Vasobral

Tse tsoang ho dihydrogenated ergot e tsosa serotonin le dopamine receptors tsamaisong ea methapo e bohareng ka ho thibela adrenoreceptors (alpha1-, alpha2-) liseleng tsa mesifa e bonolo. Kamora litekanyetso tse 'maloa tsa moriana, ho ikopisa lisele tse khubelu tsa mali le palo ea liplatelete haholo fokotseha. Lits'ebetso tsa metabolism le phallo ea mali bokong lia ntlafala. Li-tishu tsa Brain li fetoha tse kenang habonolo ho hypoxia.

Ho hlohlelletsa CNS ho fumanoa haholo ka lebaka la caffeine, e amanang le libaka tsa vasomotor le tsa phefumoloho, hammoho le cortex ea "cerebral". Boikutlo ba ho tepella bo fokotseha, ts'ebetso ea eketseha.

Litšoantšo tsa 3D

Mofumahali

α-Dihydroergocriptine ke ergot e tsoang ho dihydrogenated e thibelang α₁- le α₂-martorceptors. E na le dopaminergic, serotonergic effect, e fokotsa pokello ea methapo le erythrocyte, e fokotsa sekhahla sa lebota la vascular, e eketsa palo ea li-capillaries tse sebetsang, e ntlafatsa methapo ea mali le methapo ea metabolic bokong, hape e eketsa ho hanana ha lisele tsa boko ho hypoxia.

Caffeine e na le ts'ebetso ea kelello le e matlafatsang, e matlafatsang ts'ebetso ea mokokotlo mokokotlong oa mokokotlo, e eketsa ts'ebetso ea kelello le 'mele, e fokotsa mokhathala le ho otsela, e eketsa thabo ea kelello ea lesapo la mokokotlo, e thusa libaka tsa phefumoloho le tsa vasomotor, hape e na le phello ea maikutlo.

Litlamorao

Khafetsa ea ho ba teng ha liketsahalo tse sa thabiseng / karabelo e mpe ha u sebelisa moriana e hlahisoa ho latela gradation e latelang (tatellano ea WHO): hangata ≥10%, hangata ≥ 1 le pampitšana ea gastrointestinal: ho nyekeloa hoa pelo hoa khoneha (haholo-holo ha ho nooa moriana ka mpeng e se nang letho), gastralgia, dyspepsia, ka lipontšo tsena, ho tlosoa ha lithethefatsi ha ho hlokahale.

Ho tsoa pelong: ka seoelo - tachycardia, ho fokotseha ha khatello ea mali, sekoli sa pelo (ho kenyeletsoa le liphoso tse nang le mali reggraire) le maemo a amanang le ona (pericarditis, effusion into pericardial cavity).

Ho tsoa tsamaisong ea methapo: ka seoelo - ho tsekela, ho ruruha, hlooho e bohloko.

Ho tsoa ho sesole sa 'mele: ka seoelo - litla-morao.

Litaelo tse khethehileng

Vazobral e na le mokokotlo oa vasodilating, ntle le ho ama khatello ea mali ea systemic. Ho khethoa ha Vazobral ho bakuli ba nang le khatello ea mali ea methapo ha ho qhele ka thoko tlhoko ea ts'ebeliso ea li-antihypertgency agents. K'hafeine e fumanoang ka ho hlophisa e ka baka khathatso ea boroko, tachycardia.

Ho itima lijo ho lokela ho qojoa. Ho bakuli ba nkang dihydroergocriptine, haholo litekanyetso tse phahameng le ka nako e telele, nts'etsopele ea ho kenella ka har'a pericardial cavity le pleural cavity, hammoho le nts'etsopele ea pleural le pulmonary fibrosis le "pericarditis" e hlonephang.

Bakuli ba nang le mathata a sa hlaloseheng aururopulmonary ba lokela ho hlahlojoa le ho khaotsa kalafo ka dihydroergocriptine ho lokela ho nahanoa. Ho tlalehiloe maemo a sa tloaelehang a ho fokotswa ha fibrosis, haholo-holo ka litekanyetso tse phahameng le kalafo ea nako e telele ka dihydroergocriptine.

E le ho tseba hore na mofuta oa retrositoneal fibrosis o se o ka fetoha joang, bakuli ba joalo ba lokela ho lula ba beiloe leihlo bakeng sa matšoao a kliniki a nts'etsopele ea retroperitoneal fibrosis (bohloko ba morao, ho ruruha ha liphello tse tlase, ho se sebetse hantle ha renal. Ha ho khetholla kapa ho belaela liphetoho tsa fibrotic sebakeng sa retroperitoneal, kalafo e nang le dihydroergocriptine e lokela ho emisoa.

