Litaelo tsa 600 tsa Berlition bakeng sa li-analogues tsa litekanyetso

Berlition 600: litaelo tsa tšebeliso le litlhahlobo

Lebitso la Latin: Berlithion 600

Khoutu ea ATX: A16AX01

Motsoako o sebetsang: Thioctic acid (Thioctic acid)

Moetsi: Jenahexal Pharma, Pharma ESOHLE Jena GmbH, Haupt Pharma Wolfratshausen (Jeremane)

Ho nchafatsa litlhaloso le foto: 10/22/2018

Berlition 600 ke boitokisetso ba metabolic ba ts'ebetso ea antioxidant le neurotrophic e laolang metabolism.

Sokolla foromo le sebopeho

Mofuta oa litekanyetso tsa Berlition 600 ke mohopolo bakeng sa ho hlophisoa ha tharollo ea motsoako: mokelikeli o hlakileng, botala bo bosehla ho 24 ml ka li-ampoules tsa khalase tse lefifi (25 ml) ka mohala oa ho phumula (label e tšoeu) le metsero e putsoa-e putsoa ka botala. Li-pcs tse 5. ka pokellong ea polasetiki, ka mokotleng oa karete e le 'ngoe.

1 ampoule e na le:

• ntho e sebetsang: thioctic acid - 0,6 g,
• likarolo tse thusang: ethylenediamine, metsi bakeng sa ente.

Mofumahali

Motsoako o sebetsang oa Berlition 600 - α-lipoic (thioctic) acid ke coenzyme ea decarboxylation ea α-keto acid le antioididant ea nako e tobileng (e kopanyang li-radicals) le mohato o sa tobang. E kenya letsoho ho eketseha ha dikahare tsa glycogen ho sebete, ho fokotseha ha boemo ba khatello ea glucose maling a plasma le insulin. E nka karolo taolong ea metabolism ea lik'habohaedreite le lipids, e hlohlelletsa phapanyetsano ea cholesterol.

Thepa ea antioxidant ea thioctic acid e ka sireletsa liseleng hore li se ke tsa senyeha ka lihlahisoa tse bolileng, tsa fokotsa (ho lefu la tsoekere) ho thehoa ha lihlahisoa tsa liprotheine tse tsoelang pele liseleng tsa methapo, ho ntlafatsa phallo ea mali le methapo ea methapo, le ho eketsa litaba tsa mmele tsa glutathione antioxidant. Ho baka ho fokotseha hoa boemo ba glucose maling a mali, ho tsoekere ea tsoekere ho ama motsoako o mong oa tsoekere, ho fokotsa ho eketseha ha methapo ea methapo ea methapo (polyols), ka tsela eo ho fokotsa ho ruruha ha lisele tsa methapo.

Ho nka karolo ha thioctic acid ho metabolism ea mafura ho lumella biosynthesis ea phospholipids (ho kenyelletsa phosphoinositides) ho eketseha, ho ntlafatsa sebopeho se senyehileng sa membrane ea lisele. E khutlisetsa metabolism ea matla mme e tloaetse ho tsamaisoa ha methapo ea kutlo. E sitisa litlamorao tse chefo tsa metabolites ea joala, joalo ka acetaldehyde le pyruvic acid, mme e fokotsa sebopeho se feteletseng sa limolek'hule tsa mahala tsa oksijene. Ka ho fokolisa lipontšo tsa polyneuropathy (paresthesia, sensation e tukang, letsoalo le bohloko ba maoto le matsoho), e fokotsa endoneural hypoxia le ischemia.

Ts'ebeliso ea thioctic acid molemong oa kalafo ka mokhoa oa letsoai la ethylenediamine e fokotsa botebo ba litlamorao tse ka bang teng.

Mofumahali

Palo e phahameng ea thioctic acid e plasma ea metsotso e 30 kamora hore tsamaiso ea methapo (iv) e fihle ho 0,02 mg / ml, kakaretso ea khatello e ka bang 0.005 mg / h / ml.

Berlition 600 e tlosoa ho felisoa ha tsamaiso ea methapo ebile e ntlafatsoa haholo ke phello ea karolo ea pele ka sebete. Ho thehoa ha metabolites ho etsahala ka lebaka la oxidation ea lehlakore le thipa. Vd (bophahamo ba modumo) - hoo e ka bang 450 ml / kg. Tlhahiso ea plasma ka kakaretso ke 10-15 ml / min / kg. Ka tekanyo e kholo, 80-90% ea moriana o hokeloa ka liphio e le metabolites. Bophelo ba halofo ke hoo e ka bang metsotso e 25.

Litaelo tsa ho sebelisoa ha Berlition 600: mokhoa le litekanyetso

Tharollo e felileng ea moriana e etselitsoe infusion.

Hang-hang pele o sebelisoa, 1 ampoule e le 'ngoe ea mohopolo e qhaloa ka 250 ml ea tharollo ea chloride ea 0,9%.Tharollo e lokela ho fanoa ka / Drip, nako ea infusion e lokela ho ba bonyane lihora tse 0.5. Kaha sesebelisoa se sebetsang se na le khanya, botlolo e nang le tharollo e lokiselitsoeng e lokela ho roaloa ka foil ea aluminium ho e sireletsa hore e se ke ea pepesetsoa leseli.

Nako ea thupelo kapa tlhoko ea phetisetso ea eona e khethoa ke ngaka ka bo eona.

Litlamorao

• Tsamaisong ea 'mele ea ho itšireletsa mafung: hangata ha ho khonehe - ho kula (ho hlohlona, ​​lekhopho la letlalo, urticaria) maemong a ikhethileng - ts'oaetso ea anaphylactic,
• ho tsoa tsamaisong ea methapo: ka seoelo - diplopia, tlolo ea molao kapa phetoho ea tatso, letsoalo,
• lehlakoreng la metabolism: ka seoelo - ho fokotseha ha glucose ea plasma, mohlomong leseli, ho opeloa ke hlooho, ho fufuleloa, ho senyeha ha pono (matšoao a mmuso oa hypoglycemic),
• ho tsoa ho sheropoietic system: ka seoelo - purpura (hemorrhagic rash), thrombocytopathy, thrombophlebitis,
• Boitšoaro ba lehae: ha se hangata - ho chesa setsing sa ente,
• maikutlo a mang: khahlano le sekhahla sa ente e kenang ea ente e phahameng, keketseho ea nakoana ea khatello ea methapo, ho thatafalloa ho hema.

Bongata

Matšoao a bosholu ba thioctic acid ke: hlooho, ho nyekeloa ke pelo, ho hlatsa. Bakeng sa likotsi tse tebileng tsa tahi, ho kenyelletsa le taolo e sa lebelloang ea meriana e fetang 80 mg ka kilo e le 'ngoe ea boima ba' mele, ponahalo ea ho tsietsana ka kakaretso, ho ferekana kelellong, ho ferekana kelellong ke tšobotsi. Ntle le moo, nts'etsopele ea litšitiso tse phatlalalitsoeng tsa tekanyo ea acid-base, hypoglycemia (ho fihlela ho nts'etsopele ea mokokotlo), lactic acidosis, necrosis e matla ea mesifa ea marapo, hemolysis, letšoao la desensitised intravascular coagulation, ho hloleha ha litho tse ngata, ho hatella tšebetso ea moko oa masapo.

Phekolo: Ka lebaka la khaello ea litlhare tse itseng, ho bontšoa kalafo ea tšohanyetso maemong a sepetlele. Ho sebelisa mehato e nepahetseng ho tlosa matšoao a chefo, ho kenyelletsa le mekhoa ea tlhokomelo ea sejoale-joale e matla bakeng sa ho phekola linyeoe tse sokelang bophelo.

Ts'ebeliso ea hemodialysis, hemoperfusion kapa filtration mekhoa ka ho qobelloa ho tlosoa ha thioctic acid ha e na thuso.

Litaelo tse khethehileng

Bakuli ba nang le lefu la tsoekere ba hloka ho netefatsa ho shebella boemo ba khatello ea tsoekere maling ka bongata maling, haholo-holo qalong ea ts'ebeliso ea moriana. Haeba ho hlokahala, fokotsa tekanyetso ea li-acoglycemia tsa molomo kapa insulin ho thibela nts'etsopele ea hypoglycemia.

Kaha ethanol e fokotsa phello ea bongaka ea Berlition 600, ho thibetsoe ho noa joala le ho nka lihlahisoa tse nang le ethanol nakong ea kalafo le lipakeng tsa thupelo.

Khahlano le nalane ea ts'ebetso ea methapo ea methapo, litlamorao tsa hypersensitivity li ka hlaha, maemong a mokuli ka ho hlohlona, ​​malaise le matšoao a mang a ho se mamelle moriana, ho felisoa ha ts'ebetso ea ts'ebetso hang-hang.

Ho tsepamisa mohopolo ha Berlition 600 ho ka qhaloa feela ka tharollo ea 0.9% ea sodium chloride. Ho boloka tharollo e lokiselitsoeng ho lumelloa lihora tse ka bang tse tšeletseng, ha feela ho sirelelitsoe leseli.

Tšusumetso ho bokhoni ba ho khanna makoloi le mekhoa e rarahaneng

Ho hlokahala hore motho a be hlokolosi ha a etsa lintho tse ka bang kotsi le ho khanna. Kameho ea Berlition 600 mabapi le ho lebisa tlhokomelo le lebelo la karabelo ea psychomotor ea mokuli ha e e-so ithutoe, empa liphetoho tse ka ba teng tse kang ho tsekela kapa ho senyeha hoa pono li ka ama matšoao ana.

Ho sebelisana le lithethefatsi

E sebelisoa ka nako e le 'ngoe le Berlition 600:

• insulin, li-agent tsa hypoglycemic tsa molomo bakeng sa tsamaiso ea molomo: li matlafatsa phello ea tsona ea bongaka,
• ethanol: e fokotsa haholo phello ea kalafo ea thioctic acid,
• Litokisetso tsa tšepe: kenya letsoho ho theheng li-chelate complexes, ka hona, ho khothalletsoa ho qoba mefuta e joalo.
• cisplatin: thioctic acid e fokotsa ts'ebetso ea eona.

Bophelo ba Shelf ke lilemo tse 3.

Ketso ea pharmacological

Ha e le coenzyme ea mitochondrial multenzyme complexes, e nka karolo ho oxidative decarboxylation ea pyruvic acid le alpha-keto acid. E thusa ho fokotsa tsoekere ea mali le ho eketsa glycogen ho sebete, hammoho le ho hlola insulin.
Ka mofuta oa ts'ebetso ea biochemical, e haufi le livithamini tsa B. E nka karolo taolong ea metabolism ea lipid le carbohydrate, e matlafatsa metabolism ea cholesterol, mme e ntlafatsa ts'ebetso ea sebete. Tšebeliso ea letsoai la trometamol la thioctic acid (ho ba le karabelo e sa nke lehlakore) tharollo bakeng sa tsamaiso e kenelletseng e ka fokotsa botebo ba karabelo e mpe.

Contraindication

• lilemo tse 18
• nako ea kemaro
• sefuba
• nalane ea hypersensitivity ho likarolo tsa Berlition 600.

Litaelo tsa ho sebelisoa ha Berlition 600: mokhoa le litekanyetso

Tharollo e felileng ea moriana e etselitsoe infusion.

