Diabetes analogue
Diabeteson MV (matlapa) Tekanyetso: 47
Litokisetso tsa letlapa la Russia bakeng sa kalafo ea lefu la tsoekere. Lintho tse sebetsang: gliclazide e le tekanyetso ea 60 mg ka ho pilisi. E bontšoa kalafo ea lefu la tsoekere la mofuta oa 2 le sepheo sa prophylactic.
Analogs of the drug Diabeteson MV
Analogue e theko e tlase ho tloha li-ruble tse 160.
Gliclazide MV ke litokisetso tsa letlapa bakeng sa kalafo ea mofuta oa tsoekere ea lefu la tsoekere le ipapisitse le karolo e le ngoe e sebetsang litekanyetsong tsa 30 mg. E fuoa mokhoa oa ho ja hantle le ho ikoetlisa. Gliclazide MV e hanyetsanoa ho bakuli ba nang le lefu la tsoekere la mofuta oa 1 (ba itšetlehileng ka insulin).
Analogue e theko e tlaase ho tloha li-ruble tse 168.
Glidiab ke e 'ngoe ea li-substitute tse molemo ka ho fetisisa bakeng sa gliclazide. E fumaneha hape ka sebopeho sa letlapa, empa litekanyetso tsa DV li phahame mona, tse lokelang ho tsotelloa pele ho qala kalafo. Ho bontšoa mofuta oa lefu la tsoekere la mofuta oa 2 o nang le lijo tse sa sebetseng le ho ikoetlisa.
Analogue e theko e tlaase ho tloha li-ruble tse 158.
Akrikhin (Russia) Glidiab ke e 'ngoe ea tse molemo ka ho fetisisa tse nkang sebaka sa gliclazide. E fumaneha hape ka sebopeho sa letlapa, empa litekanyetso tsa DV li phahame mona, tse lokelang ho tsotelloa pele ho qala kalafo. Ho bontšoa mofuta oa lefu la tsoekere la mofuta oa 2 o nang le lijo tse sa sebetseng le ho ikoetlisa.
Tlhaloso ea lithethefatsi
Lefu la tsoekere - Glyclazide ke sulfonylurea e tsoang ho eona, setlhare sa molomo sa hypoglycemic se fapaneng le lithethefatsi tse tšoanang ka ho ba teng ha reng e nang le heterocyclic ea N e nang le tlamo ea endocyclic.
Gliclazide e fokotsa khatello ea "glucose" e ngata maling, 'me e ntlafatsa secretion ea "insulin" ke li-islets tsa Langerhans. Keketseho ea boemo ba insulin ea postprandial le C-peptide e phehella kamora lilemo tse peli tsa kalafo. Ntle le phello ea metabolism ea carbohydrate, gliclazide e na le litlamorao tsa hemovascular.
Kameho ho secretion ea insulin
Ho mofuta oa 2 lefu la tsoekere, lithethefatsi li khutlisa tlhoko ea pele ea "insulin secretion" ho arabela tšebeliso ea tsoekere le ho matlafatsa karolo ea bobeli ea seculin ea insulin. Keketseho e kholo ea secretion ea insulin e bonoa ho arabela ts'usumetso ka lebaka la ho ja lijo le tsamaiso ea tsoekere.
Glyclazide e fokotsa kotsi ea methapo e nyane ea methapo ea mali, e amang methapo e ka lebisang ho ntlafatseng ha mathata a lefu la tsoekere: ho thibela likarolo tsa methapo le ho khomarela le ho fokotseha ha lintho tse ngata tse amanang le mokokotlo (beta-thromboglobulin, thromboxane B2), hammoho le ho khutlisetsoa ha methapo ea methapo ea methapo ea mali. le ts'ebetso e eketsehileng ea activator ea tisy ea plasminogen.
Taolo e matla ea glycemic e thehiloeng ts'ebelisong ea moriana Diabeteson ® MB (glycosylated hemoglobin (HbA1c ® MB) le ho eketsa tekanyetso ea eona khahlanong le semelo (kapa ho e-na le hoo) kalafo e tloaelehileng pele o eketsa lithethefatsi tse ling tsa hypoglycemic (mohlala, metformin, alpha-glucosidase inhibitor kapa insulin. Karolelano ea letsatsi le letsatsi ea lithethefatsi Diabeteson ® MB ho bakuli ba sehlopha sa taolo e matla e ne e le 103 mg, palo e phahameng ea letsatsi le letsatsi e ne e le 120 mg.
