Katleho ea Combogliz
Leqephe lena le fana ka lethathamo la lingoloa tsohle tsa Combogliz Prolong ho latela sebopeho sa bona le lipontšo tsa tšebeliso. Lethathamo la li-analogues tse theko e tlaase, hape u ka bapisa litheko libakeng tsa meriana.
- Analogue e theko e tlaase ka ho fetisisa ea Combogliz Prolong:Janumet
- Analogue e tummeng ka ho fetisisa ea Combogliz Prolong:Vipdomet
- Sehlopha sa ATX: Metformin hammoho le saxagliptin
- Motsoako o sebetsang: metformin, saxagliptin
| # | Sehlooho | Theko ho la Russia | Theko Ukraine |
|---|---|---|---|
| 1 | Janumet metformin, sitagliptin Analogue ponts'ong le mokhoa oa ts'ebeliso | 9 rub | 1 UAH |
| 2 | Glucovans glibenclamide, metformin Analogue ponts'ong le mokhoa oa ts'ebeliso | 34 rub | 8 UAH |
| 3 | Gluconorm Analogue ponts'ong le mokhoa oa ts'ebeliso | 45 rub | -- |
| 4 | Vipdomet metformin, alogliptin Analogue ponts'ong le mokhoa oa ts'ebeliso | 55 rub | 1750 UAH |
| 5 | Sinjardi empagliflozin, metformin hydrochloride Analogue ponts'ong le mokhoa oa ts'ebeliso | 240 rub | -- |
Ha u bala litšenyehelo Combogliz Prolong theko e fokolang e fumanoeng lenaneng la theko e fanoeng ke li-pharmacies e ile ea tsotelloa
| # | Sehlooho | Theko ho la Russia | Theko Ukraine |
|---|---|---|---|
| 1 | Vipdomet metformin, alogliptin Analogue ponts'ong le mokhoa oa ts'ebeliso | 55 rub | 1750 UAH |
| 2 | Gentadueto linagliptin, metformin Analogue ponts'ong le mokhoa oa ts'ebeliso | -- | -- |
| 3 | Janumet metformin, sitagliptin Analogue ponts'ong le mokhoa oa ts'ebeliso | 9 rub | 1 UAH |
| 4 | Glibomet glibenclamide, metformin Analogue ponts'ong le mokhoa oa ts'ebeliso | 257 rub | 101 UAH |
| 5 | Avandamet Analogue ponts'ong le mokhoa oa ts'ebeliso | -- | -- |
E fuoe lenane la lingaka tsa lithethefatsi e ipapisitse le lipalo-palo tsa litlhare tse kopiloeng ka ho fetisisa
Li-analog mabapi le sebopeho le pontšo ea ts'ebeliso
| Sehlooho | Theko ho la Russia | Theko Ukraine |
|---|---|---|
| Tripride glimepiride, metformin, pioglitazone | -- | 83 UAH |
| Comboglize XR metformin, saxagliptin | -- | 424 UAH |
Lethathamo le ka holimo la li-analogues tsa lithethefatsi, tse bonts'ang Tlhokahalo ea Combogliz, e loketse haholo hobane e na le sebopeho se tšoanang sa lintho tse sebetsang ebile e lumellana ho latela sesupo sa tšebeliso
Li-analoggs ka pontšo le mokhoa oa ts'ebeliso
| Sehlooho | Theko ho la Russia | Theko Ukraine |
|---|---|---|
| Amaryl M Limepiride Micronized, Metformin Hydrochloride | 856 rub | 40 UAH |
| Glibomet glibenclamide, metformin | 257 rub | 101 UAH |
| Glucovans glibenclamide, metformin | 34 rub | 8 UAH |
| Dianorm-m Glyclazide, Metformin | -- | 115 UAH |
| Dibizid-m glipizide, metformin | -- | 30 UAH |
| Douglimax glimepiride, metformin | -- | 44 UAH |
| Duotrol glibenclamide, metformin | -- | -- |
| Gluconorm | 45 rub | -- |
| Glibofor metformin hydrochloride, glibenclamide | -- | 16 UAH |
| Avandamet | -- | -- |
| Avandaglim | -- | -- |
| Janumet metformin, sitagliptin | 9 rub | 1 UAH |
