Thrombital le Cardiomagnyl: ke eng e betere?
Setlhare se hlahisoa ka mokhoa oa matlapa a koahetsoeng ka filimi: biconvex, pota, filimi e koahetsoeng le konokono mokokotlong oa lifapano tse ka bang bosoeu bo bosoeu kapa li-100 kapa li-100. ka sekotlolong sa khalase e lefifi (amber), e tiisitsoeng ka khoele e tšoeu e kentsoeng ka polyethylene e nang le sephutheloana se ntšitsoeng ka har'a silika le silika e fanang ka taolo ea ho buloa ha pele, ka lebokoseng la karete e le 'ngoe ea litaelo le litaelo tsa tšebeliso ea ntho e tsamaeang.
Letlapa le le leng le na le:
- Lintho tse sebetsang: acetylsalicylic acid - 75 mg, magnesium hydroxide - 15.2 mg,
- Lintho tse ling: starch ea litapole, cellulose ea microcrystalline, starch ea poone, magnesium stearate,
- Filimi e koahelang: macrogol (polyglycol 4000), hypromellose (hydroxypropyl methylcellulose 15 cPs), talc.
Mofumahali
Thrombital ke motsoako o kopantseng oa liplatelese tse kopaneng. Lithethefatsi ka lebaka la khatello ea tlhahiso ea thromboxane A lipulong tsa liplatelete2 e fokotsa ho kopanya, ho khokhotheha ka liplatelete, le popelo ea mali. Kamora tekanyetso e le 'ngoe, phello ea antiplatelet ea lithethefatsi e bonoa matsatsi a 7 (ho banna, phello e boleloa haholo ho feta ho basali).
Khahlano le semelo sa angina e sa tsitsang, acetylsalicylic acid e fokotsa lefu la motho le kotsi ea lefu la myocardial, e boetse e bonts'a katleho ts'ebetsong ea mantlha ea ho ruruha ha methapo ea pelo, haholo ho kenella ha myocardial ho banna kamora lilemo tse 40, mme e bonts'a sephetho se setle sa thibelo ea tlhaho ea myocardial. Ntho ena e sebetsang ka har'a sebete e thibela tlhahiso ea prothrombin, e khothaletsa ho eketseha ha nako ea prothrombin, keketseho ea ts'ebetso ea fibrinolytic ea plasma ea mali le ho fokotseha hoa boemo ba lintho tse amanang le ho tsitsisa tsa vitamini K - II, VII, IX le X. nakong ea ts'ebetso ea ts'ebetso, karolo e sebetsang e eketsa kotsi ea mathata a hemorrhagic, Khahlano le semelo sa tšebeliso e kopaneng le li-anticoagulants li eketsa monyetla oa ho tsoa mali.
Ha e sebelisoa ka tekanyetso e phahameng, acetylsalicylic acid e boetse e bonts'a lithibelo tse khahlanong le ho ruruha, li-analgesic le antipyretic, e etsa hore uric acid e tsoe (e sitisa ts'ebetso ea ho ts'oaroa ha eona ka har'a renal tubules). Ka mucosa ea ka mpeng, ho thijoa ha cycloo oxygenase-1 (COX-1) ho baka ho thibeloa ha li-prostaglandins tsa gastroprotential, tse ka lebisang ho ruruha ha mucosa le nts'etsopele e eketsehileng ea ho tsoa mali.
Hydroxide e kenyellelitsoeng ho hlophisoa ha magnesium thrombital e fana ka tšireletso ea mucosa ea gastrointestinal mucosa (GIT) liphellong tse mpe tsa acetylsalicylic acid.
Mofumahali
Acetylsalicylic acid e batla e nkiloe ka botlalo ho tsoa ho tšilo ea lijo. Half-life (T½) ntho e sebetsang e ka nka metsotso e 15, hobane tlasa ts'ebetso ea li-enzymes e potlakisa hydrolyzes ho salicylic acid e plasma ea mali, sebete le mala. Salicylic acid T½ e ka ba lihora tse 3, empa e ka eketseha haholo ka ts'ebeliso e le 'ngoe ea litekanyetso tse phahameng (tse fetang 3 g) tsa acetylsalicylic acid ka lebaka la tsamaiso ea enzyme. Bioavailability ea acetylsalicylic acid ke 70%, empa boleng bona bo ka feto-fetoha haholo, ka lebaka la hore ntho e sebetsang e hlahisoa ke kemiso ea hydrolysis (sebete, gastrointestinal mucosa) ka ho nka karolo ha li-enzyme ka salicylic acid, bioavailability ea eona e leng 80-100%.
Methapo ea magnesium hydroxide e sebelisitsoeng ha e ame bioavailability ea acetylsalicylic acid.
Matšoao a ho sebelisoa
- Thibelo ea mantlha ea ho ruruha ha pelo le masapo a pelo, ho kenyelletsa le likotsi tse teng (mohlala, khatello ea maikutlo, khatello ea maikutlo, lefu la tsoekere, ho tsuba, botena, botsofe),
- Thibelo ea mokokotlo oa mali le sekhahla sa mali,
- Thibelo ea thromboembolism kamora ho kenella ts'ebetsong ho likepe, joalo ka mokokotlo oa methapo ea methapo, ho potoloha ka tsela e poteletseng.
- angina pectoris.
Contraindication
- ho tsoa mali, ho ruruha le liso tsa liso tsa mpeng ea mpa ka nako ea ho mpefala,
- hemorrhage
- lefu la pelo le sa foleng la sehlopha sa IV - IV se sebetsang ho latela sehlopha sa NYHA (New York Association of Cardiology),
- Karolo e sa lekanyetsoang kapa e felletseng ea polyposis e sa khaotseng ea rhinosinusitis le lefu la bronchial le mamello ho li-acetylsalicylic acid kapa lithethefatsi life kapa life tse seng tsa mofuta oa li-antiidal (NSAIDs), ho kenyeletsa le cycloo oxygenase-2 inhibitors (COX-2), ho kenyelletsa nalane
- Asthma ea lefu la bronchial ka lebaka la ho kenella ha salicylates le NSAIDs tse ling,
- predisposition togazi (hemorrhagic diathesis, thrombocytopenia, khaello ea vithamini K),
- ho hloleha ho matla ha renal ka tumello ea creatinine (CC) ka tlase ho 30 ml / min,
- ho hloleha ho matla ha sebete (lihlopha tsa bana le bana tsa B),
- glucose-6-phosphate dehydrogenase ea haelloa,
- 'Na le III re hlokometse bokhachane le nako ea ho anyesa,
- Tšebeliso e tšoanang ea methotrexate ka lethal dose ea 15 mg ka beke kapa ho feta,
- lilemo tse 18
- hypersensitivity ho efe kapa efe dikarolo tsa lithethefatsi le NSAIDs tse ling.
