Taolo ea lefu la tsoekere

Diabetesalong ke lithethefatsi tse hlophiloeng tse sebelisoang e le karolo ea mofuta oa kalafo ea monotherapy kapa mofuta oa kalafo ea lefu la tsoekere la mofuta oa 2. Matlapa a Diabetesalong a laetsoe ho sa na le phello e kholo ea tokiso ea lijo le ts'ebetso ea 'mele ea mokuli, e tsamaellanang le lilemo tsa hae le litšobotsi tsa' mele.

Phekolo le sethethefatsi e lokela ho kopanngoa le phepo ea kalafo (tafoleng ea 9) - sena sea hlokahala ho thibela tlhaselo ea hypoglycemic le ho eketsa katleho ea kalafo.

Karolo e khethollang ea lithethefatsi ke tokollo ea nako e telele ea ntho e sebetsang, e lumellang ho fokotsa tekanyetso ea letsatsi le letsatsi ea lithethefatsi le ho etsa bonnete ba hore tsoekere e tšoanang le ea tsoekere e sehlopheng sa mali a potoloha.

Kopo

"Diabetalong" e bua ka sehlopha sa lithethefatsi tse nang le phello ea hypoglycemic, e sebelisoang e le kalafo e ka sehloohong bakeng sa lefu la tsoekere le sa ts'epeng le "insulin". Ntho e sebetsang ea matlapa ke gliclazide.

Sena ke setlhare se nang le ts'ebetso e phahameng ea ho khetha, hammoho le bioavailability le eketseha ea ho hanyetsa libaka tse fapaneng tsa tlhaho.

Phello ea kalafo ea lithethefatsi e bakoa ke thepa ea gliclazide, eo har'a eona:

• secretion e eketsehileng ea insulin ea bona, e fokotsang litekanyetso tsa hormone e kentsoeng maling,
• ts'usumetso ea tšebetso ea lisele tsa beta (lisele tse etsang lithane tsa pancreatic le ho netefatsa thepa ea eona ea endocrine),
• normalization ea carbohydrate metabolism (haholo-holo ho bakuli ba nang le botenya ba mofuta oa lefu la tsoekere 2, 3 kapa 4 degrees),
• inhibition ea platelet aggregation (fusion) le thibelo ea thrombocytopenia, thromboembolism le thrombosis.

Ho pakoa hore Diabetesalong e na le ts'ebetso ea lithibela-mafu ebile e fokotsa haholo menyetla ea ho ba le mathata a bolaeang a tsoang pelong, methapong ea mali, litho tsa tšilo ea lijo le bokong.

Ntho e sebetsang ea lithethefatsi e na le tokollo ea nako e telele, 'me khatello ea eona e phahameng e fihlella ka nako ea lihora tse 4-6.

Tšusumetso ea lithethefatsi e bolokiloe lihora tse ling ho isa ho tse 12, 'me halofo ea bophelo e tsoa ho lihora tse 6 ho isa ho tse 12 (ho latela ts'ebetso ea sisteme ea renal).

Letšoao bakeng sa ho fanoa ke moriana oa lithethefatsi ke mofuta oa "lefu la tsoekere" la 2 - mofuta o ikemetseng moo mokuli a bang le hyperglycemia (keketseho e tsitsitseng ea tsoekere ea mali) le kutloisiso ea "tisulin" ea "insulin" e senyehile.

Fomu ea tokollo

"Diabetesalong" e fumaneha ka foromo e le 'ngoe ea litekanyetso - matlapa a lokolotsoeng kapa a lokisitsoeng. Fektheri ea meriana e hlahisa litekanyetso tse peli tsa moriana:

• 30 mg (pakete ea likotoana tse 30) - e khothalelitsoe mohato oa pele oa kalafo.
• 60 mg (pakete ea likotoana tse 60).

Moqapi o sebelisa li-additives tse tloaelehileng e le likarolo tse thusang, ka mohlala, calcium stearate, silicon dioxide le talc.

Ho se ts'oarelle ha moriana ho ka bakoa ke lactose (ka sebopeho sa monohydrate) - limolek'hule tsa tsoekere ea lebese le limolek'hule tsa metsi.

Bakuli ba nang le bofokoli ba tlhaho ea lactase ba ka ba le mathata a dyspeptic, ka hona, ka lefu lena la methapo, li-analogues kapa li-substitute tse nang le thepa e tšoanang e se nang tsoekere ea lebese li lokela ho khethoa.

Matlapa a soeufetse ebile a sephara ka sebōpeho sa silinda.

Maemong a mang, moriana o ka ba le mokokotlo oa mokokotlo - ketsahalo ena e hlalosoa ke ho aroloa hoa tekano ea talcum mme ha e ame likarolo tsa meriana.

Litaelo tsa ho sebelisoa

Litaelo tsa ho sebelisoa "Diabetalong" li khothaletsa ho nwa moriana makhetlo a 1 ho isa ho a mabeli ka letsatsi (ho latela tekanyetso e boletsoeng).

Haeba litekanyetso tsa letsatsi le letsatsi tsa lithethefatsi ke matlapa a 1-2, li lokela ho nooa ka nako e le ngoe hoseng.

Leha taba ea hore semolao se lumella ho nka litafole lipakeng tsa lijo, katleho ea kalafo e tla ba holimo haeba u nka "Diabetesalong" metsotso e 10 - 20 pele u ja.

Haeba mokuli a lebala ho nka pilisi, ho hlokahala hore a qale hape kalafong ea kopo e latelang e fanoeng ke regimen e sebelisitsoeng ea tšebeliso le litekanyetso.

Se ke oa eketsa lethal (ka mohlala, u ke ke ua nka lipilisi tsa hoseng mantsiboea), kaha sena se ka lebisa ho hlaselong e matla ea hypoglycemia le nts'etsopele ea komello, haholo bathong ba fetang 65 le bakuli ba kotsing.

Contraindication

Pele u nka meriana efe kapa efe ea hypoglycemic, o lokela ho etela ngaka, 'me khahlanong le semelo sa kalafo, hoa hlokahala ho laola boemo ba tsoekere le ts'ebetso ea ts'ebetso ea renal.

Ho thibetsoe ho sebelisa lithethefatsi sehlopheng sena bakeng sa lefu la tsoekere la mofuta oa 1, kaha sena se ka lebisa ho bokellana ho matla ha insulin liseleng.

Lihlahisoa tse thehiloeng ho Glyclazide li hanyetsanoa ho basali ba baimana le bo-'mè ba anyesang, hobane li ka baka tšenyo e matla ea endocrine le litla-morao tsa pelo ho lesea le lecha.

Lintho tse ling tse khahlano le ho fana ka taelo ea lefu la tsoekere li kenyeletsa:

• methapo e matla ea liphio le sebete, e lebisang ho se sebetseng hantle hoa setho,
• maemo a hlobaetsang a tsamaeang le tlolo ea metabolism ea carbohydrate,
• karabelo e tsitsitseng ea ho hloka mamello kapa hypersensitivity ho lintho tse tsoang sehlopheng sa sulfonylurea derivatives kapa sulfonamides,
• lefu la tsoekere le maemo a pele a lona,
• khaello ea li-enzyme tse felisang tsoekere ea lebese (ka lebaka la ho ba teng ha lactose sebopeho).