| Velmetia metformin, sitagliptin | 6026 rub | -- |
| Galvus Met vildagliptin, metformin | 259 rub | 1195 UAH |
| Gentadueto linagliptin, metformin | -- | -- |
| Vipdomet metformin, alogliptin | 55 rub | 1750 UAH |
| Sinjardi empagliflozin, metformin hydrochloride | 240 rub | -- |
Moetso o fapaneng o kanna oa lumellana ho bonts'a mokhoa le mokhoa oa kopo
| Sehlooho | Theko ho la Russia | Theko Ukraine |
|---|---|---|
| Rosiglitazone e sebetsang, metformin hydrochloride | -- | -- |
| Bagomet Metformin | -- | 30 UAH |
| Glucofage metformin | 12 rub | 15 UAH |
| Glucophage xr metformin | -- | 50 UAH |
| Reduxin Met Metformin, Sibutramine | 20 rub | -- |
| Dianormet | -- | 19 UAH |
| Diaformin metformin | -- | 5 UAH |
| Metformin metformin | 13 rub | 12 UAH |
| Metformin sandoz metformin | -- | 13 UAH |
| Siofor | 208 rub | 27 UAH |
| Foromo metformin hydrochloride | -- | -- |
| Emnorm EP Metformin | -- | -- |
| Megifort Metformin | -- | 15 UAH |
| Metamine Metformin | -- | 20 UAH |
| Metamine SR Metformin | -- | 20 UAH |
| Metfogamma metformin | 256 rub | 17 UAH |
| Tefor metformin | -- | -- |
| Glycometer | -- | -- |
| Glycomet SR | -- | -- |
| Forthine | 37 rub | -- |
| Metformin Canon metformin, ovidone K 90, starch ea poone, crospovidone, magnesium stearate, talc | 26 rub | -- |
| Insuffor metformin hydrochloride | -- | 25 UAH |
| Metformin-teva metformin | 43 rub | 22 UAH |
| Diaformin SR metformin | -- | 18 UAH |
| Mepharmil Metformin | -- | 13 UAH |
| Metformin Farmland Metformin | -- | -- |
| Glibenclamide Glibenclamide | 30 rub | 7 UAH |
| Maninyl Glibenclamide | 54 rub | 37 UAH |
| Glibenclamide-Health Glibenclamide | -- | 12 UAH |
| Glyurenorm glycidone | 94 rub | 43 UAH |
| Bisogamma Glyclazide | 91 rub | 182 UAH |
| Glidiab Glyclazide | 100 rub | 170 UAH |
| Diabeteson MR | -- | 92 UAH |
| Diagnizide mr Gliclazide | -- | 15 UAH |
| Glidia MV Gliclazide | -- | -- |
| Glykinorm Gliclazide | -- | -- |
| Gliclazide Gliclazide | 231 rub | 44 UAH |
| Glyclazide 30 MV-Indar Glyclazide | -- | -- |
| Glyclazide-Health Gliclazide | -- | 36 UAH |
| Glioral Glyclazide | -- | -- |
| Lekola Gliclazide | -- | 14 UAH |
| Diazide MV Gliclazide | -- | 46 UAH |
| Osliklid Gliclazide | -- | 68 UAH |
| Diadeon gliclazide | -- | -- |
| Glyclazide MV Gliclazide | 4 rub | -- |
| Amaril | 27 rub | 4 UAH |
| Glemaz glimepiride | -- | -- |
| Glian glimepiride | -- | 77 UAH |
| Glimepiride Glyride | -- | 149 UAH |
| Glimepiride diapiride | -- | 23 UAH |
| Aletare | -- | 12 UAH |
| Glimax glimepiride | -- | 35 UAH |
| Glimepiride-Lugal glimepiride | -- | 69 UAH |
| Clay glimepiride | -- | 66 UAH |
| Diabrex glimepiride | -- | 142 UAH |
| Meglimide glimepiride | -- | -- |
| Melpamide Glimepiride | -- | 84 UAH |
| Perinel glimepiride | -- | -- |
| Glempid | -- | -- |
| Ke thabo | -- | -- |
| Glimepiride glimepiride | 27 rub | 42 UAH |
| Glimepiride-teva glimepiride | -- | 57 UAH |
| Glimepiride Canon glimepiride | 50 rub | -- |
| Glimepiride Pharmacyard glimepiride | -- | -- |
| Dimaril glimepiride | -- | 21 UAH |
