Desoxinate - litlhaloso tsa lithethefatsi, litaelo tsa tšebeliso, litlhahlobo

Sehloohong sena, o ka bala litaelo tsa ho sebelisa lithethefatsi Desoxinate. E fana ka maikutlo a tsoang ho baeti sebakeng sena - bareki ba meriana ena, hammoho le maikutlo a litsebi tsa bongaka mabapi le tšebeliso ea Deoxinat ts'ebetsong ea bona. Kopo e kholo ke ho kenyelletsa maikutlo a hau ka sethethefatsi sena: moriana o thusitseng kapa o sa thusa ho felisa lefu lena, hore na ho bile le mathata afe kapa afe, mme mohlomong a sa phatlalatsoe ke moetsi ho phatlalatso. Li-analogue tsa Deoxinate moo ho nang le li-analogues tsa sebopeho tse fumanehang. Sebelisa bakeng sa kalafo ea ulcers tsa trophic, ho chesa, lefu la radiation, leukopenia, thibelo ea ho lahla ho fetela ho batho ba baholo, bana, esita le nakong ea kemero le ho beleha. Sebopeho sa moriana.

Desoxinate - Sethethefatsi se sebetsanang le ho itšireletsa mafung le seriti. E na le phello ea phekolo ho lcerative necrotic vidion tsa letlalo le li-membrane tsa mucous tsa localization tse fapaneng. Ts'ebeliso ea moriana oa lithethefatsi ka mokhoa oa ho roala, lits'ebetso le li-rinses li na le phello ea analgesic, e fokotsa lipontšo tsa ts'oaetso ea ho ruruha, e etsa hore kholo ea granulations le epithelium. Ka ts'ebetso ea ts'ehetso sethaleng sa nchafatso, e lebisa ho pholiso e potlakileng. Deoxinate e thusa ho eketsa ho kenella ha mesebetsi ea matsoho marang-rang a tukang, hammoho le lisebelisoa tsa bongaka tse sebelisoang ka polasetiki ea litšila sebakeng se seholo sa maxillofacial. Ts'ebeliso ea Deoxinate ha e tsamaellane le maikutlo a nang le chefo le a kulang.

Sebopeho

Sodium deoxyribonucleate + excipients.

Pharmacokinetika

Ha e sebelisoa ka mokhoa o hlophisitsoeng, deoxinate e kenella mme e ajoa ka litho le lisele ka ho ba le seabo tseleng ea endolymphatic. Mokhahlelong oa ts'ebeliso e matla ea lithethefatsi maling, ho abuoa hape pakeng tsa plasma le lisele tsa mali, hammoho le metabolism le excretion. Desoxinate e tšelisoa 'meleng ho ea ho xanthine, hypoxanthine, beta-alanine, asetiki, propionic le uric acid, e hlahisoang ke liphio le karolo e itseng ka ts'ebetso ea mpa.

Matšoao

• bokuli ba radiation, ho kenyelletsa le dermatitis ea radiation, ulcitis ea mantlha le ea morao-rao, lefu la radiation pharyngeal syndrome,
• ho chesoa ha letlalo le mocheso oa likhato tse 2-3,
• liso tsa trophic, ho kenyeletsoa le methapo ea varicose ea lipheletso tse tlase,
• tlolo ea botshepehi ba membrane ea mucous ea molomo, nko, botšehali, rectum,
• Litlhoko tsa ho hlaba kahare ho molomo le letlalong.
• mathata a amanang le kalafo ea cytostatic (stomatitis, pharyngoesophagitis, gingivitis, uvulitis, enterocolitis, vulvovaginitis, paraproctitis, leukopenia),
• Thibelo ea ho se laeloe ho fetisoa ha ho hlophisoa ha li-tishu bakeng sa auto- kapa allotransplantation le nakong ea ts'ebetso ea transplant,
• Nako ea ho hlaphoheloa kamora mafu a tebileng a tšoaetsanoang le a mang.

Lokolla liforomo

Tharollo bakeng sa tsamaiso ea methapo le methapo ea methapo ea 0,5% ho li-ampoules tsa 5 ml le 10 ml.

Tharollo bakeng sa ts'ebeliso ea kantle le ea lehae ea 0.25% ho 5 ml, 10 ml, 20 ml le likopi tsa 50 ml.

