Cephalosporin IV motsoako oa lithibela-mafu o nang le bongata bo bongata ba ketso ea bactericidal. E sebetsa khahlanong le likokoana-hloko tsa gram ntle le gram. Matla a bactericidal a cefepime a bakoa ke ho sitisa motsoako oa leseli la baktheria. Cepepime e hanyetsana le li-act lactamase tse ngata. Ke bactericidal, ho kenyeletsa mefuta e mengata e hanyetsanang le penicillin kapa lithibela-mafu tse ling tsa cephalosporin. Cefepime ea sebetsa (joalo ka in vitrojoalo ho vivo) mabapi le likokoana-hloko tse latelang:
- Lifofane tse ntle tsa gram - Staphylococcus aureus (Mechini e hlahisang β-lactamase e sa hlahiseng 'mele ha e sebetse khahlano le methapo ea methapo e thibelang methane), S. epidermidis (ho kenyelletsa likarolo tse hlahisang β-lactamases), mefuta e meng ea staphylococci, ho kenyeletsoa S. hominis, S. saprophyticus, Streptococcus pyogene (Sehlopha sa Streptococcus A), S. bovis (sehlopha D) Li-virreans tsa Streptococcus,
- gram e mpe e sebetse - Acinetobacter calcoaceticus (subsp. Anitratus, lwoffi), Enterobacter spp.ho kenyelletsa E. aerogene, E. sakazakii, Escherichia coli, H. influenzae (ho kenyeletsoa β-lactamase e hlahisang lithane), H. parainfluenzae, Klebsiella spp.ho kenyelletsa K. pneumoniae, K. oxytoca, K. oxaenae, Moraxella cacarrhalis (Branhamella catarrhalis, ho kenyelletsa likarolo tse hlahisang β-lactamases), Morganella morganii,Proteus spp., ho kenyelletsa P. mirabilis, P. vulgaris, Pseudomonas spp.ho kenyelletsa P. aeruginosa, P. putida, P. stutzeri, Serratia (ho kenyeletsa S. marcescens,S. liquefaciens),
- anaerobes - Clostridium perfringens, Mobiluncus spp.
Mofumahali Cepepime e kenella ka botlalo ka mor'a taolo ea i / m.
Kamora tsamaiso e le 'ngoe ea i / m kapa iv bakeng sa nako ea khefu, ho tsepamisoa maikutlo a latelang a plasma ea banna ba phetseng hantle (μg / ml):

Matšoao a sebelisang phofo ea novapim

• ts'oaetso ea pampitšana ea urinary (e sa rarahanang ebile e rarahane)

• tšoaetso ea letlalo le lisele tse bonolo

• pneumonia

• tšoaetso ea intraabdominal

• feberu ea neutropenic

• nesep-zhynys shyғaru zholdarynyң (asқynғan zhne asқynbaғan) aurularynda

• terі zhne zhmsaқ tіnderdің zhpalarynda

• pneumonia

• intra-abdominal dzhpalard

• Nutropenials қyzbada

Contraindication novapima phofo

• hypersensitivity hang-hang ho nako ea khefu, L-arginine (ho kenyelletsa li-cephalosporin tse ling, penicillin, lithibela-mafu tse ling tsa beta-lactam)

• bana ba ka tlase ho lilemo tse 12

• ho ima, ho nyeka

• mafu a ka mpeng: (ho kenyeletsa nalane ea), haholo-holo lefu la ho ruruha lera le sa foleng

• bayau tүrdegі cefepimge, L-arginine (onyң isіnde basқadai cephalosporing, penicill, lidocaring, basқaday beta-lactamdes antibioticterge) asқyn sezimtaldyta

• 12 jasқa deyingі balalarғa

• zhktіlіkte, lactation kesenіnd

• asқazan-ishek zholdarynyң aurularynda (onyң ishind syrtartқysy), әсіресе колитте

• auyr sozylmaly bүyrek zhetkіlіksіzdіgіnde

Litla-morao tsa phofo ea novapim

• ho thothomela ha anaphylactic, lekhopho la letlalo (ho kenyelletsa le rasiti erythematous), ho hlohlona, ​​feberu

• candidiasis ea mucosa ea molomo, tatso e khelohileng, ho nyekeloa, ho hlatsa, dyspepsia. Bohloko ba ka mpeng, lets'ollo, ho qhekella, colitis (ho kenyeletsa le pseudomembranous colitis)

• tachycardia, dyspnea, paripheral edema,

• hlooho e opang, ho tsekela, ho hloka boroko, paresthesia, matšoenyeho, pherekano, ho tsitsipana

• anemia, thrombocytopenia, leukopenia, neutropenia, pancytopenia, hemolytic anemia

• vaginitis

• mosebetsi o sa sebetseng oa renal

Setso sa lehae: tsamaiso ea i / v - phlebitis, ka i / m - hyperemia le bohloko sebakeng sa ente.

