Ke eng e thusang Siofor? Litaelo, theko, litekolo le li-analogues

Siofor ke lithethefatsi tse tsoang sehlopheng sa Biguanide. Motsoako o ka sehloohong ke metformin, e 'nileng ea sebelisoa ho phekola lefu la tsoekere lilemo tse ngata.

Ho fapana le mahlahana a mang a antidiabetic, sethethefatsi se fokotsa tlhahiso ea tsoekere ka lisele tsa sebete, se thibela ho nkeloa ha sona likarolong tse holimo tsa mokokotlo, se eketsa tlhokeho ea mesifa, hape se fokotsa sekhahla sa ho senyeha hoa insulin 'meleng.

Litlamorao tse ka sehloohong tsa ho sebelisa litlhare:

• e theola le ho tsitsisa boemo ba hemoglobin ea glycosylated le glucose ea mali,
• tsoekere e ngata e fumanoang ke lisele tse ling,
• mamello e eketsehileng ho tsoekere ea mali.

• e fokotsa lipoprotein tse tlaase le tse tlase haholo,
• e na le antioxidant le phello e sirelletsang liseleng tsa lisele,
• normalizing boima ba 'mele ka botenya.

Setlhare sena se sebelisetsoa ho phekola lefu la tsoekere la mofuta oa 2.

Mefuta ea lithethefatsi

Motsoako oa litlhare o na le mefuta e mengata ea ho lokolloa, 'me kaofela ha oona oa beoa, e leng se etsang hore moriana o be bonolo haholo ho o fuoa hae.

• Siofor 500 - matlapa a masoeu, a bolelele, a koahetsoe, a tiisitsoe ka lithutsoana tse khethehileng tsa likarolo tse leshome le metso e mehlano, sephutheloana se seng le se seng sa karete se na le lithutsoana tse peli ho isa ho tse robeli,
• Siofor 850 - matlapa a tšoeu, a oblong, le ona a koahetsoeng, a pakile lithutsoana tsa likotoana tse leshome le metso e mehlano, ka pakete e 'ngoe le e' ngoe ea likarete tse tsoang ho lithutsoana tse peli ho isa ho tse robeli,
• Li-Siofor 1000 - matlapa a masoeu a nang le lesela le lenyenyane holimo, a na le khetla, le 'ona a tletse mekotla ea likotoana tse leshome le metso e mehlano, ka har'a pakete e le' ngoe ho tloha ho lithutsoana tse peli ho isa ho tse robeli ka matlapa.

Contraindication

Tlhaloso ea moriana o mong le o mong o kenyelletsa khaolo ea li-contraindication. Ha ho sa tsotelloe hantle karolo ena ea thupelo, ho na le kotsi e kholo ea mathata a mefuta e fapaneng.

Contraindication mabapi le ts'ebeliso ea Siofor e le moemeli oa lefu la lefutso:

• congenital hypersensitivity ho likarolo tsa moriana,
• mofuta oa 1 lefu la tsoekere, leseling,
• coma kamora hyperglycemia,
• ketoacids
• maemo a ho thothomela: ho ts'oaroa ha peloiogenic, chefo ea septic le Cardiogenic,
• tsitsipano moeling oa motlakase oa motlakase,
• mokhathala le ho ipolaisa tlala,
• ts'enyo e kholo ea ho baka 40% ea 'mele,
• tahlehelo ea mali a fetang litha e le nngwe le halofo tsa mali,
• ho buuoa ka tlasa ho buoa ka thipa kapa ka metso
• mafu a tšoaetsanoang a lefu la genitourinary system le bronchopulmonary,
• ho thijoa ke mala
• gastrointestinal motility mafutsana,
• malbigestion le malabsorption,
• maloetse a tsamaiso ea endocrine: thyrotooticosis, autoimmune thyroiditis, lefu la bronze, lefu la lefu la sethoathoa mellitus,
• febrile syndrome
• tšebeliso e telele ea joala le nts'etsopele ea chefo ea joala,
• temallo
• boimana ho liotsoa tse tharo kaofela,
• sefuba
• sehlopha sa batho ba ka bang lilemo tse leshome le batho ba lilemo tse mashome a tšeletseng a metso e mehlano,
• hlahala lesapo la mokokotlo le mokokotlo oa lesapo le kotsi la ho nyemana le mongobo.