Diabetesalong e etselitsoe feela kalafo ea bakuli ba baholo.

Bakeng sa batho ba ka holimo ho lilemo tse 65, moriana o ka laeloa ho latela tlhahlobo ea khafetsa ea methapo ea mali le moroto, hammoho le tumello ea creatinine. Ha u fana ka taelo, litekanyetso tsa lithethefatsi tse sebelisitsoeng le tsona li lokela ho nahaneloa. Ho thibetsoe ho nka gliclazide le lithethefatsi tsa antifungal systemic tse thehiloeng ho miconazole, hammoho le Danazol le Phenylbutazone.

Hoa hlokahala ho qala kalafo ka tekanyo e fokolang ea 30 mg (matlapa a lokolotsoeng a lokisitsoeng). Ka tekanyetso e ts'oanang, ho khothalletsoa hore batho ba kotsing ea ho ntlafatsa maemo a hypoglycemic ba nkoe. Lintho tse ka behang motho kotsing ke tsena:

• khaello ea phepo e nepahetseng ka liminerale tse sa lekaneng le livithamini le lijo tse ngata tse nang le lik'habohaedreite le tsoekere.
• botsofe (ho feta 65)
• ho ba sieo nalaneng ea lefu la kalafo ka ts'ebeliso ea lithethefatsi tse fokotsang tsoekere ea mali,
• likhathatso mabapi le ts'ebetso ea litšoelesa tsa adrenal le gland ea pituitary,
• tlhahiso e sa lekanang ea li-hormone tsa qoqotho ea tšoelesa ea qoqotho.
• carotid arteriosulinosis,
• lefu le matla la pelo (ho kenyelletsa le lefu la pelo le methapo ea 3 le 4).

Moriana ka tekanyetso ea 30 mg e nooa hang ka letsatsi hoseng kapa nakong ea lijo tsa hoseng.

Bakeng sa mekhahlelo e meng ea bakuli, litekanyetso li baloa ka bonngoe li nahanela ho teba ha methapo ea methapo, lilemo tsa mokuli, tsoekere ea mali le matšoao a mang a liteko tsa laboratori tsa moroto le mali.

Tekanyetso ea letsatsi le letsatsi ea lithethefatsi ha ea lokela ho feta 120 mg (matlapa a 2 a 60 mg kapa matlapa a 4 a 30 mg).

Litlamorao

Litla-morao tse amanang le lefu la tsoekere ke hlooho e bohloko, tatso e haelloang kelellong, hemolytic anemia, le ho hlaseloa ke lintho tse kulang ka mokhoa oa lekhopho la letlalo. Hangata, ho na le litlaleho tsa mathata a mang, a kenyelletsang:

• ho tsekela
• concelive syndrome
• ho thothomela mmeleng
• tšenyo ea maikutlo e senyehileng,
• ho hema ka thata le ho koenya ho koenya,
• ho fifala ha letlalo le mucous ea lera sclera (hepatitis ea mofuta oa cholestatic),
• ho fokotseha hoa pono,
• keketseho ea khatello ea mali.

Maemong a mang, ho sebelisa lithethefatsi "Diabetalong" ho ka baka likotsi tse matla sebeteng, ho sokela bophelo ba mokuli. Moriana o ka boela oa ama hampe ts'ebetso ea hematopoiesis ea moko oa masapo, ka hona, e lokela ho nkuoa tlasa taolo e tiileng ea setsebi, e kopantsoe le lijo tsa kalafo le ts'ebetso e lekaneng ea 'mele.

Theko ea "Diabetalong" e nkuoa e le theko e tlase bakeng sa mekhahlelo eohle ea bakuli, hobane setlhare ka litšenyehelo se bolela karolo e tlase ea theko. Theko e tloaelehileng ea pakete ea litafole tse 60 ke li-ruble tse 120.

Litlhoko tsa lithethefatsi li ka hlokoa haeba ho e-na le karabelo kapa ho hloka mamello ho eng kapa eng ea likarolo tsa moriana. Ho laola boemo ba tsoekere, ngaka e ka fana ka litlatsetso ho tsoa sehlopheng sa tse tsoang ho sulfonylurea kapa lithethefatsi tse ling tsa hypoglycemic tse nang le phello e tšoanang ea kalafo.

• "Diabeteson" (li-ruble tse 290-320). Analogue ea moralo oa "Diabetalong" ka ntho e le 'ngoe e sebetsang. Setlhare se nkoa se sebetsa haholoanyane ka lebaka la ho qaleha ka potlako ha moriana oa kalafo - boholo bo phahameng ba gliclazide bo fihlella ka plasma ea mali nakong ea lihora tse 2-5.
• "Gliclazide" (li-ruble tse 100-120). Ho hlophisoa ha hypoglycemic ka mokhoa oa phofo, analogue ea Diabetesalong.
• "Bolelele ba Glucophage" (li-ruble tse 170-210). Moriana o nkileng nako e telele o kenyeletsa metformin. E ka sebelisoa e le sethethefatsi se ka sehloohong mme e kopantsoe le insulin le lithethefatsi tse ling ho fokotsa tsoekere.

Ha ho khonehe ho hlakola lithethefatsi tse nang le thepa ea hypoglycemic ka boeona, hobane li hloka ho tlosoa butle-butle ka tekanyo e lekanang ea litekanyetso le ho lekola kamehla mali le urine ea biochemical. Lithethefatsi leha e le life sehlopheng sena li ka khethoa mme tsa khethoa feela ke setsebi.

Bongata

Haeba ka phoso u feta tekanyetso e khothalletsoang le ho qala ha matšoao a tlhaselo ea hypoglycemic, o tlameha ho fana ka tharollo ea glucose (40% - 40-80 ml), kamora ho kenella ka tharollo ea glucose ea 5-10% o sebelisa infusion. Ka matšoao a bonolo, o ka phahamisa boemo ba tsoekere kapele ka sehlahisoa leha e le sefe se nang le sucrose kapa lik'habohaedreite tse bonolo.

Litlhahlobo mabapi le meriana ea lefu la tsoekere "Diabetesalong" li ntle haholo.

Mosebelisi Venera87 ea tsoang toropong ea Kursk tlhahlobisong http://otzovik.com/review_3106314.html o re sesebelisoa se thusitse beng ka eena ba tsofetseng ho laola maemo a bona a tsoekere. Moriana o ne o laetsoe litekanyetso tsa 30 mg hang ka letsatsi mme o ne a nkuoa ka kotloloho joalo ka ha a laetsoe ke ngaka. Ha ho litla-morao tse fumanoeng nakong ea kalafo.

Vitaly Koval le eena o bua ka mokhoa o nepahetseng ka sethethefatsi sena mme o re matlapa a thusitse nkhono'ae ho sebetsana le tsoekere e sa khaotseng (https://health.mail.ru/drug/diabetalong/).

Empa Ivan, ka lehlakoreng le leng, o re moriana o ne o sa tšoanele ntate oa hae, mme khahlano le semelo sa kalafo, mokuli o ile a qala ho ba le bohloko bo boholo sebakeng sa mpa, ka lebaka leo kalafo e ileng ea tlameha ho emisoa matsatsi a 10 kamora ho qala ho nka matlapa (http: //www.imho24) .ru / khothatso / 57004 / # tekolo77231).

