Ciprolet® (250 mg) Ciprofloxacin
- matlapa a koahetsoeng ka filimi: biconvex e pota-potileng, e nang le boreleli, leqhetsoana le bokhutšoanyane ba letlapa li batla li le bosoeu kapa bosoeu (likotoana tse 10 e ngoe le e ngoe ka blister, ka lebokoseng la mekotla e le 'ngoe ea lilakane tse peli kapa tse peli),
- Tharollo ea infusion: Mokelikeli o se nang 'mala kapa o bobebe ba' mala o mosehla (100 ml e ngoe le e ngoe ka botlolong ea polasetiki, botlolo e le 'ngoe e kentsoeng ka karete ea karete).
- marotholi a leihlo: metsi a hlakileng a 'mala o mosehla kapa o se nang mebala (5 ml e' ngoe le e ngoe ka botlolong ea polasetiki e lahla, botlolo e le 'ngoe ka mokotleng oa karete).
Letlapa le le leng le na le:
- ntho e sebetsang: ciprofloxacin hydrochloride - 291.106 mg kapa 582.211 mg, e lekanang le litaba tsa 250 mg kapa 500 mg tsa ciprofloxacin (ka ho latellana),
- likarolo tse thusang: croscarmellose sodium, starch ea poone, colloidal silicon dioxide, cellcose ea microcrystalline, magnesium stearate, talc,
- Sebopeho sa khetla: sorbic acid, hypromellose (6 cps), macrogol 6000, polysorbate 80, titanium dioxide, dimethicone, talc.
1 ml ea tharollo e na le:
- ntho e sebetsang: ciprofloxacin - 2 mg,
- likarolo tse thusang: hydrochloric acid, chloride ea sodium, lactic acid, edetate ea sodium, sodium hydroxide, citric acid monohydrate, metsi bakeng sa ente.
1 ml lerotholi
- ntho e sebetsang: ciprofloxacin hydrochloride - 3,49 mg, e lekanang le litaba tsa 3 mg ea ciprofloxacin,
- likarolo tse thusang: edetate ea disodium, 50% tharollo ea benzalkonium chloride, hydrochloric acid, chloride ea sodium, metsi a ente.
Matlapa a koahetsoeng ka filimi le tharollo ea infusion
Ts'ebeliso ea Ciprolet ka mokhoa oa litafole le tharollo e bontšoa bakeng sa kalafo ea mafu a tšoaetsanoang le a tšoaetsanoang a bakoang ke likokoana-hloko tse utluoang ke ciprofloxacin.
- tšoaetso ea meno, molomo, mehlahare, phepelo ea ka mpeng,
- tšoaetso ea tsebe, nko le 'metso,
- tšoaetso ea phepelo ea phefumoloho
- tšoaetso ea gallbladder le biliary pampitsana,
- ts'oaetso ea liphio le tsamaiso ea moroto
- ts'oaetso ea musculoskeletal,
- tšoaetso ea mucous membrane, letlalo le lisele tse bonolo,
- ts'oaetso ea pelehi
- liphatsa tsa lefutso (prostatitis, gonorrhea, adnexitis),
- sepsis
- peritonitis.
Ntle le moo, matlapa le tharollo li sebelisoa e le karolo ea kalafo e rarahaneng e nang le li-immunosuppressants ho thibelo le kalafo ea tšoaetso ho bakuli ba nang le boits'ireletso ba mmele.
Leihlo la theoha
Ts'ebeliso ea marotholi e bonts'oa molemong oa kalafo ea tšoaetso ea methapo ea mahlo le mahlaseli a bakoang ke libaktheria tse amehang lithethefatsi:
- subacute le a hlobaetsang le conjunctivitis,
- blepharoconjunctivitis, blepharitis,
- liso tsa corneal tsa etiology
- keratoconjunctivitis, keratitis ea baktheria,
- mofuta o sa foleng oa meibomite le dacryocystitis,
- mathata a tšoaetsanoang ka mor'a ho buuoa,
- mathata a tšoaetsanoang ka mor'a ho tsoa likotsi tsa mahlo kapa 'mele o tsoang ka ntle ho ona (o kenyeletsa thibelo ea' ona).
Ntle le moo, marotholi a sebelisoa ts'ebetsong ea opereishene ea mahlo bakeng sa thibelo ea tšebeliso.
Contraindication
- nako ea kemaro le kanyeso,
- mamello ea motho ka mong ho itokisetsa sehlopha sa fluoroquinolone,
- hypersensitivity ho likarolo tsa moriana.
Ka hlokolosi, Cyprolet e lokela ho fuoa kalafo ea methapo ea methapo, kotsi ea methapo ea methapo, le methapo ea kutlo.
Ntle le moo, arola likhakanyo tsa mofuta ka mong oa litekanyetso.
Tharollo ea infusion
Tharollo e reretsoe tsamaiso ea methapo ea methapo (iv).
Tharollo ea infusion e ka tsoakoa le tharollo ea sodium chloride ea 0,9%, tharollo ea 10% ea tharollo, tharollo ea 5% le 10% dextrose, tharollo ea Ringer, tharollo e nang le tharollo ea 5% dextrose le 0,2525% kapa 0,45% sodium chloride.
Ha u fana ka lethal dose, matšoao a bongaka, mofuta oa ts'oaetso, boemo, lilemo le boima ba mokuli, li-pathologies tse amanang li lokela ho tsotelloa.
Nako ea infusion e lokela ho ba ka tekanyo ea lihora tse 0.5 bakeng sa ho kenngoa ha moriana oa 200 mg.
Tekanyetso e khothalelitsoeng: tšoaetso e itekanetseng - makhetlo a 200 mg makhetlo a 2 ho kokota, e matla - makhetlo a 400 mg makhetlo a 2 ka letsatsi. Nako ea kalafo ke matsatsi a 7-14 kapa ho feta.
A gonorrhea e hlobaetsang, mokuli o fuoa 100 mg hang.
Thibelo ea ts'oaetso ea ts'ebetso ea postoperative e etsoa ka ho tsamaisa 200-500 mg ea moriana oa lihora tse 0.5-1 pele o buuoa.
