.

Sokolla foromo le sebopeho

Mofuta oa litekanyetso tsa tokollo ke li-capsules: gelatin e thata, 'mele o sootho, sootho se sootho, saese. 0, likhabapo li na le' mala o sootho / sootho ho tloha ho buttery ho ea tumellanong ea denser, e nang le monko o nang le tšusumetso (10 kapa 15 ka contour liphutheloana tsa lisele, ka lebokoseng la mekotla ea 2-6, 9 kapa 10, li-pcs tse 30, 50, 60 kapa 100. ka likhalase tsa khalase / tsa polasetiki, ka lebokoseng la mekotla ea 1 e ka ba).

Lintho tse sebetsang tse kahare ea 1

  • PPL-400 lipoid (li-phospholipids tsa polyunsaturated tse tsoang soya lecithin) - 300 mg,
  • methionine - 100 mg.

  • Litaba tsa capule: oli ea soya - ho fihlela ho 550 mg,
  • capsule shell: titanium dioxide, e ntšo, e khubelu le e tshehla oxide oxide, gelatin, metsi a hloekisitsoeng.

Melemo ea pharmacological

Pharadodynamics

Eslidine ke e 'ngoe ea lithethefatsi tse kopaneng le ts'ebetso ea hepatoprotective, e tloaelehileng mefuta eohle ea metabolism (protheine, mafura, carbohydrate).

  • methionine: amino acid ea bohlokoa eo e leng mohloli oa lihlopha tsa methyl ea mobile. Hoa hlokahala bakeng sa ho se sebetse ha xenobiotic, motsoako oa choline. Keketseho ea litaba tsa eona e lebisa keketseho ea motsoako oa phospholipids ea kahare (endo native) le phokotseho ea ho hlahisoa ha mafura a se nang lehlakore ka har'a sebete. Ho bakuli ba atherosclerosis, e eketsa bongata ba mali phospholipids mme e fokotsa khatello ea cholesterol. Methionine e nka karolo phapanyetsanong ea li-amino acid tse tsoekere, ka har'a motsoako oa creatinine, epinephrine le metsoako e meng e sebetsang ea phetoho, e fetolang ketso ea liprotheine, lihormone, li-enzyme, livithamini (B12, folic le ascorbic acid), e ameha ho decarboxylation, deamination, remethylation reaction,
  • phospholipids tsa bohlokoa: lintlha tsa bohlokoahali tse hlokahalang bakeng sa nts'etsopele le tšebetso ea lisele tsa sebete. Karolo ea bona ea sehlooho e emeloa ke phosphatidylcholine (73%). Ke karolo ea bohlokoa ea li-membrane tsa likokoana-hloko. Ha phosphatidylcholine e kena 'meleng, e thusa ho khutlisetsa botsitso ba litho tsa lisele tse amehang tsa sebete, hape e kenya tšebetsong li-enzyme tse itšetlehileng ka phospholipid tse fumanehang kahara membrane, ha boteng ba matla a lisele tsa sebete le bona bo ntlafatsoa.

Lintho tse sebetsang li ntlafatsa phello ea e 'ngoe, ka lebaka leo maemo a sebetsang a lisele tsa sebete a ntlafatsang.

Eslidine e thusa ho khutlisetsa ts'ebetso ea sebete, e eketsa bokhoni ba eona ba ho tsamaisa 'mele, hammoho le ho monya mafura, protheine le metabolism ea' mele 'meleng.

Matšoao a ho sebelisoa

Eslidine e laetsoe ho dermatology, gastroenterology, cardiology le neurology moo ho nang le matšoao a latelang:

  • Tšenyo ea sebete e nang le chefo (narcotic, lino tse tahang, setlhare),
  • mafura a sebete a mefuta e fapa-fapaneng,
  • cirrhosis ea sebete
  • chronic / hepatitis e hlobaetsang (ntle le vaerase),
  • ho senyeha hoa hepatocytes (ka mathata a bakoang ke mafu a mang),
  • dystrophy, mokhathala,
  • pele ho nako le ts'ebetso ea ts'ebetso le ho kenella kahare ho sebaka sa hepatobiliary,
  • psoriasis (ka nako e tšoanang le lithethefatsi tse ling),
  • cerebral arteriosulinosis (ka nako e tšoanang le lithethefatsi tse ling),
  • lefu la tsoekere (hammoho le meriana e meng),
  • atherosulinosis ea methapo ea kutlo (ka nako e tšoanang le lithethefatsi tse ling).