"Diabetesalong" - setlhare se lokelang ho laeloa ke lingaka feela se nang le lipalo le mofuta o ikemetseng. Haeba moriana o sa tšoanele mokuli ea itseng, o lokela ho bona ngaka le ho khetha moriana o nepahetseng haholoanyane oa hypoglycemic.

Boloka kapa u arolelane:

Diabetalong ho la Moscow

Oral hypoglycemic drug, e fumanoang molomong oa bobeli.

E hlohlelletsa secretion ea insulin ke manyeme, e theola boemo ba tsoekere maling, e matlafatsa sephetho sa "glucose" le ho boloka kutloelo-bohloko ea lisele tsa pherekano ho insulin. Kamora kalafo ea lilemo tse peli, bakuli ba bangata ha ba hlaole ba lekhoba la lithethefatsi (keketseho ea boemo ba insulin le secretion ea C-peptides e ntse e tsoela pele).

Fokotsa nako ea ho qalella ho tloha motsotso oa ho ja ho isa ho qala ho secretion.

E khutlisa tlhoro ea pele ea "insulin secretion" ho arabela tekanyo ea tsoekere (ho fapana le lits'oants'o tse ling tsa sulfonylurea, tse nang le phello e kholo nakong ea bobeli ea secretion).

E boetse e ntlafatsa karolo ea bobeli ea seculin ea insulin. Fokotsa tlhoro ea hyperglycemia kamora ho ja (e fokotsa "hypprousial hyperglycemia").

Glyclazide e eketsa kutloisiso ea lithane tsa peripheral ho insulin (i.e., e na le phello e boletsoeng ea extrapancreatic). Ho mesifa ea mesifa, phello ea insulin mabapi le tsoekere ea tsoekere, ka lebaka la kutloisiso e ntlafalitsoeng ea lisele ho insulin, e eketseha haholo (ho fihla ho + 35%), hobane glycazide e phahamisa tšebetso ea mesifa ea glycogen synthetase.

Fokotsa sebopeho sa tsoekere maling, ho etsa hore boleng ba tsoekere bo potlakileng.

Ntle le ho ama metabolism ea carbohydrate, gliclazide e ntlafatsa microcirculation.

Lithethefatsi li fokotsa kotsi ea thrombosis e nyane ea sekepe, e susumetsa mekhoa e 'meli e ka amehang ho nts'etsopele ea mathata a lefu la tsoekere: karohano e sa lekanyetsoang ea lintho tse kopanyang liplatelete le ho khomarela le ho fokotseha hoa khatello ea lintlha tsa ts'ebetso ea liplatelete (beta-thromboglobulin, thromboxane B2), hammoho le ho khutlisetsoa ha methapo ea methapo. vascular endothelial shughuli le tšebetso e eketsehang ea activator ea plasminogen.

Glyclazide e na le thepa ea antioxidant: e fokotsa sekhahla sa lipid peroxides ho plasma, e eketsa ts'ebetso ea diselutase ea mali a khubelu ea mali.

Ka lebaka la litšobotsi tsa foromo ea litekanyetso, lethal dose ea letsatsi le letsatsi ea matlapa a Diabetalong® 30 mg e fana ka phekolo e sebetsang ea "gliclazide" plasma ea mali ka lihora tse 24.

Kamora ho tsamaisoa ka molomo, gliclazide e kenella ka botlalo ho tsoa ho tšilo ea lijo. Ho ja ha ho ame ho monya.

Ho bokellana ha ntho e sebetsang plasma ea mali butle-butle ho eketseha butle-butle, ho fihla bophahamong ebe ho fihla setsing sa lihora tse 6 ho isa ho tse tšeletseng ka mor'a ho nka moriana. Phapang ea motho ka mong e tlaase haholo.

Kamano lipakeng tsa lethal dose le mokokotlo oa moriana ho plasma ea mali ke ho itšetleha ka nako ka nako.

Tsamaiso le metabolism

Plasma protein e tlamang ke hoo e ka bang 95%.

E tšeloa ka har'a sebete 'me e hloekisoa haholo ke liphio. Ha ho na metabolites e sebetsang ho plasma.

Excretion ke liphio e etsoa haholo ka sebopeho sa metabolites, ka tlase ho 1% ea lithethefatsi ha li sa fetoloa.

T1 / 2 ke lihora tse ka bang 16 (lihora tse 12 ho isa ho tse 20).

Pharmacokinetics maemong a khethehileng a kliniki

Bathong ba tsofetseng, ha ho liphetoho tse bohlokoa tsa kliniki maemong a pharmacokinetic li bonoang.

- Type 2 lefu la tsoekere le kopantsoe le kalafo ea ho ja le ho ja lijo tse sa lekaneng le boikoetliso.

Setlhare se etselitsoe phekolo feela. tsa batho ba baholo.

Diabetesalong® 30 mg litafole tse lokolotsoeng tsa meriana li nkuoa ka molomo nako e le 1 / letsatsi nakong ea lijo tsa hoseng.

Bakeng sa bakuli ba sa kang ba fumana kalafo (ho kenyeletsoa le bakeng sa batho ba fetang 65), tekanyetso ea pele ke 30 mg. Ebe mokelikeli o khethoa ka bonngoe ho fihlela phello ea kalafo e lakatsehang e fihlellehe.

Khetho ea moriana e lokela ho etsoa ho ipapisitse le boemo ba tsoekere maling maling ka mor'a ho qala kalafo. Phetoho e 'ngoe le e' ngoe ea kokoana-hloko e latelang e ka etsoa kamora bonyane libeke tse peli.

Tekanyetso ea letsatsi le letsatsi ea lithethefatsi e ka fapana ho tloha ho 30 mg (1 tab.) Ho 90-120 mg (3-4 tab.). Tekanyetso ea letsatsi le letsatsi ha ea lokela ho feta 120 mg (matlapa a 4).

Diabetesalong® e ka nkela matlapa a tloaelehileng a gliclazide (80 mg) litekanyetso tsa matlapa a 1 ho isa ho a 4.

Haeba u fetoa ke tekanyetso e le 'ngoe kapa tse' maloa tsa moriana, u ke ke ua nka tekanyetso e phahameng ka tekanyetso e latelang (ka le hlahlamang).

Ha u nkela lithethefatsi tse ling tsa hypoglycemic lipilisi tsa Diabetalong® 30 mg, ha ho hlokahale nako ea phetoho. U lokela ho qala ka ho khaotsa ho sebelisa tekanyetso ea letsatsi le letsatsi ea lithethefatsi tse ling ebe ka letsatsi le hlahlamang qala ho sebelisa moriana ona.

Haeba mokuli a kile a fumana kalafo ka sulfonylureas e nang le bophelo bo bolelele ba bophelo, ho hlokahala hore ho be le tlhokomelo ka hloko (ho lekola tsoekere ea mali) bakeng sa libeke tse 1-2 ho latela sephetho sa litlamorao tsa kalafo e fetileng.

Diabetalong® e ka sebelisoa hammoho le li-biguanides, alpha glucosidase inhibitors kapa insulin.