| Glamepiride diamerid | 2 rub | -- |
| Voglibose Oxide | -- | 21 UAH |
| Glutazone pioglitazone | -- | 66 UAH |
| Dropia Sanovel pioglitazone | -- | -- |
| Januvia sitagliptin | 1369 rub | 277 UAH |
| Galvus vildagliptin | 245 rub | 895 UAH |
| Onglisa saxagliptin | 1472 rub | 48 UAH |
| Nesina alogliptin | -- | -- |
| Vipidia alogliptin | 350 rub | 1250 UAH |
| Trazhenta linagliptin | 89 rub | 1434 UAH |
| Lixumia lixisenatide | -- | 2498 UAH |
| Sebaka sa Guarem Guar | 9950 rub | 24 UAH |
| Insvada repaglinide | -- | -- |
| Novonorm Repaglinide | 30 rub | 90 UAH |
| Repodiab Repaglinide | -- | -- |
| Baeta Exenatide | 150 rub | 4600 UAH |
| Baeta Long Exenatide | 10248 rub | -- |
| Viktoza liraglutide | 8823 rub | 2900 UAH |
| Saxenda liraglutide | 1374 rub | 13773 UAH |
| Forksiga Dapagliflozin | -- | 18 UAH |
| Forsiga Dapagliflozin | 12 rub | 3200 UAH |
| Invocana canagliflozin | 13 rub | 3200 UAH |
| Jardins Empagliflozin | 222 rub | 566 UAH |
| Trulicity Dulaglutide | 115 rub | -- |
U ka fumana analogue e theko e tlaase ea moriana o theko e phahameng?
Ho fumana analogue e theko e phahameng ea moriana, mofuta oa generic kapa lebitso, pele ho tsohle re khothaletsa ho ela hloko sebopeho, e leng lintho le lipontšo tse tšoanang tse sebetsang. Metsoako e tšoanang ea lithethefatsi e tla bonts'a hore lithethefatsi li tsamaisana le lithethefatsi, li ka lekana meriana kapa li ka etsa meriana. Leha ho le joalo, u se ke oa lebala ka likarolo tse sa sebetseng tsa lithethefatsi tse tšoanang, tse ka amang polokeho le ts'ebetso. Se ke la lebala ka litaelo tsa lingaka, ho itlama ho ka lematsa bophelo ba hau, ka hona, etela ngaka ea hau kamehla pele u sebelisa meriana leha e le efe.
Combogliz Taelo ea ho eketsa
TLOTLISO Khoutu ea ATX: Lintho tse sebetsang Foromo ea litekanyetso Fomu ea tokollo, sebopeho le sephutheloana Combogliz Prolong ke lithethefatsi tsa hypoglycemic. E ngoletsoe lefu la tsoekere mofuteng oa bobeli. Bakeng sa kalafo ea lithethefatsi ho tlisa liphetho, kalafo e lokela ho kopantsoe le lijo le lipapali. Setlhare sena se na le likarolo tse peli tsa bohlokoa: metformin le saxagliptin. Ntle le bona, matlapa a na le likarolo tse kang magnesium stearate, sodium carmellose, hypromellose. Ka lebaka la metformin, mamello ea tsoekere e eketseha. Ntle le moo, ea thusa:
ts'ebeliso ea lithethefatsi
Katleho ea Combogliz
A10BD10 (Metformin hammoho le saxagliptin)
metformin (metformin) Rec.INN e ngolisitsoe ke WHO
saxagliptin (saxagliptin) Rec.INN e ngolisitsoe ke WHO
tab. ka tokollo e fetotsoeng. ho koahela lifilimi, 500 mg + 5 mg: 28 kapa 56 li-pcs.
Litafole tsa tokollo tse fetotsoeng, Tafole e kopantsoeng 1
metformin 500 mg
saxagliptin 5 mg
7 likhomphutha - marangrang (4) - lipakete tsa karete.Kopo
Karolo ea bobeli ke saxagliptin. E khothalletsa ho ntšoa ha lihormone tsa "incretin". Tsena tsa morao-rao li hlokahala ho susumetsa tlhahiso ea insulin. Tlas'a tšusumetso ea saxagliptin 'meleng, boemo ba insulin maling ha bo fokotsehe kapele haholo.
