Cardiomagnyl: litaelo tsa tšebeliso

Lithethefatsi Cardiomagnyl ke moemeli oa sehlopha sa bongaka le sa lithethefatsi sa li-antiplatelet agents tsa lithethefatsi. E sebelisoa ho thibela thrombosis ho li-pathologies tse fapaneng tsa tsamaiso ea methapo ea pelo.

Sokolla foromo le sebopeho

Cardiomagnyl e fumaneha ka mokhoa oa matlapa, matlapa a koahetsoeng ka har'a tsamaiso ea molomo (tsamaiso ea molomo). Li kenyelletsa lintho tse peli tse sebetsang - acetylsalicylic acid 75 kapa 150 mg le magnesium hydroxide 15.2 kapa 30,9 mg ho le letlapa le le leng. Letlapa le na le likarolo tse thusang, tse kenyeletsang:

Litapole le starch ea poone.
Magnesium stearate.
Hypromellose.
Seluloele sa ka-Mycrystalline.
Talc.
Propylene glycol.

Matlapa a na le 'mala o mosoeu ka' mala, sebopeho sa ona se ngotsoe ka sebopeho sa pelo. Li tšetse ka botlolong ea khalase e lefifi. Pakete e le 'ngoe ea karete e na le botlolo e nang le matlapa le litaelo tsa ho sebelisa lithethefatsi.

Ketso ea pharmacological

Acetylsalicylic acid, eo e leng karolo ea lithethefatsi, ke sethethefatsi se seng khahlanong le ho tsoa mali se se nang mali. E inhibits (inhibits) ea enzyme cycloo oxygenase (COX 1 le 2), e thusang ho fetoloa ha arachidonic acid ho prostaglandins. Li-Prostaglandins, ntle le ts'usumetso ea ho ruruha, le tsona li nka karolo ho kopaneng ea liplatele (gluing) nakong ea ho etsoa ha methapo ea methapo ea methapo. Ka hona, khatello ea COX e lebisa ho fokotseha ha li-prostaglandins le menyetla ea thrombosis. Phello e phahameng ea anti-aggregation e bontšoa ha litekanyetso tsa acetylsalicylic acid e le 75-150 mg, litekanyetso tse phahameng li sebelisoa bakeng sa analgesic, anti-inflammatory athari le mocheso o tlase oa 'mele bakeng sa li-pathologies tse fapaneng tsa ho ruruha.

Magnesium hydroxide e kenyellelitsoe ho motsoako oa lithethefatsi ho fokotsa litlamorao tse mpe tsa acetylsalicylic acid ho membrane ea mucous ea tšilo ea lijo.

Kamora ho nka letlapa la Cardiomagnyl, asiti ea acetylsalicylic e potlakile ebile e batla e kenelletse ka hare ho potoloha ea systemic ho tloha lumen. E ajoa ka ho tšoana liseleng tsohle tsa 'mele' me e tšeloa ka har'a sebete. Lihlahisoa tse sa sebetseng tsa phapanyetsano ea acetylsalicylic acid li tšeloa ka har'a moroto. Bophelo ba halofo (ho felisoa ha halofo ea lethal dose lohle) bo nka lihora tse ka bang 12. Magnesium hydroxide ha e kenngoe tsamaisong ea kemiso, phello ea eona ea meriana e fumanoa ka kotloloho mokhoeng o kaholimo oa tšilo ea lijo.

Cardiomagnyl ke eng?

Matlapa a Cardiomagnyl a bontšoa bakeng sa maemo a fapaneng a pathological, a tsamaeang le kotsi e eketsehang ea intravascular thrombosis:

Angina pectoris e sa tsitsang ke tlolo ea bohlokoa ea phallo ea mali ka pelong e nang le monyetla o moholo oa ho theoleha myocardial infarction (lefu la karolo ea mesifa ea pelo).
Thibelo ea intravascular thrombosis ho lefu la tsoekere, ho nyekeloa ke pelo, botenya, ho tsuba, khatello ea mali le khatello e matla le khatello ea mali ea nakoana le botsofaling.
Thibelo ea khafetsa myocardial infarction kapa intravascular thrombosis.

Setlama se boetse se sebelisetsoa ho thibela thromboembolism (sebopeho sa methapo ea methapo ea methapo le ho sisinyeha ha eona ka morao methapong ka mali le ho phatloha hoa e 'ngoe ea tsona) kamora ho etsa opereishene likepeng, haholo-holo coronary artery bypass grafting (CABG), percutaneous coronary angioplasty.

Contraindication

Ts'ebeliso ea matlapa a Cardiomagnyl e tšoaelitsoe maemong a pathological (haholo-holo maemong a kotsi e kholo ea kholo ea morao ho tsoa mali kapa hemorrhage litho tsa ka hare), e kenyelletsa:

Hemorrhage ka sebopeho sa tsamaiso ea methapo e bohareng, haholo-holo bokong.
Ho tsoa mali ka mpeng.
Tloaelo ea ho ruruha ho tsoa mali ke ho haella ha vithamine K 'meleng, hemorrhagic diathesis, thrombocytopenia.
Erosive-ulcerative pathology ea likarolo tsa tšilo ea lijo, e tšoauoa ka kotsi e kholo ea ho tsoa mali ho tsoa bofokoling ba mucosal, haholoholo mokhatlong oa ho mpefala ha ts'ebetso ea methapo ea methapo.
Khaello ea "glucose-6-phosphate dehydrogenase" e amanang le maemo le tšebetso ea lisele tse khubelu tsa mali.
Tsamaiso e tšoanang ea methotrexate.
Bana ba ka tlase ho lilemo tse 18.
Nako ea kemaro ho I le II trimester ea eona, hammoho le matsoele.
Ho hloleha ho ho phekola ha liphoko.
Bronchial asthma, nts'etsopele ea eona e ts'oaroang ke ts'ebeliso ea lithethefatsi leha e le life tsa sehlopha sa pharmacological, lithethefatsi tse seng khahlanong le ts'oaetso tsa mali.
Ho se mamellane ha motho ka mong ho acetylsalicylic acid, magnesium hydroxide kapa likarolo tse thusang tsa sethethefatsi.