Hang-hang pele o sebelisoa, 1 ampoule e le 'ngoe ea mohopolo e qhaloa ka 250 ml ea tharollo ea chloride ea 0,9%. Tharollo e lokela ho fanoa ka / Drip, nako ea infusion e lokela ho ba bonyane lihora tse 0.5. Kaha sesebelisoa se sebetsang se na le khanya, botlolo e nang le tharollo e lokiselitsoeng e lokela ho roaloa ka foil ea aluminium ho e sireletsa hore e se ke ea pepesetsoa leseli.

Nako ea thupelo kapa tlhoko ea phetisetso ea eona e khethoa ke ngaka ka bo eona.

Litlamorao

• Tsamaisong ea 'mele ea ho itšireletsa mafung: hangata ha ho khonehe - ho kula (ho hlohlona, ​​lekhopho la letlalo, urticaria) maemong a ikhethileng - ts'oaetso ea anaphylactic,
• ho tsoa tsamaisong ea methapo: ka seoelo - diplopia, tlolo ea molao kapa phetoho ea tatso, letsoalo,
• lehlakoreng la metabolism: ka seoelo - ho fokotseha ha glucose ea plasma, mohlomong leseli, ho opeloa ke hlooho, ho fufuleloa, ho senyeha ha pono (matšoao a mmuso oa hypoglycemic),
• ho tsoa ho sheropoietic system: ka seoelo - purpura (hemorrhagic rash), thrombocytopathy, thrombophlebitis,
• Boitšoaro ba lehae: ha se hangata - ho chesa setsing sa ente,
• maikutlo a mang: khahlano le sekhahla sa ente e kenang ea ente e phahameng, keketseho ea nakoana ea khatello ea methapo, ho thatafalloa ho hema.

Bongata

Matšoao a bosholu ba thioctic acid ke: hlooho, ho nyekeloa ke pelo, ho hlatsa. Bakeng sa likotsi tse tebileng tsa tahi, ho kenyelletsa le taolo e sa lebelloang ea meriana e fetang 80 mg ka kilo e le 'ngoe ea boima ba' mele, ponahalo ea ho tsietsana ka kakaretso, ho ferekana kelellong, ho ferekana kelellong ke tšobotsi. Ntle le moo, nts'etsopele ea litšitiso tse phatlalalitsoeng tsa tekanyo ea acid-base, hypoglycemia (ho fihlela ho nts'etsopele ea mokokotlo), lactic acidosis, necrosis e matla ea mesifa ea marapo, hemolysis, letšoao la desensitised intravascular coagulation, ho hloleha ha litho tse ngata, ho hatella tšebetso ea moko oa masapo.

Phekolo: Ka lebaka la khaello ea litlhare tse itseng, ho bontšoa kalafo ea tšohanyetso maemong a sepetlele. Ho sebelisa mehato e nepahetseng ho tlosa matšoao a chefo, ho kenyelletsa le mekhoa ea tlhokomelo ea sejoale-joale e matla bakeng sa ho phekola linyeoe tse sokelang bophelo.

Ts'ebeliso ea hemodialysis, hemoperfusion kapa filtration mekhoa ka ho qobelloa ho tlosoa ha thioctic acid ha e na thuso.

Litaelo tse khethehileng

Bakuli ba nang le lefu la tsoekere ba hloka ho netefatsa ho shebella boemo ba khatello ea tsoekere maling ka bongata maling, haholo-holo qalong ea ts'ebeliso ea moriana. Haeba ho hlokahala, fokotsa tekanyetso ea li-acoglycemia tsa molomo kapa insulin ho thibela nts'etsopele ea hypoglycemia.

Kaha ethanol e fokotsa phello ea bongaka ea Berlition 600, ho thibetsoe ho noa joala le ho nka lihlahisoa tse nang le ethanol nakong ea kalafo le lipakeng tsa thupelo.

Khahlano le nalane ea ts'ebetso ea methapo ea methapo, litlamorao tsa hypersensitivity li ka hlaha, maemong a mokuli ka ho hlohlona, ​​malaise le matšoao a mang a ho se mamelle moriana, ho felisoa ha ts'ebetso ea ts'ebetso hang-hang.

Ho tsepamisa mohopolo ha Berlition 600 ho ka qhaloa feela ka tharollo ea 0.9% ea sodium chloride. Ho boloka tharollo e lokiselitsoeng ho lumelloa lihora tse ka bang tse tšeletseng, ha feela ho sirelelitsoe leseli.

Tšusumetso ho bokhoni ba ho khanna makoloi le mekhoa e rarahaneng

Ho hlokahala hore motho a be hlokolosi ha a etsa lintho tse ka bang kotsi le ho khanna. Kameho ea Berlition 600 mabapi le ho lebisa tlhokomelo le lebelo la karabelo ea psychomotor ea mokuli ha e e-so ithutoe, empa liphetoho tse ka ba teng tse kang ho tsekela kapa ho senyeha hoa pono li ka ama matšoao ana.

Bokhachane le pelehi

Ts'ebeliso ea lithethefatsi e hanyetsoa nakong ea ho emara le ho lactation, ka lebaka la ho haelloa ke boiphihlelo bo lekaneng ba kliniki kalafong ea bakuli bona.

Sebelisa bongoaneng

Ho latela litaelo, Berlition 600 e ke ke ea khethoa kalafo ea bana le bacha ba ka tlase ho lilemo tse 18, kaha ts'ireletso ea ts'ebeliso ea lithethefatsi le ts'ebetso ea eona ha e so theoe.

Ho sebelisana le lithethefatsi

E sebelisoa ka nako e le 'ngoe le Berlition 600:

• insulin, li-agent tsa hypoglycemic tsa molomo bakeng sa tsamaiso ea molomo: li matlafatsa phello ea tsona ea bongaka,
• ethanol: e fokotsa haholo phello ea kalafo ea thioctic acid,
• Litokisetso tsa tšepe: kenya letsoho ho theheng li-chelate complexes, ka hona, ho khothalletsoa ho qoba mefuta e joalo.
• cisplatin: thioctic acid e fokotsa ts'ebetso ea eona.

Bophelo ba Shelf ke lilemo tse 3.

Sebopeho le mofuta oa tokollo

ka har'a likhalase tsa khalase tse sootho tsa 12 ml, ka lebokoseng la karete ea li-ampoules tse 5, 10 kapa 20.

ka mokotla oa lithutsoana tsa li-pcs tse 10, ka lebokoseng la karete ea lipakete tse 3, 6 kapa 10.

Tlhaloso ea foromo ea litekanyetso

Tharollo ea ente: 'mala o phatsimang oa' mala o mosehla o bosehla bo benyang.
ho pota, matlapa a biconvex a mmala o moputsoa, ​​a nang le notch bakeng sa ho arohana ka lehlakoreng le le leng.

Feature

Thioctic acid - e leng antioxidant ea endo native (e kopanyang li-radicals tsa mahala), e thehoa 'meleng nakong ea oxidative decarboxylation ea alpha-keto acid.

Ketso ea pharmacological

Ha e le coenzyme ea mitochondrial multenzyme complexes, e nka karolo ho oxidative decarboxylation ea pyruvic acid le alpha-keto acid. E thusa ho fokotsa tsoekere ea mali le ho eketsa glycogen ho sebete, hammoho le ho hlola insulin.
Ka mofuta oa ts'ebetso ea biochemical, e haufi le livithamini tsa B. E nka karolo taolong ea metabolism ea lipid le carbohydrate, e matlafatsa metabolism ea cholesterol, mme e ntlafatsa ts'ebetso ea sebete. Tšebeliso ea letsoai la trometamol la thioctic acid (ho ba le karabelo e sa nke lehlakore) tharollo bakeng sa tsamaiso e kenelletseng e ka fokotsa botebo ba karabelo e mpe.

Mofumahali

Ha e noa ka molomo, e kenella ka potlako le ka botlalo ho tsoa ho tšilo ea lijo (ho kenella ka ho kenngoa ka lijo tse fokolang). Nako ea ho fihla C max ke metsotso e 40-60. Bioavailability ke 30%. E na le phello ea "mokhoa oa pele" ka sebete. Ho thehoa ha metabolites ho etsahala ka lebaka la oxidation ea lehlakore le thipa. Boholo ba kabo e ka ba 450 ml / kg Litsela tse kholo tsa metabolic ke oxidation le conjugation. Thioctic acid le metabolites ea eona li hlahisoa ke liphio (80-90%). T 1/2 - metsotso e 20-50. Kakaretso ea plasma Cl - 10-15 ml / min.

Matšoao a lithethefatsi Berlition 300

Lefu la tsoekere le joala bo tahang, steatohepatitis ea li-etiology tse fapa-fapaneng, sebete sa mafura, ho tahoa ho sa feleng.

Contraindication

Hypersensitivity, boimana, matsoele. Se ke oa fana ka taelo ho bana le lilemong tsa bocha (ka lebaka la ho hloka tsebo ea bongaka ka ts'ebeliso ea bona ea lithethefatsi).

Tekanyetso le tsamaiso

Iv . Mefuteng e matla ea IV polyneuropathy, 12-24 ml (300-600 mg ea alpha lipoic acid) ka letsatsi bakeng sa libeke tsa 2-4. Bakeng sa sena, li-ampoules tsa 1-2 tsa moriana li hlapolotsoe ka 250 ml ea tharollo ea sodium chloride le ho tsamaisoa ka tlase ho metsotso e ka bang 30. Nakong e tlang, ba fetoha pheko ea tlhokomelo le Berlition 300 ka mokhoa oa lipilisi ka lethal dose ea 300 mg ka letsatsi.

Bakeng sa kalafo ea polyneuropathy - 1 tafole. Makhetlo a 1-2 ka letsatsi (300-600 mg ea alpha lipoic acid).

Litlhokahalo tsa polokeho

Nakong ea kalafo, motho o lokela ho hana ho sebelisa lino tse tahang (joala le lihlahisoa tsa lona li fokolisa phello ea kalafo).

Ha o sebelisa sethethefatsi, o lokela ho lekola boemo ba tsoekere ea mali khafetsa (haholo-holo mohato oa pele oa kalafo). Maemong a mang, ho thibela matšoao a hypoglycemia, ho ka hlokahala ho fokotsa tekanyetso ea insulin kapa moemeli oa antidiabetesic ea molomo.

Tšobotsi ea kalafo

Karolo e sebetsang ea sebopeho sa moriana Berlition ke alpha-lipoic acid, hape e tsejoang e le thioctic. Ntho ena e fumaneha ka har'a litho tse ngata tsa motho, empa libaka tsa mantlha tsa "ho fallisoa" ke pelo, sebete le liphio. Alpha-lipoic acid ke antioxidant e matla, e thusa ho fokotsa litlamorao tsa metsoako e mebe. E boetse e sireletsa sebete 'me e thusa ho tsosolosa tšebetso ea eona.

Thioctic acid e le karolo ea lithethefatsi tse tloaelehileng tsa lipid metabolism, e fana ka phokotso ea tsoekere ea mali, hape e thusa ho theola boima ba 'mele. Phello ea eona ea biochemical e tšoana le livithamini tsa sehlopha sa B. E kenya tšebetsong lits'ebetso tsa "cholesterol" tsa mmele, e sirelletsa mmele ho thehwa ha methapo ea mali ea atherosselotic, e netefatsang ho bola ha bona le ho itokolla kapele.

Likarolo tse sebetsang tsa lithethefatsi li fokotsa palo ea lihlahisoa tsa enzymatic tse etsahalang 'meleng. Sena se o lumella ho ntlafatsa ts'ebetso ea neuro-peripheral, eketsa boemo ba glutathione - antioxidant e matla e hlahisoang 'meleng oa motho. E fana ka ts'ireletso khahlanong le tšoaetso ea vaerase, mafu a fapaneng le lintho tse kotsi.

