Fervex ea batho ba baholo ntle le tsoekere

Fervex ea batho ba baholo ntle le tsoekere (Tlhokomelo ea batho ba baholo ntle le tsoekere)

Litšobotsi tsa mantlha tsa lik'hemik'hale tsa physico: phofo ea granular e bobebe,

Sebopeho. 1 sachet e kenyelletsa pheniramine maleate 25 mg, paracetamol 500 mg, ascorbic acid 200 mg,

likarolo tse ling: mannitol, anhydrous citric acid, povidone, trimagnium dicitrate anhydrous, aspartame (phetoho ea tsoekere), tatso ea tlhaho ea Antillean.

Sebopeho sa ho lokolloa ha moriana.

Phofo ea tharollo bakeng sa ts'ebeliso ea kahare.

Sehlopha sa Pharmacotherapeutic.

Li-analgesics le li-antipyretics. Khoutu ea PBX N02B E51.

Ketso ea lithethefatsi.

Motheo oa lithethefatsi Fervex ke motsoako oa lithethefatsi tse sebetsang le tse sireletsehileng tse sebetsang ho li-link tsa mantlha pathogenesis ea sefuba. Paracetamol e na le antipyretic le analgesic effect, ascorbic acid - e lekana le tlhoko ea 'mele ea vithamine C, e eketsehang ka sefuba, pheniramine maleate - blocker of H1-histamine receptors, e fana ka phello e hlokang matla, e bonahatsoang ke ho fokotseha ha karabelo ea ho ruruha ea membrane ea mucous ea phepelo e phahameng ea phepelo (nasal , nko e tsamaeang ea fokotseha, ho thimola le ho heleha hoa hlaka). E lokiselitsoe e le tharollo e futhumetseng e nang le tatso e monate le monko, setlhare se fokotsa litlamorao tsa ho tahoa.

Mofumahali

Paracetamol kamora tsamaiso ea molomo e potlakile ebile e batla e kenelletse ka botlalo mohokelong oa tšilo ea lijo. Palo e phahameng ea paracetamol ho plasma e fihlelloa metsotso e 30-60 kamora ts'ebetso. Paracetamol e tšeloa matla ka ho fetisisa leseleng ho theha metsoako le glucuronic acid le sulfates. Ka tekanyo e nyane (ka tlase ho 4%) e hlophisoa ka oxidation ka sebopeho sa cysteine le mercaptopuric acid (ka ho nka karolo ha cytochrome P450).

E tšeloa ka har'a moroto, haholo-holo ka mokhoa oa metabolites. Hoo e ka bang 5% ea tekanyetso e nkuoeng ha e fetoloe.

Ho felisoa ha halofo ea bophelo ho etsa hore 2-2, 5 lihora. Metabolism ea paracetamol ho bakuli ba nang le lefu la sebete ha e fetohe.

Ascorbic acid (vithamine C) e kenella habonolo ka har'a tšilo ea lijo. Kamora ho monya, e potoloha ka plasma mme e teba ka har'a litšoelesa tsa endocrine. E fumaneha ka bongata bo boholo ba mokokotlo oa cortical le bokong ba adrenal gland. Keketseho ea ascorbic acid ho leukocytes le liplatelete e phahame ho feta ho plasma ea mali. Ascorbic acid e na le motsoako o mong oa oxalic acid kapa metabolites e meng e qhibilihang ka metsing, 'me e fokotsoa ka mokhoa o itseng ke liphio ka mokhoa o sa fetoheng. Catabolism ea ascorbic acid ke 2, 2-4, 1% ea phepelo ea eona eohle ea 'mele, eo ka eona e hakanyetsoang ho 1500 mg. Ho lumeloa hore phepelo ena ea 'mele e lekane bakeng sa 1-1, likhoeli tse 5 ka lebaka la khaello ea vithamine C lijong. Urinary excretion e qala kamora ho lula ho setsi sa depo ka ho feta 1500 mg. Ho bakuli ba nang le mehloli e fokotsehileng, vithamine C e ka 'na ea se ke ea hlaha ka har'a moroto leha e fanoa ka bongata bo boholo kahare kapa ka motsoali. Bophelo ba halofo ea ascorbic acid ke matsatsi a 12, 8 ho isa ho a 29, matsatsi a 5.

Pheniramine maleate e nkuoa hantle ho tsoa ho kanalary canal mme e kenella habonolo linthongng. Bophelo ba halofo ea plasma ke 1-1, lihora tse 5, bo tsoa ho 'mele haholo ke liphio.

Matšoao a ho sebelisoa.

Phekolo ea matšoao a sefuba, makhopho a allergic, makhopho, rhinopharyngitis, a bonahatsoang ke lets'ollo, hlooho, nko e phallang, ho thothomela le mala.

