Mokhoa oa ho sebelisa lithethefatsi Gluconorm Plus?

- lefu la tsoekere ketoacidosis, lefu la tsoekere, lefu la tsoekere,

- Ho lemala hampe renal,

- maemo a hlobaetsang a ka lebisang phetohong ea ts'ebetso ea liphio (ho omella, ts'oaetso e matla, ho tsitsipana),

- mafu a hlobaetsang kapa a sa foleng a tsamaeang le "hypoxia" ea methapo (pelo kapa ho se khone ho phefumoloha, infarction ea myocardial ea morao-rao, tšabo),

- mafu a tšoaetsanoang, ts'ebetso e kholo ea ts'ebetso ea ho buoa, likotsi, ho chesa haholo le maemo a mang a hlokang kalafo ea insulin,

- Joala bo sa foleng, ho tahoa ho hoholo,

- lactic acidosis (ho kenyeletsoa le nalane),

- Sebelisa bonyane lihora tse 48 pele le ka hare ho lihora tse 48 kamora ho etsa lithuto tsa radioisotope kapa X-ray ka ho hlahisoa ha iodine e nang le phapang e mahareng.

- ho latela mokhoa oa ho ja lijo tse nang le khalori e tlase (ka tlase ho likhalori tse ka tlase ho 1000 / letsatsi),

- nako ea ho anyesa,

- Hypersensitivity ho metformin, glibenclamide kapa tse ling tse tsoang sulfonylurea, hammoho le lintho tse thusang.

Mokhoa oa ho sebelisa: litekanyetso le kalafo

Ka hare, ha o ntse o ja.

Hangata tekanyetso ea pele ke 1 tab. (400 mg / 2.5 mg) / letsatsi. Ka mor'a libeke tse ling le tse ling tse peli kamora ho qala kalafo, tekanyetso ea moriana e lokisoa ho latela boemo ba tsoekere ea mali. Ha u khutlisetsa kalafo ea motsoako e fetileng le metformin le glybeklamide, ho boleloa matlapa a 1-2. Gluconorm ho latela tekanyetso e fetileng ea karolo ka 'ngoe.

Sekhahla se phahameng sa letsatsi le letsatsi ke matlapa a 5.

Ketso ea pharmacological

Glibenclamide e phahamisa secretion ea insulin ka ho theola monyako oa khatello ea kelello ea beta-cell pancreatic, e eketsa kutloisiso ea insulin le tekanyo ea ho tlama ha eona ho lisele tse tobileng.

Metformin e fokotsa tsoekere ea serum ka ho eketsa kutloisiso ea lithane tsa pherekano ho insulin le ho ntlafatsa ho ts'oaroa ha tsoekere.

Litlamorao

Karolong ea metabolism ea carbohydrate: hypoglycemia e ka etsahala.

Ho tsoa mokokotlong oa mala le sebete: ka seoelo - ho nyekeloa, ho hlatsa, mpeng, ho felloa ke takatso ea lijo, tatso ea "metallic" molomong, maemong a mang - cholestatic jaundice, ts'ebetso e eketsehileng ea li-enzyme tsa sebete, hepatitis.

Ho tsoa ho sistimi ea hemopoietic: ka seoelo - leukopenia, thrombocytopenia, erythrocytopenia, ka seoelo - agranulocytosis, hemolytic kapa megaloblastic anemia, pancytopenia.

Boitšoaro bo ho kula le ba immunopathological: ka seoelo - urticaria, erythema, ho hlohlona ha letlalo, feberu, arthralgia, proteinuria.

Boitšoaro ba methapo ea methapo: ka seoelo - photosensitivity.

Ho tloha ka lehlakoreng la metabolism: lactic acidosis.

Litaelo tse khethehileng

Lits'oaetso tse kholo tsa ho buoa le ho lemala, ho chesa haholo, mafu a tšoaetsanoang a nang le febrile syndrome ho ka hloka hore ho tlohele lithethefatsi le ho khethoa ha kalafo ea insulin.

Hoa hlokahala hore kamehla u lekole boemo ba tsoekere maling maling ka mpeng e se nang letho le ka mor'a ho ja.

Bakuli ba lokela ho lemosoa ka kotsi e eketsehang ea hypoglycemia maemong a ethanol, NSAIDs, le tlala.