Bakuli ba nang le bonolo le ba ho leka-lekanya a ho hloleha ha reisal moriana o laetsoe ka tekanyetso e lekanang le ea bakuli ba nang le ts'ebetso e tloaelehileng ea renal. Ho ho hloleha ho matla ha renal Diabetesalong® e kopantsoe.

Ho bakuli ba kotsing ea ho ba le hypoglycemia (phepo e sa lekaneng kapa e sa leka-lekanang, mathata a endocrine a tebileng kapa a sa sebetseng hantle - ho hloka khaello ea phepo le adrenal, hypothyroidism, ho hlakoloa ha glucocorticosteroids kamora ho tsamaisoa ha nako e telele le / kapa tekanyetso e phahameng, mafu a matla a tsamaiso ea methapo ea pelo / lefu la pelo le matla la coronary, carotid arteriosulinosis e atileng, atherosulinosis /) ho kgothaletswa ho sebelisa tekanyetso e fokolang (30 mg 1 nako / letsatsi) ea moriana Diabetalong®.

Hypoglycemia (e khahlanong le mofuta oa litekanyetso le lijo tse sa lekaneng): ho opeloa ke hlooho, mokhathala, tlala, ho fufuleloa, bofokoli bo matla, ho akheha, ho teba ha khatello ea mali, ho otsela, ho hloka boroko, ho ferekana, ho tšoenyeha, ho teneha, ho tsepamisa maikutlo, ho se khone ho tsepamisa mohopolo le ho lieha ho arabela, khatello ea maikutlo, pono e sa sebetseng, aphasia , ho thothomela, paresis, ho ferekana kelellong, ho tsekela, ho ikutloa u se na thuso, ho lahleheloa ke boitšoaro, ho nyekeloa, ho putlama, ho hema ka thata, bradycardia, ho felloa ke kelello, ho akheha.

Ho tsoa ts'ebetsong ea tšilo ea lijo: ho nyekeloa ke pelo, ho hlatsa, lets'ollo, ho opeloa ke mpa, ho ruruha (ho teba ha matšoao ana ho fokotseha ha ho nkuoa ka lijo), ka seoelo - ts'ebetso ea sebete e sa foleng (hepatitis, mosebetsi o eketsehileng oa hepatic transaminase, alkaline phosphatase, cholestatic jaundice - e hloka ho tlosoa hoa lithethefatsi).

Ho tsoa lithong tsa hemopoietic: inhibition of marrow hematopoiesis (phokolo ea mali, thrombocytopenia, leukopenia, granulocytopenia).

Litla-morao: pruritus, urticaria, lekhopho la letlalo, ho kenyeletsoa maculopapular and bullous), erythema.

Tse ling: ho sitisoa hoa pono.

Litla-morao tse tloaelehileng tsa sulfonylureas: erythropenia, agranulocytosis, hemolytic anemia, pancytopenia, allergic vasculitis, lefu le fokolisang sebete.

Contraindication

- mofuta oa 1 lefu la tsoekere

- lefu la tsoekere ketoacidosis, lefu la tsoekere, lefu la tsoekere,

Ho hloleha ho matla ha masapo le / kapa ho se sebetse hantle ha sebete,

- lilemo ho isa ho 18

- Nako ea ho anyesa (ho anyesa),

- congenital lactose ts'oarello, khaello ea lactase kapa lefu la glucose-galactose malabsorption,

- Hypersensitivity ho gliclazide kapa mang kapa mang ea fumanang lithethefatsi, ho tse ling tse tsoang ho sulfonylurea, ho sulfonamides.

Ha ho khothalletsoe ho sebelisa lithethefatsi ka nako e le 'ngoe hammoho le phenylbutazone kapa danazole.

Le tlhokomeliso: botsofali, khaello e sa lekanyetsoang le / kapa e sa leka-lekanang, mafu a matla a tsamaiso ea pelo (ho kenyeletsa le lefu la pelo, atherosclerosis), hypothyroidism, ho hlaka kapa ho hloleha hoa setho, ho hloka kalafo le / kapa ho se sebetse ha sebete, kalafo ea nako e telele le corticosteroids, botahoa, ho haella. glucose-6-phosphate dehydrogenase.

Bokhachane le pelehi

Ha ho na boiphihlelo ka gliclazide nakong ea kemolo. Lintlha tse mabapi le tšebeliso ea tse ling tse tsoang sulfonylurea nakong ea kemaro li na le moeli.

Boithutong ba liphoofolo tse sebelisoang ka laboratoring, litla-morao tsa "gliclazide" ha li so tsejoe.

Ho fokotsa kotsi ea tšoaetso ea tlhaho ea tlhaho, ho hlokahala hore ho laoloe hantle (kalafo e nepahetseng) ea lefu la tsoekere.

Lithethefatsi tsa molomo tsa molomo nakong ea kemolo ha li sebelisoe. Moriana oa khetho bakeng sa kalafo ea lefu la tsoekere ho basali baimana ke insulin. Ho khothalletsoa ho nka sebaka sa ts'ebeliso ea lithethefatsi tsa molomo tsa hypoglycemic ka kalafo ea insulin ka bobeli nakong ea kemaro e reriloeng, le hore na ho ima ho etsahetse ha u ntse u sebelisa moriana.

Ka ho nahana ka ho haella ha tlhaiso-leseling mabapi le tšebeliso ea gliclazide ka lebese la matsoele le kotsi ea ho ba le neonatal hypoglycemia, letsoele le hanyetsoa nakong ea kalafo ea lithethefatsi.

Sebelisa ho bana

E kopantsoe le bana ba ka tlase ho lilemo tse 18.

Matšoao hypoglycemia, letsoalo le sa bonahaleng, ho ferekana kelellong.

Phekolo: haeba mokuli a hlokometse, nka tsoekere ka hare.

Mohlomong nts'etsopele ea maemo a matla a hypoglycemic, e tsamaeang le komisi, ho akheha kapa mathata a mang a methapo ea methapo. Haeba matšoao a joalo a hlaha, ho hlokahala tlhokomelo ea tšohanyetso ea bongaka le ho kena sepetlele hang-hang.

Haeba hypoglycemic coma e belaelloa kapa e fumanoa, 50 ml ea tharollo ea glucose ea 40% e kenella ka potlako ho mokuli. Ebe tharollo ea 5% dextrose (glucose) e fanoa ka har'a methapo e le hore ho boloka sekhahla se hlokahalang sa tsoekere maling.

Kamora ho hlaphoheloa kelellong, ho bohlokoa ho fa mokuli lijo tse nang le lik'habohaedreite tse bonolo tse tsoang habonolo (molemong oa ho qoba tsoelopele ea hypoglycemia).

Ho lekola ka hloko maemo a tsoekere ea mali le ho hlahloba mokuli ho lokela ho etsoa bonyane lihora tse 48 tse latelang.

Kamora nako ena ea nako, ho latela boemo ba mokuli, ngaka e eang e nka qeto ea tlhoko ea tlhahlobo e ngoe hape.

Ho buoa ka methapo ha ho na thuso ka lebaka la ho tlangoa ha gliclazide liprotheine tsa plasma.

Glyclazide e ntlafatsa phello ea li-anticoagulants (warfarin); tokiso ea li-anticoagulant e ka hlokahala.

Miconazole (e nang le tsamaiso ea methapo le ha o sebelisa li-gel ho mucosa ea molomo) e ntlafatsa phello ea hypoglycemic ea lithethefatsi (hypoglycemia e ka ba ho fihla ho komisi).

