Matšoao a ts'ebeliso le litaelo tsa tšebeliso ea lithethefatsi Dibikor
Nomoro ea ngoliso: P N001698 / 01
Lebitso la Khoebo la tokiso: Dibicor ®
Lebitso la machaba le sa ameheng: taurine
Foromo ea litekanyetso: matlapa
SebopehoLetlapa le 1 le na le:
ntho e sebetsang:
- taurine 250 mg
excipients: microcrystalline cellulose 23 mg,
litapole starch 18 mg, gelatin 6 mg, colloidal silicon dioxide
(aerosil) 0,3 mg; khalsiamo e theohile ka 2.7 mg. - taurine 500 mg
excipients: microcrystalline cellulose 46 mg,
litapole starch 36 mg, gelatin 12 mg, colloidal silicon dioxide
(aerosil) 0,6 mg; khalsiamo e bohale 5.4 mg.
Tlhaloso: matlapa a mmala o mosoeu kapa o batlang o le mosoeu, o chitja, o sephara-cylindrical, o nang le kotsi le tšobotsi.
Sehlopha sa Pharmacotherapeutic: moemeli oa metabolic.
Khoutu ea ATX: C01EB
TLHALOSO YA PHARMACOLOGICAL
Mofumahali
Taurine ke sehlahisoa sa tlhaho sa phapanyetsano ea li-amino acid tse nang le sebabole: cysteine, cysteamine, methionine. Taurine e na le thepa e sireletsang ea "membrane" le "membrane-kinga", e ama hantle phapang ea phospholipid ea membrane ea lisele, hape e tloaetse phapanyetsano ea calcium le potonium ions ka liseleng. Taurine e na le thepa ea neurotransmitter ea inhibitory, e na le phello ea antistress, e ka laola ho lokolloa ha gamma-aminobutyric acid (GABA), adrenaline, prolactin le lihormone tse ling, hammoho le ho sebetsana le likarabo ho tsona. E nka karolo mofuteng oa liprotheine tsa phepelo ea phefumoloho ho mitochondria, taurine e laola lits'ebetso tsa oxidative mme e bonts'a thepa ea antioxidant, e ama li-enzymes tse kang cytochromes tse amehang metabolism ea li-xenobiotic tse fapaneng.
Phekolo ea Dibicor ® bakeng sa pelo le ho hloka methapo ea pelo (CCH) e lebisa ho fokotseha ha khatello ea methapo tsamaisong ea mali le methapo ea mali: khatello ea methapo ea methapo ea methapo e fokotseha, ho eketseha ha sekhahla sa myocardial (tekanyo e phahameng ea phokotso le phomolo, konteraka le konopo ea phomolo).
Mokhoa oa lithethefatsi o theola khatello ea mali ka mokhoa o itekanetseng (BP) ho bakuli ba nang le khatello ea mali ea methapo 'me ha o ame khatello ea mali ho bakuli ba nang le lefu la pelo le khatello e tlase ea mali. Dibicor ® e fokotsa litla-morao tse bang teng ka bongata ba pelo le li-blockter tsa "calcium" tse liehang "ho fokotsa boima ba lithethefatsi tse thibelang hepatotoal." E eketsa ts'ebetso nakong ea ho ikoetlisa ka matla.
Ho tsoekere ea lefu la tsoekere, hoo e ka bang libeke tse peli kamora ho qala ho nka Dibicor®, khatello ea tsoekere maling e ea fokotseha. Ho fokotseha ho hoholo ha khatello ea "triglycerides", ho isa tekanyong e nyane, khatello ea cholesterol, ho fokotseha ha atherogenicity ea lipids tsa plasma, le eona e hlokometsoe. Ka tšebeliso ea nako e telele ea lithethefatsi (likhoeli tse ka bang 6)
ho ntlafatsa phallo ea mali e tsoang ka leihlong.
Mofumahali
Kamora tekanyetso e le 'ngoe ea 500 mg ea Dibicor, taurine e sebetsang ea taurine ka metsotso e 15-20 e khethiloe maling.
ho fihla holimo kamora lihora tse 1.5-2. Setlhare se hlakoloa ka botlalo ka letsatsi.
Matšoao a sebeliso:
- ho se sebetse hantle ha pelo ha methapo e mengata ea maikutlo,
- cardiac glycoside botahoa,
- mofuta oa 1 lefu la tsoekere
- mofuta oa 2 lefu la tsoekere, ho kenyeletsa le hypercholesterolemia e leka-lekaneng,
- e le hepatoprotector ho bakuli ba noang lithethefatsi tse thibelang mahlo.
Sokolla foromo le sebopeho
E fumaneha matlapeng: li-flat-cylindrical, tse tšoeu kapa tse batlang li le tšoeu, li na le kotsi le bevel (250 mg e ngoe le e 'ngoe ka lipaketeng tse 10 tse nang le lithutsoana, ka pakete ea likarete tse 3 kapa tse 6, likotoana tse 30 kapa 60 ka har'a linkhoana tsa khalase tse lefifi, ka pakete ea karete ea 1 e ka khonehang, 500 mg - likotoana tse 10 ho e ngoe le e ngoe ka lipaketeng tse nang le lithutsoana, ka pakete ea likarete tse tharo kapa tse 6.