Mokhoa oa ts'ebeliso le tekanyetso.

Kahare, ho batho ba baholo le bana ba ka holimo ho lilemo tse 15, moriana o fuoa pakete e le 'ngoe makhetlo a 2 ka letsatsi. Likateng tsa mokotla li qhibilihile ka khalase ea metsi a batang kapa a futhumetseng. Bakuli ba nang le matšoao a sefuba ba lokela ho nka tharollo e futhumetseng. Tekanyetso ea pele e lokela ho etsoa kapele ka mor'a ho qala ha matšoao a pele a lefu lena. Tharollo e nkuoa hang kamora ho itokisa. Nako e pakeng tsa tekanyetso e lokela ho ba bonyane lihora tse 4.

Nako ea kalafo ha e sa feta matsatsi a 3.

Litla-morao.

Ho otsela, molomo o omileng, ho sitisoa ha bolulo, ho bolokoa ka urine, ho sokela, ho se leka-lekane le mohopolo, ho se tsotelle, haholoholo ho batho ba tsofetseng, hoa khoneha.

Khafetsa, litla-morao tse kulang (rash, urticaria).

Ka seoelo - thrombocytopenia, anemia, agranulocytosis, renal colic.

Meeli le li-contraindication ts'ebelisong ea lithethefatsi.

Hypersensitivity ho likarolo tsa moriana,

ho se sebetse hantle ha sebete le liphio,

tloaelo ea ho ruruha,

Prostate adenoma,

ka tlase ho lilemo tse 15

phenylketonuria (kaha lithethefatsi li kenyelletsa aspartame),

Ho eketsa tekanyetso e lumellehang ea lithethefatsi (overdose).

Haeba ho na le lithethefatsi tse ngata, litlamorao tsa lithethefatsi li ka bakoa ke: pheniramine le paracetamol, e bonahatsoang ke ho ts'oaroa ha kelello, ho akheha ha kelello, mokhathala. Hoa tsebahala hore ho nka paracetamol ka tekanyetso ea tse fetang 4 g ka letsatsi (ho batho ba baholo) ho ka ama sebete ho senya sebete mme sa baka hepatonecrosis.

Matšoao a botaoa (ho nyekeloa, ho hlatsa, ho ipolaisa tlala, bohloko ba ka mpeng, ho fufuleloa ho feteletseng) hangata ho hlaha ka lihora tse 24 tsa pele.

Phekolo: ho kena sepetlele, ho hlaseloa ka mpeng, N-asethylcysteine, e sebelisoang ka methapo kapa ka molomo, methionine, pontšo ea kalafo, e sebelisoang bakeng sa lihora tse 10 tsa pele e le motsoako oa paracetamol.

Likarolo tsa tšebeliso.

Sebelisa ka hloko ho bakuli ba nang le lefu la tsoekere.

Joala bo ntlafatsa matla a ho susumetsa a pheniramine maleate, hepatotoxicity ea paracetamol.

Lithethefatsi li ka baka ho otsela, e leng se etsang hore ho se sireletsehe ho khanna makoloi le ho sebetsa ka mekhoa.

Ha ho na datha mabapi le litlamorao tse mpe tsa lithethefatsi ho ima le ho anyesa, leha ho le joalo, moriana o lokela ho beoa nakong tsena ka hloko e kholo, ho nahanela kotsi le papiso.

Ascorbic acid e ka fetola liphetho tsa liteko tsa laboratori (tsoekere, bilirubin ea mali, ts'ebetso ea transaminase).

Ho thibela overdose, litokisetso tsohle tse nang le paracetamol li lokela ho hlakisoa le ho behelloa ka thoko.

Bakeng sa bakuli ba nang le bothata ba ho hlaphoheloa ha renal bo nang le tumello ea creatinine

Foromo ea boholo:

Mokotla o mong le o mong o na le:
ntho e sebetsang: paracetamol - 0,500 g, ascorbic acid - 0,200 g, maleir ea pheniramine - 0,025 g.
baamohelang: mannitol 3.515 g, citric acid 0,050 g, povidone KZO 0.010 g, magnesium citrate 0,400 g, aspartame 0,050 g, tatso ea lemone-rum * 0200 g.

Phofo ke beige e bobebe. Li-blotches tse sootho lia lumelloa.