Likarolo tsa ts'ebeliso
Boithuto mabapi le tšebeliso ea li-hypoglycemic agents ho basali baimana le ba anyang matsoele ha lia etsoa. Tšebeliso ea lithethefatsi ha e khothalletsoe mekhahlelong ena. Moriana ona o kopantsoe le ho bana ba ka tlase ho lilemo tse 18.
Ts'ebeliso ea moriana botsofaling e bakoa ke likarolo tse ling. Ts'ebetso e fokotsehileng ea ts'ebetso ea moroto hona joale e hloka tlhokomeliso kalafong. Sena se bakoa ke taba ea hore karolo e nyane ea likarolo tsa moriana (saxagliptin le metformin) li etsoa ke liphio.
Ho khothalletsoa ho nka ka hloko moemeli enoa oa hypoglycemic ho ba nang le lefu la pancreatitis. Sena se bakoa ke khaello ea tlhaiso-leseling ea lipalo mabapi le kamano lipakeng tsa tšebeliso ea lithethefatsi le monyetla oa ho holisa lefu lena.
Lokolla liforomo
Sesebelisoa se fumaneha ka mokhoa oa matlapa. Li shebahala joaloka li-capsules ka ponahalo ebile li koahetsoe ka filimi e khethehileng ka holimo. 'Mala oa eona o latela litekanyetso tsa moriana. 'Mala o mosehla o bontša se ka har'a 1000 mg ea metformin hammoho le saxagliptin (ka bongata ba 2 mg mg). Moriti o pinki oa letlapa o bontša sebopeho se latelang: 1000 mg ea metformin le 5 mg ea saxagliptin. Ha capsule e le kofi e bobebe ka 'mala, letlapa le na le 500 mg ea metformin le 5 mg ea saxagliptin. Ka pakete e nang le lithupa tse 7 tsa matlapa a 7. Ho paka ka karete ho ka ba le lilakane tse 4 kapa tse 8. Sejana se seng le se seng se na le litaelo tsa hore li sebelisoe.
Litaelo tsa ho sebelisoa
Combogliz Prolong e nkuoa nako e le 1 ka letsatsi. Nako e nepahetseng ke lijo tsa ho qetela. Moriana o lokela ho nooa ka botlalo, ntle le ho arolelana.
E 'ngoe ea likarolo tsa lithethefatsi - metformin e hlahisoa haholo ke liphio, kahoo ho hlokahala tlhahlobo ea pele. Sena se bohlokoa molemong oa ho qhela ho ba teng ha ho sebetsoa ke a masapo kapa mekhoa e meng ea ts'ebetso ea liphio.
Tabeng ea ts'ebetso e tlang ea ho buuoa, emisa tšebeliso ea lithethefatsi. Mokhelo ke ho qhekella ho sa amaneng le ho fokotsa phepo e nepahetseng le phepelo ea metsi. Kamora ho buuoa, ts'ebeliso ea lithethefatsi e boetse e qalella ha ts'ebetso e tloaelehileng ea menoana e khutlisoa mme mokuli a khona ho e sebelisa ka molomo.
Contraindication
Maemong a mang, tšebeliso ea moriana oa Combogliz Prolong e thibetsoe. Maemo ana a kenyelletsa lintlha tse latelang:
- ho ba teng ha kutloisiso e matla ea motho ka mong ho likarolo tse kenang tsa sehlahisoa,
- tlhahlobo ea maikutlo a amanang le kutloisiso e itseng ho li-inhibitors tsa DPP-4 ka mokhoa oa ho tsitsipana kapa angioedema,
- boteng ba lefu la tsoekere le mofuta oa pele, hobane ha ho na tlhahiso-leseling mabapi le tšebeliso ea lithethefatsi bakeng sa lefu lena.
- e sebelisoa ka thata ka insulin,
- mafu a tlhaho, mohlala, ho se mamelle ha ntho e joalo ka galactose,
- ho ima le ho nyekeloa,
- lilemo ho fihlela lilemo tse 18,
- methapo ea ts'ebetso ea liphio, moo matšoao a serum creatinine a leng ≥1.5 mg / dL (bakeng sa banna), ≥1.4 mg / dL (bakeng sa basali), kapa tumello ea tlhahiso eaine e theotsoe.
