Litlhahlobo mabapi le Berlition 300

Matlapa a koahetsoeng ka filimi pota, biconvex, mmala o mosehla, o nang le notch ka lehlakoreng le leng, pono e tšekaletseng: bokaholimo bo sa lekanang ba 'mala oa mosehla o bobebe.

1 tab
thioctic asiti	300 mg

Baeti: lactose monohydrate - 60 mg, croscarmellose sodium - 24 mg, colloidal silicon diode - 18 mg, microcrystalline cellulose - 165 mg, povidone (K-30) - 21 mg, magnesium stearate - 12 mg.

Sebopeho sa Shell: Opadry OY-S-22898 mosehla - 12 mg (hypromellose - 6.597 mg, titanium dioxide (E171) - 3.9134 mg, sodium lauryl sulfate - 0,7096 mg, parafini ea metsi - 0,676 mg, dae ea quinoline e mose (E104) -0.075 mg, letsatsi le chaba ka dae mosehla (E110) - 0,029 mg, parafini e nang le metsi - 3 mg).

Li-pcs tse 10 - lithutsoana (3) - lipakete tsa karete.
Li-pcs tse 10 - lithutsoana (6) - lipakete tsa karete.
Li-pcs tse 10 - marang-rang (10) - lipakete tsa karete.

Ketso ea pharmacological

Thioctic (α-lipoic) asiti, e leng endo native antioxidant (e kopanyang li-radicals tsa mahala), e thehoa 'meleng nakong ea oxidative decarboxylation ea li-acid tsa α-keto. Ha e le coenzyme ea mitochondrial multenzyme complexes, e nka karolo ho oxidative carboxylation ea pyruvic acid le α-keto acid.

E thusa ho fokotsa tsoekere ea mali le ho eketsa litaba tsa glycogen bokong, hammoho le ho hlola khanyetso ea insulin. Ka mofuta oa ts'ebetso ea biochemical, e haufi le livithamini tsa B. E nka karolo taolong ea metabolism ea lipid le carbohydrate, e matlafatsa metabolism ea cholesterol, mme e ntlafatsa ts'ebetso ea sebete.

E na le hepatoprotective, hypolipidemic, hypocholesterolemic, hypoglycemic effect.

Mofumahali

Ho rekisa le ho tsamaisa

Kamora ho tsamaisoa ka molomo, asiti ea thioctic (α-lipoic) e potlakisa ebile e kenella ka botlalo ho tsoa ho tšilo ea lijo. Ho ja haholo ho fokotsa lijo. Nako ea ho fihla C_max - 40-60 metsotso Bioavailability ke 30%.

V_d - boholo ba 450 ml / kg.

Metabolism le excretion

E na le phello ea "mokhoa oa pele" ka sebete. Ho thehoa ha metabolites ho etsahala ka lebaka la oxidation ea lehlakore le thipa.

Thioctic acid le metabolites ea eona li kentsoe moroto (80-90%). T_1/2 - Metsotso e 20-50 Tlhahiso ea plasma ka botlalo ke 10-15 ml / min.

Litaelo tse khethehileng

Tharollo ea moriana e lokela ho sireletsoa ho pepesetsoa leseli, mohlala, sebelisa foil ea aluminium. Tharollo e sirelelitsoeng ke khanya e ka bolokoa nako e ka bang lihora tse 6. Bakuli ba nang le lefu la tsoekere ba hloka ho lula ba shebiloe tsoekere e maling, haholo-holo ha ba qala kalafo. Maemong a mang, ho hlokahala ho fokotsa tekanyetso ea insulin kapa sethethefatsi sa hypoglycemic bakeng sa ho qoba nts'etsopele ea hypoglycemia.

Bakuli ba nkang sethethefatsi Berlition 300 ba lokela ho hana ho noa joala.

Ho sebelisana le lithethefatsi

In vitro, thioctic (α-lipoic) acid e sebelisana le li-complexes tsa ionic tsa tšepe (mohlala, cisplatin). Ka hona, ka tsamaiso e le 'ngoe, ho fokotseha ha phello ea sisplatin ho ka etsahala.

Kamora ho nka Berlition 300 hoseng, ho kgothaletswa ho sebelisa lihlahisoa tsa tšepe, le magnesium, le lebese (ka lebaka la khalori ea tsona ea khalsiamo) kamora lijo tsa motšeare kapa ka shoalane.

Ka tšebeliso e tšoanang ea ethanol le metabolites ea eona li ka fokotsa ts'ebetso ea kalafo ea thioctic (α-lipoic) acid.

Ka tšebeliso e tšoanang ea Berlition 300 e eketsa phello ea hypoglycemic ea li-insulin le li-agent tsa hypoglycemic tsa molomo.

Sebopeho le sebopeho sa moriana

Alpha-lipoic acid e le karolo e sebetsang e hlahisoa ho Berlition ea lithethefatsi, e entsoeng ke k'hamphani ea litlama Chemie (Jeremane).

Setlhare ke sa sehlopha sa hepatoprotectors, li-agents bakeng sa kalafo le ho hlokomela mesebetsi ea sebete.

Ho ea ka mofuta oa tokollo, setlhare se hlahisoa:

Kameho e tebileng bakeng sa ho hlophisoa ha tharollo ea ente - ampoules 12 mg, e nang le alpha-lipoic acid e nang le 300 mg (UNITS). E kentsoe li-ampoules tse 5.10.15 ka lebokoseng la karete.
Ka har'a mohopolo bakeng sa ho hlophisoa ha tharollo ea ente, ho na le li-ampoule tse 24 mg tse nang le lethathamo la motsoako o ka sehloohong oa alpha lipoic acid ea 600 mg (UNITS). E kentsoe li-ampoule tse 5 kapa tse 10 ka lebokoseng la karete.
Ka li-capsules tse bonolo tsa gelatin bakeng sa tsamaiso ea molomo - 300 mg ea alpha-lipoic acid. E pakiloe ka foromo ea li-contour mesh le lebokose la karete.

Setsi se amanang le lifoto:

Matšoao a ho sebelisoa

Lithethefatsi li fanoa ka mokhoa oa kalafo ea adjunctive e le ho potlakisa metabolism ea matla, ho ntlafatsa lisele tsa trophic, ho etsa hore mmele o lekanye mmele le ho leka-lekana ha lipid 'meleng.

