Ciprolet meriana ea 500: matšoao, litla-morao le li-contraindication

Moriana "Tsiprolet 500" o bolela lithethefatsi tse thibelang likokoana-hloko mme o kenyelelitsoe sehlopheng sa fluoroquinolones. E etselitsoe phekolo ea li-pathologies tse sa foleng tsa ts'oaetso tse bakang microflora e amehang ka moriana. Sesebelisoa se na le ts'ebetso e phahameng le lebelo.

Phello ea kalafo ea kalafo "Tsiprolet 500"

Setlhare sena se kena-kenana le ho hlahisoa ha vaerase ea baktheria, ka tsela eo, se senya karohano ea bona le kholo ea bona. Moriana ona o sebetsa haholo bakeng sa kalafo ea maloetse a bakang baktheria e se nang gram (salmonella, E. coli, Klebsiella, Shigella). Moriana ona o ama le likokoana-hloko tse ntle tsa gram (streptococci, staphylococci). Sesebelisoa se sebelisoa ho phekola li-pathologies tse bakoang ke tšusumetso ea likokoana-hloko tse kenang kahare (chlamydia, tuberculous mycobacteria). Setlhare se boetse se sebetsa bakeng sa kalafo ea tšoaetso e bakoang ke Pseudomonas aeruginosa. Ciprolet 500 e hlahisoa ka mokhoa oa litafole tse nang le motsoako o sebetsang oa ligrama tse 0,5. Ho boetse ho na le lipilisi tse nang le bophahamo bo bonyenyane ba ntho ena (250 mg). Lokolla le tharollo ea infusion. Li-analogues tsa lithethefatsi ke Siflox, Ciprinol, Ciprofloxacin.

Matšoao a ho sebelisoa

Motsoana "Tsiprolet 500" o sebelisetsoa ho phekola tšoaetso ea tsebe, 'metso, nko, le mokhoa oa ho hema. Ts'ebeliso ea eona ho pneumonia e halefisitsoeng ke staphylococci, hemophilic bacilli, legionella, Klebsiella, enterobacter e bontšitsoe. Ka thuso ea sethethefatsi, ts'oaetso ea litho tsa mucous membrous, ducts ea bile, tsamaiso ea tšilo ea lijo, letlalo, mahlo, litho tse bonolo, litho tsa lefutso, ts'ehetso ea mesculoskeletal system, le li-pelvis tse nyane lia phekoloa. Nka lipilisi tsa sepsis, peritonitis, prostatitis, pelvioperitonitis, adnexitis.

Contraindication ea lithethefatsi "Tsiprolet 500"

Ho thibetsoe ho sebelisa meriana ena nakong ea kemolo, bana ba ka tlase ho lilemo tse ngata, bo-'mè ba anyesang, ba nang le hypersensitivity. Ba sebelisa moriana ka hloko maemong a ho potoloha hoa boko, ho se sebetse hantle ka mpeng, le sebete, bokuli ba kelello le lefu la sethoathoa. Ha ho ratehe ho fana ka pheko ho batho ba tsofetseng.

Litlamorao

Ha u sebelisa lithethefatsi, ho ka hlaha lintho tse mpe tse kang psychosis, diplopia, hallucinations, tinnitus, khatello ea maikutlo, mokhathala o eketsehileng oa intracranial, hlooho ea hlooho le ho hlobaela. Litho tsa ho ja li arabela tšebelisong ea matlapa a nang le lets'ollo, ho bata, ho felloa ke takatso ea lijo, ho hlatsa, bohloko ba ka mpeng le ho nyekeloa ke pelo. Nakong ea kalafo, hypotension, tachycardia, cholestatic jaundice, bohloko bo kopaneng le ba mesifa, ho makala ha anaphylactic, urticaria, bofubelu ba letlalo le ho hlohlona ho ka hlaha.