Ka hloko, lithethefatsi li sebelisoa bakeng sa ho hloleha hoa hepatic kapa renal ha bonolo ho leka-lekana, gout, ho ba teng ha khoholeho kapa leqeba la ka mpeng ea ho ikoahlaea (ntlafatso ea bongaka le laboratori), "aspirin triad" (lefu la bronchial asthma, polyposis ea tsebe, "assirin"). trimester. Pele o qala ho nka matlapa a Cardiomagnyl, o lokela ho etsa bonnete ba hore ha ho na li-contraindication.

Tekanyetso le tsamaiso

Matlapa a Cardiomagnyl a nooa ka molomo ka kakaretso, ha a phuthoe le ho hlatsuoa ka metsi a lekaneng. Bakeng sa thibelo ea mantlha ea thrombosis e nang le lefu la pelo, litekanyetso tsa moriana ke 75 mg 1 nako e le ngoe ka letsatsi, ha pilata e sebelisoa hangata mantsiboea ka 19,00, nako ea kalafo e nka bophelo bohle. Haeba ho hlokahala ho thibela nts'etsopele ea infrction ea myocardial e phetoang, ka angina e sa tsitsang, tekanyo e fapana pakeng tsa 75-150 mg ka letsatsi. Motsoako o tšoanang o sebelisoa ho thibela thrombosis kamora ho buuoa likepeng. Ngaka e beha nako ea kalafo ka bonngoe.

Litlamorao

Ho nka matlapa a Cardiomagnyl ho ka lebisa ho hola hoa litlamorao tse mpe tse tsoang ho litho tse fapaneng le litsamaiso, li kenyeletsa:

Sistimi ya tshilo ya mmele - pelo e opa haholo hangata e ba teng, hangata ho ka ba le ho nyekeloa, ho hlatsa, bohloko ba ka mpeng ka ho kenella kahara mpa ka mpeng, ho etsoa ha liso kapa ho senyeha hoa tšilo ea lijo tse kaholimo. Ho hlalosoa maemo a ikhethileng a ho tlotsa (ho etsoa ka lesoba ka mpeng) kapa leqeba la mokokotlo, colitis (ho ruruha ha mala a maholo), lefu le sa foleng la bowel ha o ntse o sebelisa moriana.
Ts'ebetso ea methapo - hlooho e opang, ho tsekela nako le nako, ho otsela kapa ho hloka boroko, tinnitus, ka seoelo ho ka ba le ho ruruha ha methapo.
Sisteme ea phefumoloho ke bronchospasm (e fokotsang lumen ea bronchi ka lebaka la keketseho e kholo ea molumo oa mesifa e boreleli ea mabota a eona).
Moko oa masapo o mofubelu le tsamaiso ea mali - ho tsoa mali ho eketsehileng ka lebaka la ho se lekane hoa liplatelete, phokolo ea mali e sa tloaelehang. Ka seoelo, ho fokotseha hoa palo ea liplatelete (thrombocytopenia) le neutrophils (neutropenia) lia hlaha.
Litla-morao tsa maemo a ho haroha letsoalo - linyeoe tsa ntlafatso ea angioedema Quincke edema (plasma e tsoa ka har'a ntho ea methapo ea sefahleho le litho tsa ka ntle tsa setho sa botšehali), hangata ho sisinyeha ha anaphylactic (ho teba ha systemic allergic ka ho fokotseha hoa khatello ea mali le nts'etsopele ea ho hloleha ha litho tse ngata) hangata ho hlalosoa.

Ntshetsopele ea litlamorao kamora ho nka matlapa a Cardiomagnyl ke motheo oa ho tlosoa hoa lithethefatsi.

Litaelo tse khethehileng

Pele o qala ho nka matlapa a Cardiomagnyl, o lokela ho bala litaelo tsa sethethefatsi ka hloko, etsa bonnete ba hore ha ho na li-contraindication. U lokela ho ela hloko litaelo tse 'maloa tse ikhethang, tse kenyeletsang:

Ho nka matlapa a Cardiomagnyl ho ka baka tlhaselo ea asthma ea bronchial, haholo haeba e etsahetse ho mokuli nakong e fetileng.
Pele ho ts'ebetso e reriloeng ea ho buoa, setlhare se ka tloheloa matsatsi a 'maloa, se amanang le thibelo ea ho tsoa mali.
Ho kopana ha tšebeliso ea lithethefatsi le lithethefatsi tse ling tsa sehlopha sa bongaka-meriana, li-antiplatelet agents le li-anticoagulants (ho thibela ho bolaoa ha mali) ho eketsa haholo menyetla ea kholo ea morao ho tsoa mali.
Acetylsalicylic acid e ka tsosa nts'etsopele ea gout ho batho ba nang le acid e felileng ea uric acid.
Ho kopana ha matlapa a Cardiomagnyl a nang le methotrexate ho eketsa kotsi ea litlamorao ho tsoa maling le tsamaisong ea mali.
Ts'ebeliso e ts'oanang ea li-glucocorticosteroids e fokotsa boemo ba acetylsalicylic acid 'meleng, ka hona, kamora ho hlakoloa ha bona, ho ka ba le overdose ea acetylsalicylic acid.
Tekanyetso e phahameng ea lithethefatsi e ka baka kholo ea hypoglycemia (ho fokotseha ha tsoekere ea mali), eo ho bohlokoa ho e nka ho batho ba nang le khaello ea phepo ea carbohydrate metabolism (lefu la tsoekere).
Ha ho kgothaletswe ho nwa joala nakong ea kalafo le moriana, kaha sena se eketsa kotsi ea ho tsoa mali.
Motsoako oa ho nka litafole tsa Cardiomagnyl ka ibuprofen ha oa kenyelletsoa ka lebaka la kotsi e eketsehileng ea ho ba le mathata a mangata a pelo.
Setlhare ha se ame ts'ebetso ea ts'ebetso ea "cortex" e sebetsang ka kotloloho, empa mabapi le nts'etsopele ea mathata, tlhokomeliso e lokela ho sebelisoa nakong ea ts'ebetso ea mosebetsi e hlokang tlhokomelo e eketsehileng le lebelo la maikutlo a psychomotor.

