Ke khale lithibela-mafu li kenelletse ka matla bophelong ba motho. Joale o ka fumana lithethefatsi tse thibelang likokoana-hloko, sesepa sa antibacterial, gel ea bactericidal kapa wipes, joalo-joalo. Empa sebelisa mekhoa eohle ka hloko haholo. Haholo-holo ha ho tluoa meriana. Sengoloa sa kajeno se tla u bolella hore na Gentamicin-Akos ke eng. Bakeng sa seo setlolo se sebelisoang, 'me maemong ao ho leng molemo ho se hana, o tla ithuta ho ea pele.

Mofumahali

Kamora ts'ebeliso, sehlahisoa se batla se sa anngoe kantle. Moriana o sebetsa hang-hang sebakeng sa ho ruruha kapa leqeba.

Kamora ho tsamaiso ka intramuscularly, ntho e sebetsang e kenella ka potlako. Excretion e teng ka moroto le bile. E tlama liprotheine tsa mali tsa plasma hanyane.

Ho monya marotholi a mahlo ho ka tšoantšoa le ho se bohlokoa.

Contraindication

Mafura ha a khothalletsoe molemong oa kalafo haeba motho a e-na le kutloisiso e eketsehileng ea karolo ea lithethefatsi (ho kenyelletsa le nalane) kapa aminoglycosides, uremia, leqhubu la methapo ea kutlo.

Gentamicin Akos e sebelisoa kalafo ea likokoana-hloko tsa mahlo tsa baktheria.

Mofumahali

E hokahana le mookotaba oa 30S oa ribosomes mme e senya synthetiki, e thibela sebopeho sa moralo oa lipalangwang le morongwa RNA, mme khoutu ea liphatsa tsa lefutso e baloa ka phoso mme liprotheine tse sa sebetseng li thehiloe. Maemong a tebileng, e senya mosebetsi oa tšireletso ea membrane ea cytoplasmic mme e baka lefu la likokoana-hloko.

E sebetsa hantle khahlanong le libaktheria tse ngata tse ntle tsa gram le gram-negative. Likokoana-hloko tse se nang tšoaetso ea Gram - Proteus spp li na le kutloelo-bohloko haholo ho li-glamicin (MPC ka tlase ho 4 mg / l). (ho kenyeletsoa likarolo tsa indole-tse ntle le tse seng ntle le tse mpe), Escherichia coli, Klebsiella spp., Salmonella spp., Shigella spp., Campylobacter spp. (ho kenyeletsoa ho thibela-penicillin), e qenehelang le MPC 4-8 mg / l - Serratia spp., Klebsiella spp., Pseudomonas spp. (ho kenyeletsoa Pseudomonas aeruginosa), Acinetobacter spp., Citrobacter spp., Providencia spp. Ho hanyetsa (MPC ho feta 8 mg / l) - Neisseria meningitidis, Treponema pallidum, Streptococcus spp. (ho kenyelletsa le Streptococcus pneumoniae le lihlopha tsa sehlopha D), Bacteroides spp., Clostridium spp., Providencia rettgeri. Hammoho le penicillin (ho kenyelletsa benzylpenicillin, ampicillin, carbenicillin, oxacillin), e sebetsang ka mokhoa o hlophisitsoeng oa lebota la lisele tsa likokoana-hloko, e sebetsa khahlanong le Enterococcus faecalis, Enterococcus faecium, Enterococcus durans, Enterococcus faiumium le hoo e ka bang tsohle tsa Streptococs mefuta e fapaneng (ho kenyelletsa le mefuta ea Streptococcus faecalis liguifaciens, Streptococcus faecalis zymogene), Streptococcus faecium, Streptococcus durans. Ho hanyetsa ha likokoana-hloko tse tsamaeang le 'mele butle-butle ho fetoha butle, leha ho le joalo, mathata a hanyetsanang le neomycin le kanamycin a ka boela a bontša ho hanyetsa ka bonolo (leano le sa felletseng la khang). Ha e ame anaerobes, li-fungus, livaerase, protozoa.

Bongata

Matšoao: ho fokotseha ha methapo ea methapo (ho ts'oara moea).

Phekolo: Lithethefatsi tse khahlanong le cholinesterase (Proserinum) le litokisetso tsa calcium (5-10 ml ea tharollo ea 10% ea calcium chloride, 5-10 ml ea tharollo ea 10% ea calcium gluconate) li hlahisoa ho batho ba baholo. Pele ho kenyelletsoa Prozerin, atropine ka tekanyetso ea 0.5-0.7 mg e tsamaisoa ka mokhoa oa mofuta oa iv, ho lebeletsoe ho eketseha ha pelo, mme 1.5-2 metsotso hamorao, 1.5 mg (3 ml ea tharollo ea 0,05%) ea Prozerin e kenngoe. Haeba phello ea lethal dose lena e ne e sa lekana, tekanyo e le 'ngoe ea Prozerin e ts'oaroa hape (ka ponahalo ea bradycardia, ho fanoa ka ente e' ngoe ea atropine). Bana ba fuoa limatlafatsi tsa calcium. Maemong a tebileng a khatello ea maikutlo a ho hema, ho hlokahala moea o lekaneng oa mochini. E ka ts'oaroa ke hemodialysis (e sebetsang haholoanyane) le peritoneal dialysis.