"Tsiprolet 500": litaelo tsa tšebeliso

Matlapa a nooa feela pele ho lijo, a hlatsuoa ka molora o moholo oa metsi. Tekanyo e itšetleha ka ho teba ha Psychology, lilemo tsa mokuli le boima ba 'mele oa hae. Bakeng sa kalafo ea lefu la makhopho, nka matlapa a 1 ayprolet (500 mg). Ho sebelisoa voliti e le 'ngoe bakeng sa ho phekola mafu a rarahaneng a methapo ea mokokotlo, prostatitis, mahlaba a basali, osteomyelitis, enterocolitis.

Sokolla foromo le sebopeho

Ciprolet e fumaneha ka mefuta e latelang ea litekanyetso:

Letlapa le koahetsoeng ka filimi: biconvex, pota, le sebaka se boreleli ka mahlakoreng a mabeli, hoo e batlang e le bosoeu kapa bosoeu, ho robeha hoo e batlang e le bosoeu kapa bosoeu (likotoana tse 10 ka lithutsoana, lilakane tse 1 kapa tse peli ka sekotong sa karete ea karete)
Tharollo ea infusion: mosehla o bobebe, o pepeneneng, o se nang 'mala (100 di ml ka ngoe ka botlolong ea polyethylene e fokolang haholo, botlolo e le 1 ka lebokoseng la karete)
Maqhubu a mahlo: a hlakileng, a mosehla o bobebe kapa o se nang 'mala (5 ml e' ngoe le e 'ngoe ka libotlolong tsa dropper, botlolo e le' ngoe ka lebokoseng la karete).

Moetso oa Letlapa le le leng o kenyelletsa:

Ntho e sebetsang: ciprofloxacin - 250 kapa 500 mg (ka tsela ea ciprofloxacin hydrochloride monohydrate - 291.106 kapa 582.211 mg, ka ho latellana),
Lintho tse thusang (250/500 mg, ka ho latellana): starch ea poone - 50.323 / 27,789 mg, cellcrystalline cellulose - 7.486 / 5 mg, talc - 5/6 mg, croscarmellose sodium - 10/20 mg, colloidal silicon dioxide - 5/5 mg, magnesium stearate - 3.514 / 4.5 mg,
Filimi sheath (250/500 mg, ka ho latellana): polysorbate 80 - 0,08 / 0,072 mg, hypromellose (6 cps) - 4,8 / 5 mg, titanium diode - 2 / 1,784 mg, sorbic acid - 0,08 / 0,072 mg Macrogol 6000 - 1.36 / 1.216 mg, talc - 1.6 / 1.784 mg, dimethicone - 0.08 / 0.072 mg.

Karolo ea 100 ml ea tharollo ea infusion e kenyelletsa:

Lintho tse sebetsang: ciprofloxacin - 200 mg,
Lisebelisoa tse thusang: sodium chloride - 900 mg, edetate ea disodium - 10 mg, lactic acid - 75 mg, citric acid monohydrate - 12 mg, sodium hydroxide - 8 mg, hydrochloric acid - 0,0231 ml, metsi bakeng sa ente - ho fihlela 100 ml.

Sebopeho sa 1 ml ea marotholi a mahlo se kenyeletsa:

Lintho tse sebetsang: ciprofloxacin - 3 mg (ka tsela ea ciprofloxacin hydrochloride - 3.49 mg),
Likarolo tse thusang: edodate ea disodium - 0,5 mg, hydrochloric acid - 0,03234 mg, chloride ea sodium - 9 mg, benzalkonium chloride 50% tharollo - 0.0002 ml, metsi bakeng sa ente - ho fihla ho 1 ml.