Litaelo tse khethehileng
Ka lebaka la kotsi ea litlamorao ho tsoa ho tsamaiso ea methapo e bohareng, bakuli ba nang le nalane ea ho ts'oaroa, ho ts'oaroa, lefu la sethoathoa, ho senyeha ha bokong ba mmele, le methapo ea methapo ba ka fuoa Ziprolet feela ka mabaka a bophelo bo botle.
Haeba letšollo le matla le le lelelele le hlaha nakong ea kalafo, ho hlokahala hore ho kenyele boteng ba pseudomembranous colitis, haeba ho netefatsa tlhahlobo, ho tlosa matlapa le tharollo hang-hang lia hlokahala.
Ka lebaka la ho ruruha ha methapo kapa ho phatloha ha bona ka lebaka la tšebeliso ea litlhare le tharollo ea moriana, kalafo e lokela ho emisoa ha ho hlaha matšoao a pele a tendovaginitis kapa bohloko bo ka har'a tendon.
Tsamaiso ea molomo le ea botsoali ea lithethefatsi e lokela ho tsamaisana le ho kenella ha metsi a lekaneng ho bakuli ba nang le diuresis e tloaelehileng.
Nakong ea kalafo, ho khothalletsoa ho qoba khanya ea letsatsi ka kotloloho.
Se ke oa roala lilense tsa puisano ha u sebelisa marotholi.
Marotholi a mahlo a ke ke a kenella ka kamoreng e ka ntle ea leihlo kapa subconjunctivally.
Ka tšebeliso e tšoanang ea tharollo ea tse ling tsa mahlo, karohano lipakeng tsa lits'ebetso e lokela ho ba metsotso e 5 kapa ho feta.
Ts'ebeliso ea Tsiprolet e na le tšusumetso e mpe ho bokhoni ba mokuli ho khanna likoloi le mekhoa.
Ho sebelisana le lithethefatsi
Ka tšebeliso e tšoanang ea Cyprolet:
- didanosine e fokotsa ho amoheloa ha ciprofloxacin,
- theophylline e ka phahamisa mahloriso a plasma le kotsi ea ho ba le chefo ea eona,
- meriana e nang le aluminium, zinc, iron kapa magnesium ion, le li-antacid e ka fokotsa ho amoheloa ha ciprofloxacin, ka hona nako ea ho nka meriana ena e lokela ho ba bonyane lihora tse 4,
- cyclosporin e ntlafatsa katleho ea eona,
- li-antimicrobials tse ling (aminoglycosides, beta-lactams, clindamycin, metronidazole) li baka tšebelisano,
- Lithethefatsi tse seng khahlanong le ho hlaseloa ke marang-rang (ntle le acetylsalicylic acid) li eketsa monyetla oa ho tsietsana,
- metoclopramide e potlakisa ho amoheloa ha ciprofloxacin,
- li-uricosuric agents li eketsa bongata ba plasma ea ciprofloxacin,
- anticoagulants e sa tobang e ntlafatsa phello ea eona, e lelefatsa nako ea ho tsoa mali.
Khokahano e khothalelitsoeng bakeng sa kalafo ea mafu a itseng:
- ts'oaetso e hlahisoang ke Pseudomonas spp: azlocillin, ceftazidime,
- Ts'oaetso ea streptococcal: meslocillin, azlocillin le lithibela-mafu tse ling tsa beta-lactam,
- tšoaetso ea staph: isoxazolylpenicillins, vancomycin,
- ts'oaetso ea anaerobic: metronidazole, clindamycin.
Acidity (pH) ea tharollo ea infusion ea ciprofloxacin ke 3.5-4.6, ka hona, ha e lumellane ka litlama le tharollo ea litokisetso le litokisetso tse sa tsitsang. Bakeng sa tsamaiso ea iv, ho ke ke ha khoneha ho kopanya le tharollo le pH e fetang 7.
Litšoantšiso tsa Ciprolet ke: matlapa - Ciprofloxacin, Cifran, Ciprinol, Ciprobay, tharollo - Ififpro, Ciprobid, Quintor, marotholi - Cipromed, Rocip, Ciprofloxacin-AKOS.
Matlapa le tharollo ea infusion
Mafu a tšoaetsanoang le a tšoaetsanoang a bakoang ke likokoana-hloko tse ikhathatsang haholo ho ciprofloxacin.
- tšoaetso e tlase ea phefumoloho (pneumonia, bronchiectasis, bronchitis e mpe le ho mpefatsa ha bronchitis e sa foleng, mathata a tšoaetsanoang a cystic fibrosis),
- Ts'oaetso ea ENT (sinusitis e hlobaetsang),
- ts'oaetso ea liphio le pampitšana ea urinary (cystitis, pyelonephritis),
- tšoaetso ea lefutso
- tšoaetso ea baktheria ea mpa ea ka mpeng (lesapo la mokokotlo, pampitšana ea mala),
- ts'oaetso ea letlalo le lisele tse bonolo: li-ulc tse nang le tšoaetso, maqeba, ho chesa, ho ruruha, phlegmon,
- tšoaetso e bakoang ke ho se sebetse hantle ha o ntse o nka li-immunosuppressants, hammoho le ho bakuli ba nang le neutropenia,
- sepsis
- peritonitis
- ts'oaetso ea masapo le manonyeletso: ramatiki, setericelitis,
- thibelo le kalafo ea anthrax ea pulmonary.
Bana ba lilemo tse 5 ho isa ho 17:
- Phekolo ea mathata a bakoang ke Pseudomonasaeruginosa ho bana ba nang le pulmonary cystic fibrosis,
- thibelo le kalafo ea anthrax ea pulmonary (Bacillusanthracis).
Ho ekelletsa moo, bakeng sa tharollo ea infusion: ts'oaetso e rarahaneng ea ka mpeng (hammoho le metronidazole), ho kenyelletsa shigellosis, letšollo la baeti, feberu ea typhoid, peritonitis, campylobacteriosis, thibelo ea ts'oaetso nakong ea ts'ebetso ea ho buoa.