Tšebelisano

Ethanol e eketsa menyetla ea lactic acidosis.

Barbiturates, corticosteroids, adrenostimulants (epinephrine, clonidine), lithethefatsi antiepileptic (phenytoin), butle-butle calcium Channel blockers, carbonic anhydrase inhibitors (acetazolamide), thiazide diuretics, chlortalidone, furosemide, diazanazide , morphine, ritodrine, salbutamol, terbutaline, tsoekere, rifampicin, lihomone tsa qoqotho tse nang le iodine, letsoai la lithium, litekanyetso tse phahameng - nicotinic acid, chlorpromazine, lithibela-pelehi tsa molomo le estrogens.

Li-inhibitors tsa ACE (Captopril, enalapril), histamine H2 receptor blockers (cimetidine), li-antifungal agents (miconazole, fluconazole), NSAIDs (phenylbutazone, azapropazone, oxyphenbutazone), fibrate, lithibela-mafu (clobate) , salicitates, coumarin anticoagulants, anabolic steroids, beta-blockers, li-inhibitors tsa MAO, sulfonamides ea nako e telele, cyclophosphamide, chloramphenicol, phenfluramine, fluoxetine, guanethidine, pentoxifylline, tetracycline, theophylline, tubular secretion blockers, reserpine, bromocriptine, disopyramide, pyridoxine, lithethefatsi tse ling tsa hypoglycemic (acarbose, biguanides, insulin), allopurinol.

Lipotso, likarabo, litlhahlobo mabapi le lithethefatsi Gluconorm Plus

Tlhahisoleseling e fanoeng e reretsoe litsebi tsa bongaka le tsa meriana. Tlhahisoleseling e nepahetseng ka ho fetelletseng ka lithethefatsi e fumaneha litaelong tse tlamelletsoeng ke moqapi. Ha ho na tlhahisoleseling e thathamisitsoeng leqepheng lena kapa leha e le efe ea sebaka sa rona sa marang-rang e ka sebeletsang e le sebaka sa boipiletso ba motho ho setsebi.

Lokolla liforomo le sebopeho

Setlhare se fumaneha feela ka foromo ea letlapa. E na le metsoako e sebetsang: glibenclamide le metformin hydrochloride. Litekanyetso tsa letlapa le le leng, 1 ka ho latellana: 2,5 le 5 mg, 500 mg. Ntle le motsoako ona oa lintho, sebopeho se kenyeletsa likarolo tse thusang bakeng sa mofuta ona oa tokollo:

• phospholle cellulose,
• Hyprolose
• sodium hammart
• magnesium stearate.

Matlapa a koahetsoe ka koae e khethehileng e fokotsang sekhahla sa ho lokolloa ha lintho tse sebetsang. Ka lebaka lena, boemo ba phello e mabifi likarolong tsa mucous tsa mpa li ea fokotseha. O ka reka sehlahisoa ka har'a lipakete tse nang le matlapa a 30.

Setlhare se fumaneha feela ka foromo ea letlapa. E na le metsoako e sebetsang: glibenclamide le metformin hydrochloride.

Mofumahali

Metformin e kenella ka potlako. Tekanyo ea ho ts'oaroa ha eona serum ea mali e nyoloha ho fihlela boleng ba moeli kamora lihora tse peli. Bothata ba ntho ke ketso e kgutshwane. Kamora lihora tse 6, ho fokotseha hoa khatello ea plasma ea metformin ho qala, ka lebaka la ho felisoa ha ts'ebetso ea lijo. Bophelo ba halofo ea ntho le bona bo fokotsehile. Nako ea eona e fapana ho tloha lihora tse 1.5 ho isa ho tse 5.

Ntle le moo, metformin ha e amane le liprotheine tsa plasma. Ntho ena e na le matla a ho bokella liseleng tsa liphio, sebete, litšoelesa tsa salivary. Ts'ebetso ea renal e senyehileng ke eona ntho e ka sehloohong e tlatsetsang ho bokelleng ha metformin 'meleng, e lebisang keketseho ea karolo ena le keketseho ea katleho ea eona.

Ts'ebetso ea renal e senyehileng ke eona ntho e ka sehloohong e tlatsetsang ho bokelleng ha metformin 'meleng, e lebisang keketseho ea eona.