• hepatitis, cholestatic jaundice

• phlebitis le ho ruruha sebakeng sa ente ea intravenous, ho ruruha kapa bohloko sebakeng sa ente ea intravenous

• anaphylactic makala, teri burtpesі (ony іshіnde erythematous burtpeller), қyshu, қyzba

• auyz қuysy shyryshty қabyқynyң empazinda, dәm sezudің bұzyluy

• lets'ollo, Zhurek Ainuy, Usu, Ishatu, istuy auyruy, dyspepsia, pseudomembranous colitis

• tachycardia, shetkerg_is_nuller, dem_kpe

• bass auyruy, bass ainaluy, ұйқысыздық, parestesiyalar, masasyzdyқ sezіmі, sananyң shatasuy, құrysyular

• anemia, thrombocytopenia, leukopenia, neutropenia, pancytopenia, hemolytic қ anemia

• vaginitis

• бүйрек қызметінің бұзылуы

• hepatitis, cholestatic қ sary auyru

Litaelo tse khethehileng bakeng sa tšebeliso

Basқaday antibiotictermen бір мезгілде долданған к wearе allergies қ reactionar өршуінен сақ болу керек.

Bүyrek қyzmetі ayқyn bұzylғan nauқastarғa jeәne egde zhastғy nauқastarғa litokisetso tғayyndaғanda sabolu kerek. Bauyr zhne bүyrek қyzmetі ayқyn bұzyluy үirstken keda қan plasmasynda litokisetso ңanyғu deңgeyіn tұraқty anyқtau kerek. Emdeudi ұzartқan kebede bauyr jәne bүyrek қyzmet jaғdaylarynyң kөrsetkіshіn, shetkerg қandy mіndettі tүrde tұraқty baқylau kerek.

Tekanyetso le tsela ea tsamaiso

Bana ba lilemo li 12 ho isa ho 16 kapa ba boima ho fihlela ho 40 kg - mofuta o khothalletsoang oa litekanyetso bakeng sa matšoao ohle (ntle le febrile neutropenia) - 50 mg / kg nako le nako ka lihora tse 12, le febrile neutropenia - 50 mg / kg nako e 'ngoe le e' ngoe ka lihora tse 8. Tekanyetso e le 'ngoe e phahameng ha ea lokela ho feta 2 g. .

A ho hloleha ho phekola a renal tekanyetso e behiloe ho latela boteng ba ts'oaetso le tumello ea creatinine: ho feta 60 ml / Min - 0.5 g, 1 g, kapa 2 g, ka lihora tse 12 kapa 2 g ka nako e 'ngoe le e' ngoe lihora tse 8, CC 30-60 ml / min - 0.5 g, 1 g kapa 2 g, lihora tse ling le tse ling tse 24 kapa 2 g, lihora tse ling le tse ling tse 12, le QC 11-29 ml / metsotso - 0.5 g, 1 g kapa 2 g, lihora tse ling le tse ling tse 24, ka tlase ho 11 ml / min - 0,25 g, 0.5 g, kapa g, g, 1 g, lihora tse ling le tse ling tse 24. ho tsoala ho sa feleng ha nako le nako - ka makhetlo a 48, g, g, g, kapa 2 g, lihora tse ling le tse ling tse 48. Bakuli ba nang le hemodialysis ba fuoa 1 g ka letsatsi la 1, ebe 0.5 g e ngoe le e ngoe lihora tse 24 bakeng sa ts'oaetso eohle le 1 g lihora tse ling le tse ling tse 24 bakeng sa kalafo. febrile neutropenia. Ka letsatsi la hemodialysis, moriana o fanoa kamora ho fela ha semelo sa hemodialysis, ho bohlokoa hore o tsamaise nako ea cefepime letsatsi le leng le le leng ka nako e le 'ngoe.