Phenylbutazone (tsamaiso ea methapo) e ntlafatsa phello ea hypoglycemic ea lithethefatsi (maqhubu ka lebaka la liprotheine tsa plasma le / kapa e liehisa ho tsoa 'meleng), taolo ea tsoekere ea mali le tokiso ea litekanyetso tsa glyclazide lia hlokahala, ka bobeli nakong ea tsamaiso ea phenylbutazone le ka mor'a ho tlohela.

Lithethefatsi tse nang le ethanol le ethanol li ntlafatsa hypoglycemia, tse thibelang karabelo e lumellanang, li ka kenya letsoho kholisong ea komello ea hypoglycemic.

Ha e nkuoa ka mokhoa o ts'oanang le lithethefatsi tse ling tsa hypoglycemic (insulin, acarbose, biguanides), beta-blockers, fluconazole, ACE inhibitors (Captopril, enalapril), histamine H2 receptor blockers (cimetidine), MAO inhibitors, hypoglycemic le sulfanilamides mme e tšoailoe kotsi ea hypoglycemia.

Ka tšebeliso e kopanang le danazol, phello ea lefu la tsoekere e hlokomeleha. Hoa hlokahala ho laola boemo ba tsoekere ea mali le ho ntlafatsa tekanyetso ea gliclazide, ka bobeli nakong ea tsamaiso ea danazol le ka mor'a ho tlohela.

Chlorpromazine ka tekanyetso e phahameng (ho feta 100 mg / ka letsatsi) e eketsa sethala sa glucose maling, e fokotsa sekhahla sa insulin. Hoa hlokahala ho laola tsoekere ea mali le ho ntlafatsa tekanyetso ea gliclazide, ka bobeli nakong ea tsamaiso ea chlorpromazine le ka mor'a ho tlohela.

GCS (systemic, intraarticular, external, rectal management) e eketsa tsoekere ea mali ka nts'etsopele ea ketoacidosis (ho fokotseha ha mamello ho lik'habohaedreite). Hoa hlokahala ho laola tsoekere ea mali le ho ntlafatsa tekanyetso ea gliclazide ka bobeli nakong ea tsamaiso ea GCS le kamora ho itokolla.

Ritodrine, salbutamol, terbutaline (iv) e eketsa tsoekere ea mali. Ho khothalletsoa taolo ea tsoekere ea mali 'me, haeba ho hlokahala, phetisetso ea mokuli ho ea kalafo ea insulin.

Lipehelo tsa Maemo a Phomolo ea meriana

Setlhare ke ngaka.

Lipehelo le maemo a polokelo

Lethathamo B. Setlhare se lokela ho bolokoa sebakeng se ommeng le se lefifi, hore se fihle ho bana ka mocheso o sa feteng 25 ° C. Bophelo ba Shelf ke lilemo tse 3.

Sebelisa bakeng sa ts'ebetso ea sebete e sa sebetseng

Ka temoso mabapi le ho hloleha ha sebete.

- Ho ba le bothata bo matla ba renal le / kapa ho senyeha ha sebete.

Sebelisa bakeng sa ts'ebetso ea renal e senyehileng

Bakuli ba nang le bonolo le ba ho leka-lekanya a ho hloleha ha reisal moriana o laetsoe ka tekanyetso e lekanang le ea bakuli ba nang le ts'ebetso e tloaelehileng ea renal. Ho ho hloleha ho matla ha renal Diabetesalong® e kopantsoe.

Sebelisa ho bakuli ba tsofetseng

Bakeng sa bakuli ba sa kang ba fumana kalafo (ho kenyeletsoa le bakeng sa batho ba fetang 65), tekanyetso ea pele ke 30 mg. Ebe mokelikeli o khethoa ka bonngoe ho fihlela phello ea kalafo e lakatsehang e fihlellehe.

Phekolo e etsoa feela hammoho le lijo tse nang le khalori e tlase e tlaase.

Hoa hlokahala hore kamehla u lekole boemo ba tsoekere maling maling ka mpeng e se nang letho le ka mor'a ho ja, haholo-holo matsatsing a pele a kalafo le moriana.

Diabetesalong® e ka fuoa feela bakuli ba fumanang lijo khafetsa, tseo hangata li kenyelletsang lijo tsa hoseng 'me li fana ka phepo e lekaneng ea lik'habohaedreite.

Ha u fana ka litlhare, ho lokela ho hopoloa hore ka lebaka la tšebeliso ea likhakanyo tsa sulfonylurea, hypoglycemia e ka ba teng, 'me maemong a mang e le ka mokhoa o thata le o tšoarellang, o hlokang ho kenngoa sepetlele le taolo ea tsoekere ka matsatsi a' maloa. Hypoglycemia hangata e hlaha ka ho ja lijo tse nang le khalori e tlase, ka mor'a ho ikoetlisa nako e telele kapa ho ikoetlisa ka mor'a ho noa joala kapa ka ho sebelisa lithethefatsi tse 'maloa tsa hypoglycemic ka nako e le' ngoe.

Bakeng sa ho qoba nts'etsopele ea hypoglycemia, ho hlokahala hore ho khethoe litekanyetso ka hloko le ka bomong, hammoho le ho fa mokuli tlhaiso-leseling e phethahetseng ka kalafo e boletsoeng.

Ka ho ikoetlisa ho feta tekano mmeleng le maikutlong, ha u fetola mokhoa oa ho ja, ho hlokahala hore u fetole litekanyetso tsa lithethefatsi Diabetesalong®.

Haholo-holo a amehang ka ketso ea lithethefatsi tsa hypoglycemic ke batho ba tsofetseng, bakuli ba sa fumaneng lijo tse nang le phepo e nepahetseng, ba nang le boemo bo fokolang ba kakaretso, bakuli ba nang le pituitary-adrenal insuffanele.

Beta-blockers, clonidine, reserpine, guanethidine e ka pata lipontšo tsa kliniki tsa hypoglycemia.

Bakuli ba lokela ho lemosoa ka kotsi e eketsehang ea hypoglycemia maemong a ethanol, NSAIDs, le tlala.

Tabeng ea ethanol (joala), ho boetse ho khonahala ho ba le discriram-syndrome (bohloko ba ka mpeng, ho nyekeloa ke pelo, ho hlatsa, hlooho).

Ho kenella ka matla le ho lemala ho hoholo, ho chesa haholo, mafu a tšoaetsanoang a nang le febrile syndrome ho ka hloka ho felisoa ha litlhare tsa hypoglycemic tsa molomo le tumellano ea kalafo ea insulin.

Nts'etsopele ea khatello ea bobeli ea lithethefatsi e ka etsahala (e tlameha ho khetholloa ho ea mantlha, moo moriana o sa feng phello e lebelletsoeng ea kliniki nakong ea kopano ea pele).

Khahlano le semelo sa kalafo sa lithethefatsi Diabetalong®, mokuli o tlameha ho tlohela tšebeliso ea lino tse tahang le / kapa lithethefatsi tse nang le ethanol le lihlahisoa tsa lijo.