- ts'ebetso ea methapo ea methapo e bakoang ke methapo ea pelo kapa methapo ea mali,
- mafu a hlobaetsang a amanang le monyetla oa ts'ebetso ea ts'ebetso ea methapo: ts'ebetso ea ho omella ka lebaka la ho hlatsa kapa setulo se sa thekeseleng, feberu, mafu a bakoang ke ts'oaetso, ho senyeha ha metabolism ea oksijene,
- tlolo ea molao-motheo oa acid ea mefuta e fapaneng,
- boteng ba maloetse a kotsi bakeng sa tlolo ea phepelo ea oksijene liseleng (mohlala, ka mefuta e fapaneng ea ho haella, infraction ea myocardial e mpe),
- ho buuoa kapa ho tsoa likotsi tse hlokang ho tsamaisoa ha insulin ka nako e le 'ngoe,
- lefu la sebete
- boteng ba nalane ea ho lemalla joala bo sa feleng kapa chefo e matla le ntho e nang le joala,
- ho hlaha hoa lactic acidosis,
- matsatsi a mabeli pele le kamora thuto ba sebelisa seea-le-moea kapa x-ray,
- Lijo tse nang le khalori e tlase (Dosage
Palo ea moriana eo mokuli a lokelang ho e nka e khethoa ke ngaka e tlang kamora ho etsa liteko tsohle tse hlokahalang. Haeba phekolo e etsoa ka tokisetso ea likarolo tse peli e kenyelletsang lintho tse kang saxagliptin le metformin, joale palo ea pele ho tsona ke 5 mg hang ka letsatsi.
Tabeng ena, metformin e lokela ho nooa pele ho 500 mg hang ka letsatsi. Butle-butle eketsa palo e le hore u fokotse kotsi ea litlamorao tse mpe tse amanang le tsamaiso ea mala. Boholo (ka letsatsi) bo nkuoa e le litekanyetso tse latelang: saxagliptin - 5 mg, bakeng sa metformin - 2000 mg.
Ts'ebeliso e ts'oanang ea li-inhibitors tse nang le matla tsa CYP3A4 / 5 isoenzymes (mohlala, ketoconazole) e hloka phokotso ea tekanyetso ea saxagliptin ho isa ho 2,5 mg hang ka letsatsi.
Litlamorao
Ka linako tse ling, haeba moriana o sebelisoa hampe, mokuli a ka khathatsoa ke maikutlo a fosahetseng. Tafole e bonts'a litlamorao tse atileng haholo ha u sebelisa Combogliz Prolong.
Liphello tse mpe (kalafo ka e 'ngoe ea mekhoa le kalafo e eketsehileng).
- hlooho e bohloko
- mafu a tšoaetsanoang ka sebopeho sa genitourinary,
- bohloko ba ka mpeng le ho hlatsa,
- thrombocytopenia
- lymphocytopenia (e nang le tšebeliso e telele),
- ho theola boemo ba vithamine B12 'meleng (ka tšebeliso e telele)
- litulo tse otlolohileng
- tsoekere e tlase ea mali
- nasopharyngitis,
- lekhopho la letlalo la mofuta oa uritisaria,
- gastroenteritis
- ho ruruha sefahlehong,
- pancreatitis e hlobaetsang.
- lets'ollo
- maikutlo a ho nyekeloa
- tlhahiso e ntlafalitsoeng ea khase,
- ho hlatsa
- pathology ea litatso tsa tatso.
Har'a mekhoa ea bohlokoa ea moriana o mong le o mong, ho kenyelletsa Combogliz Prolong, khetholla katleho le litšenyehelo. E latelang e khethoa ke mokhoa oa tokollo. Theko ea lithethefatsi e fapana ho latela meeli e latelang:
- litekanyetso tsa 1000 mg le 5 mg (boteng ba litafole tse 28 ka pakete): ho tloha ho 2730 ho isa ho li-ruble tse 3250,
- litekanyetso tsa 1000 mg le 2,5 mg (boteng ba litafole tse 56 ka pakete): ho tloha ho 2600 ho isa ho 3130 li-ruble.
Litsenyehelo tse phahameng tsa lithethefatsi li bakoa ke taba ea hore e kenelletse naheng e 'ngoe. Naha e etsang lihlahisoa ke Great Britain.
