Ke eng e thusang amitriptyline matlapeng: litaelo tsa tšebeliso

Amitriptyline
Khemik'hale ea lik'hemik'hale
IUPAC5- (3-Dimethylaminopropylidene) -10,11-dihydrodibenzocycloheptene
Foromo e akaretsangC20H23N
Boima ba Molar277,403 g / mol
Cas50-48-6
PubChem2160
DrugbankAPRD00227
Tlhomamiso
ATXN06AA09
Mofumahali
Bioavava30—60 %
MetabolismSebete
Half-life.10-26 h
MofutaLiphio
Mefuta ea Litekanyetso
matlapa (dragees) 10, 25, 50, 75 mg, khutlisetsa likhalase tsa 50 mg, 1% tharollo ho ampoules, 2 ml.
Tsela ea tsamaiso
ka hare, ka methapo, methapo (Drip)
Mabitso a mang
Amitriptyline, Amizol, Amirol, Saroten Retard, Triptisol, Elivel, Amineurin, Apo-Amitriptyline, Novo-Triptin, Adepren
Wikimedia Commons Media Lifaele

Amitriptyline (lat. Amitriptylinum) - e mong oa baemeli ba ka sehloohong ba li-antidepressants tsa li-tricyclic, hammoho le imipramine le clomipramine. Amitriptyline ke lithethefatsi tse sebelisetsoang ho phekola maloetse a mangata a kelello: khatello ea maikutlo le khatello ea maikutlo, e sa atiseng ho ba teng kamehla. Matšoao a mang a kenyelletsa migraine prophylaxis, kalafo ea bohloko ba neuropathic joalo ka fibromyalgia le postherpetic neuralgia, le ho hloka boroko ho sa tloaelehang. Setlhare ke sa sehlopha sa li-antidepressants tsa li-tricyclic (TCAs), 'me mohato oa ts'ebetso ha o hlake hantle. Amitriptyline e tsamaisoa ka molomo hape e le ente.

Litlamorao tse kholo li kenyelletsa pono e sa boneng, molomo o omileng, khatello e tlase ea mali ha o eme, ho otsela le ho sokela. Litla-morao tse matla li ka kenyelletsa ho tsitsipana, kotsi e eketsehang ea ho ipolaea ho batho ba ka tlase ho lilemo tse 25, ho bolokoa ka moroto, glaucoma le mathata a mangata a pelo. Amitriptyline ha ea lokela ho nkuoa le li-inhibitors tsa MAO kapa le cosapride ea lithethefatsi. Amitriptyline e ka baka mathata haeba e nkuoa nakong ea kemaro. Sebelisa nakong ea kanyeso ho bonahala ho bolokehile.

Amitriptyline e fumanoe ka 1960 mme ea amoheloa ke U.S. Food and Drug Administration (FDA) ka 1961. E fumaneha joalo ka mori oa generic.

Phello ea Timoanaleptic (antidepressant) e kopantsoe le phello e boletsoeng ea ho susumetsa kelello, hypnotic le anxiolytic (anti-matšoenyeho) ka lebaka la ketsahalo e matla ea anticholinergic le antihistamine. Hajoale, amitriptyline e nkoa e tšepahala ka ho fetisisa. mohloli? le antidepressant e theko e tlaase haholo. E kenyelelitsoe lethathamong la meriana e khothalletsoang ke Mokhatlo oa Lefatše oa Bophelo.

Ts'ebeliso ea bongaka

Ke inhibitor ea neuronal reuptake ea mediator monoamines, ho kenyelletsa norepinephrine, dopamine, serotonin, jj. Ha e bake tšitiso ea MAO.

Bohlokoa ba M-cholinolytic (anticholinergic), antihistamine, le ts'ebetso ea alpha-adrenolytic ke tšobotsi. Le ha ho le joalo, amitriptyline ha e na botlalo ba phello e matlafatsang, e matlafatsang kelello. Tšusumetso e susumetsang e phatlalatsoa ka ho khetheha lethathamong le itseng la litekanyetso (bakeng sa mokuli ka mong, nako ena ke motho ka mong) mme karolo e 'ngoe e amana le keketseho ea khatello ea metabolite ea mantlha e sebetsang ea amitriptyline, nortriptyline, ka polelo e khothatsang le e matlafatsang kelello, ka karolo e itseng le phello ea matla e matlafatsang le e matlafatsang ka boeona. Ha tekanyo e kaholimo ea "fensetere" ena ea litekanyetso e fetisoa, matla a susumetsang a amitriptyline a qala ho ba matla, 'me phello e bonahatsang (ebile ka linako tse ling ea antidepressant) ea fokola. Bakeng sa litekanyetso tse tlase, ka tlase ho monyako o mong oa "antidepressant", ha ho lits'oants'o tse tsosang takatso kapa tse khahlanong le khatello ea maikutlo li ka bonoang - litheko tse seng feela tse qaqileng, khatello ea maikutlo le khatello ea khatello.

Ka matla a phello ea sedative, hypnotic le anti-matšoafo, amitriptyline sehlopheng sa li-tricyclics e theotsoe feela ho trimipramine le fluoroacisin, mme ka matla a phello e tsosang le ea psychoenergetic e tlaasana le clomipramine, imipramine le tricyclics ea subgrouprorttyort, nortriportrort. Ka mantsoe a mang, amitriptyline e haufi le pheletso ea "fantisi" ea li-tricyclics, empa eseng qetellong ea sebono.

Kopo ho editeng ea meriana |Fomu ea tokollo

Ho na le mefuta e 'meli ea tokollo ea lithethefatsi - matlapa le tharollo bakeng sa tsamaiso ea batsoali. Ho na le matlapa a nang le litekanyetso tsa 10, 25 le 50 mg. 1 ml ea tharollo e na le 10 mg ea amitriptyline. Setlhare se fanoa feela ka taelo ea ngaka.

Li-analog tsa li-amitriptyline ke:

Ntle le moo, ho na le lithethefatsi tse ling tse loantšang khatello ea maikutlo. Sehlopha sa li-antidepressants tsa tricyclic se boetse se kenyeletsa imipramine le clomipramine. Leha ho le joalo, ehlile, ho khetha pheko e nepahetseng khahlanong le khatello ea maikutlo ke tokelo ea ngaka ea kelello, psychologist kapa neuropathologist, 'me phekolo ea meriana ha e ea nepahala ebile e kotsi mona.

Contraindication

Amitriptyline e hanyetsitsoe ho:

  • mefuta e matla ea pelo le ho hloleha ha liphi,
  • Bofokoli ba pelo bo senyehileng,
  • khatello e matla ea mali,
  • acute kapa subacute mefuta ea myocardial infarction,
  • ho tahoa haholo ke joala, lipilisi tsa ho robala, analgesics le lintho tse fanang ka kelello.
  • angle-shutter glaucoma,
  • atrioventricular block 2 tbsp;
  • ka tlase ho lilemo tse 6
  • ha o ntse o nka li-inhibitors tsa MAO.

Nakong ea kemolo, ho sebelisa moriana ho ka hlalosoa feela ho sa na le mofuta o mong, ka mor'a hore ngaka e lekole melemo le mathata. Joalokaha ho bontšoa ka liteko tsa liphoofolo, lithethefatsi li na le phello ea teratogenic. Masea a sa tsoa tsoaloa a basali ba noang moriana nakong ea kemolo a ka ba le bothata ba ho otsela kapa ho lla ka nako e itseng. Hape, sethethefatsi ha se lumelloe nakong ea lactation ka lebaka la bokhoni ba eona ba ho kenella ka lebeseng la matsoele. Bana ba bo-mme ba anyesang ba nkang amitriptyline le bona ba ka ba le bothata ba ho otsela ho eketsehileng.

Kahare, lithethefatsi li kenyelelitsoe batho ba khannang likoloi le ho etsa mosebetsi o hlokang ho tsepamisa maikutlo.

Lithethefatsi li fanoa ka hloko ho:

  • Mathata a amanang le lefu la pelo (haholo-holo lefu la pelo, corharymias, ho nyekeloa ke pelo),
  • joala bo sa feleng
  • asthma ea lefu la bronchial,
  • ho fokotseha ha koloi sebetsa,
  • nalane ea matšoao a kholisang,
  • manic-depress psychoses,
  • maqeba
  • renal le hepatic pathologies,
  • ts'ebetso ea urine le hypotension ea senya,
  • thyrotooticosis,
  • lefu la sethoathoa
  • Prostatic hyperplasia.