Litaelo tsa mokhoa oa ho sebelisoa le oa litekanyetso

Sethethefatsi se laetsoe bana ho tloha ka letsatsi la pele la bophelo le batho ba baholo.

Bakeng sa kalafo ea maqeba a letlalo, kenya masela ka tharollo, a nkeloe makhetlo a 3-4 ka letsatsi.

Ha ho ruruha mucosa ea molomo, li-rinses li etsoa ka tharollo ea Deoxinate (makhetlo a 4 ka letsatsi, 5-15 ml, e lateloe ke ho koenya).

Ka hara botshehadi, Deoxinate e tsamaisoa ka swab, ho rectum ka enema (20-50 ml).

Nako ea karolelano ea kalafo ke ho nyamela ho sa feleng hoa matšoao a ho ruruha kapa ho phumula ha letlalo le lera la ka mpeng (matsatsi a 4-10).

Intramuscularly (butle-butle) kapa ka mokhoa o ikhethileng, Deoxinate e fuoa batho ba baholo le bana hang - 15 ml ea tharollo ea 0.5% (75 mg ea ntho e sebetsang). Tsamaiso e phetoang nakong ea mekhahlelo e latelang ea kalafo ea chemotherapy, radiation kapa chemoradiation ho bakuli ba mofets'e e lumelletsoe. Bakeng sa kalafo ea lefu la radiation le a hlobaetsang - ha ho pele ho feta lihora tse 24 ka mor'a ho pepesetsoa mahlo.

Litla-morao

• hyperthermia ea nako e khuts'oane (lihora tse 2-4, kamora lihora tse 3 ho ea ho tšebetso) ho tloha ho linomoro tse tlase ho isa linomong tsa febrile,
• ka tsamaiso ea methapo ea methapo - bohloko bo bokhutšoaane sebakeng sa ente, ha bo hloke kalafo,
• ts'ebeliso ea li-topical ha e bake litla-morao.

Contraindication

• hypersensitivity ho sodium deoxyribonucleate kapa motsoako ofe kapa ofe oa lithethefatsi.

Bokhachane le pelehi

Moriana o lumelloa hore o sebelisoe nakong ea kemaro le ho lactation.

Sebelisa ho bana

Abela bana ho tloha letsatsi la pele la bophelo.

Sebelisa ho bakuli ba tsofetseng

Bakuli ba tsofetseng ha ba hloke phetoho ea litekanyetso.

Litaelo tse khethehileng

Intravenous tsamaiso ea tharollo ea Deoxinate ha e lumelloe.

Lithethefatsi ha li na thuso ka mekhoa e mebe haholo ea ts'enyo, ho teba ho tebileng ha necrosis, ho amahanngoa le boemo ba 4 ba maemo.

Ho sebelisana le lithethefatsi

Deoxinate ha e tsamaisane le mafura a thehiloeng ho mafura le hydrogen peroxide.

Likhakanyo tsa lithethefatsi Deoxinate

Analogue ea sebopeho sa ntho e sebetsang:

• Derinat
• Sodium deoxyribonucleate,
• Panagen.

Likhakanyo tsa lithethefatsi Deoxinate ho ea ka sehlopha sa litheko tsa bongaka (li-regenerants le tse iphetetsang):

• Adgelon
• Actovegin,
• Aloe draina
• Alginatol,
• Apilak
• Balarpan
• Bostakovsky Balm,
• Bepanten
• Lipalesa tsa lehlabathe tse jang
• Beta carotene
• Beteltsil
• Biartrin,
• Likokoana-hloko
• Vinylin,
• Vitanorm,
• Hyposol N,
• Gumizol,
• D-Panthenol
• Dalargin
• Dexpanthenol,
• Immeran
• Intragel
• Inflamistine
• Cambiogenplasmid,
• Korneregel,
• Ximedon
• Curiosin,
• Rhizomes of the king
• Balsamic liniment (ho ea ka Vishnevsky),
• Methyluracil
• Meturacol,
• Moreal More,
• Sodium deoxyribonucleate,
• Oli ea leoatleng
• Bosholu
• Panagen
• Panthenol
• Pantoderm
• Pentoxyl
• Mafura a mafura
• Semela sa joala,
• Polyvinylinine
• Polyvinox
• Prostopin
• Retinalamine,
• Rumalon
• Sinoart
• Solcoseryl,
• Stellanin
• Stizamet
• Nthabiseng,
• Tykveol
• Pumpkinol
• Ulcep
• Phytostimulin,
• Roseity oli,
• Ebermin,
• Eberprot P,
• Eplan
• Etaden.