Ka marang-rang a lipilisi, matlapa a Cardiomagnyl a hasoa ntle le taelo ea ngaka. Leha ho le joalo, ha ho khothalletsoe ho qala ts'ebeliso ea bona ntle le taelo e loketseng ea ngaka.

Matšoao angiocardil

Phekolo e rarahaneng ea lefu la pelo (corina ea pelo) (Angina pectoris, infraction ea myocardial), ho nyekeloa ke pelo ho sa foleng, cardialgia khahlano le semelo sa dishormonal cardiomyopathy.

Mo kalafong e rarahaneng ea likotsi tsa cerebrovascular (ischemic stroke, ho haella ha cerebrovascular).

Ts'ebetso e fokotsehileng, khatello ea kelello le 'mele tse ngata (ho kenyeletsoa le har'a baatlelete).

Alcoholatula ea ho tlohela joala (hammoho le kalafo e khethehileng ea joala).

E le karolo ea phekolo e rarahaneng ea hemophthalmus le retinal hemorrhage ea etiology tse fapaneng, thrombosis ea methapo e kholo ea methapo ea methapo le makala a eona, retinopathies ea etiologies tse fapaneng (diabetesic, hypertension).

Ts'ebeliso ea angiocardil nakong ea kemaro le lactation

E kopantsoe le moimana. Ka nako ea kalafo o lokela ho emisa ho anyesa.

Angiocardyl ke moemeli oa metabolic.

Meldonium ke analogue ea sebopeho sa gamma-butyrobetaine - ntho e fumanoang seleng e 'ngoe le e' ngoe ea 'mele oa motho.

E sitisa gamma-butyrobetaine hydroxylase, e fokotsa ho hlophisoa ha carnitine le ho tsamaisoa ha mafura a mangata a ketane ka li-membrane tsa sele, mme e thibela ho bokellwa ha mefuta ea ts'ebetso ea li-acid tse tsoang ho acid, li-derivatives tsa acylcarnitine le acylcoenzyme A ka liseleng ka lebaka la ho fokotseha ha methapo ea methapo. Tabeng ea tšenyo e mpe ea ischemic ho myocardium, e liehisa sebopeho sa tikoloho ea necrotic mme e khutsufatsa nako ea ntlafatso. Bofokoli ba pelo bo sa feleng (CHF), ho mamella ho ikoetlisa hoa eketseha. Ka angina pectoris, khafetsa ea ho ts'oaroa e ea fokotseha. A a hlobaetsang le a sa foleng a ischemic mathata a ho potoloha ha litho tsa mali a mali ho ntlafatsa phallo ea mali ka leihlo la ischemia, le kenya letsoho ho abolleloeng ha mali molemong oa sebaka sa ischemic. E sebetsa hantle maemong a methapo le methapo ea methapo ea methapo ea methapo.

E matlafatsa ts'ebetso ea 'mele, e fokotsa botebo ba matšoao a khatello ea kelello le' mele. E kenya ts'oaetso ea cellular le e tlotlollang. E khaola lipontšo tsa limela tse nang le tahi ho sa feleng le ho itlhahisa.

Bioavailability le intravenous tsamaiso ke 100%. Tlhokahalo e phahameng (C _max ) plasma ea mali e fumanoa hang ka mor'a hore e kenngoe.

Metabolism: metabolized 'meleng le sebopeho sa metabolites tse peli tse kholo tse epolotsoeng ke liphio.

Ho tlohela: halofo ea bophelo (TU.) ke lihora tse 3-6.

Litla-morao tsa angiocardyl

Ho tsoa ho tsamaiso ea pelo le pelo: ka seoelo - tachycardia, ho fokotseha kapa keketseho ea khatello ea mali.

Ho tsoa ho tsamaiso ea methapo e bohareng: ka seoelo - psychomotor furu, ho hloka boroko.

Ho tsoa ts'ebetsong ea tšilo ea lijo: ka seoelo - mathata a dyspeptic

Litla-morao: ka seoelo - ho hlohlona, lekhopho, ho sesa letlalo, angioedema.

Matšoao a laboratori: eosinophilia.

Tse ling: ka seoelo - bofokoli bo akaretsang.

Meldonium ha se lithethefatsi tsa mola oa pele bakeng sa lefu la mokokotlo oa mokokotlo mme ts'ebeliso ea lona ha e hlokehe ka potlako.

Phekolo ea bakuli ba nang le mafu a sebete a sa foleng le a liphio, ho lokela ho sebelisoe tlhokomeliso, haholoholo ka tšebeliso ea nako e telele ea lithethefatsi.

Matšoao: ho fokotseha ha khatello ea mali, ho tsamaisana le hlooho e opang, tachycardia, kizungu le ho fokola ka kakaretso.

E ntlafatsa phello ea ho fokotseha hoa matla le lithethefatsi tse ling tsa antihypertensive, glycosides ea pelo.

Ka lebaka la nts'etsopele ea tachycardia e itekanetseng le hypotension ea methapo, tlhokomeliso e lokela ho sebelisoa ha e kopantsoe le nitroglycerin, nifedipine, alpha-blockers, lithethefatsi tse thibelang antihypertensive, le li-vasodilators tse potolohang.

E ka kopantsoe le lithethefatsi tsa antianginal, li-anticoagulants, li-antiplatelet agents, lithethefatsi tsa antiarrhythmic, diuretics, bronchodilators.

Sebakeng se lefifi ka mocheso oa 15 ho isa ho 25 ° C. Bophelo ba Shelf ke lilemo tse 2.