Maemong a mang, ka kalafo e nang le Combogliz Prolong, ho ba le litla-morao tse mpe tsa 'mele. Sena se kanna sa bakoa ke mamello ho likarolo tse teng, ho ba teng ha litlolo. Maemong a joalo, ho hlokahala hore ho lokisoe mofuta oa kalafo. Ke ngaka feela e ka khethang sethethefatsi se seng motheong oa data ea tlhahlobo ea mokuli.
Har'a lipapiso tsa lithethefatsi Combogliz Prolong khetha e 'ngoe ea litokisetso tsa likarolo tse ngata kapa karolo e le' ngoe. Sehlopha sa pele se emeloa ke lithethefatsi tse latelang:
- Janumet - sethethefatsi se nang le likarolo tse peli tsa sehlooho: metfomin le saxagliptin. Har'a melemo ea eona, e ka sehloohong ke monyetla oa ho sebelisa lithethefatsi hammoho le kalafo ea insulin le li-agonists tsa gamma receptor. Litsenyehelo tsa lithethefatsi li tloha ho li-ruble tse likete tse tharo.
- Galvus Met e kenyelletsa vildagliptin le metfomin. Leha ho na le phapang e itseng sebopeng, moriana, joalo ka Combogliz Prolong, o na le phello ea hypoglycemic. Ka nako e ts'oanang, kalafo ea insulin, kalafo e nang le sulfonylureas, metformin e ka etsoa. Ka karolelano, litšenyehelo tsa sephutheloana sa matlapa a 30 ke li-ruble tse likete li le 'ngoe.
- Comboglize Xr - sethethefatsi se nang le phello ea hypoglycemic. Sena se etsoa ke litaba tsa metformin le saxagliptin. Tekanyetso ea lithethefatsi e khethoa ke ngaka ka mor'a ho hlahloba mokuli. Har'a lintho tse hanyetsanang le lithethefatsi, nako ea kemaro, ho nyeka, lilemo tsa bana ho fihlela lilemo tse 18 lia khetholoha. Litlamorao tse mpe le tse mpe tsa ho nka Comboglyz Xr li tšoana le tse etsahalang kamora ho sebelisa Combogliz Prolong. Theko e tloaelehileng ea pakete ea meriana (ho tsoa matlapeng a 28) ke li-ruble tse 1,600.
- Glimecomb - lithethefatsi tse kopaneng tsa hypoglycemic. Sebopeho sa moriana se kenyelletsa likarolo tse peli tse sebetsang: metformin hydrochloride le gliclazide. Litekanyetso li itšetleha ka tsoekere ea mali. Nakong ea kalafo, phepo e tloaelehileng e lokela ho fanoa. Lijo li lokela ho kenyelletsa lik'habohaedreite tse nyane. Ka nako e tšoanang, lijo tsa hoseng ke moetlo o tlamang hoseng. Theko e ipapisitse le tekanyetso le mofuta oa moriana. Ka karolelano, litšenyehelo li tsoa ho li-ruble tse 246. ho fihlela ho li-ruble tse 497.
- Avandamet - Ena ke moemeli e mong oa hypoglycemic. Sebopeho sa moriana se kenyelletsa lintho tse sebetsang tse kang rosiglitazone (ka mokhoa oa maleate) le metformin hydrochloride. Litho tsena li lumellana le ketso ea e mong le e mong, li fana ka phokotso ea tsoekere ea mali. Ts'ebeliso ea sethethefatsi sena ha e na tšebeliso ea lijo. Le ha ho le joalo, tšebeliso ea lithethefatsi nakong ea lijo kapa ka mor'a ho ja e fokotsa kotsi ea ho hlaha. Litsenyehelo tsa litlhare tse fapaneng li tloha ho 1398 ho isa ho 1526 li-ruble.
Har'a li-analogu tsa karolo e le 'ngoe, ho na le:
- Kholiso ea Gliformin - sesebelisoa se nang le ntho e le 'ngoe - metformin. Moriana ona o sebelisoa ho monotherapy. Empa e ka sebelisoa hammoho, ka mohlala, ka insulin kapa lithethefatsi tse ling tse theolelang tsoekere. Litšenyehelo li tloha ho li-ruble tse 224 ho isa ho tse 508.