Tlas'a tšusumetso ea moemeli, lits'ebetso tsa tsosoloso le matla ka har'a lisele li sebetsa ebile li potlakile. Sena se etsa hore ho khonehe ho kenyelletsa Berlition ea lithethefatsi ka sebopeho sa kalafo e rarahaneng ea maloetse a mangata.

Indasteri ea meriana e etsa Berlition ka mefuta e 'meli e fapaneng ea litekanyetso. Tsena ke matlapa le ho emisoa ha liente ka li-ampoules - Berlition 600. Matlapa a 300 a Berlition a rekisoa ka tsela ea lipoleiti tsa likotoana tse 10. Li na le 300 mg ea ntho e sebetsang. Ntle le asiti ea thioctinic, li na le likholomo tse nyane tsa colloidal silicon diode, magnesium stearate, povidone, croscarmellose sodium, lactose le microscopic cellulose.

Ha e le mohopolo bakeng sa ho hlophisoa ha tharollo, e na le 25 mg / ml ea ntho e sebetsang. Ntle le moo, ho tsepamisa mohopolo ho kenyelletsa likarolo tse thusang: metsi a ho entoa, ethylene diamine le propylene glycol.

Li-analogues tsa Berlition li na le ntho ea mantlha e tšoanang le sehlahisoa sa mantlha - acid ea thioctic. Leha ho le joalo, li-analogues li fumaneha feela ka mokhoa oa matlapa le likhabapo. Ha ho na lipelaelo tsa metsi bakeng sa ente ea intravenous.

Ho khethoa le li-contraindication

Tšoaetso ea ts'ebeliso ea lithethefatsi ke atherosulinosis ea methapo ea methapo ea kutlo, li-pathologies tsa sebete tsa methapo e fapa-fapaneng ea tahi, ho tahoa, neuropathy haeba ho le joala kapa lefu la tsoekere. Ntle le moo, Berlition 600 le mofuta oa eona oa letlapa li bontšoa bakeng sa mefuta e fapaneng ea osteochondrosis.

Setlhare se na le likhohlano tse 'maloa. Berlition 600 ha e laeloe hypersensitivity le ho se mamellane ha ntho e sebetsang le likarolo tse ling tsa lithethefatsi, hammoho le galactosemia le ho se mamellane ha lactose. Ha e fuoe bana ba ka tlase ho lilemo tse 18.Ntle le moo, ha ho ratehe ho nka Berlition ho bo-mme le basali nakong ea ho beleha ngoana, ka lebaka la hore ha ho na bopaki bo ngotsoeng ba polokeho ea moriana.

Tekanyetso le mokhoa oa tsamaiso li lokela ho khethoa ke ngaka e eang. Motsoako oa litekanyetso o ipapisitse le bokuli le mofuta oa moriana. Hangata, ho ente ente ho loants'a maemo a methapo, maemong a mang ho sebelisoa litafole. Liphetoho li kanna tsa etsoa kalafong ea kalafo, empa hona ho lokela ho khethoa ke setsebi.

Letlapa le lokela ho nkuoa le felletse ntle le ho hlafuna ebe le hlatsuoa ka metsi a mangata. Nako e ntle ke hoseng, halofo ea hora pele ho lijo. Tsela ea kalafo e itšetlehile ka bokuli bo fumanoeng, boemo ba mokuli le bokhoni ba 'mele ba hae ba ho fola. Ha e le molao, e qala ho tloha libeke tse 'maloa ho isa ho khoeli, empa haeba ho hlokahala, e ka eketsoa.

Kamora ho fela ha phekolo ea mantlha, joalo ka prophylaxis ea lipontšo tse ncha le ho mpefala ha lefu lena, moriana o ka fetisoa ka tekanyo e fokotsehileng.

Ts'ebeliso ea Berlition 600 concentrate e khethoa motheong oa linyeoe. Hangata, tsena ke mathata a tsamaiso ea methapo, a hlahisoang ke liso tsa methapo e nyane ea mali, ho tahoa haholo kapa boemo bo sa tsebeng ha mokuli a sa khone ho inkela moriana.

Pele o beha lerotholi, sekhahla sa lithethefatsi se hlapolotsoe ka letsoai. Ho hlophisoa ha tharollo ho lokela ho etsoa hang-hang pele ho ente e le hore e se ke ea lahleheloa ke thepa ea eona ea kalafo. Ho se khonehe ha leseli le khanyang ka tharollo e seng e lokisitsoe. Botoro ka eona e lokela ho phutheloa ka pampiri e tenya ea pampiri, foil kapa opaque polyethylene.

Haeba ho na le tlhoko ea ho hlahisa moriana ka potlako, empa ha ho na tharollo ea saline, ho kenyelletsoa ho kenella ho tsepamiso. Bakeng sa sena, ho sebelisoa syringe le pompo ea infusion. Sena ke sesebelisoa se ikhethileng se u lumellang ho laola phepelo ea metsi ho mokuli. Sekhahla sa kenyelletso ea mohopolo ke boholo ba 1 ml / min. Ho e fetisa ho thibetsoe ka thata.

Maemong a mang, tsamaiso ea methapo ea methapo ea kutlo e lumelletsoe. Empa sena se ea ho latela moralo o itseng: ho thibetsoe ho enta tharollo e fetang 2 ml sebakeng se le seng. Kahoo, ka ho kenyelletsa ampoule e nang le bophahamo ba 24 ml, u tla tlameha ho etsa likarolo tse 12 tsa likarolo tse fapaneng tsa mesifa.

Litlamorao

Liphuputso tse ngata tsa kliniki li bontšitse hore ka linako tse ling ho sebelisa meriana ho ka baka litlamorao ho tsoa ho litho tse fapaneng le litsamaiso tsa 'mele. Ho feta moo, lilemo kapa bong ba bakuli ha li ame ho hlaha ha bona. Hangata, li ka hlaha ho banna le basali, ho bacha le ho bakuli ba tsofetseng.

Setlhare se ka u qholotsa ho nyekeloa ke pelo, ho hlatsa, ho opeloa ke pelo. Tsamaiso ea methapo e ka arabela litlhare ka litlolo tse sa senyeheng tsa ho latsoa, ​​ho tsitsipana le maikutlo a ho hlonepha mahlong.

Matlapa a Berlition le tharollo ea ente e ama lits'ebetso tsa metabolic. Ho fokotseha hoa boemo ba tsoekere maling ho boletsoe, 'me ka lebaka leo, ho ikoahlaea, hlooho e bohloko, mofufutso oa hlaha. Maemong a mang, urticaria, lekhopho la letlalo, ho hlohlona, ​​le metsoako ea mafu a ka hlaha.

Bohloko bo tukang bo ka utluoa libakeng tsa ente. Taba ena e netefatsoa ke litlhahlobo tsa bakuli ba fuoeng liente tsa Berlition. Ntle le moo, tharollo e potlakileng haholo e ka tsosa maikutlo a ho imeloa hloohong le ho hema hanyane.

Matšoao a bosholu

Ho ja hampe le ho fetella ka tekanyetso e hlokahalang ho ka baka tšebeliso e feteletseng ea moriana le ho hlaha hoa matšoao a sa thabiseng: ho tsitsipana, ho ferekana kelellong, hlooho e bohloko, ho nyekeloa le pelo le ho hlatsa, ho fokotseha ho hoholo ha tekanyo ea tsoekere maling le phallo ea psychomotor. Ntle le moo, acidity e ka eketseha ka matla 'meleng, tšebetso ea litho tse ling le ts'ebetso ea ho ts'oaroa ha mali li ka sitisoa.

Berlition e bua ka lithethefatsi tse ntlafatsang metabolism le tšebetso ea lisele tsa sebete. Sesebelisoa se fokotsa khatello ea k'holeseterole e liseleng tsa mali, e sebelisetsoa ho phekola mafu a sebete, atherosulinosis, lefu la tsoekere le joala bo tahang.

Tlhaloso ea lithethefatsi, foromo ea ho lokolloa le sebopeho

Sesebelisoa se na le litlamorao tse ngata:

• fokotsa lipid
• ho potlakisa tšebetso ea metabolism ea cholesterol,
• e ntlafatsa ts'ebetso ea sebete,
• e theola tsoekere e maling.

Berlition ke sethethefatsi sa antioxidant. E khetholloa ke phello ea vasodilating.

Sesebelisoa se thusa ho potlakisa ts'ebetso ea ho hlaphoheloa ha lisele le ho potlakisa lits'ebetso tsa metabolic ho tsona. Motsoako ona o sebelisoa ka mafolofolo kalafong ea lefu la masapo le manonyeletso.

Berlition e etsoa ka mefuta e 'maloa:

• Matlapa a 300 mg
• ka sebopeho sa mohopolo o sebelisoang ka ente (300 le 600 mg).

Karolo e ka sehloohong ke thioctic acid. E le karolo ea tlatsetso, Ethylenediamine e teng le metsi a ente. Feta ka har'a li-gates le propylene glycol.

Ho hlophisoa ha matlapa ho kenyelletsa magnesium stearate le povidone. Ho na le cellulose ka sebopeho sa li-microcrystals, silicon dioxide, hammoho le lactose le croscarmellose sodium.

Maikutlo a bakuli le litheko tsa lithethefatsi

Ho tsoa ho litlhahlobo tsa mamello, re ka fihlela qeto ea hore moriana o mamelletsoe hantle. Litlamorao li na le seoelo ebile li nyane.

Setlhare se ne se laetsoe kalafo ea osteochondrosis. Ngaka e neng e le teng e ile ea hlalosa hore moriana o busetsa phallo ea mali. Matsatsi a 'maloa ka mor'a ho entoa, Berlition o ile a ikutloa a ntlafala haholo. Ke habohlokoa ho hlokomela hore ntle le moo ke ile ka tšoaroa ka Chondroxide le Piracetam. Lefa go ntse jalo, e nthusitse.

Setlhare se seholo. O ile a fuoa kalafo ka moriana ona mme a imoloha. Ho ne ho lula ho e-na le maikutlo a tukang maotong le letsoalo ho bona.

Lintho tsa video tse mabapi le lefu la tsoekere, thibelo ea lona le kalafo:

Litsenyehelo tsa moriana libakeng tse fapaneng li na meelelo e fapaneng 'me ho latela mofuta oa tsona:

• Matlapa a 300 mg - li-ruble tse 683-855,
• 300 mg ampoule - li-ruble tse 510-725,
• Li-ampoule tsa 600 mg - li-ruble tse 810-976.

Berlition ke lithethefatsi tse thehiloeng ho alpha lipoic acid.

Mabitso, liforomo tsa tokollo le sebopeho sa Berlition

Mabitso a tloaelehileng "Berlition 300" kapa "Berlition 600" a sebelisoa hangata ho bontša litekanyetso tsa moriana. Ho tsepamisa mohopolo ha ho etsoa tharollo khafetsa ho thoe feela ka "li-Berlition". Ka nako e 'ngoe u ka utloa ka li-capslop tsa Berlition, leha ho le joalo, kajeno ha ho na mofuta o joalo oa litekanyetso, mme motho o na le mohopolo oa ho fapana ha lithethefatsi bakeng sa tsamaiso ea molomo.

Joaloka motsoako o sebetsang, Berlition e na le alpha lipoic acid hape e bitsoang thioctic . E le likarolo tse thusang, tsepamisa mohopolo bakeng sa ho hlophisoa ha tharollo li na le propylene glycol le metsi a ente. 'Me matlapa a Berlition e le likarolo tse thusang a na le lintho tse latelang:

• Microcrystalline cellulose,
• Magnesium stearate,
• Sodium-paleptos
• Povidone
• Silicon khase ea hydrate.