Tekanyetso e tla latela hore na moriana o tla sebelisoa hammoho le mahlahana a mang a antidiabetes. Tekanyetso e nepahetseng e khethoa ke endocrinologist kamora ho etsa tlhahlobo ea bongaka. Setlhare se ka ba le ligrama tse 0,5, 0,85 le 1 ea ntho ea bohlokoa.

Pheko ea Siofor feela

Ba qala ho nka moriana o nang le litekanyetso tsa ligrama tse 0,5 hang kapa habeli ka letsatsi kapa ho tsoa ho ligrama tse 0,85 hang ka letsatsi. Libeke tse peli kamora ho qala ts'ebetso, ho se na litlamorao tse mpe, eketsa tekanyetso butle-butle ho isa ho 1.5-2 gr. Haeba butle-butle u eketsa bongata ba lithethefatsi, litla-morao li tla hlaha ka tekanyo e nyane haholo.

Pheko ea ho kopanya

Hangata, motsoako oa siofor le insulin o sebelisoa kalafong ea tsoekere. Ka nako e ts'oanang, ba qala ho nwa matlapa ka litekanyo tsa ligrama tse 0,5, beke e 'ngoe le e' ngoe ba e eketsa ka gram e 'ngoe ho fihlela e fihla tekong e tloaelehileng ea letsatsi le letsatsi (ligrama tse 3-4). Palo ea liente tsa insulin e khethoa ka ho lekanya tsoekere ea mali.

Litaelo tsa ho sebelisoa

Siofor, eo taelo ea hae ea ts'ebeliso e sa bake mathata a itseng, e nkuoa hang kapa habeli ka letsatsi (ho latela tekanyetso e boletsoeng ke setsebi). Ho khothalletsoa ho nka matlapa pele ho lijo tse kholo, u li hlatsoa ka khalase ea metsi a hloekileng. Ha ho amohelehe ho nwa letlapa ka joala, litholoana tse bolila kapa lero la meroho, hammoho le lihlahisoa tsa lebese, kaha sena se tla ama hampe thepa ea ntho eo.

Litaelo tse khethehileng

Haeba moriana o laetsoe hammoho le li-sulfonylurea derivatives kapa insulin, ho hlokahala hore u nahane ka boemo ba tsoekere maling maling ka linako tse fapaneng tsa letsatsi. Ho hlokahala hape ho etsa tlhahlobo ea hemoglobin ea glycosylated.

Kamora ho sebelisa moriana ona, ho khothalletsoa ho nka kakaretso ea urinalysis le biochemical ka moroto le mali ka likhoeli tse ling le tse ling tse tšeletseng, hape le ho tseba sekhahla sa ho hlohlona ka nakoana. Liteko tsena li u fa monyetla oa ho tseba boemo ba liphio le phello ea lithethefatsi tsamaisong ea moroto.

Haeba mokuli a e-na le lefu la matšoafo, lefu la sebete, kapa a tšoaetsanoang le mafu a likokoana-hloko, o lokela ho tsebisa ngaka ea hau hanghang ka sena 'me u buisane ka maqheka a kalafo e eketsehileng.

Haeba mokuli a lokela ho hlahlojoa ka ho hlahisoa ha karohano ea radiology kapa ho buuoa, moriana o hlakoloa matsatsi a mabeli pele ho ts'ebetso.

Ho anyesa ho se lumellane le ho sebelisa moriana. Litlhahlobo tsa litsebi li netefatsa hore moriana o kentsoe lebeseng la matsoele. Ha u rera ho ima nakong ea likhoeli tse 'maloa ka mor'a ho qala ho sebelisa moriana, o lokela ho tsebisa ngaka e tlang ka sena mme o nke sebaka sa sona.

Ho sebelisana 'moho le lithethefatsi tse ling

Ha lithethefatsi tse 'maloa li fumanoa' meleng hang, sena se ka fetola matla a tsona. Lefu la tsoekere leo ho leng thata ho le laola le lebisa ho tšebeliso ea li-agents tse 'maloa tsa hypoglycemic hang, tse ka bakang litlamorao tse mpe.