Lintlha mabapi le ts'ebeliso ea lithethefatsi ho bana ba nang le bothata ba ho ba le methapo e sa sebetseng e sa feleng ha e fumanehe, leha ho le joalo, ha e fuoa li-pharmacokinetics tse tšoanang ho bana le batho ba baholo, mofuta oa litekanyetso (phokotso ea litekanyetso kapa keketseho ea nako lipakeng tsa tsamaiso) baneng e tšoana le mofuta oa litekanyetso ho batho ba baholo.

Bakeng sa tsamaiso ea methapo, qhala ka metsing a sa hlapolloang bakeng sa ente, tharollo ea 5% ea dextrose kapa tharollo ea sodium chloride ea 0,9% Bakeng sa tsamaiso ea methapo - ka metsing a sa hlapolloang bakeng sa ente, ka tharollo ea 0.5 le 1% ea lidocaine.

Matsatsi a 12-a 16 jasқa deіngі nemese dene salmaғy 40 kg dejn balalarғa - li-barls Ең жоғары біреттік lethal 2 g aspauy kerek. Емдеудің ұзақтығы ересектертегідей.

Sozylmaly bүyrek zhetkіlіksіzdіgіnde dosed ұқ ң ы ғ р ғ р р g 24r 24 saыat saın nemese 2 g әr 12 saғat saın, KK 11-29 ml / min - 0.5 g, 1 g nemesh 2 g 24r 24 saғat saın, 11 ml / min ke mang - 0,25 g, 0.5 g nemesé 1 g 24р 24 saғat saın, turats outpatients peritonealdialysis - 0.5 g, 1 g nemesis 2 g 48r 48 saғat saın. Hemodialysisdegemodelushelerge, 1-ea lilemo li 1 g, entsoe ka 0.5 g-nan barlyқ zhpalar үshіn әр 24 saғat saın zhne febrildi neutropenins emdeu үshіn 1 g 24r 24 saғat sayin .. Hemodialysis dzhergizgen kedeta, lithethefatsi hemodialysis mananeo ayatalnannan keyin enziedі, cefepimdі kүndde bir uaқytta engzzheng.

Sozylmaly bүyrek zhetkіlіksіzdіgі қatar zhretіn balalarda Litokisetso tsa Koldanu zhіnіndegі derekter - banna ba balalar rezekterdegі pharmacokinetikanyң ұқsastyғyn eskere otyryp, balalarda dosalau rezhimі (dosed azayte nemese engіzu arasyndaereseryu reyutyeretury).

Drugapap: litaelo tsa tšebeliso

Tsohle ka lefu la tsoekere »The lithethefatsi Novapim: litaelo tsa tšebeliso

Novapim ke lithibela-mafu tse pharalletseng tse sebelisoang ho phekola mafu a tšoaetsanoang a tsamaiso ea phefumoloho, genitourinary system le letlalo.

Ketso ea pharmacological

Sena ke setlhare sa antibacterial se sehlopha sa IV cephalosporins ea IV. E bontša ts'ebetso khahlano le likokoana-hloko tse ntle tsa gram le gram-negative. Ketso ea moriana ke ho liehisa lits'ebetso tse kahare ho membrane ea sele:

li-aerobes tse ntle tsa grame: Streptococcus vir> Novapim e bonts'a katleho e ntle khahlanong le likokoana-hloko tse ntle tsa gram le gram-negative.

Kamora ho tsamaisoa, sethethefatsi se tsamaisoa ka botlalo mmeleng ohle. Ts'oarello ea plasma e latela lilemo tsa mokuli le bong ba hae. Pheko ea kalafo ea cefepime kamora hore e kenngoe ente e le 'ngoe e kenngoe ka har'a mokokotlo, mokokotlo, secretion e hlahisoang ke bronchi, liseleng tse bonolo tsa "prostate gland" le "appendicitis". Peresente ea ho tlama hoa vaerase ho liprotheine tsa plasma e fihla ho 19%.

Nako e hlokahalang bakeng sa halofo ea bophelo e ka ba lihora tse peli, ho sa tsotelehe litekanyetso. Excretion e tsoang 'meleng e etsoa ka ho sefa serethe se bitsoang renal glomeruli, hoo e ka bang 85% ea nako ea konkrese e ntšoa' meleng ka moroto.

U ka nka Novapim joang?

Liente tsa antibiotic li fanoa ka mokhoa oa methapo kapa methapo. Tekanyetso le tsela ea tsamaiso li beoa ka bonngoe.