Berlition (alpha lipoic acid) e bonts'itsoeng:

liphetoho tsa atherosselotic likepeng tsa coronary,
phokolo ea mali
hypotension
ka methapo ea lesapo la mokokotlo le lefutso,
Ho taoa ho matla le ho sa foleng hoa lisosa tse sa tšoaneng (ho chefo ka letsoai la litšepe tse boima, chefo, joala),
polyneuropathies ea mabelo a holimo le a tlase (ho ruruha, chefo, allergic, ho sithabetsa, lefu la tsoekere, autonomic),
Ho senyeha hoa tlhaho ho lisele tsa bokong le mokokotlong,
endocrine pathologies e amanang le mathata a metabolic.

Contraindication

Berlition ea lithethefatsi e na le likhohlano.

Ka tlhokomeliso, tlasa taolo ea glycemic, setlama se nang le acid sa acid se ngoletsoe bakuli ba nang le lefu la tsoekere leha e le lefe.

Berlition ha e fuoe kalafo kalafong ea bana, basali nakong ea kemolo, ho beleha.

Meriana e thehiloeng ka alpha-acid e nang le acid e thibetsoe 'me ha e sebelisoe ho batho ba nang le bothata ba ho se mamellane ha fructose, khaello ea lactose, galactosemia.

Thepa ea lehlakoreng

Berlition e lokela ho sebelisoa feela kamora ho khothaletsoa kapa ho khethoa ha ngaka.

Berlition ka kakaretso e mamelloa hantle. ke bakuli. Litla-morao li ka ba maemong a sa tloaelehang, a feteletseng.

Ke matšoao afe a ka bonts'ang litla-morao tsa lithethefatsi tse thehiloeng ho alpha lipoic acid:

dyspepsia: ho nyekeloa ke pelo ka ho hlatsa, lets'ollo, ho qhekella, ho opeloa ke pelo ho epigastrium,
tatso e fetotsoeng
hlooho e bohloko, ho tsekela, ho ikutloa eka o boima hloohong, ho hlohlona, ho sitisoa hoa pono ka sebopeho sa lintsintsi tse benyang, ho iketla ha lintho,
liponahatso tse kholisang, ho thothomela hoa liphello,
mafu a pelo a mofuta oa hyperemia ea letlalo, maikutlo a ho ba le mathata a mangata, tachycardia,
allergic lipontšo tsa vv ka mokhoa oa rashes, ho hlohlona ha letlalo le urticaria.

Tekanyetso le overdose

Nako ea kalafo e nka likhoeli tse ka bang peli.

Tekanyetso le mokhoa oa tsamaiso ea litlhare Berlition o khethoa ke ngaka ka bonngoe.

Ka tloaelo, Berlition e fanoa ka molomo ka tekanyetso ea li-unit tse 600 hang bakeng sa kalafo ea polynyropathies hang pele ho lijo tsa hoseng.

Bakeng sa mafu a matla, joalo ka kalafo ea adjunct, ts'ebeliso e kopaneng ea lithethefatsi Berlition e bonts'oa: ente ea li-capsules.

Tharollo ea Berlition e fanoa ka methapo (likarolo tse 300 kapa tse 600) bakeng sa beke e le 'ngoe ho isa ho tse peli hoseng.

Sebopeho sa moriana bakeng sa ente ke ntho e kenelletseng, eo pele ho tsamaiso e kenngoeng ka letsoai la 'mele ka bongata ba 250 ml (vial).

Tharollo ea Berlition e tsamaisoa ka mokhoa o kenang kahare ka kotlolloho (metsotso e 30-45). Nakong ea entevenous drip ea ente, vial ea moriana e qhibilihileng e koetsoe ka pampiri e lefifi ea opaque kapa foil.

Kamora ho fokotseha ha lingaka, ngaka e beha ts'ebetso e eketsehileng ea lithethefatsi ka alpha-lipoic acid (ka molomo, likhabapo).

Likokoana-hloko tsa Berlition 300 U li ka fanoa ka intramuscularly bakeng sa libeke tse 2-4. Maemong ana, mohopolo oa lithethefatsi o hlapolotsoe ho 2 ml ea saline ea mmele.

Tsela ea teraria ka Berlition hangata e nka likhoeli tse peli. Ho ea ka bopaki, khoso ea bobeli ea kalafo ka moriana o thehiloeng ho alpha-lipoic acid e fanoe kamora likhoeli tse tšeletseng.

Setlhare se fetang tekano sa lithethefatsi tse nang le alpha lipoic acid se ka hlahisoa ke ho khopisa litho tsa mucous tsa mala, mala. Matšoao a bosholu: bohloko ba ka mpeng ka ho hlatsa le lets'ollo.

Berlition ka kalafo ea osteochondrosis

Ka mokhoa oa ho phekoloa ka Berlition, bohloko le maikutlo a tukang sebakeng se amehileng sa vertebra lia fokotseha

Boemong ba osteochondrosis e sa foleng, ka nts'etsopele ea khatello ea methapo ea methapo ea methapo ea methapo, ho potoloha ha mali le ho lula sebakeng se anngoeng ke koluoa, lithethefatsi tse ka fokotsang methapo ea mali le ho tloaela trophism ea tishu li bohlokoa.

Lenaneng la lithethefatsi tse nang le phello ea vasodilating, ntle le Trental, Eufillin le Actovegin, Berlition e sebelisoa.

Le har'a li-microcirculation tse ntlafalitsoeng ho lithethefatsi tsa vasodilator, Berlition e ntlafatsa sephetho sa ho hlaphoheloa.

Ka lebaka la sena, ts'ebetso ea ho lokisa pheletso ea methapo e senyehileng le karolo e tloaelehileng ea 'mele ea ts'usumetso ea methapo e ea hlasimoloha.

Phekolo ea Berlition e ka fokotsa haholo liketsahalo tse joalo ka maikutlo a tukang sebakeng se anngoeng ke lesapo la mokokotlo, ho lutla, ho tsitsipana le bohloko.

Ts'ebeliso ea matlapa

Likhohlopo tsa moriana o nooa hoseng ka mpeng e se nang letho. Ka tekanyetso e le 'ngoe, ho nooa tekanyetso ea Berlition ea letsatsi le letsatsi.

Halofo ea hora kamora ho nka senepe, mokuli a ka ja lijo.

Le osteochondrosis, ho fanoa ka litekanyetso tsa letsatsi le letsatsi tsa likarolo tse 600.

Mafung a matla a sebete, litekanyetso tsa letsatsi le letsatsi tsa lithethefatsi li imena habeli, 'me tsamaiso ea methapo kapa ea methapo e tlatselletsoa ka mokhoa o fapaneng.