Matlapa a Berlition a fumaneha ka mekotla ea likotoana tse 30, 60 kapa 100, 300 mg tsepamisang maikutlo - 5, 10 kapa 20 ampoules, le 600 mg concentrate - li-ampoules tse 5 feela.

Ho tsepamisa mohopolo ho matšoao a hlakileng a tiisitsoeng ka bongata. Metsoako ka boeona e hlakile, e pentiloe ka 'mala o botala bo bosehla. Matlapa a na le sebopeho se chitja, sa biconvex mme a 'mala o mosehla. Ho na le kotsi sebakeng se le seng sa matlapa. Ka phoso, letlapa le na le 'mala o sa lekanang, oa granular le pente e mosehla.

Litlamorao tsa kalafo ea Berlition

Ho fihlella ho fokotseha hoa khatello ea tsoekere ea mali ho etsahala ka ho eketsa kutloisiso ea lisele ho insulin le ho fokotsa ho hanyetsa.Ka lebaka la sena, ho bakuli ba nang le lefu la tsoekere mellitus, ho pepesetsoa ha glucose bokaholimo ba methapo ea mali hoa fokotseha le matla a glycosylation le ts'enyo ea radicals ea mahala ea lisele tsa methapo ea fokotseha. Sena, se fokotsa hypoxia ea methapo ea methapo le lisele, se li sireletsa ho li-radicals tsa mahala, hape se ntlafatsa phepo ea tsona le ho sebetsa. Ka lebaka leo, ho bakuli ba nang le lefu la tsoekere mellitus, neuropathy e amanang le glycosylation e ngata e thibeloa. Ka mantsoe a mang, Berlition e ntlafatsa mosebetsi oa methapo ea kutlo, e emisa matšoao a polyneuropathy (ho chesa, ho utloa bohloko, ho akheha, joalo-joalo).

Litaelo tsa ho sebelisoa ha Berlition ho ampoules (Berlition 300 le 600)

Li-infusions tsa Berlition li sebelisoa haholo ho phekola li-neuropathies. Phekolo ea chefo, atherosclerosis le mafu a sebete e etsoa matlapeng. Leha ho le joalo, haeba motho a sa khone ho sebelisa lipilisi, o kenngoa le Berlition ka methapo ea methapo ea 300 mg ka letsatsi (1 ampoule ea 12 ml).

Ho lokisa tharollo bakeng sa infravenous infusion, ampoule e le 'ngoe ea Berlition 12 ml kapa 24 ml (300 mg kapa 600 mg) e tlameha ho kenngoa ka 250 ml ea saline ea mmele. Bakeng sa kalafo ea neuropathy, tharollo e nang le 300 mg kapa 600 mg ea Berlition e fanoa hang ka letsatsi bakeng sa libeke tse peli ho isa ho tse nne. Ebe ba qala ho nka Berlition matlapeng a tekanyetso ea 300 mg ka letsatsi.

Tharollo ea tsamaiso ea methapo e tlameha ho lokisoa hang-hang pele e sebelisoa, kaha e lahleheloa ke thepa ea eona kapele. Tharollo e felileng e lokela ho sireletsoa ke letsatsi, e koahele sejana ka foil kapa pampiri e tenya ea opaque. Metsoako e kenelletseng e ka sebelisoa lihora tse fetang tse tšeletseng haeba tharollo e ne e bolokiloe sebakeng se lefifi.

Haeba ho sa khonehe ho lokisa tharollo bakeng sa infusion, joale ho tsepamisa mohopolo ho sa lekanyetsoang ho ka tsamaisoa kahare ho ts'ebeliso ea syringe le perfuser. Maemong ana, ho tsepamisa mohopolo ho lokela ho tsamaisoa butle, eseng kapele ho feta 1 ml ka motsotso. Sena se bolela hore ampoule ea 12 ml e lokela ho fuoa bonyane metsotso e 12, le 24 ml - ka ho latellana, metsotso e 24.

Berlition e ka tsamaisoa ka mokhoa o ts'oanang ka li-2 ml tsa ho tsepamisa mohopolo ka ente e ngoe. Ho feta 2 ml ea ho tsepamisa mohopolo ho ke ke ha kenella sebakeng se le seng sa mesifa. Sena se bolela hore molemong oa ho hlahisa li-ml tse 12 tsa concentrate (1 ampoule) ho tla hlokahala hore ho etsoe liente tse 6 likarolong tse fapaneng tsa mesifa, jj.

Ho sebelisana le lithethefatsi tse ling

Ka lebaka la bokhoni ba ho sebelisana ka lik'hemik'hale le li-ion tsa tšepe, ha ho kgothaletsoe ho nka litokisetso tsa magnesium, iron, kapa calcium ka mor'a ho nka Berlition, kaha li-digestibility tsa bona li tla fokotsoa. Tabeng ena, ho khothalletsoa ho nka Berlition hoseng, le litokisetso tse nang le likhomphutha tsa tšepe thapama kapa ka shoalane. Hoa tšoana le ka lihlahisoa tsa lebese tse nang le calcium e ngata.

Lino tse tahang le joala la ethyl, tse fumanehang mefuteng e fapaneng ea methapo, li fokotsa katleho ea Berlition.

Ho tsepamisa mohopolo ha Berlition ha ho lumellane le tharollo ea tsoekere, fructose, dextrose le Ringer, hobane thioctic acid e baka metsoako e sa sebetseng hantle ea limolek'hule le tsoekere.

Berlition e ntlafatsa phello ea lithethefatsi tsa hypoglycemic le insulin, ka hona, ka ts'ebeliso e le 'ngoe, ho hlokahala hore ho fokotsa litekanyetso tsa bona.

Berlition (300 le 600) - li-analogues

• Lipamide - matlapa
• Lipoic acid - matlapa le tharollo ea ente ea methapo ea kutlo,
• Lipothioxone - ho tsepamisa mohopolo ha ho lokisoa tharollo ea tsamaiso ea methapo,
• Neyrolipon - likhapha le ho tsepamisa mohopolo ho lokiseng tharollo bakeng sa tsamaiso ea methapo,
• Oktolipen - likhakeletsi, matlapa le ho tsepamisa mohopolo molemong oa ho lokisa tharollo bakeng sa tsamaiso ea methapo,
• Thiogma - matlapa, tharollo le ho tsepamisa mohopolo bakeng sa ts'ebetso
• Thioctacid 600 T - tharollo bakeng sa tsamaiso ea methapo,
• Thioctacid BV - matlapa,
• Thioctic acid - matlapa,
• Tialepta - matlapa le tharollo ea infusion,
• Thiolipone - tsepamisa maikutlo ha ho etsoa tharollo ea tharollo ea methapo,
• Espa-Lipon - matlapa 'me a tsepamise mohopolo ho lokiseng tharollo bakeng sa tsamaiso ea methapo.

Menahano ea litlatse Meriana e latelang ke:

• Bana ba Bifiform - matlapa a qhekelloang,
• Gastricumel - matlapa a homeopathic,
• Phetello - li-capsules,
• Orfadine - likhechana,
• Kuvan - lipilisi.

Berlition (300 le 600) - litlhahlobo

Litlhahlobo tse mpe tsa Berlition li fokola haholo mme li bakoa haholo ke ho haella ha phello e lebelletsoeng ho tsoa ho eona. Ka mantsoe a mang, batho ba ne ba itšetleha ka phello e le 'ngoe,' me phello e ne e fapane hanyane. Boemong bona, ho na le ho soetseha ho matla ho lithethefatsi, mme batho ba tlohela tlhahlobo e mpe.

Ntle le moo, lingaka tse khomarelang ho boloka ka hloko melao-motheo ea bongaka bo thehiloeng ho bopaki li siea litlhahlobo tse mpe ka Berlition. Kaha ts'ebetso ea bongaka ea Berlition ha e so bonoe, ba lumela hore lithethefatsi ha li na kelello ebile ha li hloke kalafo ea li-neuropathies ho lefu la tsoekere le maemo a mang kapa maloetse. Leha ho bile le ntlafatso e tlisoang ke maemo a batho, lingaka li nka hore Berlition ha e na thuso ebile e siea litlhahlobo tse mpe ka eena.

Berlition kapa Thioctacid?

Thioctacid bakeng sa tsamaiso ea methapo e rekisoa ka tlasa lebitso la khoebo Thioctacid 600 T, 'me e na le 100 mg kapa 600 mg ea ntho e sebetsang ho ampoule e ngoe le e ngoe. Berlition ea ente e fumaneha litekanyetso tsa 300 mg le 600 mg. Ka hona, haeba ho hlokahala, tšebeliso ea lipoic acid ho litekanyetso tse tlase e loketse ho thioctacid. Haeba o hloka ho kenya 600 mg ea lipoic acid, joale o ka khetha sesebelisoa leha e le sefe se thehiloeng ho lithahasello tsa hau. Berlition le Thioctacid ka bobeli li fumaneha ka foromo ea lipilisi, ka hona, haeba ho hlokahala hore u sebelise chelete bakeng sa tsamaiso ea molomo, u ka khetha sethethefatsi leha e le sefe.

Mohlala, matlapa a Thioctacid a fumaneha ka litekanyetso tsa 600 mg, le Berlition - 300 mg, kahoo ea pele e lokela ho nkuoa e le 'ngoe ka letsatsi,' me ea bobeli ka ho latellana, e 'meli. Ho tloha ponong ea ho nolofalletsa, Thioctacid ea rateha, empa haeba motho a sa hlajoe ke lihlong ka lebaka la tlhoko ea ho nka matlapa a mabeli letsatsi le leng le le leng, joale Berlition e mo loketse.

Ntle le moo, ho na le mamello ea lithethefatsi ho latela maemo a 'mele oa motho ka mong. Hona ho bolela hore motho a le mong o mamella Berlition hamolemo, mme e mong - Thioctacid. Boemong bo joalo, hoa hlokahala ho khetha moriana o mamelloang hamolemo ebile o sa bake litla-morao. Empa sena se ka khethoa feela teko ka ho leka ho sebelisa lithethefatsi tse fapaneng.

Leha ho le joalo, haeba matšoao a kliniki a le matla haholo kapa matlapa a sa thusa, ho khothalletsoa ho fana ka lithethefatsi tse nang le alpha-lipoic acid kahare. Boemong bo joalo, ho hlokahala ho sebelisa Berlition ka mokhoa oa ho tsepamisa mohopolo bakeng sa ho hlophisoa ha tharollo bakeng sa tsamaiso ea methapo, kapa Thioctacid 600 T.

Berlition (matlapa, ampoules, 300 le 600) - theko

Hajoale, likhoebong tsa litoropo tsa Russia, litšenyehelo tsa Berlition li ka tsela e latelang:

• Matlapa a Berlition 300 mg 30 likotoana - 720 - 850 li-ruble,
• Berlition tsepamisa kelello 300 mg (12 ml) li-ampoules tse 5 - 510 - 721 li-ruble,
• Berlition tsepamisa kelello 600 mg (24 ml) li-ampoules tse 5 - 824 - 956 li-ruble.

Litla-morao tsa Berlition

Ts'oaetso ea "metabolism" ea "glucose metabolism" (hypoglycemia), lintho tse kulisang (ho kenyelletsa ho makala ha anaphylactic), le ts'ebetso ea ho lieha kapa ho lieha ho phefumoloha, khatello e matla ea intracranial, letsoalo, diplopia, hemorrhages ea letlalo le li-membrane tsa mucous.