Matšoao a ho sebelisoa

Ciprolet ka mokhoa oa litafole le tharollo ea infusion e laetsoe kalafo ea mafu a tšoaetsanoang le a tšoaetsanoang a bakoang ke likokoana-hloko tse amehang ketsong ea ciprofloxacin, ho kenyelletsa:

Tšoaetso ea liphatsa tsa lefutso, tšubuhletso ea ho phefumoloha, mokhoa oa ho ntša metsi le liphio, litho tsa ENT, ducts ea bile le lesapo la nyooko, letlalo, lisele tse bonolo le membrane ea mucous, system ea musculoskeletal, pampitšana ea gastrointestinal (ho kenyeletsa meno, molomo, mohlahare)
Peritonitis
Sepsis.

Setlhare se boetse se sebelisoa kalafo le ho thibela ts'oaetso ho bakuli ba nang le ts'oaetso e fokotsang (nakong ea ts'ebeliso ea li-immunosuppressants).

Lerotholi la mahlo le laeloa mafu a tšoaetsanoang le a tšoaetsanoang a leihlo le likhakanyo tsa lona tse bakoang ke libaktheria tse amehang ketsong ea moriana, ho kenyelletsa:

Blepharitis, blepharoconjunctivitis,
Conjunctivitis (subacute le a hlobaetsang),
Alcacteral corneal ulcers,
Dacryocystitis e sa feleng le meibomite,
Keratoconjunctivitis le bakteria keratitis.

Ho boetse ho bontšoa maratso bakeng sa properlaxis ea peleng le kalafo ea mathata a tšoaetsanoang ka mor'a ts'ebetso ea methapo ea mahlo le bakeng sa mathata a mahlo a tšoaetsanoang ka mor'a ho ts'oara litopo tsa basele kapa likotsi (kalafo le thibelo).

Contraindication

Virer keratitis (bakeng sa marotholi a mahlo),
Pseudomembranous colitis (bakeng sa matlapa le tharollo ea infusion),
Glucose-6-phosphate dehydrogenase e haellang (bakeng sa tharollo ea infusion),
Lilemo ho isa ho selemo se le seng (bakeng sa marotholi a mahlo) kapa ho fihlela lilemo tse 18 (bakeng sa matlapa le tharollo ea infusion).

Contraindication bakeng sa mefuta eohle ea tokollo:

Bokhachane le pelehi
Hypersensitivity ho likarolo tsa lithethefatsi kapa lithethefatsi tse ling ho tsoa sehlopheng sa fluoroquinolones.

Ka tlhokomeliso, Tsiprolet e lokela ho fuoa mefuta eohle ea litekanyetso ho bakuli ba nang le lefu la methapo ea methapo ea methapo, likotsi tsa methapo ea methapo le lefu la methapo.

Kahare le kahare, moriana o lokela ho sebelisoa ka hloko ho bakuli ba tsofetseng, hammoho le lefu la sethoathoa, bokuli ba kelello, ho hloleha ho matla ha hepatic le / kapa ho ba le liphio.

Tekanyetso le tsamaiso

Tekanyo ea Ciprolet e khethoa ka mokhoa oa ho lokolla moriana, boteng ba lefu lena, mofuta oa ts'oaetso, boemo ba 'mele, boima ba' mele, lilemo le boemo ba tšebetso ba liphio.

Ciprolet ka mokhoa oa litafole e nooa ka molomo, ka mpeng e se nang letho, e nang le metsi a mangata.

Ka molao, mokhoa o latelang oa litekanyetso o behiloe:

Maloetse a sa sebetseng hantle a methapo ea methapo ea methapo le a liphio, mafu a pampiri e fokolang ea ho hema ka mokhoa o leka-lekaneng: makhetlo a 2 ka letsatsi, 250 mg ka 'ngoe, maemong a matla a lefu lena, tekanyo e le' ngoe e ka eketseha ka makhetlo a 2,
Mokotla: 250-500 mg hang,
Maloetse a lefu la gynecological, enteritis le colitis e nang le thupelo e matla le feberu e matla, prostatitis, osteomyelitis: makhetlo a 2 ka letsatsi, 500 mg ka 'ngoe (kalafo ea lets'ollo le tloaelehileng, tekanyetso e le' ngoe e ka fokotsoa ka makhetlo a 2).

