Mokhoa oa ho sebelisa Metformin Canon?

Setlhare se fumaneha ka mokhoa oa matlapa a koahetsoeng ka filimi. Ho na le matlapa a nang le 500 mg, 850 mg le 1000 mg ea metformin.

Litafole tse nang le litekanyetso tsa 500 mg li potoloha, 'me matlapa a na le litekanyetso tsa 850 mg le 1000 mg (Metformin bolelele) ha a otlolohile.

Setlhare se fumaneha ka mokhoa oa matlapa a koahetsoeng ka filimi.

1. Metformin hydrochloride.
2. Polyethylene glycol (macrogol).
3. Povidone.
4. Talc.
5. Sodium stearyl fumarate.
6. Sodium carboxymethyl starch.
7. Setlolo sa pregelatinized.
8. Opadry II e tšoeu (ho emisoa ho emisang filimi).
9. Tekanyetso ea titanium.
10. Tai ea Polyvinyl.

Ketso ea pharmacological

Metformin e thibela gluconeogeneis, mofuta oa mafura a mahala, hammoho le lits'ebetso tsa lipolysis (ho senyeha hoa mafura) le oxidation ea mafura. Ka nako e ts'oanang, ts'ebeliso ea tsoekere maling e eketsoa ke ho eketsa kutloisiso ea lisele ho insulin.

Setlhare sena se tloaela se ka moriring oa triglycerides le cholesterol maling. Ho fokotseha butle butle ka boima ba bakuli ba batenya.

Moriana o khothalletsoa boteng ba thrombosis, kaha e na le phello ea fibrinolytic. Metformin e thusa ho tlosa mali a mangata methapong ea mali.

Moriana o khothalletsoa boteng ba thrombosis, kaha e na le phello ea fibrinolytic.

Mofumahali

Ha ho nooa ka molomo, sethethefatsi sena se kenngoa butle-butle ka setsing sa ho silila. Ho amoheloa ha Metformin ke 50%. Bioavailability ha e fetang 60%. Ntho ena e fihla sehlohlolong ka plasma nakong ea lihora tse 2-2,5.

Metformin e tlama ka matla le albin ea mali, empa e kenella ka potlako maro a tlhaho. E ntšoa 'meleng ke liphio haholo-holo tse sa fetoheng. Nako ea Excretion ke lihora tse 8-12.

E behiloe bakeng sa eng?

Setlhare sena se laeloa batho ba baholo le bana ba ka holimo ho lilemo tse 10 ho tloha botenya le mofuta oa "lefu la tsoekere" la 2 lefu la tsoekere. Moriana o ka sebelisoa ka mekhoa ea mantlha le ea bobeli (hammoho le insulin).

Matšoao a mang a sebelisitsoeng ke:

1. Fatty hepatosis (sebete dystrophy). Lefu leo ​​ho lona phetoho ea hepatocytes (lisele tsa sebete) ho lithane tsa lipid e bang teng.
2. Ovary ea polycystic. Hangata Psychology ena e tsamaisana le ho hanyetsa insulin. Ho hlahisoa ha hormone ena ka bongata le ho eketseha ha tsoekere ea mali hoa etsahala.
3. Hyperlipidemia Lefu lena le tšoauoa ka litaba tse phahameng tsa lipids le lipoprotein maling.

Pontšo ea tšebeliso ke mafura a hepatosis.

Contraindication

Lithethefatsi li kopantsoe maemong a latelang:

• mamello ea motho ka mong ho ea metformin kapa e thoholetsoeng,
• lefu la tsoekere
• lefu la tsoekere,
• lefu le matla la sebete
• mosebetsi o sa sebetseng oa renal,
• letšollo le matla kapa ho hlatsa,
• mafu a tšoaetsanoang haholo
• hypoxia
• feberu
• sepsis
• anaphylactic makala,
• myocardial infarction
• phefumoloho kapa ho nyekeloa ke pelo,
• bokhoba ba joala
• lactic acidosis,
• khaello ea khalori
• lilemo tsa bana ho fihlela lilemo tse 10.

Ho nka moriana oa lefu la tsoekere

Tumellanong le litaelo, batho ba baholo ba nang le monotherapy ba fuoa 1000-1500 mg ea moriana ka letsatsi. Haeba ho hlokahala, tekanyetso ea letsatsi le letsatsi e eketseha butle-butle ho 2000 mg. Sekhahla se phahameng sa letsatsi ke 3000 mg ea metformin. Tekanyetso ea letsatsi le letsatsi e ka aroloa ka litekanyetso tse 2-3.

Ha e kopantsoe le insulin, tekanyo ea Metformin ke 1000-1500 mg ka letsatsi. Nakong ea kalafo, ho ka hlokahala phetoho ea tekanyetso ea insulin.

U ka e nka joang bakeng sa ho theola boima ba 'mele?

Bakeng sa kalafo ea botenya, sesosa sa eona ke ho hana insulin, moriana o beoa tekanyetso ea pele ea 500 mg hang. Tekanyetso e eketsoa ho 2000 mg ka letsatsi, e eketsa 500 mg ka beke.