Tekanyo e khothalletsoang ea karolelano ea bakuli ba baholo:

• ts'oaetso ea genitourinary system, ho sa tsotelehe ho teba: ho tloha ho 500 mg ho isa ho 1 g, ente intramuscularly kapa intravenly ka lihora tse ling le tse ling tse 12,
• maloetse a letlalo: 2 g ka methapo le nako ea lihora tse 12,
• tšoaetso ea lisele tse bobebe: 2 g, ka makhetlo a mabeli ka letsatsi,
• pneumonia: ho tloha ho 1 ho isa ho 2 g, kahare ho lihora tse ling le tse ling tse 12,
• tšoaetso ea ka mpeng: 2 g, kahare,
• kalafo ea febrile neutropenia: 2 g, kahare ho lihora tse ling le tse ling tse robeli.

Liente tsa antibiotic li fanoa ka mokhoa oa methapo kapa methapo.

Ho sebelisa Novapim e le prophylactic ho thibela ts'oaetso kamora ts'ebetso ea ho buoa: hora e le 1 pele ho ts'ebetso ea opereishene, hlahisa 2 g ea moriana, mme tharollo ea Metronidazole (500 mg).

Litekanyetso li beoa ka bomong ho latela botebo ba bothata ba kliniki kapa ho latela melao ea litlhare e khothalletsoang.

Litla-morao tsa Novapima

Tlolo ea litekanyetso kapa melao ea tsamaiso e baka likarabelo tse sa rateheng:

1. Sistimi ya mmele ya mmele: matshwao a eketsehang a hypersensitivity. Khafetsa - anaphylaxis, nts'etsopele ea makala a angioedema.
2. Mokhoa oa ka mpeng: ho nyekeloa le pelo le ho hlatsa, nts'etsopele ea li-candidiasis tsa mucous membrous ea cavity ea molomo, lets'ollo. Haholo-holo - ponahalo ea pseudomembranous colitis, ho sokela, ho sokolla pono ea tatso.
3. Tsamaiso ea methapo e bohareng: ho opeloa ke hlooho le ho tsekela, likhathatso tsa boroko, ho feto-fetoha hoa kelello. Khafetsa - nts'etsopele ea encephalopathy, ho akheha. Ka seoelo - ponahalo ea hallucinations, komisi, stupor.
4. Tšoaetso: Kholiso ea superinfection, vaginitis, vagidi candidiasis.
5. Ts'ebetso ea pelo le methapo: ponahalo ea tachycardia, bohloko mokokotlong oa pelo, edema ea potoloho.
6. Sistimi ea Lymphatic: thrombocytopenia, anemia, mofuta oa nakoana leukopenia, eosinophilia.
7. Sistimi ea ho hlasimoloha: khohlela e omeletseng, ho hema hanyane, 'metso o bohloko ha o ntse o koenya.
8. Litho tsa urinary: ka seoelo - nts'etsopele ea ho se sebetse hantle ha masapo.

Matšoao a mang a ka hlahang ha a ntse a nka Novapim: hemolytic mofuta anemia, ts'ebetso e sa tloaelehang ea sebete, ponahalo ea cholestasis, nephropathy e nang le chefo.

Ho ka tsosa keketseho ea sekhahla sa karabelo ea mofuta oa psychomotor, mabapi le seo ho khothalletsoang ho hana ho khanna koloi le ho sebetsa ka mekhoa e rarahaneng.

Bongata ba Novapim

E iponahatsa ka keketseho ea boholo ba matšoao a lehlakoreng. Phekolo ea overdose e na le matšoao. Ka nts'etsopele ea karabelo ea anaphylactic, tsamaiso ea hang-hang ea adrenaline e hlokahala. Ka tekanyetso e phahameng ea lithibela-mafu tse maling (bakeng sa ho felisoa ha eona kapele 'meleng), ho hlokahala peritoneal dialysis.

Ho sebelisana le lithethefatsi tse ling

Tharollo e lumellanang ea antibacterial le tharollo e joalo: 0,9% sodium chloride, tharollo ea tsoekere ea 10%, tharollo ea Ringer.

Ha e khothalletsoe ho nkuoa ka nako e le 'ngoe le Gentamicin Sulfate, Vancomycin, Metronidazole.

Ts'ebeliso e tšoanang ea Novapim e nang le aminoglycosides le diuretics ha e kenyelletsoe ka thoko. Motsoako ona o lebisa ho nts'etsopele ea phello ea nephrotic.