Leihlo la theoha
Mafu a tšoaetsanoang leihlo le mahlaseli a lona a bakoang ke likokoana-hloko tse amehang ho moriana:
- conjunctivitis a hlobaetsang le e subacute,
- blepharoconjunctivitis,
- blepharitis
- li-ulne tsa likokoana-hloko
- baker keratitis le keratoconjunctivitis,
- dacryocystitis e sa foleng le meibomites.
Thibelo le kalafo ea mathata a tšoaetsanoang kamora ho buuoa, likotsi, 'mele e kantle ho naha.
Foromo ea litekanyetso
Matlapa a koahetsoeng, 250 mg, 500 mg
Letlapa le leng le na le
ntho e sebetsang - ciprofloxacin 250 mg kapa 500 mg,
baamohelang: starch ea lijo-thollo, cellcose ea microcrystalline, sodium ea croscarmellose, colloidal silicon dioxide, talc e hloekisitsoeng, magnesium stearate,
Ho hlophisoa ha khetla: hypromellose, sorbic acid, titanium dioxide, lesaka le hloekisitsoeng, macrogol (6000), polysorbate 80, dimethicone.
Matlapa a koahetsoeng ka tšoeu a chitja, a na le biconvex bokaholimo le boreleli mahlakoreng ka bobeli, a bophahamo (4.10 0.20) mm le bophara (11.30 0.20) mm (bakeng sa litekanyetso tsa 250 mg) kapa bolelele (5.50 0.20) mm le bophara. 12.60 0.20) limilimithara (bakeng sa litekanyetso tsa 500 mg).
Melemo ea pharmacological
Mofumahali
Ka potlako e tsoang ka mpeng ea gastrointestinal. Ho bioavailability kamora tsamaiso ea molomo ke 70%. Ho ja hanyane ho ama ho kenngoa ha ciprofloxacin. Boemo ba plasma ba khatello ea liprofloxacin bakeng sa tsamaiso ea molomo bo tšoana le ba tsamaiso ea methapo, ka hona, mekhoa ea tsamaiso ea molomo le e kenang e ka nkoa e fetoha. Puisano le liprotheine tsa plasma ke 20 - 40%. Ho felisoa ha halofo ea bophelo ba ciprofloxacin ke lihora tse 6 ho isa ho tse 8 ka mor'a tekanyo e le 'ngoe kapa tse ngata. Ciprofloxacin e kenella hantle ka har'a litho le lisele: matšoafo, mucous membrane ea bronchi le sputum, litho tsa tsamaiso ea genitourinary system, ho kenyeletsa le tšoelesa ea senya, masapo a masapo, mokelikeli oa "cerebrospinal" le polocorphonuclear leukocytes, li-macrophages tsa alveolar. E ajoa haholo ka moroto le bile.
Mofumahali
Ciprolet® ke lithibela-mafu tse pharalletseng tse tsoang sehlopheng sa fluoroquinolones. E hatella DNA ea baktheria gyrase (topoismerases II le IV, e ikarabellang ts'ebetsong ea ho phahama ha DNA ea chromosomal ho potoloha RNA ea nyutlelie, e hlokahalang bakeng sa ho bala tlhaiso-leseling ea lefutso), e senya tlhahiso ea DNA, kholo ea baktheria le karohano, e baka liphetoho tse boletsoeng morphological (ho kenyeletsa le lerako la lisele le li-membrane) le lefu le potlakileng la sele ea kokoana-hloko. E sebetsa ho likokoana-hloko tse mpe tsa gram nakong ea dormancy bactericidal le nakong ea karohano ea bactericidal (hobane ha e ame feela gyrase ea DNA, empa e boetse e baka lysis ea lebota la sele), 'me ho li-microorganisms tse ntle tsa gram ke bactericidal feela nakong ea karohano. Ho ba le chefo e fokolang ho lisele tsa macroorganism ho hlalosoa ke ho haella ha li-gyrase tsa DNA ho tsona. Ciprolet® e sebetsa khahlano le mefuta e mengata ea likokoana-hloko kavitro le kavivo:
- likokoana-hloko tse ntle tsa aerobic gram: Corynebacterium diphtheriae, Enterococcus faecalis, Listeria monocytogene, Staphylococcus spp. Ho kenyelletsa Staphylococcus aureus, epidermidis, Streptococcus pyogene, agalactiae, pneumoniae, Streptococcus (lihlopha C, G), Virid group.
- likokoana-hloko tse mpe tsa aerobic gram-negative: Acinetobacter spp. Ho kenyelletsa Acinetobacter anitratus, baumannii, calcoaceticus, Actinobacillus Actinomycetemcomitans, Bordetella pertussis, Citrobacter freundii, diversus, Enterobacter spp. parainfluenzae, Helicobacter pylori, Klebsiella spp. Salmonella spp., Serratia spp., E kenyeletsa Serratia marcescens,
- likokoana-hloko tsa anaerobic: Bifidobacterium spp., Clostridium perfringens, Fusobacterium spp., Peptostreptococcus, Propionibacterium spp., Veillonella spp.,
- likokoana-hloko tse Intracellular: Streptococcus pneumoniae, Enterococcus faecalis, Chlamydia pneumoniae, psittaci, trachomatis, Legionella spp. Ho kenyelletsa le Legionella pneumophila, Mycobacterium spp. Ho kenyelletsa Mycobacterium leprae, lefuba, Mycoplasma pneumoniae.
Ciprolet® e hanyetsa Ureaplasma urealyticum, Clostridium Hardile, Nocardia asteroids, Bacteroides fragilis, Pseudomonas cepatica, Pseudomonas maltophilia, Treponema pallidum
Matšoao a ho sebelisoa
Ts'oaetso e sa rarahanang le e rarahaneng e bakoang ke likokoana-hloko tse utluoang ke ciprofloxacin:
- tšoaetso ea litho tsa ENT (atitis media, sinusitis, frontal sinusitis, mastoiditis, tonsillitis)
- ts'oaetso ea phepelo e tlase ea ho hema e bakiloeng ke libaktheria tse mpe tsa gram tse senngoeng ke Klebsiella spp., Enterobacter spp., Proteus spp., Esherichia coli, Pseudomonas spp., Haemophilus spp. Branhamella spp., Legionella spp, Staphylococcus spp. (ho mpefala ha lefu le sa foleng la pulmonary lefu, tšoaetso ea bronchopulmonary le cystic fibrosis kapa bronchiectasis, pneumonia)
- tšoaetso ea pampitšana ea urinary (e bakoang ke gonococcus urethritis le cervicitis)
- tšoaetso ea thobalano e bakiloeng Neisseriagonorrhoeae (gonorrhea, chancre e bonolo, urogenital chlamydia)
- epidemiitis orchitis, ho kenyelletsa linyeoe tse bakoang ke Neisseriagonorrhoeae.