- Glucophage. Motheo oa sethethefatsi ke metformin. E ka sebelisoa kalafo e kopaneng e sebelisa insulin. Theko e fapana ho tloha ho li-ruble tse 90 ho isa ho tse 770, ho latela tekanyetso ea moriana.
- Onglisa E na le karolo e le 'ngoe e sebetsang - saxagliptin ka mokhoa oa hydrochloride. E sebelisoa ka bobeli ka monotherapy hape e le karolo ea kalafo e rarahaneng. Tsamaiso e ts'oanang ea "insulin" e hatelloa. Litsenyehelo tsa litlhare tse fapaneng li tloha ho 1594 ho isa ho 2195 li-ruble.
- Siofor. Ntho e sebetsang ea lithethefatsi ke metformin hydrochloride. Ka lebaka la ho fokotseha ha takatso ea lijo, moriana o thusa ho theola boima ba 'mele. Theko ea Siofor ka kakaretso e tsoa ho li-ruble tse 238 ho isa ho tse 293.
Bongata
Ho sebelisa lithethefatsi tse ngata ho ka khoneha ka tšebeliso e mpe kapa tšebeliso nako e telele. Ka tšebeliso ea nako e telele ea saxagliptin le tlhaiso ea matšoao a overdose, hemodialysis e laetsoe. Ntle le moo, kalafo ea matšoao e etsoa.
Maemong a mangata, ho ba le overdose ea metformin. Sena se bontšoa ke hypoglycemia le lactic acidosis, e atisang ho tsamaisana le ts'ebetso ea mokokotlo oa mokokotlo. Boemo ba ho qetela, lactic acidosis, ke bokuli bo tebileng ba metabolic. E kopantsoe le keketseho ea khatello ea metformin maling maling a fetang 5 μg / ml. Har'a matšoao a lactic acidosis ke:
- mokhathala,
- ho hloleha ho phefumoloha
- bohloko bo ka mpeng
- ho theola khatello ea mali
- ho fokotsa mocheso oa 'mele
- bohloko ba mesifa
- khahlanong le bradyarrhythmia.
Lactic acidosis e ka ba le imperceptibly, ka hona, tlhokomelo e khethehileng e lokela ho lefshoa ho hlaha ha matšoao a se nang letho. Ponahalo ea letšoao leha e le lefe la malaise e hloka ho ikopanya le ngaka. Haeba liketsahalo tse ka holimo li fumanoa, lactic acidosis e etsoa:
- taolo ea li-electrolyte tsa serum,
- ho ithuta ka 'mele oa ketone,
- Teko ea tsoekere ea mali,
- tlhaiso ea mali ea pH
- taolo ea boemo ba lactate,
- thuto ea metformin litekong tsa mali.
Bakuli ba sebelisang metformin ho monotherapy kapa ka kalafo e rarahaneng ba lokela ho hopola hore lactic acidosis e lokela ho phekoloa sepetlele. Maemong a sa tsotelloeng, ha ho se na tlhokomelo ea bongaka e tlang ka nako, pherekano e etsahala, e lebisang ho holiseng komello. Har'a matšoao a hypoglycemia, ho na le:
- mokhathala
- ponahalo ea letsoalo,
- boemo ba ho akheha
- ho otsela
- ho hlaha hoa maikutlo a fosahetseng a sa feleng.
E le ho betla metformin, hemodialysis e etsoa. Boemong bofe kapa bofe, ha u sebelisa lithethefatsi, ho hlokahala ho hlahloba boemo ba mokuli. Ho arabela ka tsela efe kapa efe e mpe ho lokela ho tlaleheloa ngaka ea hau.
Morero oa lithethefatsi Combogliz Prolong, litlhahlobo tse ntle tseo boholo ba tsona bo sebetsang, li etsoa ke ngaka kamora tlhahlobo e hlokahalang. Se ke oa iphekola. Tekanyetso le monyetla oa ho nka moriana o ka khethoa feela ke setsebi. Ho seng joalo, ho na le kotsi ea ho ba le maikutlo a mabe kapa matšoao a botahoa bo feteletseng. Ka lefu la tsoekere la mofuta oa 2, u ka phela hamonate, ntho ea bohlokoa ke ho laola boemo ba hau le ho etela ngaka.
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