Joala le lino tse nang le joala ha li lumelloe ka thata nakong ea phekolo ea meriana e thibelang likokoana-hloko.

Meriana e nang le ts'ebetso e ts'oanang ea ts'ebetso: Abipim, Maxicef, Piccef, Focepim, Cefuroxime, Cefi.

Litlhahlobo mabapi le Novapima

Marina ea lilemo li 35, Vorkuta: “Ena ke lithibela-mafu tse thibelang matšoao a tšoaetso ka potlako. Empa o na le bothata bo boholo - liente li bohloko haholo. U ka kenella ka Lidocaine feela. Leha ho le joalo, sena ke sesebelisoa se sebetsang, ebile se theko e tlase. "

Ksenia, ea lilemo li 41, Perm: “Liente tsa Novapim li ne li laetsoe ke ngaka bakeng sa kalafo ea mathopa sefahlehong le 'meleng, hobane Ke ile ka utloa bohloko ka lilemo tse ngata, empa ha ho letho le ileng la nthusa. Koetliso ea kalafo ea lithibela-mafu e nkile matsatsi a 10, liente li le bohloko, empa li mamelleha ka lidocaine. Ho se ho fetile lilemo tse 1.5 ka mor'a kalafo, empa ho fihlela joale ha ho sa tsoa taba. ”

Eugene ea lilemo li 38, Dnipro o re: “Mor'abo r This ona o ile a nka moriana o thibelang likokoana-hloko hore a phekole lefu le fokolisang lefu la nkoe. Ka beke, tsohle li ile, matsatsi a mang a mararo a ile a etsa liente ho thibela ts'oaetso. Empa moriana oa hae o ile oa baka matšoao a lehlakoreng: hangata hlooho ea hae e ne e utloa bohloko 'me ka linako tse ling e ne e mo etsa hore a nyekane. Leha ho le joalo, meriana e thibelang likokoana-hloko e ntle, e theko e tlaase ebile e thusa ka potlako. ”

Litaelo tsa ho sebelisa Novapim

Vial e le 'ngoe e na le cefepime 1000 mg (e le motsoako o sa senyeheng oa cefepime hydrochloride le L-arginine).

Ts'oaetso e bakoang ke microflora e hlokoang ke lithethefatsi: mokhoa oa ho hema, ho kenyeletsa pneumonia, bronchitis, letlalo le matsoele a tšoaetsanoang, tšoaetso ea mpa ea mpa, ho kenyelletsa le peritonitis le tšoaetso ea phepelo ea lefu la pelo, gynecological, septicemia. Phekolo ea Empirical ea bakuli ba nang le feberu ea neutropenic. Thibelo ea mathata a ka mor'a ts'ebetso ho ts'ebetso ea mpa ea mpa.

Pneumonia Tšoaetso ea pampitšana ea urinary, ho kenyeletsa pyelonephritis. Tšoaetso ea letlalo le lisele tse ling. Septicemia, Empirical kalafo ea bakuli ba nang le feberu ea neutropenic. Meningitis ea baktheria.

Tekanyetso le tsamaiso

Pele o sebelisa moriana, tlhahlobo ea letlalo bakeng sa mamello e lokela ho etsoa.

Tekanyetso e tloaelehileng ea batho ba baholo ke 1 g. Lithethefatsi li fanoa kahare kapa ka methapo ka nako ea 12:00. Nako e tloaelehileng ea kalafo ke matsatsi a 7-10, ts'oaetso e matla e ka hloka kalafo ea nako e telele.

Tekanyetso le tsela ea tsamaiso li fapana ho ea ka kutloisiso ea likokoana-hloko, botebo ba ts'oaetso, le boemo bo sebetsang ba liphio tsa mokuli.

Bakeng sa thibelo ea tšoaetso nakong ea ts'ebetso ea ho buoa.

Metsotso e 60 pele ho ts'ebetso ea ho buoa, batho ba baholo ba lokela ho fana ka moriana ona oa meriana ka metsotso e 30. Kamora ho phethoa, 500 mg ea metronidazole e tsamaisoa ka matla. Litharollo tsa Metronidazole ha lia lokela ho tsamaisoa ka nako e le ngoe le Novapim. Sisteme ea infusion e lokela ho tlosoa pele ho tsamaiso ea metronidazole.