Contraindication

  • vaerase ea lefu la sebete
  • ho hloleha ho matla ha sebete, hepatic encephalopathy,
  • lilemo ho isa ho lilemo tse 3
  • hypersensitivity ho likarolo tsa moriana.

Setsoalle (Eslidine e beoa tlasa tataiso ea bongaka):

  • ho ima le ho nyekeloa,
  • lilemo tse 3-7
  • ho hloleha ha rems.

Litaelo tsa ts'ebeliso ea Eslidine: mokhoa le litekanyetso

Eslidine e nooa ka molomo, haholo-holo ka lijo. Li-capsules li metsoa kaofela ka metsi a lekaneng.

Tekanyetso e khothalelitsoeng e le 'ngoe (e nang le khafetsa ea tsamaiso makhetlo a 3 ka letsatsi):

  • bana ba lilemo li 7 ho ea ho ba baholo: li-capsules tse 2,
  • bana ba lilemo tse 3 - 7: sekhechana se le seng.

Nako ea karolelano ea karolelano:

  • lefu la sebete, lefu la methapo ea methapo ea methapo ea kutlo le methapo ea mali ea bokong, lefu la tsoekere, lefu la methapo ea kutlo le mokhathala: likhoeli tse 1-3,
  • psoriasis: libeke tse 2.

Litlamorao

Litla-morao li ka ba mathata.

Bongata

Matšoao a ka sehloohong: ho fokotseha ha khatello ea mali, ho ferekana kelellong, ho eketseha ha pelo.

Bokhachane le pelehi

Ho ea ka litaelo, Eslidine ha e khethoe nakong ea kemolo / nakong ea ho anyesa.

Sebelisa bongoaneng

  • bana ba ka tlase ho lilemo tse 3: kalafo e hanyetsitsoe,
  • bana ba lilemo li 3-7: sethethefatsi se laetsoe ka hloko.

Ka mosebetsi o sa sebetseng oa renal

Kaha ho na le menyetla ea keketseho ea hyperazotemia, Eslidine ka ho se sebetse hantle ka mokhoa oa phepo e lokela ho sebelisoa ka hloko.

Ka ho se sebetse hantle ha sebete

Phekolo e kopantsoe le boteng ba lefu la sebete la sebete, ho hloleha ho matla ha sebete le ho ruruha ha methapo ea pelo.

Ho sebelisana le lithethefatsi

Ha ho na data mabapi le tšebelisano ea Eslidine le lithethefatsi tse ling / lintho tse ling.

Liratso tsa Eslidine ke: Resalut, Heptral, Phosphogliv, Essentiale.

Lipehelo le maemo a polokelo

Tsoa hole le bana ka mocheso ho fihlela 25 ° C.

Bophelo ba Shelf ke lilemo tse 2.

Lipehelo tsa Maemo a Phomolo ea meriana

E lokolloa ntle le lengolo la ngaka.

Litlhahlobo mabapi le Eslidine

Ho latela maikutlo, Eslidine ke sethethefatsi se theko e tlase ebile se sebetsang. E tsebahala ka mamello ea eona e ntle le ts'ebetso e potlakileng, e netefalitsoeng ke sephetho sa bohlahlobo.

Ketso ea pharmacological

Moriana o kopaneng o na le phello ea hepatoprotective, o etsa hore mefuta eohle ea metabolism (mafura, protheine, lik'habohaedreite).

