Thioctic Acid > Lijo tsa lefu la tsoekere

Ke eng alpha lipoic acid? Thioctic acid le eona e na le mabitso thioctacid, lipoic acid. Ke ntho e kang vithamine, cofactor ea pyruvate dehydrogenase le alpha-ketoglutarate dehydrogenase complexes, antioxidant.

Ntho ena e entsoe ka mokhoa oa phofo e bobebe ea kristale e bobebe, e sa qhibilihang ka metsing empa e qhibiliha habonolo ka har'a ethanol. Litlhare sebelisa mofuta o qhibilihang oa motsoako oa lik'hemik'hale - letsoai la sodium. Ntho e fumanoa ka bongata ka har'a sebete, spinach, liphio le pelo, raese. Ka tloaelo 'mele o khona ho kopanya ka ho lekaneng alpha lipoic acid. Moriana o ntšoa ka mokhoa oa ho tsepamisa mohopolo bakeng sa tharollo ea infusion le ente ea methapo, ka mokhoa oa matlapa a koahetsoeng.

Ho aha Alpha Lipoic Acid

Ntho e sebelisoa ke baatlelete ho e tlosa li-radicals tsa mahala le ho fokotsa oxidation kamora boikoetliso. Sesebelisoa se fokotsa ho timetsoa ha liprotheine le lisele, ho potlakisa ho hlaphoheloa kamora ho ikoetlisa. Ntho ena e boetse e potlakisa le ho ntlafatsa monko oa tsoekere ka mesifa, e matlafatsa lits'ebetso tsa ho boloka. glycogen. Ho boetse ho lumeloa hore asiti e ka sebelisoa e le setlamorao se sebetsang sa mafura.

Pharmacodynamics le pharmacokinetics

Thioctic Acid - coenzyme ea oxarative decarboxylation pyruvic asiti le tse fapaneng alpha keto acids. Ntho ena e nka karolo ho matla, lipid le carbohydrate metabolism. k'holeseterolee tlama li-radicals tsa mahala. Tlas'a ketso ea moriana, ts'ebetso ea sebete e ntlafala, e hlahisoa ka mafolofolo glycogen. Litlamorao tsa exo native le endo native ha li nke lehlakore chefojoala. Ka ts'ebetso ea eona ea biochemical, sethethefatsi se haufi Li-vithamine tsa B.

Ha o eketsa alpha lipoic acid ka litharollo tsa tsamaiso e kenelletseng (hammoho le tharollo ea tharollo), botebo ba karabelo e mpe ea lithethefatsi bo fokotseha.

Kamora ho tsamaisoa ka molomo, haholo-holo ntle le lijo, ntho ena e kenella ka botlalo 'me e kenella ka potlako pampiring ea tšilo ea lijo. Bioavailability e fihla ho 30-60%, hobane sehlahisoa se kenella ka har'a biyopransformation. Ka liseleng tsa sebete, moriana o lokisoa. E hloekisoa ke liphio. Ho felisoa ha halofo ea bophelo ho etsahala ho tloha metsotso e 20 ho fihlela hora.

Matšoao a ho sebelisoa

ho lefu la tsoekere la polyneuropathy,
bakuli ba nang lekhoba la joala la joala,
e le karolo ea kalafo e rarahaneng mafura a sebete, cirrhosissa foleng hepatitislino tse fapaneng le lino tse chefo,
ka kalafo le thibelo Hyperlipidemia.

Contraindication

Sesebelisoa ha se sebelise:

ho allergy,
ho bana ba ka tlase ho lilemo tse 6,
ka tlase ho lilemo tse 18 ka kalafo polyneuropathy,
nakong ea ea boimana,
basali nakong ea kemaro.

Alpha Lipoic Acid ente

E matla polyneuropathy 600 mg ea lithethefatsi e fanoa ka methapo, butle, 50 mg ka motsotso. Ho tsepamisa mohopolo hoa holisoa sodium chloride. Khafetsa ea tsamaiso ke hang ka letsatsi. Haeba ho hlokahala, tekanyetso e ka eketsoa ho 1,2 g ka letsatsi. Nako ea kalafo e fihlile ho libeke tse 4.

Intramuscularly, ha e khothaletsoe ho tsamaisa tse fetang 50 mg ka nako. Hoa hlokahala hore nako le nako u fetole sebaka sa ente.