Pharmacodynamics le pharmacokinetics

Wikipedia e re acetylsalicylic acid Ke mofuta oa mofuta oa acid e tsoekere ea acetic (ethanoic) mme e na le matla a ho kokobetsa bohloko, ho kokobetsa mocheso le ho fokola, hape e sitisang ho kopanngoa. palo ea liplatelete.

Acetylsalicylic acid (ASA) ka tsela e sa fetoheng e thibela enzyme COX-1, e fella ka ho thibeloa ha mokena-lipakeng oa bohlokoa oa ho kopanya le ho nyenyefatsa palo ea liplatelete TXA-2 le thibelo ea ho kopana palo ea liplatelete.

Ho lumeloa hore ASA e ka thibela ho kopanya palo ea liplatelete le ka mekhoa e meng, ka hona e ka sebelisoa ka bongata bo fapaneng lefu la vascular.

Hydroxide ea magnesium e fumanehang matlapeng e sireletsa mucosa ea tšilo ea lijo hore e se ke ea hlekefetsoa ke ASA.

ASA e ananeloa ho tsoa pampiring ea mala ka bongata bo boholo. T1 / 2 ea ntho ena - metsotso e ka bang 15. Tekanyo ena ea ho felisoa e bakoa ke 'nete ea hore ka plasma ea mali, sebete le mala acetylsalicylic acid ka potlako hydrolyzed ho salicylic (SC).

Bakeng sa salicylic acid T1 / 2 - lihora tse ka bang tharo. Ha lits'ebetso tsa enzyme li khotsofetse, tse hlokomelehang ka nako e tšoanang le tsamaiso ea ASA ka tekanyetso e fetang 3 g, letšoao le ka eketseha haholo.

Bioavailability ea ASA e ka ba 70%. Letšoao le tšoauoa ka phapang e bakoang ke taba ea hore ntho ena e kenngoa ka tlasa hydrolysis e tlasa ts'usumetso ea li-enzyme. Bioavailability ea SC e tsoa ho 80 ho ea ho 100%.

Litekanyetso tsa magnesium hydroxide e sebelisitsoeng ha li ame bioavailability ea ASA.

Mofumahali

ASA e ananeloa ho tsoa mokokotlong oa mokokotlo hoo e ka bang ka botlalo. Bophelo ba halofo ea ASA ke metsotso e 15, hobane ka ho nka karolo ha li-enzymes, ASA e potlakisa hydrolyzed ho salicylic acid (SC) ka mpeng, sebete le plasma ea mali. Bophelo ba halofo ea SC ke lihora tse ka bang 3, empa bo ka eketseha haholo ka taolo e tšoanang ea litekanyetso tse kholo tsa ASA (ho feta 3.0 g) ka lebaka la tsamaiso ea enzyme e ngata.

Bioavailability ea ASA e batla e le 70%, empa boleng bona bo fapana haholo, kaha ASA e feta ka har'a hydrogenysis (mucous membrane ea gastrointestinal, sebete) ho SC tlasa ts'ebetso ea li-enzyme. Bioavailability ea SC ke 80-100%.

Methapo ea magnesium hydroxide e sebelisitsoeng ha e ame bioavailability ea acetylsalicylic acid.

Sebelisa nakong ea bokhachane le nakong ea ho anyesa

Tšebeliso ea litekanyetso tse kholo tsa li-salicylates likhoeling tse 3 tse qalang tsa moimana e amahanngoa le khafetsa khafetsa ea bofokoli ba nts'etsopele ea fetal. Ka trimester ea bobeli ea boimana, li-salicylates li ka fuoa feela ka tlhahlobo e tiileng ea kotsi le molemo.

Khoeling ea ho qetela ea kemaro, li-salicylate ka tekanyetso e phahameng (tse fetang 300 mg / ka letsatsi) li baka tšitiso ea pelehi, ho koaloa kapele ha ductus arteriosus ka popelong, ho eketseha ha mali ho 'm'a le lesea, le tsamaiso hanghang pele ho hlaha li ka baka ho ruruha ha methapo pele ho nako.

Ho khethoa ha li-salicylate ka har'a trimester ea ho qetela ea moimana ho khahlanong le.

Lintlha tse fumanehang tsa kliniki ha lia lekana ho hlahisa monyetla oa monyetla oa ho sebelisa lithethefatsi nakong ea ho anyesa. Pele o fana ka asiti ea acetylsalicylic nakong ea ho anyesa, melemo ea phekolo ea lithethefatsi e lokela ho hlahlojoa ho latela kotsi e ka bang teng ho masea.

Bongata

Ka tekanyetso e nyane ea kalafo e khothalletsoang ea matlapa a Cardiomagnyl, tinnitus e nts'etsapele, ho nyekeloa, ho nyekeloa, ho tsekela le ho ferekana ho ka hlaha. Phekolo ea overdose e joalo e kenyelletsa ho hlatsoa mala, mala, ts'ebeliso ea mala a ka mpeng (k'habone e kenelletseng) le kalafo ea matšoao. Tekanyo e kholo ea tekanyetso (overdose e matla) e ka lebisa ho eketseha ha mocheso oa 'mele (feberu), ho phefumoloha ho eketsehileng (hyperventilation ea matšoafo), e lebisang nts'etsopele ea alkalosis (reaction ea mali ea alkaline) ka tlolo ea molao e boletsoeng ea tlolo ea tšebetso ea tšebetso ea methapo e bohareng ea methapo le pelo. Maemong ana, ho kena sepetlele ka tšohanyetso ho etsoa sepetlele le kalafo sebakeng sa tlhokomelo e matla.

Aspecard, Aspirin Cardio, Acecor Cardio, Reocard, Polokard lia tšoana mabapi le ntho e sebetsang le phello ea kliniki le ea kalafo bakeng sa matlapa a Cardiomagnyl.