Methionine, e leng e 'ngoe ea likarolo tse sebetsang tsa moriana, ke amino acid ea bohlokoa eo e leng mohloli oa lihlopha tsa methyl ea mobile. Methionine e hlokahala bakeng sa motsoako oa choline. Keketseho ea likateng tsa choline e eketsa tlhahiso ea li-phospholipids tsa endo native (ka hare) mme e fokotsa ho hlahisoa ha mafura a se nang lehlakore ka har'a sebete. Methionine e boetse e hlokahala bakeng sa ho se sebetse ha xenobiotic. Ka atherossteosis, e fokotsa khatello ea cholesterol le ho eketsa phallo ea phospholipids ea mali.

Phospholipids ea bohlokoa ke lintlha tsa bohlokoahali bakeng sa nts'etsopele le tšebetso ea lisele tsa sebete. Karolo e ka sehloohong ea li-phospholipids tsa bohlokoa tokisetsong e emeloa ke phosphatidylcholine (73%), e leng eona karolo ea mantlha ea li-membrane tsa likokoana-hloko. Hang ha e le 'meleng, phosphatidylcholine e khutlisetsa botsitso ba litho tsa lisele tse amehang tsa sebete mme e kenya tšebetsong li-enzyme tse itšetlehileng ka phospholipid tse fumanehang kahara membrane, ka tsela eo e fetole boemo ba eona le ho ntlafatsa detoxation le bokhoni bo botle ba lisele tsa sebete.

Methionine le li-phospholipids tsa bohlokoa li ntlafatsa ts'ebetso ea e mong, ho ba mohloli oa endo native (kahare) le kantle (ho kenella 'meleng) phospholipids, ka ho latellana, e ntlafatsa maemo a sebetsang a lisele tsa sebete mme o na le phello ea hepatoprotective (sireletsa).

Methionine e nka karolo phapanyetsanong ea li-amino acid tse sebabole, ka har'a motsoako oa epinephrine, creatinine le metsoako e meng e sebetsang ea phetoho ea limela, ho fetola ketso ea lihormone, livithamini (B 12, ascorbic acid, folic acid), li-enzyme, liprotheine, le ho nka karolo mekhoeng ea methylation, deamination, decarboxylation. Eslidine® e khutlisetsa ts'ebetso ea sebete, e ntlafatsa ho tsamaisoa ha eona

bokhoni, hape e boetse e tloaetse metabolism ea mafura, khabone le protheine 'meleng.

Bokhachane le pelehi

Boithuto bo netefatsang polokeho ea Eslidine® ea popelo le polokeho ea lesea nakong ea matsoele ha li so etsoa. Ts'ebeliso ea moriana nakong ea kemolo le ho lactation e ka etsahala feela joalo ka ha ho laetsoe ke ngaka maemong ao melemo e boletsoeng ho 'm'a e fetang kotsi e ka bang teng ho lesea le lesea.

Tekanyetso le tsamaiso

Setlhare se nooa ka molomo nakong ea lijo, sa metsa kaofela, ka metsi a lekaneng.

Bakeng sa mafu a sebete, atherosclerosis ea methapo ea methapo ea methapo le methapo ea methapo, lefu la tsoekere, lefu la tsoekere le mokhathala, nka makhetlo a mabeli makhetlo a 3 ka letsatsi. Tlhahlobo e khothalletsoang ea kalafo ke likhoeli tse 3, bonyane ke khoeli e le 'ngoe.

Ka psoriasis - likhabapo tse 2 makhetlo a 3 ka letsatsi. Tsela e khothalletsoang ea kalafo ke libeke tse peli.

Bana ba ka holimo ho lilemo tse 7 ba nang le mafu a sebete, lefu la tsoekere, lefu la mafura a mangata - makhetlo a 2 ka makhetlo a mararo ka letsatsi, bakeng sa likhoeli tse 1-3.

Ka psoriasis, bana ba ka holimo ho lilemo tse 7 - likhabapo tse 2 makhetlo a 3 ka letsatsi, bakeng sa libeke tse 2. Tšebeliso ea lithethefatsi ho bana ho tloha ho ba lilemo li 3 ho isa ho tse 7 - 1 capsule makhetlo a 3 ka letsatsi, bakeng sa likhoeli tse 1-3.