Litlamorao tsa ho sebelisana ha Siofor le lintho tse ling tsa kalafo:

• loop, thiazide le phokotso e phodisang potasiamo e fokotsa phokotso ea tsoekere,
• glucocorticosteroids, lithibela-pelehi tsa li-hormone, lithethefatsi tsa li-hormone tsa thobalano tsa banna le basali (tse nang le testosterone, estrogens) li ama hampe ts'ebetso ea hypoglycemic,
• nifedipine, nicardipine e eketsa ho kenngoa ha moriana ka seterateng se ka holimo sa mpa,
• insulin le lintho tse kang insulin, litokisetso tsa sulfonylurea li eketsa phello e kholo ea lithethefatsi mme li ka baka komello,
• antidepressants, angiotensin-converting enzyme inhibitors le lithibela-mafu tse ling le tsona li eketsa katleho ea siofor,
• ha o nka cimetidine, setlama sa setlama se tsoang 'meleng sea senyeha, se ka bakang ketoacidosis,
• ho nwa joala ho eketsa kotsi ea mmuso oa ketoacidotic makhetlo a mangata,
• Lintho tse nang le iodineine tse nang le iodineine e kopantsoeng le siofor li ka baka karohano e mpe ea bokuli le edema ea Quincke le nts'etsopele ea morao ea ts'oaetso ea anaphylactic.

Litlamorao

Siofor 500 e ka baka litlamorao tse itseng, tseo ha e le hantle ke tšobotsi ea ntho efe kapa efe ea lithethefatsi. Boholo ba tsona bo hlaha ka lebaka la tšebelisano ea motho ka mong ea likarolo tsa mantlha le tse ling tsa lithethefatsi ka li-receptors tsa 'mele.

Litlamorao tse tloaelehileng tsa ho nka Siofor:

• dyspepsia liponong tsohle: matšoao a ho ba le letsoai le pelo le bohale ha molomo, belching,
• ts'ebetso ea ho hlaka hoa gag, ho nyekeloa,
• lets'ollo le ho sokela,
• Khokahano ea khase ka setsing se ka tlase sa mpa,
• bohloko bo sithabetsang ka mpeng.
• ho ikutloa o khotsofetse ka mor'a ho ja lijo tse nyane,
• tatso e bohloko e hlabosang ea mathe e nang le ho ama tšepe,
• ho fokotseha ho matla ha tsoekere ea mali, ho lebisang maemong a hypoglycemic,
• syncope le syncope
• migraines le migraine vertigo,
• lethargy, ho tšoha,
• ho theola boima ba 'mele
• linako tse telele tsa khatello ea maikutlo, tse lateloang ke boitšoaro bo mabifi,
• hematopoiesis: megaloblastic anemia,
• phetoho ya boitshwaro
• Ho thothomela ha mabelo a holimo,
• ho otsela ho eketsehileng kapa ho hloka boroko,
• ho hlohlona ha letlalo,
• ho pepeta letlalo
• lekhopho le tsoang matlalong a mucous le letlalong,
• allergies le allergic reaction: Edincke's edema, anaphylactic makala,
• nts'etsopele ea ho hloleha ha renal haholo,
• Nts'etsopele ea ho hloleha ha sebete ho sa foleng.

Setlhare se maemong a mahareng a theko. Leano la litheko metseng e fapaneng ea lefats'e le fapana hanyane. Joalo ka litorotsoaneng tse kholo le profinseng, theko e tla ipapisa le hore na u fa litekanyetso li kae ngaka e u file eona. Phapang ea litšenyehelo tsa Siofor 500 le Siofor 1000 e bohlokoa haholo.