Nako ea kalafo e khethoa ke boteng ba lefu lena, empa Ciprolet e lokela ho nkuoa bonyane matsatsi a mabeli kamora ho nyamela hoa matšoao a lefu lena. Ka karolelano, bolelele ba thupelo ke matsatsi a 7-10.

Haeba ho e-ba le ts'oaetso e matla ea masapo, 1 /₂ tekanyetso ea moriana.

Ha a sa sebetse hantle haholo ke lefu la 'mele, phekolo ea tekanyetso e khethoa ke tumello ea "tlhahiso"

Ho feta 50 ml ka motsotso: litekanyetso tse tloaelehileng
30-50 ml ka motsotso: Nako e le 'ngoe ka lihora tse 12, 250-500 mg ka' ngoe,
5-29 ml ka motsotso: hang ka mor'a lihora tse 18, 250-500 mg.

Bakuli ba nang le dialysis ea hemo- kapa peritoneal dial e tsamaisoa hang ka mor'a lihora tse ling le tse ling tse 24 ka 250-500 mg (kamora ho ts'oaroa ha dialysis).

Ciprolet ka mokhoa oa tharollo ea infusion e tsamaisoa ka mokhoa o kenang kahare bakeng sa metsotso e 30 (200 mg ka ngoe) le metsotso e 60 (400 mg ka ngoe).

Tharollo ea infusion e lumellana le tharollo ea Ringer, tharollo ea sodium chloride ea 0,9%, tharollo ea 10%, 10% le 10% dextrose, hammoho le tharollo e nang le 5% dextrose solution le 0,45% kapa 0,225% sodium chloride.

Karolelano ea tekanyetso e le 'ngoe ke 200 mg (bakeng sa tšoaetso e matla - 400 mg), khafetsa ea tsamaiso - makhetlo a 2 ka letsatsi. Nako ea kalafo e khethoa ke botebo ba lefu lena le makhetlo a 7-14 matsatsi. Haeba ho hlokahala, moriana o ka sebelisoa bakeng sa nako e telele ho feta.

Ha ho phekoloa lefu la makhopho a hlobaetsang, ho bontšoa taolo e le 'ngoe ea methapo e 100 mg ea tharollo.

Bakeng sa thibelo ea tšoaetso ea postoperative, Ciprolet e fanoa kahare ho 200-400 mg metsotso e 30-60 pele a buuoa.

Cyprolet ka mokhoa oa marotholi a mahlo e sebelisoa ka ho khetheha.

Bakeng sa ts'oaetso e lekanang le e matla le e bonolo, lihora tse ling le tse ling tse 4, marotholi a 1-2 a kenngoa ka sejelong sa leihlo le amehang, maemong a tebileng, marotholi a mabeli hora e 'ngoe le e' ngoe. Kamora ntlafatso, khafetsa ea li-instillations le lethalamo lia fokotsoa.

Ka kalafo ea libaktheria tsa ka mpeng lisele tse boletsoeng:

Letsatsi la pele: metsotso e meng le e meng e 15, ho theoha e le ngoe bakeng sa lihora tse 6, ka mor'a metsotso e meng le e meng e 30 nakong ea ho tsoha, ho theoha ka 1,
Letsatsi la bobeli - hora e 'ngoe le e' ngoe nakong ea lihora tsa ho tsoha, lerotholi le le leng,
Letsatsi la 3-14, - lihora tse ling le tse ling tse 4 ka nako ea lihora tse matla, ho theoha ha 1.

Haeba kamora matsatsi a 14 a ho hlatsuoa kalafo ho sa etsahale, kalafo e ka tsoela pele.