Alpha-lipoic Evalar e nkuoa ho latela litaelo tsa moetsi.

Tšebelisano

Moriana o fokotsa tšebetso cisplatine ntlafatsa phello ea lithethefatsi tsa hypoglycemic ea molomo mme insulin.

Ntho ha ea lokela ho tsoakoa ka sejaneng se tšoanang dextrose, Tharollo ea ringer, ethanol, le tharollo e arabelang ho Lihlopheng tsa SH le ho senya marokho.

Ethanol le lithethefatsi tse nang le joala ba ethyl li nyenyefatsa phello ea ho ja acid e ngata.

Litaelo tse khethehileng

Pele o qala kalafo ea bakuli ba nang le lefu la tsoekere Ho khothalletsoa hore o buisane le ngaka le ho hlahloba tsoekere ea hau ea mali.

Ampoules ka tharollo alpha lipoic acid e ke ke ea bolokoa leseling ka nako e telele. Tlosa ka lebokoseng hang-hang pele u sebelisa.

Litokisetso tse nang le (Analogs of Thioctic Acid)

Ho na le lithethefatsi tse ngata tsa molomo le ente e thehiloeng ho Thioctic Acid.

Litokisetso tse ngata: Turboslim, Bio e kholo, Selmevit E matla, Complivite Trimesterum (1 trimester, 2 trimester le 3 trimester).

Litlhaloso tsa lingaka mabapi le alpha lipoic acid li ntle haholo. Mori o bolokehile haholo hore o ka sebelisoa, ka seoelo o baka karabelo e mpe (ka tsamaiso ea methapo e meholo), bakuli ba e mamella hantle, hangata litlhare li fanoa e le karolo ea kalafo e phethahetseng hammoho le livithamini le lithethefatsi tse ling.

Ho na le litlhahlobo tse ngata mabapi le Thioctic Acid bakeng sa ho theola boima ba 'mele:

“... Ke ile ka qeta ho sebelisa moriana haufinyane. Ke ile ka latela ho ja, ka ikoetlisa. Ke fokotse mmele, ke thabile haholo ka tsohle”,
“... Ha ke sa le ngoana, ke ile ka fuoa acid ena ke ngaka kalafong ea dyskinesia, ho tloha ka nako eo ho bile le mathata a kang bile. Empa ka linako tse ling ke nka ntho ena bakeng sa thibelo. Ke ikutloa ke thabile”,
“... Kamora thupelo, ke lula ke lahleheloa ke li-kilos tse 'maloa, ke ikutloa ke le bobebe' meleng, ha ke sa batla ho ja mafura le monate”,
“... Ke noele thupelo e felletseng, ke sebelisitse chelete le nako, ke ea ho sebopeho joalo ka mehleng, empa ha ke a bona sephetho. Ke tšenyo ea chelete feela”,
“... Ho lokile, kannete, hore mori o theko e tlase ebile ha ke na karabelo e mpe, ka mor'a moo, ke livithamine. Empa ha ho khonehe ho re ke ne nke ke ka theola 'mele ka kotloloho ho tsoa ho eena. Boima bo lula bo tšoana”.

Theko ea Thioctic Acid, moo u ka rekang

Theko ea 600 mg Thioctic Acid matlapeng Berlition 300 (300 mg ka ho pepa, 2 ka letsatsi) ke li-ruble tse 750 bakeng sa likotoana tse 30, e leng matsatsi a 15. Reka alpha-lipoic acid ho Russia Federation ka mokhoa oa matlapa a ho koahelang filimi, 12 mg e ngoe le e ngoe e ka ba li-ruble tse 40, likotoana tse 50. Theko ea alpha lipoic acid (Lipoic acid forte DD) ho Ukraine ke hoo e ka bang 70 hryvnia bakeng sa matlapa a 50.

Thuto: O qetile Kolecheng ea Rivne State Basic Medical College ka lengolo la degree. O fumane lengolo la univesithi ea Vinnitsa State Medical. M.I. Pirogov le internship e thehiloeng ho eona.

Phihlelo: Ho tloha ka 2003 ho fihlela ka 2013, o ile a sebetsa e le morekisi oa meriana le mookameli oa k'hemiste ea meriana. O ile a fuoa mangolo le likhetho bakeng sa lilemo tse ngata tsa mosebetsi o hlokometsoeng ka hloko. Lingoloa tse mabapi le lihlooho tsa bongaka li ile tsa phatlalatsoa likhatisong tsa lehae (likoranteng) le liphatlalatsong tse fapaneng tsa inthanete.

