Acekardol: litaelo tsa tšebeliso, li-analogues le litekolo, litheko lithekising tsa meriana ea Russia

Fumana sera se hlapanyelitsoeng MUSHROOM ea lipekere! Manala a hau a tla hloekisoa ka matsatsi a 3! E nke.

U ka etsa joang hore khatello ea methapo e potlakise kapele ka mor'a lilemo tse 40? Risepe e bonolo, ngola fatše.

Na u khathetse ke li-hemorrhoids? Ho na le tsela ea ho tsoa! E ka phekoloa lapeng ka matsatsi a 'maloa, u hloka ho.

Mabapi le ho ba teng ha liboko ho TSOA molomong! Hang ka letsatsi, noa metsi ka lerotholi ..

Litlamorao

Ho latela maikutlo, Acecardol le analogue ea eona li ka baka litlamorao tse latelang.

• Hematopoietic system: phokolo ea mali, menyetla ea ho tsoa mali,
• Sistimi ea maikutlo: bronchospasm,
• Allergies: urticaria, lekhopho la letlalo, ho hlohlona, ​​edema ea Quincke, lefu la pelo le methapo ea methapo, ho ruruha ha mucosa ea nasal, ho thothomela hoa kelello,
• Tsamaiso ea methapo e bohareng: tahlehelo ea kutlo, tinnitus, ho tsekela, ho opeloa ke hlooho: Ho opeloa ke mpa, ho opeloa ke pelo, ho nyekeloa ke pelo, ho hlatsa, mala a ka mpeng le liso tsa methapo ea tsebe.

Boloetse bo bongata ha bo na monyetla, kaha ntho e sebetsang, acetylsalicylic acid, e fumaneha ka tekanyo e nyane. Litekanyetso tse ngata tsa ASA li ka baka mali ho tsoa ka mpeng.

Bokhachane le pelehi

Bokhachane le pelehi ke litlatsetso tse ka sehloohong ts'ebelisong ea lithethefatsi Acekardol. Moemeli oa antiplatelet o thibetsoe ka tieo ho trimester ea 1 le ea 3 ea bokhachane, ho trimester ea bobeli e lokelang ho nkuoa ka hloko mme feela joalokaha ho laetsoe ke ngaka. Ho amoheloa ho trimester ea bobeli ho bohlokoa feela ha feela melemo ea kalafo ho mme e ka feta ts'oaetso ho lesea.

Analogs Acekardol

Analogue ea sebopeho sa ntho e sebetsang:

• Anopyrine,
• BOTSA-Cardio,
• Aspicore
• Aspinat
• Aspirin York
• Aspirin
• Aspirin 1000
• Aspirin Cardio,
• Aspirin Express,
• Acenterin,
• Acetylsalicylic acid
• Acylpyrine,
• Atsbirin,
• Bufferin
• CardiASK,
• Cardiomagnyl
• Colpharite
• Mikristin
• Plidol 100,
• Plidol 300,
• Polokard,
• Taspir
• Thrombo ACC,
• Thrombogard 100,
• Thrombopol
• Walsh Asalgin,
• Upsarin UPSA,
• HSN Payne.

Tlhokomeliso: ts'ebeliso ea li-analogues e lokela ho lumellana le ngaka e eang.

Theko e tloaelehileng ea ATSECARDOL, matlapa a litlhare tsa meriana (Moscow) ke li-ruble tse 25.

Sokolla foromo le sebopeho

Acecardol e hlahisoa ka mokhoa oa matlapa a biconvex a pota-potileng, a koahetsoeng ka khetla e tšoeu.

Letlapa le le leng le na le:

• Ntho e sebetsang: acetylsalicylic acid (ASA) - 50, 100 kapa 300 mg,
• Likarolo tse thusang: lactose, titanium dioxide, magnesium stearate, oli ea castor, cellcrystalline cellulose, povidone, starch ea poone.