Fomu ea tokollo, sebopeho

Angiocardyl e fumaneha ka mokhoa oa tharollo e se nang mebala e hlakileng ea ente. E tšeloa ka har'a ampoules e nang le matla a li-milliliters tse 5. Ka pakete e le 'ngoe ea karete e ka ba le 5 kapa 10 ea ampoules tse joalo.

Tharollo ea millilita e le 'ngoe e na le li-milligram tse 100 tsa meldonium dihydrate e qhibilihileng ka metsing bakeng sa ente.

Ho sebelisana le lithethefatsi tse ling

Ha e sebelisoa ka mokhoa o tšoanang le ho fokotseha hoa methapo ea kutlo le lithethefatsi tse ling ho theola khatello ea mali, hammoho le glycosides ea pelo, Angiocardyl e ka etsa hore matla a bona a be matla le ho feta.

Ka tsamaiso e ts'oanang ea angiocardil e nang le nifedipine, nitroglycerin, vasodilators tsa peripheral, lithethefatsi ho theola khatello ea mali le li-alpha-blockers, arterial hypotension le tachycardia e nyane e ka hlaha.

Moriana o sa tsoa boleloa o ka nooa ntle le tšabo ka ho tšoana le lingaka tsa bronchodilator, meriana ea antianginal, li-antiplatelet, anticoagulants, diuretics le antiarrhythmic drug.

Lipehelo le maemo a polokelo

Angiocardyl e tlameha ho bolokoa bana ba sa e fihle le ho e sirelletsa ka mokhoa o sireletsehileng letsatsing le futhumetseng ka mocheso oa likhato tse 15 ho isa ho 25 tsa Celsius.

Bophelo ba lishelefo tsa moriana ona ke lilemo tse peli. Kamora nako ena, o ke ke oa sebelisa Angiocardil.

Lifekthering tse fumanehang 'Musong oa Russia, theko e tloaelehileng ea lithethefatsi tse kaholimo ke li-ruble tse 220.

Lifekthering tse fumanehang UkraineAngiocardyl ha e rekisoe hajoale.

Lithethefatsi tse latelang li ka bitsoa li-analogues tsa angiocardil:

Boholo ba bakuli ba arabela hantle ho angiocardil. Haeba o khahliloe ke maikutlo a batho ba 'nete ka lithethefatsi tsena, joale u ka li fumana qetellong ea sengoloa.

Qeto

Angiocardyl ke lithethefatsi tse sebelisoang kalafo e rarahaneng ea maloetse a pelo le maloetse a mang.

Setlhare sena se ka sebelisoa ho ophthalmology le meriana ea lipapali.

Angiocardyl e hlahisoa e le ente.

E ka nkuoa kahare, ka intramuscularly le parabulbarno.

Motsoako o ka sehloohong oa motsoako ona ke meldonium.

Ts'ebeliso ea angiocardyl ka linako tse ling e ka baka litlamorao, hammoho le karabelo ea mafu.

Ho na le li-contraindication bakeng sa ho nka angiocardil.

Bana, hammoho le basali ba baimana le ba anyesang, ha ba khothalletsoe ho sebelisa lithethefatsi tsena.

Ho na le lithethefatsi tse ka bitsoang li-analogues tsa angiocardyl.

Sebelisa lithethefatsi tsena feela ka mor'a ho buisana le ngaka.

Angiocardil, litaelo tsa tšebeliso: mokhoa le litekanyetso

Angiocardyl e tsamaisoa ka methapo (i / v), intramuscularly (i / m) kapa parabulbar. Kaha sethethefatsi se ka hlahisa phello e khahlisang, ho khothalletsoa ho e sebelisa hoseng.

Tsela ea tsamaiso ea tharollo, tekanyetso le nako ea kalafo li beoa ka bonngoe, ho latela lipontšo, botebo ba boemo le lintho tse ling.

Mokhoa o khothalelitsoeng oa litekanyetso tsa angiocardyl (e le karolo ea kalafo e kopaneng):

infraction ea myocardial: 500-1000 mg (5-10 ml ea tharollo) iv ka methapo, nako e le 1 ka letsatsi kapa e arotsoe ka ente tse peli, e lateloe ke phetoho ho tsamaiso ea molomo ea meldonium,
angina pectoris, CHF e tsamaeang le li -ormorm Cardiomyopathy Cardialgia: 500-1000 mg (5-1 ml) i.v. ka molapo, nako e le 1 ka letsatsi kapa e arotsoe ka tsamaiso ea 2, kapa 500 mg i / m ka makhetlo a 1-2 ka letsatsi, thupelo ke matsatsi a 10-14, ka phetoho e latelang ea ho nka mefuta ea molomo oa meldonium, thupelo ka kakaretso ke matsatsi a 28-25,
kotsi eaCrebrovascular (karolo e mpe le e sa foleng ea ho fokola ha methapo ea methapo): 500 mg (5 ml) iv kapa ho feta moo ka lebaka la ho haelloa ke phepo e sa foleng - i / m, nako e 1 ka letsatsi bakeng sa matsatsi a 10, e lateloe ke tsamaiso ea molomo, kakaretso - Matsatsi a 28–42, ka khothaletso ea ngaka e eang ka mokhoa o sa foleng, ho ka etsahala hore o tsamaise lithuto tse phetoa makhetlo a 2-3 ka selemo,
lefu la ho itlopa joala: 500 mg (5 ml) IV kapa IM makhetlo a 2 ka letsatsi, nete - matsatsi a 7,7,
retinal hemorrhages le hemophthalmus ea etiology tse fapaneng, retinopathy, thrombosis ea methapo e kholo ea methapo ea methapo le makala a eona: 50 mg (0.5 ml) parabulbarno, nete - matsatsi a 10,
khatello e matla ea 'mele le kelello: 500 mg iv kapa IM hang ka letsatsi, nete - matsatsi a 10-14, haeba ho hlokahala, kamora matsatsi a 14-21, nete ea bobeli e ka etsahala.

Cardiomagnyl kapa Thrombital, ke eng e betere?