Ke boetse ke sebelisa sethethefatsi se thehiloeng ho thioctic acid, se bitsoang Thioctacid BV. Ke laetsoe ke ngaka, khahlanong le semelo sa k'holeseterole e phahameng, le boima bo feteletseng. Nka re kamora libeke tse peli, boemo ba cholesterol bo ile ba fokotseha haholo. Ho phela hantle ha ka, boima ba 'mele bo ile ba qala ho fokotseha, mme le nna ke nkile qeto ea ho ea letamong, ka hona, ke ile ka qala bophelo bo botle.

Haeba aspartame e nkuoa ka lebaka la ho ts'oaroa, na ho ka khoneha ho nka acid ea thioctic?

Ngaka e ile ea mpolella hore ho bohlokoa ho qala ho nka moriana oa thioctic acid. Keletso efe?

Thioctic acid - ke eng

Ka 1951, thioctic acid (liphatlalatso: α-lipoic acid, vithamini N, Thioctic acid, thioctacid) e qalile ho arohanngoa le sebete sa nama, mme kamora likhoeli tse 10, e ile ea fumanoa.

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Hona le mehloli e 2 ea tlhaho ea ALA:

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Sena ke lijo. Vitamin N e fumanoa litapole, tomoso le sebete.
Tšimoloho ea tlhaho, ke hore, e entsoe ka microflora ea mala.

Motho ea phetseng hantle o hloka ligrama tse 1 ho isa ho tse peli ka letsatsi. thioctacide. Ho fihlela a le lilemo li 30, chelete ena e lekane litlhoko tsohle tsa 'mele. Lilemong tse latelang, ho hlokahala hore e phethe hape ka ho kenyelletsa lihlahisoa tse 'maloa tsa lijo lijong, joalo ka:

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lebese le lihlahisoa tsa lona,
mahe
Wheats groats
seqha
li-mushroom
meroho
maleatlana.

Phepelo e nepahetseng ea TC e ka khonahala ha feela ho fanoa ka lihlahisoa tse tsoang lenaneng lena, mme li lokela ho jeoa ka bongata. Ho bonolo haholo ho sheba meriana ea litlama.

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Mesebetsi ea biochemical

ALA ke coenzyme ea tlhaho (karolo eo e seng protheine ea li-enzyme) e ferekanyang oxidation ea lipids le lik'habohaedreite, tse hlahisang matla. Ts'ebetso tsena li tsoela pele ho li-membochondria - li-organelles tse khethehileng, tse bitsoang "liteishene tsa matla" tsa sele. Ka ts'ebetso ea eona, thioctacid e ts'oana le livithamini tsa sehlopha B.

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Thioctic acid e tlama li-radicals tsa mahala, e bonts'a thepa ea antioxidant. Ke 'nete ena hore lingaka tse thahasellang lefats'e ka bophara le monyetla o mocha oa ho phekola li-pathologies li thehiloe tlolong ea tekano ea oxidative-antioxidant. LC e hlophisa metabolism ea cellular ka ho kenya li-radicals tsa mahala ka kotloloho, li li hokahanya le lihlopha tsa SH ho tloha sebopeho sa tsona. E ts'ehetsa lits'ebetso tse ling tsa antioxidant 'meleng, li ka hlahisa litlamorao tse khahlanong le ho ruruha kamora ts'ebeliso ea lihormone tsa "hormone"

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E boetse e na le litlamorao tse ling tsa kalafo:

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activates metabolism ea matla, empa e thibela synthes ea cholesterol,
e tiisa litho tsa kahare tsa mmele,
e ntlafatsa phepo e nepahetseng ea lisele tsa methapo ea kutlo, e khothaletsa kholo ea axons (lits'ebetso tse telele),
e fokotsa tsoekere ea mali, ha e ntse e eketsa dikahare tsa glycogen ho hepatocytes,
e ntlafatsa ts'ebetso e sebetsang ea sebete,
e nts'etsapele ho chesoa hoa 'mele molemong oa ho chefo ka masenke a boima, mohlala, lead, mercury, chloride ea methapo le li-cyanides le phenothiazides,
e khahlanong le insulin,
e ntlafatsa mohopolo le maikutlo a kelello,
normalization mosebetsi oa manyeme, pelo, methapo ea mali, mohlahlobi oa pono.