Ts'ebeliso ea ampoules 300 le 600

Bakuli ba maemong a hlobaetsang a lefu lena ba fuoa 300-600 IU ea lipoic acid (e le 'ngoe kapa tse peli tsa ampole ea Berlition).

Ntle le infusions ea methapo ea kutlo, ente ea methapo ea methapo ea methapo ea methapo ea methapo ea methapo e ka fuoa kalafo ea osteochondrosis.

E le ho qhela mathata a ka bang teng le nts'etsopele ea karabelo ea anaphylactic, lits'ebetso tsa tsamaiso ea lithethefatsi li lokela ho etsoa feela mekhatlong ea bongaka e hlokometsoeng ke basebetsi ba bongaka.

Tekanyo ea joala

Berlition ha e lumellane le joala le lithethefatsi tse nang le joala. Li-Alcohols le li-metabolites tsa tsona li khelosa ketso le kalafo ea alpha-lipoic acid.

Lebitso la lithethefatsi	Theko	Reka
Berlition 300 n30 tabl	ho tloha ho 808 rub.	Ho reka
Berlition Matlapa a 300mg 30pcs	ho tloha ho 793 rub.	Ho reka
Berlition li-ampoules 300ed 12ml 5 li-PC.	ho tloha ho 611 rub.	Ho reka
Litlatsetso tsa Berlition li tsepamisa likarolo tsa 600 25 mg / ml 24 ml n5 amp	ho tloha ho 876 rub.	Ho reka

ho litaba tse kahare ↑

Li-analoggs tsa moriana matlapeng

Lipoic acid. Moetsi: Uralbiopharm, OJSC (Russia). Letlapa le leng le koahetsoeng le na le 12 mg ea 25 mg ea alpha lipoic acid. E bua ka li-metabolic le detoxification agents.

Tiolepta. Mohlahisi: CJSC Canonfarm Production (Russia). E fumaneha ka litekanyetso tse peli: 300 le 600 IU ea motsoako o sebetsang oa alpha-lipoic acid.

Matlapa a bobebe a mosehla ka har'a mekotla ea lithupa ea likotoana tse 10 kapa tse 15.

Oktolipen. Moqapi oa Pharmstandard-UfaVITA (Russia). E fumaneha ka litekanyetso tse peli: Diyuniti tse 300 le tse 600 tsa alpha lipoic acid. E khethoa e le moemeli oa hepatoprotective, hypoglycemic le neuroprotective.

Linepe tsa lithethefatsi:

Espa lipon. Mohlahisi: Tšoenyeho ea meriana Esparma, Jeremane. Matlapa, (200 le 600 PIECES of alpha lipoic acid) a tletse ka lebokoseng la likotoana tse 30. Ho ea ka litaelo, sethethefatsi se bontšoa bakeng sa neuropathies, mafu a sebete le tahi.

Tiogamma. Mohlahisi: Tšoenyeho ea meriana Verwag Pharma (Jeremane). Letlapeng le le leng ho na le 600 PIECES ea alpha lipoic acid.

Thioctacid. Mohlahisi: Tšoenyeho ea meriana Meda Pharma, Jeremane. Matlapa, a kentsoeng ka botlolong ea li-pcs tse 30, ka tekanyetso ea li-unit tse 600, ka motsoako o ka sehloohong oa alpha-lipoic acid.

Analogs of Berlition 300

Lipothioxone
Oktolipen 300,
Tiolepta
Thiolipone.

Pharmacodynamics, pharmacokinetics e nang le litlamorao, litekanyetso le mokhoa oa kopo li tšoana le Berlition 300 IU.

Litšoantšiso tsa moriana, eseng haufi le sebopeho, empa ho latela mochini oa ts'ebetso 'meleng (sehlahisoa se le seng sa pharmacological) li kenyeletsa:

Bifiform
Orfadin,
Gastricumel (pheko ea homeopathic).

Berlition kapa Thioctacid - e leng betere?

Ho Thioctacid le Berlition kamano e lekana. Lithethefatsi ka bobeli li hlahisoa mathateng a meriana ea Jeremane ka botumo bo botle. Ho etsa qeto ea hore na ho na le molemo ofe o ka khonehang feela, ha lithethefatsi tsena ka bobeli li tla sebelisetsoa kalafo.

Ksenia ea lilemo tse 29:Kamora ho nka Tiogamma, ho tsekela le ho fokola haholo ho ile ha hlaha matlapeng. Ke ne ke sa batle ho ja ho hang, lijo li ne li bonahala li se monate. Kamora 'kalafo, ntho e ngoe le e ngoe e ile ea fola, empa ha a ka a ikutloa a ntlafala maemong a bophelo. Mohlomong kamora 'nete ea pele ke ntho e tloaelehileng? Mohlomong, ho utloisisa phello ea lithethefatsi, o hloka ho phekoloa lilemo tse peli ho isa ho tse tharo. Ha ho na letho leo u ka buang ka lona.

Karina ea lilemo tse 34:Hoo e ka bang lilemo tse peli tse fetileng, o ile a tšoaroa ke Berlition. Ke fuoe moriana sepetlele. Kamora ho putlama, hlooho ea ka e ne e hlohlona, ho bile le bofokoli bo matla. Kamora, ha Berlition e ne e laetsoe kalafo e 'ngoe ho li-capsules, ho ne ho se na maikutlo a joalo a sa thabiseng.

Michael ea lilemo tse 36:Ha ke tsebe, Berlition e nthusitse, kapa litokisetso tsohle hammoho, empa sebete se ile sa kokobela kamora lefu la Botkin, 'me ke ikutloa hantle.

Ivan ea lilemo tse 27:Kamora hore ngaka e ntlatsetse kalafo le Berlition, bohloko ba ka ba mokokotlo o karolong e neng e se e le haufi le ho emisoa bo ile ba emisa ho nkhathatsa hangata. Kamora moriana, ke ile ka ba le mokhoa o sa thabiseng oa ho hlatsa mahlo, ho akheha le ho thothomela.

Melemo ea pharmacological

Mofumahali Sesebelisoa sa mantlha sa motsoako ke antioxidant ea tlhaho e kopanyang li-radicals tsa mahala. Acid e hlahisoa ke 'mele ka lebaka la litla-morao tsa oxidative ho li-acid tsa α-keto.