Khahlano le semelo sa ts'ebeliso ea lithethefatsi Diabeteson ® MB sehlopheng se matla sa taolo ea glycemic (ho latela lilemo tse 4,8, ka kakaretso HbA1c 6.5%) ha se bapisoa le sehlopha se tloaelehileng sa taolo (HbA1c 7.3%), phokotseho e kholo ea 10% kotsing e atamelaneng ea maqhubu a kopaneng a macro- le mathata a microvascular.
Monyetla ona o fumanoe ka ho fokotsa kotsi e kaalo: mathata a maholo a microvascular ka 14%, ho qala le ho tsoelapele ha nephropathy ka 21%, ho hlaha ha microalbuminuria ka 9%, macroalbuminuria ka 30% le nts'etsopele ea mathata a renal ka 11%.
Melemo ea taolo ea glycemic e matla ha u ntse u nka Diabeteson ® MB ha ea ka ea itšetleha ka melemo e fumanoeng ka kalafo ea antihypertensive.
Tlhaloso ea Sehlahisoa
Diabeteson ke moemeli oa hypoglycemic le litlamorao tse fanoang ka molomo. Phapang ea eona ho li-synonyms ke ho ba teng ha reng e nang le heterocyclic ea N e nang le tlamo ea endocyclic. Moriana ona o khothaletsa tlhahiso ea "insulin" ke li-cells-cell tsa lihlekehleke tsa Langerhans le ho fokotsa sekhahla sa tsoekere e maling.
Kamora kalafo ea lilemo tse peli, keketseho ea bongata ba C-peptide le postprandial insulin. Karolo e sebetsang e bonts'a litla-morao tsa hemovascular mme e ama metabolism ea carbohydrate. Mofuteng oa 2 oa lefu la tsoekere, e eketsa mohato oa bobeli oa ho ipatela ka insulin hape e khutlisa tlhoro ea secretion ea tsoekere ea glucose. Ts'ebetso tsena li shebiloe haholo-holo ka kenyelletso ea eona le karabelo ea phello, e bakoang ke takatso ea lijo.
Moriana o fokotsa kotsi ea "thrombosis" e nyane ea mali le nts'etsopele ea mathata a hlahisoang ke lefu la tsoekere. Kamora letsatsi la tšebeliso e le 'ngoe ea lithethefatsi, phello ea metabolites e sebetsang le pioglitazone e serum ea mali e lula e le boemong bo phahameng haholo.
Litaelo tsa ho sebelisoa
Sengoloa se bontša meeli ea ho nka meriana. Li-contraindication tsa tsona tse ka sehloohong ke maemo a latelang:
lefu la tsoekere le letšollo,- Nako ea ho beleha le ho ba le ngoana,
- ho hloleha ho matla ha hepatic le renal,
- litaba tse phahameng tsa 'mele oa ketone le glucose ea mali,
- mamello ho lactose, sulfanilamide, gliclazide.
lefu la tsoekere le letšollo,Setlhare sena se fuoa feela bakuli ba baholo. Letlapa le lokela ho nooa hang ka letsatsi nakong ea lijo. Tekanyetso e kholo ea letsatsi le letsatsi ke 120 mg. Setlhare se ke ke sa qhekelloa le ho hlafuna, se tlameha ho hlatsuoa ka metsi a hlakileng. Haeba u tlil'o nooa moriana, ho nooa meriana e 'meli.
Boemong ba pele ba kalafo, lethal dose ke 30 mg. Haeba ho hlokahala, e eketsoa ke setsebi pele ho matsatsi a 40 kamora ho khethoa ha e fetileng. Bakuli ba kaholimo ho lilemo tse 65 ha ba hloke phetoho ea litekanyetso. Nakong ea kalafo, nako ea ho tlosoa ha meriana e fetileng e lokela ho nahaneloa. Ha u sebelisa lithethefatsi, ho ka hlaha maemo a mabe. Tsena li kenyeletsa:
ho lahleheloa ke kelello- ho otsela ho eketsehileng kapa ho hloka boroko,
- nyakallo ea letsoalo
- haelellang
- cramps le bofokoli bo akaretsang,
- Pherekano e sa bonahaleng, ho tsekela.
ho lahleheloa ke kelelloLi-analog le litlatsetso tsa lithethefatsi
Lithethefatsi li na le litšenyehelo tse phahameng haholo. Li-analog le tsa lefu la tsoekere li emeloa ke litlhare tse latelang:
- Diabetesalong
- Glyclazide
- Glidiab
- Diabefarm MV,
- Predian
- Glucostabil,
- Piroglar.