Metformin e thusa ho theola boima ba 'mele ha e kopantsoe le phepo e nepahetseng.

Metformin e thusa ho theola boima ba 'mele ha e kopantsoe le phepo e nepahetseng. Empa lijo tse thata li ke ke tsa khomareloa ka lebaka la kotsi ea hypoglycemia.

Ho tloha ka lehlakoreng la metabolism

Kameho ea metabolism:

• lactic acidosis,
• B12 e haella (digestibility) e nang le phepo e nepahetseng.

Litaelo tse khethehileng

Pele ho ts'ebetso le litlhahlobo ho sebelisa lintho tsa radiopaque, meriana e hlakotsoe. Ho tlosa lithethefatsi ho etsoa matsatsi a 2 pele ho tlhahlobo ebe o tsoela pele ka mor'a matsatsi a mabeli.

Pele u buuoa, meriana e felisitsoe.

Sebelisa nakong ea bokhachane le pelehi

Kaha ntho e sebetsang e feta ka har'a placenta, basali ba baimana ha ba khothalletsoe ho nka sethethefatsi sena. Lithuto tse tšepahalang tsa litlamorao tsa metformin ha li so etsoa. Ka linako tse ling lingaka li fa basali baimana meriana ena ha ho hlokahala.

Ho anyesa nakong ea kalafo ho khothalletsoa ho emisa.

Sebelisa bakeng sa ts'ebetso ea renal e senyehileng

Ho sebelisana le lithethefatsi tse ling

Moriana o nooa ka hloko ka litlhare tse latelang:

1. Danazole (moemeli oa hyperglycemic).
2. Chlorpromazine.
3. Li-antipsychotic.
4. Mehloli ea sulfonylureas.
5. NSAIDs.
6. Oxytetracycline.
7. Li-inhibitors tsa ACE le MAO.
8. Clofibrate.
9. Lithethefatsi tsa Hormonal (ho kenyeletsa lithibela-pelehi tsa molomo).
10. Diuretics (ho tloha sehlopheng sa thiazide kapa loop diuretics).
11. Liphetho tsa nicotinic acid le phenothiazine.
12. Glucagon.
13. Cimetidine.

Haeba metsoako e joalo e hlokahala, ngaka e fetola lethal dose la lithethefatsi mme e laola ho kenella ha tsoekere le lactic acid maling.

Ho tsamaisana le joala

Sehlahisoa sena ha se tsamaisane hantle le joala. Joala bo eketsa kotsi ea ho ba le tishu hypoxia, lactic acidosis le litlamorao tse ling.

Lintho tse tummeng tsa sehlahisoa sena li kenyelletsa Glucophage (Merck Sante, France), Formetin (Pharmstandard, Russia), Siofor (Berlin-Chemie, France). Lithethefatsi tsena li na le ntho e tšoanang e sebetsang - metformin hydrochloride.

Meriana e kang Metformin Teva le Metformin Richter ke li-genetic. Li tšoana hantle le Metformin Canon ka sebopeho le ketso, empa li hlahisoa ke bahlahisi ba bang.

Tlhahlobo ho Metformin Canon

Konstantin, ea lilemo li 42, St. Petersburg

Ke qetile lilemo tse fetang 10 ke sebetsa ke le setsebi sa endocrinologist. Setlhare sena se laetsoe bakuli ba nang le lefu la tsoekere le botenya. E thusa ho nolofatsa boemo ba metabolism le tsoekere ea mali. Ke ne ke bona ka seoelo litla-morao tsa ka.

Irina, ea lilemo tse 35, Krasnodar

Metformin ke moemeli ea nepahetseng oa hypoglycemic kalafo ea lefu la tsoekere la mofuta oa 2. Bakuli ba ka ba mamella lipilisi tsena hantle. Kamora khoeli ea ho nka marotholi a tsoekere ea mali. Ho qoba ho opeloa ke mala, ke khothaletsa ho se noe moriana ka mpeng.

Valentine, ea lilemo li 56, Belorechensk

Ke ithutile ka lithethefatsi tse kang Metformin, Siofor, Glucofage ho tsoa ho endocrinologist. O ba khothalelitse ho loants'a lefu la tsoekere. Monyetla oa Metformin ha o bapisoa le analogues ke theko e tlase. Moriana o thusitse mme o sa ka oa baka litlamorao.

Alexander, ea lilemo li 43, Volgograd

Ke noa sethethefatsi sena ho thibela lefu la tsoekere. Tsoekere ea mali e ile ea qala ho phahama, mme ngaka ea laela Metformin. Ha kea fumana litlamorao tse mpe nakong ea phekolo.

Ekaterina, ea lilemo tse 27, Moscow

Kamora ho beleha, ke ile ka qala ho fola kapele. Ha ke na ho latela lijo tse thata ka nako e telele, ka hona ke nkile qeto ea ho leka Metformin ho fokotsa takatso ea lijo. Moriana o thusitse ho tlosa likhilone tse 5 ka khoeli. Ke tlala thaka ebile ha ke khone ho e ja ka bongata.