Matšoao a ho sebelisoa

Litaelo tsa tšebeliso ea lithethefatsi Berlition

Matlapa a Berlition

Ho feta moo, matlapa a Berlition a ka nkuoa e le karolo ea kalafo e rarahaneng ea mafu a sebete, chefo le atherosclerosis, e le 'ngoe ka nako.Nako ea ho amoheloa e khethoa ke sekhahla sa ho hlaphoheloa.

Litaelo tsa ho sebelisoa ha Berlition ho ampoules (Berlition 300 le 600)

Li-infusions tsa Berlition li sebelisoa haholo ho phekola li-neuropathies. Phekolo ea chefo, atherosclerosis le mafu a sebete e etsoa matlapeng. Leha ho le joalo, haeba motho a sa khone ho sebelisa lipilisi, o kenngoa le Berlition ka methapo ea methapo ea 300 mg ka letsatsi (1 ampoule ea 12 ml).

Ho lokisa tharollo bakeng sa infravenous infusion, ampoule e le 'ngoe ea Berlition 12 ml kapa 24 ml (300 mg kapa 600 mg) e tlameha ho kenngoa ka 250 ml ea saline ea mmele. Bakeng sa kalafo ea neuropathy, tharollo e nang le 300 mg kapa 600 mg ea Berlition e fanoa hang ka letsatsi bakeng sa libeke tse peli ho isa ho tse nne. Ebe ba qala ho nka Berlition matlapeng a tekanyetso ea 300 mg ka letsatsi.

Tharollo ea tsamaiso ea methapo e tlameha ho lokisoa hang-hang pele e sebelisoa, kaha e lahleheloa ke thepa ea eona kapele. Tharollo e felileng e lokela ho sireletsoa ke letsatsi, e koahele sejana ka foil kapa pampiri e tenya ea opaque. Metsoako e kenelletseng e ka sebelisoa lihora tse fetang tse tšeletseng haeba tharollo e ne e bolokiloe sebakeng se lefifi.

Haeba ho sa khonehe ho lokisa tharollo bakeng sa infusion, joale ho tsepamisa mohopolo ho sa lekanyetsoang ho ka tsamaisoa kahare ho ts'ebeliso ea syringe le perfuser. Maemong ana, ho tsepamisa mohopolo ho lokela ho tsamaisoa butle, eseng kapele ho feta 1 ml ka motsotso. Sena se bolela hore ampoule ea 12 ml e lokela ho fuoa bonyane metsotso e 12, le 24 ml - ka ho latellana, metsotso e 24.

Berlition e ka tsamaisoa ka mokhoa o ts'oanang ka li-2 ml tsa ho tsepamisa mohopolo ka ente e ngoe. Ho feta 2 ml ea ho tsepamisa mohopolo ho ke ke ha kenella sebakeng se le seng sa mesifa. Sena se bolela hore molemong oa ho hlahisa li-ml tse 12 tsa concentrate (1 ampoule) ho tla hlokahala hore ho etsoe liente tse 6 likarolong tse fapaneng tsa mesifa, jj.

Berlition - melao ea ho ts'oara lerotholi

E le solvent bakeng sa ho tsepamisa mohopolo, ho ka sebelisoa feela letsoai le letsoalo.

Litaelo tse khethehileng

Bakuli ba nang le lefu la tsoekere, qalong ea kalafo le Berlition, ba lokela ho hlokomela tsoekere e maling maling makhetlo a 1-3 ka letsatsi. Haeba khatello ea "glucose" nakong ea ts'ebeliso ea Berlition e fokotsehile ho fihla moeling o tlase, hoa hlokahala ho fokotsa litekanyetso tsa li-insulin kapa li-hypoglycemic agents.

Ka tsamaiso e kenelletseng ea Berlition, karabelo ea ho kulisa e ka hlaha ka mokhoa oa ho hlohlona kapa mala. Maemong ana, o lokela ho emisa ho qala tharollo hang-hang.

Haeba tharollo e fanoa ka potlako haholo, o ka ba le maikutlo a boima hloohong, makhopho le pono e habeli. Matšoao ana a nyamela a le mong mme ha a hloke ho felisoa ha moriana.

Nakong eohle ea kopo ea Berlition, tlhokomelo e lokela ho nkuoa ha u khanna koloi le mosebetsi o hlokang tlhokomelo e kholo.

Bongata

Ha u nka kapa ho kenella ka hare ho 5000 mg ea Berlition, overdose e nang le matšoao a matla e ka hlaha, joalo ka:

• Psychomotor agaring,
• Ho hloka tsebo
• Maqhubu
• Acidosis
• Ho fokotseha ho hoholo ha tsoekere ea glucose maling ho fihlela ho coma ea hypoglycemic,
• Skeletal misuli necrosis,
• DIC
• Erythrocyte hemolysis,
• Bone mokopu khatello
• Ho hloleha ha litho le litsamaiso tse 'maloa.

Haeba ho na le lithethefatsi tse ngata tse kenelletseng, Berlition e hloka ho potlakisa sepetlele setsing sa tlhokomelo e matla, moo ho nang le phallo ea mpa, tsamaiso ea litlokotsebe le kalafo e reretsoeng ho tlosa matšoao a bohloko. Berlition ha e na antidote, mme hemodialysis, filtration le hemoperfusion ha e potlakise tlhahiso ea Berlition.

Ts'ebeliso ea Berlition nakong ea kemolo le lactation

Ho sebelisana le lithethefatsi tse ling

Ka lebaka la bokhoni ba ho sebelisana ka lik'hemik'hale le li-ion tsa tšepe, ha ho kgothaletsoe ho nka litokisetso tsa magnesium, iron, kapa calcium ka mor'a ho nka Berlition, kaha li-digestibility tsa bona li tla fokotsoa.Tabeng ena, ho khothalletsoa ho nka Berlition hoseng, le litokisetso tse nang le likhomphutha tsa tšepe thapama kapa ka shoalane. Hoa tšoana le ka lihlahisoa tsa lebese tse nang le calcium e ngata.

Lino tse tahang le joala la ethyl, tse fumanehang mefuteng e fapaneng ea methapo, li fokotsa katleho ea Berlition.

Ho tsepamisa mohopolo ha Berlition ha ho lumellane le tharollo ea tsoekere, fructose, dextrose le Ringer, hobane thioctic acid e baka metsoako e sa sebetseng hantle ea limolek'hule le tsoekere.

Berlition e ntlafatsa phello ea lithethefatsi tsa hypoglycemic le insulin, ka hona, ka ts'ebeliso e le 'ngoe, ho hlokahala hore ho fokotsa litekanyetso tsa bona.

Litla-morao tsa Berlition

Berlition e ka baka litlamorao tse latelang tse tsoang litsong tse fapaneng le litsong tse fapaneng:
1.Ho tsoa tsamaisong ea methapo:

• Phetoho kapa tlolo ea tatso,
• Maqhubu
• Diplopia (maikutlo a pono e habeli).

2.Ho tsoa ho tšilo ea lijo (feela bakeng sa matlapa):

• Nausea
• Ho phomola

3.Ho tsoa tsamaisong ea mali:

• Ponahalo ea mefuta ea pathological ea li-platelet (thrombocytopathy),
• Ho tloaela ho tsoa mali ka lebaka la phetoho ea liplatelete,
• Hemorrhagic rash,
• Spot hemorrhages letlalong kapa mucous membrane (single petechiae),

4.Ka lehlakoreng la metabolism:

• Ho fokotseha ha mahlaseli a tsoekere ea mali,
• Litletlebo tse amanang le tsoekere e tlase ea mali (kizungu, ho ruruha, hlooho e bohloko).

5.Ho tsoa ho sesole sa 'mele:

• Letlalo la letlalo
• Letlalo le makatsang
• Ho thothomela ha anaphylactic (linyeoe tse ikhethileng bathong li tloaetse ho etsa lintho tse itseng).

6.Boitšoaro ba lehae bo hlahang sebakeng sa ente:

• Boikutlo bo tukang sebakeng sa tsamaiso ea tharollo ea Berlition,
• Ho baka bohloko sebakeng sa ente,
• Ho eketseha ha eczema.

7.Tse ling:

• Boikutlo ba ho imeloa kelellong bo hlaha ka lebaka la taolo e potlakileng haholo ea tharollo ka lebaka la keketseho ea khatello ea maqhubu,
• Ho thatafalloa ke ho hema.

Contraindication

Berlition (300 le 600) - li-analogues

• Lipamide - matlapa
• Lipoic acid - matlapa le tharollo ea ente ea methapo ea kutlo,
• Lipothioxone - ho tsepamisa mohopolo ha ho lokisoa tharollo ea tsamaiso ea methapo,
• Neyrolipon - likhapha le ho tsepamisa mohopolo ho lokiseng tharollo bakeng sa tsamaiso ea methapo,
• Oktolipen - likhakeletsi, matlapa le ho tsepamisa mohopolo molemong oa ho lokisa tharollo bakeng sa tsamaiso ea methapo,
• Thiogma - matlapa, tharollo le ho tsepamisa mohopolo bakeng sa ts'ebetso
• Thioctacid 600 T - tharollo bakeng sa tsamaiso ea methapo,
• Thioctacid BV - matlapa,
• Thioctic acid - matlapa,
• Tialepta - matlapa le tharollo ea infusion,
• Thiolipone - tsepamisa maikutlo ha ho etsoa tharollo ea tharollo ea methapo,
• Espa-Lipon - matlapa 'me a tsepamise mohopolo ho lokiseng tharollo bakeng sa tsamaiso ea methapo.

Menahano ea litlatse Meriana e latelang ke:

• Bana ba Bifiform - matlapa a qhekelloang,
• Gastricumel - matlapa a homeopathic,
• Phetello - li-capsules,
• Orfadine - likhechana,
• Kuvan - lipilisi.

Berlition (300 le 600) - litlhahlobo

Litlhahlobo tse mpe tsa Berlition li fokola haholo mme li bakoa haholo ke ho haella ha phello e lebelletsoeng ho tsoa ho eona. Ka mantsoe a mang, batho ba ne ba itšetleha ka phello e le 'ngoe,' me phello e ne e fapane hanyane. Boemong bona, ho na le ho soetseha ho matla ho lithethefatsi, mme batho ba tlohela tlhahlobo e mpe.

Ntle le moo, lingaka tse khomarelang ho boloka ka hloko melao-motheo ea bongaka bo thehiloeng ho bopaki li siea litlhahlobo tse mpe ka Berlition. Kaha ts'ebetso ea bongaka ea Berlition ha e so bonoe, ba lumela hore lithethefatsi ha li na kelello ebile ha li hloke kalafo ea li-neuropathies ho lefu la tsoekere le maemo a mang kapa maloetse. Leha ho bile le ntlafatso e tlisoang ke maemo a batho, lingaka li nka hore Berlition ha e na thuso ebile e siea litlhahlobo tse mpe ka eena.

Berlition kapa Thioctacid?

Thioctacid bakeng sa tsamaiso ea methapo e rekisoa ka tlasa lebitso la khoebo Thioctacid 600 T, 'me e na le 100 mg kapa 600 mg ea ntho e sebetsang ho ampoule e ngoe le e ngoe. Berlition ea ente e fumaneha litekanyetso tsa 300 mg le 600 mg. Ka hona, haeba ho hlokahala, tšebeliso ea lipoic acid ho litekanyetso tse tlase e loketse ho thioctacid. Haeba o hloka ho kenya 600 mg ea lipoic acid, joale o ka khetha sesebelisoa leha e le sefe se thehiloeng ho lithahasello tsa hau. Berlition le Thioctacid ka bobeli li fumaneha ka foromo ea lipilisi, ka hona, haeba ho hlokahala hore u sebelise chelete bakeng sa tsamaiso ea molomo, u ka khetha sethethefatsi leha e le sefe.