Lisele tsa motho ALA li bonoa e le sehlahisoa sa tlhaho sa tlhaho. Ho na le mefuta e 'meli: oxidised le fokotsoa, ka lebaka la eona mesebetsi ea antioxidant le coenzyme e ka phethahala.

Vitamin N - karolo ea bohlokoa ea lithethefatsi tse fokotsang lipid le hepatoprotectors. Ho tloha bohareng ba lekholo la bo20 la lilemo, ka thuso ea bona, methapo ea pelo e thibetsoe, mafu a sa foleng a amanang le khatello ea oxidative, e leng a tloaelehileng a lefu la tsoekere.

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LC e amohetse kalafo ea hepatic pathologies. Litekong tsa liphoofolo, ts'ebetso ea eona ea ho fokotsa phepelo ea meriana e amanang le lefu la hepoto e netefalitsoe. Ho bontšoa bakeng sa tlhahlobo ea lefu la tsoekere la polyneuropathy (DPN). Ha e le antioxidant e matla e ananeloang e le "khauta e tloaelehileng" kalafong ea DPN, e fokotsa khatello ea kelello, paresthesia, le bohloko. Tsela ea tsamaiso: ka molomo kapa ka methapo, 600 mg ka letsatsi bakeng sa libeke tse 3-24.

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TK e kenella ka potlako ka mpeng ea gastrointestinal, e feta ka har'a sebete, empa lijo li mpefatsa tšebetso ena. Ka hona, bakuli ba fumana lithethefatsi tse nang le ALA halofo ea hora pele ho lijo hore ba boloke moriana ka botlalo.

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Liphuputsong tse ngata, bo-rasaense ba sebelisitse litekanyetso, khafetsa tšebeliso ea likhomphutha le vithamine N, le nako ea kalafo. Nakong ea e 'ngoe ea tsena, α-lipoic acid e ile ea fanoa ka methapo ho bakuli ba nang le matšoao a neuropathic bakeng sa libeke tse 3. Ka lebaka leo, ho boholo ba barupeluoa thutong, bohloko bo boholo bo ile ba kokobela.

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Thioctacid le ho feta boima ba 'mele

Kajeno, thioctic acid e khahla ba bangata e le sesebelisoa se sebetsang sa ho theola boima ba 'mele. O khona ho bulela "ho hasanya metabolism", ntle le tumellano e ke keng ea etsahala.

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Melemo ea thioctacide e kenyeletsa:

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Ho fokolloa ke takatso ea lijo joalo ka litlamorao tsa ts'ebeliso ea TC. Thusa ho koaloa ha lik'habohaedreite tse bonolo, ho susumetsa ho tsoa ha insulin, ho khutlisetsa tekano ea tsoekere le ho kenya ts'ebetso ea metabolism ea mafura. Li-LC li nkuoa ke batho ba lefu la tsoekere, 'me litlamorao li nkuoa li le molemo bakeng sa palo eo.
Ho amohela lipalo tse lekaneng tsa lipoate ho felisa ho hloka botsitso, matšoenyeho, a qetellang a felisang tlhokahalo ea ho hapa ho hloka thabo le khatello ea maikutlo.
Ho theola boemo ba ho tepella ka mmele ho u fa monyetla oa ho eketsa nako ea ho ikoetlisa, tlosa maikutlo a khatello ea maikutlo, ho ntlafatsa ts'ebetso ea lipapali le ho fihlella mohlala oa lipalo ka potlako.
Phokotso ea mafura a 'mele. Sena ha se bakoe ke ho chesoa ha lipids, empa ka lebaka la ts'ebetso ea oxidation e sebetsang ea lik'habohaedreite le thibelo ea ho etsoa ha lisele tsa subcutaneous, mehloli ea tsona e boetse e fokotsehile ka lebaka la tokollo ea liseleng tsa chefo, le ho se sebetse hoa metabolites.

Ka ho ja khafetsa matšoao a LC a otlolohileng, a tloaelehileng bakeng sa ho theola boima ba 'mele, u se ke oa theha.