E amanang (ho nka matlapa a bophelo bo botle ka hloko e kholo):
- nalane ea ho tsoa mali ka mpeng kapa likotsi tse amanang le ho ruruha ha ka mpeng,
- ts'ebetso ea ho senyeha ha lesapo (CC kaholimo ho 30 ml / min),
- ho hloleha ha sebete (Sehlopha sa bana-Pugh A),
- lefu la tsoekere
- mafu a sa foleng a amanang le ho hema, lefu la bronchial asthma, phofo ea nasal, maemo a kulang, ho kulisoa hoa lithethefatsi, ho kenyelletsa le mokhoa oa ho ama letlalo, ho hlohlona, urticaria (kaha acetylsalicylic acid e ka lebisa ho bronchospasm, hammoho le ho hlasela ha lefu la asthma ea bronchial kapa nts'etsopele ea liphetoho tse ling tsa hypersensitivity),
- gout, hyperuricemia, hobane acid e acetylsalicylic, e nkiloeng ka tekanyetso e nyane, e fokotsa phallo ea uric acid,
- II trimester ea bokhachane,
- ts'ebetso ea ho buuoa eo ho thoeng e kenyelletsoa (ho kenyelletsa le e nyane joalo ka ho ntšuoa leino), kaha ho thothomela ho ka baka mali matsatsi a 'maloa kamora ho e nka,
- botsofali
- Sebelisa hammoho le lithethefatsi tse latelang: Li-NSAIDs le litekanyetso tse phahameng tsa salicylic acid, digoxin, valproic acid, anticoagulants, antiplatelet / thrombolytic agents, methotrexate ka lethal dose le ka tlase ho 15 mg ka beke, li-insulin le li-activog tsa hypoglycemic (li-sulfonylurea-derivatives, serotonin uptake, ethanol (ho kenyeletsa le lino tse nang le ethanol), ibuprofen, systemic glucocorticosteroids (GCS), litokisetso tsa lithium, carbonic anhydrase inhibitors, sulfonamides, lithethefatsi RP G analgesics.
Thrombital, litaelo tsa tšebeliso: mokhoa le litekanyetso
Matlapa a Thrombital a nkuoa ka molomo, a hlatsuoa ka metsi, ka nako e le 'ngoe ka letsatsi. Haeba o na le bothata ba ho metsa letlapa lohle, o ka le hlafuna kapa oa le silakanya hore e be phofo.
Melemo ea moriana o khothalelitsoeng:
- Maloetse a pelo, ho kenyelletsa thrombosis le ho nyekeloa ke pelo haholo le lintho tse teng tse ka bang teng kotsing ea ho itšireletsa: ka letsatsi la pele - matlapa a 2, ebe Letlapa le le leng ka letsatsi.
- thromboembolism ka mor'a ho buuoa ka methapo, ho pheta-pheta ho hoholo ha myocardial le thrombosis ea methapo ea mali ka sepheo sa thibelo: lethal dose ea letsatsi le letsatsi ea matlapa a 1-2,
- angina e sa tsitsang: ka tekanyetso ea letsatsi le letsatsi ea matlapa a 1-2, bakeng sa ho monya ka potlako, Letlapa la pele la lithethefatsi le khothalletsoa ho hlafuna.
Thrombital e etselitsoe tšebeliso ea nako e telele, tekanyetso ea lithethefatsi le nako ea kalafo e khethoa ke ngaka e eang.
Nka moriana o hlokahala feela ho litekanyetso tse kaholimo ho latela lipontšo.
Litlamorao
- tsamaiso ea methapo: hangata - ho hloka boroko, ho opeloa ke hlooho, khafetsa - ho otsela, ho tsekela, ka seoelo - tinnitus, hemorrhage ea intracerebral, e nang le maqhubu a sa tsejoeng - tahlehelo ea kutlo (e ka ba sesupo sa tšebeliso e feteletseng ea lithethefatsi),
- hematopoietic system: khafetsa - ho tsoa mali ho eketsehileng (maqhubu a ho tsoa mali, nko ea mahlo, hematoma, ho tsoa mali ho tsoa liphatseng tsa lefutso), ka seoelo - khaello ea mali, hangata - thrombocytopenia, hypoprothrombinemia, aplasic anemia, neutropenia, eosinophilia, agranulocytosis, e nang le maqhubu a sa tsejoeng - Ho bile le litlaleho tsa linyeoe tse tebileng tsa ho tsoa mali (ka mohlala, joalo ka ho tsoa mali ka mpeng le hemorrhage ea mokokotlo, haholo-holo ho bakuli ba nang le khatello ea mali ea methapo ba sa kang ba fihlela. khatello ea mali le / kapa ho fumana kalafo e kopanetsoeng le lithethefatsi tsa anticoagulant), maemong a mang ho ba le motho ea behang bophelo kotsing, ho tsoa mali ho ka baka nts'etsopele ea khaello e matla kapa e sa foleng ea iron / anemia ea posthemorrhagic (mohlala, ka lebaka la ho tsoa mali) le matšoao a amanang le kliniki le a laboratori (pallor) , asthenia, hypoperfusion), ho bakuli ba nang le mefuta e matla ea khaello ea glucose-6-phosphate dehydrogenase, linyeoe tsa hemolysis le anemia ea hemolytic.
- Sistimi ea phefumoloho: khafetsa - bronchospasm,
- Sisteme ea urine: e nang le maqhubu a sa tsejoeng - ts'ebetso ea ho hlaka ea a amanang le lefu la masapo le ho hloleha ho hlaphoheloa ha methapo,
- tsamaiso ea tšilo ea lijo: hangata khafetsa - ho otla ha pelo, hangata - ho hlatsa, ho nyekeloa le pelo, bohloko - ka mpeng, liso tsa ka mpeng, ho kenyelletsa le mahlaba a ka mpeng, ho hlatsoa mali, seoelo - ketsahalo e eketsehang ea li-enzyme tsa sebete, tse sa tloaelehang haholo. - stomatitis, ho ruruha ha lesapo le kaholimo la mpa, maemo, esophagitis, colitis, lefu la masapo le bohale, le mokokotlo o sa tsejoeng - ho fokotseha takatso ea lijo, lets'ollo,
- litla-morao: hangata - urticaria, edema ea Quincke, hangata - mokhoa oa anaphylactic, ho kenyelletsa le angioedema, le maqhubu a sa tsejoeng - lekhopho la letlalo, ho hlohlona, ho ruruha ha mucosa ea nasal, rhinitis, lefu la pelo le khatello ea maikutlo, karabelo e matla, ho kenyelletsa ho ts'oaroa ke anaphylactic .
Ketsahalong ea ponahalo / ho mpefala ha litlamorao tse sa hlalosoang ka holimo kapa ho hlaha hoa litlolo tse ling, ho bohlokoa ho buisana le setsebi.
Bongata
Tekanyetso e feteletseng ea thrombital e ka lemohuoa ka bobeli ka mor'a tekanyetso e le 'ngoe ea lethal dose e phahameng, le kalafo ea nako e telele. Ka tekanyetso e le 'ngoe ea acetylsalicylic acid ka tekanyo e ka tlase ho 150 mg / kg, chefo e matla e nkuoa e le bonolo, ka tekanyo ea 150-300 mg / kg - e leka-lekaneng,' me ha e sebelisoa ho litekanyetso tse phahameng - tse matla.
Matšoao a bosholu ba lithethefatsi ho tloha ho bonolo ho isa tekanyong e matla a kenyelletsa: ho senyeha ha pono, ho se utloe litsebeng, hlooho, tinnitus, ho tsekela, mofufutso o eketsehileng, ho hlatsa, ho nyekeloa, ho nyefoloa ha pelo, tachypnea, pherekano, alkalosis ea ho hema. Ka nts'etsopele ea matšoao ana, a laetsoe ts'ebetso ea ho hlatsa le ho qobelloa ke li-alkaline diuresis, tšebeliso ea khafetsa ea khabone, 'me ho nkuoa mehato ea ho khutlisetsa tekano ea motlakase oa motlakase le boemo ba acid.