Melemo ea pharmacological

Mofumahali
Fervex ® ke litokisetso tse kopaneng tse nang le paracetamol, pheniramine le ascorbic acid. Paracetamol ke analgesic e seng ya narcotic e thibelang cycloo oxygenase, haholo ts'ebetsong ea methapo e bohareng, e sebetsanang le litsi tsa bohloko le thermoregulation, mme e na le phello ea analgesic le antipyretic.
Pheniramine - H blocker₁- Li-receptor tsa "histamine", li fokotsa rhinorrhea le lacrimation, li tlosa makhopho a sefahleho, ho ruruha le hyperemia ea mucous membrane ea mucous ea nasal, nasopharynx le sinanas. Ascorbic acid e ameha ho tsamaisong ea lits'ebetso tsa redox, metabolism ea carbohydrate, coagulation ea mali, ho nchafatsoa ha lisele, ka har'a motsoako oa lihormone tsa steroid, ho fokotsa boteng ba vascular, ho fokotsa tlhokahalo ea livithamini tsa B₁, Ho₂, A, E, folic acid, pantothenic acid. E ntlafatsa mamello ea paracetamol mme e lelefatsa phello ea eona (e amanang le katoloso ea T½).

Mofumahali
Paracetamol
Kamora ho tsamaisoa ka molomo, e kenella ka potlako ho tsoa mokokotlong oa mpa. Palo e phahameng ea lithethefatsi ho plasma e fihlella metsotso e 10-60 kamora ts'ebetso. E ajoa ka potlako likarolong tsohle tsa 'mele, e kenella ka har'a mokoallo oa mali le bokong. Puisano le liprotheine tsa plasma ha e na thuso ebile ha e na boleng ba kalafo, empa e eketseha ka tekanyetso e ntseng e eketseha.
Metabolism e hlaha sebeteng, 80% ea lethal dose e nkoang e kenella ka har'a motsoako o nang le glucuronic acid le sulfates ho etsa metabolites e sa sebetseng, 17% e kenella ka hydroxylation le ho theha li-metabolites tse 8 tse sebetsang, tse kopaneng le glutathione ho theha metabolites e seng e sa sebetse. E 'ngoe ea li-katiba tsa metabolic tsa hydroxylated e bonts'a phello ea hepatotoxic. Metabolite ena ha e nke lehlakore ka ho kopana le glutathione, leha ho le joalo, e ka bokellana 'me haeba ho na le overdose ea paracetamol (150 mg ea paracetamol / kg kapa 10 g ea paracetamol ka molomo) e baka hepatocyte necrosis. E epolloa ke liphio ka mokhoa oa metabolites, haholo-holo ka mokhoa oa li-conjugates. Ka sebopeho se sa fetoloang, ka tlase ho 5% ea lethal dose e nkuoeng e supiloe. Ho felisoa ha halofo ea bophelo ho etsa lihora tse 1 ho isa ho tse tharo.
Feniramine:
E kenngoa hantle ka har'a tšilo ea lijo. Bophelo ba halofo e tsoang plasma ea mali bo tsoa ho hora e le 'ngoe le halofo. E tšeloa haholo-holo ka liphio.
Ascorbic asiti:
E kenngoa hantle ka har'a tšilo ea lijo. Nako ea ho theha kalafo e phahameng ka ho fetisisa ea kalafo (TCmax) kamora ho tsamaisoa ka molomo ke lihora tse 4. E tšelisoa haholo-holo ka har'a sebete. E pepesoa ke liphio, ka mala, ka mofufutso, e sa fetoheng le ka mokhoa oa metabolites.

* Sebopeho se khahlisang: maltodextrin, gum ea acacia, α-pinene, ß-pinene, limonene, γ-terpinene, linaloal, methapo, α-terpineol, geranial, dextrose, silicon dioxide Е551, butylhydroxyanisole.

Matšoao a ho sebelisoa

E sebelisoa bakeng sa tšoaetso ea phefumoloho e matla, tšoaetso ea vaerase e matla haholo, rhinopharyngitis ho kokobetsa matšoao a latelang:

rhinorrhea, khatello ea ka mpeng,
hlooho e bohloko
feberu
lacrimation
ho thimola.

Contraindication

Hypersensitivity ho paracetamol, ascorbic acid, pheniramine kapa motsoako ofe kapa ofe oa lithethefatsi.
Manonyeletso a ho ruruha le ho ruruha ha lisele tsa mpa ea ka mpeng.
Ho hloleha ha sebete.
Angle-shutter glaucoma.
Ho boloka urinary ho amanang le mafu a tšoelesa ea senya le mathata a ho ntša metsi.
Ts'oarelo ea mali a Portal.
Bokhoba ba tahi
Phenylketonuria.
Lilemo tsa bana (ho fihlela lilemo tse 15).
Bokhachane le pelehi (polokeho ha e so ithutoe).

Ka tlhokomelo

Ho hloleha ha setho sa botšehali, hyperbilirubinemia (Gilbert, Dubin-Johnson le Rotor syndromes), lefu la sebete la sethoathoa, hepatitis ea joala, botsofali.