Phekolo ea bakuli ba nang le khatello ea maikutlo e tebileng le lefu le kotsing ea ho ipolaea e lokela ho etsoa feela sepetlele.

Litlamorao

Litlamorao tse sa tloaelehang tse bang teng ka lebaka la ho sebelisa moriana li kenyeletsa:

  • ho otsela kapa ho hloka boroko,
  • hlooho e bohloko
  • ho tsekela
  • karohano ea mmele (letlalo - urticaria, rash kapa ho hlohlona, ​​kapa systemic - ho ts'oaroa hoa anaphylactic, edema ea Quincke),
  • bohloko ba ka mpeng, ho nyekeloa, lets'ollo, ho sokela,
  • e tlola khatello ea mali (hangata khatello ea maikutlo, ka lebaka la lithethefatsi tse thibelang alpha),
  • khatello ea metsi ha e ema kapa e tlosa 'mele ho tloha leshanong ho ea sebakeng sa ho lula (hypthension orthostatic hypotension),
  • arrhythmias
  • khatello e eketsehileng ea intraocular.

Maemong a boroko, tšebeliso ea amitriptyline ho litekanyetso tse kaholimo ho 150 mg ka letsatsi e ka baka ho theoha ha monyako oa ho ts'oaroa. Ha e sebelisoa ho bana le ho bacha ba ho fihlela lilemo tse 24, e ka eketsa kotsi ea boitšoaro ba ho ipolaea. Ts'ebeliso ea nako e telele e eketsa menyetla ea caries.

Ho tloha lehlakoreng la tsamaiso ea methapo e bohareng le eona e ka bonoa:

  • ho akheha
  • tinnitus
  • eketseha ho teneha
  • pherekano
  • ho tšoenyeha
  • hallucinations
  • ntshetsopele ea mania,
  • ho senyeha hoa mohopolo
  • ho tšoenyeha ka koloi
  • ho tsitsipana ho eketsehileng,
  • phoebe ea sethoathoa,
  • extrapyramidal mafu a,
  • ho fokotsa matla a ho tsepamisa mohopolo,
  • bosiu.

Liphetoho li tsebahala ho batho ba tsofetseng le bakuli ba nang le lefu la Parkinson.

Ponahalo ea lefu la sethoathoa o ts'oaroa hangata ho iponahatsa ha o sebelisa moriana o tekanyetso e phahameng, ho bakuli ba nang le lefu la ho akheha kapa ho bakuli ba nang le nalane ea ho sithabela maikutlong. Maemong a joalo, ho lokisoa tekanyetso kapa tsamaiso ea li-anticonvulsants hoa hlokahala.

Ho tsoa ho tsamaiso ea pelo le pelo le tsona lia khoneha:

  • lefu la pelo le amanang le pelo,
  • liphetoho lipakeng tsa QT ho ECG (e hloka ho fokotsa tekanyetso kapa ho lekola paramente ka linako tsohle),
  • tachycardia
  • palpitations.

Litla-morao tse hlahisoang ke ketso ea anticholinergic:

  • molomo o omileng
  • malinyane a hlapollotsoeng
  • tlolo ea bolulo (pono e fifalitsoeng),
  • ho bolokoa ka moroto
  • bokhoba ba ho ipolaisa tlala
  • Ho thijoa ke mala (haholoholo ho batho ba tsofetseng le ho bakuli ba nang le tloaelo ea ho sokela).

Ho tsoa ho mokhoa oa tšilo oa lijo le ona oa khonahala:

  • nts'etsopele ea hepatitis le jaundice,
  • pelo e bohloko
  • takatso e matla ea lijo (hangata e le lithethefatsi, ka lehlakoreng le leng, e lebisa ho fokotseha ha takatso ea lijo),

Ho tsoa tsamaisong ea endocrine, liketsahalo tse latelang li ka etsahala:

  • testema tsa edema,
  • gynecomastia (ho holisa matsoele, ho basali le banna),
  • fokotseha kapa ho eketsa libido,
  • fetoha ha potency.

Litlamorao tse latelang ha li khethoe:

  • tahlehelo ea moriri
  • stomatitis
  • ho fifatsa leleme,
  • ho ruruha
  • ho ruruha ha li-lymph node
  • ho thothomela ka letsoho (ho amanang le ho hlohlelletsa sistimi ea beta-adrenergic, e ntlafalitsoeng ka ho nka beta-blockers),
  • liphetoho phetohong ea mali (leukopenia, eosinophilia, thrombocytopenia), phallo ea glucose maling.

Ha o khaotsa ho sebelisa lithethefatsi, ho ka etsahala lintho tse latelang:

  • hlooho e bohloko
  • nyakallo
  • kakaretso malaise
  • lets'ollo
  • ho tšoenyeha ka koloi
  • ho se khonehe.

Ka hona, pele o khaotsa ho sebelisa moriana, ho bohlokoa ho fokotsa tekanyetso butle-butle. Hangata matšoao ana ke a nakoana ebile ha se bopaki ba ho ts'epahala ha lithethefatsi.

Litaelo tsa ho sebelisoa

Tekanyetso ea pele matlapeng ke 25-50 mg (matlapa a 1-2 a 25 mg) ka letsatsi. Tabeng ena, lithethefatsi li khethoa pele ho nako ea ho robala. Ebe joale butle-butle tekanyetso e eketseha (letsatsi le letsatsi 25 mg) ho ea ho 150-200 mg. Tabeng ena, tekanyetso ea letsatsi le letsatsi e lokela ho aroloa ka tekanyetso e meraro. Palo e kholo ea lithethefatsi e lokela ho nooa bosiu.

Maemong a bonolo, ho bakuli ba noang moriana ka lekhetlo la pele, ho bakuli ba nang le mafu a matla a sa foleng, ho batho ba baholo kapa ba lilemong tsa bocha, ho khothalletsoa tekanyo e potlakileng ea tekanyetso ea 25 (25 mg ka matsatsi a 2-3). Khatellong e matla, e kotsi ea ho ipolaea, ho fapana le hoo, o lokela ho qala hang-hang ka litekanyetso tse kholo tsa letsatsi le letsatsi (100 mg).

Tekanyetso e kholo ea letsatsi le letsatsi bakeng sa kalafo ea ntle ke 200 mg, bakeng sa kalafo ea nakong e tlang - 300 mg. Maemong a mang, ka khatello ea maikutlo e matla le mamello e ntle ho lithethefatsi, ho ka khonahala ho eketsa tekanyetso e phahameng ea letsatsi le letsatsi ho 400-450 g.

Ho bulimia amanosa, mathata a maikutlo, schizophrenia, e imetsoeng ke psychosis, ho itlopa joala ho qala ka lethal dose ea 25-100 mg (litafole tsa 25 mg) bosiu. Kamora ho fihlela phello ea kalafo, ho hlokahala hore o fetole lethal dose e sebetsang e tlase - 10-50 mg ka letsatsi.

Thibelo ea migraine, bohloko bo sa foleng ba neurogenic, li-ulcer tsa gastrointestinal li hloka tekanyetso ea letsatsi le letsatsi ea 10-100 mg (lethal dose le laetsoe ke ngaka ho latela maemo a itseng). Ho feta moo, boholo ba lethal dose bo nooa bosiu.

Molemong oa kalafo ea maemo a sithabetsang ho bana ba lilemo li 6-12, ho hlokahala hore o noe moriana o 10-30 mg ka letsatsi. Kapa o ka bala litekanyetso ho latela boima ba 1.5 mg / kg.

Ka li-enisis tsa bosiu ho bana ba lilemo li 6-12, ho fanoa ka 10 mg, hangata hangata ke 20 mg. Bana ba kaholimo ho lilemo tse 12 - ho fihlela ho 50 mg. Setlhare se nooa hanngoe bosiu.

Nako ea kalafo e latela lintlha tse ngata - boemo ba mokuli, mofuta oa bokuli, mme bo ka fapana ho tloha likhoeli tse 'maloa ho isa selemong se le seng.

Bakeng sa ts'ebetso ea renal e sa sebetseng hantle, ho hlokahala tokiso ea tekanyetso. Phetoho ea moriana e boetse e hlokahala bakeng sa ba tsofetseng.

Ho qoba ho hlaha hampe, moriana o lokela ho nooa hang hoba o je.

Ka ho tlosoa ha moriana ka thata, ho ka hlaha letšoao la ho intša. Ka hona, ho khothalletsoa ho fokotsa butle-butle litekanyetso tsa moriana pele lefu le fela.

