Berlition 300: litaelo tsa tšebeliso

ka har'a likhalase tsa khalase tse sootho tsa 12 ml, ka lebokoseng la karete ea li-ampoules tse 5, 10 kapa 20.

ka mokotla oa lithutsoana tsa li-pcs tse 10, ka lebokoseng la karete ea lipakete tse 3, 6 kapa 10.

Ketso ea pharmacological

Ha e le coenzyme ea mitochondrial multenzyme complexes, e nka karolo ho oxidative decarboxylation ea pyruvic acid le alpha-keto acid. E thusa ho fokotsa tsoekere ea mali le ho eketsa glycogen ho sebete, hammoho le ho hlola insulin.
Ka mofuta oa ts'ebetso ea biochemical, e haufi le livithamini tsa B. E nka karolo taolong ea metabolism ea lipid le carbohydrate, e matlafatsa metabolism ea cholesterol, mme e ntlafatsa ts'ebetso ea sebete. Tšebeliso ea letsoai la trometamol la thioctic acid (ho ba le karabelo e sa nke lehlakore) tharollo bakeng sa tsamaiso e kenelletseng e ka fokotsa botebo ba karabelo e mpe.

Mofumahali

Ha e nooa ka molomo, e kenella ka potlako le ka botlalo ho tsoa pampiring ea mala (ho ja ka lijo ho fokotsa ho monya). Nako ea ho fihla C_max - 40-60 metsotso Bioavailability ke 30%. E na le phello ea "mokhoa oa pele" ka sebete. Ho thehoa ha metabolites ho etsahala ka lebaka la oxidation ea lehlakore le thipa. Boholo ba kabo e ka ba 450 ml / kg. Litsela tse kholo tsa metabolic ke oxidation le conjugation. Thioctic acid le metabolites ea eona li hlahisoa ke liphio (80-90%). T_1/2 - Metsotso e 20-50 Kakaretso ea plasma Cl - 10-15 ml / min.

Litlamorao

Tharollo ea ente: ka linako tse ling ho ikutloa eka o boima hloohong le ho hema ka thata (ka potlako ho / ho tsamaiso). Boitšoaro ba ho kulisa bo ka etsahala setsing sa ente se nang le ho bonahala urticaria kapa sensation e tukang. Maemong a mang, ho hlohlona, ​​diplopia, hemorrhages e supang letlalong le mucous membrane.
Matlapa a kopaneng: maemong a mang, letlalo le hanana le lona.

Ho fokotseha ha tsoekere ea mali hoa khoneha.

Tekanyetso le tsamaiso

Iv. Ka matla I / O polyneuropathies, 12 - 24ml (300-600 mg ea alpha-lipoic acid) ka letsatsi bakeng sa libeke tse 2-5. Bakeng sa sena, li-ampoules tsa 1-2 tsa moriana li hlapolotsoe ka 250 ml ea tharollo ea sodium chloride le ho tsamaisoa ka tlase ho metsotso e ka bang 30. Nakong e tlang, ba fetoha pheko ea tlhokomelo le Berlition 300 ka mokhoa oa lipilisi ka lethal dose ea 300 mg ka letsatsi.

Bakeng sa kalafo ea polyneuropathy - 1 tafole. Makhetlo a 1-2 ka letsatsi (300-600 mg ea alpha-lipoic acid).

Litlhokahalo tsa polokeho

Nakong ea kalafo, motho o lokela ho hana ho sebelisa lino tse tahang (joala le lihlahisoa tsa lona li fokolisa phello ea kalafo).

Ha o sebelisa sethethefatsi, o lokela ho lekola boemo ba tsoekere ea mali khafetsa (haholo-holo mohato oa pele oa kalafo). Maemong a mang, ho thibela matšoao a hypoglycemia, ho ka hlokahala ho fokotsa tekanyetso ea insulin kapa moemeli oa antidiabetesic ea molomo.

Sokolla foromo le sebopeho

Berlition e hlahisoa ka mokhoa oa matlapa a koahetsoeng, matlapa a 30 ka sephutheloana (3 malepa a matlapa a 10). Mefuta e meng ea tokollo e kenyelletsa likhalase tsa gelatin bakeng sa tšebeliso ea kahare, ho tsepamisa mohopolo ha ho etsoa tharollo ea infusion.

Sesebelisoa sa mantlha se sebetsang ke thioctic (alpha-lipoic) acid. Letlapa le le leng le na le 300 mg ea thioctic acid.

Likarolo tse thusang: "microcrystalline cellulose" colloidal silicon dioxide, lactose monohydrate, sodium ea croscarmellose, magnesium stearate, povidone.

Contraindication

Lintho tse amanang le tšebeliso ea Berlition ke:

• hypersensitivity reaction kapa ho se mamelle alpha-lipoic acid kapa e 'ngoe ea likarolo tse thusang tsa lithethefatsi.
• tlolo ea ho monya ha glucose-galactose, galactosemia, khaello ea lactase,
• ho ima le ho nyekeloa,
• ea lilemo tse ka tlase ho 18.

Tekanyetso le tsamaiso

Matlapa a Berlition a nooa ka molomo ka kakaretso, ha a sithapuoe kapa hona ho hlafuna. Moriana o nooa hang ka letsatsi, hoseng, halofo ea hora pele ho lijo tsa hoseng.

Phekolo e telele. Tsela ea kalafo e khethoa ke ngaka ka bonngoe, ho latela matšoao le boemo ba mokuli.

Ho lefu la tsoekere la polyneuropathy, alpha-lipoic acid e fanoa ka tekanyetso ea 600 mg ka letsatsi.

Bakeng sa mafu a sebete, litekanyetso tsa letsatsi le letsatsi tsa lithethefatsi ho batho ba baholo li tloha ho 600 mg ho isa ho 1200 mg.

Litaelo tse khethehileng

Nakong ea kalafo le Berlition, ho lokela ho tsotelloa tse latelang:

• mehatong ea pele ea kalafo ho bakuli ba nang le polyneuropathy, ho eketseha ha paresthesia ho ka etsahala,
• Bakuli ba nang le lefu la tsoekere ha ba ntse ba sebelisa litafole ba hloka ho lekoloa khafetsa maemo a tsoekere ea mali le, haeba ho hlokahala, ho lokisoa ha litekanyetso tsa lithethefatsi tsa antidiabetes.
• o ka se noe joala nakong ea kalafo,
• Ha ho na data mabapi le phello ea alpha-lipoic acid ho lesea le mmele oa ngoana, ka hona, sethethefatsi ha se laeloe nakong ea kemaro le ho anyesa.

Ho sebelisana le lithethefatsi ka tšebeliso e tšoanang.

• kalafo e amang cospastine e fokotsehile,
• litlamorao tsa lithethefatsi tse hypoglycemic li eketseha,
• Ka lisebelisoa tsa tšepe, ho kenyelletsoa le magnesium, tšepe, le calcium, alpha-lipoic acid e kopanya likarolo tse rarahaneng, ka hona, ts'ebeliso ea litokisetso tse nang le likarolo tsena, hammoho le ts'ebeliso ea lihlahisoa tsa lebese, li lumelloa feela lihora tse 6-8 kamora ho nka Berlition.

Liphetoho tsa lithethefatsi (tse nang le ntho e le 'ngoe e sebetsang) li kenyelletsa: Alpha Lipon, Dialipon, Thioctodar, Tiogamm, Espa-Lipon, Thioctacid BV.