Likarolo tsa ts'ebeliso

Ka tlhokomeliso, hoa khoneha ho sebelisa nakong ea bokhachane le ho bana ho tloha ho lilemo tse 3 ho isa ho tse 7, hammoho le ho se sebetse hantle ha methapo (ka lebaka la kotsi ea kholo ea hyperazotemia).

Tlhahiso-leseling ea polokeho

Bofuma ba lithethefatsi Eslidin ®, li-capsules li ile tsa ithutoa Setsing sa Saense sa All-Russian bakeng sa Ts'ireletso ea Biologically Active Sub zinthu (VSC BAS) (Kupavna) tekong e matla le e fokolang ea subchronic. Boithuto ba chefo e matla ea Eslidine® e entsoe ka litoeba tse tona tse tšoeu tse sa sebetsoang ka mokhoa o sa laoloang ka litekanyetso tsa 3000, 5000 le 6000 mg / kg. Intoxication (phetoho e nyane mekhoeng ea boitšoaro, e bonts'itsoeng ka mokhoa oa ho phefumoloha ho eketsehileng, ho hlophisoa ha liphoofolo, ho fokotseha hoa ts'ebetso ea motor) ho litoeba tsa liteko tse ntlafalitsoeng nakong ea metsotso ea 30-40 ea pele, kamora moo boits'oaro bo botle bo ile ba khutlela bo tloaelehileng butle-butle. Ha ho lefu le ileng la bonoa. Ho latela sephetho sa ho khetholla chefo e matla ha e kenngoa ka mpeng ea mpa ea phoofolo, Eslidin® e khethiloe e le sehlopha sa boloi ba VI ho latela sehlopha sa K.K.

Sekhahla sa subtronic sa Eslidine® se ithutoe ka likhoto tse tšoeu tse 40 ka tšohanyetso tse nang le boima ba 206 ± 4. Likahare tsa likhapha li ne li fanoa e le tharollo ea metsi hang ka letsatsi intragastrically, bakeng sa khoeli e le ngoe ho litekanyetso tse 70 (kalafo) le 700 mg / kg, makhetlo a leshome ho feta kalafo ea kalafo bakeng sa likhoto le makhetlo a 70 bakeng sa batho.

Ho latela sephetho sa tlhahlobo ena, Eslidin® litekong tse ithutoang ha ea ka ea baka liphetoho tse kholo lithutong tsa bohlokoa liphoofolong tsa tlhahlobo (boima ba 'mele, boits'oaro ba boitšoaro, lijo, tšebeliso ea metsi), sebopeho sa cellular le li-paramente tsa pherekano ea mali, phello, ho amoheloa, ts'ebetso ea protheine, carbohydrate tšebetso ea sebete. , boemo ba k'holeseterole e serum ea mali, boemo bo sebetsang ba litsamaiso tsa pelo le methapo. Eslidine® e ne e se na phello e halefisang ea lehae.

Setlhare ho litekanyetso tse ithutoang ha sea ka sa baka mathata a sebopeho lithong le lithong. Tlas'a tšusumetso ea lithethefatsi ka tekanyo ea 700 mg / kg, li-follicles tse nang le litsi tse sebetsang hantle, karabelo e kholo ea macrophage e fumanoe methapong ea methapo, ho ata ha 'mele oa Gassal bokong ba bokong ba tšoelesa ea thymus, le ka har'a sebetele hona tšubuhlellano ea venous, ho kenella kahare ho lymphoid-hertiocytic, le hemstophy e bonolo ea hepatocyte ho ile ha hlokomeloa Berezovskaya, I. V., Rymartsev, V. I., Spassky, Yu. A. et al., 2004. Mutagenicity, carcinogenicity

Lithuto tsa in vitro tse nang le mefuta ea salmonella le tomoso, tse nang le mela ea lisele tsa motho, hammoho le lithutong tsa vivo ha lia ka tsa senola monyetla oa mutagenic oa phospholipids ea bohlokoa. Ho latela FDA (USA), le Setsi sa Kankere sa Jeremane, phospholipids ea bohlokoa ha se karolo ea sehlopha sa dintho tse nang le carcinogenicity Gaggi, R., Biagi, G. L., 1983.