Matšoao a ho ata ha Thrombital ho tloha tekanyo ho isa ho a tebileng a ka kenyelletsa: mocheso o phahameng haholo oa 'mele (hyperpyrexia), alkalosis ea ho hema le khatello ea methapo ea methapo, hyperventilation, khatello ea phefumoloho, khatello ea methapo ea pelo, pherekano ea pelo, ho teba ha pelo , ho tsoa mali ka mpeng, tinnitus, ho se utloe litsebeng, hyperglycemia, hypoglycemia (haholo-holo ho bana), ketoacidosis, ho fokola hoa mmele, mosebetsi o fokolisang oa renal (ho tloha ho oliguria ho ea ho Nia renal insufficiency, hyper- le hyponatremia fapaneng, hypokalemia), thibelo ea tsamaiso ea bohareng methapo (otsela, sethoathoa, ferekane kelellong, coma), magazine nang le chefo e, mafu haematological (hatelloang tsa platelet aggregation ho coagulopathy, hypoprothrombinemia, e elongation ea nako prothrombin).
Haeba ho na le overdose e leka-lekaneng / e matla, ho hlokahala sepetlele hang hang bakeng sa kalafo ea tšohanyetso. Gastric lavage, tsamaiso e pheta-phetoang ea mashala a ts'ebetso le laxatives e etsoa, ka salicylates ho feta 500 mg / l, moroto o alkalized ke infravenous (iv) infusion ea sodium bicarbonate (88 meq ho tharollo ea glucose ea 5% ka tekanyo ea 1 l, ka tekanyo ea 10 -15 ml / kg / h). Diuresis ea kenyelletsoa mme bophahamo ba mali a potoloha bo khutlisoa (ka ho kenella ka makhetlo a mabeli kapa a mararo a kenngoa ka har'a sodium bicarbonate ka lethal dose le le leng). Re lokela ho hopola hore ho kenella ka matla ha mokelikeli ho bakuli ba tsofetseng ho ka baka edema ea pulmonary. Acetazolamide bakeng sa alkalization ea moroto ha e khothalletsoe, kaha e ka tsosa acidemia mme ea eketsa phello e chefo ea salicylates.
Ha o etsa dialis ea alkaline, ho hlokahala ho fihlela boleng ba pH pakeng tsa 7.5 le 8. Hemodialysis e beoa le pokello ea plasma ea li-salicylates maling a tse fetang 1000 mg / l, le ho bakuli ba nang le chefo e sa foleng - 500 mg / l kapa ka tlase ha ho bontšitsoe (ho tsoela pele ho mpefala, Reflexory acidosis, ho se sebetse hantle ha renal, edema ea pulmonary, senya e mpe ea methapo ea kutlo. Khahlano le semelo sa pulmonary edema, moea o kenelletseng oa matšoafo ka motsoako o matlafalitsoeng ke oksijene oa etsoa, ka edema ea methapo - hyperventilation le osmotic diuresis.
Tšokelo ea ho tahoa e sa foleng e eketseha haholo ho batho ba tsofetseng ha ba sebelisa matsatsi a mangata ka tekanyo e fetang 100 mg / kg ka letsatsi. Ho bakuli ba sehlopha sena sa lilemo, boemo ba li-salicylate ka plasma bo lokela ho khethoa nako le nako, hobane ha se kamehla ba khethang matšoao a pele a letsoalo, a joalo ka ho senyeha ha mahlo, tinnitus, ho nyekeloa, ho hlatsa, malaise ka kakaretso, hlooho, ho tsekela.
Litaelo tse khethehileng
Thrombital e lokela ho nkuoa joalo ka ha u laetsoe ke ngaka.
Tabeng ea ho nka acetylsalicylic acid ho litekanyetso tse fetisang kalafo, menyetla ea ho tsoa mali ka mpeng ea eketseha.
Khahlano le nalane ea ho nka acetylsalicylic acid nakong le / kapa ka mor'a ts'ebetso ea ho buuoa, nts'etsopele ea ho tsoa mali ka methati e fapaneng ea ho teba ho ka etsahala. Ho bakuli ba fumanang litekanyetso tse tlase tsa acetylsalicylic acid, matsatsi a 'maloa pele ho ts'ebetso e buelletsoeng ea ho buoa, ho a hlokahala ho lekola kotsi ea ho tsoa mali ha ho bapisoa le ts'okelo ea mathata a ischemic. Ka kotsi e kholo ea ho tsoa mali, moriana o lokela ho tloheloa ka nakoana.
Ka tšebeliso e le 'ngoe ea tšebeliso e ngata ea joala le joala, menyetla ea ho ba le mathata a mucosa a ka mpeng le ho tsoa mali ka nako e telele hoa eketseha.
Nakong ea kalafo ea nako e telele le sethethefatsi, tlhahlobo e akaretsang ea mali le tlhahlobo ea mali ea mohlolo e lokela ho etsoa nako le nako.
Bokhachane le pelehi
Ho trimesters ea I le III ea bokhachane, tšebeliso ea Thrombital e hanoa, kaha e na le phello ea teratogenic. Karolong ea pele ea bokhachane, tšebeliso ea lithethefatsi e ka lebisa ponahalong ea kharafu e kaholimo ho "fetus" le "trimester" ea boraro - ho thibela ts'ebetso (khatello ea methapo ea methapo ea methapo ea methapo) le methapo ea mali methapong ea methapo ea mali, ho koaloa kapele hoa ductus.
Asiti ea salicylic e feta sethaleng sa placental. Ho "trimester" ea Bobeli ea bokhachane, ho sebelisa moriana ho ka etsahala feela haeba molemo o lebelletsoeng ho mme o feta haholo ts'okelo ea bokhachane.
Acetylsalicylic acid, joalo ka metabolites ea eona, e fetela lebese la matsoele. Nakong ea ts'ebeliso ea thrombital, ho anyesa ho lokela ho emisoe.
Lifana tsa lifilimi tsa Thrombital le Cardiomagnyl
Tsena ke lihlahisoa tse nang le likarolo tse peli. Lithako tse sebetsang ka sebopeho sa tsona: acetylsalicylic acid (75-150 mg), magnesium hydroxide (15.2 kapa 30.39 mg).
Tšusumetso e ntle e fanoa ka lebaka la phello ea liplatelete. Mekhoa ea meriana e thibela ho kopana ha thromboxane A2, e fokotsang bokhoni ba liplatelete ho khomarela marako a methapo ea mali. Ka nako e ts'oanang, ho na le ho fokotseha ha mohato oa ho tlama lisele tsena tsa mali ho e mong, ho etsoa ha methapo ea mali ho thibetsoe, 'me methapo ea varicose le eona ke sesupo sa tšebeliso. Thepa ea antithrombotic e bonahatsoa nakong ea matsatsi a 7. Ho fihlela sephetho sena, ho lekane ho nka tekanyetso e le 'ngoe.
Letlotlo le leng la acetylsalicylic acid ke bokhoni ba ho ba le phello e ntle tsamaisong ea pelo le pelo. Ka kalafo ka ntho ena, ho na le phokotso ea menyetla ea lefu ka infraate ea myocardial. Setlhare se thusa ho thibela nts'etsopele ea boemo bona ba methapo le mafu a fapaneng a methapo ea pelo.
Nakong ea phekolo ea lithethefatsi, nako ea prothrombin e eketseha, matla a ts'ebetso ea tlhahiso ea prothrombin ka har'a sebete a fokotseha. Ho kenyelletsa moo, ho na le ho fokotseha ho hoholo ha lintho tse kopanetsoeng (ho itšetleha ka Vitamin K-feela).
Ha u nka thrombital le cardiomagnyl, bokhoni ba liplatelete tse khomarelang maboteng a methapo ea mali boa fokotseha.
Ho na le li-contraindication tse 'maloa tse ka sehloohong, moo lithethefatsi li ka bakang kotsi:
- hemorrhage
- dysfunction
- ho mpefala ha ulcer ea ka mpeng,
- ho ba teng ha asthma ea bronchial nakong ea kalafo le NSAIDs,
- khatello e matla ea renal,
- ho ima nakong ea pele le ea boraro
- lebone
- hypersensitivity ho likarolo tsa meriana,
- lilemo tse 18
- ho hloleha ha rems
- Pheko ea methotrexate.
