Thioctacid 600: litaelo tsa tšebeliso, lipontšo, litlhahlobo le li-analogues

Thioctacid BV: litaelo tsa tšebeliso le litlhahlobo

Lebitso la Latin: Thioctacid

Khoutu ea ATX: A16AX01

Motsoako o sebetsang: thioctic acid (thioctic acid)

Mohlahisi: GmbH MEDA Production (Jeremane)

Nchafatso ea litlhaloso le foto: 10.24.2018

Litheko makaleng a meriana: ho tloha ho li-ruble tse 1604.

Thioctacid BV ke lithethefatsi tsa metabolic tse nang le litlamorao tsa antioxidant.

Sokolla foromo le sebopeho

Thioctacid BV e fumaneha ka mokhoa oa matlapa a koahetsoeng ka koae ea filimi: botala bo botala-mosehla, li-oblong biconvex (li-pcs tse 30, 60 kapa 100. Ka libotlolong tsa khalase tse lefifi, botlolo e le 'ngoe ka lebokoseng la karete.

Letlapa le le leng le na le:

• ntho e sebetsang: thioctic (alpha-lipoic) acid - 0,6 g,
• likarolo tse thusang: magnesium stearate, hyprolose, hyprolose e nkiloeng ka tlase,
• sebopeho sa koaelo ea filimi: titanium dioxide, macrogol 6000, hypromellose, varnish ea aluminium e thehiloeng ho indigo carmine le dae quinoline e ntšo, talc.

Mofumahali

Thioctacid BV ke lithethefatsi tsa metabolic tse ntlafatsang li-trophic neurons, li na le hepatoprotective, hypocholesterolemic, hypoglycemic, le lipid-lowering liphello.

Sesebelisoa se sebetsang sa lithethefatsi ke thioctic acid, e leng 'meleng oa motho ebile ke antioxidant ea endo native. Ha e le coenzyme, e nka karolo phosphorylation ea oxidative ea pyruvic acid le alpha-keto acid. Mochine oa ts'ebetso oa thioctic acid o haufi le phello ea biochemical ea livithamini tsa B. E thusa ho sireletsa liseleng ho tsoa litlamong tse chefo tsa radicals tse sa fetoheng tse etsahalang lits'ebetsong tsa metabolic, 'me li sitisa metsoako ea chefo e tsoang' meleng. Ho eketsa boemo ba glutathione ea endo native antioxidant, ho baka ho fokotseha ho teba ha matšoao a polyneuropathy.

Matla a synergistic a thioctic acid le insulin ke keketseho ea ts'ebeliso ea tsoekere.

Mofumahali

Ho amoheloa ha thioctic acid ho tsoa lipakeng tsa gastrointestinal (GIT) ha e tsamaisoa ka molomo e etsahala kapele le ka botlalo. Ho nka sethethefatsi ka lijo ho ka fokotsa ho monya ha eona. C_max (mahloriso a mangata) plasma ea mali kamora ho nka tekanyetso e le 'ngoe e fumanoa kamora metsotso e 30 mme ke 0.004 mg / ml. Tekanyo e felletseng ea Thioctacid BV ke 20%.

Pele o kenella ho potoloha ha tsamaiso ea mali, thioctic acid e feta phello ea karolo ea pele e kenang ka har'a sebete. Mekhoa e kholo ea metabolism ea eona ke oxidation le conjugation.

T_1/2 (halofo ea bophelo) ke metsotso e 25.

Tlhahiso ea ntho e sebetsang ea Thioctacid BV le metabolites li etsoa ka liphio. Ka moroto, 80-90% ea lithethefatsi e hlobolisitsoe.

Litaelo tsa ho sebelisa Thioctacid BV: mokhoa le litekanyetso

Ho ea ka litaelo, Thioctacid BV 600 mg e nooa ka mpeng e se nang letho kahare, lihora tse 0.5 pele ho lijo tsa hoseng, e metsa e felletseng mme e nooa metsi a mangata.

Tekanyetso e khothalelitsoeng: 1 pc. Hang ka letsatsi.

Ha ho fanoa ka ts'ebeliso ea bongaka, bakeng sa kalafo ea mefuta e matla ea polyneuropathy, ts'ebetso ea pele ea tharollo ea thioctic acid bakeng sa tsamaiso ea methapo (Thioctacid 600 T) e khonahala ka nako ea matsatsi a 14 ho isa ho a 28, e lateloe ke phetisetso ea mokuli ho ea ts'ebelisong ea letsatsi le letsatsi ea lithethefatsi (Thioctacid BV).

Litlamorao

• ho tsoa ho ts'ilo ea lijo: hangata - ho nyekeloa pelo, hangata - ho hlatsa, bohloko ka mpeng le mala, lets'ollo, tlolo ea methapo ea maikutlo,
• ho tloha tsamaisong ea methapo: hangata - ho tsekela,
• karohano e bakoang ke ho hlaseloa ke lintho tse sa utloahaleng: ka seoelo - ho hlohlona, ​​lekhopho la letlalo, urticaria, ho thothomela ha anaphylactic,
• karolong ea 'mele ka kakaretso: ka seoelo - ho fokotseha ha tsoekere ea mali, ponahalo ea matšoao a hypoglycemia ka hlooho, pherekano, ho fufuleloa ho eketsehileng, le ho senyeha hoa mahlo.