Sebelisa nakong ea bokhachane le nakong ea ho anyesa

Lithuto tse lekaneng le tse laoloang hantle tsa lithethefatsi Fervex ® ho basali ba baimana ha li e-so etsoe, ka hona ha ho khothalletsoe tšebeliso ea lithethefatsi sehlopheng sena sa bakuli.

Ha ho tsejoe hore na lintho tse sebelisoang tsa moriana li fetela lebeseng la matsoele. Moriana ha oa lokela ho sebelisoa ha o qeta ho nyekeloa.

Tekanyetso le tsamaiso

Ka hare - 1 sachet makhetlo a 2-3 ka letsatsi. Pele o sebelisoa, se kahare sa mokotla se tlameha ho qhaloa ka khalase (200 ml) ea metsi a futhumetseng. Nako e telele ea kalafo ke matsatsi a 5. Tekanyo e phahameng ea letsatsi le letsatsi ea paracetamol ke 4 g (lipakete tse 8 tsa moriana Fervex ®) o nang le boima ba 'mele bo fetang li-50 kg. Nako e pakeng tsa tekanyetso ea moriana e lokela ho ba bonyane lihora tse 4.
Bakeng sa bakuli ba nang le bothata ba ho ruruha ba mesifa (creatinine clearance ®.
Pheniramin e le karolo ea boitokiso Fervex ® e ntlafatsa phello ea methapo: li-morphine tse tsoang ho tsona, li-barbiturates, li-benzodiazepines le li-tranquilizer tse ling, li-antipsychotic (meprobamate, phenogiazine derivatives), li-antidepressants (amitriptyline, mirtazapine, mianserinort antih, antihyport, antihan₁-Blockers, baclofen, le ha e sa eke feela matla a ho qhekella, empa hape e eketsa menyetla ea litla-morao tsa lithethefatsi (ho boloka mokokotlo, molomo o omeletseng, ho sokela).
Hoa hlokahala ho ela hloko monyetla oa ho ntlafatsa litlamorao tse ka hare tsa atropine ha o sebelisoa hammoho le lintho tse ling tse nang le thepa ea anticholinergic (li-antihistamine tse ling, li-antidepressants tsa sehlopha sa sehlopha sa lithethefatsi, lithethefatsi tsa phenoteazine, lithethefatsi tsa m-anticholinergic, litropine-like antispasmodic drug, disopyramide).
Ha o sebelisa lithethefatsi, hammoho le li-macrosomal oxidation inducers: barbiturates, tridclic antidepressants, anticonvulsants (phenytoin), flumecinol, phenylbutazone, rifampicin le ethanol, kotsi ea hepatotoxicity e eketseha haholo (ka lebaka la karolo ea paracetamol).
Li-glucocorticosteroids tse nang le tšebeliso ea nako e tšoanang li eketsa kotsi ea ho ba le glaucoma.
Ho amoheloa hammoho le li-salicylates ho eketsa kotsi ea nephrotoxicity.
Ka tšebeliso e tšoanang le chloramphenicol (chloramphenicol), chefo ea morao e eketseha.
Paracetamol e fumanehang ka har'a moriana e ntlafatsa litlamorao tsa li-anticoagulants tse sa tobang mme e fokotsa ts'ebetso ea lithethefatsi tsa uricosuric.

Litaelo tse khethehileng

Setlhare ha se na tsoekere ebile se ka sebelisoa ke bakuli ba nang le lefu la tsoekere.
Fervex ® ha ea lokela ho sebelisoa ka nako e tšoanang le meriana e meng e nang le paracetamol. Bakeng sa ho qoba ho senya ts'ebetso ea sebete, paracetamol ha ea lokela ho kopanngoa le lino tse tahang, hape e lokela ho nkuoa ke batho ba tloaetseng ho noella joala bo sa feleng.
Kotsi ea ho ba le tšenyo ea sebete e eketseha ho bakuli ba nang le hepatosis ea joala.
Ha o fetisa tekanyetso e boletsoeng mme o sebelisoa ka nako e telele, ho itšetleha ka kelello ho moriana ho ka hlaha.
Bakeng sa ho qoba tšebeliso e feteletseng ea paracetamol, o lokela ho etsa bonnete ba hore tekanyetso ea letsatsi le letsatsi ea paracetamol e fumanehang ka litlhare tsohle tse nkuoeng ke mokuli ha e fetele ho 4 g.

Tšusumetso ho bokhoni ba ho khanna makoloi le mekhoa

Ha ho fanoa ka monyetla oa ho ba le litlamorao tse sa rateheng tse kang ho otsela le ho tsekela, ho khothaletsoa ho hana ho khanna le ho sebetsa ka nako ea kalafo ka moriana.