Baatlelete ba lokela ho lemosoa hore sethethefatsi sena se na le ntho e ka bakang karabelo e ntle litekong tse entsoeng nakong ea taolo ea doping.

Tšusumetso ho bokhoni ba ho khanna makoloi le ho etsa lintho tse ling tse ka bang kotsi. Lithethefatsi maemong a sa tloaelehang li ka baka ho fokotseha ha khatello ea mali, ho tsekela. Ha litla-morao tse joalo li etsahala, ho khanna kapa ho etsa lintho tse ling tse ka bang kotsi ho behelitsoe.

Moetsi

Chiesi Farmaceutici S.p.A. Via Palermo 26 / A, 43100 Parma, Italy Chiesi Pharmaceuticals S.p.A. Via Palermo 26 / A, 43100 Parma, Italy.

Mong'a setifikeiti sa ho ngolisa: LLC "Chiesi Pharmaceuticals", Russia, 127055, Moscow, ul. Moru, 43.

Mohala (495) 967-12-12, fax: (495) 967-12-11.

E hlophisitsoe esale pele ebile e pakiloe: Pharmstandard-Leksredstva OJSC, Russia.

Likopo tsa bareki li lokela ho romelloa atereseng: 305022, Russia, Kursk, ul. Ea bobeli Aggregate, 1a / 18,

Mohala: (4712) 34-03-13,

Matšoao a sebelisang vazobral

• fokotsa tlhokomelo
• tlhahiso e sa lekanang ea lisebelisoa tsa 'mele bakeng sa ts'ebetso e nepahetseng ea' mele le ea kelello,
• Lefu la Meniere,
• hypertonic le / kapa lefu la tsoekere,
• ho tsitsa migraines (eseng mohatong o tsoetseng pele)
• venous insuffence,
• labyrinth le vestibular mafu a,
• cerebrovascular insuffidence.

Litla-morao tse tsoang tšebelisong ea vazobral

• Ho tloha lehlakoreng la tsamaiso ea methapo e bohareng (e seng ho feta 1%): ho ruruha, bohloko hloohong, ho tsekela.
• Ho tsoa ho tsamaiso ea methapo ea pelo (eseng ho feta 0,1%): hypotension ea methapo, palpitations.
• Ho tsoa ts'ebetsong ea tšilo ea lijo (eseng ho feta 1%): dyspepsia, ho nyekeloabohloko ho epigastric.

Litaelo tsa ho sebelisa Vazobrala

Letlapa la 0,5-1 Vazobraly habeli ka letsatsi kapa 2,5 ml ea tharollo habeli ka letsatsi. Thuto e nka likhoeli tse 2-3. Haeba ho hlokahala, ho eketsoa ha thupelo ho ka etsahala ka tumellano ea ngaka e eang.

Ho khothalletsoa ho sebelisa vazobral ka lijo. Matlapa a hlatsuoa ka metsi a manyane. Tharollo e tšeloa ka metsi a fokolang, ebe e nooa ka molomo.

Litaelo tsa tšebeliso ea lithethefatsi ke bana ha li fanoe, hobane lintho tse sebetsang tse fumanehang tokisetsong ha li khothalletsoe hore li sebelisoe ke bana, haholoholo bana ba banyenyane.

Ho sebelisana le meriana e meng

Ts'ebeliso ea lithethefatsi ka lithethefatsi ho fokotsa khatello ea mali khona ho ntshetsa pele koluoa ​​ea hypotonicho fihlela ho akheha.

Ha u ntse u sebelisa mokhoa oa bongaka ka levodopa bohloko bo ka ba teng ka mpeng, ho ruruha, feberuho tsekela le ho lahleheloa ke kelello.

Hammoho le lipilisi tsa ho robala le lits'ila tse ling, Vazobral e baka ho fokolisa pilisi ea ho robala ka lebaka la hore lithethefatsi li na le psychostimulant (kofi).

Analogs Vazobrala

Ho latela sehlopha sa litlhare: Vazobral e na le li-analogues tse fetang 3 sehlopheng sa litlhare, ho kenyeletsa: Amilonosar, Bravinton, Vertisin, Ginkome, Cavinton, Nimotop, Picamolone, Stugeron, Telektol, Celllex. Li-analoggs tsa lithethefatsi ho ea tlase kapa ka tekanyo e kholo, ho latela lebitso, li bonts'a phello ea Vazobral.