E hlahlojoa ke ngaka e buoang

Ke sebelisa tharollo ea Deoxinat haholo bakeng sa kalafo ea lehae ea liphoso tse kulang hantle ho bakuli ba nang le methapo ea varicose e lipakeng tse tlase le liso tsa khatello ho bakuli ba robetseng liphateng. Liaparo li tlameha ho fetoloa khafetsa, empa mekhoa e metle e hlokometsoe bekeng ea pele ea kalafo. Metsoako e metala e hlaha, bokaholimo ba liso tsa hau bo qala ho epithelize. Deoxinate e boetse e sebetsa hantle kalafo ea ho chesoa. Ntho ea bohlokoa ka ho fetisisa ke hore, ts'ebetsong ea ka, ha ho na bakuli ba bileng le karabelo ea mofuta ona oa lithethefatsi.

Fomu ea tokollo

ente 0.5%, ampoule 5 ml le lebokose le leholo la bokete (lebokose) 10,

Sebopeho
1 ml ea tharollo bakeng sa ts'ebeliso ea kantle e na le 0,0025 g ea sodium deoxyribonucleate e tsoang lebese la sturgeon, ka libotlolo tsa khalase tsa 50 ml, ka lebokoseng la karete ea 1.

1 ml ea tharollo ea ente - 0,005 g, ka har'a ampoule ea 5 ml (e felletseng ka thipa e ngata), ka lebokoseng la karete e 10 li-pcs.

Lithethefatsi tse tšoanang:

• Derinat (Derinat) Tharollo ea entetso
• Solcoseryl Dental Adhesive paste
• Solcoseryl (Solcoseryl) Setlolo bakeng sa ts'ebeliso ea kantle
• Meturacolum (Spongia "Meturacolum") seponche se phahameng
• Setlolo sa Iruxol (Iruxol)
• Tharollo ea Derinat (Derinat) Tharollo ea ts'ebeliso ea lehae
• Galenofillipt (Tincture)
• Amprovisol (Amprovisol) Aerosol
• Lintaderm (Naphtaderm) Liniment
• Setlolo sa Proctosan (Proctosan) bakeng sa ts'ebeliso ea lehae le kantle

** Tataiso ea ho fana ka litlhare ke bakeng sa tlhahisoleseling. Bakeng sa tlhaiso-leseling e batsi, ka kopo sheba litlhaloso tsa moetsi. Se ke oa ikoetlisa, pele u qala ts'ebeliso ea lithethefatsi Deoxinate, o lokela ho etela ngaka. EUROLAB ha e ikarabelle bakeng sa litlamorao tse bakoang ke ts'ebeliso ea tlhaiso-leseling e hatisitsoeng portal. Tlhahiso-leseling efe kapa efe e teng sebakeng sa marang-rang ha e nke sebaka sa keletso ea ngaka ebile e ke ke ea fana ka tiiso ea litlamorao tsa lithethefatsi.

U khahloa ke Deoxinate? Na u batla ho tseba lintlha tse qaqileng kapa ho hlokahala hore u ee ngakeng? Kapa o hloka tlhahlobo? O ka khona etsa tumellano le ngaka - Euro tleliniki lab kamehla ts'ebetsong ea hau! Lingaka tse ntle li tla u hlahloba, ho u eletsa, ho fana ka thuso e hlokahalang le ho etsa tlhahlobo ea mafu. U ka khona letsetsa ngaka lapeng. Clinic Euro lab e buletsoe nako eohle.

** Hlokomela! Tlhahisoleseling e hlahisitsoeng tataisong ena ea meriana e etselitsoe litsebi tsa bongaka 'me ha ea lokela ho ba mabaka a ho itlhalosa. Tlhaloso ea lithethefatsi Deoxinate e fanoa bakeng sa tlhaiso-leseling ebile ha ea rereloa ho fana ka kalafo ntle le ho nka karolo ha ngaka. Bakuli ba hloka boeletsi bo ikhethang!

Haeba o ntse o thahasella meriana le litlhare tse ling, litlhaloso tsa bona le litaelo tsa tšebeliso, tlhaiso-leseling mabapi le sebopeho le mofuta oa tokollo, matšoao a ts'ebeliso le litlamorao, mekhoa ea ts'ebeliso, litheko le litlhahlobo tsa meriana, kapa na u na le lipotso tse ling le litlhahiso - re ngolle, ka sebele re tla leka ho u thusa.