Litlamorao

Taeo e hlokomelisa ka monyetla oa ho etsa litla-morao tse latelang ha u fana ka taelo ea Acekardol:

• Karolong ea mokhoa oa ho hema: bronchospasm,
• Ho tloha lehlakoreng la tsamaiso ea methapo e bohareng: tinnitus, ho se utloe litsebeng, ho tsekela, hlooho,
• Ho tsoa ho tsamaiso ea hemopoietic: anemia, monyetla o eketsehileng oa ho tsoa mali,
• Ho tloha tšilo ea lijo: ho otla ha pelo, ho hlatsa, ho nyekeloa, seso sa duodenal, mucosa ea ka mpeng, ho tsoa mali ka mpeng, ho senyeha ha tšebetso ea sebete,
• Litla-morao: Lintho tse bohloko ka letlalo: ho hlohlona ha letlalo, lekhopho, urticaria, rhinitis, edema ea Quincke, ho thothomela ha anaphylactic.

Contraindication

Acekardol e kopantsoe le linyeoe tse latelang:

• pelo e sa foleng
• Ho hlaba haholo le ho re hlaba ka thata,
• ho mpefala ha bohloko ba ho ruruha le ho ruruha ha liso ka mpeng.
• hemorrhagic diathesis,
• lefu la ka mpeng,
• hypersensitivity ho acetylsalicylic acid,
• asthma ea lefu la bronchial,
• khaello ea lactase, malabsorption ea glucose-galactose, mamello ea lactose,
• ho nka methotrexate ka tekanyetso ea beke le beke ea 15 mg kapa ho feta, nakong ea kemaro le ho lactation, ka tlase ho lilemo tse 18.

Abela ka hloko ha:

• mosebetsi o sa sebetseng oa liphio le sebete,
• hyperuricemia, gout,
• nalane ea ulcer ea ka mpeng le seso sa duodenal,
• Mafu a sa foleng a amanang le ho phefumoloha, polyposis ea ka mpeng, hay fever, allergy.
• phekolo e kopanyang anticoagulant,
• ho nka methotrexate ka tekanyetso ea beke le beke ea ka tlase ho 15 mg, koteng ea bobeli ea bokhachane le pele ho ts'ebetso e ts'ebetsoeng ea ho buoa (ho kenyeletsoa le e nyane).

Bongata

Matšoao a sebelisang matla a ho feta a tlhaho a kenyelletsa ho tsekela, ho nyekeloa ke pelo, hlooho, pherekano, tinnitus, ho fufuleloa haholo, tachypnea le khatello ea mali.

Khothaletso e matlafalitsoeng ea tšebeliso ea mali, tšebeliso ea khabone e tsitsitseng le ho khutlisetsa tekanyo ea motlakase oa motlakase.

Ka overdose e matla, ho ka khoneha - mocheso o phahameng haholo oa 'mele, khatello ea phefumoloho, tsamaiso ea pelo, tsamaiso ea methapo, metabolism ea glucose, mali a tsoang ka mpeng le mala.

Maemong ana, ho hlokahala sepetlele ka potlako le kalafo ea tšohanyetso, ho kenyelletsa ho hlatsoa tšupa ea mpa, ho sebelisoa khafetsa ha khase e sebetsang, hemodialysis, khatello ea alkaline, ho khutlisetsa boemo ba acid-base le tekanyetso ea motlakase oa metsi, hammoho le ho beoa ha lipontšo tsa kalafo tse reretsoeng ho felisa tse ntlafalitsoeng. tlolo ea molao.

Litaelo tse khethehileng

Acekardol e ka tsosa lefu la bronchospasm le asthma. Mabaka a kotsi: nalane ea polyposis ea ka mpeng, hay fever, allergy ea lithethefatsi, le asthma ea bronchial.

Phello e fumanoeng ea ho thibela ho kopana ha liplatelete e phehella matsatsi a 'maloa, e leng ho ka bakang mali nakong ea ts'ebetso ea ts'ebetso ea ts'ohanyetso. Pele ho ts'ebetso e reriloeng, moriana o hlakotsoe bonyane matsatsi a 7 pele ho nako.