Bongata

Haeba ho na le overdose, ho ka etsahala lintho tse latelang:

  • stupor
  • ho otsela ho eketsehileng
  • coma
  • nyakallo
  • pherekano,
  • pherekano
  • ho hlatsa
  • khatello ea maikutlo
  • tachycardia
  • khatello ea khatello
  • arrhythmias
  • ho hema hanyane.

Ho hlokahala sefuba, kalafo ea matšoao. Hemodialysis ha e na thuso.

Ho sebelisana le lintho tse ling

Setlhare sena ha se lumellane le joala. Ka hona, nakong ea phekolo, ho hlokahala hore u tlohele joala. Ha ua lokela ho nka sethethefatsi sena ka li-antidepressants tse ling. Ts'ebeliso ea sehlopha sa li-inhibitors tsa serotonin tse khethiloeng ka li-antidepressants li ka lebisa ho serotonin syndrome.

Ha e lumellane ka botlalo le sehlopha se seng sa li-antidepressants - li-inhibitors tsa MAO. Ka tšebeliso e ts'oanang le li-inhibitors tsa MAO, ho tsitsipana ho matla le likotsi tsa khatello ea mali tse matla li ka ba teng, tseo hangata li qetellang lefung la mokuli. Ka hona, karohano lipakeng tsa lithuto tsa kalafo le amitriptyline le MAO inhibitors e lokela ho ba bonyane libeke tse 2.

Ka tsamaiso e tšoanang ka li-benzodiazepines, ntlafatso e lumellanang ea phello ea kalafo e ka bonoa. Ha o sebelisoa le li-antidepressants tse ling, barbiturates, sedatives, benzodiazepines, anesthetics e akaretsang, phello ea inhibitory tsamaisong ea methapo ea methapo e eketseha, ho hlaha phello ea hypotensive, khatello ea maikutlo ea ho hema.

Amitriptyline e boetse e ntlafatsa sephetho tsamaisong ea pelo le epinephrine, ephedrine, joalo-joalo, e bakang kotsi ea tachycardia, arrhythmias le arterial hypertension. Ka hona, ha ho etsoa anesthesia (anesthetics hangata e kenyelletsa epinephrine), ngaka e lokela ho tsebisoa ka mokuli ea nkang sethethefatsi sena sa antidepressant e le hore a fetole lethalinyana la lithibela-mafu.

E eketsa phello ea kalafo ea li-anticholinergic, li-antihistamines, tse ka lebisang litlamorao tse eketsehileng. Amantadine e eketsa phello ea anticholinergic.

Setlhare se fokotsa ts'ebetso ea li-alpha-blockers, li-anticonvulsants le lithethefatsi tse antihypertensive. Clonidine le li-antihistamine li eketsa phello ea inhibitory tsamaisong ea methapo ea kutlo, atropine e eketsa kotsi ea ho holofala ea mala. Ka nako e ts'oanang, clonidine le methyldopa li fokotsa phello ea hypotensive.

Bakuli, nicotine e fokotsa katleho ea sethethefatsi. Cocaine e eketsa kotsi ea arrhythmias. Li-adrenomimetics tsa lehae li eketsa phello ea vasoconstrictor. Ts'ebeliso ea lihormone tsa qoqotho e nang le lithethefatsi e eketsa litla-morao tsa bobeli tsa kalafo le litlamorao.

Tlhaloso ea litaelo bakeng sa tšebeliso ea amitriptyline

Amitriptyline ke lithethefatsi tse tsoang sehlopheng sa li-antidepressants tsa li-tricyclic. Ntle le litlamorao tse kholo, e na le phello ea li-analgesic, e thusa kalafo ea ho robala.

Amitriptyline e hlahisoa ke baetsi ba 'maloa - Veropharm ea malapeng, ALSI Pharma, hammoho le ba kantle ho naha - Grindex, Nycomed, tlasa mabitso a fapaneng a khoebo:

Amitriptyline ke ea sehlopha sa litlhare tsa litlhare tse thibelang mafu. Foromo ea eona e kholo ke: C20H23N.Lebitso la Machaba le sa Ts'oanelehe (INN) ke amitriptyline.

Lokolla liforomo le sebopeho

Amitriptyline e fumaneha ka mefuta e 'meli ea litekanyetso - matlapa le tharollo.

  1. Matlapa a 10 le 25 mg bakeng sa tšebeliso ea kahare. Likotoana tse 50 le 100 li kentsoe ka har'a mekotla ea li-contour.
  2. Tharollo ea 10 mg / ml, ampoules ea 2 ml bakeng sa tsamaiso ea methapo le methapo. Ka har'a pakete ea likotoana tse 10.

Matlapa a na le 10 kapa 25 mg ea ntho e sebetsang - amitriptyline hydrochloride. Lintho tse eketsehileng (tse sa sebetseng) ke li-cellcose tsa microcrystalline, talc, lactose monohydrate, silicon dioxide, magnesium stearate, stgelatinized stark.

Sebopeho sa moriana "Amitriptyline" ka sebopeho sa tharollo se kenyelletsa 10 mg ea ntho e sebetsang mme ka ho eketsa - hydrochloric (hydrochloric) acid, benzetonium le sodium chloride, dextrose monohydrate, metsi bakeng sa infusion.

Ketso ea pharmacological

Setlhare ke sa litlhare tse matlafatsang. Mochine oa ts'ebetso ea amitriptyline 'meleng ke keketseho ea khatello ea norepinephrine ho li-synapses le serotonin tsamaisong ea methapo ea methapo (ho amoheloa ha bona ka morao ho fokotseha). Ka kalafo ea nako e telele, tšebetso e sebetsang ea beta-2 adrenergic hammoho le li-receptor tsa serotonin bokong lia fokotseha. E na le phello ea anticholinergic athari (e bohareng le e poteletseng).

Amitriptyline e sebetsa joang maemong a sithabetsang? - e ntlafatsa ho feto-fetoha ha maikutlo, e fokotsa ho ferekana kelellong, ho tšoenyeha, ho robala boroko. Litlamorao tsa lithethefatsi li iponahatsa libeke tse 2-3 kamora ho qala taolo.

Ntle le phello e boletsoeng e felisang khatello ea maikutlo, lithethefatsi li na le liketso tse ling tse 'maloa.

  1. Antiulcer e amanang le ho thibeloa ha li-histamine receptors tsamaisong ea tšilo ea lijo.
  2. Ho fokotse takatso ea lijo.
  3. Ho eketsa bokhoni ba bladder ea ho otlolla le ho eketsa molumo oa sphincter, e thehiloeng ho fokotseha hoa ts'ebetso ea li-receptors tsa serotonin le acetylcholine.
  4. Haeba anesthesia e akaretsang e reriloe, joale ho hlokahala hore ho lemose ngaka ka ho nka moriana ona, kaha o fokotsa boemo ba khatello ea mali le mocheso oa 'mele.
  5. E felisa bohloko. Amitriptyline e qala ho thusa ka bohloko neng? - ho latela tlhahlobo ea bakuli, e se e ntse e le ka matsatsi a 2-3 a kalafo.
  6. E khaola ho robala.

Matšoao a ho sebelisoa

Lethathamo la lipontšo le atile, empa lebaka le ka sehloohong la ho khethoa ha amitriptyline ke maemo a sithabetsang a tsoang litsong tse fapaneng.

Ke eng e thusang amitriptyline?

  1. Ho sithabela maikutlo - ho sa sebelisoe, ho emisa, ho ruruha, ho ba le ts'ebetso, lithethefatsi, khahlano le semelo sa ho tlosa joala, ts'enyo ea ts'ebetso ea boko. Haholo-holo e etsahala ka matšoenyeho, likhathatso tsa boroko.
  2. Mathata a maikutlo a tlhaho e tsoakiloeng. Amitriptyline e ka laeloa bakeng sa tlhaselo ea letsoalo.
  3. Psychoses ka morao ho schizophrenia, ho itlopa joala.
  4. Mathata a boitšoaro (liphetoho tlhokomelong le tšebetsong).
  5. Enuresis bosiu.
  6. Lefu la bohloko bo sa foleng - mafu a oncological, rheumatic, neuralgia ea morao-rao, bohloko ba morao-morao.
  7. Bulimia amanosa.
  8. Thibelo ea Migraine
  9. Lcerative ulcerative ea tsamaiso ea tšilo ea lijo.

Matšoao a ts'ebeliso ea litafole le tharollo ea Amitriptyline lia tšoana.