Matšoao a ho sebelisoa

Thibelo ea mokokotlo oa masapo a hematopoiesis (leukopenia, thrombocytopenia) ho bakuli ba nang le mofetše ka lebaka la cytostatics (mono- kapa polychemotherapy) kapa chemoradiotherapy e kopaneng.

Desoxinate (ea boikhethelo): thibelo ea myelodepression pele ho qaleho ea potoloho ea chemotherapy, haholoholo khafetsa, nakong le kamora eona, ho pepeseha mahlaseli a kotsi a ionizing methating e bakang tsoelo-pele ea bokuli ba radiation II-III.

Derinat (ea boikhethelo): stomatitis, ulcer le seso sa duodenal, gastroduodenitis, lefu la pelo ea ischemic, mafu a sa foleng a ischemic a lijana tsa lits'ebetso tse tlase (II-III art., Ulcic ulcers, maqeba a sa phekolehe, lits'ebetso tsa purulent-septic, ho chesa, serame , ho lokisoa ha lisele bakeng sa auto- le allotransplantation le nakong ea ts'ebetso ea ts'ebetso ea boteng, prostatitis, vaginitis, endometritis, ho hloka thari, ho hloka matla ho bakoang ke ts'oaetso e sa foleng, COPD, ts'ebetsong ea bongaka e sebelisang ts'ebetso ea pelehi le ea pelehi.

Mokhoa oa ho sebelisa: litekanyetso le kalafo

Pele ho tsamaiso, tharollo e futhumetse mocheso oa 'mele.

Derinat: in / m (butle, ka nako ea metsotso e 1-2) ka nako ea lihora tse 24-72.

Batho ba baholo - 5 ml (ntho e omeletseng ea 75 mg). Ka lefu la pelo le coronary ea methapo ea methapo e tlase, ho kenngoa liente ka 5-10 (lethal dose ka karo ea kalafo ke 375-750 mg) nako ea matsatsi a 1-3.

Ka peptic ulcer ea ka mpeng le duodenum - ente tse 5 (lethal dose ka thupelo ea kalafo - 375 mg) nako e telele ea lihora tse 48.

Ho lefu la gynecology le andrology, tekanyetso ea thupelo ke liente tse 10 (lethal dose ka karo ea kalafo ke 750 mg) nako ea lihora tse 24-48.

Ho susumetsa leukopoiesis, i / m e fanoa ka 75 mg ka letsatsi le leng le le leng la 2-4, thupelo ea kalafo ke liente tsa 2-10 (lethal dose ea litekanyetso ke 150-750 mg). Ha maqeba a radiation a beoa ka tekanyetso e le 'ngoe letsatsi le letsatsi, tekanyetso ea thupelo ke 375-750 mg.

Bana ba ka tlase ho lilemo tse peli ba fuoa tekanyetso e le 'ngoe ea 0.5 ml (7.5 mg ka mokhoa o ommeng), ba lilemo tse 2-10 - 0,5 ml bakeng sa selemo se seng le se seng sa bophelo.

Desoxinate: in / m (butle) kapa s / c, batho ba baholo le bana hang - 15 ml ea tharollo ea 0.5% (75 mg ea ntho e sebetsang). Tsamaiso e phetoang nakong ea mekhahlelo e latelang ea kalafo ea chemotherapy, radiation kapa chemoradiation ho bakuli ba mofets'e e lumelletsoe. Bakeng sa kalafo ea lefu la radiation le a hlobaetsang - ha ho pele ho feta lihora tse 24 ka mor'a ho pepesetsoa mahlo.

Ketso ea pharmacological

E na le phello ea immunomodulatory maemong a cellular le a tlotlollang. E kenya ts'oaetso ea antiviral, antifungal le antimicrobial.

E na le ts'ebetso ea radioprotective, e tsosa tsoelo-pele: e potlakisa pholiso ea maqeba le ulcerative necrotic lesions ea letlalo le membrane ea mucous, e nolofalletsa kholo ea granulations le epithelium.

E na le litlamorao tse khahlanong le ho ruruha, li-antitumor le tse fokolang tsa anticoagulant, e lokisa maemo a lisele le litho tse nang le lefu la methapo ea methapo.