Bongata

Matšoao: Khahlano le semelo sa tekanyetso e le 'ngoe ea 10-40 g ea thioctic acid, ho tahoa ho matla ho ka hlaha ka lipontšo tse kang ho ts'oaroa ka mokhoa o phollatsi, hypoglycemic coma, likhathatso tse matla tsa tekano ea acid-base, lactic acidosis, mathata a tsoang mali a mangata (ho kenyeletsa le lefu).

Phekolo: haeba ho belaelloa tekanyetso e fetang ea Thioctacid BV (tekanyetso e le 'ngoe bakeng sa batho ba baholo ho feta matlapa a 10, ngoana o feta 50 mg ka kilo e le' ngoe ea boima ba hae ba mmele), mokuli o hloka ho kenella sepetlele hanghang ka ho beoa kalafo ea matšoao. Haeba ho hlokahala, kalafo ea anticonvulsant e sebelisoa, mehato ea tšohanyetso e reretsoeng ho boloka mesebetsi ea litho tsa bohlokoa.

Litaelo tse khethehileng

Kaha ethanol ke sesosa sa kotsi bakeng sa nts'etsopele ea polyneuropathy mme e baka ho fokotseha hoa katleho ea kalafo ea Thioctacid BV, tšebeliso ea joala e hanyetsoa ka thata ho bakuli.

Phekolo ea lefu la tsoekere la polyneuropathy, mokuli o lokela ho theha maemo a netefatsang hore ho ba le tsoekere e ngata maling.

Contraindication

• bana le bacha ba ka tlase ho lilemo tse 18 (ha ho na tlhahiso-leseling ka tšebeliso ea lithethefatsi lilemong tsena),
• nako ea kemolo le ho nyekelo (ha ho na boiphihlelo bo lekaneng ka tšebeliso ea lithethefatsi),
• hypersensitivity ho thioctic acid kapa likarolo tse thusang tsa sethethefatsi.

Tekanyetso le tsamaiso

Matlapa a Thioctacid BV a nooa ka molomo, ha a hlafuna, empa a metsoa a felletse 'me a hlatsuoa ka metsi. Moriana o nooa ka mpeng e se nang letho, hoseng, metsotso e 30 pele ho lijo tsa hoseng.

Sekhahla sa letsatsi le letsatsi ke 600 mg (1 pilisi) hang.

Ho polyneuropathy e matla, kalafo e qala ka ho kenella ka hare ho moriana ka mokhoa oa tharollo (Thioctacid 600 T). Kamora libeke tse 2 ho isa ho tse peli tsa phekolo ka mofuta oa boroko oa thioctic acid, mokuli o fetisetsoa ho ho nka matlapa a Thioctacid BV.

Ho sebelisana le lithethefatsi

Asiti ea Thioctic (α-lipoic) e fokotsa ts'ebetso ea cosplatin mme e ka ntlafatsa phello ea li-hypoglycemic agents kapa insulin. Maemong a mang, hoa utloahala ho fokotsa tekanyetso ea lithethefatsi tsa hypoglycemic ho qoba nts'etsopele ea matšoao a hypoglycemia.

Tai ea Ethyl le metabolites tsa eona li fokotsa phello ea Thioctacid BV.

Tlhahlobo ho Thioctacide BV

Tlhahlobo ea Thioctacide BV hangata e ntle. Bakuli ba nang le lefu la tsoekere ba bontša ho fokotseha ha tsoekere ea mali le cholesterol, bophelo bo botle khahlano le semelo sa tšebeliso ea lithethefatsi ka nako e telele. Karolo ea lithethefatsi ke tokollo e potlakileng ea thioctic acid, e thusang ho potlakisa lits'ebetso tsa metabolic le ho tlosoa hoa mafura a tsoang 'meleng, phetoho ea lik'habohaedreite matla.

Tšusumetso e ntle ea kalafo e hlokomeleha ha u sebelisa moriana bakeng sa kalafo ea sebete, mafu a methapo le botenya. Ha ho bapisoa le li-analogues, bakuli ba bonts'a boemo bo tlase ba litlamorao tse sa batleheng.

Ho bakuli ba bang, ho sebelisa moriana ona ho ne ho se na phello e lebelletsoeng ea ho theola cholesterol kapa ho tlatsetsa ho nts'etsopele ea urticaria.

Matšoao a sebelisang Thioctacid 600

Matšoao a sebelisang Thioctacid 600 ke:

• lefu la tsoekere le joala le polyneuropathy,
• Hyperlipidemia,
• mafura a mafura,
• cirrhosis le lefu la sebete,
• botaoa (ho kenyelletsa le matsoai a boima ba tšepe, li-toadstools),
• kalafo le thibelo ea coronary atherosulinosis.

Litaelo tsa ho sebelisa Thioctacid 600, litekanyetso

Tekanyetso e tloaelehileng

Liente Thioctacid 600 li tsamaisoa ka / in (jet, drip). Matlapa a Thioctacid a 600 - litekanyetso tsa 600 mg / letsatsi bakeng sa lethalinyana le le leng (hoseng ka mpeng e se nang letho metsotso e 3040 pele ho lijo tsa hoseng), makhetlo a 200 mg makhetlo a 3 ka letsatsi ha a sebetse hantle.

E khethehileng

Mefuteng e matla ea polyneuropathy - iv butle (50 mg / min), 600 mg kapa iv drip, ka tharollo ea 0,9% NaCl hang ka letsatsi (maemong a boima, ho fihla ho 1200 mg e fanoa) bakeng sa libeke tsa 2-4. Kamora moo, ba fetohela kalafong ea molomo (baholo - 600-1200 mg / ka letsatsi, bacha - 200-600 mg / letsatsi) bakeng sa likhoeli tse 3. Ho / kenyelletsong ho khonahala ka thuso ea moetsi oa litlolo (nako ea tsamaiso - bonyane metsotso e 12).