Ela hloko! Litlhahlobo tsa lingaka li bonts'a hore moriana o na le phello e molemo ho theoleng tsoekere ea mali, ho eketsa maemo a glycogen a sebete le ho hlola khanyetso ea insulin.

Ka thepa ea bona ea biochemical, matlapa a Berlition 300 le 600 a haufi le livithamini tsa B.

Nka karolo ho tloaelehileng ea carbohydrate le lipid metabolism.
Ntlafatsa ts'ebetso ea sebete, hlohlelletsa metabolism ea cholesterol.
Ba na le hypoglycemic, hepatoprotective, hypocholesterolemic, hypolipidemic effect.

Ts'ebeliso ea Berlition 300 le 600 ho infusions bakeng sa ente ea intravenous e ka fokotsa botebo ba karabelo e fosahetseng.

Mofumahali Matlapa a Berlition 300 le 600, kapa, lintho tsa ona tse sebetsang, a khona ho "feta pele" ka har'a sebete. Thioctic acid le likarolo tsa eona li batla li lekantsoe ka botlalo (80-90%) ke liphio.

Tharollo ea ente Berlition. Nako ea ho fihlela khatello e phahameng 'meleng ka tsamaiso ea methapo e 10 ke metsotso e 10-11. Sebaka se tlas'a curveutical curve (nako ea mahloriso) ke 5 μg h / ml. Khatello e kholo ke 25-38 mcg / ml.

Matlapa a Berlition bakeng sa tšebeliso ea molomo a kenella ka potlako 'me a kenella ka botlalo mokhoeng oa ho silila. Ha e nkoa ka lijo, adsorption ea fokotseha. Khatello e phahameng ea lithethefatsi e fihlella ka mor'a metsotso e 40-60. Bioavailability ke 30%.

Bophelo ba halofo ke metsotso e 20-50. Tlhahiso ea plasma ka botlalo ke 10-15 ml / min.

Likarolo tse ling tsa lithethefatsi

Litlhahlobo tsa lingaka le bakuli ka Berlition li ntle haholo, empa joalo ka lithethefatsi tse ling, e na le litšobotsi tsa eona. Nakong ea kalafo, bakuli ba lokela ho hana ho itlopa joala.

Litsebi tsa lefu la tsoekere li hloka ho hlahlojoa khafetsa maemong a tsoekere ea plasma. Sena ke sa bohlokoa haholo qalong ea kalafo.Ka linako tse ling ho ka hlokahala ho fokotsa tekanyetso ea lithethefatsi tsa insulin kapa hypoglycemic tse nkuoang ke bakuli ka hare. Kahoo, kotsi ea hypoglycemia e thibetsoe.

Tharollo ea ente ea Berlition 300 kapa 600 e lokela ho sireletsoa mahlaseling a UV. Sena se etsoa ka ho phuthela botlolo ka foil ea aluminium. Tharollo e sirelelitsoeng ka tsela ena e ka bolokoa lihora tse 7.

Litlamorao

Hangata, ha li etsahale, empa maemong a sa tloaelehang, ka mor'a ho thella ka tharollo, ho tsitsipana, hemorrhages e nyane ho li-membrane tsa mucous le letlalo, hemorrhagic rash, thrombocytosis lia etsahala. Ka tsamaiso e potlakileng haholo, ho na le monyetla oa khatello ea maikutlo le ho hema ka thata.

Litlhahlobo tse tsoang ho bakuli le lingaka li re matšoao ana kaofela a tsamaea ntle le ts'ebetso.

Ho na le karabelo ea lehae e hlahang sebakeng sa ente. Sena e kanna ea eba urticaria kapa ponahatso e 'ngoe ea ho kula, ho fihlela mokhatlong oa anaphylactic. Nts'etsopele ea hypoglycemia, e kanna ea hlahisoa ke ntlafatso ea ho monya tsoekere, ha e qheleloe ka thoko.

Matlapa a Berlition hangata a mamelloa ntle le litlamorao tse mpe. Empa ka linako tse ling mathata a latelang a ka etsahala:

ho hloleha ho phefumoloha
pelo e bohloko
ho nyekeloa
ho hlatsa
hypoglycemia nakong ea kemolo,
urticaria.

Ho sebelisana le meriana e meng

In vitro Berlition e kopana le metsoako ea tšepe. Mohlala, cisplatin e ka nahanoa. Ka hona, ho sebelisoa ka nako e le 'ngoe le cisplatin ho fokotsa phello ea eona.

Empa phello ea lithethefatsi tsa hypoglycemic tsa molomo le insulin, Berlition 300 kapa 600, ho fapana le hoo, ea matlafala. Ethanol, e fumanoang lino tse tahang, e fokotsa ts'ebetso ea kalafo (litekolo tsa bala).

Motsoako o sebetsang oa Berlition, ha o sebetsana le tsoekere, o etsa metsoako e ke keng ea qhibiliha. Ka mor'a moo, tharollo ea thioctic acid e ke ke ea kopana le ho kenella ka dextrose, Ringer le tharollo tse ling tse tšoanang.

Haeba Berlition 300, matlapa a 600 a ne a nkuoe hoseng, o ka sebelisa lihlahisoa tsa lebese, magnesium le litokisetso tsa tšepe feela ka mor'a lijo tsa motšeare kapa ka shoalane. Mabapi le lihlahisoa tsa lebese, sena se bakoa ke taba ea hore li na le calcium e ngata.

Ho na le litlolo tse teng

Nako ea kemaro le kanyeso. Le ha litlamorao tse mpe tsa moriana li sa netefatsoa, kaha ha ho na litlhahlobo le lithuto tsa Morero o joalo.
Kutloisiso e phahameng ho likarolo tsa Berlition.
Moriana ha o ngoletsoe bana (ha ho na litlhahlobo mabapi le polokeho le katleho).

Ho boloka, phomolo, ho paka

Setlhare ke sa lethathamo la B. E lokela ho bolokwa ka mocheso o sa feteng 25 ° C, sebakeng se lefifi se sa fumaneheng ho bana.

Nako ea ts'ebeliso e latela mofuta oa tokollo:

tharollo ea ente - lilemo tse 3,
lipilisi - lilemo tse 2.

Berlition e lokolloa feela ka lengolo la ngaka. Tharollo ea ente e fumaneha ka ampoules e lefifi ea 25 mg / ml. Mabokose a likarete tsa (likarete) a na le li-ampoules tse 5. Litaelo tsa tšebeliso ke tsena.

