Litaelo tsa ho sebelisoa ha Glidiab MV

Phekolo ea lefu la tsoekere ha se phetoho ea lijo feela, empa le ts'ebeliso ea meriana e khethehileng.

Ka lefu la mofuta oa 2, hangata batho ba fuoa lithethefatsi ho fihlela glycemia e tloaelehileng. Motsoako o mong o joalo ke Glidiab MV.

Tlhahisoleseling ka kakaretso, sebopeho le mofuta oa tokollo

Lithethefatsi Glidiab MV ke e 'ngoe ea litokollo tsa sulfonylurea (meloko e 2), ka hona e reretsoe ho susumetsa lisele tsa beta tse fumanehang manyeme.

Lithethefatsi li hlahisoa tikolohong ea Moscow ke k'hamphani ea meriana Akrikhin mme e nkuoa e le analogue ea matlapa a hypoglycemic Diabeteson MV, e entsoeng Fora. Moemeli o na le foromo ea tekanyetso e khetholloang ka tokollo e fetotsoeng.

Setlhare se fumaneha ka mokhoa oa matlapa a nang le whitish tint. Li tšoana le ponahalo ea meqomo ea litebele. Setlhare sena se fumaneha ka mekotla ea matlapa a 30 kapa 60.

Ha e bapisoa le Diabeteson MV, e nang le litekanyetso tsa 0,06 g, Glidiab MV e na le halofo ea karolo e sebetsang (0,03 g).

• Gliclazide ke eona ntho ea mantlha,
• selulose (microcrystalline),
• hydroxypropyl methylcellulose,
• magnesium stearate,
• Lero

Bakuli ba bangata ba fuoe Glidiab 80, e nang le ntho e sebetsang, eseng 30 mg, empa 80 mg ho pilara e ngoe le e ngoe.

Ketso ea pharmacological

Likarolo tsa Glidiab MV li ama 'mele ka tsela e latelang:

• ho potlakisa secretion ea insulin e hlahisoang ka makhopho a pancreas,
• eketsa kutloisiso ea lithane ho qoqotho e hlahisitsoeng,
• fokotsa nako ea lijo ho fihlela ha ho tsoa insulin,
• Tlas'a tšusumetso ea lithethefatsi tsena, secretion ea insulin e khutlisetsoa methating ea pele ho bapisoa le lithethefatsi tse ling tsa sulfonylurea,
• ntlafatsa ts'ebetso ea microcirculation ka lebaka la ho putlama ha lisele tsa liplatelete, ho khutlisetsa tumello ea lerako la vascular le kotsi e tlase ea micothrombosis,
• fokotsa glycemia,
• thusa ho felisa protenuria,
• fokotsa lebelo nts'etsopele ea retinopathy,
• kenya letsoho ho fokotsa boima ba 'mele, ho latela lijo tse tlamang.

Mofumahali

Ts'ebetso ea ho amoheloa, ho hasoa 'meleng, metabolism le ho pepeseha ha likarolo ho etsahala ka tsela e latelang:

1. Suction. Setlhare se batla se anngoe ka ho felletseng ka tšilo ea lijo (gastrointestinal tract). Ts'oarello ea eona e eketseha ka plasma hanyane ka hanyane, e fihla hofihlella ho tloha motsotso oa tsamaiso kamora lihora tse 6 kapa tse 12. Lits'ila ha li ame sekhahla sa ho amoheloa. Moriana o sebetsa lihora tse 24.
2. Tsamaiso. Puisano le liprotheine tsa plasma le likarolo tsa lithethefatsi li behiloe ho 95%.
3. Metabolism. Ts'ebetso ena e etsahala sebeteng, e khetholloang ka ho thehoa ha li-metabolites tse lumellanang.
4. Ho tsala. Excretion e etsahala ka liphieng ka sebopeho sa metabolites, ke 1% feela ea moriana o tsoang ka moroto. Ho felisoa ha halofo ea bophelo ba lithethefatsi ho etsahala ka lihora tse 16.

Mekhoa ea drugacokinetic ea lithethefatsi ho bakuli ba tsofetseng ha e fetohe.

