Sebopeho le boqapi ba "Protafan", litaelo tsa tšebeliso, litekolo mabapi le lithethefatsi, theko ea tsona
Leqephe lena le fana ka lethathamo la li-analogues tsohle tsa Protafan ka sebopeho le sesupo sa tšebeliso. Lethathamo la li-analogues tse theko e tlaase, hape u ka bapisa litheko libakeng tsa meriana.
- Analogue e theko e tlaase ka ho fetisisa ea Protafan:Humulin nph
- Analogue e tummeng ka ho fetisisa ea Protafan:Biosulin N
- Sehlopha sa ATX: Insulin (ea motho)
# | Sehlooho | Theko ho la Russia | Theko Ukraine |
---|---|---|---|
1 | Humulin nph insulin ea motho Analogue ka sebopeho le pontsho | 166 rub | 205 UAH |
2 | Biosulin N Sebopeho le analogue ea tlhahiso | 200 rub | -- |
3 | Protafan NM insulin ea motho Analogue ka sebopeho le pontsho | 356 rub | 116 UAH |
4 | Rinsulin NPH insulin ea motho Analogue ka sebopeho le pontsho | 372 rub | -- |
5 | Protfera NM Penfill insulin ea motho Analogue ka sebopeho le pontsho | 857 rub | 590 UAH |
Ha u bala litšenyehelo cheap protafan analogue theko e fokolang e fumanoeng lenaneng la theko e fanoeng ke li-pharmacies e ile ea tsotelloa
# | Sehlooho | Theko ho la Russia | Theko Ukraine |
---|---|---|---|
1 | Biosulin N Sebopeho le analogue ea tlhahiso | 200 rub | -- |
2 | Humulin nph insulin ea motho Analogue ka sebopeho le pontsho | 166 rub | 205 UAH |
3 | Rinsulin NPH insulin ea motho Analogue ka sebopeho le pontsho | 372 rub | -- |
4 | Protafan NM insulin ea motho Analogue ka sebopeho le pontsho | 356 rub | 116 UAH |
5 | Insuman Bazal insulin ea motho Analogue ka sebopeho le pontsho | 1170 rub | 100 UAH |
E fuoe lenane la lingaka tsa lithethefatsi e ipapisitse le lipalo-palo tsa litlhare tse kopiloeng ka ho fetisisa
Li-analog mabapi le sebopeho le pontšo ea ts'ebeliso
Sehlooho | Theko ho la Russia | Theko Ukraine |
---|---|---|
Biosulin N | 200 rub | -- |
Insuman basal insulin ea motho | 1170 rub | 100 UAH |
Humodar b100r insulin ea motho | -- | -- |
Humulin insulin insulin | 166 rub | 205 UAH |
Gensulin N insulin ea motho | -- | 123 UAH |
Insugen-N (NPH) insulin ea motho | -- | -- |
Protafan insulin ea motho ea sireletso NM | 356 rub | 116 UAH |
Protafan NM Penfill insulin | 857 rub | 590 UAH |
Rinsulin NPH insulin | 372 rub | -- |
Farmasulin N NP insulin ea motho | -- | 88 UAH |
Insulin Stabil Human Recombinant Insulin | -- | 692 UAH |
Lethathamo le ka holimo la li-analogues tsa lithethefatsi, tse bonts'ang Protafan emang, e loketse haholo hobane e na le sebopeho se tšoanang sa lintho tse sebetsang ebile e lumellana ho latela sesupo sa tšebeliso
Moetso o fapaneng o kanna oa lumellana ho bonts'a mokhoa le mokhoa oa kopo
Sehlooho | Theko ho la Russia | Theko Ukraine |
---|---|---|
Insulin | 178 rub | 133 UAH |
Actrapid | 35 rub | 115 UAH |
Actrapid nm | 35 rub | 115 UAH |
Actrapid nm khokahano | 469 rub | 115 UAH |
Biosulin P | 175 rub | -- |