Theko ea li-analogues tsa moriana li ka fapana haholo ho latela lebitso la moriana.

Ho tsamaisana le joala

Joalo ka litlhare tse ngata, ho kopanya lino tse nang le joala le Vazobral ho na le tšenyo 'meleng oa motho. E na le tokiso kofi Ha e tsoakoa le joala, e ka baka tsitsipano ea tšohanyetso, ho nyekeloa le pelo, tachycardia, ho hloka boroko le karabelo.

Lebaka la ponahalo ea litšebeliso tse mpe ke hobane "caffeine" e ntlafatsa ts'ebetso ea joala 'meleng, e potlakisa haholo le ho eketsa tahi. Ka ho hlokomoloha khafetsa le ka matla melao ea ts'ebeliso ea lithethefatsi maemong a mang, ho hlaha ha khatello ea maikutlo.

Tšebeliso ea meriana nakong ea kemolo

Bopaki bo thehiloeng ho mahlale ba mahlale mabapi le litlamorao tsa Vazobral ho fetus ha bo so hlahisoe. Tabeng ena, ha ho khothalletsoe ho sebelisa lithethefatsi nakong ea kemolo. Tabeng ea tlhokahalo e potlakileng le ka tumello ea ngaka e tšoanelehang ea kalafo e ka khona ho sebelisa Vazobral e le tharollo bakeng sa basali baimana.

Tlhahlobo mabapi le Vazobral

Litlhahlobo tse ngata tse mabapi le liforamo tikolohong ea Marang-rang li bonts'a hore lithethefatsi li ratoa haholo har'a basebelisi ba bangata bao ka kakaretso ba hlahang ba tsebahala ka moriana. Matšoao a ts'ebeliso ea lithethefatsi, haholo, ka ho se tsotelle, ho hasanya le ho tepella 'meleng / kelellong, li etsahala bongata bo boholo. Vazobral e sebetsana ka katleho le mosebetsi oa eona o ka sehloohong - ho phahamisa molumo le matla a mokuli ea tšoaroang.

Tšebeliso e sa rateheng ea vazobral ha e nkuoa ke bana. Likarabo ho tsoa ho batsoali ntlheng ena li ntle ebile li mpe. Mefuta e meng ea lithethefatsi e bontša phello e ts'oanang 'meleng oa motho, empa matšoao le matšoao a sebelisoang hangata a fapana.

Sokolla foromo le sebopeho

Vazobral e fumaneha ka mefuta e latelang ea litekanyetso:

• Round, e bataletseng lipilisi. Methapo ea koaloa. Mmala o tšoeu. Ka lehlakoreng le ka pele la pilisi ea kotsi, ka lehlakoreng le ka morao la lebitso la lithethefatsi ka Selatine (Vasobral). Ho na le matlapa a 10 ka blister. Mabili a le mong le a mararo ka paketeng.
• Meroho tsamaiso ea molomo. Tharollo: 50 di ml.

Bakeng sa letlapa le le leng la ntho e sebetsang: 40 mg kofi le 4 mg alpha dihydroergocriptine mesylate.

Bakeng sa millilita e le 'ngoe ea tharollo ea ntho e sebetsang: 1 mg ea caffeine, 1 mg ea alpha-dihydroergocriptine mesylate. Lintho tse thusang: metsi a hloekisitsoeng, ethanolcitric acid.

Litšoaneleho tsa pharmacological

Moriana o kopaneng. α-dihydroergocriptine ke ergot e tsoang ho dihydrogenated e thibelang li-receptors tsa α1 le cy2 adrenergic.

E na le dopaminergic, serotonergic effect, e fokotsa pokello ea methapo le erythrocyte, e fokotsa sekhahla sa lebota la vascular, e eketsa palo ea li-capillaries tse sebetsang, e ntlafatsa methapo ea mali le methapo ea metabolic bokong, hape e eketsa ho hanana ha lisele tsa boko ho hypoxia.

Caffeine e na le ts'ebetso ea kelello le e matlafatsang, e matlafatsang ts'ebetso ea mokokotlo mokokotlong - e eketsa ts'ebetso ea kelello le 'mele, e fokotsa mokhathala le ho otsela, e eketsa thabo ea kelello ea lesapo la mokokotlo, e thusa libaka tsa phefumoloho le tsa vasomotor, hape e na le phello ea maikutlo.

Hobaneng haobobral e laetsoe?