Matšoao le contraindication

Matlapa a Glidiab MV ke lithethefatsi tsa hypoglycemic, ka hona, li sebelisoa kalafo ea lefu la tsoekere la mofuta oa 2, ha mekhoa e meng ea ho fokotsa tsoekere e sa khutlisetse letšoao ho tloaelehileng.

Lintho tse amanang le tšebeliso ea lithethefatsi ke tsena:

• ketoacidosis
• ts'ebetso ea menoana e sa sebetseng,
• Type 1 lefu la tsoekere
• coma (lefu la tsoekere kapa hyperosmolar),
• ts'ebetso
• likotsi
• bowel,
• boimana
• maemo a bakang hypoglycemia (mohlala, mafu a mofuta o sa foleng),
• leukopenia
• ho chesa haholo
• hypersensitivity ea lintho tse sebopeho sa sehlahisoa,
• sefuba.

Litaelo tsa tšebeliso le litaelo tse ikhethang

Tekanyetso ea moriana e ipapisitse le litšobotsi tsa mofuta oa lefu la tsoekere le lipontšo tsa lona, ​​ka hona le khethoa ke ngaka ka bonngoe ho mokuli ka mong.

Qalong ea ho sebelisa moriana o nooa moriana oa 30 mg kapa 1 pilisi. Ho latela boemo ba mokuli nakong ea phekolo, palo ea lintho tse sebetsang ka letsatsi e ka nyoloheloa ho 120 mg (lethal dose le phahameng).

Matlapa a nooa ka molomo nakong ea lijo tsa hoseng (hang ka letsatsi). Ho senyeha ha renal (e nang le "creatinine" ho tloha ho 15 ho isa ho 80 ml / min) ha ho hloke tokiso ea tekanyetso.

Qalong ea kalafo ea lithethefatsi le ho fihlela lethalamo le hlokahalang le khethoa, hangata bakuli ba nang le hypoglycemia ha baa lokela ho etsa mosebetsi o hlokang karabelo e potlakileng kapa tlhokomelo e eketsehileng.

Basali ha baa lokela ho sebelisa lithethefatsi nakong ea ho beleha ngoana, hammoho le matsoele.

Tekanyo e mpe ea liphio kapa sebete e thibela ts'ebeliso ea moriana esita le litekanyetso tse fokolang.

1. Tlhokahalo ea ho fihlela katleho ea kopo ke ho latela ho ikoetlisa le ho ikoetlisa ka tsela e itekanetseng. Lijong tsa letsatsi le letsatsi, lik'habohaedreite li lokela ho ba teng ka tekanyo e fokolang.
2. Ho bohlokoa hore glycemia e hlahlojoe pele le ka mor'a lijo e le hore litekanyetso li ka fetoloa ho latela sephetho sa litekanyo.
3. Bakeng sa ho buuoa kapa lefu la tsoekere le bolileng, moriana o lokela ho nkeloa sebaka ka ente ea insulin.
4. Bakeng sa ho qoba ho hlaha ha hypoglycemia, hammoho le karabelo e kang ea discriram, u se ke ua noella joala.
5. Ho thibetsoe ho tlola lijo, ho qoba ho ja lijo tse bobebe ka nako ea tlala.
6. Pele ho mosebetsi o boima oa 'mele, tekanyetso e lokela ho fokotsoa.

Lithethefatsi tse amehang ka ho fetisisa ho li-hypoglycemic ke:

• batho ba botsofaling
• Bakuli ba sa tsebeng ho ja hantle,
• batho ba nang le mmele o fokolang
• bakuli ba nang le lefu le kang pituitary-adrenal insufficiency.

Litla-morao le ho sebelisa overdose haholo

Ho nwa lipilisi ho ka baka karabelo e latelang ho motho:

• mabapi le tsamaiso ea endocrine - hypoglycemia e nang le maikutlo a hlooho ea hlooho, ho fufuleloa, bofokoli, khatello ea maikutlo, ho thothomela, ho ferekana ha kelello, pono e sa sebetseng le tšebelisano ea motsamao.
• ho tloha ka mpeng - dyspepsia, anorexia, ho tsitsipana ha sebete,
• leukopenia, thrombocytopenia, anemia,
• lipontšo tsa lintho tse kulang (ho hlohlona, ​​lekhopho, kapa urticaria).