Mokhoa oa kalafo o nang le thioctacid bakeng sa bakuli ba nang le lefu la tsoekere la polyneuropathy o thehiloe hantle mme o na le motheo o tiileng oa saense le o sebetsang. Phekolo e qala ka ho kenyelletsa thioctacide kahare ho lethal dose ea 600 mg bakeng sa libeke tse peli.

Ka kalafo e tšoanang ka lithethefatsi tse nang le matla le Thioctacid, litlhahiso tsa ngaka e eang ho tsona li lokela ho nkuoa ka hloko.

Likarolo tsa ts'ebeliso

Bakuli ba bangata ba tletleba ka nako e telele e nkang ho tsamaisa lithethefatsi Thioctacid 600 T ka mokhoa oa tharollo ea infusion e kenang. Leha ho le joalo, lingaka li khothaletsa mofuta ona oa moriana qalong ea kalafo ea lefu lena. E kenelletse ka botlalo mme e u fa monyetla oa ho kopitsa litekanyetso tse sebetsang hantle.

Ha u sebelisa lithethefatsi, motho o lokela ho hana ho khanna makoloi le ho sebetsa ka mekhoa e ka bang kotsi.

Haeba ho na le tlhoko ea taolo e tšoanang ea lithethefatsi tsena, u tla tlameha ho mamella nako e telele lipakeng tsa taolo ea bona ka lihora tse hlano ho isa ho tse tšeletseng.

Moriana o ka har'a ampoules ha o pepesehe khanya ho fihlela o sebelisoa ka kotloloho. Tharollo e felileng e sebelisoa lihora tse tšeletseng le ho sireletsoa ke bobebe.

Ho nwa joala ho ka fokotsa katleho ea moriana. Ka hona, ho khothalletsoa ho hana ho nka lino tse nang le lino tse tahang nakong ea kalafo le moriana.

Ka tlhokomeliso, kopanya le li-agents tse nang le tšepe, lisplatin, insulin le meriana ea lefu la tsoekere.

Mehatong ea pele ea kalafo, ho matlafatsoa ha maikutlo a sa thabiseng ka neuropathy, ho amanang le ts'ebetso ea ho khutlisetsa sebopeho sa fiber ea methapo.

Litla-morao le li-contraindication Thioctacid 600

Ka tsamaiso ea methapo e potlakileng ea Thioctacid 600 T, khatello ea kelello e kenang ka linako tse ling e ka eketseha 'me ho tšoaroa ho phefumolohang ho ka bonoa. Ha e le molao, litlolo tsena li itlhahela feela.

Nakong ea ts'ebeliso ea Thioctacid maemong a mang, boemo ba tsoekere maling bo ka fokotseha (ka lebaka la ntlafatso ea tšebeliso ea eona). Tabeng ena, hypoglycemia e ka hlaha, matšoao a mantlha ao e leng: ho tsekela, ho opeloa ke hlooho, ho ruruha ho feteletseng (hyperhidrosis) le likhathatso tsa pono.

Tlhahlobo ea thioctacide ka mokhoa oa liente e tlaleha maemo a ts'ohanyetso a tsamaiso ea methapo. Haeba litekanyetso li khothalelitsoe haholo, matšoao a tahi a ka hlaha, a hlalositsoeng ka tlase.

Bongata

Tekanyo e kholo ea tekanyetso kapa tšebeliso ea Thioctacid ka joala e ka baka matšoao a botaoa ka kakaretso.

Haeba ho na le bongoana bo feteletseng, ho nyekeloa le pelo, ho hlatsa le hlooho e ka hlaha. Kamora ho ts'oara ka phoso kapa ha o leka ho ipolaea ka tsamaiso ea molomo ea thioctic acid ka tekanyetso ea 10 g ho isa ho 40 g, hammoho le joala, ho tahoa ho matla ho boleloa, maemong a mang ho bile le phello e bolaeang.

Qalong feela, ho tahoa le lithethefatsi Thioctacid BV ho bontšoa ke khatello ea maikutlo le mathata a kelello. Ebe lactic acidosis le ho tsitsipano ea methapo e se e le teng. Ka tekanyo e kholo ea tekanyetso e lumelehang ea alpha-lipoic acid, hemolysis, hypokalemia, ho tsitsipana, ho hloleha ha litho tse ngata, rhabdomyolysis, DIC, le myelosuppression.

Haeba ho belaelloa bokhoba ba tahi ea lithethefatsi, ho khothalletsoa ho kena sepetlele hanghang le ts'ebeliso ea mehato ho latela melaoana e akaretsang ea chefo ea kotsi ka tšohanyetso (ho etsa mohlala, ho hlatsa, ho hlatsoa mpa, ho sebelisa mashala a ts'ebetso, jj., Pele ambulense e fihla).

Contraindication

• Hypersensitivity ho alpha-lipoic acid kapa ho likarolo tse ling tsa lithethefatsi.
• Lilemo tsa bana ho fihlela lilemo tse 15.
• Nako ea bokhachane le pelehi.

Analogs Thioctacid 600, lenane

Litšoantšo tse ka sehloohong tsa Thioctacid bakeng sa ntho e sebetsang li kenyelletsa lithethefatsi: Berlition 300, Oktolipen, Lipothioxon, Thiogamma, Lipamide, Tiolept, Thiolipon, Lipoic acid, Espa-Lipon le Neurolepone.