Ho ea ka litaelo, Vazobral ka mokhoa oa litafole le marotholi a fuoa bakuli bakeng sa kalafo le thibelo ea maemo a joalo:

• Ho hloleha ho potoloha ka sekepeng, ka lebaka la moo oksijene le limatlafatsi tse ngata tse kenang bokong (hangata boemo bona bo bakoa ke atherosclerosis e tsoelang pele),
• Ho tlosoa ha lisebelisoa tsa vestibular - ho lla le tinnitus, ho tsekela, ho se utloe litsebeng.
• Retinopathy ka lebaka la ho eketseha ho sa feleng ha khatello ea mali kapa tsoelo-pele ea lefu la tsoekere,
• Ho hloka khaello
• Lefu la Raynaud
• Nako ea ntlafatso kamora mehato ea ischemic,
• Lefu la Meniere,
• Ho fokotseha ha nako, ho tepella le ho senyeha ha mohopolo ka lebaka la ho se lekane ha oksijene le glucose bokong.

Setlhare sena se boetse se fuoe mokuli e le kalafo ea prophylactic ea litlhaselo tsa migraine.

Taeo ea bongaka bakeng sa tšebeliso

Vazobral e nooa habeli ka letsatsi bakeng sa matlapa a 0.5-1 kapa a 2-4 ml ea tharollo. Thuto e nka likhoeli tse 2-3. Haeba ho hlokahala, ho eketsoa ha thupelo ho ka etsahala ka tumellano ea ngaka e eang.

Ho khothalletsoa ho sebelisa vazobral ka lijo. Matlapa a hlatsuoa ka metsi a manyane. Tharollo e tšeloa ka metsi a fokolang, ebe e nooa ka molomo.

Contraindication

• Hypersensitivity ho likarolo tse sebetsang tsa lithethefatsi.
• Nakong ea bokhachane (ho tloha ka mor'a moo phello ea lesea la moriana le polokeho ea lona ha e so fumanoe).
• Ka tlhokomeliso ha ho anyesa (ho na le bopaki ba hore moriana o lebisa ho fokotseha tlhahiso ea lebese la matsoele).

Litla-morao le ho sebelisa overdose haholo

Ha e le molao, Vazobral ea lithethefatsi e mamelloa hantle ke bakuli ba bangata. Leha ho le joalo, joalo ka moriana o mong le o mong, o ka baka tšusumetso e mpe ea 'mele. Karolo ea bohlokoa ea karabelo e mpe e etsahala haholo ho bakuli ba nang le hypersensitivity ea 'mele.

Litla-morao li bonahala ka mokhoa oa tlolo ea litsamaiso le litho tse ling tsa ka hare:

• Mathata a ts'oaetso ea mokokotlo: ho nyekeloa pelo (ho bontšoa haholo ha ho sebelisoa lithethefatsi ka mpeng e se nang letho), gastralgia, le tshiloetso e thata. Matšoao a mangata a ikela ka boeona, ha a lokela ho khaoloa.
• Ho tsoa ho CCC: maemong a sa tloaelehang - tachycardia, ho fokotseha ha khatello ea mali, bofokoli ba mesifa ea pelo (ho kenyelletsa le pathology le regurgitation (reverse hona joale) ea mali) le maemo a amanang le ona (ho ruruha ha membrane ea serous ea pelo, ho kenella ka har'a pericardium).
• NS: ho bakuli ba bang - ho tsekela, ho ferekana kelellong, hlooho e bohloko.
• Sistimi ea 'mele ea mafu a tšoaetsanoang: ho bakuli ba amehang haholo, liponahatso tsa mafu.

Haeba matšoao ana kapa a mang a sa rateheng a hlaha, o lokela ho ikopanya le ngaka ea hau ea kalafo bakeng sa tšebeliso ea mofuta oa kalafo.

Ho nka litekanyetso tse kholo haholo tsa Vazobral ho ka baka khatello ea mmele o mangata ka sethethefatsi. E iponahatsa ka mokhoa oa litla-morao tse eketsehang.

Ho felisa tšebeliso e feteletseng, ho nkuoa mehato ea ho hloekisa setopo sa masala a litlhare, kalafo ea matšoao e laetsoe.

Sebelisa nakong ea bokhachane le pelehi

Ka bongaka, ha ho na data e nepahetseng mabapi le polokeho ea litlamorao tsa likarolo tsa moriana ho lesea, kahoo ka nako ea pele ea kemaro, matlapa a Vazobral ha a fuoe kalafo ho basali.