Regulates hematopoiesis (e nolofatsa palo ea leukocytes, granulocytes, phagocytes, lymphocyte, liplatelete).

E sebetsa hantle ho lefu la mahlaseli a kotsi a radiation II. le ka maemo a hypo- le aplasiki a hematopoietic system a bakoang ke radiation kapa polychemotherapy ea mofets'e.

Ente e le 'ngoe ea intramuscular nakong ea lihora tsa pele tse 24 kamora phello e felletseng ea ionizing radiation' meleng e nolofalletsa ho kula ha lefu la radiation, ho potlakisa ho qaleha le sekhahla sa ho khutlisetsa lisele mokokotlong oa masapo, hammoho le myeloid, lymphoid le platelet hematopoiesis. E eketsa menyetla ea liphetho tse ntle tsa bokuli ba radiation.

Khothatso ea leukopoiesis kamora ho entoa e le 'ngoe ea i / m e bonoa ho bakuli ba nang le mofetše ka leukopenia III tbsp. le bonono bo sokelang bophelo ba IV. (febrile neutropenia) e bakoang ke ts'ebeliso ea polychemotherapy kapa polychemotherapy e kopaneng. Pele ho tsohle, ho na le keketseho ea makhetlo a 5-7 ka har'a mali a potoloho ea palo e felletseng ea li-granulocytes, ka nako e ts'oanang, keketseho ea palo e felletseng ea li-lymphocyte le ho tloaeleha ha litaba tsa liplatelete maling a potoloho le thrombocytopenia ea degree ea I-IV ea tšimoloho e tšoanang e boletsoe.

Tabeng ea maloetse a ischemic a lipheletso tse tlase tse bakoang ke atherosulinosis le arteritis (ho kenyeletsa le bakuli ba nang le lefu la tsoekere), e eketsa mamello ea ho ikoetlisa ha ho tsamaea, ho tlosa bohloko mesifa ea namane, ho thibela bata le ho bata ha maoto, ho eketsa matla a phallo ea mali libakeng tse tlase, e hlohlelletsang pholiso ea li-ulcous trophic ulcers, ho bakuli ba bang e lebisa ho hatseng ka boomo lipalfine tsa necrotic tsa menoana, e thibelang ho kenella ha ho buuoa.

E le karolo ea mamello e rarahaneng, lefu la pelo le matla le ntlafatsa ts'ebetso ea pelo, le thibela lefu la myocyte, le ntlafatsa methapo e mengata mesifa ea pelo, le ho eketsa mamello.

E susumetsa ho nchafala hoa ulcers kahare ho tšilo ea lijo, e sitisa kholo ea Helicobacter pylori.

E eketsa ho kenella ha mesebetsi ea matsoho nakong ea ho fetoloa ha letlalo le eardrum, e holisa methapo e ka pele ea litho tsa ka hare.

E fokotsa sekhahla sa tumello mme e eketsa phello ea kalafo ea cytostatics kapa chemoradiotherapy. Ha e bake lehlakore le sa lebelloang kapa le liehang ho hlaha le litlamorao tse chefo, ha e bonts'e thepa ea mutagenic, carcinogenic kapa allergenic.

Litaelo tse khethehileng

Ho / ho kenyelletsa tharollo ha hoa lumelloa!

Sebakeng sa lefu la tsoekere mellitus, ho hlokahala ho laola boemo ba tsoekere ea mali nakong ea phekolo (ho eketseha ha hypoglycemia ho ka etsahala).

Desoxinate: sesupo sa tšebeliso ea prophylactic ke ho ba teng ha leukopenia (ka tlase ho likete tse 3.5 / μl) le / kapa thrombocytopenia (150,000 / μl) pele ho qala ha phekolo e itseng, leukopenia le / kapa thrombocytopenia, e qalileng nakong ea potoloho e fetileng ea chemo- kapa chemoradiotherapy (2,5 le Ba likete tse lekholo / μl, ka ho latellana).

Tabeng ea leukopenia le / kapa thrombocytopenia e etsahetseng nakong ea chemo / chemoradiotherapy kapa pheletso ea eona, matšoao a ts'ebeliso ea lithethefatsi ke phokotseho ea litaba tsa leukocytes maling a potoloho ho isa ho likete tse 2 / μl, liplatelete - 100 likete / μl kapa ka tlase.