Ha ho na bopaki ba carcinogenicity ea methionine. Chefo ea ho ikatisa, embryotoxicity, teratogenicity Ha ho na litlamorao tse chefo li ileng tsa bonoa ho basali ba baimana le masea a bona ka ho hlahisoa hoa li-phospholipids tsa bohlokoa ho tekanyetso ho fihlela ho 1000 mg / kg (likhoto) le 500 mg / kg (le mebutlanyana). Ho hlahisoa ha li-phospholipids tsa bohlokoa ka tekanyetso ho fihlela ho 3750 mg / kg ka molomo ha hoa ka ha ama nts'etsopele ea mantlha le kamora nako ea likhoto Leuschner F., 1972, Leuschner F., 1973, Sterner W., 1973, Sterner, W., Heiseler, E., 1970.

Ka tsamaiso ea molomo ea phospholipids ea bohlokoa ho litekanyetso tsa 150, 750 le 3750 mg / kg / letsatsi. tse tona (nakong ea libeke tse 10) le tse tšehali (libeke tse peli) tsa likhoto li ne li sa bonoeyaniya mabapi le bokhoni ba ho ba le bana le ho ba le bana Friehe N., Fontaine R., 1978.

Moetsi

Nizhpharm JSC, Russia. 603950, Nizhny Novgorod, st. Salgan, 7.

Mohala: (831) 278-80-88, fax: (831) 430-72-28.

kapa LLC MAKIZ-PHARMA, Russia. 109029, Moscow, Avtomobilny pr., 6, leq. 5.

Mohala: (495) 974-70-00, fekse: (495) 974-11-10

kapa Hemofarm LLC, Russia. 249030, Setereke sa Kaluga, Obninsk, Kievskoye sh., 62.

Mohala: (48439) 90-500, fekse: (48439) 90-525.

Lebitso le aterese ea mokhatlo oa molao eo lengolo la ngoliso / mokhatlo le amohelang likopo li fanoeng ka lebitso la hae. Nizhpharm JSC, Russia, 603950, Nizhny Novgorod, ul. Salgan, 7.

Mohala: (831) 278-80-88, fax: (831) 430-72-28.

Tekanyetso le nako ea kalafo

Tekanyo e nepahetseng le nako ea kalafo e khethoa ke ngaka e eang. Re fana ka mofuta oa kalafo o hakanyetsoang:

Lebitso la lefu lena

Boholo (li-capsules)

Nako le nako ea ho amoheloa (hang ka letsatsi)

Nako

Li-pathologies tsa lefu la sebete, atherosclerosis, lefu la tsoekere, lefu la tsoekere le mokhathala

Likhoeli tse 3, bonyane khoeli e le 'ngoe

Tekanyetso le litekanyetso tse kaholimo li sebelisoa ho batho ba baholo le bana ba fetang lilemo tse 7. Bana ba lilemo li 3 ho isa ho tse 7, ho khothalletsoa ho nka karolo e le 'ngoe ea "capsule" makhetlo a 3 ka letsatsi ka nako ea likhoeli tse 1-3.

Lipehelo le maemo a polokelo

Boloka sebakeng se lefifi 'me hole le bana. Nako ea ts'ebeliso Likhoeli tse 24.

Bophelo bo botle ba sebete bo lokela ho phekoloa ka hloko e kholo. Khafetsa, bohloko bo ka hara setho bo hlaha methating ea ho qetela ea lefu lena

Litsenyehelo tsa moriana li hakangoa li le holimo. Re fana ka lipalo tse hakanyetsoang:

Lithethefatsi islidine

Litšenyehelo Russia (rub.)