Diabetesalong - Analogue e theko e tlase ea lefu la tsoekere, e kopanyang tlhahiso ea insulin, kutloisiso ea lisele tsa thipa le ho fokotsa bongata ba tsoekere maling. Ha e lemalle esita le ka mor'a lilemo tse 3 tsa ts'ebeliso. Setlhare se fokotsa khatello ea kelello ea "postprandial hyperglycemia", e khutlisetsa tlhoro ea pele ea tlhahiso ea insulin, e fokotsa nako ea nako pakeng tsa ho ja le ho boloka insulin. Sebeteng, sethethefatsi se fokotsa sebopeho sa tsoekere 'me se etsa hore se sebetse hantle.
Ntho e sebetsang e ntlafatsa metabolism ea mmele le carbohydrate, e fokotsa kotsi ea thrombosis mme e khutlisetse ts'ebetso ea activator ea tisy plasminogen.
Gliclazide - Ona ke mofuta oa lithethefatsi tse fanoang kahare. E kenyelletsa selikalikoe sa heterocyclic ka tlamo ea endocyclic. Setlhare se khothalletsa tlhahiso ea insulin hape se fokotsa bongata ba tsoekere. Kamora kalafo ea lilemo tse tharo, keketseho ea khatello ea C-peptide le postprandial insulin e ntse e le teng. Karolo e sebetsang e bonts'a tšebetso ea methapo ea methapo 'me e ama metabolism ea carbohydrate. Ho sebelisa moriana ho fokotsa kotsi ea mathata a lefu la tsoekere.
Glidiab ke lithethefatsi tsa tsoekere tsa moloko oa 2-sulfonylurea le hypoglycemic. E ntlafatsa ts'ebetso ea sephiri ea insulin ea tsoekere, kutloisiso ea mesifa ea pherekano mme e na le phello e ntle ho secretion ea insulin, e tsosa ketso ea methapo ea methapo ea methapo ea methapo le ho fokotsa tlhoro ea hyperglycemia kamora ho ja. Tšebeliso ea meriana e lokela ho qala khahlanong le lijo tse nang le khalori e tlase.
Ho khothalletsoa ho lula u lekola boemo ba tsoekere maling maling ka mor'a ho ja le ka mpeng e se nang letho. Tekanyetso e lokisoa bakeng sa khatello ea maikutlo kapa ea 'mele.
Diabefarm MV - Ena ke analogue ea lefu la tsoekere la 60, e leng lithethefatsi tse amanang le hypoglycemic ebile li amana le moloko oa bobeli oa litlamorao tsa sulfonylurea. E kenya letsoho tlhahiso ea insulin ke lisele tsa manyeme le ketso ea li-enzyme tse ka hare. Moriana o sebetsa hantle haholo mofuteng oa 2 oa "mellitus" o amanang le lefu la tsoekere ka lipontšo tsa lefu la tsoekere le lefu la tsoekere le prophylactic ea mathata a microcirculatory.
Predian - meriana ea tlhaho e entsoeng ka maiketsetso. E ka rekoa ka mokhoa oa matlapa a nang le litekanyetso tsa 0,08 g, e pakiloeng ka lebokoseng la karete. Motsoako o sebetsang o theola mali le ho fokotsa tsoekere. Moriana o tlameha ho qala ka halofo ea pilisi. Moriana o ke ke oa kopantsoe le acetylsalicylic acid, butadione, amidopyrine ka lebaka la ts'okelo ea hypoglycemia.
Glucostabil e ntlafatsa ts'ebetso ea methapo ea methapo ea methapo, e fokotsa nts'etsopele ea "parietal thrombus" e kopantsoeng le liplatelete. Lithethefatsi li eketsa microcirculation, palo ea HDL-C, e fokotsa cholesterol e felletseng, kutloisiso ea methapo ea mali ho adrenaline mme e thibela nts'etsopele ea atherosclerosis le microthrombosis. Ho fokotseha ha nako e telele ha proteinuria ho hlokomeloa ho latela tšebeliso ea nako e telele ea gliclazide ho lefu la tsoekere.
Peoglar - moriana oa molomo oa hypoglycemic le agonist e matla ea khetho ea "ma " Karolo e sebetsang e bonts'a phetoho liphatseng tsa lefutso tse amehang ho phatloheng ha lipid le taolo ea tsoekere. Sebeteng le linthong tse poteletseng, e fokotsa khatello ea insulin. Le mofuta oa lefu la tsoekere la mofuta oa 2 mellitus lowers glycated hemoglobin le insulin ho plasma.
O ka tseba hore na lefu la tsoekere le ka nkela ngaka ea hau sebaka joang. Ha ho kgothaletswe ho sebelisa moriana u le mong, kaha sena se ka lebisa litlamorao tse kotsi.
