Siofor e nkuoe ho tsoa ho eng le hore na ke mofuta ofe oa lithethefatsi: mochini oa ketso, mofuta oa tokollo le litekanyetso

Foromo ea litekanyetso - matlapa a maputsoa a tšoeu:

Siofor 500: pota, biconvex (li-pcs tse 10. Ka marang-rang, mokotleng oa karete ea 3, 6 kapa 12,
Siofor 850: oblong, e nang le notch e nang le mahlakore a mabeli (li-pcs tse 15. Ka marang-rang, mokotleng oa karete ea 2, 4 kapa 8 malebela),
Siofor 1000: oblong, e nang le notch ka lehlakoreng le leng e nang le "snap-tab" tafoleng e ngoe ka lehlakoreng le leng (li-pcs tse 15.)... Lithupa, ka lebokoseng la mekotla ea 2, 4 kapa 8 malebela.

Sesebelisoa se sebetsang sa lithethefatsi ke metformin hydrochloride, ka har'a letlapa le le leng le na le 500 mg (Siofor 500), 850 mg (Siofor 850) kapa 1000 mg (Siofor 1000).

Baeti: povidone, hypromellose, magnesium stearate,
Sebopeho sa Shell: macrogol 6000, hypromellose, titanium dioxide (E171).

Matšoao a ho sebelisoa

Siofor e etselitsoe phekolo ea mofuta oa lefu la tsoekere la mofuta oa II, haholo-holo ho bakuli ba boima bo feteletseng ba ikoetlisang ba sa sebetseng hantle le kalafo ea ho ja.

E ka sebelisoa e le sethethefatsi se le seng kapa e le karolo ea kalafo e rarahaneng hammoho le insulin le baemeli ba bang ba molomo ba hypoglycemic.

Tekanyetso le tsamaiso

Moriana o lokela ho nooa ka molomo nakong ea lijo kapa hang ka mor'a moo.

Tsela ea kalafo le litekanyetso li nka qeto ea ngaka ho latela boemo ba tsoekere maling.

Ha u etsa monotherapy, batho ba baholo ba fuoa makhetlo a 500 mg ka makhetlo a mabeli ka letsatsi kapa nako ea 850 mg ka letsatsi. Kamora matsatsi a 10- 10, ha ho hlokahala, tekanyetso ea letsatsi le letsatsi e eketseha butle-butle ho isa matlapeng a 3-4 Siofor 500, matlapa a 2-3 Siofor 850 mg kapa matlapa a 2 a Siofor 1000.

Tekanyetso e kholo ea letsatsi le letsatsi ke 3000 mg (matlapa a 6 a 500 mg kapa matlapa a 3 a 1000 mg) ho tekanyetso tse 3 tse arohaneng.

Ha ho fanoa ka litekanyetso tse phahameng, matlapa a 2 a Siofor 500 a ka nkeloa sebaka ke pilisi e le 'ngoe ea Siofor 1000.

Haeba mokuli a fetisetsoa metformin ho tsoa litlhare tse ling tsa antidiabetic, tse ling lia hlakoloa ebe li qala ho nka Siofor ho litekanyetso tse kaholimo.

Hammoho le insulin (ho ntlafatsa taolo ea glycemic), Siofor e beoa makhetlo a 500 mg ka makhetlo a mabeli ka letsatsi kapa 850 mg hang ka letsatsi. Haeba ho hlokahala, hang ka beke tekanyetso e nyolleloa butle-butle hore e be matlapa a 3-4 Siofor 500, matlapa a mabeli a Siofor 850 kapa matlapa a mabeli a Siofor 1000. Tekanyetso ea insulin e khethoa ho latela boemo ba tsoekere maling. Sekhahla se phahameng sa letsatsi ke 3000 mg ho litekanyetso tse 3 tse arohaneng.

Ha u khetha tekanyetso, bakuli ba tsofetseng ba boetse ba nahanela ho hoheloa ha metabolinine maling a mali. Nakong ea kalafo, ho hlokahala hore ho etsoe tlhahlobo ea kamehla ea renal.

Bana ba lilemo tse 10-18 le monotherapy, mme hammoho le insulin, qalong ea kalafo e behiloe 500 mg kapa 850 mg ea metformin 1 nako ka letsatsi. Haeba ho hlokahala, kamora matsatsi a 10-15, lethalinyana le eketseha butle-butle. Sekhahla se phahameng sa letsatsi ke 2000 mg (matlapa a 4 a 500 mg kapa matlapa a 2 a 1000 mg) ho litekanyetso tse peli.

Tekanyo e hlokahalang ea insulin e khethoa ho latela boemo ba tsoekere maling.

Litlamorao

Litla-morao: Ha se hangata - urticaria, ho hlohlona, hyperemia,
Sistimi e nang le methapo: hangata - tatso ea pherekano,
Letšoao la sebete le biliary: litlaleho tse arohaneng - keketseho e phetoho mosebetsing oa manonyeletso a amanang le hepatic, hepatitis (feta kamora ho tlosoa hoa lithethefatsi),
Metabolism: ka seoelo - lactic acidosis, ka tšebeliso ea nako e telele - ho fokotseha ha ho kenngoa ha vithamine B e ngata₁₂ le phokotso ea khatello ea mali maling a mali (menyetla ea karabelo ena e lokela ho tsotelloa ha ho fanoa ka litlhare ho bakuli ba nang le anemia ea megaloblastic),
Sistimi ea lijo: Ho hloka takatso ea lijo, tatso ea tšepe molomong, ho nyekeloa ke pelo, ho hlatsa, bohloko ba ka mpeng, lets'ollo. Matšoao ana a hlaha hangata qalong ea kalafo, 'me hangata a itlhahela a le mong. Ho li thibela, o lokela ho eketsa tekanyetso ea letsatsi le letsatsi butle-butle, o e arole ka litekanyetso tse 2, 'me u noe setheoana ka lijo kapa hang ka mor'a moo.