Ho bakuli ba kotsing ea ho hlaseloa, Acecardol ka tekanyetso e nyane e ka baka gout. Kotsi ke ba nang le acid e nyenyefalitsoeng ea uric acid.

Ka keketseho ea tekanyetso ea moriana, menyetla ea ho tsoa mali mokokotlong oa lijo e eketseha haholo.

Ha e ame bokhoni ba ho khanna. Molemong oa ho phekola li-glucocorticosteroids, ho lokela ho hopoloa hore ka ho hlakoloa ha bona, ho ka ba le ts'oaetso e ngata ea li-salicylates.

Tšebelisano

Ho ja acecardol ho ntlafatsa ho ba le kotsi ea methotrexate, ho fokotsa ho hlaka ha eona ea renal, valproic acid. E ntlafatsa litlamorao tsa li-NSAID tse ling, li-analcics tsa narcotic, lithethefatsi tsa hypoglycemic tsa molomo, heparin, anticoagulants e sa tobang, li-thrombolytics le antiplatelet agents, sulfonamides (ho kenyelletsa Co-trimoxazole), T3. Fokotsa phello ea lithethefatsi tsa uricosuric (benzbromarone, sulfinpyrazone), lithethefatsi tse hanyetsanang le meriana, diuretics (spironolactone, furosemide).

GCS, li-ethanol le lithethefatsi tse nang le ethanol li eketsa phello e senyang mucosa ea ka mpeng, li eketsa menyetla ea ho tsoa mali.

E eketsa khatello ea "digoxin", barbiturates le letsoai la Li + ho plasma.

Li-antacid tse nang le Mg2 + le / kapa Al3 + li fokotseha butle 'me li sitisa ho kenngoa ha ASA.

Lithethefatsi tsa Myelotoxic li eketsa ponahatso ea hematotoxicity ea lithethefatsi.

Acecardol, litaelo tsa tšebeliso (Mokhoa le litekanyetso)

Moriana ona o khothalletsoa hore o nooe pele ho lijo. Ho eletsoa hore o noe matlapa ka molumo o lekaneng oa metsi. Sethethefatsi se laetsoe nako e telele. Phapang e mengata ea ho amoheloa - nako e le 'ngoe ka letsatsi.

Haeba infraction ea myocardial e mpe e belaelloa bakeng sa thibelo khetha 100 mg letsatsi le letsatsi kapa 300 mg letsatsi le leng le le leng. Matlapa a hlafunoang a fana ka phello e potlakileng, e bohlokoa haholo lihora tsa pele tsa infarction ea myocardial. Haeba ho na le mabaka a 'maloa a kotsi ka nako e le' ngoe, 300 mg letsatsi le leng le le leng, kapa 100 mg letsatsi le leng le le leng, e laetsoe ho thibela infarction ea makhopho a hlobaetsang le a mosesane.

Thibelo ea angina pectoris e sa tsitsang, tlhaselo ea pelo e pheta-phetoang, thibelo ea mafu a nakoana a amang pelo ischemic stroke: 100-300 mg letsatsi le letsatsi.

Bakeng sa thibelo ea embolism ea pulmonary, vein thrombosis e tebileng khetha 300 mg letsatsi le leng le le leng, kapa 100 mg letsatsi le letsatsi.

Bongata

Matšoao a bonolo a kang ho tsekela, ho nyekeloa ke pelo, hlooho, pherekano, tinnitus, mofufutso o feteletseng, tachypnea le hyperventilation lia etsahala. Maemong ana, kalafo e tla kenyelletsa ho ruruha ha mpa, tšebeliso e phahameng ea khabone e tsitsitseng, le ho khutlisetsa botsitso ba motlakase oa motlakase.