Moetsi

Moqapi, sephutheloana (sephutheloana sa mantlha), sephutheloana (sephutheloana / sekontiri se phahameng), se fana ka taolo ea boleng
UPSASAS, Fora
979 Avenue de Pyrenees, 47520 Le Passage, France UPSASAS, France
979 avenue des Pyrenees, 47520 Le Passage, Fora

Likopo tsa bareki li lokela ho romelloa ho:
Bristol-Myers squibb LLC, Russia 105064, Moscow, ul. Zemlyanoy Val, 9

Setheo sa molao seo lengolo la sona la ngoliso le fanoeng
UPSASAS, Fora
3, ryu Joseph Monnier, 92500 Rueil-Malmaison, France UPSASAS, France
3, rue Joseph Monier, 92500 Rueil Malmaison, France

Sebopeho sa moriana

Lintho tse sebetsang: pheniramine maleate, paracetamol, ascorbic acid (vithamine C)

Sachet e le 1 e na le pheniramine maleate 25 mg, paracetamol 500 mg, ascorbic acid (vithamini C) 200 mg

Baeti: mannitol (E 421), citric acid, povidone, trimagnium dicitrate anhydrous, aspartame (E 951), tatso ea antillean.

Sehlopha sa mahlale

Li-analgesics le li-antipyretics. Khoutu ea PBX N02B E51.

Litlamorao tsa lithethefatsi ka lebaka la likarolo tsa sehlahisoa:

Pheniramine Maleate - H blocker ₁ -Histamine receptors, e fana ka phello e nyahamisang, e bonahatsoang ke ho fokotseha ha karabelo ea ho ruruha ea litho tsa mucous tsa phepelo e phahameng ea ho hema (ho phefumoloha ha nko hoa ntlafala, nko e otlang, ho thothomela le ho fokotseha ha leqhubu)
paracetamol e na le antipyretic le analgesic athari,
ascorbic acid e tlatsa tlhoko ea mmele ea vithamine C, e hola le sefuba.

Paracetamol kamora ho tsamaisoa ka molomo, e potlakile ebile e batla e kenelle ka botlalo mokhoeng oa ho silila. Palo e phahameng ea paracetamol ka plasma ea mali e fihlelloa metsotso e 30-60 kamora ho tsamaisoa. Paracetamol e tšeloa matla ka har'a sebete ho theha metsoako le glucuronic acid le sulfates.

E tšeloa ka har'a moroto, haholo-holo ka mokhoa oa metabolites. 90% ea lethal dose e nkuoeng e supuoa ke liphio nakong ea lihora tse 24, haholoholo ka mokhoa oa conjugates le glucuronic acid (60-80%), li-sulfate conjugates (20-30%).

Ka sebopeho se sa fetoheng, hoo e ka bang 5% ea tekanyetso e nkuoeng e qotsitsoe. Ho felisoa ha halofo ea bophelo ke hoo e ka bang ka 2:00.

Feniramine maleate e kenelletseng hantle haholo ka har'a tšilo ea lijo. E tšeloa haholo-holo ka liphio.

Ascorbic asiti e kenelletseng hantle haholo ka har'a tšilo ea lijo. E pepisoa haholo ka moroto.

Phekolo ea matšoao a sefuba, makhopho a kulang, mafu a sefuba, rhinopharyngitis, a bonahatsoa ke feberu, hlooho e opang, nko e kobehileng, ho thimola le ho hema.

Litšireletso tse loketseng tsa tšebeliso

Tabeng ea mocheso o phahameng oa 'mele kapa feberu ea nako e telele, e lulang matsatsi a 5 khahlano le tšebeliso ea moriana kapa ha ho hlaha matšoao a matla a phahameng ka ho fetesisa, o lokela ho etela ngaka ho fumana hore na ho na le monyetla oa ts'ebeliso ea moriana o mong hape.

Sebelisa ka hloko ho bakuli ba nang le lefu la tsoekere.

Joala bo ntlafatsa matla a ho susumetsa a pheniramine maleate, hepatotoxicity ea paracetamol.

Ascorbic acid e ka fetola liphetho tsa liteko tsa laboratori (tsoekere, bilirubin ea mali, ts'ebetso ea transaminase).

Kotsi ea ho itšetleha haholo ka kelello e bonahala ha e feta tekanyetso le ka kalafo ea nako e telele.

Ho thibela overdose, litokisetso tsohle tse nang le paracetamol li lokela ho hlahlojoa le ho behelloa ka thoko.

Bakeng sa batho ba baholo ba nang le boima ba 'mele bo fetang lik'hilograma tse 50, lethal dose ea paracetamol ha ea lokela ho feta 4 g ka letsatsi.

Tšebeliso ea lino tse tahang kapa tšebeliso ea methapo (haholo-holo barbiturates) e eketsa phello e matla ea pheniramine maleate, ka hona, lintho tsena li lokela ho qojoa nakong ea kalafo.