- ho ruruha hoa litho tsa pelvic ho basali (mafu a ho ruruha a pelvis), ho kenyelletsa le linyeoe tse bakoang ke Neisseria gonorrhoeae
- tšoaetso ea ka mpeng (tšoaetso ea baktheria ea mothapo oa ka mpeng kapa phepelo ea methapo, peritonitis)
- tšoaetso ea letlalo, lisele tse bonolo
- septicemia, bacteremia, ts'oaetso kapa thibelo ea ts'oaetso ho bakuli ba nang le ts'oaetso e fokolang (mohlala, ho bakuli ba nkang li-immunosuppressants kapa ba na le neuropenia)
- thibelo le kalafo ea anthrax ea pulmonary (ts'oaetso ea Bacillus anthracis)
- tšoaetso ea masapo le manonyeletso
Bana le bohlankana
- kalafo ea mathata a bakoang ke Pseudomonas aeruginosa ho bana ba lilemo tse fetang 6 ka cystic fibrosis
- ts'oaetso e rarahaneng ea moetsana oa urine le pyelonifrita
- thibelo le kalafo ea anthrax ea pulmonary (ts'oaetso ea Bacillus anthracis)
Tekanyetso le tsamaiso
Matlapa a Ciprolet® a ngoletsoe batho ba baholo ka molomo, pele ho lijo kapa pakeng tsa lijo, ntle le ho hlafuna, a noe metsi a mangata. Ha e nkoa ka mpeng e se nang letho, ntho e sebetsang e kenella ka potlako. Litafole tsa Ciprofloxacin ha lia lokela ho nkoa ka lihlahisoa tsa lebese (mohlala, lebese, yogurt) kapa lino tse nang le litholoana ka kenyelletso ea liminerale.
Litekanyetso li beoa ka semelo le bosholu ba ts'oaetso, le kutloisiso ea pathogen e belaelloang, ts'ebetso ea liphio tsa mokuli, le ho bana le bacha, ho nahaneloa boima ba 'mele oa mokuli.
Tekanyetso e hlahisoa motheong oa letšoao, mofuta le botebo ba ts'oaetso, kutloelo-bohloko ea ciprofloxacin, kalafo e itšetlehile ka ho teba ha lefu lena, hammoho le lits'ebetso tsa kliniki le tsa baktheria.
Molemong oa phekolo ea tšoaetso e bakoang ke baktheria e itseng (k.k.,Pseudomonas aeruginosa, Acinetobacter kapa Stafilococ) Ho hlokahala litekanyetso tse phahameng tsa ciprofloxacin 'me li ka kopanngoa le litlhare tse ling tsa antibacterial tse nepahetseng.
Phekolo ea mafu a itseng (jk., Lefu la ho ruruha ha pelvic ho basali, ts'oaetso ea mahlaba ka mpeng, ts'oaetso ho bakuli ba nang le neutropenia, ts'oaetso ea masapo le manonyeletso), ho kopana hoa litlhare tsa antibacterial tse le 'ngoe ho ka etsahala, ho ipapisitse le likokoana-hloko tse fokolang tsa pathogenic tse li bakang. Setlhare se khothalletsoa litekanyetso tse latelang:
Matšoao
Mofuta oa letsatsi le letsatsi oa Mg
Nako ea kalafo kaofela (ho kenyelletsa le monyetla oa kalafo ea pele ea botsoali ka ciprofloxacin)
Tšoaetso e tlase
2 x 500 mg ho
Matsatsi a 7 ho isa ho a 14
Mafu a tšoaetsanoang ka ho fetesisa a phefumoloho
Ho eketseha ha sinusitis e sa foleng
2 x 500mg ho
Matsatsi a 7 ho isa ho a 14
Ramatiki e sa feleng ea tšehetso ea maikutlo
2 x 500mg ho
Matsatsi a 7 ho isa ho a 14
Malignant otitis externa
Ho tloha matsatsing a 28 ho isa ho likhoeli tse 3
Tšoaetso ea pampitšana ea urinary
2 x 500mg ho 2 x 750mg
basali nakong ea ho khaotsa ho ilela khoeli - hang 500 mg
Cystitis e rarahaneng, pyelonephritis e sa rarahanang
2 x 500mg ho 2 x 750mg
Bonyane matsatsi a 10 maemong a mang (mohlala, ka li-abscesses) - ho fihlela matsatsi a 21
2 x 500mg ho 2 x 750mg
Libeke tse 2-4 (a hlobaetsang), libeke tse 4 (tse sa feleng)
Tšoaetso ea lefutso
Fungal urethritis le cervicitis
tekanyetso e le 'ngoe 500 mg
Orchoepididymitis le mafu a tšoaetsanoang a litho tsa kahare
2 x 500mg ho 2 x 750mg
e seng ka tlase ho matsatsi a 14
Ts'oaetso ea ka mpeng le tšoaetso ea methapo
Letšollo le bakoang ke tšoaetso ea baktheria, ho kenyelletsa Shigella sppntle le Shigella dysenteriae mofuta oa I le kalafo e matlafatsang ea letšollo le matla la moeti
Letšollo le bakoang ke Shigella dysenteriae thaepa I
Matlapa a meriana a Ciprolet (ciprofloxacin) - a thusa ho tsoa ho eng
Ho na le mafu a mangata ao ho sebelisoang matlapa a Ciprolet. Ho tsoa ho seo ba se thusang:
- Ts'oaetso ea ENT e bakoang ke ts'oaetso,
- Tracheitis, bronchitis, pneumonia,
- Cystitis, glomerulonephritis, pyelonephritis, ho ruruha ha ureters,
- Marang-rang a tšoaetso ea kokoana-hloko, baktheria ka tlhaho,
- Marapo a tšoaetsanoang a masapo le manonyeletso,
- Maloetse a ka mpeng
- Ho ruruha le ho matlafatsa letlalo.