Glibenclamide e nka nako e telele - bakeng sa lihora tse 8-12. Tlhōrō ea katleho e etsahala lihoreng tse 1-2. Ntho ena e tlameletsoe ka botlalo ho liprotheine tsa mali. Ts'ebetso ea phetoho ea glibenclamide e etsahala sebeteng, moo ho thehang metsoako e 'meli e sa bontsheng ts'ebetso ea hypoglycemic.

Matšoao a ho sebelisoa

Moriana o lumelloa ho sebelisoa kalafo ea bakuli ba nang le lefu la tsoekere la mofuta oa 2 maemong a mang:

• ho hloka litholoana ka kalafo e laetsoeng pele ho botenya, haeba ho na le lithethefatsi: Metformin kapa Glibenclamide li sebelisitsoe,
• ho etsa kalafo ea phetisetso, ha feela boemo ba tsoekere maling bo tsitsitse ebile bo laoloa hantle.

Fomu ea tokollo

Gluconorm e etsoa ka mokhoa oa matlapa a chitja a moriti o mosoeu ka membrane e koahetsoeng. Likotoana tse 10 le tse 20 ka paketeng e nang le lithutsoana, lithutsoana tse peli kapa tse 'ne ka har'a pakete ea likarete.

Theko ea gluconorm e tsoa ho li-ruble tse 220 ho isa ho tse 390, ho ipapisitsoe le palo ea matlapa a pakaneng ea karete.

Moriana o na le lintho tse peli tsa sehlooho - glibenclamide (2,5 mg) le metformin hydrochloride (0,4 g).

Mefuta e meng: cellcosestalline cellulose, starch ea poone, colloidal silicon dioxide, talc e hloekisitsoeng, diethyl phthalate, gelatin, cellulose acetate phthalate, sodium carboxymethyl starch, croscamellose sodium.

Litaelo tsa ho sebelisoa

Matlapa a Gluconorm a nkuoa ka molomo ha a ntse a ja. Tekanyetso e khethoa ka bonngoe, e ipapisitse le boemo ba tsoekere maling maling a mokuli. Tekanyetso e tloaelehileng qalong ea kalafo ke pilisi e le 'ngoe ka letsatsi. Kamora libeke tse peli, ho hlokahala hore u fetole tekanyetso ea moriana ho latela boleng ba liteko tsa mali.

Litaelo tsa ts'ebeliso ea Gluconorm li bonts'a hore ka kalafo e emisang e tlameha ho nka matlapa a 1-2, ho nahanisisa ka lintlha tse fetileng tsa likarolo tse kholo. Tekanyo e phahameng ka ho fetisisa ka letsatsi e fihla ho matlapa a 5.

Matlapa a Hypoglycemic ke ngaka. Li tlameha ho bolokoa ka mocheso ho fihlela ho li-degrees tsa 25 ponong ea letsatsi le letsatsi ea ngoana. Botshelo ba bophelo ba sehlahisoa ke likhoeli tse 36 ho tloha ka letsatsi la tlhahiso.

Likarolo tsa ts'ebeliso

Hoa hlokahala ho hlakola kalafo le lithethefatsi bakeng sa mafu a tšoaetsanoang a nang le feberu, ka likotsi tse ngata le ho kenella ha opereishene. Kotsi ea ho fokotsa khatello ea tsoekere nakong ea tlala, ts'ebeliso ea li-NSAIDs, ethanol ea eketseha. Phetoho ea litekanyetso li etsoa ha ho fetoloa phepelo, mokhathala o matla oa 'mele le mmele.

Ntlafatso ea lefu la tsoekere - e-nooa feela letsatsi le leng le le leng.

Litaelo Gluconorm e hlalosa hore ha ho khothalletsoe ho noa joala nakong ea kalafo. Lipilisi li ka ama lebelo la karabelo ea psychomotor le ho fokotsa khatello ea maikutlo. Ka hona, o tlameha ho ba hlokolosi ha o khanna makoloi le likoloi tse kotsi.

Ha hoa lumelloa ho sebelisa lipilisi bongoaneng, nakong ea kemolo, nakong ea kanyeso, hobane likarolo tsa mantlha li kena lebeseng la mme. Moriana ona o kopantsoe le batho ba nang le methapo ea liphio le sebete. Ts'ebeliso ea matlapa a maqheku ha e khothaletsoe hammoho le ho ikoetlisa ka matla.