Mofumahali

Ha e sebelisoa ka mokhoa o hlophisitsoeng, deoxinate e kenella mme e ajoa ka litho le lisele ka ho ba le seabo tseleng ea endolymphatic. Mokhahlelong oa ts'ebeliso e matla ea lithethefatsi maling, ho abuoa hape pakeng tsa plasma le lisele tsa mali, hammoho le metabolism le excretion.

Desoxinate e tšeloa 'mele' meleng. Li-metabolites tsa ho qetela ke xanthine, hypoxanthine, beta-alanine, acetic, propionic le uric acid, tse tsoang mokhoeng oa ka mpeng.

E ntšitsoe 'meleng (ka sebopeho sa metabolites) ke liphio ho latela bokhoni ba ts'epahalo ea biexponential' me, ka karolo e 'ngoe, ka pampitšana ea gastrointestinal.

Lipontšo Deoxinate

• liso tsa pele tsa radiation ea morao, le mocheso o chesang oa letlalo la boemo ba boima ba II-III,
• mahlaseli a kotsi a radiary pharyngeal syndrome,
• trophic ulcers
• tlolo ea botshepehi ba membrane ea mucous ea molomo, nko, botšehali, rectum,
• Litlhoko tsa ho hlaba kahare ho molomo le letlalong.
• mathata a amanang le kalafo ea cytostatic (stomatitis, pharyngoesophagitis, gingivitis, uvulitis, enterocolitis, vulvovaginitis, paraproctitis),
• ho hlophisoa ha lisele bakeng sa auto- kapa allotransplantation le nakong ea ts'ebetso ea pala.

Melemo ea litekanyetso

Sethethefatsi se laetsoe bana ho tloha ka letsatsi la pele la bophelo le batho ba baholo.

Bakeng sa kalafo ea maqeba a letlalo, kenya litlolo ka tharollo ea Deoxinate, e nkeloe makhetlo a 3-4 ka letsatsi.

Ha ho ruruha mucosa ea molomo, li-rinses li etsoa ka tharollo ea Deoxinate (makhetlo a 4 ka letsatsi, 5-15 ml, e lateloe ke ho koenya).

Ka hara botshehadi, Deoxinate e tsamaisoa ka swab, ho rectum ka enema (20-50 ml).

Nako ea karolelano ea kalafo ke ho nyamela ho sa feleng hoa matšoao a ho ruruha le ho hlohlona matlalong a letlalo le mucous (matsatsi a 4-10).

Pharadodynamics

Deoxinate e bontša phello ea immunomodulatory maemong a cellular le a tlotlollang. Sesebelisoa se thusa ho kenya ts'oaetso ea antifungal, antiviral le antimicrobial. E na le ts'ebetso ea radioprotective, e tsosa tsoelo-peleng - e eketsa pholiso ea maqeba le liso tsa maqeba a ho ruruha ha letlalo le li-membrane tsa mucous, e hlohlelletsa ho etsoa ha granulations le epithelium. Ha o sebelisa tharollo bakeng sa ts'ebeliso ea lehae le kantle ka mokhoa oa lits'ebetso, liaparo le li-rinses, phello ea analgesic e boetse e bonoa, botebo ba karabelo ea ts'oaetso bo fokotsehile. Ntho e sebetsang e laola hematopoiesis - e thusa ho etsa hore palo ea liukocytes, phagocytes, granulocytes, liplatelete, lymphocyte. Deoxinate e lebisa keketseho ea ts'ebetso ea "autograft" kalafong ea ho chesoa ka holimo feela, hammoho le lisebelisoa tsa bongaka tsa ho buoa ka polasetiki tsa bofokoli le bofokoli ba sebaka se seholo sa maxillofacial.

Ho latela data ea liteko, Deoxinate e bontša phello ea kalafo khahlano le bokuli ba mahlaseli a mahlaseli a II - III a ho teba ha maemo a hypo- le aplastic a tsamaiso ea mali a bakiloeng ke radiation kapa polychemotherapy. Kamora taolo e le 'ngoe ea i / m ea lithethefatsi, phello e potlakisang ho phahamisa e bonoa ho bakuli ba nang le mofetše ka leukopenia ea III le li-degree tsa IV tse sokelang bophelo tse bakoang ke ts'ebeliso ea polychemotherapy kapa polychemotherapy e kopaneng. Pele ho tsohle, maemong ana, keketseho ea boemo maling a pherite ea makhetlo a 5-7 palo e felletseng ea granulocytes e tlalehiloe. Ka nako e ts'oanang, ka lebaka la ts'ebetso ea lithethefatsi, keketseho ea palo e felletseng ea li-lymphocyte le ho tloaeleha ha boemo ba mahloriso a liplatelete maling a pherekano li bonoa ka thrombocytopenia ea degree ea I-IV ea genesis e tšoanang.