Matlapa a Berlition a koahetsoe 'me a pakiloe ka likotoana tse 10 ka marang-rang a entsoe ka thepa e tsoakiloeng ea PVC kapa foil ea aluminium. Phutheloana ea karete e na le lithupa tse 3 tse joalo le litaelo tsa ho li sebelisa.

Litaelo tsa ho sebelisoa ha Berlition 300: mokhoa le litekanyetso

Tharollo e lokiselitsoeng ho tsoa ho tsepamiso e fanoa butle butle (bonyane metsotso e 30) ka ho kenella ka tekanyetso ea letsatsi le letsatsi ea 300-600 mg (1-2 ampoules) ka nako ea libeke tse 2,2. Ka mor'a moo, mokuli o fetisetsoa ka foromo ea letlhare la lithethefatsi 'me ho sebelisitsoe matlapa a 1-2 ka letsatsi

Nako ea kalafo e akaretsang le tlhoko ea ho pheta-phetoa ha tsona li khethoa ke ngaka ka bonngoe.

Tharollo bakeng sa tsamaiso ea methapo e lokisoa hang-hang pele e sebelisoa. Bakeng sa sena, likateng tsa ampoules tsa 1-2 li hlapolotsoe ka 250 ml ea tharollo ea chloride ea 0,9%. Thioctic acid e tsotella leseli, ka hona tharollo e lokiselitsoeng e lokela ho sireletsoa ho eona, mohlala, u sebelisa foil ea aluminium. Sebakeng se lefifi, mohopolo o qhibilihileng o ka bolokoa nako e sa feteng lihora tse 6.

Matlapa a 300 a Berlition a lokela ho nooa ka molomo nako e le 1 ka letsatsi metsotso e 30 pele ho lijo, a li metse kaofela 'me a noe metsi a mangata.

Batho ba baholo hangata ba fuoa 600 mg (matlapa a 2).

Ngaka e beha qeto ea hore na nako ea kalafo e tla ba telele hakae le hore na ho hlokahala hore lithuto tse phetoang hangata hakae. Setlhare se ka sebelisoa nako e telele.

Berlition 300 ka kakaretso e mamelloa hantle. Tse sa tloaelehang (

Berlition 300 le 600: tlhaloso, litekolo mabapi le ts'ebeliso, li-contraindication

Tšebeliso ea thioctic acid ka mokhoa oa letsoai la ethylenediamine e ka fokotsa botebo ba litlamorao tse ka bang teng.

Ka ho qala / ho hlahisa thioctic acid C_max ho plasma ea mali ka mor'a metsotso e 30 ke hoo e ka bang 20 μg / ml, AUC - hoo e ka bang 5 μg / h / ml. E na le phello ea "mokhoa oa pele" ka sebete. Ho thehoa ha metabolites ho etsahala ka lebaka la oxidation ea lehlakore le thipa. V_d - boholo ba 450 ml / kg. Tlhahiso ea plasma ka kakaretso ke 10-15 ml / min / kg. E epolloa ke liphio (80-90%), haholo ka sebopeho sa metabolites. T_1/2 - e ka ba metsotso e 25

Nahanela tharollo ea infusion botala bo botala, bo pepeneneng.

Bahlomphehi: ethylenediamine - 0,155 mg, metsi d / i - ho fihla ho 24 mg.

24 ml - li-ampoules tsa khalase e lefifi tse nang le bophahamo ba 25 ml (5) le label e tšoeu e bonts'ang mohala oa ho phumula le metsero e meraro (botala-bosehla-botala) - lipallet tsa polasetiki (1) - liphutheloana tsa karete.

Setlhare se etselitsoe tsamaiso ea infusion.

Qalong ea kalafo, Berlition ea lithethefatsi 600 e fanoa kahare ka tekanyetso ea letsatsi le letsatsi ea 600 mg (1 ampoule).

Pele o sebelisoa, litaba tse kahare tsa ampoule e le 'ngoe (24 ml) li kenngoa ka 250 ml ea tharollo ea sodium chloride le ho kenngoa kahare, butle butle, bonyane metsotso e 30. Ka lebaka la bosholu ba ntho e sebetsang, tharollo ea infusion e lokisoa hang-hang pele e sebelisoa. Tharollo e lokiselitsoeng e tlameha ho sireletsoa ho pepesetsoa leseli, mohlala, sebelisa foil ea aluminium.

Nako ea kalafo ka Berlition 600 ke libeke tse 2 ho isa ho tse peli. E le kalafo e latelang ea ho lokisa, thioctic acid e sebelisoa ka mokhoa oa molomo ka tekanyetso ea letsatsi le letsatsi ea 300-600 mg. Nako ea kalafo le tlhoko ea ho pheta-pheta ha eona li khethoa ke ngaka.

Matšoao ho nyekeloa ke pelo, ho hlatsa, hlooho e bohloko.

Maemong a tebileng: ho ferekana kelellong kapa ho ferekana kelellong, ho tsitsinyeha ho akaretsang, ho ferekana ho matla ha tekano ea acid-msingi, lactic acidosis, hypoglycemia (ho fihlela ho nts'etsopele ea komello), masapo a mesifa ea mesifa ea mokokotlo, DIC, hemolysis, khatello ea tšebetso ea moko oa masapo, ho hloleha ha litho tse ngata.

Phekolo: Haeba ho ts'oaroa hoa tahi ea thioctic acid ho belaelloa (mohlala, tsamaiso ea ho feta 80 mg ea thioctic acid ka kilo e le 'ngoe ea boima ba' mele), ho kenella sepetlele ka tšohanyetso le ts'ebeliso ea hang-hang ea mehato e khothalletsoa ho latela melao-kakaretso e amoheloang molemong oa chefo e kotsi. Phekolo ke letšoao. Phekolo ea ho ts'oaroa ka kakaretso, lactic acidosis le litlamorao tse ling tse behang bophelo ba bokhobeng e lokela ho etsoa ho latela melaoana ea tlhokomelo ea sejoale-joale e matla. Ha ho na litlhare tse tobileng. Hemodialysis, hemoperfusion kapa filtration mekhoa ka ho tlosoa ka qobello ea thioctic acid ha e sebetse.

Ka lebaka la hore thioctic acid e khona ho theha li-chelate complexes ka tšepe, tsamaiso e ts'oanang ka litokisetso tsa tšepe e lokela ho qojoa. Tšebeliso e le 'ngoe ea lithethefatsi Berlition 600 e nang le sisplatin e fokotsa katleho ea eona.