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Litaelo tsa ho sebelisoa

Lithethefatsi li fana ka mefuta e 2 ea litekanyetso tsa TC:

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Matlapa a maputsoa a nang le 300 kapa 600 mg ea motsoako o sebetsang. Tekanyetso ea letsatsi le letsatsi e khothalletsoang ke tse peli tse nyane kapa tse 1. Ba lokela ho nooa halofo ea hora pele ho lijo tsa hoseng. Nako ea kalafo ke likhoeli tse 3 e le ts'ebetso ea tsamaiso ea batsoali nakong e fetang libeke tse 2-4.
Tsepamiso eo ho eona ho hlophisitsoeng lipina tsa infusion (ho 1 ml ea 30 mg ea TC). Litekanyetso li tšoana. Sebelisa tharollo e sa tsoa lokisoa. E bolokiloe lefifing, empa eseng ho feta lihora tse 6. Kenyelletso e lieha, in / in, drip. Nako ea libeke tse 2-4 le phetoho ea mofuta oa TC ea letlapa.

Litlhahiso tsa baetsi ba ALA le lingaka li kanna tsa se lumellane. Tsena tsa morao-rao li tataisoa ke molao oa "U se ke oa ntša kotsi!" 'Me u eletse:

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Khomarela tloaelo ea letsatsi le letsatsi, e lekanang le 50 mg. Ka kalafo ea methapo ea methapo, sebete le tsamaiso ea methapo ea pelo, e ka eketsoa ke ngaka ho ea ho 75 mg.
Ho lefu la tsoekere, ho bontšoa 400 mg ea TC.
Bakeng sa baatlelete ba amehang thupelong ea pelo, ho fihlela ho 500 mg.
Bakeng sa ho theola boima ba 'mele, empa batho ba phetseng hantle ka letsatsi, o ka nka bonyane 100 mg. Basali ho ea ka scheme: 3 × 10-15 mg, banna makhetlo a 2 ho feta.
Tekanyetso nakong ea ente ea methapo ea methapo e ke ke ea feta 50 mg. Bakeng sa ho qoba litlamorao tse matla, lenaneo la kamohelo boemong bo bong le bo bong le hlahisoa ke ngaka.
Nako ea thupelo e lekanyelitsoe ho libeke tse 2-3. Tšebeliso e tsoelang pele e baka kotsi bophelong. Nako e khuts'oane ke likhoeli tse peli.

Monko o khethehileng oa moroto ka mor'a ts'ebeliso e sebetsang ea litokisetso tsa TC ke ntho e tloaelehileng.

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Litlamorao

Ho nka lipilisi ho ka tsamaisana le litlamorao tse 'maloa, ho kenyelletsa:

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bohloko ba ka mpeng, lets'ollo,
allergy e nang le lipontšo tsa letlalo, ho ts'oaroa ha anaphylactic,
hypoglycemia, lits'ebetso tsa tlhahlobo ea pono, hlooho e bohloko, hyperhidrosis,
liphetoho tsa tatso.

Ha o sebelisa ho tsepamisa mohopolo, litla-morao li ama phallo ea mali le sebopeho sa mali. Ho ka etsahala hore ho be le lits'ila le ho tuka ho chesang, hammoho le ts'ebetso ea li-enzyme tsa sebete, tachycardia, thrombophlebitis.

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Ha moriana o qala ho tsebisoa ka potlako, mathata a ho hema a hlaha, 'me bofokoli boa tšoenyeha.

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Ho nka 10-40 g ea TC ho lebisa ho mokokotlo oa masapo, ho se sebetse hantle ha litho tse ngata, ho senyeha ha mali le ho leka-lekana ha electrolyte, tšenyo ea lisele tse khubelu tsa mali, lesapo la mokokotlo oa mokokotlo, ho ruruha ka kakaretso, komello ea hypoglycemic.

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Ha ho na letho le ka felisang chefo ea LC. Ka overdose e matla, ho pepesoa sepetlele ho bontšoa. Sepetlele, tlas'a tlhokomelo le taolo ea ngaka, bakuli ba fuoa meriana e tšehetsang mesebetsi ea 'mele.