Deoxinate ha e ame kholo ea tumor le phello ea kalafo ea cytostatics kapa chemoradiotherapy, ha e lebise litlamorao tse potlakileng kapa tse liehang, ha e na thepa ea mutagenic, carcinogenic kapa allergic.

Ka lebaka la ente e le 'ngoe ea IM ea moemeli ea emisang mali nakong ea lihora tse 24 tse qalang kamora ho pepesehela mahlaseli a kotsi a ionizing, thupelo ea bongaka ea lefu la radiation e ntlafalitsoe litekong, ho qaleng le tekanyo ea ho khutlisetsa lisele tsa stem mokokotlong oa masapo, hammoho le lymphoid, myeloid le platelet hematopoiesis li potlakisitsoe.

Ka lebaka la ts'ebetso ea moriana, monyetla oa litlamorao tse ntle tsa bokuli ba radiation oa eketseha. Tšusumetso e ntle ea kalafo ea Deoxynate e bonoa ho acute pharyngeal syndrome, ho chesoa ha mocheso, liso tsa radiation tsa mantlha le tsa morao, le mathata a amanang le kalafo ea cytostatic.

Tharollo bakeng sa tsamaiso ea i / m le s / c

• myelodepression e matla (leuko- le thrombocytopenia) ho bakuli ba nang le mofetše, ka lebaka la cytostatics (mono- kapa polychemotherapy) kapa chemoradiotherapy (kalafo) e kopaneng.
• leuko- le thrombocytopenia e fumanoeng mokelikeng o fetileng oa chemo- kapa chemoradiotherapy, boteng ba thrombocytopenic (ka tlase ho 150x10 9 / l) leukopenic (ka tlase ho 3,5x10 9 / l) nalane pele ho qala kalafo e itseng - bakeng sa thibelo, pele ho potoloho ea chemotherapy. kapa irradiation ea k'hemistri, haholo-holo e phetoang, nakong ea eona kapa ka mor'a eona, leukopenia le / kapa thrombocytopenia e ileng ea hlaha nakong ea chemotherapy (chemoradiotherapy) kapa kamora ho phethoa, letšoao la tšebeliso. Ho lokisa lithethefatsi ke ho fokotseha hoa boemo ba leukocytes maling a peripheral ho 2x10 9 / l, liplatelete 100x10 9 / l kapa ka tlase.

Ho latela data ea liteko, Deoxinate e boetse e bontšoa ho bakuli ba pepesetsoeng mahlaseli a kotsi a methapo e lebisang nts'etsopele ea bokuli ba radiation ea maemo a boima ba II - III.

Tharollo bakeng sa ts'ebeliso ea lehae le kantle

• mahlaseli a kotsi a radiary pharyngeal syndrome,
• liso tsa mantlha, tsa morao-rao tsa mahlaseli a chesang le ho chesoa ke mocheso letlalo la II - III tekanyo ea boima,
• trophic ulcers
• Litlhoko tsa ho hlaba kahare ho molomo le letlalong.
• tlolo ea botshepehi ba membrane ea mucous ea mucal, molomo, rectum, vagina,
• mathata a amanang le kalafo ea cytostatic: gingivitis, pharyngoesophagitis, uvulitis, stomatitis, enterocolitis, paraproctitis, vulvovaginitis,
• nako ea ts'ebetso ea temo, ho hlophisoa ha lisele bakeng sa auto- kapa allotransplantation.

Contraindication

Ntho e khahlanong le tšebeliso ea Deoxinate ke ho se mamellane ha likarolo tsohle tsa eona.

Ntle le moo, tharollo ea tšebeliso ea lehae le kantle ha e khothaletsoe ho basali baimana le ba anyesa.

Ka hloko le feela kamora ho buisana le ngaka le ho hlahloba ka hloko melemo ea kalafo e lebelletsoeng ho mme le tšitiso e ka bang teng bophelong ba masea, tharollo ea i / m le s / c tsamaiso e ka sebelisoa nakong ea kemolo. Nakong ea ho anyesa, mofuta ona oa moriana o ka sebelisoa ka mokhoa o thata joalokaha o laetsoe ke ngaka.