Litšenyehelo Ukraine (UAH)

Setlhare ha se na li-analogues tsa sebopeho, leha e na le li-phospholipids tse teng motheong oa li-hepatoprotectors tse ling tse ngata. Empa kaha e na le likarolo tse ling tse sebetsang, li-analogu tse joalo ha li tšoane ka sebopeho. Litlamorao tse tšoanang tsa kalafo li ka tsela e latelang:

Litlhahlobo mabapi le lithethefatsi li ntle haholo. Bareki ba ngola hore moriana o bonts'a katleho ea ona ka tekanyo e phahameng, o thusa ho sebetsana le mafu a fapaneng, ha o na litla-morao, ba eletsa moriana ona ho bakuli ba bang. Litlhaloso tse ntle li boetse li siiloe ke basali ba bakhachane mme ba ngola hore moriana o thusitse ho lokisa maemo a sebete le ho tlosa toxicosis, empa e tlameha ho nkuoa ka kotloloho ho latela taelo ea ngaka e eang.

Likotsi li kenyelletsa feela litšenyehelo tse phahameng tsa lithethefatsi, haholo-holo ka lithuto tse telele tsa kalafo.

Qeto

Nako e khutšoane mabapi le ts'ebeliso ea Eslidine:

  1. Eslidine ke sethethefatsi se kopaneng se tsoang sehlopheng sa meriana ea hepatoprotectors e tsoang Stada. E sebelisoa likarolong tse kang tsa bongaka tsa lefu la pelo, methapo ea kutlo, gastroenterology, dermatology, endocrinology.
  2. E fumaneha ka likhabapo. Sebopeho se na le likarolo tse sebetsang joalo ka amino acid methionine le phospholipids ea bohlokoa. Ntle le ketso e otlolohileng, ha e kopantsoe, lintho ka bobeli li ka ntlafatsa ketso ea e ngoe.
  3. Tekanyo e nepahetseng le nako ea thuto e khethoa ke ngaka feela. Mokhoa oa kalafo o hakanyetsoang oa batho ba baholo le bana o feta Lilemo tse 7 likhabapo tse peli makhetlo a mararo ka letsatsi ka mokhoa o fokolang oa phekolo ea khoeli e le 'ngoe le likhoeli tse tharo tse khothalelitsoeng (kalafo ea psoriasis matsatsi a 14). Nka moriana ka lijo, kahare.
  4. Moriana o lumelloa ho kalafo ea bana, ho qala ho tloha ho lilemo tse 3.
  5. E na le lithibelo ts'ebelisong ea kutloelo-bohloko e ikhethang ho sebopeho, hepatitis ea tlhaho ea vaerase, lefu le tebileng la sebete, ho haella ka matla le encephalopathy, lilemo ho isa ho lilemo tse 3.
  6. E sebelisoa ka hloko kalafo ea basali baimana, ba anyesang, ba lilemo li 3 ho isa ho tse 7, ba nang le bothata ba liphio.
  7. Litla-morao ke lipontšo tsa mzioa. Ho sebelisa joala ho feta tekano ho ka etsahala, maemong ana khatello ea mali ea phahama, sekhahla sa pelo sea potlaka, ho ferekana hoa hlaha.
  8. Maemo a polokelo a tloaelehile, nako ea lilemo tse 2, datha tsa ts'ebelisano ea lithethefatsi ha li fumanehe.
  9. Litsenyehelo tsa moriana li kaholimo ho karolelano. Bakeng sa li-capsules tse 30 tsa Russia u tlameha ho lefa 460-760 li-rubleUkraine 130-190 hryvnia.
  10. Eslidine ha e na li-analogues tsa sebopeho, empa e na le heptor, Ursoliv, Hofitol le tse ling tse tšoanang sehlopheng sa pharmacological.
  11. Maikutlo a bakuli a molemo haholo. Ba sekaseka phello ea kalafo, ho se be teng hoa litlamorao le ntlafatso ea maemo a akaretsang. Litlhaloso tse ntle li boetse li siiloe ke basali baimana, bao moriana o ileng oa thusa ho matlafatsa sebete le ho felisa toxicosis. Likotsi li kenyelletsa litšenyehelo tse phahameng.

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