Mohlala, matlapa a Thioctacid a fumaneha ka litekanyetso tsa 600 mg, le Berlition - 300 mg, kahoo ea pele e lokela ho nkuoa e le 'ngoe ka letsatsi,' me ea bobeli ka ho latellana, e 'meli. Ho tloha ponong ea ho nolofalletsa, Thioctacid ea rateha, empa haeba motho a sa hlajoe ke lihlong ka lebaka la tlhoko ea ho nka matlapa a mabeli letsatsi le leng le le leng, joale Berlition e mo loketse.

Ntle le moo, ho na le mamello ea lithethefatsi ho latela maemo a 'mele oa motho ka mong. Hona ho bolela hore motho a le mong o mamella Berlition hamolemo, mme e mong - Thioctacid. Boemong bo joalo, hoa hlokahala ho khetha moriana o mamelloang hamolemo ebile o sa bake litla-morao. Empa sena se ka khethoa feela teko ka ho leka ho sebelisa lithethefatsi tse fapaneng.

Leha ho le joalo, haeba matšoao a kliniki a le matla haholo kapa matlapa a sa thusa, ho khothalletsoa ho fana ka lithethefatsi tse nang le alpha-lipoic acid kahare. Boemong bo joalo, ho hlokahala ho sebelisa Berlition ka mokhoa oa ho tsepamisa mohopolo bakeng sa ho hlophisoa ha tharollo bakeng sa tsamaiso ea methapo, kapa Thioctacid 600 T.

Berlition (matlapa, ampoules, 300 le 600) - theko

Hajoale, likhoebong tsa litoropo tsa Russia, litšenyehelo tsa Berlition li ka tsela e latelang:

• Matlapa a Berlition 300 mg 30 likotoana - 720 - 850 li-ruble,
• Berlition tsepamisa kelello 300 mg (12 ml) li-ampoules tse 5 - 510 - 721 li-ruble,
• Berlition tsepamisa kelello 600 mg (24 ml) li-ampoules tse 5 - 824 - 956 li-ruble.

Ho reka kae?

Sehlopha sa Berlin-Chemie AG / Menarini, se hlahisitsoeng ke Iyegeksal Pharma GmbH (Jeremane), Yenageksal Pharma GmbH (Jeremane), Ever Pharma Iye GmbH / Berlin-Chemie AG (Jeremane)

Ketso ea pharmacological

Hepatoprotective, detoxification, hypocholesterolemic, lipid-lowing, antioxidant.

Ke coenzyme ea oxidative decarboxylation ea pyruvic acid le alpha-keto acid, normalize matla, carbohydrate le lipid metabolism, mme e laola metabolism ea cholesterol.

E ntlafatsa ts'ebetso ea sebete, e fokotsa phello e senya ea chefo ea emong le e tsoang ho eona.

Kamora ho tsamaisoa ka molomo, e kenella ka potlako le ka botlalo, khatello e kholo e fihlelloa kamora metsotso e 50.

Bioavailability e batla e le 30%.

E matlafatsa le ho kopanya sebete seolong.

E khahliloe ke liphio ka mokhoa oa metabolites (80-90%).

Bophelo ba halofo ke metsotso e 20-50.

Litla-morao tsa Berlition

Ts'oaetso ea "metabolism" ea "glucose metabolism" (hypoglycemia), lintho tse kulisang (ho kenyelletsa ho makala ha anaphylactic), le ts'ebetso ea ho lieha kapa ho lieha ho phefumoloha, khatello e matla ea intracranial, letsoalo, diplopia, hemorrhages ea letlalo le li-membrane tsa mucous.

Matšoao a ho sebelisoa

Coronary atherosulinosis (thibelo le kalafo), mafu a sebete (lefu la Botkin le bonolo ho honyela ho lekana, cirrhosis), polyneuropathy (lefu la tsoekere, lekhoba la joala), chefo e boima ea tšepe le lino tse ling.

Polelo ea lihlopha tsa nosological

Sehlooho sa ICD-10	Li-syndms tsa maloetse ho ea ka ICD-10
G62.1 Alcoholic polyneuropathy	Alcoholic polyneuritis
	Alcoholic polyneuropathy
G63.2 Diabetesic polyneuropathy (E10-E14 + e nang le nomoro e tloaelehileng ea bone. 4)	Ho opeloa ke lefu la tsoekere le lefu la tsoekere
	Bohloko ho lefu la tsoekere
	Bohloko ho lefu la tsoekere la polyneuropathy
	Lefu la tsoekere la polyneuropathy
	Lefu la tsoekere
	Leqeba la lesapo la tsoekere la sethoathoa
	Lefu la tsoekere
	Lefu la tsoekere la polyneuropathy
	Diabetesic Polyneuritis
	Lefu la tsoekere
	Peripheral Diabetesic Polyneuropathy
	Lefu la tsoekere la polyneuropathy
	Sensory-motor diabetesic polyneuropathy
K71 Ho lemala ha chefo	Matla a lithethefatsi ho sebete
	Tšusumetso ea chefo leseleng
	Hepatitis ea bongaka
	Ho hepatitis e chefo
	Hepatotoxic litlamorao tsa lithethefatsi
	Tšenyo ea lithethefatsi ho sebete
	Hepatitis ea kalafo
	Tšenyo ea lithethefatsi ho sebete
	Drug hepatitis
	Drug hepatitis
	Ho senyeha ha sebete sa ts'ebetso ea etiology e nang le chefo
	Ho hepatitis e chefo
	Tšenyo ea sebete e nang le chefo
	Ho hepatitis e chefo
	Lefu le nang le chefo ea sebete
	Tšenyo ea sebete e nang le chefo
K76.0 Ho fokola hoa mafura a sebete, eseng libakeng tse ling	Mafura a hepatosis
	Mafura a sebete sa 'mele
	Mafura a sebete
	Sebete se mafura
	Sebete se mafura
	Sebete se mafura
	Mafura a hepatosis
	Lipidosis
	Mathata a amanang le metabolism ea lipid ea sebete
	Steatohepatitis e senang joala
	Atlese e tsoang ka bongata ea 'mala oa sebete
	Steatohepatitis
	Steatosis
	Steatosis

Berlition 600 - sesebelisoa se amang ts'ebetso ea tšilo ea lijo le lits'ebetso tsa metabolic.
Thioctic acid ke ntho ea tlhaho e tšoanang ka ketso ea livithamini, e sebetsang joaloka coenzyme mme e nka karolo ho oxidative decarboxylation ea acid-keto acid. Ka lebaka la hyperglycemia e bang teng ka har'a lefu la tsoekere, "glucose" e kenelletse liprotheineng tsa methapo ea mali le ho etsoa ha seo ho thoeng ke "lihlahisoa tsa" glycolysis tse potlakileng ". Ts'ebetso ena e lebisa ho fokotseha ha phallo ea mali ea endoneural le hyponeia / ischemia, e leng eona e lebisang ho thehoeng ha li-radicals tsa mahala tse nang le oksijene tse senya methapo ea kutlo. Ho fokotseha hoa boemo ba li-antioxidants, joalo ka glutathione, methapong ea methapo le hona ho hlokometsoe.

Tekanyetso le tsamaiso

Tekanyetso ea letsatsi le letsatsi ke 300-600 mg (ampoules ea 1-2). Li-ampoules tse peli tsa lithethefatsi (12-24 ml ea tharollo) li hlapolotsoe ka 250 ml ea tharollo ea chloride ea 0,9% mme e kenngoa kahare ka nako e ka bang metsotso e 30.

Qalong ea ts'ebetso ea kalafo, moriana o fanoa ka libeke tse 2 ho isa ho tse 2.

Kamora moo, o ka tsoela pele ho nka acid e mashome a mararo a motso o mong ka nako ea lethal la 300-600 mg / ka letsatsi.

Tšebeliso ea lithethefatsi Berlition

Lefu la tsoekere le joala bo tahang.
Lithethefatsi Berlition 300 likotloana, Berlition 300 molomo - ka mokhoa oa matlapa a koahetsoeng, nka likhabapo tse 2 kahare hang ka letsatsi, li-capsule tse 600 tsa Berlition - 1 capsule e le 1 ka letsatsi metsotso e 30 pele ho lijo tsa pele.
Maemong a tebileng a lefu lena, tsamaiso e kopaneng ea moriana (iv le molomo) e sebelisoa nakong ea libeke tsa pele tsa kalafo tsa 1: hoseng iv ente ea 24 ml / ka letsatsi Berlition 600 U ka ka sebopeho sa ho tsepamisa mohopolo ho lokiseng tharollo ea infusion kapa 12-24 ml ea tharollo drug Berlition 300 IU ka mokhoa oa ho tsepamisa mohopolo ho lokiseng tharollo ea infusion 'me ka shoalane - nka moriana o le ka har'a likhabapo kapa matlapa Berlition 300 kapa 600 mg.
Bakeng sa dilution ea lithethefatsi Berlition 300 kapa 600 IU sebelisa feela 0,9% sodium chloride tharollo. Likateng tsa ampoule li hlapolotsoe ka 250 ml ea tharollo ena 'me li ente iv bakeng sa bonyane metsotso e 30. Tharollo ea lithethefatsi e tlameha ho sireletsoa ho pepesetsoa ke khanya ea letsatsi (mohlala, phuthela botlolo ka foil ea aluminium). Haeba boemo bona bo kopana, tharollo e hlapollotsoeng e ka bolokoa lihora tse 6. Bakeng sa kalafo e tsoelang pele, 300-600 mg ea α-lipoic acid e sebelisoa ka mokhoa oa litafole kapa li-capsule tsa Berlition 300 kapa 600 mg. Nako ea kalafo ke bonyane likhoeli tse peli, haeba ho hlokahala, e ka etsoa makhetlo a 2 ka selemo.
V / m kena Likarolo tse 300 tsa Berlition hoa khoneha ka ente e ka tekanyetso e sa feteng 2 ml, sebaka sa ente ea methapo ea methapo se lokela ho fetoloa khafetsa. Nako ea kalafo ke libeke tse 2-4. Joalo ka kalafo e tšehetsang, tsamaiso ea molomo e bontšoa. Berlition 300 ka molomo Matlapa a 1-2 ka letsatsi ka likhoeli tse 1-2.
Lefu la sebete. Lithethefatsi li laetsoe ho latela morero o kaholimo ho lethal dose ea 600-1200 mg ea α-lipoic acid ka letsatsi, ho latela botebo ba boemo le litekanyetso tsa laboratori tsa boemo bo sebetsang ba sebete sa mokuli.

Litšebelisano tsa Lithethefatsi

α-lipoic acid e etsa metsoako e rarahaneng le tšepe (ka mohlala, le cosplatin), ka hona, ts'ebeliso ea eona e ts'oanang le lisplatin, tšepe, magnesium le lihlahisoa tsa lebese, ka lebaka la litaba tsa calcium ho tsona, ha li khothalletsoe. Cisplatin ha ea lokela ho laeloa ka nako e ts'oanang le ts'ebeliso ea Berlition ka lebaka la ho fokotseha ha ts'ebetso ea eona tlasa ts'usumetso ea α-lipoic acid.
α-Lipoic acid e khona ho theha metsoako e rarahaneng e sa sebetseng hantle le tsoekere e fumanehang ho tharollo ea infusion, ka hona, lithethefatsi ha li lumellane le fructose, tsoekere, joalo-joalo le lithethefatsi tse tsejoang ho kena. ha o sebetsana le li-SH-lihlopha kapa marokho a qhalanang.