Litlamorao

Tsamaiso ea / / m le s / c ea Deoxinate ha e lebise ho mathata. Maemong a mang, lihora tse 4 - 24 kamora ho ente, hyperthermia ea nako e khuts'oane (e seng ho feta lihora tse 2-5) e ka bonoa ho tloha ho boleng bo tlase ho isa ho 38,5 ° C, hangata ntle le ho mpefatsa boemo ba mokuli (ho tlola, joalo-joalo) mme e sa hloke khalemelo. Tabeng ea tsamaiso e qobelloang ea tharollo, ho na le bohloko bo bokhutšoanyane sebakeng sa ente, bo sa hlokeng kalafo ea lithethefatsi.

Ha e sebelisoa sebakeng sa hau, moemeli oa immunomodulatory ha a bake tsoalo ea liketsahalo tse bohloko.

Haeba maikutlo leha e le afe a kaholimo a mpefalitsoe, kapa mathata a mang a hlahelang khahlano le tšebeliso ea Deoxinate, o lokela ho bona ngaka ea hau.

Bokhachane le pelehi

Tharollo ea tšebeliso ea lehae le kantle ha e khothaletsoe ho basali baimana le ba anyesa.

Tharollo bakeng sa tsamaiso ea i / m le s / c nakong ea kemaro e ka sebelisoa kamora ho buisana le ngaka le ho hlahloba ka hloko melemo ea kalafo e lebelletsoeng ho mme le likotsi tse ka bang teng bophelong ba masea. Nakong ea kanyeso, mofuta ona oa Desoxinate o ka sebelisoa ka mokhoa o thata joalokaha o laetsoe ke ngaka.

Ho sebelisana le lithethefatsi

Ha ke / m le s / ho kenyelletsa, deoxinate e hlahisa phello ea li-cytostatics le lithibela-mafu tsa antitumor - anthracyclines.

Ha e sebelisoa ka holimo, sethethefatsi se ke ke sa kopana le tharollo ea hydrogen peroxide le litlolo tse thehiloeng holim'a mafura.

Li-Analogue tsa Deoxinate ke Derinat, Panagen, Sodium deoxyribonucleate, Ridostin, jj.

Litlhahlobo mabapi le Deoxinate

Litlhahlobo tsa deoxyninate liwebsaeteng tsa bongaka ha li nke letho. Bakuli ba bangata ba ne ba khotsofetse ke kalafo ea lithethefatsi, haholo-holo ka mokhoa oa tharollo bakeng sa tšebeliso ea lehae le kantle, 'me ba lumela hore ka nepo e na le phello e boletsoeng. Ho hlokomeloa hore moriana o iponahalitse kalafong ea stomatitis, furunculosis e khutliselitsoeng morao, ulophic ulcers, maqeba a marang-rang a marang-rang, li-adtions tsa mokokotlo, endometritis e sa foleng. Tharollo ea Deoxinate ka ampoules (bakeng sa tsamaiso ea i / m le s / c), ho latela tlhahlobo ea bakuli, e bontšitse litholoana tse ntle kalafong ea leukopenia. Litlhahlobong tsa litsebi, moriana o bitsoa mokhoa o sebetsang oa kalafo ea kalafo ea radiation.

Leha ho le joalo, ho boetse ho na le litletlebo tsa bakuli tseo ho tsona ba supang phello e fokolang ea kliniki ea moemeli ea emisang lihlahisoa tsa mmele, hammoho le nts'etsopele ea litla-morao le bohloko sebakeng sa ente ea eona ea methapo. Hangata ho na le khaello ea lithethefatsi libakeng tsa meriana.

Theko ea deoxinate libakeng tsa meriana

Theko ea Desoxinate ha e tsejoe ka lebaka la hore lithethefatsi ha li fumanehe hona joale marang-rang a litlama.

Theko ea analogue ea lithethefatsi, Derinat, tharollo ea tšebeliso ea lehae le kantle ho 0.25%, e kanna ea ba li-ruble tse 208-327. ka botlolo ea 10 ml. Derinat ka mokhoa oa tharollo bakeng sa tsamaiso ea methapo ea methapo e ka bang 15 mg / ml e ka rekoa li-ruble tsa 1819-2187. ka pakete e 5 ea li-5 ml.