Insuman Rapid Insulin ea Batho | 1082 rub | 100 UAH |
Humodar p100r insulin ea motho | -- | -- |
Humulin insulin ea kamehla ea motho | 28 rub | 1133 UAH |
Farmasulin | -- | 79 UAH |
Gensulin P insulin | -- | 104 UAH |
Insugen-R (Kamehla) insulin ea motho | -- | -- |
Rinsulin P "insulin" ea motho | 449 rub | -- |
Farmasulin N insulin ea motho | -- | 88 UAH |
Insulin Asset insulin ea motho | -- | 593 UAH |
Monodar insulin (nama ea kolobe) | -- | 80 UAH |
Humalog insulin lispro | 57 rub | 221 UAH |
Lispro insulin e kopantseng Lispro | -- | -- |
NovoRapid Flexpen Pen Insulin Aspart | 28 rub | 249 UAH |
NovoRapid penfill insulin aspart | 1601 rub | 1643 UAH |
Epidera Insulin Glulisin | -- | 146 UAH |
Apidra SoloStar Glulisin | 447 rub | 2250 UAH |
Humodar k25 100r insulin ea motho | -- | -- |
Gensulin M30 insulin ea motho | -- | 123 UAH |
Insugen-30/70 (Bifazik) insulin ea motho | -- | -- |
Insuman Comb insulin ea motho | -- | 119 UAH |
Mikstard insulin ea motho | -- | 116 UAH |
Mixtard Penfill Insulin Motho | -- | -- |
Farmasulin N 30/70 insulin ea motho | -- | 101 UAH |
Humulin M3 insulin | 212 rub | -- |
Humalog Remix insulin lispro | 57 rub | 221 UAH |
Novomax Flekspen insulin aspart | -- | -- |
Ryzodeg Flextach insulin aspart, insludec ea insulin | 6 699 rub | 2 UAH |
Lantus insulin glargine | 45 rub | 250 UAH |
Lantus SoloStar insulin glargine | 45 rub | 250 UAH |
Tujeo SoloStar insulin glargine | 30 rub | -- |
Levemir Penfill insulin | 167 rub | -- |
Levemir Flexpen Pen Insulin Detemir | 537 rub | 335 UAH |
Tresiba Flextach Insulin Degludec | 5100 rub | 2 UAH |
U ka fumana analogue e theko e tlaase ea moriana o theko e phahameng?
Ho fumana analogue e theko e phahameng ea moriana, mofuta oa generic kapa lebitso, pele ho tsohle re khothaletsa ho ela hloko sebopeho, e leng lintho le lipontšo tse tšoanang tse sebetsang. Metsoako e tšoanang ea lithethefatsi e tla bonts'a hore lithethefatsi li tsamaisana le lithethefatsi, li ka lekana meriana kapa li ka etsa meriana. Leha ho le joalo, u se ke oa lebala ka likarolo tse sa sebetseng tsa lithethefatsi tse tšoanang, tse ka amang polokeho le ts'ebetso. Se ke la lebala ka litaelo tsa lingaka, ho itlama ho ka lematsa bophelo ba hau, ka hona, etela ngaka ea hau kamehla pele u sebelisa meriana leha e le efe.
Theko ea Protafan
Liaeteng tse ka tlase u ka fumana litheko tsa Protafan 'me u fumane hore na ho na le fumaneha ka har'a k'hemiste haufi le moo
- Theko ea Protafan ho la Russia
- Theko ea Protafan e Ukraine
- Theko ea Protafan e Kazakhstan
Fomu ea tokollo
Protafan insulin e fumaneha ka mokhoa oa ho emisoa bakeng sa tsamaiso ea subcutaneous. Ampoules ea Protafana NM Penfill e kenelletse ka mabokoseng a 3 ml. Ho na le likotoana tse 5 ka har'a sephutheloana ka seng. E sebelisoa, pente ea syringe e sebetsang hape bakeng sa Protafan e rekoa ka thoko.