Ts'ebeliso ea matlapa

Na o hloka ho noa amitriptyline pele kapa ka mor'a lijo? Matlapa a nooa ka mor'a lijo, ntle le ho hlafuna pele ho nako, e le ho fokotsa phello e halefisang ka mpeng.

Litekanyetso tse latelang tse khothalelitsoeng li bontšoa ka litaelo tsa ts'ebeliso ea matlapa a amitriptyline.

  1. Phekolo ea maemo a sithabetsang. Motsoako oa pele ke 25-50 mg bosiu. Ebe o eketsa butle butle, ka matsatsi a fetang 5 ho isa ho 200 mg ka letsatsi, o arola likala tse tharo. Haeba phello ea kalafo e sa hlahe nakong ea libeke tse peli, tekanyetso ea letsatsi le letsatsi e eketsoa ka boholo bo ka khonehang - 300 mg.
  2. Phekolo ea hlooho ea hlooho, migraines, bohloko bo sa foleng. Phekolo ea kalafo ke 12,5-100 mg ka letsatsi, karolelano ke 25 mg. U ka nka amitriptyline bakeng sa hlooho le mefuta e meng ea bohloko? - hang, bosiu.
  3. Litekanyetso tsa matlapa a Amitriptyline maemong a mang li khethoa ka bonngoe.

Ho nka amitriptyline bosiu ka ho hloka boroko? Haeba ho na le khathatso ea boroko khahlano le semelo sa khatello ea maikutlo, joale sena ha se hloke phetoho meralong e tloaelehileng, moriana o nkuoa joalo ka o hlalositsoe kaholimo.

Bokhachane le pelehi

Moriana ke oa mofuta oa ketso ea C ho lesea ho ea ka kemiso ea FDA (lithutong tsa liphoofolo, ho bile le phello e mpe). Ka hona, ho khethoa ha amitriptyline nakong ea kemolo ho sa rateheng haholo. E sebelisoa feela ha phaello e reriloeng bakeng sa mme e feta kotsi ho lesea.

Ha sethethefatsi se laetsoe nakong ea lactation, joale kalafo eohle e lokela ho emisa ho anyesa.

Sebelisa bongoaneng

Amitriptyline e laeloa hore bana ba phekole bedwetting:

  • matlapa - ho tloha lilemong tse tšeletseng,
  • tharollo - ho tloha ho leshome le metso e 'meli.

Ha e fuoe hangata bongoaneng bakeng sa kalafo ea likomisi tse sithabetsang. Tabeng ena, tekanyetso, khafetsa le nako ea kalafo li khethoa ka bonngoe.

Amitriptyline e nkuoa joang ho bana ba nang le khatello ea maikutlo? - Tekanyetso ka tsela e latelang:

  • a le lilemo li 6 ho isa ho 12 - 10-30 mg ka letsatsi kapa 1-5 mg / kg,
  • bacha ba lilemo li 12 ho isa ho 100 mg.

Ka li-enisis ea bosiu:

  • bana ho tloha ho lilemo tse 6 ho isa ho tse 10 mg ka letsatsi bosiu,
  • bacha ba lilemo li 11-16 - ho fihlela ho 50 mg ka letsatsi.

Sebelisa botsofaling

Botsofaling, e laeloa haholo mafu a sithabetsang a bonolo, bulimia amanosa, maikutlo a kopaneng a maikutlo, psychoses khahlano le schizophrenia le ts'ebeliso ea lino tse tahang.

Mokhoa oa ho isa batho ba tsofetseng? Ka tekanyo ea 25-100 mg bosiu bosiu, hang. Kamora ho fumana phello ea kalafo, fokotsa tekanyetso ho 10-50 mg ka letsatsi.

Litla-morao le mathata

Litla-morao tsa amitriptyline li ntlafala khafetsa 'me li ka phatlalatsoa hoo li fetang phello ea kalafo. Mabapi le sena, qeto ea ho beoa e lula e etsoa ka hloko, 'me bakuli le malapa a bona ba lokela ho lekola maemo a bona nakong ea kalafo.

Litla-morao tse amanang le ts'ebetso ea anticholinergic:

  • pono e fifalitsoeng, bana ba hlapolotsoeng, litho tsa litho tsa bolulo, khatello e eketsehileng ea methapo bathong, ba nang le sekhutlo sa kamore e ka ntle ea leihlo,
  • molomo o omileng
  • pherekano,
  • ho sokela, ho koala sekhahla ka mothapo,
  • ho thatafalloa ho ntša metsi.

Litla-morao tse tsoang tsamaisong ea methapo e bohareng:

  • maemo a ho akheha
  • ho otsela
  • mokhathala o phahameng
  • ho se khonehe
  • ho senyeha hoa mohopolo
  • ferekanya sebakeng,
  • ho tšoenyeha, ho tšoenyeha,
  • hallucinations (hangata ho ba tsofetseng le ba nang le lefu la Parkinson),
  • kelello psychototor,
  • mania, hammoho le hypomania,
  • fokotsa nako,
  • likhathatso tsa boroko
  • bosiu
  • asthenia
  • ho na le hlooho e opang, ho thothomela, ho ts'oaroa ho eketsehileng, dysarthria, paresthesia, myasthenia gravis, ataxia, extrapyramidal syndrome.

Bakeng sa tsamaiso ea pelo le pelo:

  • tachycardia
  • arrhythmia,
  • orthostatic hypotension,
  • Liphetoho tsa ECG ho bakuli ba se nang lefu la pelo,
  • tlola khatello ea mali,
  • tlolo ea infraventricular conduction.

Ho tsoa pampiring ea ka mpeng:

  • pelo e bohloko
  • ho nyekeloa
  • bohloko ba ka mpeng
  • ho hlatsa
  • hepatitis
  • takatso e matla ea lijo
  • botenya kapa ho theola boima ba 'mele,
  • phetoho ea tatso
  • stomatitis
  • lets'ollo
  • ho fifatsa leleme.

Ho tsoa tsamaisong ea endocrine:

  • testicular edema
  • Ho holisa matsoele ho banna,
  • fokotseha kapa keketseho ea libido,
  • mathata a potency
  • eketsa kapa ho fokotseha ha tsoekere ea mali,
  • tlhahiso e fokotsehileng ea vasopressin.

  • ho hlohlona
  • lekhopho la letlalo, urticaria,
  • angioedema (Quincke),
  • photosensitivity

Litla-morao tse ling:

  • tinnitus
  • tahlehelo ea moriri
  • edema
  • feberu
  • ho ruruha ha li-lymph node
  • ho bolokoa ka moroto.

Litaelo tse khethehileng

Nka ka hloko mehato ea ho itšireletsa 'me u lokise kotsi ea ho ba le mathata a teng ka melemo ea kalafo.

  1. Ho pakoa hore baneng, lilemong tsa bocha le bathong ba ka tlase ho lilemo tse 24 ba nang le khatello ea maikutlo le khatello ea kelello, sethethefatsi sena se eketsa ponahalo ea menahano ea boitšoaro le boitšoaro. Ka hona, ho khethoa ha amitriptyline sehlopheng sena sa bakuli ho lokela ho utloahala!
  2. Ho bakuli ba tsofetseng, kalafo e ka baka kholo ea psychosis ea lithethefatsi bosiu. Kamora ho khaotsa lithethefatsi, boemo bo tsitsa ka matsatsi a 'maloa.
  3. Ho bakuli ba nang le khatello ea mali e sa tsitsang, matšoao ana a lokela ho beoa leihlo nako eohle ea kalafo. E kanna ea fokotseha kapa ea eketseha le ho feta.
  4. Ho khothalletsoa ho qoba ho sisinyeha ka tšohanyetso - tsamaea ka hloko ho ea sebakeng se emeng ho tloha bophahamo, kaha ho tsitsipana le ho lahleheloa ke kelello ho ka etsahala.
  5. Tšebeliso ea joala le lithethefatsi tse nang le ethanol li thibetsoe nako eohle ea kalafo!
  6. Haeba kalafo e nang le li-inhibitors tsa MAO e entsoe, amitriptyline e laetsoe pele ho matsatsi a 14 kamora ho hlakoloa ha bona.
  7. Tekano ea bakuli ba fetang 150 mg ka letsatsi e theola monyako oa ts'ebetso ea ho tsitsa mme e eketsa kotsi ea ho ts'oaroa ke batho ba kotsing le bakuli ba nang le lefu la sethoathoa.
  8. Ka khatello ea maikutlo e kholo, kotsi ea ho ipolaea e lula e phahame, ka hona, qalong ea kalafo, ho khothalletsoa tsamaiso e tšoanang ea li-benzodiazepines kapa li-antipsychotic.
  9. Ho bakuli ba nang le mathata a amanang le cyclic, maemo a manic le hypomanic a ka ba teng nakong ea kalafo ka amitriptyline. Maemong ana, fokotsa tekanyetso kapa hlakola sethethefatsi.
  10. Bakeng sa bakuli ba nang le thyrotooticosis, hammoho le ba amohelang lihomone tsa qoqotho, ho ka hlaha litlamorao tsa pelo le pelo.
  11. Hammoho le kalafo ea electroconvulsive, moriana o ka sebelisoa feela tlasa tlhokomelo ea bongaka.
  12. Bakuli ba latelang boroko ba bona ba ka ba le nts'etsopele ea ho holofala ha mala.
  13. Haeba ho na le anesthesia ea lehae kapa e akaretsang, ruri o lokela ho bolella ngaka ea hau ka ho nka amitriptyline.
  14. Mohlomong ho fokotseha ha lacrimation le keketseho ea muus mokhoeng oa meokho. Bakeng sa lilense tsa puisano, sena se ka senya corneal epithelium.
  15. Batho ba nkang amitriptyline nako e telele ba na le kotsi e eketsehileng ea li-caries.
  16. Tlhokomelo e lokela ho nkuoa ha u etsa lintho tse ka bang kotsi tse hlokang tlhokomelo le lebelo la karabelo. Ha u khanna koloi, ho nka amitriptyline ha ho kgothaletswe.