Lithethefatsi li lokela ho nkuoa ka hloko e kholo ka lebaka la kotsi e ka hlahang maemong a latelang:
- gout
- mosebetsi o eketsehileng oa li-enzyme tsa sebete,
- hyperuricemia
- nalane ea liso tsa ka mpeng le ho tsoa mali,
- asthma ea lefu la bronchial,
- polyposis ka nko,
- allergy
- moimana oa li-trimesters tse 2.
Maemong a mang, ho nka lipilisi ho ka ba kotsi, ka hona, ha ho khetholloa li-contraindication, ha lia lokela ho hlokomolohuoa. Haeba ho na le li-contraindication tse amanang, qeto e emelang ho amoheloa e lokela ho etsoa ke ngaka.
Leha taba ea hore lithethefatsi li rua molemo ho tsoa ho mafu a pelo le methapo ea mali, ntlafatsa ts'ebetso ea mesifa ea pelo, haeba litekanyetso li fetisitsoe, li ka baka kotsi ho bophelo bo botle. Botebo ba bongoana bo hlalositsoe e le:
- Bohareng. Ho na le ho nyekeloa le pelo le ho hlatsa, tinnitus, mafu a hematopoietic system - ho eketseha hoa mali, khaello ea mali. Ho utloa ho mpefala, pherekano le ho tsekela ho etsahala. Mokuli o hlatsoa ka mpeng mme ho fanoa ka tekanyo e lekaneng ea khabone e tlatsitsoeng. Phekolo e itšetleha ka setšoantšo sa kliniki khahlano le overdose.
- E boima. Mofoka, komisi, phefumoloho le pelo le ho se lekane hantle, hypoglycemia e tsebahala. Phekolo e etsoa sepetlele. Mokuli o bontšoa kalafo e matla, e kenyeletsang ho hlahisoa ha tharollo e khethehileng ea alkaline, ho tsamaisa diuresis le gastric lavage, hemodialysis.
Tabeng ea bongoana bo bongata ba mokokotlo, ho nyekeloa le pelo le ho hlatsa, tinnitus li bonoa.
Lithethefatsi tsena li ntlafatsa phello ea meriana e itseng, ha feela li sebelisoa hammoho:
- Methotrexate Phokotso ea lipholiso tse fokotsehileng, tšenyo ea litlamo le liprotheine.
- Heparin le anticoagulants tse sa tobang. Liplatelete li fetola tšebetso ea tsona. Li-anticoagulants li qobelloa ho tsoa litlamong tsa tsona le liprotheine.
- Li-antiaggregant le hypoglycemic agents - ticlopidine.
- Litokisetso tse nang le ethanol.
- Lithethefatsi tsa insulin le hypoglycemic.
- Digoxin. Ho na le ho fokotseha ha cheso e tsoang mpeng.
- Valproic acid. Ho e qobella ho tsoa litlamong tsa eona le liprotheine.
Ka lehlakoreng le leng, meriana e hatella phello ea:
- li-uricosuric agents
- antacid le colestyramine.
Melemo ea lithethefatsi tsena e ea fokotsoa ha e nkuoa le Ibuprofen.
Ho sebelisana le lithethefatsi
Ka ts'ebeliso e kopaneng ea acetylsalicylic acid e ntlafatsa ts'ebetso ea lithethefatsi / lintho tse latelang ka lebaka la nts'etsopele ea litlamorao tse latelang:
- digoxin - makhopo a eona a hlaba a fokotsehile,
- methotrexate - tumello e fokotsitsoeng ea renal, 'me ntho ena ha e khone ho buisana le liprotheine, motsoako ona o lebisa hoketseho ea liphihlelo tse mpe tse tsoang liphatsong tsa mali tse bopang mali,
- antidiabetesic molomo o tsoang ho (sulfonylurea derivatives) le insulin - acetylsalicylic acid e ho litekanyetso tse phahameng e bonts'a phello ea hypoglycemic, litlamorao tsa sulfonylurea li hulanngoa puisanong le liprotheine tsa plasma tsa mali,
- heparin le anticoagulants e sa tobang - ts'ebetso ea liplatelete ha e sebetse, li-anticoagulants tse sa tobang li qheleloa thoko ho buisana le liprotheine tsa plasma,
- valproic acid - sena se qhelellehileng puisanong le liprotheine tsa plasma,
- analcics ea narcotic, li-NSAID tse ling, thrombolytic, antiplatelet le anticoagulant agents (ticlopidine) - tlhokomeliso e lokela ho sebelisoa ka mokhoa ona.
Ha acetylsalicylic acid e kopantsoe le lithethefatsi / lintho tse ling, litlamorao tse latelang li ka bonoa:
- Barbiturates le letsoai la lithium - mahlaseli a plasma ea li-agents tsena a eketseha,
- ibuprofen - phello ea pelo le acetylsalicylic acid e fokotseha ha e sebelisoa ho litekanyetso ho fihlela ho 300 mg ka lebaka la bofokoli ba phello ea antiplatelet, moo ho nang le kotsi e eketsehileng ea lefu la pelo, motsoako ona ha o khothalletsoe,
- anticoagulants, thrombolytics, antiplatelet agents - menyetla ea ho tsoa mali e eketsoa haholo,
- GCS, lithethefatsi tse nang le ethanol le ethanol - litlamorao tse mpe ho mucosa ea ka mpeng li eketseha, 'me menyetla ea ho tsoa mali ka mpeng e eketseha,
- systemic corticosteroids - ho felisoa ha li-salicylates ho matlafatsoa, 'me phello ea tsona ea fokola, kamora ho hlakoloa ha ts'ebeliso ea li-corticosteroids tsa systemic, kotsi ea ho eketseha ha li-salicylates li eketseha.
- ethanol - matla a chefo a ntho ena ho tsamaiso ea methapo e bohareng a eketseha,
- colestyramine, li-antacid - monko oa acetylsalicylic acid o fokotsehile,
- litokisetso tsa uricosuric (probenidal, benzbromaron) - phello ea bona e fokola ka lebaka la tlholisano ea khatello ea methapo ea methapo ea methapo ka uric acid,
- angiotensin-converting enzyme inhibitors - ho fokotseha ho itšetlehileng ka tekanyetso ea sekhahla sa ho se lekantsoe ha glomerular ho bonoa ka lebaka la thibelo ea li-prostaglandins, ho bonts'a phello ea vasodilating mme, ka lebaka leo, ho fokotseha hoa phello e matlafatsang.
- diuretics (hammoho le litekanyetso tse phahameng tsa asiti ea acetylsalicylic) - ho fokotseha ha sekhahla sa ho fifala hoa moea ka lebaka la ho fokotseha hoa tlhahiso ea li-prostaglandins lipelong hoa khoneha.
Litšoantšiso tsa Trombital ke: Cardiomagnyl, Trombital Forte, ThromboMag, Phasostabil.
Tlhahlobo
Litlhahlobo mabapi le Trombital li ntle haholo. Bakuli ba hlokomela katleho ea moemeli oa antiplatelet ha e sebelisoa ho thibela mafu a pelo, litlhaselo tse pheta-phetoang tsa myocardial infarction le thromboembolism kamora ts'ebetso ea ts'ebetso likepeng, hammoho le thibelo ea litlhaselo tsa angina. Ho latela maikutlo, kamora kalafo le moriana ho na le sephetho se phehellang. Hape, bakuli ba hlokomela boitsebiso bo felletseng ba sehlahisoa sena le Cardiomagnyl ea kantle ho naha, empa theko ea lithethefatsi tsa Russia e tlase haholo ho feta molekane oa eona, e leng bohlokoa ho bakuli nakong ea kalafo ea nako e telele.