Har'a li-analogues, tse theko e phahameng ka ho fetisisa le tse sebetsang ke:

1. Kuvan Pills,
2. Capsules Curtain le Orfadin,
3. Homeopathic meriana Gastricumel,
4. Matlapa a betliloeng a bana ba Bifiform.

Bohlokoa - litaelo tsa ts'ebeliso ea Thioctacid 600, theko le litekanyetso ha li sebetse ho li-analogues 'me li ke ke tsa sebelisoa e le tataiso bakeng sa tšebeliso ea lithethefatsi tsa sebopeho se tšoanang. Litefiso tsohle tsa kalafo li lokela ho etsoa ke ngaka. Ha o khutlisa Thioctacid 600 ka analogue, ho bohlokoa ho fumana boeletsi ba setsebi, ho ka hlokahala hore u fetole mokhoa oa phekolo, litekanyetso, joalo-joalo u se ke oa inahanela!

Ho lefu la tsoekere, ho tlamehile ho nka thupelo ea Thioctacid 600 hang kapa habeli ka selemo. Haeba sethethefatsi sena se sa lokelang, se lokela ho nkeloa sebaka ke analog. Ho thata ho hana lithuto tsa mofuta ona.

Boholo ba bakuli ba sebelisang lithethefatsi ena ba hlokomela hore e sebetsa hantle ho loants'a lefu la tsoekere le ho senya ts'enyo ea methapo ea methapo ea kutlo. Tlhahlobo ea Thioctacid 600 e bonts'a ho fokotseha le hoholo ha matšoao a joalo ka bohloko bo lipheletsong tse tlase, ho se phomole phomolong, ho sithabela maikutlo le ho choachoasela ka tsela e tenang.

Lithethefatsi Thioctacid

Thioctic acid, e leng eona karolo ea mantlha e sebetsang ea moriana, e hlahisoa ke 'mele o phetseng hantle bakeng sa tšebetso e tloaelehileng ea lisele le ho thibela tšenyo ea lisele. Thioctacid e sebetsana le litšenyehelo tsa methapo ea sele le ho phallo ea mali e sa sebetseng hantleng ka lebaka la liphetoho mokhoeng oa marako a methapo ea mali, boteng ba li-plagi tsa atherosselotic.

Sebopeho le mofuta oa tokollo

Setlhare se fumaneha ka mokhoa oa litafole tsa tokollo tse potlakileng le tharollo ea infusion. Litlhaku tse kenyellelitsoeng mabitsong li etsa hore ho be bonolo ho tseba hore na li rekisoa ka foromo efe. Moriana o tšoauoa ka thepa e latelang:

Lebitso le sa Tšoaneleheng la Machabeng

thioctacid 600 t

Matlapa a koahetsoeng ka filimi

Tharollo ea entevenous ea ente

Thioctic (alpha lipoic) acid - 600 mg

Hyprolose e sa nkeloang tlase, magnesium stearate

Metsi a sterile, trometamol

Sebopeho sa khetla ea filimi

hypromellose, macrogol 6000, titanium dioxide, talc, varnish ea aluminium

Matlapa a koahetsoeng a botala bo bosehla bo nang le oblong biconvex

Yellowish e hlakileng e metsi

Bophahamo ba Package

Matlapa a 30 kapa 100

Li-ampoules tse 5 tsa 24 ml

Mali

Sesebelisoa se sebelisoa ho tloaela tšebetso ea metabolic liseleng. Thioctic acid ke antioxidant ea tlhaho e hlahisoang ke 'mele oa motho mme e bokelloa ke likhoele tsa methapo ho sireletsa lisele ho litlamorao tse mpe tsa lik'hemik'hale tse kotsi - li-radicals tsa mahala, tse hlahisoang ke metabolism. 'Meleng, ntho e bapala karolo ea coenzyme.

Ho ba teng ha thioctic asiti ka har'a mokelikeli oa metsoako ea methapo le sele ho eketsa palo ea glutathione, e ikarabellang bakeng sa ho bonahatsa matšoao a methapo. Phekolo e fokotsa khatello ea mali, e thusa ho fokotsa cholesterol hape e thibela nts'etsopele ea atherosulinosis ea methapo ea mali, ka tsela eo e ntlafatsa phallo ea mali. Bokhoni ba alpha-lipoic acid ho ntlafatsa ketso ea insulin e etsa hore e be karolo ea bohlokoa molemong oa ts'ebeliso ea tsoekere ho bakuli ba lefu la tsoekere.

Sebopeho, foromo ea tokollo le lebitso la thioctacid

Hajoale, thioctacid e fumaneha ka mefuta e 'meli ea litekanyetso:
1. Litafole tse lokolloang ka potlako bakeng sa tsamaiso ea molomo,
2. Tharollo bakeng sa tsamaiso ea methapo.

Matlapa a Thioctacid BV a sebelisoa hang ka letsatsi, 1 tab.ka mpeng e se nang letho ka metsotso e 20-30. pele ho lijo. Nako ea ho amoheloa e ka ba bonolo bakeng sa mokuli.

Tharollo ea infravenous infusion e bitsoa hantle Thioctacid 600T . Kahoo, litlhaku tse fapaneng tse kentsoeng lebitsong la sehlooho la moriana li etsa hore ho be bonolo ho utloisisa hore na ho latela mofuta ofe oa litekanyetso.