Meriana ke lipapatso tse felletseng 'me e sebelisetsoa matšoao a tšoanang. E hlahisoa ke bahlahisi ba fapaneng. Cardiomagnyl ke lithethefatsi tsa Japane, k'hamphani e na le limela naheng ea Denmark, Jeremane, Russia, Trombital ke pheko ea lapeng.

sethethefatsi sa pele
lipakete tse fapaneng le litekanyetso,
nako e telele 'marakeng oa Russia,
botumo bo boholo
matlapa a fapaneng a tekanyetso ea mefuta e fapaneng e u lumellang hore u se ke oa li kopanya.
ho na le meriana e 'ngoe le e' ngoe
theko - ho tloha li-ruble tse 130.

lipakete tse fapaneng le litekanyetso,
ponahalo ea sephutheloana ka mebala e fapaneng bakeng sa litekanyetso tse fapaneng,
theko - ho tloha li-ruble tse 120.

hoo e batlang e le ponahalo e ts'oanang ea liphutheloana tsa litekanyetso tse fapaneng,
ka mor'a hore ba qale ho hlahisa Russia, batho ba bang ba ile ba e lahla.

letsatsi la ho felloa ke nako le nyane
ho se tšepe bakuli ka lebaka la lebitso le lecha,
ha ho na likotsi tse arohanyang,
eseng litlhare tsohle
lipilisi tsohle li shebahala li ts'oana.

Cardiomagnyl kapa Thrombo Ass, ke eng e betere?

Lithethefatsi ke tsa sehlopha se tšoanang sa li-pharmacotherapeutic - li-antiplatelet agents. Moetso o kenyelletsa acetylsalicylic acid (ASA), magnesium hydroxide e kenyelletsoa ho Cardiomagnyl. Li na le matšoao a tšoanang, li sebelisoa ho thibela infarction ea myocardial, stroke, karohano ea mali ka mor'a ho kenella ka ts'ebetso.

lipakete tse fapaneng le litekanyetso,
magnesium e sireletsa mabota a mpa ho tsoa litlamorao tsa ASA,
mefuta e fapaneng ea matlapa a u lumella hore u se ke ua ferekanya litekanyetso.
matlapa a ka aroloa kapa a sithabetsoa,
theko - ho tloha li-ruble tse 130.

lipakete tse fapaneng le litekanyetso,
Letlapa le na le motsoako o khethehileng o sireletsang mpa,
Boleng ba Europe
theko - ho tloha ho li-ruble tse 50.

matlapa a arohaneng a ke ke a bolokoa, oxidation ea hlaha mme thepa ea kalafo ea lahleha,
litlamorao tse ling.

matlapa ha a khothalletsoe ho aroloa ka lebaka la khetla,
u ke ke oa e nka ka mpeng e se nang letho,
likhothaletso tse ling hape.

Cardiomagnyl kapa Aspirin Cardio, ke eng e betere?

Lithethefatsi tsena li sebelisetsoa ho fokotseha hoa mali, haeba ho na le kotsi ea mokokotlo, bakeng sa thibelo ea mantlha ea mafu a pelo, joalo-joalo Cardiomagnyl ke moemeli oa antiplatelet, 'me Aspirin Cardio ke NSAID.

mefuta e fapaneng ea a paka le a litekanyetso,
tlatsetso ea magnesium bakeng sa ho mamella lithethefatsi ka mpeng,
E lumelloa ho arolelana lipilisi,
matlapa a litekanyetso tse fapaneng a na le libopeho tse fapaneng tsa jiometri, e li lumellang hore li se ke tsa ferekan
theko - ho tloha li-ruble tse 130.

e fumaneha ka litekanyetso tse fapaneng.
matlapa a entsoe ka ente e sirelletsang mpa,
sethethefatsi sa pele
ho baloa haholoanyane
theko - ho tloha 135 li-ruble.

litlamorao tse ling
bophelo bo bokhutšoaane ba raka.

eseng ka linako tsohle litlhare tsa meriana - mathata a phepelo,
e ke ke ea aroloa ka lebaka la khetla
lipakete tsa litekanyetso tse fapaneng li shebahala li tšoana - u ka li kopanya ha u reka,
likhothaletso tse ling hape.

Ho sebelisana le lithethefatsi

vasodilators ea mahlakoreng, li-antihypertensive, lithethefatsi tsa alpha-blocker, nifedipine, nitroglycerin: ponahalo ea tachycardia e sa foleng le ho fokotseha ha khatello ea mali ho ka hlokomeloa, ka ts'ebetso ena ea motsoako, tlhokomelo e lokela ho nkoa
cardiac glycosides, lithethefatsi tse fokotsang letsoalo la mokokotlo, lithethefatsi tse ling tse felisang phello: kalafo ea lithethefatsi tsena e ka matlafatsoa,
lithethefatsi tsa antianginal le antiarrhythmic, li-antiplatelet agents, li-anticoagulants, li-bronchodilators, diuretics: ts'ebeliso e kopaneng ea lithethefatsi tsena ka meldonium e lumelletsoe.

Li-Analogs tsa Angiocardyl ke Meldonium Organika, Idrinol, Meldonium, Vasomag, Meldonium-SOLOpharm, Meldonat-Lekpharm, Meldonium-Eskom, Ripronat VM, Meldonium-Binergia, Meldonium-DECO le ba bang.

Litlhahlobo mabapi le Angiocardil

Litlhahlobo tse 'maloa tsa angiocardyl li ntle haholo. Bakuli ba hlokomela ho sebetsa ha sethethefatsi ha se sebelisoa nakong ea ntlafatso ea postoperative. Liphetho tse ntle li fumanoa ts'ebelisong ea eona kalafong e rarahaneng ea lefu la pelo, ho nyekeloa ke pelo le likotsi tsa pelo, hammoho le nakong ea khatello e matla ea 'mele le kelello. Joalokaha ho totobalitsoe, Angiocardyl e ntlafatsa boemo bo akaretsang, e thusa ho tlosa moea o khuts'oane le ho fokotsa khatello ea mahlaba ka pelong, e eketsa ts'ebetso, e thusa ho eketsa mamello, e ntlafatsa mohopolo.