Nakong ea ts'ebetso ea nako e telele (ho feta 12:00) ts'ebetso ea ts'ebetso ea ts'ebetso ea 12:00 kamora tekanyetso ea pele, ho buelloa ho pheta-pheta ka tekanyetso e lekanang ea Novapim ka tsamaiso e latelang ea metronidazole.

Ts'ebetso ea mokokotlo e sa sebetseng. Bakeng sa bakuli ba nang le bothata ba ho sebetsa ha renal (tumello ea creatinine e ka tlase ho 30 ml / min), lethal dose la Novapim le tlameha ho fetoloa.

Ka hemodialysis ka hora ea boraro, hoo e ka bang karolo ea mashome a robeli a metso e robeli e tsoa 'meleng. Kamora ho phetheloa ha karolo ka 'ngoe ea dialysis, ho hlokahala hore ho hlahisoe lethal dose le phetoang, e leng tekanyetso ea pele.Ka "amitrate" e sebetsang kamehla ea "amitrate", moriana o ka sebelisoa litekanyetso tse tloaelehileng tsa 500 mg, 1 kapa 2 g, ho latela boteng ba ts'oaetso nako le nako ea lihora tse 48.

Bakeng sa bana likhoeling tse 1-2, moriana o lokela ho laeloa feela ka mabaka a bophelo. Boemo ba bana ba boima ba ho fihlela ho 40 kg ba fumanang kalafo le Novapim bo lokela ho lula bo beiloe leihlo.

Bakeng sa bana ba nang le bothata ba ho sebetsa ha renal, ho fokotsa tekanyetso kapa ho eketseha ha karohano lipakeng tsa tekanyetso.

Bana ba lilemo li 1 ho isa ho likhoeli tse peli. Novapim e lokela ho fuoa feela mabaka a bophelo bo botle 30 mg / kg boima ba mmele ka mong le e 12 kapa 8:00, ho latela boholo ba ts'oaetso.

Bana ba tsoang likhoeli tse peli. Tekanyo e phahameng ea bana ha ea lokela ho feta tekanyetso e khothalletsoang ho batho ba baholo. Tekanyetso e khothalletsoang bakeng sa bana ba boima ba ho fihlela ho 40 kg ho ts'oaetso ea ts'oaetso ea pampiri e rarahaneng kapa e sa rarahanang (ho kenyeletsa le pyelonephritis), ts'oaetso e sa rarahanang ea letlalo, pneumonia, hape le maemong a kalafo e matla ea febrile neutropenia ke 50 mg / kg ka hora e 'ngoe le e ngoe ka 12:00. neutropenia le bacterial meningitis - ka mor'a 8:00). Nako e tloaelehileng ea kalafo ke matsatsi a 7-10, ts'oaetso e matla e ka hloka kalafo e telele.

Bakeng sa bana ba nang le boima ba 'mele ba 40 kg kapa ho feta, Novapim e lokela ho beoa ka tsela e ts'oanang le ea batho ba baholo.

Kenyelletso ea moriana. Novapim e ka tsamaisoa kahare kapa ka ente e kenelletseng ka har'a mesifa e meholo (mohlala, karolong e ka holimo ea mokokotlo oa mokokotlo oa gluteus glusus gluteus).

Kenyelletso. Mokhoa o kenelletseng oa tsamaiso o khethoa ho bakuli ba nang le ts'oaetso e matla kapa e behang bophelo kotsing.

Ka tsamaiso ea methapo, Novapim e lokela ho qhibiliha ka metsing a sa hlapolloang bakeng sa ente, tharollo ea 5% ea glucose bakeng sa ente kapa 0.9% sodium chloride. Kena butle-butle kahare bakeng sa metsotso e 3-5 kapa ka tsamaiso ea methapo.

Ente ea methapo. Novapim e ka qhibiliha ka metsing a sa hlapolloang bakeng sa ente,

Tharollo ea chloride ea 0,9% ea sodium chloride, ente ea 5% ea tsoekere, metsi a bacteriostatic bakeng sa ente e nang le joala ea paraben kapa ea benzyl, 0.5% kapa 1% ea lidocaine hydrochloride.

Joalo ka lithethefatsi tse ling tse sebelisoang botsoali, tharollo ea lithethefatsi pele ho tsamaiso e lokela ho hlahlojoa hore na ho na le litšila tse sa sebetseng.