Joaloka motsoako o sebetsang, matlapa le ho tsepamisa mohopolo li na le thioctic acid (alpha lipoic). Tharollo ke letsoai la trometamol la thioctic acid, leo e leng sehlahisoa se sireletsehileng ka ho fetisisa ho fetisisa ebile se theko e phahameng haholo ho hlahiseng. Lintho tsa Ballast ha li eo. Tromethamol ka boeona e sebelisoa ho khutlisetsa tekanyo ea acid-base ea mali. Tharollo e na le 600 mg ea thioctic acid ho 1 ampoule (24 ml).

Joaloka likarolo tse thusang e na le metsi a sa hlapolloang bakeng sa ente le trometamol, ha e na glycols ea propylene, ethylenediamine, macrogol, jj. Matlapa a Thioctacid BV a na le bonyane ba li-excipients, ha li na lactose, starch, silicon, oli ea castor, jj., Hangata e eketsoa lithethefatsi tse theko e tlaase.

Matlapa a na le sebopeho sa oblong, sa biconvex mme a 'mala o mosehla o bosehla. E fumaneha ka har'a mekotla ea likotoana tse 30 le 100. Tharollo e hlakile, e pentiloe ka 'mala o mosehla. E fumaneha ka li-ampoules tsa 24 ml, tse pakiloeng ka har'a lipakete tsa 5 likhomphutha.

Thioctacid - boholo le litlamorao tsa kalafo

Ntho e sebetsang ea Thioctacid e kenella ho metabolism le matla a entsoeng ho mitochondria. Mitochondria ke meaho ea lisele e fanang ka sebopeho sa matla a bokahohleng a ATP (adenosine triphosphoric acid) ho tloha mafura le lik'habohaedreite. ATP e sebelisoa ke lisele tsohle e le mohloli oa matla. Ho utloisisa karolo ea molek'hule ea ATP, e ka bapisoa ka maemo le peterole, e hlokahalang bakeng sa ho sisinyeha ha koloi.

Haeba ATP e sa lekana, sele e ke ke ea sebetsa ka mokhoa o tloaelehileng. Ka lebaka leo, dysfunctions tse fapaneng li ke ke tsa hlaha eseng feela ka lisele tse haelloang ke ATP, empa le sethong kapa lithong tsohle tseo li li etsang. Kaha ATP e thehiloe mitochondria ho tloha mafura le lik'habohaedreite, khaello ea phepo e nepahetseng e lebisa ho sena.

Ho tsoekere ea lefu la tsoekere, joala le mafu a mang, methapo e menyenyane ea mali e lula e koalehile ebile e sa fetisehe habonolo, ka lebaka leo methapo ea methapo e fumanehang ka har'a tishu ha e fumane limatlafatsi tse lekaneng, ka hona, e haelloa ke ATP. Ka lebaka leo, ts'ebetso ea methapo ea methapo ea kutlo ea hlaha, e iponahatsang e le tlolo ea kutlo ea methapo ea kutlo le motor motor, mme motho o utloa bohloko, ho chesa, ho tsitsipana le maikutlo a mang a sa thabiseng sebakeng seo letsoalo le amehileng le fetang ho lona.

Ho felisa maikutlo ana a sa thabiseng le mathata a ho sisinyeha, ho bohlokoa ho khutlisetsa phepo e nepahetseng ea sele. Thioctacid ke karolo ea bohlokoa ea potoloho ea metabolic, ka karolo eo karolo e kholo ea ATP e ka hlahisoang mitochondria, e khotsofatsang litlhoko tsa lisele. Ka mantsoe a mang, thioctacid ke ntho e ka felisang khaello ea phepo meleng ea methapo, 'me ka hona ea felisa lipontšo tse bohloko tsa neuropathy. Ke ka lebaka leo moriana o sebelisetsoang ho phekola polyneuropathies ea mefuta e fapaneng, ho kenyeletsoa le joala, lefu la tsoekere, jj.

Ntle le moo, Thioctacid e na le litlamorao tse kang tsa antitoxic, antioxidant le insulin. Ha e le antioxidant, sethethefatsi se sireletsa lisele tsa litho tsohle le lits'ebetso hore li se senngoe ke li-radicals tsa mahala tse entsoeng nakong ea ts'enyo ea lintho tse fapaneng tsa kantle ho naha (mohlala, thato ea lirafshoa tse boima, likaroloana tsa lerole, livaerase tse fokolang, joalo-joalo) tse kene 'meleng oa motho.

Matla a antitoxic a Thioctacid ke ho felisa litlamorao tsa ho taoa ka ho potlakisa ho felisoa le ho se sebetse ha lintho tse bakang chefo ea 'mele.

Ketso e kang insulin ea Thioctacid ke bokhoni ba ho fokotsa khatello ea "glucose" maling ka ho eketsa ts'ebeliso ea eona ke lisele. Ka hona, ho batho ba nang le lefu la tsoekere, thioctacid e fokotsa boemo ba tsoekere maling, e nolofatse boemo bo akaretsang mme e sebetsa ho fapana le insulin ea eona. Leha ho le joalo, ts'ebetso ea eona ha e ea lekana ho nkela insulin ea eona ka botlalo, kahoo ka lefu la tsoekere, o tla tlameha ho nka lipilisi tse theolang tekanyo ea tsoekere, kapa ho kenya insulin. Leha ho le joalo, ha u sebelisa Thioctacid, o ka fokotsa haholo litekanyetso tsa matlapa kapa insulin ho boloka maemo a tsoekere ea mali ka har'a mofuta o amohelehang.