Lintho tse sebetsang: taurine, letlapeng le le leng - 250 kapa 500 mg.
Likarolo tse thusang: starch ea litapole, cellcose ea microcrystalline, calcium stearate, colloidal silicon dioxide (aerosil), gelatin.
Mofumahali
Taurine - ntho e sebetsang ea Dibikor - sehlahisoa sa tlhaho sa phapanyetsano ea li-amino acid tse nang le sebabole: cysteamine, cysteine, methionine. E na le ts'ebetso ea ts'ireletso ea osmoregulatory le membrane, e na le phello e ntle sebopeho sa phospholipid ea membrane ea lisele, mme e thusa ho fetofisa phapanyetsano ea potasiamo le calcium ions ka liseleng.
E na le thepa ea neurotransmitter ea inhibitory, e na le antioxidant le antistress athari, e laola ho lokolloa ha GABA (gamma-aminobutyric acid), prolactin, adrenaline le lihormone tse ling, hammoho le likarabo ho tsona. E nka karolo mofuteng oa liprotheine tsa phepelo ea methapo ho mitochondria, ho hlokahala lits'ebetsong tsa oxidative, mme e ama li-enzyme tse ikarabellang bakeng sa metabolism ea li-xenobiotic tse fapaneng.
Ho bakuli ba nang le lefu la tsoekere, hoo e ka bang libeke tse peli kamora ho qala kalafo, ho bonoa ho fokotseha hoa maemo a tsoekere ea mali. Ho bile le phokotseho e kholo khoebong ea li-triglycerides, ho isa tekanyong e nyane haholo - atherogenicity ea plasma lipids, cholesterol level. Nakong ea thupelo e telele (hoo e ka bang likhoeli tse tšeletseng), ntlafatso ea phallo ea mali ea leihlo le nchocho e bonoa.
Liphello tse ling tsa Dibikor:
- ntlafatso ea lits'ebetso tsa metabolic ka har'a sebete, pelo le lisele tse ling le litho,
- phallo ea mali le ho fokotsa ho teba ha cytolysis ka lebaka la mafu a sa foleng a amanang le sebete,
- Phokotso ea khoholeho meralong e meholo / e meholo ea potoloho ea mali ka ho se sebetse hantle ha pelo, e iponahatsang ka mokhoa oa ho fokotseha ha khatello ea methapo ea methapo ea methapo, ho eketseha ha konteraka ea myocardial,
- fokotseha ha hepatotoxicity ea lithethefatsi tsa antifungal ka ts'ebeliso e kopaneng,
- phokotso e leka-lekaneng ea khatello ea mali le khatello ea mali ea methapo, ha ho bakuli ba nang le lefu la pelo le boemo bo tlase ba khatello ea mali, phello ena ha e eo,
- fokotseha ho teba ha mekhoa e mebe e bakiloeng ke ho ata ha methapo ea pelo le li-blockers tse liehang ho feta tsa calcium,
- ho eketsa ts'ebetso nakong ea ho ikoetlisa ka matla.
Litaelo tsa ho sebelisa Dibikora: mokhoa le litekanyetso
Dibicor e lokela ho nkuoa ka molomo.
Melao ea kalafo e khothalelitsoeng ho latela lipontšo:
- Ho hloleha ha pelo: makhetlo a 250-500 mg makhetlo a 2 ka letsatsi metsotso e 20 pele ho lijo, nako ea kalafo ke bonyane matsatsi a 30. Haeba ho hlokahala, tekanyetso ea letsatsi le letsatsi e eketsoa ho 2000-3000 mg,
- Phekolo ea pelo ea pelo: bonyane 750 mg ka letsatsi,
- Mofuta oa 1 lefu la tsoekere: 500 mg makhetlo a 2 ka letsatsi hammoho le insulin. Nako ea kalafo ke likhoeli tse 3-6,
- Mofuta oa lefu la tsoekere la mofuta oa 2: makhetlo a 500 mg ka letsatsi e le setheo se le seng kapa se kopantsoe le li-agents tse ling tsa molomo.
- E le sethethefatsi sa hepatoprotective: 500 mg makhetlo a 2 ka letsatsi bakeng sa nako eohle ea ts'ebeliso ea li-antifungal agents.
Ho sebelisana le lithethefatsi
Taurine e ntlafatsa phello ea bokhoni ba glycosides ea pelo.
Haeba ho hlokahala, Dibicor e ka sebelisoa hammoho le lithethefatsi tse ling.
Litaba tsa Dibikor ke: Taufon, bolelele ba ATP, Tauforin OZ, Tincture ea hawthorn, ATP-Forte, Vazonat, Ivab-5, Kapikor, Karduktal, Cardioactive Taurin, Mexico, Metamax, Metonat, Mildrocard, Milkardin, Neocardilok, Rimodok , Tricard, Trizipin, Trimet, Vazopro, Mildrazin, Mildronat.