Litla-morao, ho latela litekolo, ha li na seoelo.

Matlapa a Cardiomagnyl - a tsoa ho eng?

Matšoao Cardiomagnyl:

bohale (myocardial infarction (IM) angina e sa tsitsang) kapa lefu le sa feleng la ischemic,
thibelo ea mantlha ea mafu a CVD ho bakuli ba kotsing (ba nang le botenya, lefu la tsoekere, khatello ea kelello ea methapo, hypercholesterolemia, hammoho le ho ba le nalane ea malapa ea matšoao a myocardial infarctionka tlase ho lilemo tse 55)
thibelo ea mantlha a hlobaetsang le venous thrombosis le thibelo ea lithuto tse ncha mali (thibelo ea bobeli ea thrombosis).

Contraindication Cardiomagnyl

Lits'ebetso tse latelang tsa litlolo tsa moriana li thathamisitsoe ho semelo:

hypersensitivity ho ASA, salicylates tse ling,
mamello ho likarolo leha e le life tse thusang tsa matlapa,
halefisitsoe uleptic ulcer,
tšollo ea mali (hemophilia,thrombocytopeniaho hloleha vithamine K),
ho hlobaela ho matla (ka GFR ka tlase ho 10 ml ka motsotso) kapa ho hloleha ha meno,
ho khutla hoa pelo ha pelo,
tsosoa ke ts'ebeliso ea li-NSAIDs / salicylates Edema ea Quincke kapa asthma ea bronchial ho anamnesis,
lilemo tsa bana
trimester ea ho qetela ea boimana
kamohelo e tšoanang methotrexate ka tekanyetso e fetang 15 mg / beke.

Litaelo tsa ho sebelisa Cardiomagnyl

Ka lefu la pelo ea coronary (ka tsela efe kapa efe), lethal dose ea ho qala ke 150 mg / ka letsatsi. Ka kalafo ea tlhokomelo, ho fanoa ka tekanyo ea halofo.

E sa tsitsa angina pectoris/ MI ea hlobaetsang, litekanyetso li nepahetse ho tloha ho tse 150 ho isa ho 450 mg / ka letsatsi kalafo e lokela ho qala kapele ka mor'a ho qala matšoao.

Mokhoa oa ho nka cardiomagnyl bakeng sa thibelo?

Ho thibela thuto hape mali mehatong ea pele ea kalafo, mokuli o fuoa 150, nakong e tlang - 75 mg / letsatsi.

Pilisi ea Prophylactic ho thibela CVD (k.j. acute coronary syndrome) le thrombosis - 75 mg / letsatsi.

Nka nka moriana ho fihlela neng?

Nako ea ts'ebetso e itšetlehile ka likarolo tsa lefu le boima ba lefu lena.

Maemong a mang (ho ea ka lipontšo, ho nka li-contraindication le ho beha nako le nako tlhahlobo ea khatello ea mali le mali), moriana o ka fuoa bophelo bohle.

Nako e kae ea ho sebelisa moriana e ka khethoang feela ke ngaka e eang.

Ke eng e ka nkang Cardiomagnyl?

Analogs Cardiomagnyl ho latela khoutu ea ATC, sebopeho sa lintho tse sebetsang le foromo ea tokollo: Acard, Asacil-A, Aspeter, Aspirin Cardio, Acetylsalicylic acid, Magnikor, Thrombo ACC, Thrombolic Cardio, Thrombogard, Ecorin.

Analogues ea moriana o nang le ts'ebetso e haufi: Avix, Agrenox, Aspigrel, Brilinta, Vazotik, Monofram, Deplatt, Sylt, Ipaton, Clopidogrel, Clopile, Lopigrol, Miogrel, Plavigrel, Plavix, Li-trombeks, Kameho.

Theko ea li-analogu tsa Cardiomagnyl e tsoa ho li-ruble tse 8.

Ke efe e betere: Cardiomagnyl kapa Thromboass?

Matlapa a Thrombo ACC ke NSAID e sebelisetsoang ho thibela stroke, lefu la pelo, vein thrombosis e tebileng, thromboembolism le maemo a mang a pathological. Motheo oa moriana ke acetylsalicylic acid.

Molao-motheo oa ts'ebetso ea Cardiomagnyl le analogue ea eona e thehiloe ho bokhoni ba ASA ho thibela motsoako oa thromboxane le Pg, e thusang ho fokotsa kakaretso le khokahano palo ea liplateletehammoho le ho fokotsa ho ruruha.

Ntle le moo, lithethefatsi ka bobeli li fokotsa litaba tsa ho kopants'oa ke K-ho eketsa mesebetsi ea plasma.

Phapang e kholo ea Cardiomagnyl ho tloha sebakeng sa eona: sebopeho le mofuta oa tokollo. Matlapa a Thrombo ACC a na le 50 kapa 100 mg ea ASA, mme magnesium hydroxide ha e eo. Ho fokotsa litlamorao tse mpe tsa ASA, matlapa a entsoe ka koae e khethehileng e sirelletsang e ka kenngoang habonolo kahare.

Bakuli ba siea litlhahlobo tse tšoanang ka lithethefatsi, empa Thrombo ACC, ka maikutlo a bona a mantlha, e baka karabelo e fokolang.

Acecardol le Cardiomagnyl - phapang

Acecardol Ke setlhare se nang le motsoako o sebetsang hape ke ASA.Phapang ea eona ho Cardiomagnyl ke ho se be teng ha magnesium hydroxide ka sebopeho, sebopeho sa tokollo (matlapa a khetla) le litekanyetso tsa ASA (50/100/300 mg / tab.).

LipilisiAcecardolHo khothalletsoa ho nka 1 r. / Letsatsi. Matlapa a Cardiomagnyl a nooa ka mor'a lijo pele ho lijo.