Likotsi tsa lithethefatsi li kenyelletsa lenane le leholo la li-contraindication le karabelo e mpe. Ho fokotsa litlamorao tse sa rateheng tsa tšilo ea lijo, bakuli ba bangata ba khothaletsa ho nka lijo tse ngata ka mor'a lijo.
Tšobotsi ea Trombital
Moetsi oa lihlahisoa - Pharmstandard (Russia). Mofuta oa tokollo ea lithethefatsi ke matlapa a koahetsoeng ka filimi. Ena ke sesebelisoa sa likarolo tse peli. Lithako tse sebetsang ka sebopeho sa eona: acetylsalicylic acid (75-150 mg), magnesium hydroxide (15.20 kapa 30.39 mg). Khokahano ea likarolo tsena e bontsitsoe bakeng sa Letlapa le le leng. Melemo ea sehlooho ea lithethefatsi:
- khahlano
- antithrombotic.
Ho fumana hore na ke eng e betere, thrombital kapa cardiomagnyl, ho a hlokahala ho lekola boemo ba ts'ebetso ea lithethefatsi.
Tšusumetso e ntle e fanoa ka lebaka la phello ea liplatelete. Setlhare se thibela tlholeho ea thromboxane A2, e fokotsang bokhoni ba liplatelete ho khomarela marako a methapo ea mali. Ka nako e ts'oanang, ho na le ho theoha butle-butle ts'ebetsong ea ho tlama lisele tsena tsa mali ho e mong, ho etsoa ha methapo ea mali ho thibetsoe. Thepa ea antithrombotic e bonahatsoa nakong ea matsatsi a 7. Ho fihlela sephetho sena, ho lekane ho nka tekanyetso e le 'ngoe ea moriana.
Bala haholoanyane ka e 'ngoe le e' ngoe ea lithethefatsi lihloohong:
Letlotlo le leng la acetylsalicylic acid ke bokhoni ba ho ba le phello e ntle tsamaisong ea pelo le pelo. Ka kalafo ka ntho ena, ho na le phokotso ea menyetla ea lefu ka infraate ea myocardial. Setlhare se thusa ho thibela nts'etsopele ea boemo bona ba methapo le mafu a fapaneng a methapo ea pelo.
Ka kalafo ea "thrombital", nako ea prothrombin ea eketseha, matla a ts'ebetso ea tlhahiso ea prothrombin ka har'a sebete a fokotseha. Ho kenyelletsa moo, ho na le ho fokotseha ho hoholo ha lintho tse kopanetsoeng (ho itšetleha ka Vitamin K-feela).
Thepa ea antithrombotic e bonahatsoa nakong ea matsatsi a 7. Ho fihlela sephetho sena, ho lekane ho nka tekanyetso e le 'ngoe ea moriana.
Pheko ea "thrombital" e lokela ho etsoa ka hloko haeba li-anticoagulants tse ling li laetsoe ka nako e le 'ngoe. Kotsi ea mathata a mangata ea eketseha, ho tsoa mali ho ka buleha.
Ntle le moo, thepa e meng ea acetylsalicylic acid e boetse e bonahatsoa: anti-inflammatory, antipyretic, analgesic. Ka lebaka lena, thrombital e ka sebelisoa ho fokotsa mocheso o phahameng oa 'mele, bakeng sa bohloko ba li-etiologies tse fapaneng, khahlano le semelo sa ho ruruha ha methapo ea methapo. Thepa e 'ngoe ea lithethefatsi ke bokhoni ba ho potlakisa tlhahiso ea li-uric acid.
Likotsi tsa sethethefatsi li kenyelletsa phello e mpe ho li-membrane tsa mucous tsa litho tsa mokokotlo. Ho fokotsa phello ea acetylsalicylic acid le ho thibela nts'etsopele ea mathata, karolo e 'ngoe e ile ea kenngoa ka sebopeho - magnesium hydroxide. Matšoao a sebelisang thrombital:
- thibelo ea lefu la pelo le methapo ea pelo le thibelo ea ho nyekeloa ke pelo,
- Thibelo ea mali,
- thibelo ea thromboembolism ka mor'a ho buuoa likepeng,
- kotsi e fokotsehileng ea ho nchafatsoa hoa inflation ea myocardial,
- angina pectoris.
Ketso ea Cardiomagnyl
Cardiomagnyl e etsoa ke Takeda GmbH (Jeremane).
Foromo ea litekanyetso: matlapa a tlotsitsoeng ka ente.
Lithako tse sebetsang: acetylsalicylic acid - 75/150 mg, magnesium hydroxide - 15.2 / 30.39 mg.
Ba hlahisang: cellcose ea microcrystalline, starch ea poone, starch ea litapole, magnesium stearate.
Shell: methylhydroxyethyl cellulose, propylene glycol, talc.
Phapang ke efe le ho tšoana hofe lipakeng tsa Thrombital le Cardiomagnyl?
Lithethefatsi li tšoana ka litekanyetso tsa ntho e sebetsang - acetylsalicylic acid (ASA), hammoho le antacid - magnesium hydroxide. Mohato oa ts'ebetso ea lithethefatsi tsena o ipapisitse le mofuta oa litlamorao tsa litekanyetso tsa litlamorao tsa ASA 'meleng.
Ka litekanyetso tse nyane, asiti ea acetylsalicylic e bonts'a thepa ea antiplatelet, i.e. e khona ho theola mali.
ASA ka litekanyetso tsa 30-300 mg / ka letsatsi. e thibela ka mokhoa o sa fetoheng enzymes cycloo oxygenase (COX), e kenyang karolo ho theheng ha thromboxane A2. Thepa ena ea ASA e sebelisetsoa ho thibela mafu a pelo le amanang le keketseho ea ponahalo ea mali: thromboembolism, stroke le ischemic le infarction ea myocardial.
Har'a litla-morao tsa ASA, ts'okelo e kholo ke kotsi e eketsehang ea khoholeho ea mahlo le liso tsa lona marakong a mpa le duodenum. Tšusumetso ena e sa rateheng e amahanngoa le ho thibeloa ha thepa ea cytoprotective ea lisele tsa methapo ea methapo ha e koala enjene ea COX, e sa ameheng feela kenyelletsong ea thromboxane A2, empa hape le sebopeho sa prostaglandins (PG). Thibelo ea motsoako oa GHG e boleloa haholo ha ho nooa tekanyetso e kholo ea ASA (4-6 g), empa cytoprotection e senyehileng ea lithane e bonahala ha u sebelisa litekanyetso tse nyane.
Ho sireletsa marako a pampitšana ea ka mpeng, matlapa a Trombital le Cardiomagnyl a koahetsoe ka kobo ea lifilimi ea enteric, sebopeho sa eona se nang le liphapang tse sa amang thepa ea bona ea ts'ireletso.
Likarolo tse sebetsang tsa litlhare ha li na phapang ea sebopeho kapa litekanyetso, ka hona, matšoao a ho nka meriana ena a tšoana hantle:
- Prophylaxis ea mantlha ea thrombosis le ho nyekeloa ke pelo haholo ha ho e-na le lisosa tsa kotsi (lefu la tsoekere, khatello ea maikutlo, khatello ea maikutlo, botena, ho tsuba, lilemo tse fetang 50).
- Thibelo ea sekhahla sa myocardial infarction le thrombosis.
- Thibelo ea thromboembolism ka mor'a ho etsoa opereishene ea methapo.