Litlhahlobo tsa Dibicore
Ho latela maikutlo, Dibikor ke sesebelisoa se theko e tlase ebile se sebetsang. Li bontša hore moriana o na le mamello e ntle, o etsa tsoekere kapele, o thusa ho eketsa ts'ebetso, ho ntlafatsa mohopolo le ho phela hantle. Bakuli ba bang ha ba thabele boholo ba lipilisi, tse ba thatafalletsang ho li metsa.
Tekanyetso le tsamaiso
Matlapa a Dibicor a nooa ka molomo pele ho lijo (hangata metsotso e 20 pele ho lijo tse reriloeng). Li lokela ho nkuoa li felletse ntle le ho hlafuna le ho noa metsi a mangata. Litekanyetso tsa moriana li latela ts'ebetso ea methapo ea mmele "
- Ho nyekeloa ke pelo - makhetlo a 250 kapa 500 mg makhetlo a 2 ka letsatsi, haeba ho hlokahala, litekanyetso li ka eketsoa ho 1-2 g (1000-2000 mg) ho litekanyetso tse 'maloa. Nako ea kalafo e joalo e hlahisoa ke matšoao a ho hloleha ha pelo, ka karolelano, ke matsatsi a 30.
- Mofuta oa 1 oa lefu la tsoekere mellitus (motho ea itšetlehileng ka insulin) - matlapa a nkuwa le motsoako o tlamang oa kalafo ea insulin ka tekanyetso ea 500 mg makhetlo a 2 ka letsatsi, nako ea kalafo e ka ba likhoeli tse tharo ho isa ho likhoeli tse tšeletseng.
- Mofuta oa lefu la tsoekere la mofuta oa 2 mellitus (o sa ts'epeng insulin) - 500 mg makhetlo a 2 ka letsatsi e le monotherapy kapa hammoho le lithethefatsi tse ling tse theolelang tsoekere. Ka tekanyetso e tšoanang, matlapa a Dibicor a sebelisetsoa lefu la tsoekere le keketseho e leka-lekaneng ea cholesterol ea mali (hypercholesterolemia). Nako ea kalafo e khethoa ke ngaka ka bonngoe, ho latela maemo a laboratori ea carbohydrate le lipid metabolism.
- Phekolo ea cardiac glycoside - 750 mg ka letsatsi bakeng sa litekanyetso tse peli.
- Thibelo ea hepatitis ea lithethefatsi tse nang le chefo ha u sebelisa lithethefatsi tsa antifungal - 500 mg makhetlo a 2 ka letsatsi nakong eohle ea tsamaiso ea bona.
Maemong a mangata, nako ea kalafo ka moriana ona e khethoa ke ngaka e le 'ngoe ka bo eona.
Litlamorao
Ka kakaretso, matlapa a Dibicor a mamelletsoe hantle. Ka nako e 'ngoe ho ka etsahala hore ho hlahe lintho tse kulang ka ho hlahisa matšoao letlalong ka mokhoa oa lekhopho, ho hlohlona kapa hives (lekhopho le sarolohang le shebahalang joalo ka ho chesoa ha nettle). Litla-morao tse matla (angioedema Quincke edema, anaphylactic shock) kamora ho nka moriana li e-so hlalosoe.
Litaelo tse khethehileng
Bakeng sa matlapa a Dibicor, ho na le litaelo tse 'maloa tse ikhethang tseo u lokelang ho li ela hloko pele u qala ts'ebeliso ea tsona:
- Khahlano le semelo sa ho arolelana le pelo glycosides kapa li-blockchain tsa calcium calcium, litekanyetso tsa matlapa a Dibicor li lokela ho fokotsoa makhetlo a ka bang 2, ho latela kutloelo-bohloko ea mokuli ho lithethefatsi tsena.
- Setlhare se ka sebelisoa hammoho le lithethefatsi tsa lihlopha tse ling tsa meriana.
- Ha ho na data mabapi le polokeho ea matlapa a Dibicor mabapi le ngoana ea ntseng a hola nakong ea kemolo kapa lesea nakong ea ho anyesa, ka hona, maemong ana, tsamaiso ea bona ha e khothalletsoe.
- Lithethefatsi ha li ame lebelo la maikutlo a psychomotor kapa monyetla oa ho imeloa.
Lifekthering, lithethefatsi li fanoa ntle le taelo ea ngaka. Haeba u belaela kapa u botsa lipotso ka tšebeliso ea matlapa a Dibicor, etela ngaka ea hau.
Contraindication
Hypersensitivity ho lithethefatsi. Tlas'a lilemo tse 18
(katleho le polokeho ha e a theoa).
Sebelisa nakong ea bokhachane le nakong ea ho anyesa
Ha ho khothalletsoe ho sebelisa lithethefatsi nakong ea kemolo le nakong ea
ho anyesa ka lebaka la ho hloka tsebo ea bongaka
ts'ebeliso mokhahlelong ona oa bakuli.