Bongata

E kopantsoe le pheniramine.

Mofuta o mongata oa pheniramine o ka baka ho tsitsipana (haholoholo baneng), ho akheha kelellong, com.

E kopantsoe le paracetamol.

Ho na le kotsi ea tahi ho batho ba baholo mme haholoholo baneng ba banyenyane (linyeoe tsa kalafo e fetelletseng ea kalafo le chefo ea phoso e atile haholo).

Mofuta o mongata oa paracetamol o ka bolaea.

Ho nyekeloa ke pelo, ho hlatsa, ho ipolaisa tlala, ho ruruha ho feteletseng, bohloko ba ka mpeng, hangata bo hlaha ka lihora tse 24 tse qalang.

Ho sebelisa tekanyetso e fetang 10 g ea paracetamol ka tekanyetso e le 'ngoe ho batho ba baholo le 150 mg / kg ea boima ba' mele ho lethal dose le le leng ho bana ho baka hepatic cytolysis, e ka lebisang ho necrosis e felletseng le e ke keng ea fetoloa, e lebisang ho haellang ha hepatocellular, metabolic acidosis, encephalopathy, eo, ho eona eona e ka lebisa ho komeng le lefung.

Ka nako e ts'oanang, ho na le boemo bo eketsehang ba li-transaminase tsa hepatic, lactate dehydrogenase le bilirubin khahlano le sekhahla sa boemo bo eketsehang ba prothrombin, bo ka hlahang lihora tse 12-48 kamora ts'ebeliso.

sepetlele kapele
qeto ea boemo ba pele ba paracetamol ho plasma ea mali
ho tlosoa hang-hang ha moriana o sebelisitsoeng ka sefuba,
Phekolo e tloaelehileng ea overdose e kenyelletsa ts'ebeliso ea litlhare tsa N-acetylcysteine ka molomo kapa ka molomo. Motsoakoana ona o lokela ho sebelisoa kapele kamoo ho ka khonehang, haholo-holo ka 10:00 kamora ho sebelisa overdose.
methionine e le pontšo ea kalafo.

Litlamorao

Ho tsoa ho hematopoietic le lymphatic system: anemia, sulfhemoglobinemia le methemoglobinemia (cyanosis, ho haella ha moea, bohloko ba pelo), hemolytic anemia thrombosis, hyperprothrombinemia, erythrocytopenia, thrombocytopenia, agranulocytosis, leukocytosis ea neutrophilic, leukopenia.

Ho tsoa ho sesole sa 'mele: anaphylaxis, anaphylactic shock, reaction hypersensitivity skin, ho kenyelletsa le pruritus, rashes letlalong le mucous membrous (hangata erythematous rash, urticaria), angioedema, erythema multiforme (syndrome ea Stevens-Johnson), chefo e nang le chefo ea epidermal necrolysis (lefu la Lyell).

Ho tsoa ts'ebetsong ea phefumoloho: bronchospasm ho bakuli ba amehang ka acetylsalicylic acid le li-NSAID tse ling.

Ho tsoa ts'ebetsong ea tšilo ea lijo: molomo o omileng, ho nyekeloa ke pelo, ho opeloa ke pelo, ho hlatsa, ho qhekelloa, bohloko ba epigastric, lets'ollo, ho senyeha ha ts'ebetso ea sebete, ho eketsa li-enzyme tsa sebete, hangata ntle le nts'etsopele ea jaundice, hepatonecrosis (phello e itšetlehileng ka tekanyetso).

Ho tsoa tsamaisong ea endocrine: hypoglycemia ho fihlela ho hypa-hypoglycemic coma.

Ho tsoa tsamaisong ea methapo: ka seoelo - hlooho e opang, ho tsekela, ho hlobaela ha boroko, ho akheha, ho akheha, ho bona lintho ka tsela e sa tloaelehang, ho tšoha, ho thothomela, maemong a mang - komello, ho putlama, dyskinesia, liphetoho tsa boits'oaro, ho sitisoa ho hoholo, ho se leka-lekane le mohopolo, ho sitisoa, haholoholo ho bakuli ba tsofetseng lilemo.

Ho tsoa ho tsamaiso ea pelo le pelo: maemong a ikhethileng - tachycardia, myocardial dystrophy (phello e itšetlehileng ka litekanyetso ka tšebeliso e telele), hypotension ea orthostatic.

Ka lehlakoreng la metabolism: metabolism ho se leka-lekane ha zinki, koporo.

Ho tsoa ts'ebetsong ea moroto: ho boloka urine le ho thatafalloa ho ntša metsi, aseptic pyuria, colic renal.

Ka lehlakoreng la letlalo: eczema

Ho tloha lehlakoreng la litho tsa pono: mahlo a omileng, mydriasis, bolulo bo senyehileng.