- Angina pectoris:
Lits'ebetso tsa ho nka meriana ena ke:
- mamello ho li-NSAIDs, haholo-holo ASA,
- ulcer peptic in the acute phase kapa anamnesis,
- tloaelo ea ho tsoa mali ka mpeng ea tšilo ea lijo,
- asthma ea lefu la bronchial,
- polyposis ea mucosa ea ka mpeng,
- hemophilia
- hemorrhagic diathesis,
- hypoprothrombinemia,
- strandra aortic aneurysm.
Ke eng e theko e tlase?
Bakeng sa papiso, tafole e bonts'a litheko tsa lithethefatsi tsena tsa mefuta e fapaneng ea tokollo:
Lebitso la lithethefatsi | Tekanyetso (ASA + magnesium hydroxide), mg | Ho paka | Theko, rub. |
Cardiomagnyl | 75+15,2 | 30 | 121 |
100 | 207 | ||
150+30,39 | 30 | 198 | |
100 | 350 | ||
Trombital | 75+15,2 | 30 | 93 |
100 | 157 | ||
Trombital Forte | 150+30,39 | 30 | 121 |
100 | 243 |
Domestic Thrombital ke ente e theko e tlaase ea antiplatelet ho feta molekane oa eona oa Jeremane.
Na ho na le monyetla oa ho khutlisetsa bophelo ba "thrombital" ka "cardiomagnyl"?
Lithethefatsi tsena li ka fetoloa nakong ea kalafo ea thibelo, hobane ha li na likarohano ka har'a likarolo tse sebetsang. Matšoao a ts'ebeliso le a contraindication a tšoana.
Krasko A. V., setsebi sa pelo, Tatishchevo: "Ka tsamaiso e ts'oanang ea litokisetso tse nang le acetylsalicylic acid, ts'ebetso ea bona ea hepatotooticity e matlafalitsoe. Lithethefatsi tsena li lokela ho fanoa ke ngaka, 'me thupelo ea thibelo e lokela ho etsoa ka tlhatlhobo ea bongaka (litlhahlobo, OAK)."
Marinov M. Yu., Therapist, Verkhoyansk: "Ho fumaneha ha meriana ena, ka lehlakoreng le leng, ho molemo bakeng sa mokuli, empa ka lehlakoreng le leng, ho eketsa kotsi ea liphoso tsa ho itlhalosa. Lithethefatsi li boetse li sebelisetsoa ho fokotsa boemo ba bakuli ba nang le methapo ea varicose kapa koluoa ea mokokotlo. "Ho phethoa ha thupelo ea prophylactic e lokela ho etsahala butle le ka tlase ho taolo ea ngaka. Ka ho lahla lithethefatsi ka matla, ho na le monyetla oa ho eketseha ha mali.
Alina, ea lilemo li 24, Moscow: "Lithethefatsi tsena ka bobeli li ka nkela matlapa a bonolo a Acetylsalicylic acid - sesebelisoa se theko e tlase, empa ho le thata ho se sebelisa ho nyenyefatsa mali.
Olga, ea lilemo li 57, Barnaul: "Ke ikhethetse Cardiomagnyl qalong ea prophylaxis. Empa ka e nkela Trombital. Ha ke utloe phapang efe kapa efe. Ha ke bone litla-morao tse ngata. Ho na le menyenyetsi e mengata ea lithethefatsi tsena litlolong."
Phapang ke efe pakeng tsa Thrombital le Cardiomagnyl
Thrombital e hlahisoa ka matlapa a koahetsoeng, a fokotsang tekanyo ea litlamorao tse mpe ka mpeng. Cardiomagnyl e fumaneha matlapeng a sa koaeloang, ka hona, acid e acetylsalicylic e sebetsa ka mokhoa o hlekefetsang ho mucosa ea ka mpeng.
Phapang ea litšenyehelo e nyane. Phasele ea Trombital (matlapa a 30) e bitsa li-ruble tse ka bang 115, Cardiomagnyl - li-ruble tse 140.
Sebopeho le litekanyetso tsa lithethefatsi li tšoana, ka hona li na le lipontšo le li-contraindication. Thrombital e khethoa haholoanyane kalafong ea maloetse a pelo ka lebaka la ho koaloa ha filimi matlapeng.
Litlhahlobo tsa lingaka mabapi le Trombital le Cardiomagnyl
Dmitry, ngaka e buoang masapo, Moscow
Thrombital e laeloa khafetsa ho bakuli ba nang le methapo ea methapo. Tekanyetso - 75 mg hang hang ka letsatsi bakeng sa lijo tsa motšehare ka mor'a lijo. Sethethefatsi se seholo le se theko e tlaase. Moriana o nepahetseng o sebelisang opereishene ea methapo. Bakuli bohle ba khotsofetse ke theko le boleng ba lithethefatsi.
Vladimir, ngaka ea methapo ea pelo, St.
Cardiomagnyl e na le litekanyetso tsa 75 mg, e leng tekanyo e tlase e sebetsang ho fokotsa kotsi ea infraction ea myocardial le stroke. E theola dikahare tsa ASA ho lithethefatsi, e fokotsa kotsi ea ho tsoa mali. Kahoo 75 mg e molemo ntlheng ena ho feta 100 mg. Maemong ana, Cardiomagnyl e ka ntlafatsa kholo ea kholo ho bakuli.
Igor, phlebologist, Vladivostok
Lits'enyehelo tse tlase tsa lithethefatsi, katleho e phahameng mabapi le thibelo ea mafu a pelo le mathata a tsona, liperesente tse fokolang tsa litlamorao tse mpe, tekanyetso e le 'ngoe nakong ea letsatsi. Cardiomagnyl ke moriana oa bohlokoahali ts'ebetsong ea methapo ea methapo, e fuoang bakuli bohle ba 50+ ba nang le methapo ea methapo ea methapo ho thibela stroke, ho nyekeloa ke pelo le thrombosis.
Cardiomagnyl e fumaneha matlapeng a sa koaeloang, ka hona, acid e acetylsalicylic e sebetsa ka mokhoa o hlekefetsang ho mucosa ea ka mpeng.
Tlhahlobo ea Mamello
Marta, ea lilemo li 34, Yaroslavl
O nkile Trombital Forte (ka tekanyo e phahameng ea lintho tse sebetsang). Liphello tse mpe li ile tsa hlaha: ho tšoenyeha ha boroko, ho opeloa ke hlooho, ho tsekela, ho nyekeloa. Ke fetohetse Trombital ka lethal dose le tlase la likarolo tsa sehlooho. O ile a fumana kalafo ntle le mathata.
Alena, ea lilemo li 36, Nizhny Novgorod
Ke se ke qetile lilemo tse fetang tse tharo ke noele Cardiomagnyl. Ha ho na litla-morao tse tsoang litlhareng tsena. Botoro e nka likhoeli tse 3. Ke nwa pilisi e le 1 ka letsatsi, ke reka pakete ea matlapa a 100, ka lethal dose ea 75 mg. E lokela ho nooa khafetsa, hobane ke na le hemodialysis, ho na le fistula, haeba u sa e noe, ho ka ba le makhopho a mali. Joale ho ke ke ha khonahala ho etsa mokhoa oa hemodialysis. Feela ha o beha catheter, empa e ka boela ea koaloa. Ka hona, ke e noella khafetsa, ea thusa, sethethefatsi se setle.
Victoria, ea lilemo li 32, Volgograd
Setlhare sena se ile sa nkuoa nakong ea kemaro, hobane placenta e ne e sa fuoe mali hantle 'me tsoalo pele ho nako e ka qala, ka tekanyo e behiloeng ea 75 mg hang ka letsatsi kamora lijo tsa mantsiboea tse peli. Nakong ena, ho ne ho se na mathata ka mpeng, ke li-noseble tse neng li ata khafetsa. Empa kaha lintlafatso li ne li bonahala ho li-ultrasound, joale likutu tse ka nkong ka lebaka la ngoana li ka mamelloa.
