Matlapa a Glurenorm - litaelo tsa semmuso bakeng sa tšebeliso

Sebopeho
Letlapa le le leng le na le:
Lintho tse sebetsang: glycidone - 30 mg,
Baeti: lactose monohydrate, starch e omisitsoeng ea poone, starch ea poone e qhibilihang, magnesium stearate.

Tlhaloso
E boreleli, e chitja, e tšoeu ka mekhabiso e betliloeng ea letlapa, e nang le notch ka lehlakoreng le leng 'me e ngotsoe "57C" ka mahlakoreng ka bobeli, likotsi, logo ea k'hamphani e ngotsoe ka lehlakoreng le leng.

Sehlopha sa Pharmacotherapeutic:

Khoutu ea ATX: A10VB08

Melemo ea pharmacological
Glurenorm e na le litlamorao tsa pancreatic le extrapancreatic. E matlafatsa secretion ea insulin ka ho theola monyako oa pancreatic beta-cell glucose, e eketsa kutloisiso ea insulin le ho tlamahanya le eona liseleng tsa sepheo, e ntlafatsa sephetho sa insulin ho mesifa le mokokotlong oa "glucose" (e eketsang palo ea li-insulin receptor ho li-tishu tse kahare), hape e thibela lipolysis ka lithane tsa adipose. Ketso ea mokhatlong oa bobeli oa insulin secretion, e fokotsa litaba tsa "glucagon" maling. E na le phello ea hypolipidemic, e fokotsa mali a mali a "thrombogenic". Matla a hypoglycemic a hlaha kamora lihora tse 1,0-1,5, phello e phahameng - kamora lihora tse 2-3 mme e nka lihora tse 12.

Mofumahali
Glycvidone e potlakisa ebile e batla e ananeloa ka botlalo ho tsoa ho tšilo ea lijo. Kamora ho kenella ka tekanyetso e le 'ngoe ea Glyurenorm (30 mg), khatello e phahameng ea lithethefatsi ho plasma e fihlella ka mor'a lihora tse 2-3, ke 500-700 ng / ml mme kamora lihora tse 14-1 e fokotsehile ka 50%. E na le metabolism ka botlalo Karolo e ka sehloohong ea metabolites e epolloa kahara le ka mala. Ke karolo e nyane feela ea metabolites e epolloang ka har'a moroto. Ho sa tsotelehe tekanyetso le mokhoa oa tsamaiso, hoo e ka bang 5% (ka sebopeho sa metabolites) ea palo e laoloang ea lithethefatsi e fumanoa ka har'a moroto. Boemo ba tsoekere ea glurenorm ke liphio bo lula bo fokola esita le ka tšebeliso e tloaelehileng.

Matšoao
Type 2 lefu la tsoekere ho bakuli ba lilemo li mahareng le ba tsofetseng (ka ho se sebetse hantle ha kalafo ea ho ja).

hypersensitivity ho sulfonylureas kapa sulfonamides,

mofuta oa 1 lefu la tsoekere

lefu la tsoekere ketoacidosis, thoroma, koma,

boemo kamora ho pancreatic resection,

acute hepatic porphyria,

ho hloka matla ha sebete,

maemo a mang a hlobaetsang (mohlala, mafu a tšoaetsanoang kapa ho buuoa ho hoholo ha ho bontšoa kalafo ea insulin),

boimana, nako ea ho anyesa.

Ka tlhokomelo
Glurenorm e lokela ho sebelisoa bakeng sa:

febrile syndrome

maloetse a qoqotho (a nang le ts'oaetso),

bokhoba ba joala.

Boimana le nako ea ho anyesa
Ts'ebeliso ea Glyurenorm nakong ea kemolo e tšoaetsanoa.
Haeba ho ima, o lokela ho khaotsa ho sebelisa lithethefatsi le ho etela ngaka hang-hang.
Haeba ho hlokahala ho sebelisa moriana nakong ea matsoele, ho anyesa ho lokela ho emisoa.

Tekanyetso le tsamaiso
Setlhare se fanoa ka molomo.
Khetho ea lethal dose le regimen li lokela ho etsoa tlasa taolo ea metabolism ea carbohydrate. Tekanyetso ea pele ea Glyurenorm hangata ke matlapa a 14 (15 mg) ka nako ea lijo tsa hoseng. Haeba ho hlokahala, eketsa tekanyetso butle butle, ho latela likhothaletso tsa ngaka. Ho eketsa tekanyo ea lipilisi tse fetang 4 (120 mg) ka letsatsi hangata ha ho lebise ho eketseheng ho eketsehileng ha phello. Haeba tekanyetso ea letsatsi le letsatsi ea Glyurenorm e sa fete matlapa a mabeli (60 mg), e ka fuoa tekanyetso e le 'ngoe, nakong ea lijo tsa hoseng. Ha u fana ka tekanyetso e phahameng, phello e ntle ka ho fetisisa e ka fumaneha ka ho nka tekanyetso ea letsatsi le letsatsi e arotsoe ho litekanyetso tse peli. Tabeng ena, tekanyo e phahameng ka ho fetisisa e lokela ho nooa lijong tsa hoseng. Glurenorm e lokela ho nooa le lijo, qalong ea lijo.
Ha u nka moemeli oa hypoglycemic ea molomo ka ts'ebetso e ts'oanang ea ts'ebetso tekanyetso ea pele e khethoa ho latela tlhahlobo ea lefu ka nako ea tsamaiso ea moriana. Motsoako oa mantlha hangata ke 1/1 ho isa ho pilisi e le 'ngoe (15-30 mg).
Haeba monotherapy e sa fane ka phello e lebelletsoeng, ho khethoa ha Biguanide ho ka etsahala.