Ka tšebeliso ea nako e telele litekanyetsong tse kholo: ho senya lisebelisoa tsa menoana, kristallosia, sebopeho sa urate, cystine le / kapa oxalate calculi ka liphio le pampitšana ea urinate, tšenyo ea lisebelisoa tsa "pancreas" (hyperglycemia, glucosuria) le nts'etsopele ea lefu la tsoekere.

Ho sebelisana le lithethefatsi tse ling le mefuta e meng ea litšebelisano

Ka lebaka la ho ba teng ha pheniramine, ethanol e eketsa phello ea sedative ea H ₁ li-blockers, ka hona u lokela ho hana ho khanna likoloi kapa ho sebetsa ka mekhoa e meng. Nakong ea kalafo, tšebeliso ea lino tse tahang le tšebeliso ea litlhare tse nang le ethyl alcohol li lokela ho qojoa.

Mekhaako e lokela ho tsotelloa.

Ka lebaka la boteng ba pheniramine, lits'ebetso tse ling li ka baka khatello ea maikutlo tsamaisong ea methapo e kholo, joalo ka morphine derivatives (analgesics, compressants ea sefuba, le kalafo ea phetisetso), antipsychotic, barbiturates, benzodiazepines, anxiolytics, ntle le benzodiazepines (mohlala, meprobamate). , hypnotics, antidepressants tse matlafatsang (amitriptyline, doxepin, mianserin, mirtazapine, trimipramine), sedative N ₁ -Blockers, li-agent tsa antihypertgent tse bohareng, baclofen le thalidomide.

Ka lebaka la ho ba teng ha pheniramine, lithethefatsi tse nang le phello e kang atropine, joalo ka: imipramine antidepressants, atropine N e ngata ₁ li-blockers, li-anticholinergics, lithethefatsi tsa antiparkinsonia, atropine antispasmodics, disopramide, phenothiazine antipsychotic le clozapine li ka eketsa litlamorao tse sa rateheng tsa atropine, joalo ka ho bolokoa ha urineine, ho omella le molomo o omileng.

Teraflu: sebopeho, ts'ebetso ea meriana

Sesebelisoa se fumaneha ka mokhoa oa phofo, matlapa, litlolo le setlolo bakeng sa tsamaiso ea molomo. E na le paracetamol, pheniramine maleate le ascorbic acid.

Setlhare se na le sebopeho se leka-lekaneng, se etsang hore e se ke moriana o batang feela o sebetsang, empa hape se lumella hore se kopantsoe le lithethefatsi tse ling tse tsoang sehlopheng se le seng sa meriana.

Phofo ena e ikhethile, ka hona e tlosa matšoao ohle a feberu le sefuba se tloaelehileng, esita le lefu la tsoekere. Kahoo, ka thuso ea moriana, u ka tlosa ho khohlela, feberu, nko e bohloko le 'metso. Hape, lithethefatsi li matlafatsa sesole sa 'mele, ka tsela eo li potlakisa ho hlaphoheloa.

Khafetsa, Teraflu, joalo ka Fervex, e sebelisoa ntle le tsoekere bakeng sa mafu a kang:

hay fever
feberu
sinusitis
rhinopharyngitis,
sefuba
rhinitis
rhinorrhea
rhinosinusopathy le tse ling.

Mabapi le matšoao, moriana o na le vasoconstrictor (phenylephrine), immunostimulating (vithamini C), antipyretic, analgesic (paracetamol), hammoho le anti-allergenic effect (pheniramine).

Monyetla oa moriana ke hore e fapana ka sebopeho le matla a ho pepeseha, e lumellang bakuli ho khetha khetho e ntle ka ho fetisisa.

Empa khafetsa, ho khethoa ho fanoa ho li-powders tseo ho nooang lino tse chesang, hobane li sebetsa ebile li loketse ho li sebelisa.

Litaelo tsa tšebeliso ea lithethefatsi

Pakane e le 'ngoe ea phofo e nkuoa ka mor'a lihora tse' ne. Leha ho le joalo, nakong ea letsatsi u ka se noe ho feta mekotla e mene.

Pele o sebelisoa, sehlahisoa se tlameha ho qhibiliha ka khalase ea metsi a phehiloeng. Ho bohlokoa ho hlokomela hore batho ba nang le lefu la tsoekere ha baa lokela ho eketsa tsoekere ho noeng.

Moriana o lumelloa ho nooa ka nako efe kapa efe ea letsatsi. Leha ho le joalo, e na le phello e phahameng haeba u e noa pele u robala.

Ho noa sehlahisoa matsatsi a fetang a 5 a latellanang ho thibetsoe. Ntle le moo, ts'ebeliso ea eona e lumelloa feela ho tloha lilemong tsa leshome le metso e 'meli.