Ka ho teba ha lithethefatsi tse fetang tekano, ho ka khoneha: mocheso o phahameng haholo oa 'mele, khatello ea phefumoloho, tsamaiso ea methapo ea pelo, tsamaiso ea methapo, tsoekere ea glucose, mali a ka mpeng le mala. 'Me ntlheng ena ho hlokahala sepetlele se potlakileng.

Mofumahali

Kamora ho tsamaisoa ka molomo, ASA e kenella ka potlako le ka botlalo ho tsoa mpeng ea mpa, nakong eo e tšeloang karolo e itseng. Nakong ea ho monya le ka mor'a ho kenngoa, ASA e fetoha metabolite ea mantlha - acid e nang le letsoai le e tšeloang hantle ka har'a sebete (tlasa tšusumetso ea li-enzymes) ho theha metabolites joalo ka salicylic acid, salicylic acid glucuronide le phenyl salicylate. Li fumanoa liseleng tse ngata le moriring. Ho basali, ts'ebetso ea metabolic e lieha ho feta ho banna.

Kamora ho nka Acecardol kahare, phello e phahameng ea ASA ka plasma ea mali e bonoa kamora metsotso e 10-20, salicylic acid - kamora lihora tse 0,3-2.

Matlapa a Acecardol a kopantsoe le koae e thibelang acid, e thibelang sethethefatsi hore se se ke sa qhalana ka mpeng, ka hona ntho e sebetsang e lokolloa tikolohong ea alkaline ea duodenum. Mabapi le sena, ho amoheloa ha ASA ke lihora tse 3-6 butle butle ho feta ha o nka matlapa a tloaelehileng (a sa koahetsoeng ka khetla e joalo).

Li-acetylsalicylic le salicelic acid li tlama liprotheine tsa plasma (ho latela tekanyetso, letšoao lena ke 66-98%) 'me li tsamaisoa ka potlako' meleng. Asiti ea salicylic e feta ka har'a placenta ebe e kena ka lebese la matsoele.

Metabolism ea salicylic acid e lekanyelitsoe ke bokhoni ba enzymatic system, ka hona, tlhahiso ea eona e itšetlehile ka tekanyetso.Bophelo ba halofo bo nka ho tloha lihora tse 2-3 (maemong a litekanyetso tse tlase) ho isa lihora tse 15 (ha u sebelisa tekanyetso e phahameng e le antipyretic le analgesic).

Ka tšebeliso ea nako e telele, ASA e se nang hydrolyzed ha e bokellane ka har'a serum ea mali, ho fapana le li-salicylate tse ling.

Salicylic acid le metabolites ea eona li hlahisoa ke liphio. Ka ts'ebetso e tloaelehileng ea liphio, ho tloha ho 80 ho isa ho 100% ea tekanyetso e le 'ngoe ea ASA e hloekisoa nakong ea lihora tse 24-72.

Tekanyetso le tsamaiso

Matlapa a acecardol a nooa ka molomo pele ho lijo, a hlatsuoa ka metsi. Moriana ona o reretsoe hore o sebelisoe nako e telele.

Haeba infraction ea myocardial e belaelloa, Acecardol e nkuoa 100 mg hang ka letsatsi kapa 300 mg letsatsi le leng le le leng. Bakeng sa litlamorao tse matla tsa kalafo, ho ka 'na ha sebelisoa letlapa la pele.

Ho thibela infarction ea myocardial e sa khaotseng, ho koaloa ha methapo ea pelo le makala a eona ka maro a mali, methapo e tebileng ea methapo le e nang le angina e sa tsitsang, Acecardol e nkuoa ka 100-300 mg ka letsatsi.

Ho thibela thromboembolism kamora ts'ebetso e hlaselang le ea ho buoa, litekanyetso tsa Acecardol ke 100-300 mg letsatsi le letsatsi.

Bokhachane le pelehi

Ka trimester ea pele ea boimana, li-salicylate tse tekanyetso e kholo li eketsa kotsi ea ho hlaha ha lesea ka popelong (lehlaba le arohaneng, sekoli sa pelo), ka hona Acecardol e hatelletsoe ka thata bakeng sa tšebeliso.