Ho ipapisitse le karabelo e ka bang teng, lihlopha tse latelang tsa batho li lokela ho sebelisa moriana ona ka hloko e kholo:

  • lekhoba la tahi
  • bana le bacha ba ka tlase ho lilemo tse 14,
  • bakuli ba tsofetseng
  • mafu a kang schizophrenia, asthma ea bronchial, lefu la ho ferekana, lefu la mokokotlo, lesapo la mokokotlo oa masapo, pelo le lefu la methapo, khatello ea methapo ea methapo, stroke, ho fokotseha ha ts'ebetso ea motor le mala, sebete, ho hloleha ha bohloko ba mokokotlo, thyrotooticosis, lera la senya la senya. blotder hypotension.

Ho itšetleha ka Amitriptyline

Setlhare sena ha se sa lithethefatsi tse nang le lithethefatsi, hobane ha li na joala bo tahang kapa tse tahang, ha li hlahise temallo ea 'mele ea batho ba bang, joalo ka opiates. Ho itšetleha ka amitriptyline ke kelello feela, e sa amaneng le litakatso tsa 'mele tsa lithethefatsi. Ho utloisisa semelo sa bokhoba ba tahi, o hloka ho tseba molaoana oa ts'ebetso ea lithethefatsi - li-neurotransmitters ha li bola mmeleng ka tekanyo e tloaelehileng, ka hona ha li fetohe nako e telele. Matla a ho nka amitriptyline a fihlelloa ka ho boloka khatello ea nako le nako ea li-serotonin le li-neurotransmitters tse ling li le maemong a phahameng.

Na amitriptyline e lemaletse? Joalo ka li-antidepressants tsohle, e khona ho theha mofuta o itseng oa ho its'epaha - ka ho hlakoloa ka tšohanyetso, matšoao a khutlela hape. Ke ka kutloisiso ena feela moo amitriptyline e ka nkoang e le sethethefatsi, hobane ha sethethefatsi se ntse se nooa, motho o phela hantle, mme ha thupelo e phethetsoe, boemo bo khutlela morao. Hoa etsahala hore bakuli ba tlohele litheko tsa khatello ea litlhare ba fetohe lithethefatsi tsa 'nete. Ka hona, bakeng sa ho khetholla kotsi e ka 'nang ea hlaha ho amitriptyline, kamohelo ea eona e hlakotsoe butle butle, pele khoeli e fela.

Ho tlohela maikutlo

Ka ho lahla lithethefatsi ka matla, haholo-holo haeba li entsoe ka tekanyetso e phahameng, ho ka etsahala hore nts'etsopele ea amitriptyline ea ho ntša maikutlo. Matšoao ke afe?

  • ho nyekeloa
  • ho hlatsa
  • hlooho e bohloko
  • lets'ollo
  • likhathatso tsa boroko
  • malaise
  • bosiu.

Leha e le ho hloleha butle-butle, ho tšoenyeha ka koloi, ho teneha, likhathatso tsa boroko, ho ba le litoro tse matla.

Ho tlosa amitriptyline ho nka nako e kae? - boemo bo bonoa ha nako e ntse e tsamaea, ho fihlela lithethefatsi tsohle li tlosoa, ke hore matsatsi a 8-14. Liponahatso tse ling li se li ntse li tsoela pele ka kelello ea tlhaho.

Morero oa ho fokotsa amitriptyline ke ho fokotseha butle butle ka tekanyetso ea kalafo nakong ea khoeli, ho qala ka ¼ ho fihlela e hlakotsoe ka botlalo.

Lisosa tsa bosholu ba joala

Ho eketsa tekanyetso ea tekanyetso e le 'ngoe ea lithethefatsi hangata ho hlaha maemong a latelang:

  • ho se latele tekanyetso e fanoeng ke ngaka (ka boomo kapa ka phoso),
  • Tšebeliso e sa lefelloeng ea moriana ntle le taelo ea ngaka,
  • motsoako oa sethethefatsi ka tekanyetso ea kalafo le lino tse tahang.

Matšoao a overdose

Ho latela boholo ba amitriptyline e nkuoeng, li-degrees tsa 3 tsa overdose lia khetholoha - li bonolo, li leka-lekana ebile li matla, tseo ntle le mehato ea ho tsosa li qetellang li bolaile maemong a 100%.

Bana ba tsotella haholo ho feta tekano kapa ho bolaea.

Tekanyetso e fokolang ea amitriptyline e hlahisoa ke matšoao a latelang:

  • molomo o omileng
  • ho sokela
  • ho hloka urination
  • dyspepsia.

Lipontšo tsa tšebeliso e feteletseng ea tekanyo e leka-lekaneng le e boima li lula li tebile mme li hloka tlhokomelo ea bongaka hanghang.

  1. Ho tsoa ho tsamaiso ea methapo e kholo - ho otsela ho eketsehileng, ho se tsitse, ho tšoenyeha ho sa hlokahaleng, ho ts'oaroa ha sethoathoa, ho hlasimoloha, ho bua hampe, ho satalla ha mesifa, pherekano, tahlehelo ea sebaka, ho fokotseha ha maikutlo, ho ferekana kelellong, ho ferekana, ho akheha.
  2. Ho tloha lehlakoreng la pelo le methapo ea mali - arrhythmia, tachycardia, tlolo ea tsamaiso ea intracardiac, ho nyekeloa ke pelo, ho fokotseha ho hoholo ha khatello ea mali, ho ts'oha, ho tšoaroa ha pelo (ka seoelo).
  3. Lipontšo tse ling ke ho fokotseha hoa moroto oa hau, ho fihlela ho ba sieo ha lona ka botlalo, hyperthermia, ho fufuleloa ho eketsehileng, ho hlatsa, ho phefumoloha, khatello ea maikutlo a ho hema, cyanosis, ho hlohlona ha meno le sebete.
  4. Boemong ba ho bola, khatello ea mali e oa, lipopae ha li arabe, li felloa ke matla, ho hlohlona, ​​ho nyekeloa ke pelo, le ho ts'oaroa ha phefumoloho ho hlaha.

Motsoako o bolaeang ke ligrama tse 1,5 tsa amitriptyline tse nkuoeng ka nako. Leha ho le joalo, tse fokolang li lekane bakeng sa bana.

Phekolo ea chefo

Matšoao a pele a ho sebelisa tekanyetso e kholo ea bongoana, ho hlokahala ho etsa mehato e latelang ea pele ho kalafo.

  1. Letsetsa ambulense.
  2. Fa mokuli hore a noe litha e le nngwe tsa metsi le ho hlatsa. Pheta mokhoa ona ho fihlela ho hlaha metsi a hlatsoang a hloekileng.
  3. Nka li-enterosorbents ho fokotsa ho kenngoa ha moriana maling - Enterosgel, khabone e tsitsitseng, Atoxil, MP ea Polysorb le ba bang.
  4. Haeba motho a hlokofetse, ho hlokahala hore a mo retelehele ka lehlakoreng le leng.