Bongata

Ho iphekola le ho tšela litekanyetso tse lumelloang ho lebisa ho lithethefatsing tse fetang tekano. Boemo bona bo lebisa ponahalong ea lactic acidosis ka lebaka la metformin, e leng karolo ea meriana. Mokuli o hlokomela ponahalo ea ho nyekeloa ke pelo, ho hlatsa, bofokoli, mesifa ea mesifa. Ka matšoao a pele a overdose, kalafo e felisitsoe. Ka lactic acidosis, kalafo e etsoa setsing sa bongaka. Phekolo e sebetsang ka ho fetisisa ke hemodialysis.

Re fana ka theolelo ho babali ba sebaka sa rona sa marang-rang!

Motsoako ona o na le glibenclamide, khatello e phahameng ea eona e bakang kholo ea hypoglycemia. Matšoao a mantlha a boemo bona:

• hlooho e bohloko
• ho tsekela
• takatso e matla ea lijo
• bofokoli bo akaretsang
• pallor of the epidermis,
• boikutlo ba ho tšoha
• mathata a methapo,
• arrhythmia,
• ho otsela
• mathata a khokahano
• toro e mpe
• paresthesia ea mucosa ea molomo.

Ka ho mpefala ha hypoglycemia, ho mpefala ha boemo ba mokuli, tahlehelo ea taolo le ho ts'oaroa hoa hlokomeloa. Ka lefu le bobebe le ho leka-lekana la lefu lena, tsoekere e khethoa. Maemong a hlobaetsang le ho feta, ha motho a lahleheloa ke kelello, ho sebelisoa tharollo ea glucose ea 40% kapa glucagon. Ho qoba ketsahalo e latelang ea hypoglycemia, mokuli o lokela ho ja lijo tse ngata tse nang le lik'habohaedreite kamora ho tseba hantle.

Moriana ona o ka nkeloa sebaka ke lithethefatsi tse kang Bagomet Plus le Glukovans. Lihlahisoa tsena li na le sebopeho se ts'oanang le Gluconorm. Matlapa a kang Glucofage le Glybomet ke litšoantšo tsa Gluconorm tse nang le metformin. Ho thibetsoe ka thata ho sebelisa lithethefatsi tse ling ntle le taelo ea ngaka ho qoba mathata le ho mpefatsa boemo ba mokuli.

Matlapa a thusa bakuli ba bang, ha a mang a baka litla-morao. Ka tlase ke litlhahlobo tse ling tsa lefu la tsoekere Gluconorm.

Ke fumanoe ke lefu la tsoekere lilemo tse 7 tse fetileng. Ngaka e laetse Gluconorm e le pheko e ncha. Ke nwa Letlapa le le leng ka letsatsi, ke hlatsoitsoe ka metsi. Ke ikutloa ke le betere. Kalafo ea ka e kenyelletsa ho sebelisa meriana, ho ja. Ho fihlela joale, ha ho lipontšo tse mpe tse hlokometsoeng.

Ka lefu la tsoekere, ke ne ke laetsoe hore ke noe Gluconorm letsatsi le leng le le leng hoseng le mantsiboea. Glucose e maling e khutletse ho tloaelehileng, empa hlooho e bohloko le mathata a amanang le tšilo ea lijo a ile a hlaha. Qetellong, ke na le litlolo tsa molao tsa mofuta ona. Ke ile ka tlameha ho fetola moriana.

Lefu la tsoekere le lula le baka mathata a bolaeang. Tsoekere e ngata haholo e kotsi haholo.

Aronova S.M. e fane ka litlhaloso mabapi le kalafo ea lefu la tsoekere. Bala ka botlalo

Sehlopha sa mahlale

Sebopeho sa Gluconorm se kenyelletsa likarolo tse peli, tseo hammoho li fanang ka phello ea hypoglycemic.

Metformin ke ea sehlopha sa Biguanides, e eketsang ho hanyetsa ha lisele ho insulin, e tlatsetsang ts'ebetsong ea tsoekere e potlakileng. Ntho ena e ama lits'ebetso tsa metabolic ka har'a sebete, e boloka botsitso tlhahiso ea k'holeseterole le triglycerol. Ho kenngoa ha lik'habohaedreite ho tsoa ho tšilo ea lijo ho fokotsehile.