Ka lipontšo tse hlakileng tsa feberu kapa sefuba, o ka khetha pheko eseng feela ka botebo ba phello ea kalafo, empa hape le ho latsoa. 'Me boholo bo lekaneng ba paracetamol (325 mg) e na le phello e phahameng ea li-analgesic le antipyretic.

Ka mefuta e matla ea ts'oaetso ea vaerase e matla haholo, u ka sebelisa Teraflu Extra, e nang le tatso ea sinamone le apole. E le karolo ea mofuta ona oa sehlahisoa, ho na le tekanyetso e habeli ea ntho e sebetsang (650 mg). Sena se o lumella ho potlakela ho theola mocheso le ho fokotsa botebo ba matšoao a lefu lena.

Leha ho le joalo, ho sebelisa lithethefatsi ka mokhoa oa phofo ha ho bonolo kamehla, kaha batho ba bangata ba nang le lefu la tsoekere, ba nang le sefuba, ba ka ea mosebetsing.

Maemong ana, ba ka sebelisa matlapa a Teraflu.

Fervex: sebopeho, phello ea kalafo, litlamorao le li-contraindication

Fervex ke phofo ea granular e nang le 'mala o bobebe oa beige. Sachet e le 'ngoe e na le paracetamol (500 mg) pheniramine maleate (25 g) le Vitamin C (200 mg). Aspartame e sebelisoa e le sebaka sa tsoekere.

Motheo oa moriana ke motsoako oa lintho tse sebetsang tsa phekolo tse felisang matšoao a sefuba se tloaelehileng. Ka hona, kamora ho nka seno se chesang, mocheso oa fokotseha, bohloko bo ka 'metso le hlooho bo ea fokotseha, ho ruruha ho tlosoa mme nko e lerootho le lacrimation lia nyamela.

Matšoao a ts'ebeliso ea Fervex a tšoana le a Teraflu.

Mabapi le litla-morao, joale ka mor'a ho nka moriana, ho sokela, ho otsela, ho senyeha hoa mohopolo, ho ka ba le botsitso. Ho lula urinary, ho sitisoa ha bolulo, molomo o omileng le tsona lia khoneha, 'me bakuli ba tsofetseng ha ba tsotelle. Ka tlase khafetsa, mokuli a ka ba le mathata a ho ruruha (urticaria, rashes), ka linako tse ling a real colic, thrombocytopenia, agranulocytosis, le anemia ho lefu la tsoekere le lefu la tsoekere.

Lintho tse amanang le tšebeliso ea Fervex ke tsena:

tloaelo ea ho etsa metheo ea mali,
hypersensitivity ho likarolo tsa moriana,
angle-shutter glaucoma,
lilemo ho fihlela lilemo tse 15
bokhoba ba joala
Prostate adenoma,
phenylketonuria,
ho hlaphoheloa ha liphio le sebete.

Litaelo tsa ho sebelisoa

O ka noela li-sachets tse 2-3 ka letsatsi. Empa pele, litaba tsa sephutheloana li lokela ho qhibiliha ka khalase ea metsi a futhumetseng kapa a batang.

Litaelo tse se nang tsoekere tsa Fervex bakeng sa tšebeliso li re tekanyetso ea pele e molemo ho hlahisa kapele kamora matšoao a pele a lefu lena. Tharollo e lokela ho nooa hang kamora ho itokisa, 'me nako ea bolelele bo pakeng tsa litekanyetso li lokela ho ba bonyane lihora tse 4. Nako ea kalafo ha e sa feta matsatsi a mararo.

Haeba tekanyetso e fetisitsoe, paracetamol le feniarmin li ka ba le phello e chefo 'meleng, e bonahatsoang ke ho tsitsipana hoa letsoalo, ho tsitsinyeha le ho akheha.

Ho sebelisa tekanyetso e fetang tekano ho ka etsahala haeba tekanyetso ea paracetamol ho motho e moholo e feta ligrama tse 4, e ka bakang hepatonecrosis. Matšoao a botahoa a ka ba teng ka mora letsatsi ka mor'a ho nka Fervex. Phekolo e entsoe ka lavage ea ka mpeng le tsamaiso ea methapo ea methapo ea N-asethylcysteine, methionine le kalafo ea matšoao.

Litsenyehelo tsa Fervex ntle le tsoekere (li-pcs tse 8. Pakete e le 'ngoe) li tloha ho li-ruble tse 270 ho isa ho tse 600. Theko ea phofo ea Teraflu e ipapisitse le palo ea lipakete: li-4 likhomphutha. - ho tloha ho 200 p., li-pcs tse 10. - li-ruble tse 380.

Video e sehloohong sena e fana ka leseli le felletseng la ho phekola feberu ea lefu la tsoekere.