Li-analog mabapi le sebopeho le pontšo ea ts'ebeliso
| Sehlooho | Theko ho la Russia | Theko Ukraine |
|---|---|---|
| Bisogamma Glyclazide | 91 rub | 182 UAH |
| Glidiab Glyclazide | 100 rub | 170 UAH |
| Diagnizide mr Gliclazide | -- | 15 UAH |
| Glidia MV Gliclazide | -- | -- |
| Glykinorm Gliclazide | -- | -- |
| Gliclazide Gliclazide | 211 rub | 44 UAH |
| Glyclazide 30 MV-Indar Glyclazide | -- | -- |
| Glyclazide-Health Gliclazide | -- | 36 UAH |
| Glioral Glyclazide | -- | -- |
| Lekola Gliclazide | -- | 14 UAH |
| Diazide MV Gliclazide | -- | 46 UAH |
| Osliklid Gliclazide | -- | 68 UAH |
| Diadeon gliclazide | -- | -- |
| Glyclazide MV Gliclazide | 4 rub | -- |
Lethathamo le ka holimo la li-analogues tsa lithethefatsi, tse bontshang Diabeteson MF, e loketse haholo hobane e na le sebopeho se tšoanang sa lintho tse sebetsang ebile e lumellana ho latela sesupo sa tšebeliso
Li-analoggs ka pontšo le mokhoa oa ts'ebeliso
| Sehlooho | Theko ho la Russia | Theko Ukraine |
|---|---|---|
| Glibenclamide Glibenclamide | 30 rub | 7 UAH |
| Maninyl Glibenclamide | 54 rub | 37 UAH |
| Glibenclamide-Health Glibenclamide | -- | 12 UAH |
| Glyurenorm glycidone | 94 rub | 43 UAH |
| Amaril | 27 rub | 4 UAH |
| Glemaz glimepiride | -- | -- |
| Glian glimepiride | -- | 77 UAH |
| Glimepiride Glyride | -- | 149 UAH |
| Glimepiride diapiride | -- | 23 UAH |
| Aletare | -- | 12 UAH |
| Glimax glimepiride | -- | 35 UAH |
| Glimepiride-Lugal glimepiride | -- | 69 UAH |
| Clay Glimepiride | -- | 66 UAH |
| Diabrex glimepiride | -- | 142 UAH |
| Meglimide glimepiride | -- | -- |
| Melpamide Glimepiride | -- | 84 UAH |
| Perinel glimepiride | -- | -- |
| Glempid | -- | -- |
| Ke thabo | -- | -- |
| Glimepiride glimepiride | 27 rub | 42 UAH |
| Glimepiride-teva glimepiride | -- | 57 UAH |
| Glimepiride Canon glimepiride | 50 rub | -- |
| Glimepiride Pharmacyard glimepiride | -- | -- |
| Dimaril glimepiride | -- | 21 UAH |
| Glamepiride diamerid | 2 rub | -- |
Moetso o fapaneng o kanna oa lumellana ho bonts'a mokhoa le mokhoa oa ts'ebeliso
| Sehlooho | Theko ho la Russia | Theko Ukraine |
|---|---|---|
| Rosiglitazone e sebetsang, metformin hydrochloride | -- | -- |
| Bagomet Metformin | -- | 30 UAH |
| Glucofage metformin | 12 rub | 15 UAH |
| Glucophage xr metformin | -- | 50 UAH |
| Reduxin Met Metformin, Sibutramine | 20 rub | -- |
| Dianormet | -- | 19 UAH |
| Diaformin metformin | -- | 5 UAH |
| Metformin metformin | 13 rub | 12 UAH |
| Metformin sandoz metformin | -- | 13 UAH |
| Siofor | 208 rub | 27 UAH |
| Foromo Metformin Hydrochloride | -- | -- |
| Emnorm EP Metformin | -- | -- |
| Megifort Metformin | -- | 15 UAH |
| Metamine Metformin | -- | 20 UAH |
| Metamine SR Metformin | -- | 20 UAH |
| Metfogamma metformin | 256 rub | 17 UAH |
| Tefor metformin | -- | -- |
| Glycometer | -- | -- |
| Glycomet SR | -- | -- |
| Forthine | 37 rub | -- |
| Metformin Canon metformin, ovidone K 90, starch ea poone, crospovidone, magnesium stearate, talc | 26 rub | -- |
| Insuffor metformin hydrochloride | -- | 25 UAH |
| Metformin-teva metformin | 43 rub | 22 UAH |
| Diaformin SR metformin | -- | 18 UAH |
| Mepharmil Metformin | -- | 13 UAH |
| Metformin Farmland Metformin | -- | -- |
| Amaryl M Limepiride Micronized, Metformin Hydrochloride | 856 rub | 40 UAH |