Sebopeho sa moriana
Ho sebelisa litlhare | Boima mg |
Likarolo tsa mantlha | |
Cyproxacin hydrochloride | 291,106 |
Starch | 50,323 |
Magnesium stearate | 3,514 |
Colloidal silicon dioxide | 5 |
Talcum phofo | 5 |
Sodium ea Croscarmellose | 10 |
Microcrystalline cellulose | 7,486 |
Hypromellose | 4,8 |
Tekanyetso ea titanium | 2 |
Talcum phofo | 1,6 |
Macrogol 6000 | 1,36 |
Sorbic acid, polysorbate 80, dimethicone | 0.08 mg ka 'ngoe |
Tsiprolet le Tsiprolet A: na ho na le phapang
Ciprolet ke lithibela-mafu tse sebelisang lithethefatsi tse le 'ngoe, ho tloha ka nako eo
Hobaneng matlapa a Cyprolet A a hlalositsoe karolong ee
ciprofloxacin e sebetsa e le eona feela karolo e sebetsang ea moriana ona.
Ciprolet A e nkoa e le sethethefatsi se kopaneng. E na le lintho tse peli tse sebetsang - ciprofloxation 500 mg le tinisadol 600 mg.
Motsoako ona o etsa hore e atlehe haholo kalafong ea mefuta e fapaneng ea ts'oaetso ea mofuta o kopaneng, ha likokoana-hloko tse bonolo li hoketsoe ho tsona. Lethathamo la likhothaletso le lipontšo tsa ho amoheloa ho Tsiprolet le Tsiprolet A le tsona li tšoana, ke oa bobeli feela o sebelisoang kalafong ea methapo e matla le e tsoetseng pele ea maloetse a baktheria.
Letlapa la cyprolet 250, 500 mg: litaelo tsa tšebeliso
Matlapa a tlameha ho nooa ka molomo ka mpa e tletse, a hlatsoe ka metsi a fokolang. Ha ho kenoa ka mpeng e se nang letho, motsoako o sebetsang o monya kapele haholo.
Nako ea ho amoheloa e khethoa ke matšoao a mangata:
- ntshetsopele ya lefu lena
- mofuta oa ts'oaetso
- ka lilemo
- boemo ba ho se sireletsehe
- likarolo tsa liphio le sebete.
Phekolo ea antibacterial ha e emise ka mor'a ho tlosa matšoao a sithabetsang, ho khothalletsoa ho nka matlapa bakeng sa matsatsi a mang a 2-3. Nako ea kalafo e khethoa ke ngaka e eang.
Mokhoa oa ho noha Tsiprolet: litekanyetso
Tekanyetso e khothalletsoang bakeng sa batho ba baholo:
Mefuta ea maloetse | Tekanyetso e le 'ngoe (mg) | Re amohela ka letsatsi | Koetliso Nako e nka matsatsi |
Bonolo ho leka-lekanya tšoaetso ea phepelo ea mocheso e tlase | 500 | 2 | 7-14 |
Tšoaetso e matla ea tlase ea phefumoloho | 750 | ||
Sinusitis e hlobaetsang | 500 | 10 | |
E bonolo ho isa ho a mang tšoaetso ea letlalo le lisele tse bonolo | 7-14 | ||
Ho ruruha ho matla ha ts'oaetso ea letlalo le lisele tse bonolo | 750 | ||
Ho bonolo ho tšoaetso e leka-lekaneng ea masapo le manonyeletso | 500 | 28-42 | |
Tšoaetso e matla ea masapo le manonyeletso | 750 | ||
Maloetse a tšoaetsanoang ka urinary ea mafu a tšoaetsanoang | 250-500 | 7-14 | |
Cystitis e sa rarahanang | 3 | ||
Mofuta o sa foleng oa prostatitis | 500 | 28 | |
Kokonate e sa sebetseng | 250-500 | 1 | 1 |
Letšollo le sa sebetseng | 500 | 2 | 5-7 |
Mofuta oa feberu ea typhoid | |||
E le prophylaxis ea litlamorao tsa ho buuoa | 250-500 | 7 | |
Ka kalafo ea sepsis le peritonitis | 500 | Mong le e mong lihora tse 12 | 7-14 |
Joaloka prophylaxis ea koatsi ka sebopeho sa pulmonary | 500 | 2 | 60 |
Tšoaetso ka morao ho ts'ireletso ea mmele e hatelletsoeng (litlamorao tse bileng teng nakong ea kalafo ka lithethefatsi tse hatellang boits'ireletso ba mmele kapa neutropenia). | 250-500 | 28 |
Cyprolet ho meno
Ciprolet e sebelisoa haholo ho tsa meno le lithethefatsi tse ling tsa antibacterial. Litafole tsa moemeli enoa ea antibacterial li thusa khahlano le mefuta e fapaneng ea ho ruruha le tšoaetso.
Lingaka li re li boetse li sebetsa hantle molemong oa ho thibela phetelo ea maikutlo kamora ho buuoa.
Kamora ho ntšoa leino
Pheko ea antibacterial ea hlokahala kamora ho nts'oa leino, leha ho le joalo, ka leihlo la ngaka ea meno, e ka hlakoloa kapa ea se sebelisoe ho hang haeba ho tlosa ho ne ho se bonolo. Matlapa a Ciprolet a laetsoe hore a sebelisoe ka nako ea matsatsi a 5 ka makhetlo a 2 ka letsatsi, Letlapa le le leng, le fokotsang kotsi ea ho ruruha, ho fokotseha le tšoaetso.