Thioctic acid e bopa metsoako e rarahaneng e sa qhibilihang le limolek'hule tsa tsoekere. Lithethefatsi Berlition 600 ha e lumellane le litharollo tsa glucose, fructose le dextrose, tharollo ea Ringer, hammoho le tharollo e arabelang ka ho se lumellane le lihlopha tsa SH-group.

Sethethefatsi Berlition 600 se ntlafatsa phello ea hypoglycemic ea li-insulin le li-hypoglycemic agents bakeng sa tsamaiso ea molomo ka tšebeliso e tšoanang.

Ethanol e fokotsa haholo katleho ea kalafo ea thioctic acid.

Litlamorao tse ka bang teng ha u sebelisa lithethefatsi Berlition 600 li fanoa ka tlase ho tlatsana le maemo: hangata (≥1 / 100, litekolo tse ling tse 4 ke lingaka

Berlition - sethethefatsi se sebetsang hantle haholo kalafong ea osteochondrosis

Alpha lipoic acid, vithamini N, e na le thepa e tšoanang le livithamini tsa B. Alpha lipoic acid e nkoa e le e 'ngoe ea li-antioxidants tsa tlhaho. E khona ho sireletsa mabota a methapo ea mali ho tsoa liphellong tsa li-radicals tsa mahala. Berlition ke e 'ngoe ea lithethefatsi tse tsebahalang haholo tse thehiloeng alpha lipoic acid, e sebelisitsoeng ho osteochondrosis. Setlhare se sebetsa joang, matšoao a sona ke eng, ho na le litšitiso life, 'me se ka nkeloa sebaka ke eng?

Berlition e bua ka lithethefatsi tseo motsoako oa tsona o ka sehloohong e leng alpha lipoic acid.

Ho pharmacology le bongaka, komporo ena e boetse e tsejoa e le lipoic kapa thioctic acid.

Alfa-lipoic acid ka sebopeho sa eona sa lik'hemik'hale le thepa ea eona e tšoana le livithamini, e qhibiliha hantle metsing le mafura.

Phello e ka sehloohong ea alpha lipoic acid:

e kenya letsoho tlhahiso e hlokahalang ea li-enzyme 'meleng,
e potlakisa ts'ebetso ea metabolic,
e khothaletsa ho amoheloa le ho sebetsa hantle ha livithamini le li-antioxidants,
e sebetsa le ho tlosa lisebelisoa tsa mahala:
e sireletsa tlhaho ea limolek'hule tsa DNA,
phello e molemo lits'ebetsong tsa trophic, ho ntlafatsa metabolism ea biochemical intercellular metabolism,
normalizing mosebetsi oa methapo ea methapo ea kutlo,
e laola lik'habohaedreite, mafura a lekanang.

Alpha lipoic acid, eo hape e bitsoang oxidant ea bokahohleng, e hlokahala bakeng sa likarolo tsohle tsa 'mele tsa mmele. Empa lisele tsa boko, methapo ea kutlo le ea sebete ho alpha lipoic acid haholo hloka, 'me o na le bothata ba ho hloka acid ena.

Ka hona, karolo ea tšebeliso ea alpha-lipoic acid e pharaletse haholo:

Tšenyo ea methapo ea kutlo,
lefu la tsoekere le angiopathy,
glaucoma
lefu la sebete
kalafo ea litlamorao tsa chefo ea lik'hemik'hale,
e le mokhoa oa ho phekola tšoaetso ea HIV, lefu la tsoekere.

Ha ho nkoa ka molomo, moemeli ea nang le alpha lipoic acid e kenella ka botlalo ka mpeng e nyane.

Alpha-lipoic acid e le karolo e sebetsang e hlahisoa ho Berlition ea lithethefatsi, e entsoeng ke k'hamphani ea litlama Chemie (Jeremane).

Setlhare ke sa sehlopha sa hepatoprotectors, li-agents bakeng sa kalafo le ho hlokomela mesebetsi ea sebete.

Ho ea ka mofuta oa tokollo, setlhare se hlahisoa:

Kameho e tebileng bakeng sa ho hlophisoa ha tharollo ea ente - ampoules 12 mg, e nang le alpha-lipoic acid e nang le 300 mg (UNITS). E kentsoe li-ampoules tse 5.10.15 ka lebokoseng la karete.
Ka har'a mohopolo bakeng sa ho hlophisoa ha tharollo ea ente, ho na le li-ampoule tse 24 mg tse nang le lethathamo la motsoako o ka sehloohong oa alpha lipoic acid ea 600 mg (UNITS). E kentsoe li-ampoule tse 5 kapa tse 10 ka lebokoseng la karete.
Ka li-capsules tse bonolo tsa gelatin bakeng sa tsamaiso ea molomo - 300 mg ea alpha-lipoic acid. E pakiloe ka foromo ea li-contour mesh le lebokose la karete.

Setsi se amanang le lifoto:

Lithethefatsi li fanoa ka mokhoa oa kalafo ea adjunctive e le ho potlakisa metabolism ea matla, ho ntlafatsa lisele tsa trophic, ho etsa hore mmele o lekanye mmele le ho leka-lekana ha lipid 'meleng.

Berlition (alpha lipoic acid) e bonts'itsoeng:

liphetoho tsa atherosselotic likepeng tsa coronary,
phokolo ea mali
hypotension
ka methapo ea lesapo la mokokotlo le lefutso,
Ho taoa ho matla le ho sa foleng hoa lisosa tse sa tšoaneng (ho chefo ka letsoai la litšepe tse boima, chefo, joala),
polyneuropathies ea mabelo a holimo le a tlase (ho ruruha, chefo, allergic, ho sithabetsa, lefu la tsoekere, autonomic),
Ho senyeha hoa tlhaho ho lisele tsa bokong le mokokotlong,
endocrine pathologies e amanang le mathata a metabolic.

Berlition ea lithethefatsi e na le likhohlano.

Ka tlhokomeliso, tlasa taolo ea glycemic, setlama se nang le acid sa acid se ngoletsoe bakuli ba nang le lefu la tsoekere leha e le lefe.

Berlition ha e fuoe kalafo kalafong ea bana, basali nakong ea kemolo, ho beleha.

Meriana e thehiloeng ka alpha-acid e nang le acid e thibetsoe 'me ha e sebelisoe ho batho ba nang le bothata ba ho se mamellane ha fructose, khaello ea lactose, galactosemia.

Berlition e lokela ho sebelisoa feela kamora ho khothaletsoa kapa ho khethoa ha ngaka.