Karolong ea bobeli le ea boraro, kalafo e nang le pheko ena e ka etsahala maemong ao phaello e lebelletsoeng ho mme ea lebelletsoeng e tla ba kholo ho feta kotsi e ka hlahang ho lesea. Mosali ea noang sethethefatsi sena o lokela ho ba tlas'a taolo ea ngaka kamehla le nts'etsopele ea matšoao a mabe kapa litla-morao, a hlakola kalafo.

Ts'ebeliso ea Vazobral nakong ea ho anyesa ho latela lithuto e lebisitse ho fokotseheng hanyane ha tlhahiso ea lebese la matsoele ho basali.

U ka nka bana joang?

Litaelo tsa tšebeliso ha li fuoe bana hore ba noe moriana, hobane lintho tse sebetsang tse fumanehang tokisetsong ha li khothalletsoe hore li sebelisoe ke bana, haholoholo bana ba banyenyane.

Liphetoho tsa likotsi tsa cerebrovascular li kenyelletsa analogane:

1. Amilonosar,
2. Bilobil
3. Bilobil Forte
4. Bravinton
5. Sefuba
6. Vero Vinpocetine,
7. Vertisin
8. Vertisin Forte,
9. Winkamine
10. Winpoton
11. Vinpocetine,
12. Vinpocetine forte,
13. Vincetin
14. Vitrum Memori,
15. Gingium
16. Ginkgo Biloba,
17. Ginkio
18. Ginkome,
19. Ginos
20. Dilceren
21. Cavinton
22. Cavinton forte
23. Khaello
24. Xanthinol Nicotinate,
25. Nilogrin
26. Nimopin
27. Nimotop,
28. Nicergoline,
29. Oxebral
30. Picamilon
31. Picanoyl
32. Pikogam
33. Sermion,
34. Stugeron
35. Tanakan
36. Telektol,
37. Celllex
38. Cinedil
39. Cinnarizine,
40. Cinnaron
41. Cinnasan.

Ha u khetha li-analogues, ho lokela ho hopoloa hore litaelo tsa tšebeliso ea Vazobral, theko le litekanyetso tsa lithethefatsi tse nang le litlamorao tse tšoanang ha li sebetse. Phetoho ea moriana e ka lumelloa feela ka mor'a khothaletso ea ngaka.

Vazobral ka joala

Joalo ka litlhare tse ngata, ho kopanya lino tse nang le joala le Vazobral ho na le tšenyo 'meleng oa motho. E na le tokiso kofiHa e tsoakoa le joala, e ka baka tsitsipano ea tšohanyetso, ho nyekeloa le pelo, tachycardia, ho hloka boroko le karabelo.

Lebaka la ponahalo ea litšebeliso tse mpe ke hobane "caffeine" e ntlafatsa ts'ebetso ea joala 'meleng, e potlakisa haholo le ho eketsa tahi. Ka ho hlokomoloha khafetsa le ka matla melao ea ts'ebeliso ea lithethefatsi maemong a mang, ho hlaha ha khatello ea maikutlo.

Ho sebelisana le lithethefatsi

Nakong ea Vasobral, ho lokela ho hopoloa hore lithethefatsi ha li ratehe ho kopantsoe le meriana ka matla a antihypertensive, hobane motsoako o joalo o ka baka phello le phello ea khatello ea methapo ea kutlo.

Matlapa a Vazobral ha a ratehe ho a nka ka nako e le 'ngoe le lipilisi tsa ho robala le li-narcotic painkillers, kaha k'hafeine e fumanehang matlapeng e fokotsa matla a eona a ho hlohlona le ho hlohlona.

Ho khothalletsoa ho hana tšebeliso e kopaneng ea lithethefatsi ka lithethefatsi tse nang levodopa, kaha ho sebelisana ha lintho tse fapaneng ho baka ho ba teng ha bohloko ka mpeng, nts'etsopele ea feberu, ho ruruha, hlooho e bohloko. Hape, tahlehelo ea kelello ha e khetholloe.

Litlhahlobo li bua ka eng?

Litlhahlobo tse ngata li bonts'a hore lithethefatsi li ratoa haholo har'a basebelisi ba bangata, bao ka kakaretso ba hlahang ka lithethefatsi. Matšoao a ts'ebeliso ea lithethefatsi, haholoholo, ka ho se tsotelle, ho sitisoa le ho tepella 'meleng / kelellong, li hlaha bathong ba bangata. Vazobral e sebetsana ka katleho le mosebetsi oa eona o ka sehloohong - ho phahamisa molumo le matla a mokuli ea tšoaroang.

Tšebeliso e sa rateheng ea vazobral ha e nkuoa ke bana. Likarabo ho tsoa ho batsoali ntlheng ena li ntle ebile li mpe.