Nakong ea kalafo le Diabetalong®, mokuli o lokela ho tseba khafetsa litekanyetso tsa tsoekere le glycosylated hemoglobin maling, le litlatsetso tsa "glucose" ka har'a moroto.

Tšusumetso ho bokhoni ba ho khanna makoloi le litsamaiso tsa taolo

Nakong ea kalafo, tlhokomelo e lokela ho nkuoa ha ho khannoa likoloi le ho etsa lintho tse ling tse ka bang kotsi tse hlokang ho tsepamisa mohopolo le ho potlakisa karabelo ea psychomotor.

Diabetesalong - litaelo tsa tšebeliso

Lefu la tsoekere ke lefu le sa phekoleheng. Mokuli o qobelloa ho nka meriana e laolang tsoekere ea mali bophelong bohle ba hae.

Bakeng sa bakuli ba nang le lefu la tsoekere la mofuta oa 1, ena ke insulin, 'me mofuta oa bobeli ke lithethefatsi tse thehiloeng ho sulfonylurea.

Diabetesalong ke sethethefatsi sa hypoglycemic se fuoeng batho ba nang le tsoekere e ngata ea mali ho se fokotsa.

Setlhare se nooa ka molomo, 'me ka lebaka la ketso ea nako e telele, se sebelisoa ka makhetlo a 2 ka letsatsi.

Setlhare se fanoa e le sesebelisoa se ikemetseng kapa ka har'a mokhoa oa kalafo o kopaneng. E sebelisoa maemong ao ho latela mokhoa oa ho ja ho sa thuseng, empa ho a nwa moriana ho lokela ho tsamaea le khalemelo ea phepo e nepahetseng.

Sebopeho, foromo ea tokollo

Diabetesalong e fumaneha ka tsela ea matlapa a tšoeu a chitja. Li tletse mekotla ea likotoana tse 10 le lebokose la karete, moo ho nang le lipalo tse 3 ho isa ho tse 6.

Setlhare se fumaneha ka litekanyetso tse peli: 30 mg le 60 mg ea ntho e sebetsang, e leng gliclazide.

Likarolo tse thusang tsa sethethefatsi:

• colloidal silicon dioxide,
• lactose monohydrate,
• calcium stearate
• pyromellose
• talcum phofo.

Foromo ea litekanyetso e ka ba ka mokhoa oa matlapa a nang le tlhahiso e lokisitsoeng kapa ka ketso ea nako e telele.

Pharmacology le pharmacokinetics

Motsoako o ka sehloohong oa ts'ebetso ke gliclazide, ka tlhaho ea lik'hemik'hale e tsoa ho sulfonylurea ea bobeli. Gliclazide e bonts'a ts'ebetso e phahameng ea ho khetha le bioavailability.

E hanyetsana le libaka tse fapaneng tsa tlhaho mme e na le litlamorao tse latelang:

• e eketsa tlhahiso ea insulin ea hau, 'me e u lumella ho fokotsa tekanyetso ea li-hormone tse tsoang.
• normalizing metabolism ea carbohydrate,
• e eketsa tšebetso ea lisele tsa pancreatic beta,
• e fokotsa masapo a mmele, a thibelang thrombosis le li-pathologies tse ling tsa methapo.

Diabetesalong e kenella ka botlalo ka mor'a taolo. Butle-butle ho bokella maling, ho fihla maemong a mangata kamora lihora tse 4-6 kamora ts'ebetso, ho bonts'a phello ea eona bakeng sa lihora tse 10-12, ebe khatello ea eona e fokotseha haholo mme kamora lihora tse 12 moriana o tlosoe ka botlalo mmeleng.

Gliclazide e tšeloa haholo-holo ke sebete, 'me e entsoe ke liphio.

Matšoao le contraindication

Lebaka la ho nka lefu la tsoekere ke tlhahlobo ea lefu la mokuli - lefu la tsoekere la mofuta oa 2. Moriana o laetsoe ho theola tsoekere ea mali ha ho latela lithibelo tsa lijo tse khothalletsoang.

Hape, moriana o fanoa e le prophylactic bakeng sa mathata a bakoang ke lefu la tsoekere, haholo-holo liphetoho sebopeho sa methapo ea mali tlasa ts'usumetso ea "glycemia" e phahameng.

Ho na le li-contraindication bakeng sa moriana, li kenyeletsa:

• mofuta oa 1 lefu la tsoekere
• ho nka miconazole,
• ho hloleha ho matla ha hepatic le renal,
• nako ea kemaro le kanyeso,
• ho ba teng ha lefu la tsoekere ketoacidosis, komisi kapa thoroma,
• kutloisiso e phahameng ea likarolo tse etsang moriana,
• tlolo ea metabolism ea lactose,
• lilemo ho isa ho motho e moholo.

Tlhokomeliso mme e sebelisoa feela ke tlhokomelo ea ngaka, moriana o sebelisoa:

• botsofaling
• batho bao lijo tsa bona li sa hlakoheng,
• bakuli ba nang le lefu la pelo,
• bakuli ba nang le khaello ea glucose-6-phosphate dehydrogenase,
• kamora kalafo ea nako e telele ea glucocorticosteroid,
• lekhoba la tahi
• ho ba le ho hloleha ha meno kapa sebete.

Maemong ana, ngaka e tlameha ho etsa qeto motheong oa data e fumanehang.

Lintho tsa video tse tsoang ho li-pharmacologists:

Bakuli ba khethehileng

Bakeng sa batho ba baholo ba fetang 65, ho ka hlokahala phetoho ea litekanyetso. Ka kakaretso, moriana o sebelisoa ho latela melao e ts'oanang.

Nakong ea kemaro, moriana o khothalletsoa hore o nkeloe phekolo ea insulin ho fihlela pelehi. Ha ho na boiphihlelo ka tšebeliso ea lefu la tsoekere le lithethefatsi tse ling tse thehiloeng glycoside nakong ea kemolo, ka hona ho ke ke ha khonahala ho tseba hore na phello ea eona ke efe ho lesea.

Nakong ea lebone, sethethefatsi le sona ha se khone ho sebelisoa, hobane ho na le monyetla oa ho holisa neonatal hypoglycemia ho ngoana. Ka hona, ho anyesa mosali ea kulang ho thibetsoe.

Bakuli ba nang le bothata ba ho phekoloa ka methapo le methapo e meng ea methapo ba lokela ho latela litekanyetso tse tlase, haholo-holo, ba lokela ho lula ba beiloe leihlo ke ngaka e ba teng.

Litaelo tse khethehileng

Boemo ba bohlokoa ba ho nka lefu la tsoekere ke phepo e tloaelehileng. E lokela ho latela litlhahiso tsa sehlopha sena sa bakuli mme e lokisoe ka nako. Sena se hlokahala ho felisa kotsi ea hypoglycemia, e ka hlahang ka lebaka la khaello ea mohloli oa matla maling.

Mabaka a tlatsetsang ho hlaha hoa hypoglycemia e ka ba:

• ho hloka leihlo la mokuli ka boemo ba hae,
• ho se shebe mefuta ea mekhoa ea ho ja le ho ja, tlala, lijo tse sa lokisoang hantle,
• ho hloleha ha liphio kapa sebete,
• lithethefatsi tse ngata
• maloetse a endocrine,
• ho se sebetse hantle ha boemo ba ts'ebetso ea 'mele le palo ea lik'habohaedreite tse fumanoeng,
• taolo e tšoanang ea lipilisi tse 'maloa.