Phekolo ea chefo ea amitriptyline e etsoa ka tlhokomelo e matla mme e kenyelletsa mehato e latelang ea kalafo.

  1. Ts'oaetso ea maemo a tšohanyetso.
  2. Ho hlahisoa ha tharollo ea letsoai ho boloka khatello ea mali, acidosis e nepahetseng, tekanyo ea motlakase-oa motlakase.
  3. Ho nka li-inhibitors tsa cholinesterase ho felisa lipontšo tsa anticholinergic.
  4. Ho kenngoa ha glucocorticoids ka ho theoha ho matla ha khatello ea mali.
  5. Ho fana ka litlhare tsa antiarrhythmic bakeng sa pelo.
  6. Tlhahlobo ea mokuli ea lihora tse 24 ka ho shebella khatello ea mali le sekhahla sa pelo.
  7. Maemong a matla - ts'usumetso, mehato ea anticonvulsant, tšelo ea mali.

Hemodialysis le diuresis tse qobelloang ha lia bontšoa hore li sebetsa hantle ho overdosing le amitriptyline.

Ha ho na pheko e tobileng ea chefo ea amitriptyline.

Liphello tsa chefo

Ho sebelisa moriti o mongata haholo hoa bolaea, le haeba tlhokomelo ea bongaka e ile ea fanoa ka nako. Sesosa sa lefu ke ho ts'oaroa ha pelo, ho phefumoloha, ho hoama haholo.

Liphetho tsa overdose ea amitriptyline e lula e le teng, le haeba motho a ile a khona ho phela:

  • liphetoho tsa kelello, khatello ea maikutlo e matla,
  • sa foleng renal le hepatic ho hloleha,
  • pherekano ea morethetho oa pelo.

Litlamorao tse salang li bonoa bophelong bohle 'me li hloka kalafo ea lithethefatsi kamehla.

Analogue ea sebopeho sa amitriptyline ke lithethefatsi tse tsoang ka ntle ho naha, e leng Saroten Retard, e entsoeng ke H. LUNDBECK A / S (Denmark).

Ke eng hape e ka nkang sebaka sa amitriptyline? Li-analogues tsa sehlopha ke Anafranil, Doxepin, Melipramin, Novo-Tryptin - lithethefatsi li na le matla a tšoanang, empa li fapana ka sebopeho. Lithethefatsi tsena ke li-analog tsa mehleng ea kajeno tsa amitriptyline ntle le ho ba le litlamorao e le tšobotsi ea ho nka khatello ea maikutlo.

Ho sebelisana le lithethefatsi tse ling

Pele u qala kalafo ka amitriptyline, o hloka ho bolella ngaka ea hau ka meriana eohle e nooang e sa khaotse.

  1. E ka se kopantsoe le li-inhibitors tsa MAO.
  2. Amitriptyline e ntlafatsa phello ea inhibitory bokong ba methapo ea kutlo, hypnotics, analgesics, lithethefatsi bakeng sa ho phekola lefu lena, li-antipsychotic le lithethefatsi tse nang le ethanol.
  3. E fokotsa ts'ebetso ea li-anticonvulsants.
  4. E ka hlalosoa hammoho le lipilisi tsa ho robala (mohlala, "Sonapax" e nkuoa le amitriptyline). Empa kopanong ena, e eketsa ts'ebetso ea anticholinergic ea Sonapax - ka mantsoe a mang, e fokotsa bokhoni ba lisele tsa boko ho fetisetsa lipontšo tsa methapo.
  5. Hammoho le litlhatlhobo tse ling, litlamorao tsa lithethefatsi ka bobeli lia ntlafatsoa.
  6. Ha li kopantsoe le li-antipsychotic le lithethefatsi tsa anticholinergic, mocheso oa 'mele o ka nyoloha' me ho hlaha metsoako ea litho tsa ka mpeng e ka holang.
  7. Amitriptyline e ntlafatsa litlamorao tse matla tsa catecholamines le adrenostimulants, e eketsa kotsi ea tachycardia, cardhac arrhythmias, le khatello e matla ea methapo ea mali.
  8. E ka fokotsa phello ea antihypertensive ea guanethidine le lithethefatsi tse tšoanang.
  9. Ha e kopantsoe le lintlha tse tlotsitsoeng ka coumarin kapa indandion, mosebetsi oa anticoagulant oa ho qetela o ka eketseha.
  10. Hammoho le cimetidine, khatello ea amitriptyline maling a mali e eketseha, e leng ho eketsang monyetla oa litlamorao.
  11. Inducters ea microsomal sebete enzymes (carbamazepine le li-barbiturates tse ling) e fokotsa khatello ea amitriptyline.
  12. Quinidine e fokotsa metabolism ea amitriptyline.
  13. Lihormone tse nang le estrogen li eketsa bioavailability ea amitriptyline.
  14. Hammoho le disulfiram le acetaldehyde dehydrogenase inhibitors, delirium e ka nts'etsapele.
  15. Amitriptyline e khona ho ntlafatsa khatello ea maikutlo, e hlahileng ka morao ho li-glucocorticoids.
  16. Hammoho le lithethefatsi bakeng sa kalafo ea thyrotooticosis, menyetla ea ho ba le agranulocytosis ea eketseha.
  17. Ho kopana ha li-nootropics ho lebisa ho fokotseng ketso ea lithethefatsi tsena le ho eketsa menyetla ea litla-morao.
  18. Tlhokomeliso e lokela ho kopantsoe le digitalis le baclofen.
  19. Ho tsamaisana hantle ha amitriptyline le lithibela-mafu, li-antiviral lithethefatsi (jk., Acyclovir). E ka kopantsoe joalo ka ha u laetsoe ke ngaka.

Lipotso tse botsoang khafetsa

Re tla araba lipotso tse tsebahalang tse bokelitsoeng motheong oa lipotso tse batloang tse amanang le likarolo tsa ts'ebeliso ea amitriptyline le ho kopanngoa ha lona le lithethefatsi tse ling tse sa boletsoeng ho litaelo tsa semmuso.