Ho emisoa ho tšoeu. Haeba ho le joalo, e qala ho ikarola, e etse pula e tšoeu ebile e le mokelikeli o se nang 'mala ka holim'a eona. Ka ho ferekana, ha ho sa senyeha.
Pharmacodynamics le pharmacokinetics
"Protafan" ke analogue ea "insulin" ea motho ka nako e telele ea ketso. E hlahisoa ke DNA e kopantsoeng e sebelisa mofuta o ikhethileng. Tekanyo ea glucose e fokotseha ka lebaka la ho monya ho hoholo ha intracellular ka mor'a ho tlangoa ha insulin le li-insulin receptors ho adipose le mesifa ea mesifa. Ka nako e ts'oanang, ho na le phokotseho ea tekanyo ea tlhahiso ea tsoekere maling.
Phello e phahameng ea pharmacological e fihlella ka mor'a lihora tse 4 ho isa ho tse 12 kamora ts'ebetso, phello e phehella hoo e ka bang letsatsi.
Tlhaloso e bonts'a hore ho tlosoa hoa insulin maling le metsotso e seng mekae. Phello ea nako e telele ea lithethefatsi e amana le ho kengoa. Ho latela lintlha tse joalo:
- litekanyetso
- sebaka sa kenyelletso
- tsela ea tsamaiso
- botenya ba mafura a subcutaneous,
- mofuta oa lefu la tsoekere.
Nakong ea lipatlisiso tsa moriana o nang le chefo le kotsi e 'ngoe e ka bang teng' meleng, likotsi tse khethehileng ha li e-so fumanoe.
Matšoao le contraindication
Letšoao le ka sehloohong ke lefu la tsoekere ho batho, le lebisang tlhokong ea kalafo ea insulin, ho sa tsotelehe lilemo tsa sehlopha. Ka mofuta oa 1 oa lefu lena - kalafo e etsoa ho tloha qalong ea mathata a metabolism ea carbohydrate, ka mofuta oa 2 - ha meriana e khethehileng ea molomo e sa fane ka sephetho se lebelletsoeng mme hemoglobin ea glycated e feta 9%. Hape, Protafan e laeloa hore e be le lefu la tsoekere ho basali ba baimana.
Protafan e thibetsoe maemong a latelang:
- allergy e matla
- nalane ea Quincke's edema, e ileng ea hlaha e le karabelo ea insulin e fanoeng,
- tšekamelo ea hypoglycemia.
Litlamorao
Litla-morao tsa Protafan li kenyeletsa maemo a latelang:
- ho fifala ha letlalo,
- mofufutso
- maikutlo a ho otla ha pelo ea motho
- Ho thothomela ka maoto
- tlala
- nyakallo
- hlooho e bohloko
- ho tsekela
- ho sitisoa hoa pono.
Ena ke letšoao la hypoglycemia, nts'etsopele e matla le ho se be teng ha mehato ea ho lokisa ka potlako ho halefisa ho ferekana ha kelello.
Matšoao a ho kula le lithethefatsi ho kenyelletsa:
- makhopho a letlalo,
- anaphylactic makala,
- Edema ea Quincke.
Litla-morao tsa lehae li ka hlaha - ho hlohlona le ho ruruha. Haeba o kenella nako e telele sebakeng se le seng, ho hlaha lipodystrophy.
Tekanyetso le overdose
Setlhare se sebelisoa feela bakeng sa tsamaiso tlasa letlalo. Tekanyetso e khethoa ke ngaka e eang ka bonngoe, e nahanela boemo ba glucose maling.
Tekanyetso e tloaelehileng e tsoa ho 0.5 ho 1 IU / kg ea boima ba mokuli.
Ka li-pathologies tse kopaneng, haholo-holo tsa tlhaho tse tšoaetsanoang le feberu, ho hlokahala hore u ente moriana ka litekanyetso tse eketsehileng.