Karolelano ea litheko litoropong ho potoloha le lefatše:

1. Naheng ea Moscow le ea Moscow, moriana o ka fumanoa ka theko ea li-ruble tse 340 ho isa ho tse 850.
2. St. Petersburg, litšenyehelo tsa lithethefatsi li tla tloha ho li-ruble tse 350 ho isa ho tse 850.
3. Lifekthering tse toropong ea Chelyabinsk siofor li theko e boima ho tloha ho li-ruble tse 265 ho isa ho tse 340.
4. Makhemisi a Novosibirsk a rekisa lithethefatsi ka theko ea li-ruble tse 215 ho isa ho tse 800.
5. Sebakeng sa Lipetsk le sa Lipetsk, motho a ka fana ka li-ruble tse 212 ho isa ho tse 840 bakeng sa moriana.
6. Apotheken Rostov-on-Don e pepesa sehlahisoa sa kalafo ka theko ho tloha li-ruble tse 347 ho isa ho 860.
7. Ho Vladivostok, o ka reka lipilisi tsena ka theko ea li-ruble tse 234 ho isa ho 836.

Siofor, joalo ka moriana o mong le o mong, e na le menahano ea eona. Bongata ba tsona li fapana naheng e hlahisang. Mefuta e meng ea lithethefatsi e na le liphetoho tse nyane sebopeho sa tsona, e leng se etsang hore li khonehe bathong ba bang.

Mekhelo ea mantlha ea lithethefatsi:

1. Glucophage ke sethethefatsi se entsoeng ka Sefora se nang le phapang e itseng likarolong tse thusang tsa moriana. Theko ea meriana ea litlhare e tsoa ho li-ruble tse 122 ho isa ho tse 322.
2. Bagomet, ho fapana le lithethefatsi tse ling, e na le lithibelo tsa lilemo tse ling tsa ts'ebeliso: bathong ba ka holimo ho lilemo tse mashome a tšeletseng ba behiloe ka hloko e kholo. Karolo ea theko e tsoa ho li-ruble tse 110 ho isa ho 340.
3. Glycon ke sethethefatsi sa Canada. Hape, joalo ka li-analogues tse ling, e na le metformin, empa e fumaneha ka mokhoa oa litafole tse kentsoeng ka botlolong. Lifekthering u ka fumana ka theko e ntle ea li-ruble tse 219.
4. Glyminfor ke setlhare se tsoang k'hamphaning ea meriana e India. E baka litlamorao tse ling tse amanang le ho holofala ha mosebetsi oa ka mpeng. Maikutlo mabapi le lithethefatsi tsena a tsoakane. Theko e khothalletsoang likhoebong tsa meriana ke li-ruble tse 200.
5. Foromo Pliva - e na le liphetoho tse nyane molemong oa boitapiso. Theko ea ho qetela litlolong tsa meriana ke li-ruble tse 250.
6. Metfogamma ke lithethefatsi tsa Jeremane. Ha e sebelisoa ka nako e telele, e ka baka khaello ea vithamine e nyane. E rekisitsoe likhoebong ka theko ea li-ruble tse 180 ho isa ho tse 660.
7. Metformin e telele - ho fapana le metformin e tloaelehileng, e na le phello e tšoarellang. Theko e tsoa ho li-ruble tse 135 ho isa ho tse 262.

Bongata

Ha o sebelisa moriana o fetang tekanyetso e khothalletsoang ke lingaka, mokuli o tsoa le lactic acidosis (phetoho e lekantsoeng ea acid-'meleng).

Matšoao a sehlooho a lactic acidosis:

• ho nyekeloa
• ho hlatsa
• lets'ollo
• bohloko ba ka mpeng
• tlhahiso e eketsehileng ea khase,
• bohloko ba mesifa ea spasmodic
• boikutlo ba ho hloka moea.

Hape hoa khoneha nts'etsopele ea hypoglycemia, e fetelang ho coma ea hypoglycemic. Boemo bona bo tsamaisana le ho felloa ke kelello, khatello ea maikutlo, maikutlo a tšosang, ho fufuleloa ha moea o batang le moea o mobe.

Thuso ea pele bakeng sa hypoglycemia le lactic acidosis - ho ja tsoekere ka molomo le kahare.

U ka sebelisa tsoekere e nyane kapa mahe a linotsi. Kamora moo, mokuli o lokela ho isoa sepetleleng se ikhethileng, moo a tla hlahlojoa ke hemodialysis ho tlosa ntho e sebetsang 'meleng.