Ka trimester ea bobeli ea boimana, moriana o ka khethoa feela haeba molemo o lebelletsoeng o hlile o phahame ho feta likotsi tse ka bang teng. Ka nako e ts'oanang, ho khothalletsoa ho sebelisa Acecardol ho litekanyetso tsa eseng fetang 150 mg bakeng sa lithuto tse khutšoane haholo tse ka bang teng.

Karolong ea boraro ea bokhachane, li-salicylates ka tekanyetso e kholo (tse fetang 300 mg / ka letsatsi) li fokolisa ho sebetsa, li baka ho tsoa madi ho mme le ka popelong, le ho koaloa kapele hoa ductus arteriosus ka popelong. Ho nka ASA hang feela pele ho tswalo ho ka lebisa ho kenngweng ha madi kahare, haholoholo maseeng a pelehi. Ntlheng ena, ho trimester ea ho qetela ea bokhachane, Acecardol e tiisitsoe ka thata bakeng sa tšebeliso.

Li-salicylates le li-metabolites tsa tsona li fetela lebeseng, ke ka lebaka leo Acecardol e kopantsoeng le basali ba anyang matsoele. Haeba ho sebelisa moriana ho na le mabaka a bohlokoa a bongaka, o lokela ho emisa ho anyesa.

Ho sebelisana le lithethefatsi

Ha ho sebelisoa ka nako e le 'ngoe, acetylsalicylic acid e nyenyefatsa phello ea lithethefatsi tse latelang: diuretics, angiotensin-converting enzyme inhibitors (ACE), lithethefatsi tsa uricosuric (benzbromarone).

Tabeng ea ts'ebeliso e le 'ngoe, acetylsalicylic acid e ntlafatsa ketso ea lithethefatsi tse latelang: li-antiplatelet agents le lithethefatsi tsa thrombolytic, digoxin, heparin le anticoagulants e sa tobang, methotrexate, valproic acid, lithethefatsi tsa hypoglycemic (insulin le sulfonylurea derivatives).

Hape, motsoako oa ASA o nang le methotrexate o amahanngoa le kotsi e eketsehang ea karabelo e mpe ho tsoa lithong tsa hemopoietic, ka li-thrombolytics, li-antiplatelet agents le anticoagulants - kotsi e eketsehileng ea ho tsoa mali.

ASA e ntlafatsa litlamorao tsa chefo ea ethanol tsamaisong ea methapo ea kutlo. Sena se eketsa menyetla ea ho senya mucous ea mucous ea liprotheine tsa ka mpeng le nako e telele ea ho tsoa mali.

Li-glucocorticosteroids tsa systemic li ntlafatsa ho felisoa ha moriana, ho feta ho fokolisa matla a lona.

Li-analogues tsa moralo oa Acecardol ke litokisetso tsa Thrombo ACC, Aspirin, Cardiopyrine, Aspinate, Aspicor, Taspir, Thrombopol, Acetylsalicylic acid.

Tlhahlobo mabapi le Acecardol

Ho latela litlhahlobo, Acekardol ke moemeli ea sebetsang oa antiplatelet o hlapollang mali mme o thibela thrombosis. Melemo ea eona e eketsehileng e kenyelletsa theko e tlase (ha ho bapisoa le li-analogues tse ngata), boiketlo ba tsamaiso (nako e le 'ngoe ka letsatsi), foromo ea tekanyetso (koae ea enteric e sireletsa mpa ho litlamorao tse mpe tsa acetylsalicylic acid), hammoho le boteng ba litekanyetso tse fapaneng tsa matlapa (50, 100 le 300 mg), e u lumellang hore u khethe tse nepahetseng haholo.

Likotsi tsa Acecardol li kenyelletsa ho ba teng ha litlolo tsa molao. Leha ho le joalo, li fumaneha bakeng sa salicylates tsohle, ka hona ngaka e lokela ho fana ka kalafo.