Phetoho ea moriana e hlokahala bakeng sa tšenyo ho sebete, liphio, litšoelesa tsa adrenal, tšoelesa ea qoqotho kapa gland.
Tekanyetso e fetoloa ka lebaka la ts'ebetso ea 'mele kapa ka lebaka la phetoho ea lijo, ha e fetisoa ho tloha ho tse ling tse lokiselitsoeng insulin.
Hypoglycemia ka lebaka la lithethefatsi tse ngata tse ngata li ka tsoela pele butle butle. Sena se etsahala ha litekanyetso li ntse li fetisoa khafetsa ho tsoa litlhoko tse thehiloeng ke ngaka.
Ho a khonahala ho emisa mefuta e bobebe ea overdose ka boeona ka ho nka tsoekere kapa lijo tse nang le lik'habohaedreite tse bonolo tlatsong. Ka lebaka la kotsi e sa feleng ea hypoglycemia, bakuli ba nang le lefu la tsoekere ba lokela ho lula ba e-na le likarolo tse 'maloa tsa tsoekere kapa lipompong.
Ka ts'ebeliso e feteletseng ea tahlehelo le ho lahleheloa ke kelello, ho fanoa ka 0.5-1 mg ea glucagon. Entcutaneous kapa intravenous ente. Dextrose ke sesebelisoa se matla ho feta - ho latela mokhoa, o tsamaisoa ke setsebi sa bongaka se nang le boiphihlelo ba ho kenya liente.
Tšebelisano
Lefu la tsoekere ke mofuta o sa foleng o atisang ho baka mathata liphatsong le litsamaisong tse fapaneng tsa mmele. Bakeng sa kalafo ea mathata, ho hlokahala kalafo e eketsehileng. Mabapi le taba ena, ho bohlokoa ho tseba hore na lithethefatsi tse ling li na le tšebelisano efe le tšireletso ea insulin. Ngaka e tlameha ho fetola litekanyetso.
Matla a matlafatso ea "Protafan"
- meriana kaofela e nang le ethanol ke sehlopha se seholo, kahoo pele o sebelisa moriana o mong ho molemo ho eketsa tlhahlobo,
- ACE inhibitors - sehlopha sa lithethefatsi tse sebelisoang ka mafolofolo kalafong ea khatello ea mali,
- Li-inhibitors tsa MAO - lithethefatsi tse thibelang khatello ea kelello tse boletsoeng ho mafu a kelello,
- li-anabolic steroids
- li-beta-blockers tse sa khethang - tse sebelisoang ho phekola mafu a pelo,
- matlapa a molomo bakeng sa kalafo ea hyperglycemia,
- meriana e nang le lithium
- Tetracycline li-antibacterial lithethefatsi, sulfonamides,
- Vithamine B6
- carbonic anhydrase inhibitors - sehlopha sena se kenyelletsa palo e kholo ea lithethefatsi ka phello ea diuretic,
- Clofibrate - e fokotsa bongata ba cholesterol e tlase maling,
- ketoconazole - setlhare se khahlanong le mycoses,
- fenfluramine - sethethefatsi sa ho laola takatso ea lijo,
- bromocriptine - sethethefatsi se sebelisitsoeng gynecology,
- cyclophosphamide - sethethefatsi sa antitumor,
- mebendazole - moriana bakeng sa kalafo ea helminth,
- theophylline ke bronchodilator.
Bakeng sa bakuli ba hlokang kalafo ka meriana ena, ho hlokahala hore ba fokotse tekanyetso ea litokisetso tsa insulin ka nako ea puso ea bona.