Ho tsoa pampiring ea ka mpeng:
Ho feta 1%	ho nyekeloa ke pelo, ho hlatsa, ho sokela, lets'ollo, ho felloa ke takatso ea lijo, cholera ea intrahepatic (1 nyeoe).
Tsa letlalo:
0,1-1%	ho hlohlona, eczema, urticaria (1 kesi), lefu la Stevens Johnson.
Ho tsoa tsamaisong ea methapo:
0,1-1%	- hlooho e opang, ho tsekela, ho ferekana.
Ho tsoa ho hematopoietic system:
Ka tlase ho 0,1%	thrombocytopenia, leukopenia (1 kesi), agranulocytosis (1 kesi).

Bongata
Maemo a Hypoglycemic a khonahala.
Sebakeng sa nts'etsopele ea boemo ba hypoglycemic, tsamaiso ea hang-hang ea tsoekere ka hare kapa kahare e ea hlokahala.

Ho sebelisana le lithethefatsi tse ling
Salicylates, sulfonamides, lithibelo tsa phenylbutazone, lithethefatsi tse khahlanong le lefuba, chloramphenicol, tetracyclines le li-coumarin derivatives, li-cyclophosphamides, li-inhibitors tsa MAO, li-antibi tsa ACE, clofibrate, block-adrenergic blocker, drugtholytics (hypathictics) le antipsolidi acid.
Ho a khonahala ho fokotsa phello ea hypoglycemic ha u ntse u hlahisa Glurenorm le sympathomimetics, glucocorticosteroids, lihormone tsa qoqotho, tsoekere, thiazide diuretics, lithibela-pelehi tsa molomo, diazoxide, phenothiazine le lithethefatsi tse nang le nicotinic acid, barbiturates, rifampinin, fen. Ntlafatso kapa tumeliso ea phello e hlalositsoe le H₂-Blockers (cimetidine, ranitidine) le joala.

Litaelo tse khethehileng
Hoa hlokahala ho latela ka tieo litlhahiso tsa ngaka tse reretsoeng ho tloaetsa metabolism ea carbohydrate ho mokuli. Se ke oa emisa kalafo u le mong ntle le ho tsebisa ngaka ea hau. Le ha glurenorm e pepesoa hanyane ka har'a moroto (5%) mme hangata e mamelleha hantle ho bakuli ba nang le lefu la liphio, kalafo ea bakuli ba nang le bothata bo matla ba ho phekola ba leqhubu e lokela ho etsoa ka tlasa tlhokomelo ea bongaka e haufi.
Bakuli ba nang le lefu la tsoekere ba na le tšekamelo ea ho hola mafu a amanang le lefu la pelo, kotsi ea eona e ka fokotsoang feela ka ho khomarela lijo tse boletsoeng. Litho tsa molomo tsa hypoglycemic ha lia lokela ho nka sebaka sa phepo eu lumellang ho laola boima ba 'mele ba mokuli. Basebeletsi bohle ba molomo ba hypoglycemic ba nang le lijo tse sa reroang kapa ba sa lateleng mofuta oa moriana o khothalletsoang ba ka lebisa ho fokotseha ho hoholo hoa maemo a tsoekere ea mali le nts'etsopele ea boemo ba hypoglycemic. Ho noa tsoekere, liswiti, kapa lino tse tsoekere hangata ho thusa ho thibela ho itsoara pele ha hypoglycemic. Tabeng ea boemo bo tsoelang pele ba hypoglycemic, o lokela ho etela ngaka hang-hang.
Haeba o ikutloa o sa lokele (feberu, lekhopho, ho nyekelwa ke pelo) nakong ea kalafo le Glurenorm, o lokela ho etela ngaka hang-hang.
Haeba ho kula ho bakoa ke ho kula, o lokela ho emisa ho nka Glyurenorm, ho e sebelisa ka moriana o mong oa hypoglycemic kapa insulin.

Tšusumetso ho bokhoni ba ho khanna makoloi le litsamaiso tsa taolo
Nakong ea khetho ea moriana kapa phetoho ea lithethefatsi, o lokela ho qoba ho etsa lintho tse ka bang kotsi tse hlokang tlhokomelo e potlakileng le lebelo la maikutlo a psychomotor.

Fomu ea tokollo
Matlapa a 30 mg
Ho matlapa a 10 ka polasetiki ea "blist strip package" (blister) e tsoang PVC / Al.
Bakeng sa malepa a 3, 6 kapa a 12 a nang le litaelo tsa ho sebelisoa ka lebokoseng la karete.

Maemo a polokelo
Sebakeng se omileng, ka mocheso o sa feteng 25 ° C.
Qoba hole le bana!

Letsatsi la ho felloa ke nako
Lilemo tse 5
Se ke oa sebelisa kamora letsatsi la ho felloa ke nako le bontšitsoeng ka har'a sephutheloana.

Matsatsi a phomolo a tsoang litlolong tsa meriana
Ka lengolo la ngaka.

Moetsi
Beringer Ingelheim Ellas A.E., Greece Greece, 19003 Kings Avenue Pkanias Markopoulou, 5th km

Ofisi ea boemeli Moscow:
119049, Moscow, st. Donskaya 29/9, moaho 1.