Litla-morao le ho sebelisa overdose haholo

Litlamorao tse kholo tsa ho noha moriana ke:

• hlooho e bohloko
• hemolytic mofuta anemia,
• tlolo ea tatso
• allergies, hangata e hlaha ka sebopeho sa lekhopho la letlalo.

Matšoao a mang a ka hlaha:

• cramps
• ho tsekela
• tlolo ea kutlo ea kutlo
• ho thothomela
• tlolo ea mosebetsi oa ho hema le ho koenya,
• khatello ea eketseha
• boleng bo fokotsehileng ba pono
• hepatitis ea mofuta oa cholestatic.

Tabeng ena, ho hlokahala hore o khaotse ho sebelisa lithethefatsi ebe o khetha li-analogu tse thehiloeng likarolong tse ling.

Ho sebelisa lithethefatsi tse ngata ho feta tekano ho ka etsahala haeba u ikemela ho feta tekanyo ea meriana e nooang. Liphello tsa eona tse ka sehloohong ke hypoglycemia, ho fihlela ho akheha.

Ka hypoglycemia e sa koaheloang, lethal dose le lokela ho fokotsoa, ​​'me palo ea lik'habohaedreite lijong e lokela ho eketsoa. Tabeng ea hypa ea hypoglycemic, ho fanoa ka tharollo ea glucose e kenang.

Ho sebelisana le meriana e meng

Diabetesalong e sebelisana ka mafolofolo le lintho tse ngata, ka hona, pele u e nka, u lokela ho tloaela ntlha ena.

Kahoo, haeba o ka sebetsa ka nako e le 'ngoe:

• ka joala bo ka baka hypoglycemia,
• le Danazol, phello ea lefu la tsoekere e bonahatsoa, ​​e fokotsang phello ea lithethefatsi,
• ka miconazole, phello ea gliclazide e matlafalitsoe, e ka tlatsetsang ho theheng ha hypoglycemia, ntho e tšoanang e etsahala le baemeli ba bang ba hypoglycemic,
• le chlorpromazine, e fokotsang tlhahiso ea insulin, ts'ebetso ea lithethefatsi e fokotsehile haholo,
• ka tetracosactide le glucocorticosteroids ho ka lebisa nts'etsopele ea ketoacidosis le ho fokotseha ha mamello ea carbohydrate,
• le Wafarin le li-coagulants tse ling li ntlafatsa phello ea eona.

Tlhahlobo ea lingaka e bonts'a hore Diabetesalong e sebetsa hantle haholo ho fokotsa tsoekere ea mali, leha ho le joalo, e ke ke ea sebelisoa kamehla.

Maemong ana, ho fanoa ka li-analogues tsa Diabetesalong, tse ngata haholo:

Diabetesalong le Diabeteson li ntshetswa pele motheong oa motsoako o tšoanang, empa moriana oa bobeli o nkuoa o sebetsa hantle ho feta, hobane phello ea ketso ea ona e fihlella ka potlako, empa theko ea sethethefatsi sena e phahame makhetlo a mabeli. Glyclazide ke analogue e batlang e felletse.

Glucophage nako e telele e na le metformin ka sebopeho sa eona mme e ka kopanngoa le insulin le lithethefatsi tse ling ho theola tsoekere ea mali.

E khothalelitsoe Lingoloa Tse Ling Tse Amanang

Taolo ea lefu la tsoekere

Ha ho bonolo kamehla ho laola mofuta oa tsoekere ea lefu la tsoekere la 2 feela ka thuso ea lijo tse bobebe tsa carb le mojaro o boima oa mesifa. 'Me hoa hlokahala ho loants'a hyperglycemia, hobane kalafo e sa rutehang e baka mathata a maholo.

A mang a a kotsi haholo ke mathata a pelo le pelo. Diabetesalong (Latin Diabetalong), setlhare sa hypoglycemic se nang le nako e telele kapa se lokisitsoeng se tla thusa ho fokotsa kotsi ea ho ba le CVD.

Monyetla oa pharmacological

Melemo ea antidiabetesic ea lithethefatsi e bakoa ke karolo e sebetsang ea gliclazide. Matlapa a na le 30 kapa 60 mg ea motsoako oa mantlha le litlamorao: calcium stearate, hypromellose, talc, lactose monohydrate, colloidal silicon dioxide.

Diabetesalong ke setlhare sa sehlopha sa bobeli sa sulfonylurea.

Ha e kenella maling, gliclazide e phahamisa tlhahiso ea li-hormone tsa endo native ka cells-lisele tsa manyeme, e potlakisa ts'ebeliso ea tsoekere (e potlakisa mesifa ea glycogen synthase).

Matsatsing a 'maloa ho tloha ha ho qala thupelo, boemo ba glycemic bo tloaelehile. Nako ea ho kenella ho kenyelletsa lijo ka har'a tšilo ea lijo hore e hlahisoe ka insulin ea nako e telele e fokotsehile, 'me matšoao a ho fokola ha lijo a fokotsehile.

Hoa makatsa hore lilemo tse 2 kamora ho sebelisa moriana, khatello ea "insprandial insulin" le C-peptide e lula e le teng. Matla a amang 'mele a Diabetalong a rarahane:

• E laola metabolism ea carbohydrate,
• E na le li-antioxidant phello,
• E hlohlelletsa insulin,
• E na le phello ea hemovascular (suppress platelet aggregation).

Ha tsoekere e kena maling, gliclazide e potlakisa tlhahiso ea insulin. Ka kalafo e sa feleng, setlhare se lemosa:

• Mathata a Microvascular - retinopathy (ts'ebetso ea ho ruruha ho retina) le nephropathy (renal dysfunction),
• Liphetho tsa Macrovascular - stroke, ho otla ha pelo.

Litšobotsi tsa Pharmacokinetic

Ho tloha ka mpeng, sethethefatsi se kenngoa ka botlalo. Likahare tse phahameng maling a fihla ka mor'a lihora tse 2-6, le bakeng sa litafole tse nang le MV - lihora tse 6-12.

Phello ea kalafo e nka lihora tse 24, liprotheine tsa mali glycazide e tlama ho 85-99%. Sebeteng, sehlahisoa sa bioloji se fetoloa metabolites, e 'ngoe ea tsona e na le phello e ntle ho microcirculation. Bophelo ba halofo ke lihora tse 8-12, bakeng sa litafole tse nang le MB - 12-16 lihora. Setlhare se tlotsoa ka 65% ka moroto, ka 12% ka maro.

Litlamorao

Liphetho tse sa rateheng bakeng sa tšilo ea lijo e ka ba mathata a dyspeptic ka mokhoa oa ho nyekeloa ke pelo, ho hlatsa, bohloko ba ka mpeng. Ho tloha lehlakoreng la metabolism, hypoglycemia e ka etsahala, bakeng sa tsamaiso ea potoloho - eosinophilia, cytopenia, anemia. Ka lehlakoreng la letlalo, allergy le photosensitization lia khoneha. Ho tsoa lithong tsa kutlo ho na le likhathatso tsa tatso, hlooho e bohloko, tahlehelo ea tšebelisano, ho felloa ke matla.