Lipheko tse latelang li mpefatsa phello ea Protafan:
- li-blockers tsa liteishene tsa calcium tse butle, ka tsela e 'ngoe lihanyetsi tsa calcium - li sebelisoa kalafong ea khatello ea mali,
- Lihormone tsa qoqotho li sebelisoa e le pheko e ncha
- glucocorticosteroids,
- kutloelo-bohloko
- lithibela-pelehi bakeng sa tsamaiso ea molomo,
- santantantanthuri
- antihypertensive meriana "Clonidine",
- anti-sethoathoa - "Phenytoin",
- nicotinic acid
- nikotine
- heparin
- morphine
- Hormone somatotropin,
- diazoxide e nang le phello e matla le e hlasimollang,
- dinazole - e sebelisetsoa ho phekola endometriosis le maqhubu a mang a tlhaho ea litho tsa botšehali.
Lintho tse ling tsa lithethefatsi le lithethefatsi ka botsona li ka ama khatello ea tsoekere ka mekhoa e fapaneng - ke hore, e ka nyoloha kapa ea fokotseha. Lintho tsena li kenyelletsa joala, reserpine, salicylates.
Ho na le molao-motheo oa mantlha oa ts'ebeliso ea lithethefatsi tsohle tse nang le insulin - kalafo e rarahaneng feela ka mekhoa e amohelehang, tumellano ea eona e tiisitsoeng ka molao ke lithuto tse khethehileng tsa bongaka.
Hoo e ka bang tafole e phethahetseng ea Protafan e hlahisoa ka har'a tafole. Phapang ea bona e ka theko le moqapi feela.
Lebitso la moriana | Moetsi | Theko |
"Humulin NPH" | USA | Ke li-ruble tse ka bang 600. |
Insuman Bazal | France | Hoo e ka bang 1300 rub. |
"Biosulin N" | Russia | Ke li-ruble tse ka bang 500. |
Rinsulin NPH | Russia | Hoo e ka bang li-ruble tse 450. |
Ho tloha ponong ea mahlale a bongaka, ha u fetola "Protafan" ho e-na le ntho e tšoanang e sebetsang, sena ha se nkoe e le phetoho ea mofuta o mong oa insulin. Le lengolo le fanoang ha le supe lebitso la khoebo la moriana, empa karolo ea lona e sebetsang. Empa, ha e le hantle, phetisetso e joalo e ka baka litlamorao tse mpe, taolo e mpe ea glycemic, e hloka phetoho ea litekanyetso le ho baka hypersensitivity. Ha tekanyo ea hemoglobin ea glycated e le ntho e tloaelehileng, 'me tlhaselo ea hypoglycemia e sa etsahale kapa e sa hlahe hangata, ha ho kgothaletswe ho tlohela kalafo le Protafan.
"Protafan" ke tokisetso e matla ea insulin, ka litekanyetso o hloka ho ba hlokolosi hore o se tsose tlhaselo ea hypoglycemia. Ke ne ke laetsoe lilemo tse 'maloa tse fetileng, mme kamora ho ba le khetla ea pele feela tlhaselo e joalo e etsahetse. Kamora ho fetola tekanyetso, ntho e ngoe le e ngoe e ne e lokile, tsoekere e tloaelehile.
Ke sebelisa Protafan hammoho le Actrapid. Ke khotsofetse ke phello, tsoekere e bile ntho e tloaelehileng nako e telele, ho ne ho sena liphoso.
Setlhare se tlameha ho bolokoa se sa fihlelle ngoana. Lifekthering tsa Protafan u ka li reka ka tieo ho latela lengolo la ngaka. Litsenyehelo tse tloaelehileng tsa li-ruble tse 400. bakeng sa botlolo e le 'ngoe le 800 - 1000 bakeng sa li-cartridge.
Qeto
Setlhare se sebelisoa ka mafolofolo merero e fapaneng ea kalafo ea lefu la tsoekere mellitus, eo, ehlile, e netefatsang hore e sebetsa. Ho ba le phello e molemo boiketlong ba lefu la tsoekere. Lingaka le bakuli maemong a mangata ba bua hantle ka Protafan. E u lumella ho boloka tloaelo ea tsoekere maling le ho thibela mathata a lefu lena, ha feela u khetha khetho e nepahetseng ea mofuta oa kalafo.