Sebopeho sa Thrombital le Cardiomagnyl
Karolo e sebetsang ea Cardiomagnyl ke acetylsalicylic acid. Ha e kenella maling, e thibela tlhahiso ea "thromboxane" (liplatelete li khomarelana tlasa ts'usumetso ea enzyme ena, e hlahisang thrombosis).
Sesebelisoa se seng tlatsetsong ke magnesium hydroxide. Ke antacid (ntho e theolang acidity ea mpeng).
Ka ho kopana ha acetylsalicylic acid e nang le magnesium hydroxide, ha e bonts'a thepa ea eona e kotsi ebile ha e senye membrane ea mucous. Monyetla oa bohlokoa ke ho haella ha tšebelisano ea likarolo, ka lebaka leo li kenang maling ka bolokolohi.
Sebopeho sa Trombital se kenyeletsa likarolo tse tšoanang. Kameho ea tšebeliso e tsoela pele beke kamora 'tsamaiso. Bohlokoa! Lintho tse sebetsang li fokotsa kotsi ea tsoelo-pele ea myocardial infaration. Li fana ka katleho le ts'ebetso ea thibelo ea stroke. Ka tekanyo e phahameng, ba na le litlamorao tsa anti-inflammatory le analgesic.
Ho bapisa: ho tšoana le ho se tšoane
Lithethefatsi tse boletsoeng li na le tšebetso e pharalletseng. Matšoao a ts'ebeliso ea ona ke a latelang:
- Thibelo le kalafo ea thrombosis.
- Pheko ea thromboembolism ka mor'a ho buuoa ka methapo.
- Boteng ba angina e sa tsitsang.
U tlameha ho hopola! Haeba e 'ngoe ea litlhare e sa lokele mokuli, ha ho ratehe ho e khutlisa ka analog. Ho seng joalo, hypersensitivity e tla hlaha.
Contraindication bakeng sa ts'ebeliso e tjena:
- Ho tsoa mali le ho hoama ho tlase.
- Nalane ea asthma.
- Ho hloleha ho ho phekola ha liphoko.
Hlokomela! Ha hoa lumelloa ho sebelisa meriana e joalo ho bakuli ba ka tlase ho lilemo tse 18. Ho bohlokoa ho tlohela ts'ebeliso ea bona ho "trimester" ea pele le ea boraro ea bokhachane, hobane joale ho etsoa hoa litho tsa mpa tsa kamoso ho etsahetse (ho emisa ts'ebetso).
Basali ba nang le 'mala ba ka sebelisa lipilisi tsena ka nako e khuts'oane, hobane matsoai a kenella ka lebeseng.
Phapang e thathamisitsoe ka har'a tafole:
Trombital | Cardiomagnil | |
Fomu ea tokollo | Matlapa a koahetsoeng ka filimi | Ha ho sheath filimi |
Palo ea litafole ka pakete e ngoe le e ngoe | 100 | 30 |
Tekanyetso e khothalletsoang ke ngaka e lokela ho bonoa e le ho qoba ho sebelisa joala bo bongata, bo tsamaeang le ho hlatsa, tinnitus. Ha matšoao ana a hlaha, o hloka ho hlatsoa mpa ea hau.
Ke eng e betere Cardiomagnyl kapa Thrombital
Ha u khetha sehlahisoa, u lokela ho nahana ka tlhoko ea ho sila pele u e sebelisa. Haeba ho na le tlhoko e joalo, ho molemo ho khetha Cardiomagnil, hobane e na le likotsi.
Meriana ena ka bobeli ha e na tsoekere. Kahoo li ka jeoa ke bakuli ba nang le lefu la tsoekere. Bohlokoa! Lithako tse kenyellelitsoeng sebopeng sa tsona li matlafatsa ketso ea Heparin le Digoxin. Ha ho kgothaletswe ho kopanya meriana le li-anticoagulants. Ho seng joalo, ho tsoa mali ho ka hlaha.
Netefatsa katleho ea karabo e tsoang ho basebelisi 'me lingaka li tla thusa.
Ho tsoa ho angina pectoris, ngaka e ile ea eletsa Cardiomagnil. Ke ne ke thabetse hore ha e felise matšoao a lefu lena ka potlako, empa hape ha e na tsoekere (ke na le nalane ea lefu la tsoekere).
Phapano ke efe lipakeng tsa molaoli oa tšireletso le mofuputsi: mosebetsi ke eng, phapang ke efe. Bona tlhahisoleseling mona.
Ho tloha ho thrombosis, ngaka e ngotse thrombital. Melemo ea eona ea mantlha ke theko e tlase ebile e sebetsa hantle kalafong le ho thibela mafu a pelo.
Bakeng sa kalafo ea mafu a pelo, ke fana ka taelo ea Trombital kapa Cardiomagnil bakeng sa bakuli. Ho ba teng ha li-contraindication bakeng sa ts'ebeliso ho felisoa ka theko e tlase le ts'ebetso.
Bona litaelo tsa video bakeng sa "Cardiomagnyl":
Phapang pakeng tsa Trombital le Cardiomagnyl
Ha u khetha litokisetso tsa Trombital kapa Cardiomagnyl, u lokela ho qala ho tloaela litšobotsi tsa bona, litšobotsi tse akaretsang le phapang. Maemong ana, khetho ea meriana e lokela ho etsoa ke ngaka e eang.
Ha u khetha litokisetso tsa Trombital kapa Cardiomagnyl, ho hlokahala hore u ithute likarolo tsa bona, litšobotsi le liphapang.
Phapano le ho tšoana ha Trombital le Cardiomagnyl ke eng?
Meriana e na le sebopeho se tšoanang le litekanyetso, ka hona li baka litlamorao tse tšoanang. Matšoao le lithibelo mabapi le tšebeliso ea lithethefatsi le tsona lia tšoana.
Trombital ea lithethefatsi e fumaneha ka sebopeho sa letlapa. Tabeng ena, matlapa a kopantsoe le khetla e sirelletsang, ka lebaka leo menyetla ea phello e mpe ho metso ea mucous ea litho tsa mokokotlo e fokotsehile.
Letlapa la litlhare tsa Cardiomagnyl ha le na membrane ea filimi, ka hona, acetylsalicylic acid, khahlano le semelo sa ts'ebeliso ea eona, e na le litlamorao tse matla tsamaisong ea tšilo ea lijo.
Maikutlo a lingaka
Igor (phlebologist), ea lilemo li 38, Syktyvkar
Lithethefatsi tsena li fokolisa mali ka katleho li thibela nts'etsopele ea methapo e mengata ea pelo le methapo. Hangata, ke fana ka litlatse tsa katleho, hobane lipilisi tsena li entsoe ka koae e khethehileng, e etsang hore kalafo ea bona e bolokehe. Cardiomagnyl e theko e tlaase. Leha ho le joalo, ke ne nke ke ka eletsa ho boloka bophelo ba ka. Ho feta moo, phapang ea litheko e nyane.
Dmitry (ngaka e buoang), ea lilemo li 40, Vladimir
Lithethefatsi ka bobeli li na le katleho e phahameng. Ba na le phapang e le 'ngoe feela - boteng ba membrane ea filimi ho Trombital ea lithethefatsi. Cardiomagnyl ha e na eona, ka hona e lokela ho nkoa ka tlhokomelo e khethehileng mme e le tlasa taolo ea ngaka. Lipheko tsena li mamelloa hantle ke bakuli ba lefu la tsoekere le bakuli ba tsofetseng. Boitšoaro bo bobe ha bo hlahe haeba u latela litaelo tsa bongaka le litlhoko tsa litaelo.