Thioctic asiti, theko ka har'a k'hemiste, li-analogues

'Marakeng, lithethefatsi tse nang le TC li arotsoe ka lihlopha tse 3:

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Sehlopha sa 1. Mithethefatsi eo, ka ho se sebelise ho bala, e baka litlamorao tse mpe, ka hona ho molemo ho se e sebelise ho tlosa liponto tse eketsehileng. Har'a tse tummeng:

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Berlition.Setlhare se laolang lits'ebetso tsa metabolic. Sephutheloana sa litafole tse 30 se theko ho li-ruble tse 700, 'me theko ea li-ampoules tse 5 ho tloha ho 500 r.
Thiolipone. Antioxidant ea mofuta oa tlhaho ea tlhaho. Bakeng sa lithane tse 30, u tla tlameha ho lefa 800 r.
Thioctacid. Litsenyehelo tsa lithane tse 30 ho tloha 1800 p.
Espa Lipon. Molaoli oa Metabolic. E sebelisoa e le sesebelisoa kalafo ea lefu la tsoekere. Theko ea li-ampoules tse 5 ho tloha ho 750 p.
Oktolipen. Sethethefatsi se felisang ho beoa ha mafura. E hloka ho tloha ho 300 p.

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Sehlopha sa 2. Lifekthering, ho boetse ho na le thioctic acid e tloaelehileng (600 mg), theko ea letlapa ke li-ruble tse 50 bakeng sa likotoana tse 50. Li sebetsa ka mochine o ts'oanang 'me li sa sebetse hantle. Ka hona, pele u fumana li-analogues tse theko e boima, e ke ke ea e-ba ntho e se nang thuso ho tseba hore na sehlahisoa se secha se entsoe joang ebe u etsa qeto.

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Matlapa ha a lokela ho kopana le mongobo. Tsepamisa mohopolo bakeng sa ho hlophisoa ha litharollo li sirelelitsoe mahlaseling a tobileng a kotsi ea letsatsi. Lithethefatsi tse feliloeng, ho sa tsotelehe mofuta oa vithamine N ea ho lokolloa, li ka lebisa chefo. Pele u reka, etsa bonnete ba ho hlahloba hore na moriana o felloa ke nako neng, bala ka hloko litaelo.

3 sehlopha. Khetho e loketseng haholo, e sebetsang bakeng sa botena, ke litlatsetso tsa ho ja tse nang le thioctic acid. Mmaraka o fana ka mefuta e fapaneng ea mefuta e fapaneng. Kaofela ha tsona li ruisitsoe ka likarolo tse ling tsa bohlokoa tse sebetsang. Har'a tse tummeng:

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ALK ea Evalar. E fana ka ts'ireletso ea antioxidant le detoxification ea 'mele, e sireletsa sebete. Theko ea sehlahisoa e batla e le li-ruble tse 300 bakeng sa li-capsule tse 30 (100 mg ea motsoako o sebetsang). Melemo ea mohala oa Turboslim e tiisitsoe ke lingaka.
Matlapa a TK a tsoang Square-C ke mohloli o mong oa vithamine N. Ba fokotsa boima ba 'mele, ba potlakisa metabolism ea mafura,' me ba etsa hore boemo ba sesole sa 'mele bo fetohe. E mong le e mong ea sebeletsang o na le 30 mg ea motsoako o sebetsang. Theko ea pakete ea matlapa a 30 e qala ho 60 p.
Monyetla oa ho ba le bophelo bo botle, letlalo le letle le 'mele o fanang ka sethethefatsi e fana ka sethethefatsi le TC ho tsoa DHC - moetsi oa lisebelisoa tsa phepo ea Japane Theko ea sehlahisoa ke 1000 r. bakeng sa likhaba tse 40.
Sebopeho se se nang gluten se tsoang khamphaning ea Amerika Solgar se loketse lihlahisoa tsa meroho. Litsenyehelo tsa sephutheloana sa lithane tse 50 ke li-ruble tse 1,400.

Meriana e ka rekoa inthaneteng kapa ka har'a k'hemiste e tloaelehileng ka taelo ea ngaka. Lijo tse tlatsetsang ka tlung ea lijo tse nang le TC li rekisoa mabenkeleng a phepo e nepahetseng. Pele o nka tlhahlobo ea setsebi.

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Thioctic acid ke eng

Ha e nkoa ka molomo, asiti ea thioctic e qhibiliha kapele 'me e ajoa hohle' meleng. Phello e phahameng e ka fumaneha ka metsotso e 40-60. Lenane la bioavailability la lithethefatsi ke 30%.

Haeba mokuli a ente ka 600 mg ka methapo, phello e phahameng e hlaha kamora halofo ea hora. Moriba o tšeloa ka har'a sebete, mokokotlo oa mahlakoreng o na le oxidized, khokahano e qala. Moriana o khetholloa ke ketso ea karolo ea pele ka sebete. E tlosoa ka moroto ka 80-90%, halofo ea bophelo ke metsotso e 20-50. Bophahamo ba thomello ke 450 ml / kg. Tlhahiso ea Plasma e tsoa ho 10 ho isa ho 15 ml / min.

Thioctic acid e laetsoe polyneuropathy, e hlahisoang ke lefu la tsoekere kapa tšebeliso e mpe ea joala.

mmele ha o mamelle dikarolo,
basali ba baimana ha baa lokela ho noa nakong ea kemolo,
ha e ngoletsoe bana.

Bakuli ba lilemo tse kaholimo ho 75 ba kenella ka hloko.

Matlapa a nooa a felletse hoseng halofo ea hora pele a ja, a hlatsuoa ka metsi, a se ke a hlafuna. Hangata ho fanoa ka makhetlo a 600 mg 1 hang ka letsatsi. Matlapa a lumelloa ho nooa libeke tse 2 ka mor'a ho qala ha tsamaiso ea batsoali. Nako e telele ea kalafo ke libeke tse 12, ka mor'a moo ngaka e khethang tlhokahalo ea ts'ebeliso ea moriana hape.

Ha o sebelisa 10 ho isa ho 40 g ea moriana, matšoao a latelang a ho tahoa a hlaha:

Ntlafatso ea lefu la tsoekere - e-nooa feela letsatsi le leng le le leng.

cramps
hypoglycemic coma,
lactic acidosis,
mali ha a apere hantle
mesifa ea "scleral mesifa" ea senyeha.

Tharollo ea infusion e kenngoa kahare ka sekontiri ka lerotholi. U ka sebelisa li-ampoules tse peli ka letsatsi. Bakeng sa ho itokisetsa, ho sebelisoa sesebelisoa sa 250 ml sa 0.9% sa saline, se sebelisoang hang ka mor'a tlhahiso. Moriana o tlameha ho bolokoa hole le khanya ea letsatsi, ka hona o tla khona ho lelefatsa nako ea bophelo ba hae ba lishelefo ho fihlela lihora tse 6.

Lipoic acid

Setlhare sena se hlahisoa matlapeng a Russia - analogue e phethahetseng ea thioctic acid. E entsoe motheong oa karolo e tšoanang e sebetsang. E na le thepa ea antioxidant, e sireletsa lisele le litho ho tsoa liketsong tsa li-radicals tsa mahala, hape e tsosa phello ea hypoglycemic ea enjene ea maiketsetso kapa ea li-pancreatic enzymes. E ntlafatsa metabolism le ho monya ha lipids tsamaisong ea hepatic, e nolofatsa mosebetsi oa sebete.

Neuro lipone

E laeloa feela lefu la tsoekere kapa joala. Litaba tse felletseng:

E hlahisoa ka li-capsule tsa 600 mg ka mokhoa oa ntho e kopaneng, e sebelisetsoang ho theha mokelikeli bakeng sa infusion. Litla-morao - mathata a ts'ebetsong ea mali.

Ha e fuoe bakuli ba nang le mamello e fokolang ea galactose le batho ba haelloang ke lactase 'meleng.

Phekolo e nka libeke tse 2-4, kamora 'mele o bolokiloe likhoeli tse' maloa. Setsebi se hlakisa hore na ho na le tlhoko ea keketseho ea kalafo.

Motsoako ona o etsoa ke lik'hamphani tsa meriana tsa Russia. Oktolipen ke karolo ea sehlopha sa li-antioxidants tsa mehleng ea khale tse ka khothalletsang ho felisoa ha likarolo tse bokelletseng tsa mmele. Matšoao:

diabetesic polyneuropathy,
mathata le tsamaiso ea methapo ka lebaka la joala.

Octopylene ke analogue e felletseng ea Tiogamma. Molao-motheo oa ts'ebetso o ipapisitse le bokhoni ba ho laola bongata ba tsoekere le glycogen. Moriana o ntlafatsa metabolism, o ntlafatsa metabolism.