  1. Na lengolo la "amitriptyline" kapa "ha le fuoe"? Lipehelo tsa thekiso ea litlhare - ka taelo feela.
  2. Amitriptyline le donormil li ka amahanngoa le eng, na meriana ee e ka kopanngoa? Motsoako ona o etsoa ke lingaka - amitriptyline e tla ntlafatsa phello ea Donormil. Empa lithethefatsi li nooa ka linako tse fapaneng tsa letsatsi 'me li kenngoa ka thata sepetlele tlasa tlhokomelo ea ngaka.
  3. Amitriptyline le phenibut li amana joang? Kaha "Phenibut" e bua ka nootropics, hammoho le amitriptyline, litlamorao tsa kalafo ea lithethefatsi ka bobeli li fokotsehile, mme menyetla ea litlamorao e ea eketseha. Motsoako ona o lokela ho tšohloa le ngaka ea hau.
  4. Na amitriptyline e lumellana le corvalol? Lithethefatsi tsena ha li hanane, empa Corvalol e na le phenobarbital, e ka ntlafatsang phello ea amitriptyline.
  5. Na carbamazepine (Zeptol, Carbalepsin Retard, Tegretol, Finlepsin) e tsamaisana le amitriptyline? Lithethefatsi li ka tsamaisoa hammoho, empa ho lokela ho hopoloa hore, mohlomong, keketseho ea phello ea inhibitory tsamaisong ea methapo ea methapo, ho fokotseha ha matla a anticonvulsant ea carbamazepine le ho fokotseha hoa khatello ea amitriptyline maling.
  6. Na amitriptyline e ka nkuoa ka phenazepam? Lithethefatsi tse joalo li ka laeloa ka ho tšoana feela lithutong tse khutšoane, ho potlakisa phomolo ea matšoao le ho fokotsa litlamorao tsa antidepressant.
  7. Na amitriptyline le cinnarizine lia lumellana? Ho laela ho a khonahala, empa tlasa taolo ea ngaka, hobane ka kopanyo ena phello ea khatello ea maikutlo e tla matlafatsoa.
  8. Fluoxetine le amitriptyline li ka kopantsoe ka eng? Fluoxetine le eona e kokobetsa khatello ea maikutlo, empa e tsoa sehlopheng se fapaneng ebile e na le ts'ebetso e ntle ea ts'ebetso. Motsoako ona o ka etsahala ka ho sebelisa litekanyetso tse fokolang tsa kalafo tsa meriana le feela joalo ka ha u laetsoe ke ngaka, empa ho kotsi bakeng sa nts'etsopele ea litla-morao.
  9. Na Velafax e tsamaellana le amitriptyline? Hape ke antidepressant, ts'ebetso ea ts'ebetso ea eona e fapaneng. Ho kopana ha tsona hoa khoneha, empa litlhare li arotsoe ka nako - "Velafax" hoseng, le amitriptyline mantsiboea ka tekanyetso e tlase mme ba lokela ho lekola karabelo ea 'mele bakeng sa ho kenyelletsa phello ea thibelo ea methapo ea methapo e kholo.
  10. Na amitriptyline e tsamaellana le piracetam? Li-nootropics ha li khothalletsoe ho kopantsoe le li-antidepressants ka lebaka la phapang ea ketso ea tsona - e hlohlelletsang khahlanong le ho thoba. Ho sebetsa hantle ha litlhare tsena tse peli ho ka fokotseha 'me kotsi ea litla-morao e ka eketseha. Haeba motsoako o joalo o laetsoe ke ngaka, joale ho bohlokoa hore o arole ho kenella ha matlapa ka nako.
  11. Nka noa amitriptyline le Paxil ka nako e le 'ngoe? Tsena ke li-antidepressant tse peli tse tsoang lihlopheng tse fapaneng. Motsoako o joalo oa sebelisoa, empa o ke ke oa inkela o le mong, hobane ho na le kotsi ea ho ntlafatsa litlamorao tsa tsona ka bobeli.
  12. Amitriptyline le Eglonil li amana joang? Hona ke antipsychotic e nang le litlamorao tsa antipsychotic, kahoo ha e sebelisoa hammoho, ho na le monyetla oa ho eketsa phello ea thibelo ho ts'ebetso ea methapo e bohareng. Haeba motsoako o joalo o etsoa, ​​joale lithethefatsi li fanoe ka linako tse fapaneng.
  13. Nka fuoa escitalopram ka amitriptyline? Ho kopana ha li-antidepressant habeli ha ho tšoane kamehla. Ka nako e 'ngoe motsoako ona o etsoa ka khatello e matla ea maikutlo, empa phekolo e ntle ka ho fetisisa e hlaha ka ho kopanya antidepressant le tranquilizer.
  14. Nka nka Afobazole le amitriptyline hammoho? Lithethefatsi tsena lia lumellana kaha Afobazol e bua ka li-tranquilizer 'me hangata e fanoa hammoho le li-antidepressants. Empa khahlanong le semelo sa amitriptyline e matla, litlamorao tsa Afobazole li ka lahleha, ka hona, ke ngaka feela e lokelang ho khetha litekanyetso tsa kalafo.
  15. Na amitriptyline le Atarax li ka nkoa hammoho? Sena ke lithethefatsi se tsoa ho sehlopha sa batho ba khutsitseng, ka hona, ho ka etsahala hore se kopantsoe le amitriptyline liprofinse tse sithabetsang. Empa kamohelo ea bona ka linako tse fapaneng ea hlokahala.
  16. Na ho na le lithethefatsi tse ka rekoang ka holim'a k'homphieutha ka amitriptyline? Ho na le litlhare tse bobebe tse sa tlameng, litlamorao tsa tsona tse ka hlahisoang ke lithethefatsi tse felisang khatello ea maikutlo - Persen, Novo-Passit, Deprim, Azafen le ba bang. Empa ho rekisa lithethefatsi ntle le lengolo la ngaka ha ho bolele hore u ka fana ka kalafo ka boeona!
  17. Na amitriptyline le Finlepsin li ka nkuoa hammoho? Motsoako ona o sebelisetsoa ho phekola lefu la sethoathoa, hammoho le neuralgia le bohloko, kahoo ho na le monyetla oa ho eketsa phello ea thibelo ea methapo ea methapo ea methapo ea methapo kapa ho fokotsa khatello ea mali maling.
  18. Na amitriptyline e ka nkoa e le lipilisi tsa ho robala? Ha boroko bo sa tsamaisane le khatello ea maikutlo, sethethefatsi ha se bontšoe.
  19. Haeba amitriptyline hangata e nkuoa, litlamorao ke life? Phekolo ea nako e telele e tsoelang pele e lula e amahanngoa le kotsi e kholo ea litla-morao. Kalafo e nang le moriana o tebileng joalo e lokela ho etsoa feela ka tlasa tlhokomelo ea ngaka le tekanyetso e lekaneng.
  20. Na amitriptyline e ka fuoa motho ea tahiloeng? Che, ha e lumellane ka botlalo le joala!
  21. Na amitriptyline e na le litlamorao kapa che? E, phello ea kalafo ea moriana ona e ea eketseha ebile e hlaha ka botlalo ka mor'a libeke tse 2-3.
  22. Hobaneng ha ba nona mafura ho tsoa ho amitriptyline? E 'ngoe ea litlamorao tsa eona ke takatso e matla ea lijo. Ka linako tse ling sena se lebisa ho boima ba 'mele.
  23. Na amitriptyline e eketsa kapa e fokotse khatello ea mali? Setlhare se khona ho se fokotsa le ho se eketsa. Lirama tsa matšoao li ka bonoa letsatsi lohle.
  24. Ho tlosa bofokoli joang ka mor'a ho nka amitriptyline? Tlatsetso ea lithethefatsi e lula matsatsi a 7-14. Haeba maemo a sa ntlafale, o lokela ho lekola lethal dose kapa o nkele e 'ngoe ka lona.
  25. Amitriptyline e sebetsa ka nako e kae? Sesebelisoa se sebetsang se kena maling nakong ea metsotso e 30 ka mor'a ho kenella 'me se lula moo ka lihora tse ka bang 7-10 (lihora tse 28 tse phahameng). Hoo e ka bang tekanyo e le 'ngoe ea moriana o amoheloang.
  26. Ke eng e tsoang ka mor'a nako efe kapa efe e tsoang ho 'mele? Ho felisoa ha eona ka botlalo ho etsahala matsatsi a 7-14 kamora hore pheletso e amoheloe.
  27. Ke ngaka efe e hlalosang amitriptyline? - ngaka ea mafu a kelello.
  28. Nka nka amitriptyline nako e kae ntle le khefu? Nako ea kalafo e nka likhoeli tse robeli.

Amitriptyline - lithethefatsi tse matla tse amanang le li-antidepressants tsa moloko oa "khale". Litlamorao tsa eona tse matla ka linako tse ling li feta melemo ea kalafo. Ka hona, qeto ea ho e nka e lokela ho etsoa feela ke ngaka. Ho ipusa ka setlhare se joalo ho sokela bophelo!

Sebopeho le thepa

Moriana ona o amoheloa ho tsa bongaka joalo ka antidepressant e sebetsang. Ke ea mofuta oa mofuta oa tricyclic, hape e na le liketso tse latelang:

  • e le moemeli oa li-analgesic oa mantlha,
  • e le mokhoa oa ho fokotsa takatso ea lijo le ho felisoa ha maemo a ho hloka moroto, moemeli ea nang le litšobotsi tsa antiserotonin,
  • e khothalletsoa hore e sebelisoe ho bulimia mothosa.

E fumaneha ka mokhoa oa litafole kapa tharollo. Hangata, ho sebelisoa mofuta oa letlapa kalafo. Mmala o ka ba mosoeu kapa o mosehla. Fomu ea tokollo - sephara-silinda.

Ho na le chamfer matlapeng, e netefatsang litekanyetso tse nepahetseng joalo ka ha u laetsoe ke ngaka ha u beha tlhahiso ea amitriptyline. Litaelo tse qaqileng tsa tšebeliso ea amitriptyline matlapeng a tlameha ho kenngoa ka lebokoseng la karete.

Sena sea khahla! Hobaneng ha diazepam e laetsoe: litaelo tsa tšebeliso (antide)

Ha u fana ka taelo, ngaka e tla u bolella ka botlalo mabapi le amitriptyline: se thusang, hore na o se nka joang ka nepo.

Karolo e khethollang ke ketso e sebetsang ea bohloeki le bohareng ba anticholinergic, sedation se matla.

Ha ho nka, ho na le keketseho ea khatello ea serotonin le norepinephrine tsamaisong ea methapo e bohareng, hammoho le ts'ebetso ea ho fokotsa boemo ba bona ba ho khutlisa mokokotlo.