Siofor ke setlhare se sebetsang hantle sa hypoglycemic se nang le melemo ea bohlokoa le likotsi tse 'maloa. Ho bohlokoa ho hopola hore, pele ho tsohle, Siofor 500 le Siofor 1000 li thusa tsoekere e tlase ea mali, mme ho itšetleha ka litlhahlobo tsa ba li sebelisang e le lithethefatsi bakeng sa ho theola boima ba 'mele ha ho hlile ha ho na thuso. Phekolo efe kapa efe e lokela ho laeloa le ho amoheloa ke setsebi.

Sokolla foromo le sebopeho

Siofor e fumaneha ka mokhoa oa matlapa a koahetsoeng ka koae e tšoeu ea filimi.

Ntho e sebetsang ke metformin hydrochloride. Bophahamo ba eona litokisetsong ke 500 mg, 850 mg kapa 1000 mg, likarolo tse thusang: povidone, hypromellose, magnesium stearate, koae ea lifilimi: macrogol 6000, hypromellose, titanium dioxide.

Mali

Siofor, litaelo tsa tšebeliso li tiisa taba ena, e fana ka phokotso ea likhakanyo tsa tsoekere ea mali ea basal le ea postprandial. Ha e khothalletse secretion ea insulin mme ka hona ha e lebise ho hypoglycemia.

Ketso ea metformin (motsoako o sebetsang) mohlomong e thehiloe ho ts'ebetso e latelang: ho fokotseha ha tlhahiso ea tsoekere ka har'a sebete ka lebaka la thibelo ea gluconeogeneis le glycogenolysis, kholo ea mesifa ho insulin mme ka hona, ntlafatso ea ts'ebetso ea glucose ho potoloha le ts'ebeliso ea eona, ts'ebetso ea ts'oaetso ea glucose. .

Matlapa a Siofor a 500 mg, 850 mg kapa 1000 mg ka ketso ea bona ho synthetase ea glycogen e tsosa motsoako oa intracellular glycogen. Boholo ba liprotheine tsa liprotheine tsohle tse tsebahalang tsa glucose membrane lia eketseha.

Ho sa tsotelehe phello ea boemo ba glucose maling, sethethefatsi se na le phello e molemo ho metabolism ea lipid, e lebisang ho fokotseha ha cholesterol e felletseng, cholesterol e tlase le triglycerides.

Moriana "Siofor": litaelo tsa tšebeliso (ho nka)

Regimen le tekanyetso ea meriana, hammoho le nako ea kalafo, li khethoa ke ngaka e eang ho ipapisitse le boemo ba glucose maling a mokuli.

Batho ba baholo Ka monotherapy, tekanyetso e nepahetseng ea pele ea lithethefatsi ke 500 mg (1/2 piritsi. Siofor 1000 kapa 1 tablet. Siofor 500) makhetlo a 1-2 ka letsatsi kapa 850 mg (1 kiba. Siofor 850) nako e le ngoe ka letsatsi.

Matsatsi a 10-15 kamora ho qala kalafo ka moriana, keketseho e 'ngoe ea lethal (butle-butle) e ka khona ho latela bongata ba tsoekere maling maling ho ea ho lethal dose le tloaelehileng la letsatsi le letsatsi: matlapa a 3-4. 500 mg, matlapa a 2-3. 850 mg e le 'ngoe, matlapa a 2 Siofor 1000 mg.

Tabeng ena, tekanyetso e kholo e lumelloang ke 3000 mg ka letsatsi e arotsoe ka litekanyetso tse 3.

Bakeng sa bakuli ba fuoeng litekanyetso tse phahameng tsa lithethefatsi (2000-3000 mg ka letsatsi), ho ka khoneha ho khutlisoa matlapa a mabeli. 500 mg ka Letlapa le le leng 1000 mg.

Ha u fetisetsa bakuli kalafo ea lithethefatsi ka kalafo ka sethethefatsi se seng sa antidiabetes, ho bohlokoa ho emisa ho nka lijo tsa morao-rao ebe o qala ho noa matlapa a Siofora ho litekanyetso tse ka holimo.