Ke efe e betere: Cardiomagnyl kapa Aspirin Cardio?

Aspirin Cardio Ke litokisetso tsa mantlha tsa k'hamphani Bayer AG. Sesebelisoa ke sa sehlopha sa litokisetso tsa ASA se nang le bopaki bo boholo ka ho fetisisa. Ka lebaka la membrane e khethehileng ea qhibilihang ea enteric, ntho ea eona e sebetsang ha e lokolloe ka mpeng, empa ka mpeng ea mala, ka hona Aspirin Cardio e mamelloa hantle ke bakuli ho feta ka tloaelo acetylsalicylic acid.

Matlapa a fumaneha ka lipakete tsa khalendara, tse lumellang ho ntlafatsa taolo holim'a kalafo eo mokuli a e laetsoeng ke ngaka.

Cardiomagnyl nakong ea kemolo

Ka trimester ea pele, ho ja litheko tse phahameng tsa salicylates ho amana le keketseho ea tekanyo ea bofokoli nts'etsopeleng ea lesea.

Ka trimester ea bobeli, lithethefatsi tsa sehlopha sena li sebelisoa ho nahanisisa ka kalafo eo 'mele oa' m'a le menyetla e ka bang le eona ho ngoana ea e-song ho tsoaloe.

Likhoeling tse 3 tse fetileng tsa moimana, li-salicylate li loantšitsoe. Ka trimester ea 3, litekanyetso tse phahameng tsa ASA li ka baka ts'ebetso ea ho pepa, tsa eketsa mali (ka ho mme le ka popelong), ho koaloa kapele hoa botallal duct ka popelong.

Tšebeliso ea ASA hang pele ho hlaha e ka baka hemorrhagic cerebrovascular kotsi (haholoholo masea a pelehi).

Li-salicylates le lihlahisoa tsa tsona tsa metabolic li fetela lebeseng la matsoele. Tsamaiso e sa lebelloang ea tekanyetso e nyane ea ASA nakong ea lebese ha e hloke ho felisoa ha letsoele mme ha e tsamaellane le nts'etsopele ea litlamorao tse sa rateheng ho ngoana. Leha ho le joalo, litekanyetso tse phahameng kapa tšebeliso e telele ea lithethefatsi tsena li hloka ho felisoa ha hepatitis B.

Tlhahlobo nakong ea kemolo e re lumella ho fihlela qeto ea hore hangata lithethefatsi li laetsoe ho thibela mathata a thrombotic lihlopheng tsa batho ba kotsing, kalafong ea ho hloka khaello ea leeme legestosishammoho le kalafo polyhydramnios.

Hoo e batlang e le bo-'mè bohle ba lebelletseng ba hlokometse hore Cardiomagnyl e mamelleha hantle, empa ntlafatso (haholoholo, pono e tlase le ho eketseha ha mali) lia bonahala kamora matsatsi a 10-14 a kalafo.

Tlhahlobo ho Cardiomagnyl

Litlhahlobo mabapi le Cardiomagnylum liforomong li fapane. Boholo ba bakuli ba noang lipilisi tsena joalo ka ha ba laetsoe ke ngaka ba khotsofatsoa ke tsona, empa ka linako tse ling litlhahlobo tse mpe li boetse li fumanoa. Mabaka a ka sehloohong a tekanyetso e tlase ea sehlahisoa ke theko ea eona e phahameng le litla-morao.

Liphetho tsa lithuto le tlhahlobo ea litsebi li bontša hore ASA ke eona lithethefatsi tse ka sehloohong kalafo ea antithrombotic ho bakuli ba kotsing lefu la pelo (ho kenyelletsa le tse etsahalang nakong ea kemaro).

Karolo ea bohlokoa ea Cardiomagnyl ke boteng ba Mg hydroxide ka sebopeho sa eona - "buffer" e thibelang ho hlaha hoa litlamorao tsa ASA mme, haholoholo, erythematic-hemorrhagic foromo ea NSAID gastropathy.

Boithuto bo bontšitse hore Cardiomagnyl e sebetsa hantle ho feta mefuta ea litekanyetso tsa ento le ho thibela bongata. palo ea liplatelete. Maemong ana, khafetsa ea lintho tse mpe tse etsahalang tsamaisong ea tšilo ea lijo e ne e le tlase haholo ha ho bapisoa le ho tloaelehileng Asipirin le Asipirine fumanehang ka tsela ea matlapa a enteric.

Kahoo, ho ba le matšoao a tšoanang le li-contraindication bakeng sa tšebeliso joalo ka ASA e tloaelehileng, Cardiomagnyl e bolokehile haholo, empa ha e sebetse hantle bakeng sa thibelo ea mathata a mafu a CCC.

Theko ea Cardiomagnyl: 75 mg / 15.2 mg le 150 mg / 30.39 mg ke bokae?

Theko e tloaelehileng ea matlapa a Cardiomagnyl 75 mg No. 100 ho li-pharmacies tsa Ukraine ke 85 UAH. O ka reka matlapa a Forte bakeng sa U 95-98 UAH (o jara No. 100). Ka nako e ts'oanang, litšenyehelo tsa lithethefatsi ho Zaporozhye, Kiev, Kharkov kapa Odessa li fapana hanyane.

Theko ea Cardiomagnyl ho la Moscow le St. Petersburg e tsoa li-ruble tse 120. bakeng sa ho paka No. 30 le ho tloha 215 li-ruble. bakeng sa ho paka No. 100. Litsenyehelo tsa matlapa a Forte li tsoa ho 125 bakeng sa sephutheloana sa li-ruble tsa No. 30 le 260. le ho tloha bakeng sa ho paka liphoso No. 100.

Cardiomagnyl Theko

Litšenyehelo tse tloaelehileng tsa matlapa a Cardiomagnyl a fumanehang ka har'a meriana ea Moscow a ipapisitse le palo ea tsona ka har'a sephutheloana, hammoho le khatello ea acetylsalicylic acid: