Gliformin, matlapa a 1000 mg, 60 likhomphutha.

Ka kopo, pele u reka Gliformin, matlapa a 1000 mg, li-pc tse 60. Lekola tlhaiso-leseling e mabapi le eona le tlhahisoleseling ho websaeteng ea semmuso ea moetsi kapa hlakisa lintlha tse ikhethang tsa mofuta o itseng le molaoli oa k'hamphani ea rona!

Tlhahisoleseling e bontšitsoeng sebakeng sena sa marang-rang hase tlhahiso ea sechaba. Moetsi o na le tokelo ea ho etsa liphetoho moralo, moralo le liphutheloana tsa thepa. Litšoantšo tsa thepa tse lifoto tse hlahisitsoeng lethathamong la sebaka sa marang-rang li ka fapana le tsa pele.

Tlhahisoleseling mabapi le theko ea thepa e bontšitsoeng lethathamong la sebaka sa marang-rang e kanna ea fapana ka nako ea ho beha odara bakeng sa sehlahisoa se tsamaellanang.

Ketso ea pharmacological

Gliformin ke moemeli oa hypoglycemic bakeng sa tsamaiso ea molomo ea sehlopha sa Biguanide. Glyformin e thibela gluconeogenesis ka har'a sebete, e fokotsa ho monya ha glucose mala, e ntlafatsa tšebeliso ea glucose, hape e eketsa kutloisiso ea lithane ho insulin. Leha ho le joalo, ha e ame sephiri sa insulin ke lisele tsa beta tsa manyeme. Fokotsa boemo ba triglycerides le lipoprotein tse tlaase maling. E tsitsisa kapa e theola boima ba 'mele. E na le phello ea fibrinolytic ka lebaka la khatello ea inhibitor ea tisy ea plasminogen activator.

Type 2 lefu la tsoekere mellitus (haholo ho bakuli ba nang le botenya) le ho hloleha ha kalafo ea phepo.

Bokhachane le pelehi

Sebelisa nakong ea bokhachane le nakong ea ho anyesa (sefuba) e tšoaetsanoa. Ha u rera ho ima, hammoho le ketsahalong ea kemolo ha u ntse u nka Gliformin, moriana o lokela ho khaotsa mme kalafo ea insulin e lokela ho fanoa. Ha ho tsejoe hore na metformin e pepesitsoe lebeseng la matsoele, ka hona Glyformin® e tšoaelitsoe ho anyesa. Haeba ho hlokahala ho sebelisa moriana o bitsoang Glyformin® nakong ea lebone, letsoele le lokela ho emisoa.

Contraindication

• lefu la tsoekere ketoacidosis, lefu la tsoekere, leta,
• khathatso e matla ea renal,
• ho nyekeloa ke pelo le ho hema ka matla, mokokotlo o matla oa ho ruruha ha methapo ea pelo, ho senyeha ha methapo ea pelo, ho felloa ke metsi, ho lemalla joala bo sa foleng le maemo a mang a ka kenyang kholisong ea lactic acidosis,
• ho ima le ho nyekeloa,
• hypersensitivity ho lithethefatsi,
• ho buuoa ka matla le ho tsoa likotsi ha ho bontšoa kalafo ea insulin,
• ho se sebetse hantle ha sebete, chefo e matla ea joala,
• lactic acidosis (ho kenyeletsoa le nalane),
• sebelisa bonyane matsatsi a 2 pele le ka nako ea matsatsi a mabeli kamora ho etsa lithuto tsa radioisotope kapa x-ray ka tlhahiso ea iodine e nang le phapang e mahareng.
• ho khomarela lijo tse nang le khalori e tlase (ka tlase ho likhalori tse ka tlase ho 1000 / letsatsi).

Ha ho khothalletsoe ho sebelisa lithethefatsi ho batho ba lilemo tse fetang 60 ba etsang mosebetsi o boima oa 'mele, o amanang le kotsi e kholo ea ho ba le lactic acidosis ho bona.

Litlamorao

Ho tsoa ho tsamaiso ea tšilo ea lijo: ho nyekeloa ke pelo, ho hlatsa, "mokhoa oa" metallic "ka hanong, ho hloka takatso ea lijo, lets'ollo, lefutso, bohloko ba ka mpeng.
Ho tloha lehlakoreng la metabolism: maemong a sa tloaelehang - lactic acidosis (e hloka ho khaotsa kalafo), ka kalafo ea nako e telele - hypovitaminosis B12 (malabsorption).
Ho tsoa lithong tsa hemopoietic: maemong a mang - anemia ea megaloblastic.
Ho tsoa ho sistimi ea endocrine: hypoglycemia (ha e sebelisoa ka tekanyetso e sa lekanang).
Litla-morao:

Tšebelisano

Ka tšebeliso e le 'ngoe le metsoako ea sulfonylurea, acarbose, insulin, lithethefatsi tse seng khahlanong le' mele tse thibelang mafu, monoamine oxidase inhibitors, oxytetracycline, angiotensin e fetolang li-enzyme inhibitors, li-exofibrate tse tsoang, cyclophosphamide, beta-adrenergic agents. Ka tšebeliso e ts'oanang le glucocorticosteroids, lithibela-pelehi tsa molomo, epinephrine, sympathomimetics, glucagon, lihomone tsa qoqotho, thiazide le "loop" diuretics, melemo ea phenothiazine, li-derivatives tsa nicotinic, ho ka khoneha ho fokotsa phello ea hypoglycemic ea Glyformin®.
Cimetidine e liehisa ho felisoa ha Glyformin®, e lebisang kotsing e eketsehileng ea lactic acidosis.
Glyformin® e ka fokolisa phello ea li-anticoagulants (tse tsoang ho coumarin). Ka joala bo bongata ka nako e tšoanang, nts'etsopele ea lactic acidosis e khonahala.

Mokhoa oa ho nka, oa tsamaiso le litekanyetso

Tekanyo ea lithethefatsi e beoa ke ngaka ka bonngoe, ho latela boemo ba tsoekere maling.
Motsoako oa pele ke 0.5-1 g / ka letsatsi. Kamora matsatsi a 10-15, keketseho e tsoelang pele ea butle-butle ea tekanyetso e khonahala ho latela boemo ba glycemia. Tekanyetso ea litlhare ea moriana hangata ke 1.5-2 g / ka letsatsi. Tekanyo e phahameng ke 3 g / ka letsatsi. Ho fokotsa litla-morao tse tsoang mpeng ea gastrointestinal, tekanyetso ea letsatsi le letsatsi e lokela ho aroloa ka litekanyetso tse peli. Ho bakuli ba tsofetseng, tekanyetso ea letsatsi le letsatsi e khothalletsoang ha ea lokela ho feta g. Matlapa a Glyformin ® a lokela ho nkuoa a felletse nakong ea lijo kapa hang ka mor'a lijo le metsi a mangata (khalase ea metsi). Ka lebaka la kotsi e eketsehang ea lactic acidosis, tekanyo ea Glyformin ® e tlameha ho fokotsoa ho ts'oenyeho e matla ea metabolic.

Bongata

Tabeng ea overdose ea Glyformin®, lactic acidosis e ka hlaha. Sesosa sa nts'etsopele ea lactic acidosis le eona e ka ba ho bokellana ha moriana ka lebaka la ts'ebetso ea renal e sa sebetseng. Matšoao a pele a lactic acidosis ke ho nyekeloa pelo, ho hlatsa, lets'ollo, feberu, bohloko ba ka mpeng, bohloko ba mesifa, mme ho ka ba le ho hema ka potlako, ho tsekela, ho akheha kelellong le ho holofala.
Phekolo: Haeba ho na le matšoao a lactic acidosis, kalafo e nang le Glformin® e lokela ho emisoa hang-hang, mokuli o lokela ho kena sepetlele ka potlako mme ha a se a lemohile hore o na le lactate, o netefatsa tlhahlobo eo. Mohato o sebetsang ka ho fetisisa oa ho tlosa lactate le Glformin® 'meleng ke hemodialysis. Phekolo ea matšoao le eona ea etsoa. Ka kalafo e kopaneng ea Gliformin® e nang le litokisetso tsa sulfonylurea, hypoglycemia e ka hlaha.

Litaelo tse ikhethang

Nakong ea kalafo, ho hlokahala hore ho hlahlojoe ts'ebetso ea renal. Bonyane makhetlo a mabeli ka selemo, hammoho le ponahalo ea myalgia, litaba tsa lactate tse ho plasma li lokela ho ikemisoa.
Glyformin® e ka sebelisoa hammoho le lintlha tse tsoang ho sulfonylurea. Maemong ana, ho hlokahala haholo ho lekola maemo a tsoekere ea mali.