Thioctacid e na le phello e matla ea hepatoprotective mme e ka sebelisoa e le karolo ea kalafo e rarahaneng ea mafu a fapaneng a sebete, joalo ka hepatitis, cirrhosis, joalo-joalo ho ekelletsa moo, li-acid tse mpe tse nang le mafura a mangata (li-lipoprotein tse tlaase le tse fokolang haholo) li hlahisoa, tse tsosang nts'etsopele ea atherosulinosis, lefu la pelo le tse ling. mafu a methapo ea pelo. Ho fokotseha ha mahlakore a mangata a "kotsi" ho thoe ke phello ea hypolipidemic ea Thioctacid. Ka lebaka la phello ena, atherosulinosis e thibetsoe. Ntle le moo, thioctacid e fokotsa tlala, e senya li-amana tsa mafura mme e thibela tse ncha ho bokellana, tse sebelisoang ka katleho ho fokotsa boima ba 'mele.

Matšoao a ho sebelisoa

Letšoao le ka sehloohong bakeng sa ts'ebeliso ea Thioctacid ke kalafo ea matšoao a neuropathy kapa polyneuropathy ho lefu la tsoekere kapa joala bo tahang.

Ntle le moo, Thioctacid e bontšoa hore e sebelisoa e le karolo ea kalafo e rarahaneng bakeng sa maemo kapa maloetse a latelang:

• Atherosclerosis ea likepe tse fapaneng, ho kenyelletsa le coronary,
• Lefu la sebete (hepatitis le cirrhosis),
• Ho chefo ka letsoai la tšepe tse boima le lintho tse ling (esita le grebe e boreleli).

Tharollo Thioctacid 600 T - litaelo tsa tšebeliso

Maemong a tebileng a lefu lena le matšoao a matla a neuropathy, ho khothalletsoa hore moriana o sebelisoe kahare bakeng sa libeke tse 2 ho isa ho tse 4, ebe o fetohela taolong ea nako e telele ea Thioctacid ho 600 mg ka letsatsi. Tharollo e fanoa ka kotloloho kahare, butle, kapa e sebelisoa ho lokisa tharollo bakeng sa tsamaiso ea methapo. Bakeng sa sena, litaba tsa ampoule e le 'ngoe li tlameha ho kenngoa ka bongata ka bongata (mohlomong bonyane) ba saline ea' mele. Ke letsoai la 'mele feela le ka sebelisoang bakeng sa ho hlapolla.

Ka neuropathy e matla, Thioctacid e tsamaisoa ka mokhoa oa methapo ka tharollo ea tharollo e entsoeng ka 600 mg ka letsatsi bakeng sa libeke tse peli ho isa ho tse nne. Ebe motho o fetisetsoa litekanyetsong tsa tlhokomelo - 600 mg ea Thioctacid BV ka letsatsi ka mokhoa oa litafole. Nako ea kalafo ea tlhokomelo ha e fokotsehe, 'me ho itšetlehile ka tekanyo ea ho thatafala le ho nyamela ha matšoao, ho felisoa ha lintho tse senyehang. Haeba motho a amohela infusions ea Thioctacid sepetlele sa letsatsi, ka mafelo-beke u ka nkela tsamaiso ea methapo ea lithethefatsi ka matlapa a noo e tšoanang.

Melao ea ho hlahisoa ha tharollo ea Thioctacid

Tekanyetso eohle ea letsatsi le letsatsi ea lithethefatsi e lokela ho fanoa ka infravenous e le 'ngoe. Sena se bolela hore haeba motho a hloka ho amohela 600 mg ea Thioctacid, joale ampoule e le 'ngoe ea mohopolo e nang le bophahamo ba 24 ml e lokela ho ts'oaroa ka bongata ba saline ea' mele, mme e kenelle ka bongata bo fumanoeng ka nako. Ho kenella ha tharollo ea Thioctacid ho etsoa butle, ka lebelo eseng kapele ho feta metsotso e 12 Nako ea tsamaiso e itšetlehile ka palo ea 'mele. tharollo. Ka mantsoe a mang, li-250 ml tsa tharollo li tlameha ho tsamaisoa nakong ea metsotso e 3040.

Haeba thioctacid e fanoa ka mokhoa oa ente e kenang kahare, joale tharollo ho tsoa ho ampoule e huleloa ka har'a syringe ebe moqomo oa litlolo o khangoa ho eona. Tsamaiso ea methapo e lokela ho tsamaea butle le ho qeta bonyane metsotso e 12 bakeng sa 24 ml ea ho tsepamisa mohopolo.

Kaha tharollo ea Thioctacid e tsotella leseli, e lokela ho lokisoa hang-hang pele ho tsamaiso. Li-ampoules tse nang le mohopolo li boetse li lokela ho tlosoa ho tloha hang hang pele li sebelisoa. Nakong eohle ea infusion, ho thibela litlamorao tse mpe tsa leseli tharollo e felileng, ho hlokahala hore o koahele sejana moo se behiloeng ka foil. Tharollo e felileng ka setsing se koaelitsoeng ka foil e ka bolokoa nako e telele ho isa ho lihora tse 6.

Bokhachane le pelehi

Ka bomalimabe, tlhaiso-leseling ea lithuto tse entsoeng hona joale le sephetho sa tlhahlobo ea ts'ebeliso ea Thioctacid ha li lumelle qeto e sa utloahaleng mabapi le polokeho ea lithethefatsi ho basali baimana le bo-mme ba anyesang. Ha ho na datha e netefalitsoeng le e netefalitsoeng mabapi le phello ea Thioctacid kholong le khōpong ea lesea, hammoho le ho kenella ha lona ka lebeseng la matsoele. Leha ho le joalo, ntho e sebelisang theoretically e sebetsang Thioctacid e bolokehile ebile ha e na kotsi ho batho bohle, ho kenyeletsoa basali ba bakhachane.