Ka tšebeliso e kopaneng ea lithethefatsi le insulin, tekanyetso ea mantlha e tloaelehileng ke 500 mg makhetlo a 1-2 ka letsatsi kapa 850 mg 1 nako ka letsatsi. Nakong e tlang, lethalinyana le eketseha butle-butle hore e be e tloaelehileng letsatsi le letsatsi:

• Matlapa a 3-4 Siofor 500 mg
• Matlapa a 2-3 850 mg ka 'ngoe
• 2 tab. 1000 mg ka 'ngoe.

Etsa sena nako le nako bekeng e le 'ngoe. Tekanyetso ea insulin e thehiloe ho latela boemo ba glucose maling. Tekanyetso e kholo e lumelloang ke 3000 mg ka letsatsi e arotsoe ka litekanyetso tse 3.

Bana ba lilemo li 10 ho isa ho 18.Tekanyetso e tloaelehileng ea pele bakeng sa ts'ebeliso e kopaneng le insulin le monotherapy ke 500 mg ka makhetlo a 1 ka letsatsi kapa 850 mg 1 nako ka letsatsi.

Matsatsi a 10-15 kamora ho qaleha ha kalafo, keketseho e 'ngoe ea lethalamo e khonahala ho latela khatello ea tsoekere maling. Tekanyo e kholo e amohelang bana ke 2000 mg ka letsatsi e arotsoe ka litekanyetso tse 2-3. Tekanyetso ea insulin e ikemiselitse ho nahanela boemo ba tsoekere e maling.

Litlamorao

Ho nwa moriana ho ka baka karabelo tse mpe tse latelang:

• lekhopho la letlalo
• megaloblastic anemia,
• ho hloka takatso ea lijo
• ho nyekeloa, ho hlatsa,
• lets'ollo
• botlaela
• bohloko ba ka mpeng
• tatso ea tšepe e molomong
• hypoglycemia (e khahlanong le mofuta oa litekanyetso),
• ka kalafo ea nako e telele, nts'etsopele ea B12 hypovitaminosis (malabsorption) e khonahala,
• maemong a ikhethileng (ka lithethefatsi tse ngata tse feteletseng, boteng ba maloetse moo ho sebelisoang lithethefatsi ntle le tšebeliso ea joala), lactic acidosis e ka hlaha (e hloka ho khaotsa kalafo).

Analogues ea meriana "Siofor"

Litlhahlobo tse felletseng tsa ntho e sebetsang:

1. Sofamet.
2. Foromo.
3. Metospanin.
4. Metfogamm 1000.
5. NovoFormin.
6. Metfogamm 500.
7. Metphogamm 850.
8. Glyminfor.
9. Methadiene.
10. Metformin.
11. Bagomet.
12. Glucophage.
13. Glucophage Nako e telele.
14. Foromo Pliva.
15. Langerine.
16. Metformin hydrochloride.
17. Nova Met.
18. Glycon.
19. Gliformin.

Maemo a phomolo le theko

Theko e tloaelehileng ea Siofor ho la Moscow ke li-ruble tse 322. Ho Kiev, o ka reka matlapa (500 mg No. 60) bakeng sa 179 hizvnias, Kazakhstan - bakeng sa 1595 tenge. Minsk, litlhare li fana ka Siofor 850 No. 60 bakeng sa 9-10 bel. li-ruble. E fumaneha ho lithekisi ka lengolo la ngaka.

Mabapi le Siofor 1000, 850, 500, litlhahlobo tsa lingaka li ntle haholo, empa litsebi li tiisa hore lithethefatsi li lokela ho nkuoa feela ke bakuli ba nang le lefu la tsoekere, 'me ba sa phele hantle, ba lahlehetsoe ke batho ba boima ba' mele. Moriana o thusa ho khutlisetsa maemo a tloaelehileng a tsoekere hantle, hape, batho ba nang le lefu la tsoekere ba nkang boima ba 'mele ba tsebiso ea meriana.

Ka marang-rang u ka fumana litlhahlobo tse ngata tsa ba lahlehetsoeng ke boima ba 'mele ka thuso ea sesebelisoa sena, ba reng ha u se nka, takatso ea hau ea lijo e fokotsehile. Leha ho le joalo, litla-morao li tlameha ho lula li hopoloa. U ka nka meriana ntle le taelo ea ngaka.