Litaelo tse khethehileng

Siofor ha e nke sebaka sa lijo tsa ho ja le ho ikoetlisa letsatsi le leng le le leng - mekhoa ena ea kalafo eo eseng ea lithethefatsi e tlameha ho kopantsoe le moriana ho latela likhothaletso tsa ngaka e eang. Bakuli bohle ba lokela ho latela mokhoa oa ho ja o nang le phepo e nepahetseng ea lik'habohaedreite letsatsi lohle, 'me batho ba nang le boima bo bongata ba mmele ba lokela ho ja lijo tse nang le khalori e tlase.

Haeba u belaella nts'etsopele ea lactic acidosis, ho hlokahala hore ho tlosoe hanghang lithethefatsi le sepetlele sa tšohanyetso sa mokuli.

Metformin e pepesoa ke liphio, kahoo pele e qala kalafo le hona ts'ebetsong ea eona, ts'oaetso ea "creatinine" ka plasma ea mali e lokela ho khethoa. Ho shebella ka mokhoa o ikhethileng ho hlokahala haeba ho na le kotsi ea ts'ebetso ea ho lemala ho sa sebetseng hantle, ka mohlala, qalong ea ts'ebeliso ea lithethefatsi tse seng lithethefatsi tse seng tsa antiidal kapa tse antihypertensive.

Haeba ho hlokahala ho etsa tlhahlobo ea X-ray ka tsamaiso ea methapo ea moemeli ea nang le iodine e nang le iodine ka nakoana, Siofor ka nakoana (lihora tse 48 pele le lihora tse 48 kamora ts'ebetso) li lokela ho nkeloa sebaka ke sethethefatsi se seng sa hypoglycemic. Ho lokela ho etsoa se tšoanang ha ho fanoa ka ts'ebetso e reriloeng ea ts'ebetso ea ts'ebetso ea ts'ebetso e thibelang opereishene ka kakaretso, e nang le lefu la ho bola kapa la mokokotlo.

Ho latela liteko tsa bongaka tse laoloang tsa selemo se le seng, metformin ha e ame kholo, kholo le ho kena bohlankaneng ba bana. Leha ho le joalo, ha ho na datha mabapi le matšoao ana a nang le kalafo e telele, ka hona, bana ba fumanang Siofor, haholo nakong ea pelehi (lilemo tse 10-12), ba hloka tlhaiso e khethehileng.

Monotherapy le Siofor ha e lebise ho hypoglycemia. Ka kalafo ea ho kopanya (hammoho le insulin kapa lintho tse tsoang ho sulfonylurea) ho na le monyetla o joalo, ka hona, tlhokomeliso e tlameha ho sebelisoa.

Siofor, e sebelisoang e le setheoana se le seng, ha e ame phoso ea lebelo le matla a ho sisinyeha. Ha u sebelisa metformin e le karolo ea kalafo e rarahaneng, ho na le monyetla oa ho ba le maemo a hypoglycemic, ka hona, tlhokomeliso e lokela ho sebelisoa ha u etsa lintho tse ka bang kotsi, ho kenyeletsa ha u khanna makoloi.

Ho sebelisana le lithethefatsi

Metformin e hanyetsanoa nakong ea lithuto le tsamaiso ea methapo ea methapo e nang le iodine e fapaneng.

Ha ho kgothaletswe ho nwa lino tse tahang le ho nka lithethefatsi tse nang le ethanol nakong ea kalafo, kaha kotsi ea ho ba le lactic acidosis e eketseha, haholoholo ka ho hloleha ha sebete, khaello ea phepo e nepahetseng kapa ho ja.

Mekhaako e hlokang ho ba hlokolosi mabapi le mekhoa e ka bang teng pakeng tsa litšebelisano:

Danazole - nts'etsopele ea phello ea hyperglycemic,
Angiotensin-converting enzyme inhibitors le lithethefatsi tse ling tsa antihypertensive - li theola tsoekere ea mali,
Lihormone tsa qoqotho, lithibela-pelehi tsa molomo, nicotinic acid, tsoekere, epinephrine, litlamorao tse tsoang maling -
Nifedipine - ho monya ho eketsehileng le khatello e phahameng ea metformin maling a mali, ho lelefatsa mantle a eona,
Cimetidine - e liehisa ho felisoa ha metformin, e eketsa kotsi ea lactic acidosis,
Salicylates, sulfonylurea derivatives, insulin, acarbose - eketseha hypoglycemic phello,
Lithethefatsi tsa Cationic (procainamide, morphine, quinidine, triamteren, ranitidine, vancomycin, amiloride) tse bolokiloeng ka har'a li-tubules - keketseho ea palo e phahameng ea metformin ho plasma ea mali,
Furosemide - ho fokotseha ha maikutlo a eona le halofo ea bophelo ba bona,
Anticoagulants e sa tobang - e fokolisa ketso ea bona,
Li-agonists tsa Beta-adrenergic, diuretics, glucocorticoids (bakeng sa ts'ebeliso ea kemiso le ea li-topical) - keketseho ea tsoekere ea mali.