Empa ka lebaka la tlhaiso ea data e netefalitsoeng mabapi le polokeho ea moriana, ha ea lokela ho sebelisoa nakong eohle ea kemolo. Basali ba baimana ba lumelloa ho sebelisa Thioctacid tlasa tlhokomelo mme ba laetsoe ka tieo ke ngaka ha feela phaello e reriloeng e feta likotsi tsohle tse ka bang teng. Ha u sebelisa Thioctacid ke bo-'mè ba anyesang, ngoana o lokela ho fetisetsoa metsoako ea maiketsetso.

Ho sebelisana le lithethefatsi

Thioctacid e fokotsa katleho ea Cisplastine, ka hona, ka ts'ebeliso ea bona e ts'oanang, litekanyetso tsa morao-rao li lokela ho eketseha.

Thioctacid e kena khokahanong ea lik'hemik'hale le tšepe, ka hona e ke ke ea sebelisoa ka nako e le ngoe le litokisetso tse nang le likhakanyo tsa tšepe, magnesium, calcium, aluminium, jj. Ho hlokahala ho tsamaisa tšebeliso ea Thioctacide le litokisetso tse nang le likhomphutha tsa tšepe ka lihora tse 4 - 5. Ho nepahetse ho nka Thioctacid hoseng, le litokisetso ka tšepe - thapama kapa ka shoalane.

Thioctacid e ntlafatsa phello ea insulin le lithethefatsi tse theolelang tsoekere ea mali (lithethefatsi tse fokotsang lipid), ka hona, litekanyetso tsa bona li ka hloka ho fokotsoa.

Lino tse tahang li fokotsa katleho ea thioctacid.

Thioctacid ha e lumellane le tharollo ea tsoekere (tsoekere, fructose, Ringer, jj.).

Ka tsela e loketseng

Tharollo ea thioctic acid e tsamaisoa ka tekanyetso ea 600 mg ka letsatsi matsatsi a 14 ho isa ho a 30. Mohlomong tsamaiso e kenang butle ea mofuta o felisitsoeng oa ho tsepamisa maikutlo kapa ka ho hlophisoa ha tharollo bakeng sa tsamaiso ea methapo. Tekanyetso ea letsatsi le letsatsi e kenngoa ka moriana o le mong. Ho enta ha lintho tse sa fetoloang ho lokela ho lula bonyane metsotso e 12. Nako ea tsamaiso ea marotholi ho latela boholo ba saline mme e lokela ho nka bonyane halofo ea hora bakeng sa 250 ml.

Alpha lipoic acid e tsotella leseli. Tharollo ea tsamaiso e lokiselitsoe hang-hang pele e sebelisoa, sejana ka eona se lokela ho koaheloa ka foil nakong eohle ea infusion, ho thibela leseli ho kena mokelikeli o lokiselitsoeng. Bophelo ba sehatsetsing ba tharollo e joalo tlasa maemo a fifatsang ke lihora tse 6. Ka tsamaiso ea methapo ea kutloelo-bohloko, ampoule e tlosoa sephuthelong pele feela ka ente.

Matlapa a Thioctacid

Foromo ea letlapa e hloka ho nka moriana ka mpeng e se nang letho metsotso e 30 pele ho lijo tsa hoseng. Letlapa le lokela ho metsoa ka botlalo bonyane metsi a ka bang 100 di ml. E ka se ts'oaroe, e arotsoe likarolo kapa e silakantsoe. Sekhahla sa letsatsi se nkuoa 1 nako. Thupelo ena e etselitsoe tšebeliso ea nako e telele (bonyane likhoeli tse 1-2), hobane ntho e sebetsang ha e bokelle liseleng tsa 'mele. Ho a khonahala ho etsa kopo hape hape (ho fihlela makhetlo a 4 ka selemo) kamora ho buisana le ngaka ea hau.

Lipehelo tsa thekiso le polokelo

Setlhare se fanoa ka taelo e tsoang ho ngaka. Ha u reka, o lokela ho ela hloko ho latela melao ea polokelo ea lithethefatsi le bophelo ba eona ba selateng. Tharollo le matlapa a lokela ho bolokoa sebakeng se pholileng se lefifi ka mocheso o sa feteng 25 ° C. Li lokela ho sireletsoa ho bana le ho qoba khanya ea letsatsi ka kotloloho. Bophelo ba matlapeng a matlapa ke lilemo tse 5, tharollo e tsepamisitsoeng - lilemo tse 4.

Lithethefatsi tse latelang li ka nkuoa e le li-analogues tsa sebopeho:

• Berlition - e na le ntho e tšoanang, empa e teng ka har'a khatello e tlase.
• Oktolipen - e na le litšenyehelo tse tlase, empa, ho latela bakuli, ho na le litlamorao tse ngata.
• Tialepta, Thiolipon, Neuroleepone - matlapa a entsoeng ka Seukraine a nang le bioavailability e tlase le lenane le lesesaane la lipontšo (li laetsoe khahlanong le lefu la tsoekere la polyneuropathy).