Ha e sebelisoa

Lebaka le ka sehloohong la ho khethoa ho nkuoa ho nkoa e le khatello ea maikutlo, e tsamaeang le:

  • khathatso ea boroko
  • ho hloka boroko
  • ho tšoenyeha ho eketsehileng,
  • ho ferekana
  • lipontšo tse ling tsa linaha tse sithabetsang, ho kenyelletsa le ho bakuli ba bongoaneng.

E laeloa mafu a latelang:

  • maemong a ho khetholla lefu la pelo.
  • ka ho khetholla matšoao a ho tsubang,
  • ha ho na le enursis ea bosiu, empa ha ho na hypotension ea bladder,
  • maemong a bohloko ba ho kula bo sa foleng, ho kenyeletsoa le bo bakiloeng ke lefu la mofets'e,
  • ha bohloko ba sefahleho bo bonahala.
  • ka lefu la morao-rao le amanang le koluoa ​​le maemo a mang.

Ho ka fanoa ka antidepressant amitriptyline ka hlooho e bohloko hape e khothalelitsoe ho bakuli ba nang le liso tsa ka mpeng.

Elitlamorao tsa ho loants'a linaha tse tepelletsang li bonahala kamora ho etsa kopo bonyane libeke tse tharo.

Order Order

Indasteri ea meriana e fana ka mefuta e 'meli ea tokollo: tharollo le matlapa. Maemong a mangata, pilisi e fanoa ka mor'a lijo.

Sena sea khahla! Seo u se khethang le ho tsoa ho eng ho nka Asafen: lipontšo tsa ts'ebeliso

Li ka khopisa mabota a mpa, ka lebaka lena ha ho kgothaletswe ho li hlafuna. Ha e nooa ka metsi.

Mehatong ea pele ea kalafo ho sebelisoa moriana oa 25-50 mg. Tekanyo e khothalletsoa ho nooa bosiu. Joalokaha e amoheloa nakong ea matsatsi a mahlano litheko tsa litekanyetso li etsahala ho fihlela ho 200 mg ka letsatsi.

Chelete ena e ajoa ka litekanyetso tse tharo kamora lijo tsa hoseng, lijo tsa mots'eare le lijo tsa mantsiboea. Haeba ho se na phello e ntle kamora libeke tse peli tsa tsamaiso, tekanyetso e ka eketsoa ho 300 mg.

Ha u khetha tharollo, e tsamaisoa ka mokhoa o ts'oaroang ka 20-25 mg ka ente e ngoe. Liente li etsoa makhetlo a 4 ka letsatsi, butle-butle li fetisetsa mokuli tšebeliso ea lithethefatsi ka mokhoa oa matlapa.

Haeba moriana o sebelisoa kalafo ea bohloko, migraine, litekanyetso li fihla ho 100 mg ka letsatsi.

Mefuta ea mefuta e fapaneng ea karabelo

Pheko ena e na le litlamorao tse ngata.

Bakeng sa amitriptyline, foromo ea tokollo ka mokhoa oa matlapa kapa tharollo e hlile e tsamaisana le litaelo tse qaqileng tseo ho tsona liphetoho tse joalo li ka hlahisoang ka botlalo.

Ho kenyelletsa ha o nka ho ka bonoa:

  • Lipontšo tse mpe tsa tsamaiso ea methapo, tse kenyeletsang eketseha haholo, ponahalo ea maemo a nyahamisang le lipono tse makatsang, ponahalo ea matšoenyeho a koloi, lipontšo tse eketsehang tsa matšoao a nyahamisang le a mang.
  • Karolong ea methapo ea pelo le litla-morao, litla-morao li tšoauoa ka ho ferekana, ponahalo ea tšitiso ea methapo ea pelo, tachycardia, le keketseho ea meketjana ea ho otla ha pelo.
  • Ho ts'oaroa hoa lijo ho lemohuoa, ho kenyelletsa ho fifatsa leleme, hepatitis, ponahalo ea liphetoho tatsolinyeoe tsa ho hlatsa le lets'ollo.
  • Litlamorao tsa Anticholinergic li ka hlaha ka mokhoa oa pono e fifalitsoeng ea pono, keketseho e kholo ea khatello ea intraocular, tachycardia, delirium. Pherekano ea letsoalo e bonoa mme boemo ba mofufutso bo fokotsehile.

Lipontšo tse mpe li lemohuoa kamora ho phethoa ha thupelo kapa ho hlakoloa.Ho kenyelletsa le litoro tse sa tloaelehang, ho opeloa ke lets'ollo le ho nyekeloa pelo, ho hlobaela le hlooho e sa khaotseng ho ka qala.

Haeba ho e-ba le karabelo e mpe, o lokela ho etela ngaka hang-hang ho fetola kalafo, hobane bakeng sa moriana o kang amitriptyline, litla-morao tse ka bang kotsi ho boemo ba bophelo ba mokuli.

Sena sea khahla! Hobaneng adaptol e thusa: litaelo tsa ho sebelisoa

Le ha matšoao a khothalelitsoeng bakeng sa ts'ebeliso ea amitriptyline a le bohlokoa, hoa hlokahala tlhaiso e tsoelang pele ea bophelo bo botle ba mokuli. Lintlha tse kang li-contraindication le karabelo e fapaneng e fapaneng li lokela ho tsotelloa nakong ea nts'etsopele ea nako ea kalafo le khetho ea meriana.

Haeba liphoso li entsoe nakong ea ho kenella 'me ho ba le overdose ho etsahetse, e tla iponahatsa e le lipontšo tse mpe karolong ea litsamaiso tsohle tsa' mele. Ho kenyelletsa tsamaiso ea methapo e bohareng, pelo le methapo ea methapo. Ka mofuta oa ponahatso, li tšoana le litlamorao tsa ho amoheloa.

Ho sebelisa bosholu ba joala ha u sebelisa moriana matlapeng le tharollong. Haeba tekanyetso ea ntho e fetisoa ha ho sebelisoa tsamaiso ea molomo, ho etsoa sefuba sa tšohanyetso. Ho bohlokoa ho letsetsa ambulense hanghang. Pele ngaka e fihla, ho hlatsuoa ho etsoa ka bo bona ke mokuli le litho tsa lelapa la hae. Karabelo e joalo ea ts'ebetso e hlokahala ka lebaka la lenane le kotsi la lipontšo tse mpe, tseo maemong a mang li ka qetellang ka ho ts'oaroa ha pelo.

Menahano ea lithethefatsi

Sesebelisoa sena se na le li-analogues tse ngata. Ka kakaretso, likhetho tse fetang mashome a mane tsa lithethefatsi li ka fanoa.

Ho kenyelletsa lithethefatsi: gelarium hypericum, lotonica, dystonicum, azafen, neurol, valdoxane, citron, gerfonal.

Khetho ea analogue ea lithethefatsi e etsoa ke setsebi. Boithati ho hlakola kapa ho busetsa sebaka ha hoa khothalletsoa.

Lithethefatsi tsena tse tšoanang li thusa ho imolla khatello e matla ea maikutlo le khatello ea maikutlo. Bakeng sa amitriptyline, li-analogu li ngata ebile li u lumella ho khetha khetho e sebetsang ea kalafo. Lithethefatsi tse tšoanang le ketso e sebelisitsoeng bakeng sa amitriptyline li fana ka thuso ho bakuli bohle ba etsang kopo.

Melao e Khethehileng ea Tšebeliso

  • Haeba ts'ebeliso ea tharollo e laetsoe, kenyelletso e etsoa feela sepetlele le tlhaiso e khafetsa ea lingaka. Matsatsing a pele a ho amoheloa ka mofuta ofe kapa ofe, mokuli o lokela ho boloka phomolo ea hae ka thata.
  • Pele o nka, maemo a khatello ea mali a hlahlojoa.
  • Ho tsoa ho ethanol nako eohle ea tsamaiso e tlameha ho tloheloa ka ho felletseng, motsoako o joalo o kotsi bophelong ba mokuli.
  • Qetellong ea tšebeliso ea lithethefatsi kalafo e hlokahala butle butle, ka mokhoa o hlophisitsoeng o fokotsa litekanyetso tsa letsatsi le letsatsi. Ka ho khaotsa ho sebelisoa ha karolo e kholo ea bakuli, ho bonoa "syndrome ea ho ntša" e ka lebisang tlhaselong e ncha le e nyahamisang.
  • Ha o nka, taolo ea bokgoni ba nts'etsopele ea manic States, eo hangata e ka bonoang ka mathata a cyclic le a amanang le khatello ea maikutlo, e hlokahala.

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