Litlamorao

Nakong ea ts'ebeliso ea Ciprolet kahare le kahare, litlamorao tse latelang li ka hlaha:

Ts'ebetso ea pelo: pelo ea methapo, tachycardia, ho theola khatello ea mali, ho tlatsa sefahleho,
Sisteme ea urinary: interstitial nephritis, hematuria, crystalluria (haholo-holo ka mokokotlo o fokolang oa mokokotlo le alkaline), glomerulonephritis, polyuria, dysuria, albinuria, ho boloka methapo, ho tsoa mali,
Sistimi ea musculoskeletal: Riptures ea tendon, arthralgia, tendovaginitis, ramatiki, myalgia,
Hematopoietic system: thrombocytosis, granulocytopenia, leukopenia, thrombocytopenia, anemia, leukocytosis, hemolytic anemia,
Ts'oaetso ea ho ja: ho ipolaisa tlala, ho opeloa ke mpa, ho nyekeloa, ho hlatsa, lets'ollo, lefufuru, cholestatic jaundice (haholoholo ho bakuli ba nang le mafu a sebete a fetileng), hepatonecrosis, hepatitis, ketsahalo e eketsehang ea hepatic transaminases le alkaline phosphatase,
Tsamaiso ea methapo ea kutlo: hlooho ea hlooho, ho tsekela, ho thothomela, ho ferekana, ho hlobaela, ho opeloa ke lefu le sa foleng, ho eketsa khatello ea kelello, ho ruruha, ho tšoenyeha, khatello ea maikutlo, pherekano, lipono tse ling le lintho tse ling tse hlahisang maikutlo a kelello. ba ka tsoella maemong ao mokuli a khonang ho intša kotsi), a akheha, migraine, mokokotlo oa mokokotlo,
Litho tsa kutlo: kutlo ea kutlo, tinnitus, monko o sa thabiseng le tatso, ho senyeha ha pono (diplopia, phetoho ponong ea mebala),
Matšoao a laboratori: hypercreatininemia, hypoprothrombinemia, hyperglycemia, hyperbilirubinemia,
Litla-morao: ho hlahella ha leqhubu la marang-rang a manyane le marapo a tsamaeang le ho tsoa mali, ho hlohlona ha letlalo, feberu ea lithethefatsi, urticaria, hemorrhages (petechiae), vasculitis, phepelo ea laryngeal kapa sefahleho, eosinophilia, ho hema hanyane, ho eketseha hoa moea. genermal necrolysis (lefu la Lyell), lefu la Stevens-Johnson (malignant exudative erythema),
Tse ling: bofokoli bo akaretsang, bonohe (candidiasis, pseudomembranous colitis).

Ka tsamaiso ea methapo, methapo ea lehae e ka hlaha, e bonahatsoa ke bohloko le ho chesa sebakeng sa ente, nts'etsopele ea phlebitis.

Ha o sebelisa Ciprolet ka mokhoa oa marotholi a mahlo, ho ka hlaha mathata a latelang:

Setho sa pono: ho chesa, ho hlohlona, hyperemia le bonolo ba mokokotlo oa conjunctiva, seoelo ho nka lifoto, ho ruruha ha mahlo, ho fifala, maikutlo a 'mele a tsoang ka ntle mahlong a fokotsehile, ho bonahala ka mokhoa o hlakileng oa kristale e hlahang ho bakuli ba nang le lisele tsa mokokotlo, keratopathy, keratitis,
Tse ling: ho nyekeloa ke pelo, ho kulisoa ke lintho tse sa tloaelehang, hangata - nts'etsopele ea bonohe, litholoana tse mpe tse sa thabiseng molomong hanghang ka mor'a ho kenella.

Litaelo tse khethehileng

Bakeng sa bakuli ba nang le nalane ea ho ts'oaroa, nalane ea ho ts'oaroa, maloetse a methapo ea mokokotlo le ho senyeha ha boko ka lebaka la kotsi ea karabelo e mpe e tsoang ho tsamaiso ea methapo e kholo, Tsiprolet kahare e lokela ho laeloa feela ka mabaka a bophelo bo botle.