Theko ea Thioctacid

U ka reka matlapa 'me ua tsepamisa maikutlo khoebong ea litlatse le inthaneteng ka litheko tse latelang:

Tharollo ea entetso

Theko ka pakete ea li-pcs tse 30, li-ruble

Theko ka pakete ea li-pcs tse 100, li-ruble

Palo ea li-ampoules, li-pcs

Olga, Thioctacid ea lilemo li 23 o ile a laeloa hore e be karolo ea kalafo e felletseng ea ntate oa ka ho tsoa ho lefu la sebete la mokokotlo, le ileng la hlaha boteng ba hae khahlanong le ts'ebeliso ea joala. Kamora thupelo, sebete se mo tšoenya hanyane, boemo bo akaretsang le bona boa ntlafala. Rea tšepa hore puso e pheta-phetoang e tla fana ka ts'ebetso e kholo le tsoelo-pele e tla matlafala, 'me sephetho se fihlelletsoeng se tla hokahanngoa.

Aleksey, ea lilemo li 45 ke ntse ke nka Thioctacid ho theola matsoele a maoto le matšoao a polyneuropathy a nkhathatsang ka lebaka la lefu la tsoekere. Ke qetile lilemo tse 'maloa ke sebelisa lithethefatsi ka matlapeng. Ke nka matsatsi a 14 makhetlo a 2 ka letsatsi le khoeli e 'ngoe hoseng. Kamora eona, motho o ikutloa a le betere, khatello ea tsoekere e fokotseha, mme maoto ha a amehe.

Anastasia, ea lilemo li 40 Tlhahlobo ea ka ea lefu lena - hepatitis - e hloka kalafo e sa feleng. Haufinyane tjena, ngaka e ile ea mpeela Thioctacid le Maksar ho sireletsa lisele tsa sebete. Kamora kalafo, ke ikutloa ke le betere, ke tšoaretsoe. Ke lumela hore khetho ea morero ona ke phetoho e kholo nalaneng ea ka ea bongaka, hobane pele ho eona ho ne ho se na phello e tšoarellang.

Svetlana, ea lilemo li 50. Tšebeliso e mpe ea tahi ea monna oa hae e ile ea lebisa taba ea hore maoto a hae a qala ho nkuoa, a re "ke" k'hothone ". Ngaka e tsoang lefapheng la litlhare e sebelisang lithethefatsi e ile ea mo etsetsa kemiso ea ho amoheloa ha hae, e neng e kenyelletsa Thioctacid. Thupelo eo ea tahi e fane ka litholoana tse ntle - kamora libeke tse 'maloa a emisa ho tletleba ka maoto. Ka tlase ke litšenyehelo tsa eona tse phahameng. Empa e hlile ea thusa.

Litla-morao tsa Thioctacid

Tse tloaelehileng tsa ho tsepamisa maikutlo le matlapa a Thioctacid ke litla-morao, e leng matšoao a bakoang ke ho fokotseha ha tsoekere ea mali, joalo ka ho tsekela, ho nyekeloa ke pelo, ho fufuleloa haholo, hlooho e bohloko le pono e habeli.

Ts'oarello ea Thioctacid e ka baka litlamorao tse latelang tse tsoang ho litho le litsamaiso tse fapaneng:
1.Ho tsoa ho tsamaiso ea methapo e bohareng:

• Maqhubu
• Pono e habeli (diplopia)
• Haeba moriana o fanoa ka potlako haholo, keketseho ea khatello ea methapo, ho utloa khatello ea mali hloohong, le ho phefumoloha moea, tse sa hlokahaleng kalafo kapa ho hlakoloa ha thioctacide, lia khonahala.

• Letata letlalong,
• Urticaria,
• Ho hlohlona
• Ho thothomela ha anaphylactic,
• Eczema
• Bofubelu ba letlalo.

• Li-hemorrhages tse nyane letlalong kapa mucous membrane (petechiae),
• Tloaelo ea ho tsoa mali
• Ts'ebetso ea mokhathala o senyehileng,
• Morero
• Thrombophlebitis.

• Nausea
• Ho phomola
• Tlolo ea tatso (tatso ea tšepe) molomong).

Matlapa a Thioctacid e ka tsosa litlamorao tse latelang:

• Nausea
• Ho phomola
• Bohloko ba ka mpeng
• Letšollo
• Letlalo la letlalo
• Urticaria,
• Ho hlohlona
• Ho thothomela ha anaphylactic,
• Liphetoho
• Tsietsing
• Jaundice

Thioctacid (BV, 600) - li-analogues

Hajoale ho na le litokisetso tse nang le thioctic acid 'marakeng oa meriana ea linaha, empa ha se lipapatso tsa Thiotacid, kaha li na le mofuta o fapaneng oa tokollo mme ka ho latellana, tahlehelo ea thepa e sebetsang, ho amoheloa ka tlase.Ntle le moo, ho fokotsa litšenyehelo tsa ho paka, litekanyetso tse tlase tse nang le litafole tse fokolang lia fumaneha, 'me ka lebaka leo, tlhahlobo e fokolang ea phekolo - likhoeli tse 3 - e theko e boima haholo, haholo ha kamohelo e le telele, ho feta selemo. Tšusumetso ea kalafo ea litlhare tse tloaelehileng e ne e sa bapisoe le thioctacid; "Li-analogues" tse ling li ipeha boemong ba hore ke lithethefatsi tse entsoeng ke Europe, empa ntho e sebetsang e rekoa Chaena, lintho tsa ballast lia eketsoa, ​​ka hona o hloka ho ba hlokolosi haholoanyane mabapi le se ka har'a sephutheloana.