Bakeng sa leino le opang
Setlolo se bitsoang Ciprolet ha se kena 'meleng se qala ho kenella ka matla maling. Lipilisi li felisa bohloko ka potlako, li kokobetse ho ruruha le ho senya likokoana-hloko. Moriana ona o nka lihora tse 4-5, ka mor'a moo o pepesetsoa liphio, 'me o se o tumme le ho sebelisoa ka bongata.
Lithibela-mafu li sebetsa hantle bakeng sa flux methating ea pele, ha lekhopho le e-so hlahe, ebe Ciprolet e lokela ho sebelisoa feela kamora ho bula sebopeho. Thupelo e tloaelehileng ea kalafo ke matsatsi a 5, Letlapa le le leng ka mor'a lihora tse 12.
Cyprolet e nang le bronchitis
Maemong moo sesosa sa bronchitis ke tšoaetso ea baktheria, ke hore, lebaka la ho khethoa ha kalafo ea lithibela-mafu. Ha pus e hlaha sputum kapa e na le bronchitis e lulang e ipheta, ho boetse ho fanoa ka lithibela-mafu. Monyetla mona o fuoa matlapa.
Ciprolet e thusa hantle methating ea pele ea bronchitis kapa ha lithethefatsi tse ling li se na thuso. Nako ea kalafo le litekanyetso li beoa kamora tlhahlobo le ho buisana le ngaka. Hangata, Tsamaiso ea Ciprolet ha e nke matsatsi a fetang 10, Letlapa le le leng makhetlo a mabeli ka letsatsi.
Le angina
Maemong a kotsi a "purulent tonillitis" le "allergies" ho li-antibacterial agents, ho ngotsoe matlapa a Ciprolet, a etsang hore e be a bohlokoa kalafong ea lefu lena. Khafetsa, ka sebopeho se matla sa angina, lithethefatsi tse thibelang likokoana-hloko tsa penicillin le li-macrolide ha li na matla.
Ka angina e matla, Ciprolet e sebelisoa ka mokhoa oa tharollo ea infusion.
Motsoako o khothalelitsoeng oa lithethefatsi matlapeng ho motho e moholo molemong oa kalafo ea tonsillitis ke halofo ea letlapa makhetlo a 2 ka letsatsi. Tšoaea lithethefatsi ho tloha matsatsing a 7 ho isa ho a 10.
Bakeng sa liforomo tse matla, matlapa a 1-1.5 a behiloe makhetlo a 2-3, hape le matsatsi a 7- 7. Ha matšoao a kula a se a sa sebetse hantle, moriana o ntse o nkuoa matsatsi a mang a 3. Bakeng sa tonsillitis ea purulent, moriana o fanoa ka tekanyetso e le 'ngoe ka nako ea libeke tse 3-4, e le ho thibela mathata.
Moriana oa Ciprolet o nang le sinusitis
Cyprolet e nang le sinusitis e sebelisoa ha tšoaetso ea baktheria e khomaretse ho eona. Setlhare sena se na le litlamorao, ho tloha moo se sebelisoa maemong a moo kalafo le meriana e meng e sa sebetseng.
Batho ba baholo ba khothaletsoa ho nka letlapa le le leng la 1 la Chiprolet makhetlo a mabeli ka letsatsi bakeng sa matsatsi a 5-7, ho latela botebo ba lefu lena.
Cyprolet ho gynecology bakeng sa cystitis ho basali
Yproletlet e ka nkuoa boemong bofe kapa bofe le cystitis efe kapa efe. Pilisi e fanoa ke ngaka ho latela lintlha tsa mokuli - lilemo, boima, le boima ba lefu lena le ho ba teng ha mafu a kopaneng.
Motsoako o khothalelitsoeng oa kalafo ea cystitis ho basali ke matlapa a mabeli ka letsatsi le khefu ea lihora tse 12. Thupelo ena e nka matsatsi a 5 ho isa ho a 14. Litsebi li eletsa basali ba nang le bothata ba ho se sebetse ka liphio ho fokotsa tekanyo ea lithethefatsi ka makhetlo a 2.
Ka prostatitis
Ka sebopeho se matla sa prostatitis, tsamaiso ea sethethefatsi Ciprolet e laetsoe ke mokhoa oa ho hlakisa molomo, kamora hore e fetise mohato oa ho hlakola, ho ngoliloe matlapa. Ho fetohela ho mofuta oa tsamaiso ea molomo ho ka etsahala ka letsatsi la 4 la thuto ea ente.
Motsoako o khothalletsoang oa banna ba nang le prostatitis ke 500 mg lihora tse ling le tse ling tse 12. Kamohelo e nka matsatsi a 10, e ka atolosoa ka maikutlo a ngaka. Ho bohlokoa hape ho tseba hore boteng ba ho hlohlona ha liphio kapa sebete, moriana oa Ciprolet o lokela ho fokotsoa makhetlo a 2.
Cyprolet bakeng sa bana: litaelo tsa ho li sebelisa
Lithibela-mafu ha li lumelloe ho bana nakong ea kholo e mafolofolo ho fihlela lilemo tse 18.
Haeba setšoantšo sa kliniki ea lefu lena se rarahane, joale ho nka Ciprolet ho lumelloa ka tlasa tlhokomelo ea bongaka e matla ho tloha lilemong tse 15, athe litekanyetso li tlameha ho baloa le ho fetoloa ka bonngoe.
Motsoako o khothalelitsoeng oa ho felisa mathata a hlahisoang ke Pseudomonas aeruginosa ho bana ba nang le muscid pulmonary fibrosis maemong a lilemo tse 5-17 ke 20 mg ka boima ba kilo e le 'ngoe ka lihora tse 12 (tekanyetso e kholo ea letsatsi le letsatsi bakeng sa ngoana ha ea lokela ho feta 1500 mg). Thupelo ena e nka matsatsi a 10-14.
Bakeng sa kalafo le thibelo ea koatsi ka mofuta oa pulmonary, o hloka ho nka 15 mg ka boima ba kilo e le 'ngoe ho boima ba' mele ka lihora tse 12. Tekanyo e phahameng ka ho fetisisa bakeng sa tekanyetso bakeng sa ngoana ha ea lokela ho ba ho feta 500 mg, mme tekanyetso ea letsatsi le letsatsi ha ea lokela ho feta 1000 mg. Thupelo ena e nka matsatsi a 60.