Matšoao le contraindication bakeng sa ts'ebeliso
Morero oa kalafo ka moriana ona ke ho ntlafatsa ts'ebetso ea litho tsa tsamaiso ea methapo ea pelo, ho thibela ho thehwa ha methapo ea mali.
Moriana o fuoa meriana bakeng sa ho qoba litlamorao tse ka bang teng ho bakuli ba sehlopheng sa batho ba kotsing (ba nang le botenya, lefu la tsoekere, khatello ea methapo ea mali le lihlopha tsa batho ba tsofetseng).
Setlhare se fuoe thrombosis
Ntle le kalafo e ka sehloohong, sethethefatsi se ka laeloa kamora ho buuoa (ho kenyeletsa le coronary artery bypass grafting). Ts'ebeliso ea nako ea lithethefatsi ka nako ea kalafo e thusa ho fokotsa phokotseho e kholo ea monyetla oa hore ho be le thrombosis.
Tsamaiso ea li-trombital e bontšoa ho bakuli:
- ka angina e sa tsitsang,
- Ho thibela sebopeho sa thrombosis kamora ts'ebetso,
- ka nts'etsopele ea mantlha ea lefu la pelo le methapo ea methapo,
- molemong oa ho thibela ho thetsoa hoa myocardial infarction,
- khahlanong le semelo sa ho hloleha ha pelo ketsahalo e mpe,
- ho thibela ho thehwa ha makatse a madi ka hara lijana.
Sesebelisoa se na le lithibelo tse itseng mabapi le tšebeliso. Ha ho kgothaletswe ho sebelisa matlapa bakeng sa batho ba nang le tloaelo ea ho hemorrhage (khahlano le semelo sa thrombocytopenia, khaello e matla ea vithamine K, hemorrhagic diathesis).
Ho thibetsoe ka thata ho nka bakuli ba nang le mamello ea li-aspirin, lithethefatsi tse seng khahlanong le ts'oaetso tsa motsoako, hammoho le karolo efe kapa efe ea lithethefatsi. Sesebelisoa sena ha se sebelisoe ho bana, ha se loketse bana.
Ntle le moo, sesebelisoa se ke ke sa nkuoa boteng ba maemo a joalo.
- tahlehelo ea mali
- phallo ea mali ka mpeng kapa mala.
- lefu la pelo 3 le FC, e phalla ka sebopeho se sa foleng,
- ho hloleha ho matla ha hepatic le renal,
- Asthma ea bronchial e tsamaeang le ho se bone pono ea acetylsalicylic acid,
- mafu a etiology ea ho ruruha litho tsa tsamaiso ea tšilo ea lijo e sa sebetseng hantle,
- basali nakong ea ho beleha le nakong ea ho anyesa.
Litaelo tsa ho sebelisoa
Ho amohela ho lokela ho etsoa ka mokhoa oa molomo hang ka letsatsi. Haeba o na le bothata ba ho koenya moriana oo kaofela, o ka o hlafuna kapa oa o sefa ka pele o sebelisoa.
Tekanyetso ea moriana e bakoa ke sepheo seo e laetsoeng le ho hlalosoa ka sona tafoleng e ka tlase:
Boloetse | Tekanyetso |
---|---|
Phekolo ea mathata a pelo le methapo ea mali, ho kenyelletsa le thrombophlebitis le ho hloleha ha pelo haholo, ka mabaka a teng a kotsi, e le mehato ea mantlha ea thibelo. | Nakong ea letsatsi la pele, litekanyetso tsa letsatsi le letsatsi ke matlapa a mabeli, joale o hloka ho noa karolo e le 'ngoe ka letsatsi. |
Bakeng sa ho thibela nts'etsopele ea thrombophlebitis kamora ho buuoa ho etsoang methapong ea mali, infarction ea sekhahla sa myocardial le maro a mali tsamaisong ea mali. | Likotoana tse 1-2 ho pholletsa le letsatsi |
Angina e sa sebetseng | Litekanyetso tsa letsatsi le letsatsi ke likotoana tse 1-2 (e le ho fihlela monko o potlakileng, letlapa la pele la lithethefatsi le tlameha ho hlafuna). |
Bohlokoa! Pheko e akaretsang e kenyelletsa tšebeliso ea nako e telele, palo ea nako le kalafo e lokela ho khethoa ke ngaka e eang.
Hoa hlokahala ho sebelisa moriana, ho shebella ka hloko litlhahiso tsa bongaka.
Thrombital le Cardiomagnyl: phapang ke efe
Ho ea ka ntho ea teng, litekanyetso tsa lisebelisoa tse sebetsang, matšoao le li-contraindication bakeng sa tšebeliso, thrombital le cardiomagnyl ke li-analogues. Empa ka lebaka la hore matlapa a Trombital a na le membrane ea filimi e sirelletsang, a khethiloe ha a bapisoa le Cardiomagnyl kalafong ea mafu a litho tsa 'mele tsamaisong ea pelo le methapo, hobane li ama ts'ebetso ea tšilo ea lijo ka mokhoa o tlase.
Sehlooho | Theko | |
---|---|---|
Thrombo | ho tloha ho 45,00 rub. ho fihlela ho 4230.00 rub. | pata ho bona litheko ka botlalo |
Trombital | ho tloha 76,00 rub. ho fihlela ho 228.00 rub. | pata ho bona litheko ka botlalo |
Trombital | ho tloha 76,00 rub. ho fihlela ho 228.00 rub. | pata ho bona litheko ka botlalo |
Cardiomagnyl | ho tloha 119,00 rub. ho fihlela ho 399.00 rub. | pata ho bona litheko ka botlalo |
Litheko le maemo a matsatsi a phomolo libakeng tsa meriana
O ka reka "mele o mong le o mong" ka har'a litlama tsohle ntle le lengolo le tsoang ho ngaka. Litsenyehelo tsa moriana li bakoa ke litekanyetso le palo ea matlapa a sephutheloaneng, 'me ke li-ruble tse ka bang 92-157.
palo ka pakete e ngoe le e ngoe - 30 likhomphutha | |||
---|---|---|---|
Tate | Lebitso | Theko | Moetsi |
Evropharm RU | thrombital 75 mg 30 matlapa | 76,00 rub | OJSC Pharmstandard-Lexredst RU |
Evropharm RU | thrombital forte 150 mg 30 tab. | 120.00 r | Horton-Leksredstva |
palo ka pakete e ngoe le e ngoe - 100 likhomphutha | |||
Tate | Lebitso | Theko | Moetsi |
Lenane la lipilisi | Matlapa a Thrombital 75mg + 15.2mg No. 100 | 158,00 rub | RUSSIA |
Evropharm RU | thrombital 75 mg 100 tab. | 165,00 rub. | Horton-Leksredstva |
Evropharm RU | thrombital forte 150 mg matlapa a 100 | 210,00 rub | OJSC Pharmstandard-Lexredst RU |
Lenane la lipilisi | Matlapa a Trombital Forte 150mg + 30.39mg No. 100 | 228,00 rub | RUSSIA |
Katleho ea Trombital kalafong ea mathata a pelo le merero ea thibelo e bonahatsoa ke litlhahlobo tse ntle tse ngata tsa batho ba sebelisitseng moriana ona. Sesebelisoa se thusa ho fokotsa kotsi ea thrombosis, ho ntlafatsa ts'ebetso ea methapo ea methapo ea pelo le pelo, ho thibela nts'etsopele ea myocardial infarction ho batho ba kotsing.