Berlition ka kakaretso e mamelloa hantle. ke bakuli. Litla-morao li ka ba maemong a sa tloaelehang, a feteletseng.

Ke matšoao afe a ka bonts'ang litla-morao tsa lithethefatsi tse thehiloeng ho alpha lipoic acid:

dyspepsia: ho nyekeloa ke pelo ka ho hlatsa, lets'ollo, ho qhekella, ho opeloa ke pelo ho epigastrium,
tatso e fetotsoeng
hlooho e bohloko, ho tsekela, ho ikutloa eka o boima hloohong, ho hlohlona, ho sitisoa hoa pono ka sebopeho sa lintsintsi tse benyang, ho iketla ha lintho,
liponahatso tse kholisang, ho thothomela hoa liphello,
mafu a pelo a mofuta oa hyperemia ea letlalo, maikutlo a ho ba le mathata a mangata, tachycardia,
allergic lipontšo tsa vv ka mokhoa oa rashes, ho hlohlona ha letlalo le urticaria.

Nako ea kalafo e nka likhoeli tse ka bang peli.

Tekanyetso le mokhoa oa tsamaiso ea litlhare Berlition o khethoa ke ngaka ka bonngoe.

Ka tloaelo, Berlition e fanoa ka molomo ka tekanyetso ea li-unit tse 600 hang bakeng sa kalafo ea polynyropathies hang pele ho lijo tsa hoseng.

Bakeng sa mafu a matla, joalo ka kalafo ea adjunct, ts'ebeliso e kopaneng ea lithethefatsi Berlition e bonts'oa: ente ea li-capsules.

Tharollo ea Berlition e fanoa ka methapo (likarolo tse 300 kapa tse 600) bakeng sa beke e le 'ngoe ho isa ho tse peli hoseng.

Sebopeho sa moriana bakeng sa ente ke ntho e kenelletseng, eo pele ho tsamaiso e kenngoeng ka letsoai la 'mele ka bongata ba 250 ml (vial).

Kamora ho fokotseha ha lingaka, ngaka e beha ts'ebetso e eketsehileng ea lithethefatsi ka alpha-lipoic acid (ka molomo, likhabapo).

Likokoana-hloko tsa Berlition 300 U li ka fanoa ka intramuscularly bakeng sa libeke tse 2-4. Maemong ana, mohopolo oa lithethefatsi o hlapolotsoe ho 2 ml ea saline ea mmele.

Tsela ea teraria ka Berlition hangata e nka likhoeli tse peli. Ho ea ka bopaki, khoso ea bobeli ea kalafo ka moriana o thehiloeng ho alpha-lipoic acid e fanoe kamora likhoeli tse tšeletseng.

Ka mokhoa oa ho phekoloa ka Berlition, bohloko le maikutlo a tukang sebakeng se amehileng sa vertebra lia fokotseha

Lenaneng la lithethefatsi tse nang le phello ea vasodilating, ntle le Trental, Eufillin le Actovegin, Berlition e sebelisoa.

Le har'a li-microcirculation tse ntlafalitsoeng ho lithethefatsi tsa vasodilator, Berlition e ntlafatsa sephetho sa ho hlaphoheloa.

Ka lebaka la sena, ts'ebetso ea ho lokisa pheletso ea methapo e senyehileng le karolo e tloaelehileng ea 'mele ea ts'usumetso ea methapo e ea hlasimoloha.

Phekolo ea Berlition e ka fokotsa haholo liketsahalo tse joalo ka maikutlo a tukang sebakeng se anngoeng ke lesapo la mokokotlo, ho lutla, ho tsitsipana le bohloko.

Ke setsebi sa methapo feela se fanang ka kalafo le Berlition bakeng sa osteochondrosis. Tekanyetso, mokhoa oa kalafo le mokhoa oa ts'ebetso ea lithethefatsi o tla khethoa ho latela mohato oa osteochondrosis (o hlobaetsang kapa o sa foleng), boteng ba matšoao, li-pathologies tsa khokahano le tlhaiso-leseling ea molaotheo.

Likhohlopo tsa moriana o nooa hoseng ka mpeng e se nang letho. Ka tekanyetso e le 'ngoe, ho nooa tekanyetso ea Berlition ea letsatsi le letsatsi.

Halofo ea hora kamora ho nka senepe, mokuli a ka ja lijo.

Le osteochondrosis, ho fanoa ka litekanyetso tsa letsatsi le letsatsi tsa likarolo tse 600.

Mafung a matla a sebete, litekanyetso tsa letsatsi le letsatsi tsa lithethefatsi li imena habeli, 'me tsamaiso ea methapo kapa ea methapo e tlatselletsoa ka mokhoa o fapaneng.

Bakuli ba maemong a hlobaetsang a lefu lena ba fuoa 300-600 IU ea lipoic acid (e le 'ngoe kapa tse peli tsa ampole ea Berlition).

Ntle le infusions ea methapo ea kutlo, ente ea methapo ea methapo ea methapo ea methapo ea methapo ea methapo e ka fuoa kalafo ea osteochondrosis.

Bakeng sa ho kenyelletsa litlamorao tse mpe tsa kalafo le Berlition, o lokela ho latela litaelo ka mokhoa o hlakileng, o se ke oa fana ka litlhare ka seqo, o se ke oa feta tekanyo e khothalelitsoeng.

Lithethefatsi tse thehiloeng ho alpha lipoic acid li thibetsoe bakeng sa kalafo ea basali nakong ea kemolo, ho lactation.

Berlition ha e lumellane le joala le lithethefatsi tse nang le joala. Li-Alcohols le li-metabolites tsa tsona li khelosa ketso le kalafo ea alpha-lipoic acid.

Matlapa a koahetsoeng ka filimi pota, biconvex, mmala o mosehla, o nang le notch ka lehlakoreng le leng, pono e tšekaletseng: bokaholimo bo sa lekanang ba 'mala oa mosehla o bobebe.

Baeti: lactose monohydrate - 60 mg, croscarmellose sodium - 24 mg, colloidal silicon diode - 18 mg, microcrystalline cellulose - 165 mg, povidone (K-30) - 21 mg, magnesium stearate - 12 mg.

Li-pcs tse 10 - lithutsoana (3) - lipakete tsa karete.
Li-pcs tse 10 - lithutsoana (6) - lipakete tsa karete.
Li-pcs tse 10 - marang-rang (10) - lipakete tsa karete.