Haeba nakong ea ts'ebeliso ea lithethefatsi kapa lets'oao, lets'ollo la nako e telele kapa le tebileng le hlaha kahare kapa kahare, ho bohlokoa ho kenyelletsa boteng ba pseudomembranous colitis, e hlokang ho tlosoa kapele ea Ciprolet le ho khethoa ha kalafo e nepahetseng. Phekolo e lokela ho emisoa ka nts'etsopele ea bohloko ka har'a tendon kapa ka lipontšo tsa pele tsa tenosynovitis.

Nakong ea ts'ebeliso ea lithethefatsi ka mokhoa oa litafole le tharollo ea ho kenella, metsi a lekaneng a lokela ho fanoa ha a ntse a shebile diuresis e tloaelehileng.

Lirosa tsa mahlo li ka sebelisoa feela ka hlooho, ho ke ke ha khoneha ho kenya sethethefatsi ka kamoreng e ka ntle ea leihlo kapa subconjunctival. Ha o sebelisa lithethefatsi le tharollo e meng ea mahlo, nako e pakeng tsa tsamaiso ea tsona e lokela ho ba bonyane metsotso e 5. Ho roala lilense tsa khokahano ha ho khothalletsoe nakong ea phekolo.

Ha u sebelisa Ciprolet, tlhokomelo e lokela ho nkoa ha u khanna le ho etsa mefuta e meng e ka bang kotsi ea mosebetsi e hlokang tlhokomelo e phahameng le karabelo e potlakileng ea psychomotor (haholo-holo hammoho le joala).

Ho sebelisana le lithethefatsi

Tabeng ea tšebeliso e tšoanang ea Ciprolet ka lithethefatsi tse ling, ho ka hlaha litlamorao tse sa rateheng:

Didanosine: ho fokotseha ho amoheloa ha ciprofloxacin,
Theophylline: keketseho ea khatello ea eona ea mali le monyetla oa ho ba le chefo,
Li-antacid, hammoho le litokisetso tse nang le zinc, aluminium, magnesium kapa ion ea tšepe: phallo e fokotsoang ea koprofloxacin (nako e pakeng tsa tšebeliso ea lithethefatsi tsena e lokela ho ba bonyane lihora tse 4),
Li-anticoagulants: Nako e telele ea ho tsoa mali,
Cyclosporin: lephrotoxicity e eketsehileng,
Lithethefatsi tse seng khahlanong le ho ruruha (ntle le acetylsalicylic acid): kotsi ea ho ts'oaroa,
Metoclopramide: ho potlakisa ho koaloa ha ciprofloxacin,
Litokisetso tsa uricosuric: Ho lieha ho felisoa le ho eketsoa hoa plasma bongata ba ciprofloxacin,
Anticoagulants e sa tobang: ho ntlafatsa ketso ea bona.

Ka tšebeliso e tšoanang ea Ciprolet le lithethefatsi tse ling tsa antimicrobial, ts'ebelisano e ka etsahala. Ho latela ts'oaetso, Ciprolet e ka sebelisoa hammoho le litlhare tse latelang:

Azlocillin, ceftazidime: ts'oaetso e bakoang ke Pseudomonas spp.,
Meslocillin, azlocillin le lithibela-mafu tse ling tsa beta-lactam: ts'oaetso ea lefutso la streptococcal,
Isoxazolylpenicillins le vancomycin: ts'oaetso ea staph,
Metronidazole, clindamycin: ts'oaetso ea anaerobic.

Solution solution ea infroletic ha e lumellane ka litlhare le litlhare tsohle le tharollo ea infusion e sa tsitsang tlasa maemo a acidic (pH ea tharollo ea infusion ea ciprofloxacin ke 3.5-4.6). Ho ke ke ha khoneha ho kopanya tharollo bakeng sa tsamaiso ea methapo le tharollo moo pH e kholo ho feta 7.