Litlamorao
Litla-morao ha o ntse o sebelisa moriana o ka bonoa ho tloha mahlakoreng:
Tšilo ea lijo | Tsamaiso ea methapo | Mekhoa ea pono | Tsamaiso ea pelo | Lisebelisoa tsa Hematopoietic | Matšoao a laboratori | Tsamaiso ea methapo | Litla-morao | Sistimi ea musculoskeletal | |
1 | ho nyekeloa | ho tsekela | ho sitisa kutlo | ho theola khatello ea mali | phokolo ea mali | hyperglycemia | ho bolokoa ka moroto | ho hlohlona | ramatiki |
2 | lets'ollo | hlooho e bohloko | tinnitus | tachycardia | thrombocytopenia | hypoprothrombinemia | polyuria | urticaria | Riptures ea tendon |
3 | ho hlatsa | mokhathala | ho sitisoa hoa pono | phallo ea mali letlalong la sefahleho | leukopenia | hypercreatininemia | dysuria | mali a tsoang | myalgia |
4 | bohloko ba ka mpeng | maemo a ho tšoenyeha | tlolo ea molao | morethetho oa pelo | granulocytopenia | hyperbilirubenimia | albinuria | feberu ea lithethefatsi | tenosynovitis |
5 | botlaela | ho hloka boroko | pherekano e sebetsang | leukocytosis | Urethral madi | petechiae (hemorrhages) | arthralgia | ||
6 | anorexia | thothomela | thrombocytosis | hematuria | ho ruruha ha sefahleho, larynx | ramatiki | |||
7 | hepatitis | bosiu | ea fokotseha tšebetso ea "nitrogen excretory" ea liphio | ho hema hanyane | |||||
8 | hepatonecrosis | Kameho e sa utloahaleng ea bohloko | krystalluria | photosensitivity | |||||
9 | jaundice | mofufutso | eosinophilia | ||||||
10 | khatello e eketsehileng ea intracranial | vasculitis | |||||||
11 | khatello ea maikutlo | erythema (nodular, exulative multiform, malignant exudative (Stevens-Johnson syndrome), | |||||||
12 | hallucinations | Lefu la Lyell. | |||||||
13 | migraines | ||||||||
14 | ho akheha |
Ntle le moo, ho ba teng ha bofokoli bo akaretsang le bonohe bo ka etsahala - candidiasis le pseudomembranous colitis.
Nka nka cyprolet nakong ea kemolo?
"Anti" e thibelang likokoana-hloko e bua ka lithethefatsi tse ngata tse thibetsoeng hantle nakong ea kemaro le nakong ea ho anyesa. Ciprolet ha e e-so leke basali ba baimana, ka hona, phello ea eona ho lesea ha e so ithutoe. Liteko li ne li etsoa ho liphoofolo feela.
Cyprolet le joala - papali: Na ho na le monyetla oa hore u noe
Ha o sebelisana le joala, motsoako oa li-enzyme tsa sebete tse sebetsanang le ethanol le lihlahisoa tsa lona tse bolileng lia emisa.
Ebe matšoao a botahoa a teba le ho lekana ha bona, chefo e matla e ba teng. Boleng ba bona bo angoa ke palo ea joala bo nooang le litšobotsi tsa 'mele.
Ho sebelisana le lithethefatsi tse ling
- ha e sebelisoa le lithethefatsi tse amang boemo ba acid ba lero la gastric (antacids), lihlahisoa tse nang le aluminium hydroxide, magnesium, letsoai la calcium, tšepe le zinki li ka thusa ho fokotsa ho amoheloa ha ciprofloxacin ke 'mele, kahoo o hloka ho boloka phomolo ho tloha lihora tse 1 ho isa ho tse 4 lipakeng tsa bona ,
- ha o nka theophylline, o hloka ho lekola ho ts'oaroa ha eona, hobane e ka nyoloha ka matla plasma ea mali,
- ha e nkuoa ka cyclosporine, maemong a mang, khatello ea serum creatinine e eketsehile,
- ha e nkuoa ka warfarin, phello ea ciprofloxacin e ile ea ntlafatsoa maemong a itseng,
- ka tekanyetso e phahameng ea li-quinols le tse ling tse seng tsa 'mele tse khahlanong le ho ruruha, maikutlo a ile a bonoa,
- lithethefatsi li ka kopantsoe nakong ea kalafo le azlocillin, ceftazidime, meslocillin, azlocillin, azxazoylpenicillins, vancomycin, metronidazole, clindamycin.
Tekanyetso le tsamaiso
Matlapa a tlameha ho nkuoa ka molomo (kahare), ho sa tsotelehe lijo, ka mokelikeli o fokolang. Matlapa a lokela ho metsoa a felletse ntle le ho hlafuna. Ha o nka Ciprolet ka mpeng e se nang letho, e kenella ka potlako, 'me ha ua lokela ho noa lithethefatsi ka lihlahisoa tsa lebese kapa lino tse matlafalitsoeng ka calcium. K'halsiamo e fumanehang ka har'a lijo ha e ame ho kenngoa ha moriana.
- tšoaetso ea pampitsana ea phefumoloho: 500-700 mg makhetlo a 2 ka letsatsi,
- ts'oaetso ea genitourinary system: a hlobaetsang, a sa rarahanang - 250-500 mg makhetlo a 2 ka letsatsi, cystitis ho basali (pele ho nako la ho khaotsa ho ilela khoeli) - 500 mg 1 nako, e rarahaneng - 500-750 mg makhetlo a 2 ka letsatsi, tšoaetso ea setho sa botšehali (ntle le gonorrhea) - 500 –750 mg makhetlo a 2 ka letsatsi, gonorrhea - 500 mg makhetlo a le 1 ka letsatsi, letšollo - 500 mg makhetlo a 2 ka letsatsi,
- tšoaetso e ngoe: 500 mg makhetlo a 2 ka letsatsi,
- tšoaetso e matla e behang bophelo kotsing (ho kenyelletsa le lefu lagazi la 'mellane la cycodcal, tšoaetso ea masapo le manonyeletso, septicemia, peritonitis): makhetlo a 750 mg makhetlo a mabeli ka letsatsi.