Glibenclamide ke mofuta oa sulfonylurea. Ka thuso ea eona, secretion ea insulin e etsoa, ​​e fumanoang ka ho pepesetsoa lisele tsa pancreatic. E fana ka maikutlo a eketsehileng a lisele tsa 'mele ho insulin, e thibelang lipolysis ea lithane tsa adipose.

Tekanyetso le tsamaiso

Mokhoa o nepahetseng ka ho fetisisa oa lithethefatsi o khethoa ke ngaka, ho latela matšoao a tsoekere ea mali. Phekolo e qala ka litekanyetso tse fokolang tsa moriana, e leng halofo ea letlapa hang ka letsatsi.

Bakeng sa ho qoba nts'etsopele ea hypoglycemia, ho khothalletsoa ho nka letlhare le le leng la moriana 1 ka letsatsi le lijo. Sena se etsoa hantle hoseng haholo, ka lebaka la ho fokotseha ha lits'ebetso tsa metabolic kamora lijo tsa motšehare.

Ha ho se na ts'ebetso, litekanyetso li eketseha butle-butle. Tekanyo e kholo ea letsatsi le letsatsi ha ea lokela ho feta matlapa a 5-6. Haeba ho hlokahala ho sebelisa tekanyetso e phahametseng e khothalletsoang, mokuli o lokela ho lula a beiloe leihlo ke litsebi haholo.

Gluconorm hape

Keketseho e eketsehileng ea Glibenclamide e u lumella hore u sebelise letlapa le le leng feela ka letsatsi ho fumana phello e tsitsitseng ea hypoglycemic. Ke mofuta oa kalafo e loketseng maemong a itseng, ngaka e tla u joetsa.

Ke litafole tsa gluconorm hammoho le 'ona li shebahala joang

Ka tloaelo, kalafo e qala ka Gluconorm e tloaelehileng, ka ho se sebetse hantle ha ba fetohela foromo e ntlafalitsoeng e nang le litaba tse phahameng tsa Glibenclamide.

Ho sebelisana le lithethefatsi

Ts'ebeliso e tšoanang ea lithethefatsi Gluconorm plus le Miconazole, le lithethefatsi tse ling tsa antimycotic, tseo ha li sebelisana, li qholotsang nts'etsopele ea lefu la tsoekere, leha e le ho bolaea, li thibetsoe ka thata.

Se ke oa nka gluconorm ka joala

U ke ke ua sebelisa moemeli oa hypoglycemic hammoho le joala, bo bakang ho fokotseha ha methapo ea mali le khatello ea pelo.

Ka tlhokomeliso e fetelletseng, sethethefatsi sena se kopantsoe le glucocorticosteroids le lithethefatsi, tse kenyeletsang iodine.

Likarolo tsa tšebeliso

Gluconorm ha e khothalletsoe ho bakuli kamora lilemo tse 65, ka lebaka la likotsi tse kholo tsa ho ba le maikutlo a mabe, ho kenyelletsa le ho holisa lefu la tsoekere. Kamora lilemo tse 45, kalafo e qala ka tekanyetso e fokolang, mme haeba ho hlokahala, keketseho ea bona e hloka ho lekoloa khafetsa boemo ba mokuli.

Nakong ea kemolo, tšebeliso ea moriana ona e thibetsoe ka tieo, hobane likarolo tse sebetsang li kenya letsoho tlolong ea kholo ea botlalo ba lesea.Sena le sona se eketsa likotsi tsa li-pathologies tsa tsoalo, hammoho le ho senyeheloa ke mpa maemong a pele.

Lithethefatsi tse latelang li tšoana ka sebopeho le phello ea kalafo:

Khetho ea sesebelisoa se le seng kapa se seng se ka fokotsang tsoekere ea mali ho latela tekanyo ea tsoelo-pele ea lefu la tsoekere le mafu a amanang le ona. Ke ngaka feela e nang le tokelo ea ho buella moriana, o khetha litekanyetso tse nepahetseng ho fetisisa boemong bo itseng. Ho ikoetlisa ho kotsi bakeng sa ho holofala ha lefu la tsoekere le lintho tse ling tse mpe tse ka re behang bophelong.