Ho sebelisana le lithethefatsi

Ts'ebetso ea glycoside e ntlafatsoa ke ts'ebeliso e kopaneng ea anabolic steroid, ACE inhibitors, β-blockers, cimetidine, fluoxetine, salicylates, MAO inhibitors, Flucanazole, Pentoxifylline, Miconazole, Theophylline, Tetracycline.

Monyetla oa glyclozide o fokotseha ha o sebelisoa ka mokhoa o tšoanang le barbiturates, glucocorticoids, sympathomimetics, saluretics, rifampicin, lipilisi tsa thibelo ea bokhachane, li-estrogens.

U ka etsa kopo joang

Glycloside e lokela ho nkuoa ka tlhahiso ea lijo. Letlapa le metsoa kaofela, le hlatsuoa ka metsi ka mocheso oa kamore. The endocrinologist e khetha litlhare le mefuta ea kalafo ka bonngoe, ho latela sethala sa lefu lena le karabelo ea lefu la tsoekere ho moriana. Bakeng sa moriana Diabetalong, litaelo tsa tšebeliso li khothaletsa tloaelo ea ho qala ea 30 mg le khalemelo e eketsehileng ntlheng ea keketseho (haeba ho hlokahala).

Ho fihlella phello e matla ea kalafo, ho bohlokoa ho latela melao e bonolo.

1. Tekanyetso eohle ea letsatsi le letsatsi e nkuoa hang, ho molemo ho feta - hoseng,
2. Palo ea lithethefatsi e ka fetoloa nakong ea 30 -120 mg / ka letsatsi,
3. Haeba u hlolohetsoe nako ea ho amoheloa, u ke ke ua pheta tloaelo ka nako e latelang,
4. Ha a bala tekanyetso, ngaka e nahana ka ho balloa ha glucometer le HbAlc.

Ka ts'ebetso e sa lekaneng, ho tloaelehile ho eketseha (kamora tumellano le ngaka), empa eseng pele ho feta khoeli kamora hore ho nkuoe lethal la pele la glycoside. Libeke tse ling le tse ling tse 2, ka phello e sa foleng ea glycemia, o ka eketsa lethal dose.

Ho bohlokoa ho ela hloko hore Letlapa le le leng la Diabetesalong PV le na le 60 mg ea glyclazide, sena se tsamaisana le matlapa a 2 a Diabetalong MV 30 mg ka ngoe.

Ha ho fetisoa ha lefu la tsoekere ho gliclazide ho tsoa ho lithethefatsi tse ling tsa hypoglycemic, likhahla ha li hlokahale, ntle le melemo ea sulfonylurea. Tekanyetso ea pele ntlheng ena e tloaelehile - 30 mg, haeba endocrinologist ha e laetse morero oa hae.

Ka kalafo e rarahaneng, Diabetalong e sebelisoa hammoho le mefuta e fapaneng ea insulin, li-biagudins, li-inhibitors tsa cul-glucosidase. Ka tlhokomeliso, moriana o fuoa lingaka tsa lefu la tsoekere ho tsoa sehlopheng sa kotsi sa hypoglycemic (tšebeliso e mpe ea joala, mosebetsi o boima oa 'mele kapa lipapali, tlala, semelo se phahameng sa khatello ea maikutlo). Mesebetsi ea Hemopoietic e sitisoa ke nts'etsopele ea anemia, thrombocytopenia, leukopenia, granulocytopenia.

Litlhokahalo tsa polokeho

Bakeng sa ho qoba hypoglycemia, ho bohlokoa ho fana ka nako ea ts'ebeliso ea moriana bakeng sa ho ja, ho thibela likhefu tse kholo tsa lijo, ho felisa ka botlalo ts'ebeliso ea lino tse tahang. Tsamaiso e tšoanang ea li-β-blockers e ka sotha matšoao a hypoglycemia.

Boemo ba hypoglycemic bo ka lemohuoa ke hlooho e opang, mathata a ho hokahanya, litlhaselo tse sa laoleheng tsa tlala, khatello ea maikutlo, ho akheha, pono e fifalitsoeng, mathata a dyspeptic. Boitšoaro ba adrenergic bo boetse bo bonahatsoa: ho tšoenyeha, ho fufuleloa, marotholi a khatello ea mali, lefu la pelo la mokokotlo, pherekano ea morethetho oa pelo. Mathata a dyspeptic, ho tsitsipana hoa morethetho oa ho kheloha, le ho fetoha hoa letlalo (lekhopho, ho se khotsofale, erythema, urticaria, edincke's edema) ke tšobotsi.

Pheko e atlehang e ke ke ea khoneha ntle le lijo tse nang le carb e tlase. Ka lebaka la kotsi ea litlamorao, bakhanni ba lokela ho nka meriana ka hloko. Litlhahiso tse tšoanang li sebetsa ho baemeli ba liprofesa tse amanang le litheko tse phahameng le khatello ea maikutlo.

Pathologies ea sebete le li-ducts tsa bile li baka lefu la hepatitis, keketseho ea ts'ebetso ea enzyme.

Haeba motho ea hlokofalitsoeng a hlokometse, o hloka ho ja lipompong, ho noa khalase ea tee kapa ho hong ho nang le lik'habohaedreite tse ngata. Kamora hore boemo bo ntlafale, setsebi sa endocrinologist se hloka ho botsoa ho lokisa lethal dose kapa ho fetola moriana.

Menahano ea lithethefatsi

Ho latela karolo e sebetsang ea Diabetalong, analogue e tla ba sehlahisoa sa Glidiab se ka bang li-ruble tse ka bang 140. Lingaka li fa lithethefatsi tsa Diabeteson le Diabeteson MV litheko tse phahameng ho litheko ho tloha ho 286 ho isa ho 318 li-ruble. Bakeng sa litokisetso tse tšoanang, Glyclada le eona e ka khothaletsoa.

Litokisetso tse nang le phello e ts'oanang ea hypoglycemic joalo ka Amaril, Glimepiride, Glemaz, Glyurenorm li tla ba hantle ka sebopeho. Li etselitsoe hypersensitivity kapa li-contraindication tse ling bakeng sa glycoside.

Litlhahlobo tsa Diabetesalong

Litsebi tsa lefu la tsoekere tse boneng litlamorao tsa lefu la tsoekere, ho litekolo li hlokomela melemo ea lona:

• Ntlafatso ea butle-butle ea matšoao a glucometer,
• Ho tsamaisana hantle le meriana e meng,
• Litsenyehelo tse theko e tlaase tsa meriana
• Bokhoni ba ho theola boima ba 'mele nakong ea kalafo.

Ha se motho e mong le e mong ea khotsofalitsoeng ke tlhoko ea taolo ea glycemic ea khafetsa (hofihlella ka makhetlo a 5 ka letsatsi), empa ha nako e ntse e tsamaea, matšoao a eona a tsitsa le tlhoko ea taolo e ntlafalitsoeng ea fokotseha.

Ka kakaretso, Diabetesalong ke lithethefatsi tse ka tšeptjoang tsa lefu la ho fokola lefu le hlasimollang boemo ba bophelo ba glycemic hantle. Ha e sebelisoa hantle, e ka thibela liketsahalo tsa pelo le mathata a mang a tebileng a lefu la tsoekere la 2.