Ka moriana o feteletseng oa lithethefatsi, hypoglycemia e etsahala. Ho felisa matšoao a eona, ho lekane ho nka lik'habohaedreite tse ngata, ha feela motho a tseba. Maemong moo mokuli a ke keng a hlola a ja lijo a le mong, o lokela ho fuoa tharollo ea glucose e kenang (40%) le ente ea ente ea glucagon. Kamora ho khutlela ho motho ea nang le lefu la tsoekere, o ntse o hloka ho luma ho qoba ho theoha ha tsoekere e ngata khafetsa.

Tšebelisano le meriana e meng le li-analogues

Ts'ebeliso ea lithethefatsi tse ling hammoho le Glidiab MV e ka ntlafatsa kapa ea fokotsa sephetho sa hypoglycemic.

Phekolo e kopaneng le lithethefatsi tse kang:

• Li-inhibitors,
• antifungal agents (fluconazole),
• NSAIDs
• antihistamines
• Fibrate
• lithethefatsi tse khahlanong le lefuba
• Salicylates,
• Pentoxifylline
• Ethanol
• lithethefatsi tse thibelang secretion ea tubular.

Phello ea hypoglycemic e hatelloa ha e kopantsoe le litlhare tse latelang:

• barbiturates
• thiazide diuretics,
• Furosemide
• li-hormone tsa ho boloka tšebetso ea qoqotho e sebetsa hantle,
• Litokisetso tsa lithium
• estrogens
• mekhoa ea ho thibela pelehi ka molomo.

Har'a litlhare tse nang le litlamorao tse tšoanang le tsa Letlapa la Glidiab MV, ho fanoa ka tse latelang hangata:

• Meglimide
• Aletare
• Glibetic,
• Clay,
• Glimepiride
• Eglim
• Botle
• Glibenclamide,
• Glurenorm.

Lintho tsa video tse mabapi le lefu la tsoekere, kalafo ea lona le thibelo:

Maikutlo a bakuli le lingaka

Ho tsoa ho litlhahlobo tsa mamello, re ka fihlela qeto ea hore moriana o mamelletsoe hantle le ts'ebetso ea ona. Leha ho le joalo, lingaka li tsitlella ho sebelisa lithethefatsi ka mor'a ho buisana le setsebi.

Pheko e ntle haholo. Ka lebaka la khatello ea maikutlo e matla, ke ile ka ba le boima ba li kilo tse 30, leha ke ne ke sa fetole mokhoa oa ka oa ho ja. Ka lebaka leo, ke ile ka fumana tsoekere e phahameng ea mali. Ngaka e ntaetse hore ke noe matlapa a mabeli a Glidiab MV hoseng ho hong le ho hong, mme mantsiboea ho nooa Letlapa le le leng la Glucofage 1000. Ka lebaka la regimen ena ea kalafo, index ea glucose e ile ea theoha ke likarolo tse 4 mme e ntse e tsoela pele ho lula ho pota 7 mmol / L kamehla.

Kristina, mokuli, ea lilemo li 47

Setlhare se bonolo ho se sebelisa. Glidiab CF e na le likhohlano tse ngata, ka hona bakuli ha baa lokela ho inkela bona ntle le tumello e tsoang ho ngaka e eang teng. Hoa hlokahala hore kamehla u hlahlobe glycemia le ho sekaseka katleho ea kalafo ea lefu la tsoekere hammoho le endocrinologist. Ka mofuta oa kalafo o khethiloeng ka nepo, hoa khoneha ho potlakisa letšoao la tsoekere. Moriana ona o fuoa meriana le meriana, empa baahi ba nang le lefu lena ba e amohela mahala, ho latela tlhahlobo ea litsebi tsa tleliniki ea bona.

Victor Vladimirovich, ngaka

Theko ea matlapa a 60 a Glidiab MV ka har'a sephutheloana e ka ba li-ruble tse 200.