Re fana ka theolelo ho babali ba sebaka sa rona sa marang-rang!

E hlahisoa ka mokhoa oa li-capsules tsa 300 mg, matlapa a 600 mg mme e le ka sebopeho sa ntho e kopaneng, motheo oa tharollo bakeng sa li-droppers. Phekolo e joalo e etsoa feela sepetlele. Lithethefatsi li sebelisoa ka mokhoa o khutsitseng lapeng ho latela litaelo tsa endocrinologist.

Litla-morao kamora ho nka tlhahiso ea lapeng ea Octopylene li boleloa haholo ha li bapisoa le meriana ea Jeremane. Tšebeliso e kopanetsoeng le joala e thibetsoe, lihlahisoa tsa lebese le tsona li tla tlameha ho tloheloa bakeng sa nako ea phekolo.

Setlhare sa ka tlung, motsoako o ka sehloohong ke thioctic acid, e 'ngoe ea likarolo tse thusang ke oli ea teak.

Moriana o etsa mosebetsi oa ho sireletsa lisele ho li-radicals tse sebetsang, o ntlafatsa ts'ebetso ea sebete, o thusa ho fetisa litšusumetso haufi le methapo ea methapo.

Moriana o thusa ho laola tsoekere ea mali, ho senya cholesterol e ngata, le ho fetola metabolism ea lipid. Hora e le 'ngoe ka mor'a ts'ebeliso, bongata bo bongata ba likarolo tse sebetsang' meleng bo bonoa.

Matlapa a entsoe Jeremane, motsoako o ka sehloohong ke thioctic acid. Lintho tse ling:

Setlhare se fuoe li-hepatic pathologies le ho senyeha ha methapo ea methapo ka lebaka la lefu la tsoekere kapa joala. Setlhare se ntlafatsa ho kenngoa ha lisele tsa insulin, se lokisa boemo ba cholesterol maling. U ke ke ua e sebelisa bakeng sa basali ba baimana, bakuli ba nang le myocardial infarction, mafu a ka mpeng, mathata a pelo, sebete.

Naha ea tlhahiso - Jeremane. Karolo e ka sehloohong ke thioctic acid. Matšoao:

neuropathy
lefu la sebete
atherosulinosis
botaoa ba 'mele
mathata a metabolic.

E hlahisoa ka matlapa a 600 mg kapa ampoules ea liente tsa 25 mg / ml, moriana ona o sebelisoa ka mokhoa o nepahetseng. Ha u sebelisa matlapa, acid ea thioctic e ananeloa hamolemo, liente li nchafatsoa ka botlalo.

Thioctacid ke analogue e felletseng ea Thiogamm, e lumellana le eona litsobisong tsa pharmacological.

Tsena ke li-antioxidants tsa endo native tse nang le phello e molemo ho metabolism. Ho latela lipontšo tse ling, lithethefatsi li fapana, Thioacid e na le lipalo tse nyane haholo.

diabetesic polyneuropathy,
osteochondrosis.

Tlhahiso ea Jeremane, thepa eo boholo ba eona e kopanang le Thioctacid. E etselitsoe mathata a sebete, e sirelletsa 'mele chefo, e sebetsa joalo ka antioxidant, e thibela matšoao a chefo ea tšepe e boima. Litlamorao tsa li-plaque tsa methapo ea methapo methapong ea mali le tsona lia felisoa. Berlition e thusa ho laola boholo ba tsoekere le lipids.

Matlapa a 300 mg
ntho e kenelletseng molemong oa ho hlophisoa ha tharollo ho li-ampoules tsa 300 le 600 mg.

Bakuli ba bang ba na le mathata a dyspeptic kapa allergies ka tsela ea litla-morao, ka linako tse ling khatello ea kelello e kenella, 'me thempereichara e nyoloha.

Maikutlo a lingaka

Setlhare se na le thepa e ntle ea ho folisa. Ona ke mofuta oa bokahohleng oa neuroprotective le antioxidant. E ngotsoe ho batho ba lefu la tsoekere le bakuli ba nang le polyneuropathy.

Basali ba fuoa Thioctic acid bakeng sa tahlehelo ea boima ba 'mele, empa lingaka ha li lumellane ka katleho ea lithethefatsi bakeng sa phetoho ea boima ba' mele. Litsenyehelo tsa sesebelisoa se joalo li phahameng haholo.