Ho khetholla pathogen ea likokoana-hloko (microorganism pathogen (pathogens)) le ho tseba hore na ho na le sensitivity ho cefepime, ho lokela ho etsoa lithuto tse nepahetseng tsa likokoana-hloko. Novapim e ka sebelisoa e le monotherapy le pele ho ts'oaetso ea microorganism ea pathogen, kaha e na le bongata bo bongata ba ketso ea antibacterial khahlano le likokoana-hloko tse mpe tsa gram. Ho bakuli ba kotsing ea tšoaetso ea aerobic / anaerobic (ho kenyeletsoa Bacteroides fragilis), kalafo le Novapim hammoho le sethethefatsi se amang anaerobes li ka qala pele pathogen e tsebahala.

Litlamorao

Ho tsoa ho sesole sa mmele: hypersensitivity reaction, ho kenyelletsa anaphylaxis, anaphylactic shock, angioedema.

Karolong ea letlalo: makhopho a letlalo, erythema, ho hlohlona, ​​urticaria.

Ho tsoa ho kanalary canal: ho nyekeloa, ho hlatsa, candidiasis ea molomo oa molomo, lets'ollo, colitis (ho kenyeletsa pseudomembranous), ho sokela, bohloko ba ka mpeng, dyspepsia, thrush, phetoho.

Ho tsoa ts'ebetsong ea tšilo ea lijo: hepatitis, cholestatic jaundice.

Ho tloha ts'ebetsong ea methapo: ho tsekela, ho opeloa ke hlooho, ho tšoenyeha, ho hloka boroko, paresthesia, pherekano, asthenia, ho ts'oaroa / tlhaselo ea sethoathoa, myoclonia, encephalopathy, ho lahleheloa ke letsoalo, ho bona lipono, ho akheha, ho akheha.

Mathata a akaretsang le liphetoho sebakeng sa ente: feberu, ho ruruha, bohloko ba morao, asthenia, liphetoho sebakeng sa ente, ho kenyelletsa ho ruruha, phlebitis, bohloko.

Tšoaetso: candidiasis, vaginitis, ho hlohlona ka botšehali, lefu la pseudomembranous colitis, ho hlasimoloha ho hong.

Ho tsoa ts'ebetsong ea ho hema: khatello ea phefumoloho, ho khohlela, komello e bohloko, ho hema hanyane.

Ho tsoa ho tsamaiso ea pelo le pelo: tachycardia, vasodilation, bohloko bo ka pelong, edema ea potoloho.

Ho tsoa ts'ebetsong ea moroto: ho se sebetse hantle ha renal.

Karolong ea mali le tsamaiso ea methapo ea methapo: anemia, eosinophilia, leukopenia ea nakoana, neutropenia, agranulocytosis, thrombocytopenia.

Ntle le liphetoho tse boletsoeng kaholimo tse boletsoeng ka holimo, litlatsetso tse ka 'nang tsa hlaha tsa lithibela-mafu tsa cephalosporin ke litsobotsi tsa Stevens-Johnson, erythema multiforme, chefo e nang le chefo e thibelang methapo ea mali, ho tsoa mali, ho fokola ha mali, ho fokola ha mali, ho tsoa mali, ho senyeha ha ts'ebetso ea sebete.

Mokhoa oa ho reka Novapim ho YOD.ua?

U hloka Novapim? E hlophise hona mona! Ho boloka meriana e meng le e ngoe ho teng ho YOD.ua: o ka nka sethethefatsi sena kapa oa fana ka odara ea litlama-tlama litoropong tsa toropo ea hau ka theko e boletsoeng webosaeteng. Taelo e tla u emela k'hemisteng, eo u tla fumana tsebiso ka mokhoa oa SMS (monyetla oa lits'ebeletso tsa ho tsamaisa o tlameha ho hlalosoa ka litlhare tsa meriana tsa molekane).

Ho YOD.ua ho lula ho na le leseli ka ho fumaneha ha moriana metseng e mengata e meholo ea Ukraine: Kiev, Dnieper, Zaporozhye, Lviv, Odessa, Kharkov le megacities tse ling. Ho ba ho e 'ngoe ea tsona, o ka sebelisa meriana habonolo ka ho sebelisa webosaete ea YOD.ua, ka nako e loketseng,' me u li latele litlolong tsa bongaka kapa ho fana ka odara.

Tlhokomeliso: Ho odara le ho amohela meriana e fanoang, o tla hloka lengolo la ngaka.