Lenaneo le khothaletsoang la dosing bakeng sa lihlopha tse khethehileng tsa bakuli:
- bakuli ba ka holimo ho lilemo tse 65: tekanyetso e lokela ho fokotsoa ho latela botebo ba lefu lena le tumello ea creatinine,
- ho se sebetse hantle haholo ka tumello ea "creatinine" ho tloha ho 30 ho isa ho 60 ml / min, tekanyo e phahameng ea ciprofloxacin ke 1000 mg / letsatsi, ka tumello ea creatinine ka tlase ho 30 ml / min - 500 mg / ka letsatsi, haeba mokuli a le hemodialysis, Ciprolet e lokela ho nkuoa ka mor'a eona. Bakeng sa li-outpatients tse ntseng li tsoela pele ho etsa peritoneal dialysis, lethal dose le phahameng la letsatsi le letsatsi la litekanyetso ke 500 mg.
- ho se sebetse hantle ha sebete: phetoho ea tekanyetso ha e hlokehe.
Nako ea kalafo e latela botebo ba lefu lena, taolo ea baktheria le ea bongaka. Kamora hore matšoao a nyamele, tsamaiso e hlophisitsoeng ea moriana e lokela ho tsoelapele bonyane matsatsi a 3 ho feta. Nako e tloaelehileng ea kalafo:
- gonorrhea e sa rarahanang, cystitis: 1 letsatsi,
- ts'oaetso ea liphio, mokhoa oa ho ntša metsi, ho kenella ka mpeng: ho fihlela matsatsi a 7,
- neutropenia ho bakuli ba immunocompromised: nako eohle ea bona,
- osteomyelitis: ha ho feta likhoeli tse peli,
- tšoaetso e 'ngoe: matsatsi a 7-14,
- tšoaetso e bakoang ke Streptococcusspp. le Chlamydiaspp: bonyane matsatsi a 10.
Bakeng sa thibelo le kalafo ea anthrax ea pulmonary: 500 mg makhetlo a 2 ka letsatsi matsatsi a 60. Ho hlokahala ho qala ho nka moriana hang ka mor'a ts'oaetso (ho belaelloa kapa ho netefatsoa).
Bana le bacha
Ho khothalletsoa mokhoa o latelang oa litekanyetso (ntle le ha ho bonts'itsoe ka tsela e 'ngoe):
- kalafo ea mathata a bakoang ke Pseudomonas aeruginosa ho bana ba lilemo li 5-17 ka pulmonary cystic fibrosis: boima ba mmele ba 20 mg / kg makhetlo a 2 ka letsatsi (lethal dose le leholo la letsatsi le letsatsi - 1500 mg). Nako ea lithethefatsi ke matsatsi a 10-14,
- thibelo le kalafo ea anthrax ea pulmonary (Bacillus anthracis): boima ba mmele ba 15 mg / kg makhetlo a 2 ka letsatsi. Sekhahla se phahameng sa letsatsi ke 1000 mg. Nako ea lithethefatsi ke matsatsi a 60.
Eketsa tharollo ea infusion
Boitšoaro ba lehae bo ka etsahala: ka nako ea ho kenngoa ha nako e ka tlase ho metsotso e 30, edema e atile haholo (ts'oaetso ea letlalo le sa foleng). Boitšoaro bona bo etsahala ka mor'a ho felisoa ha ts'ebetso mme ha se ho sitisoa ts'ebeliso ea lithethefatsi hape (haeba tsela ea eona e sa rarahana).
Hoa hlokahala ho ela hloko litaba tsa sodium chloride ho tharollo ea bakuli ba nang le sodium e ngata.
Eketsa matlapa
Tsamaiso e kopanetsoeng ka litokisetso tsa cationic, liminerale tsa liminerale tse nang le tšepe, calcium, magnesium, sucralfate, antacids, polymer phosphate complication, aluminium, hammoho le litokisetso tse nang le bokhoni bo boholo ba buffer bo nang le magnesium, calcium, aluminium, e fokotsa ho amoheloa ha ciprofloxacin. Ntlheng ena, ho khothalletsoa ho e nka lihora tse 1-2 pele kapa lihora tse 4 kamora ho sebelisa meriana ena. Thibelo ena ha e sebetse sehlopheng sa li-blockers tsa H2-histamine receptor.
Lihlahisoa tsa lebese le lino tse ntlafalitsoeng ka liminerale ha lia lokela ho nkuoa ka nako e le 'ngoe le ciprolet, kaha li ka fokotsa ho amoheloa ha ciprofloxacin.
Tsifran kapa Tsiprolet: e leng betere
Tsifran ke analog ea Tsiprolet. E boetse e sebetsa khahlano le likokoana-hloko tse mpe tsa gram tse mpe tsa gram, fungus, vaerase, likokoana-hloko tsa syphilis le likokoana-hloko tse ling tsa anaerobic li e loantša.
Ka bobeli lithethefatsi li na le lipontšo le li-contraindication tse tšoanang.Ho fapana le Cifran, Ciprolet e sebelisana hantle le lithethefatsi tse ling.
Tsipromed kapa Tsiprolet: e leng betere
Tsipromed ke analog e 'ngoe ea Tsiprolet, ka sebopeho sa eona ke ntho e tšoanang. Lithethefatsi tsena tse peli li fapana ka theko - haeba marotholi a Ciprolet ke li-ruble tse 50-60 ka har'a k'hemiste, joale Cipromed e ka ba li-ruble tse 100-140. Cypromed e fumaneha ka mokhoa oa marotholi a tsebe le mahlo.
Lithethefatsi Ciprolet tse matlapeng li sebetsa hantle kalafong ea maloetse a fapaneng le lisele tsa baktheria, tseo ho tsona a sebelisoang ka thata ho tsa bongaka. Theko e tlase le ho fumaneha ho phahameng ha u khetha moriana o thibelang likokoana-hloko, lumella hore u mo etsetse khetho.