| Glibomet glibenclamide, metformin | 257 rub | 101 UAH |
| Glucovans glibenclamide, metformin | 34 rub | 8 UAH |
| Dianorm-m Glyclazide, Metformin | -- | 115 UAH |
| Dibizid-m glipizide, metformin | -- | 30 UAH |
| Douglimax glimepiride, metformin | -- | 44 UAH |
| Duotrol glibenclamide, metformin | -- | -- |
| Gluconorm | 45 rub | -- |
| Glibofor metformin hydrochloride, glibenclamide | -- | 16 UAH |
| Avandamet | -- | -- |
| Avandaglim | -- | -- |
| Janumet metformin, sitagliptin | 9 rub | 1 UAH |
| Velmetia metformin, sitagliptin | 6026 rub | -- |
| Galvus Met vildagliptin, metformin | 259 rub | 1195 UAH |
| Tripride glimepiride, metformin, pioglitazone | -- | 83 UAH |
| Comboglize XR metformin, saxagliptin | -- | 424 UAH |
| Comboglyz Prolong metformin, saxagliptin | 130 rub | -- |
| Gentadueto linagliptin, metformin | -- | -- |
| Vipdomet metformin, alogliptin | 55 rub | 1750 UAH |
| Sinjardi empagliflozin, metformin hydrochloride | 240 rub | -- |
| Voglibose Oxide | -- | 21 UAH |
| Glutazone pioglitazone | -- | 66 UAH |
| Dropia Sanovel pioglitazone | -- | -- |
| Januvia sitagliptin | 1369 rub | 277 UAH |
| Galvus vildagliptin | 245 rub | 895 UAH |
| Onglisa saxagliptin | 1472 rub | 48 UAH |
| Nesina alogliptin | -- | -- |
| Vipidia alogliptin | 350 rub | 1250 UAH |
| Trazhenta linagliptin | 89 rub | 1434 UAH |
| Lixumia lixisenatide | -- | 2498 UAH |
| Sebaka sa Guarem Guar | 9950 rub | 24 UAH |
| Insvada repaglinide | -- | -- |
| Novonorm Repaglinide | 100 rub | 90 UAH |
| Repodiab Repaglinide | -- | -- |
| Baeta Exenatide | 150 rub | 4600 UAH |
| Baeta Long Exenatide | 10248 rub | -- |
| Viktoza liraglutide | 8823 rub | 2900 UAH |
| Saxenda liraglutide | 1374 rub | 13773 UAH |
| Forksiga Dapagliflozin | -- | 18 UAH |
| Forsiga Dapagliflozin | 12 rub | 3200 UAH |
| Invocana canagliflozin | 13 rub | 3200 UAH |
| Jardins Empagliflozin | 222 rub | 561 UAH |
| Trulicity Dulaglutide | 115 rub | -- |
U ka fumana analogue e theko e tlaase ea moriana o theko e phahameng?
Ho fumana analogue e theko e phahameng ea moriana, mofuta o tšoanang kapa oa mantsoe, pele ho tsohle re khothaletsa ho ela hloko sebopeho, e leng lintho le lipontšo tse tšoanang tse sebetsang. Metsoako e tšoanang ea lithethefatsi e tla bonts'a hore lithethefatsi li tsamaisana le lithethefatsi, li ka lekana meriana kapa li ka etsa meriana. Leha ho le joalo, u se ke oa lebala ka likarolo tse sa sebetseng tsa lithethefatsi tse tšoanang, tse ka amang polokeho le ts'ebetso. Se ke la lebala ka litaelo tsa lingaka, ho itlama ho ka lematsa bophelo ba hau, ka hona, etela ngaka ea hau kamehla pele u sebelisa meriana leha e le efe.
Diabeteson MR Theko
Litsing tse ka tlase u ka fumana litheko tsa MR Diabeteson mme o fumane ka ho fumaneha ha khoebo ea meriana e haufinyane
- Theko ea Diabeteson MR Russia
- Theko ea Diabeteson MR Ukraine
- Theko ea Diabeteson MR e Kazakhstan
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Libaktheria tsa kahare ke sebetsa se secha khahlanong le lefu la tsoekere la mofuta oa 2
Bo-ramahlale: Libaktheria tsa kahare tsa tlhaho li sireletsa khahlanong le lefu la tsoekere la mofuta oa 2 le ka u sirelletsang khahlanong le lefu la tsoekere la mofuta oa 2. Sena se bontšoa ke litholoana tsa boithuto bo bocha bo entsoeng Univesithing ea Eastern Finland. ... -
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