Melemo ea pharmacological

Pharadodynamics Sesebelisoa sa mantlha sa motsoako ke antioxidant ea tlhaho e kopanyang li-radicals tsa mahala. Acid e hlahisoa ke 'mele ka lebaka la litla-morao tsa oxidative ho li-acid tsa α-keto.

Ela hloko! Litlhahlobo tsa lingaka li bonts'a hore moriana o na le phello e molemo ho theoleng tsoekere ea mali, ho eketsa litheko tsa glycogen ea sebete le ho hlola ho hanyetsa insulin.

Ka thepa ea bona ea biochemical, matlapa a Berlition 300 le 600 a haufi le livithamini tsa B.

1. Nka karolo ho tloaelehileng ea carbohydrate le lipid metabolism.
2. Ntlafatsa ts'ebetso ea sebete, hlohlelletsa metabolism ea cholesterol.
3. Li na le hypoglycemic, hepatoprotective, hypocholesterolemic, hypolipidemic effect.

Ts'ebeliso ea Berlition 300 le 600 ho infusions bakeng sa ente ea intravenous e ka fokotsa botebo ba karabelo e fosahetseng.

Mofumahali Matlapa a Berlition 300 le 600, kapa, lintho tsa ona tse sebetsang, a khona ho "feta pele" ka har'a sebete. Thioctic acid le likarolo tsa eona li batla li lekantsoe ka botlalo (80-90%) ke liphio.

Tharollo ea ente Berlition. Nako ea ho fihlela khatello e phahameng 'meleng ka tsamaiso ea methapo e 10 ke metsotso e 10-11. Sebaka se tlas'a curveutical curve (nako ea mahloriso) ke 5 μg h / ml. Khatello e kholo ke 25-38 mcg / ml.

Matlapa a Berlition bakeng sa tsamaiso ea molomo a qhala kapele 'me a kenelle ka botlalo mokhoeng oa ho silila. Ha e nkoa ka lijo, adsorption ea fokotseha. Khatello e phahameng ea lithethefatsi e fihlella ka mor'a metsotso e 40-60. Bioavailability ke 30%.

Bophelo ba halofo ke metsotso e 20-50. Tlhahiso ea plasma ka botlalo ke 10-15 ml / min.

Likarolo tse ling tsa lithethefatsi

Litlhahlobo tsa lingaka le bakuli ka Berlition li ntle haholo, empa joalo ka lithethefatsi tse ling, e na le litšobotsi tsa eona. Nakong ea kalafo, bakuli ba lokela ho hana ho itlopa joala.

Litsebi tsa lefu la tsoekere li hloka ho hlahlojoa khafetsa maemong a tsoekere ea plasma. Sena ke sa bohlokoa haholo qalong ea kalafo. Ka linako tse ling ho ka hlokahala ho fokotsa tekanyetso ea lithethefatsi tsa insulin kapa hypoglycemic tse nkuoeng ke bakuli ka hare. Kahoo, kotsi ea hypoglycemia e thibetsoe.

Tharollo ea ente ea Berlition 300 kapa 600 e lokela ho sireletsoa ho mahlaseli a UV. Sena se etsoa ka ho thatela botlolo ka foil ea aluminium. Tharollo e sirelelitsoeng ka tsela ena e ka bolokoa lihora tse 7.

Litlamorao

Hangata, ha li etsahale, empa maemong a sa tloaelehang, ka mor'a ho thella ka tharollo, ho tsitsipana, hemorrhages e nyane ho li-membrane tsa mucous le letlalo, hemorrhagic rash, thrombocytosis li khonahala.Ka tsamaiso e potlakileng haholo, ho na le monyetla oa khatello ea maikutlo le ho hema ka thata.

Litlhahlobo tse tsoang ho bakuli le lingaka li re matšoao ana kaofela a tsamaea ntle le ts'ebetso.

Ho na le karabelo ea lehae e hlahang sebakeng sa ente. Sena e kanna ea eba urticaria kapa ponahatso e 'ngoe ea ho kula, ho fihlela mokhatlong oa anaphylactic. Nts'etsopele ea hypoglycemia, e kanna ea hlahisoa ke ntlafatso ea ho monya tsoekere, ha e qheleloe ka thoko.

Matlapa a Berlition hangata a mamelloa ntle le litlamorao tse mpe. Empa ka linako tse ling mathata a latelang a ka etsahala:

Ho sebelisana le meriana e meng

In vitro Berlition e kopana le metsoako ea tšepe. Mohlala, cisplatin e ka nahanoa. Ka hona, ho sebelisoa ka nako e le 'ngoe le cisplatin ho fokotsa phello ea eona.

Empa phello ea lithethefatsi tsa hypoglycemic tsa molomo le insulin, Berlition 300 kapa 600, ho fapana le hoo, ea matlafala. Ethanol, e fumanoang lino tse tahang, e fokotsa ts'ebetso ea kalafo (litekolo tsa bala).

Motsoako o sebetsang oa Berlition, ha o sebetsana le tsoekere, o etsa metsoako e ke keng ea qhibiliha. Ka mor'a moo, tharollo ea thioctic acid e ke ke ea kopana le infusion ea dextrose, Ringer le tharollo tse ling tse tšoanang.

Haeba Berlition 300, matlapa a 600 a ne a nkuoe hoseng, o ka sebelisa lihlahisoa tsa lebese, magnesium le litokisetso tsa tšepe feela ka mor'a lijo tsa motšeare kapa ka shoalane. Mabapi le lihlahisoa tsa lebese, sena se bakoa ke taba ea hore li na le calcium e ngata.

Ho na le litlolo tse teng

• Nako ea kemaro le kanyeso. Le ha litlamorao tse mpe tsa moriana li sa netefatsoa, ​​kaha ha ho na litlhahlobo le lithuto tsa Morero o joalo.
• Kutloisiso e phahameng ho likarolo tsa Berlition.
• Moriana ha o ngoletsoe bana (ha ho na litlhahlobo mabapi le polokeho le katleho).

Ho boloka, phomolo, ho paka

Setlhare ke sa lethathamo la B. E lokela ho bolokwa ka mocheso o sa feteng 25 ° C, sebakeng se lefifi se sa fumaneheng ho bana.

Nako ea ts'ebeliso e latela mofuta oa tokollo:

• tharollo ea ente - lilemo tse 3,
• lipilisi - lilemo tse 2.

Berlition e lokolloa feela ka lengolo la ngaka. Tharollo ea ente e fumaneha ka ampoules e lefifi ea 25 mg / ml. Mabokose a likarete tsa (likarete) a na le li-ampoules tse 5. Litaelo tsa tšebeliso ke tsena.

Matlapa a Berlition a koahetsoe 'me a pakiloe ka likotoana tse 10 ka marang-rang a entsoe ka thepa e tsoakiloeng ea PVC kapa foil ea aluminium. Phutheloana ea karete e na le lithupa tse 3 tse joalo le litaelo tsa ho li sebelisa.

Tlhaloso ea litlhare ea bongaka ba bongaka ba bongaka ba Jeremane Berlin Chemi ke ntho e fetang feela thioctic (alpha-lipoic) acid - antioxidant ea endo native e sebelisang li-radicals tsa mahala ebile e sebelisoa ho tsa bongaka e le hepatoprotector. Ho ea ka mohopolo oa sejoale-joale, ntho ena ke ea livithamini ("Vitamin N"), mesebetsi ea tlhaho eo e amanang le ho nka karolo ha eona molemong oa oxidative decarboxylation ea alpha-keto acid. Boteng ba lihlopha tsa sulfhydryl, tse ikemiselitseng ho "etsa likhoele" bohle ba nang le bomalimabe ba ho ba haufi le li-radicals tse mpe tse kotsi, li fa thepa ea antioxidant molek'huleng ea thioctic acid. Sena se thusa ho hlaphoheloa ha limolek'hule tsa protheine tse senyehileng ke khatello ea oxidative. Kahoo, thioctic acid e na le phello e ntle ho metabolism ea liprotheine, lik'habohaedreite, cholesterol mme e sebetsa e le detoxifier ha ho ka etsahala hore e chefo ka lipilisi tsa ho robala le matsoai a tšepe e boima. Liphetoho tsa bohlokoa ka ho fetisisa tsa tlhaho ea thioctic acid li kenyelletsa: ts'ebetso ea phetisetso ea tsoekere ea transmembrane le ts'ebetso e ts'oanang ea lits'ebetso tsa eona tsa oxidation, khatello ea methapo ea oxidation, phello ea antioxidant, phokotso ea likhahla tsa mafura a mali, thibelo ea mekhoa ea ho petsoha hoa mafura, ho fokotseha hoa khatello ea cholesterol maling. mali, eketseha ho hanyetsa lisele ho tlala ea oksijene, ho eketsa phello ea anti-inflammatory ea corticosteroids, choleretic, spasm litlamorao tsa lipolotiki le maemo a morao-rao.

Ka lebaka lena, thioctic acid (berlition) e sebelisoa haholo bakeng sa mafu a sebete, khatello ea mali ea methapo, lefu la atherosclerosis le lefu la tsoekere. Ha u sebelisa litlatse e le hepatoprotector, tekanyetso le bolelele ba thupelo ea pharmacotherapeutic bo bohlokoa haholo. Liteko tsa bongaka tse entsoeng tse fetang mashome a mane a lilemo li bonts'itse hore lethalinyana la 30 mg ha le a thusa kalafong ea lefu la sebete la sebete le lefu la sebete, empa ho eketseha ha lona ka makhetlo a leshome le ho feta ka likhoeli tse tšeletseng ho hlile ho ntlafatsa biochemistry ea hepatic. Haeba o kopanya mokhoa oa molomo le ente ea monokotšoai (le lithethefatsi li fumaneha ka mokhoa oa litafole ebe o tsepamisa mohopolo ho lokiseng tharollo ea infusion), sephetho se lakatsehang se ka fihlella kapele.

Kahoo, ho ka boleloa hore berlition ka lebaka la phello ea eona ea antioxidant le phello ea lipotropic ke e 'ngoe ea lithethefatsi tsa bohlokoa bakeng sa kalafo ea liso tsa sebete, ho kenyeletsa cirrhosis, hepatitis, cholecystitis e sa foleng. Setlhare se ka sebelisoa hape ho tloaelo ea pelo ho bakuli ba nang le lefu la pelo le methapo, lefu la pelo le methapo. Litlamorao tse fapaneng le Berlition li fumaneha seoelo ebile ha se bothata bo sa reroang bakeng sa tšebeliso ea lithethefatsi hape.