Thioctic (α-lipoic) asiti, e leng endo native antioxidant (e kopanyang li-radicals tsa mahala), e thehoa 'meleng nakong ea oxidative decarboxylation ea acid ea α-keto. Ha e le coenzyme ea mitochondrial multenzyme complexes, e nka karolo ho oxidative carboxylation ea pyruvic acid le α-keto acid.

E na le hepatoprotective, hypolipidemic, hypocholesterolemic, hypoglycemic effect.

Ho rekisa le ho tsamaisa

V_d - boholo ba 450 ml / kg.

Metabolism le excretion

E na le phello ea "mokhoa oa pele" ka sebete. Ho thehoa ha metabolites ho etsahala ka lebaka la oxidation ea lehlakore le thipa.

Thioctic acid le metabolites ea eona li kentsoe moroto (80-90%). T_1/2 - Metsotso e 20-50 Tlhahiso ea plasma ka botlalo ke 10-15 ml / min.

- lilemo tsa bana (katleho le polokeho ha li so theoe),

- boimana (ha ho na boiphihlelo bo lekaneng ka tšebeliso ea lithethefatsi),

- ho anyesa (ha ho na boiphihlelo bo lekaneng ka tšebeliso ea lithethefatsi),

- Hypersensitivity ho likarolo tsa moriana.

Ka hare, 600 mg (matlapa a 2) a behiloe nako e le 1 / letsatsi. Matlapa a nooa ka mpeng e se nang letho, metsotso e ka bang 30 pele ho lijo tsa pele, ntle le ho hlafuna le ho noa metsi a mangata. Nako ea kalafo e khethoa ke ngaka ka bonngoe.

Ho tsoa ts'ebetsong ea tšilo ea lijo: ho khonahala (kamora tsamaiso ea molomo) – dyspepsia, ho kenyelletsa ho nyekeloa ke pelo, ho hlatsa, ho opeloa ke pelo.

Ka lehlakoreng la metabolism: hypoglycemia (ka lebaka la ntlafatso ea tsoekere e ntlafalitsoeng).

Litla-morao: maemong a mang - urticaria.

Phekolo: matšoao. Ha ho na litlhare tse tobileng.

In vitro, thioctic (α-lipoic) acid e sebelisana le li-complexes tsa ionic tsa tšepe (mohlala, cisplatin). Ka hona, ka tsamaiso e le 'ngoe, ho fokotseha ha phello ea sisplatin ho ka etsahala.

Kamora ho nka Berlition 300 hoseng, ho kgothaletswa ho sebelisa lihlahisoa tsa tšepe, magnesium le lebese (ka lebaka la khalori ea bona ea calcium) kamora lijo tsa motšeare kapa ka shoalane.

Ka tšebeliso e tšoanang ea ethanol le metabolites ea eona li ka fokotsa ts'ebetso ea kalafo ea thioctic (α-lipoic) acid.

Ka tšebeliso e tšoanang ea Berlition 300 e ntlafatsa phello ea hypoglycemic ea li-insulin le li-agent tsa hypoglycemic tsa molomo.

Bakuli ba nkang Berlition 300 ba lokela ho hana ho noa joala.

Setlhare ke ngaka.

Lenane B. Setlhare se lokela ho bolokoa se sa fihlelloe ke bana ka mocheso o sa feteng 25 ° C. Bophelo ba Shelf ke lilemo tse 2.

">," Content_to_web ":" Kajeno ke nkile sethethefatsi sena ka har'a lipilisi mme ke ne ke utloile bohloko haholo. E bitsa chelete e ka bang $ 30 (Berlition 600 mg), mme joale e tla tlameha ho lahloa: e na le "supplement-dye E123 (Amaranth)" e kotsi haholo (carcinogen, e netefalitseng ho eketsa monyetla oa makhopho a mofets'e, a bakang mathata a tlhaho le tsoelo-pele ea malfform pelo ea fetal ho basali ba baimana) mme e thibetsoe hore e sebelisoe Russia le Ukraine (potso ke hore, ba rekisa seno joang ho li-pharmacy?). Batla ka har'a enjine ea ho batla tlhaiso-leseling ho tlatsetso ea E123 - u tla fumana lintho tse ngata tse khahlisang. "," Made_at ":," href ":" / comments / permalink / 16836/1026 / "," e ngotsoe ": leshano," id ": 1026>," e bōpiloe_at ":," Href ":" / comments / permalink / 16836/1211 / ">,

">," Content_to_web ":" Kajeno ke nkile sethethefatsi sena ka har'a lipilisi mme ke ne ke utloile bohloko haholo. E bitsa chelete e ka bang $ 30 (Berlition 600 mg), 'me joale e tla tlameha ho lahloa: e na le "supplement-dye E123 (Amaranth)" e kotsi haholo (carcinogen, e netefalitseng ho eketsa menyetla ea makhopho a mofets'e, e bakang mathata a tlhaho le tsoelo-pele ea malfform pelo ea fetal ho basali ba baimana) mme e thibetsoe hore e sebelisoe Russia le Ukraine (potso ke hore, ba rekisa seno joang ho li-pharmacy?). Sheba ka har'a enjene ea ho batla tlhaiso-leseling ho tlatsetso ea E123 - u tla fumana lintho tse ngata tse khahlisang. "," Parent_reply ": null," made_at ":," href ":" / comments / permalink / 16836/1026 / ">," mosebelisi ": null >>> ”>

Gardner David, Schobeck Dolores Basic and Clinical Endocrinology. Buka ea 2, Beanom - M., 2011 .-- 696 c.
Pheko ea mafu a endocrine. Meqolong e 'meli. Buka ea 2, Meridians - M., 2015 .-- 752 leq.
Gurvich, M.M. Lijo tsa lefu la tsoekere / M.M. Gurvich. - M .: GEOTAR-Media, 2006. - 915 leq.

E re ke itsebise. Lebitso la ka ke Elena. Ke qetile lilemo tse fetang 10 ke sebetsa ke le setsebi sa endocrinologist. Ke lumela hore hajoale ke setsebi lebaleng la ka mme ke batla ho thusa baeti bohle ba sebakeng sena ho rarolla mesebetsi e rarahaneng eseng joalo. Lisebelisoa tsohle tsa sebaka sena sa marang-rang li bokelloa ebe li sebetsoa ka hloko e le hore li fetise litaba tsohle tse hlokahalang ka hohle kamoo ho ka khonehang. Pele o sebelisa se hlalosoang webosaeteng, ho hlokahala tumellano ea ho buisana le litsebi kamehla.