Thutela-litso

Asiti ea Thioctic (alpha-lipoic) ke antio-antioidant ea nako e telele (e tlamisang li-radicals tsa mahala) le litlamorao tse sa tobang. Ke coenzyme ea decarboxylation ea alpha-keto acid. E thusa ho fokotsa khatello ea "glucose" e maling le ho eketsa bongata ba glycogen sebeteng, e boetse e fokotsa ho hanyetsa insulin, e kenya letsoho taolong ea "carbohydrate" le metabolid metabolism, e hlohlelletsang phapanyetsano ea cholesterol. Ka lebaka la thepa ea eona ea antioxidant, thioctic acid e sireletsa liseleng hore li se ke tsa senyeha ke lihlahisoa tsa tsona tse bolileng, e fokotsa sebopeho sa lihlahisoa tse tsoelang pele tsa glycosylation tsa liprotheine liseleng tsa methapo ho lefu la tsoekere la tsoekere, le ntlafatsa methapo ea mali le tsamaiso ea mali a sa feleng, 'me ea eketsa litaba tsa mmele tsa glutathione antioxidant. Ho thusa ho fokotsa bongata ba "glucose" plasma ea mali, e ama metabolism e 'ngoe ea tsoekere ho tsoekere ea tsoekere, e fokotsa ho bokellana ha methapo ea methapo ea methapo ka methapo ea methapo, mme ka hona e fokotsa ho ruruha ha lisele tsa methapo. Ka lebaka la ho nka karolo ho metabolism ea mafura, thioctic acid e eketsa biosynthesis ea phospholipids, haholo phosphoinositides, e ntlafatsang sebopeho se senyehileng sa li-membrane tsa lisele, le ho fokotsa metabolism ea methapo le methapo ea kutlo. Thioctic acid e tlosa litlamorao tse chefo tsa metabolites ea joala (acetaldehyde, pyruvic acid), e fokotsa sebopeho se fetelletseng sa limolek'hule tsa radicals tsa oksijene e sa lefelloeng, e fokotsa endoneural hypoxia le ischemia, e fokolisa lipontšo tsa polyneuropathy ka mokhoa oa paresthesia, sensation e tukang, bohloko le ho tepella maikutlo. Kahoo, thioctic acid e na le antioxidant, neurotrophic effect, e ntlafatsa metabolism ea lipid.

Tšebeliso ea thioctic acid ka mokhoa oa letsoai la ethylenediamine e ka fokotsa botebo ba litlamorao tse ka bang teng.

Maemo a polokelo ea lithethefatsi Berlition

Ka mocheso o sa feteng 30 ° C. Bakeng sa ho sireletsa se kahare ketsong ea khanya, li-ampoules li lokela ho bolokoa ka lebokoseng la karete. Tharollo e lokiselitsoeng ea infusion e loketse tšebeliso ea lihora tse 6, ha feela e sirelelitsoe leseli.

Lethathamo la meriana moo u ka rekang Berlition:

Sengoliloeng sena sa bongaka, u ka fumana lithethefatsi Berlition. Litaelo tsa tšebeliso li tla hlalosa hore na o ka sebelisa liente kapa matlapa afe, hore na moriana o thusa eng, ho na le matšoao afe a sebelisoang, contraindication le litlamorao. Tlhahiso e hlahisa sebopeho sa moriana le sebopeho sa ona.

Sehloohong, lingaka le bareki ba ka siea litlhahlobo tsa 'nete ka Berlition, moo u ka fumanang hore na moriana o thusitse kalafong ea lefu la hepatitis, cirrhosis, lino tse nang le tahi le lefu la tsoekere ho batho ba baholo le bana, eo e ntseng e laetsoe. Litaelo tsa lenane la litlhaloso tsa Berlition, litheko tsa sethethefatsi sena litlhare, hammoho le ts'ebeliso ea eona nakong ea kemolo.

Sesebelisoa se laolang metabolism 'meleng oa motho ke Berlition. Litaelo tsa tšebeliso li bonts'a hore matlapa kapa li-capsules tsa 300 mg, liente ka ampoules ea li-injection li thusa ka mathata a sebete.

Litlamorao

Tšebeliso ea Berlition e ka baka litlamorao tse latelang:

• Litla-morao: Ho hlohlona, ​​lekhopho la letlalo, urticaria, eczema.
• Ho tsoa pampiring ea ka mpeng: mathata a dyspeptic, ho nyekeloa le pelo, ho hlatsa, phetoho, tatso, ho hloka toka.
• Ho tloha lehlakoreng la ts'ebetso ea methapo e bohareng: maikutlo a boima hloohong, diplopia, litsitsipano (kamora taolo e potlakileng ea taolo).
• Ho tsoa ho CCC: tachycardia (kamora ts'ebetso e potlakileng ea tsamaiso), hyperemia ea sefahleho le 'mele o holimo, bohloko le ho ikutloa o tiile sefubeng.
• Maemong a sa tloaelehang, ho ts'oaroa ha anaphylactic ho ka hlaha.

Matšoao a hypoglycemia, hlooho e opang, ho fufuleloa ho feteletseng, ho tsekela le ho senyeha ha pono le tsona li ka hlaha. Ho phefumoloha hanyenyane, ho phefumoloha, le thrombocytopenia ka linako tse ling ho bonoa. Qalong ea kalafo ho bakuli ba nang le polyneuropathy, paresthesia e nang le maikutlo a hoosebumps e ka eketseha.

Li-analoggs tsa lithethefatsi Berlition

Sebopeho se etsa qeto ea li-analogues:

1. Lipothioxone.
2. Thioctic asiti.
3. Thioctacid 600.
4. Lipoic acid.
5. Neuroleipone.
6. Tiolepta.
7. Lipamide
8. Oktolipen.
9. Thiolipone.
10. Alpha Lipoic Acid
11. Tiogamma.
12. Espa Lipon.

Ho sehlopha sa hepatoprotectors ho kenyelletsa analogue:

1. Antraliv.
2. Silymarin.
3. Ursor Rompharm.
4. Ursodex.
5. Phospholipids tsa bohlokoa.
6. Silymar.
7. Tykveol.
8. Bongjigar.
9. Thioctic asiti.
10. Hepabos.
11. Gepabene.
12. Berlition 300.
13. Erbisol.
14. Essliver.
15. Sibektan.
16. Ornicketil.
17. Progepar.
18. Lebese le bolaeang.
19. 52. 52.
20. Urso 100.
21. Ursosan.
22. Gepa Merz.
23. Urdox.
24. Rezalyut Pro.
25. Choludexan.
26. Thiolipone.
27. Metrop.
28. Eslidine.
29. Ursofalk.
30. Thiotriazolinum.
31. Phosphogliv.
32. Silegon.
33. Berlition 600.
34. Essentiale N.
35. Phosphoncial.
36. Silibinin.
37. Sirepar.
38. Cavehol.
39. Ursodeoxycholic acid.
40. Ursoliv.
41. Brentsiale forte.
42. Livodex.
43. Ursodez.
44. Methionine.
45. Legalon.
46. Vitanorm.

Maemo a phomolo le theko

Litšenyehelo tse tloaelehileng tsa Berlition (matlapa a 300 mg No. 30) Moscow ke li-ruble tse 800. Ampoules 600 mg 24 likhomphutha. theko li-ruble tse 916. E fanoe ke lengolo la ngaka.

Matlapa a bolokiloe ka likamoreng tse ommeng ka mocheso oa 15-25 C. Bophelo ba sekhele - lilemo tse 2. Li-capsule li bolokiloe sebakeng se ommeng le se lefifi ka mocheso o sa feteng 30 C. Bophelo ba sethala sa li-capsule tsa Berlition ke lilemo tse 300 - 3, 'me li-capsule li le lilemo tse 600 ho isa ho tse 2,5.

Lithethefatsi ke moemeli oa sehlopha sa hepatoprotectors - lithethefatsi tse eketsang ho hanyetsa ha lisele tsa sebete ho litlamorao le ho ntlafatsa ts'ebetso ea tsona ka botlalo. Likarolo tse sebetsang tsa moriana li kenyelletsa taolong ea metabolism ea lipid le carbohydrate le ho bonts'a thepa ea detoxifying. Litlamorao tsena li bakoa ke tšebeliso ea lithethefatsi ho mafu a sebete le li-pathologies tse ling tse amang setho sena.

Berlition ea lithethefatsi le ts'ebeliso ea eona

Ho latela litekanyetso tsa motsoako o sebetsang, lithethefatsi li ka khethoa "Berlition 300" kapa "Berlition 600". Foromo ea pele e na le 300 mg ea ntho e sebetsang, 'me ea bobeli - 600 mg. Ts'oarello ea eona e lula e ts'oana 'me ke 25 mg / ml. Ka lebaka lena, setlhare sena ka mokhoa oa tharollo ea infusion se fumaneha ka bongata ba 12 ml le 24 ml. Matlapa le likhakeletsi li ka ba le litekanyetso tse fapaneng le palo ea likotoana tseo sephutheloana se nang le tsona. E tloaelehileng mefuteng eohle ke karolo e tšoanang e sebetsang.

Sebopeho le mofuta oa tokollo

Karolo e sebetsang ea motsoako ona ke alpha lipoic acid (thioctic, lipoic, vithamini N), e leng ntho e kang vithamine.E bohlokoa bakeng sa oxidative decarboxylation ea alpha-keto acid. Sebopeho se seng le se seng sa tokollo se na le likarolo tsa sona tse thusang. Moetso o hlalosoa ka mokhoa o qaqileng haholoanyane tafoleng:

Tekanyo ea motsoako o sebetsang - thioctic acid

Tsepamisa maikutlo tse sebelisoang bakeng sa marotholi

300 mg kapa 600 mg

Ethylene diamine, propylene glycol, metsi a ente.

Tharollo e hlakileng e nang le "tint" e putsoa e tala, li-ampoule tse 5, 10 kapa 20, tse rekisitsoeng ka har'a li-trayard tsa karete (300 mg), kapa li-ampoules tse 5, tse kentsoeng lipolasetiking.

300 mg kapa 600 mg

Titanium dioxide, mafura a tiileng, tharollo ea sorbitol, gelatin, glycerin, triglycerides, amaranth, triglycerides e mahareng.

Phofo ka khetla e bonolo ea gelatin, e pakiloeng ka marang-rang.

Povidone, lactose monohydrate, colloidal silicon diabolic, MCC, sodium-croscarmellose sodium, le magnesium stearate.

E pota-potile sebopeho, 'mala o mosehla, o koahetsoeng ke filimi, biconvex, o kotsing e ka lehlakoreng le leng, o na le karolo e boreleli, e sa lekanang sebakeng sa sefapano.

Matlapa a Berlition

Moriana ka mokhoa oa matlapa a nooa ka molomo ka botlalo. Ho molemo ho etsa sena hoseng pele ho lijo tsa hoseng, kaha ho ja ho ama ho entoa hoa karolo e sebetsang. Bakeng sa letsatsi, o hloka ho nka 600 mg ka nako, i.e. Matlapa a 2 hang. Nako ea thupelo e behiloe ho latela maemo a mokuli le matšoao a hae. Hangata matlapa a sebelisetsoa ho phekola atherosclerosis, chefo le lefu la sebete. Litekanyetso li ikemiselitse ho nahanela lefu lena.

• kalafo ea lefu la tsoekere polyneuropathy - 600 mg ka letsatsi (i.e. matlapa a 2 ka nako),
• kalafo ea li-pathologies tsa sebete - 600-1200 mg (matlapa a 2-4) letsatsi le letsatsi.

Li-ampoules tsa Berlition

Tharollo e lokiselitsoe ho tsoa ho moriana o ka li-ampoules molemong oa tsamaiso ea methapo ka ho kenella (li-droppers). Ho kenella ka har'a dikahare tsa thioctic acid ea 300 mg le 600 mg ho sebelisoa ho latela litaelo tse tšoanang. Monyetla oa infusions holim'a lipilisi ke bohato bo potlakileng. Mokhoa ona oa ho sebelisa moriana o bontšoa matšoao a matla a kliniki.

Ho lokisa sehlahisoa, 1 ampoule ea 12 ml kapa 24 ml e hlapolotsoe ka 250 ml ea saline ea mmele. Morero oa tšebeliso ea ona kalafong ea li-neuropathies:

• Nako e le ngoe letsatsi le leng le le leng bakeng sa libeke tsa 2-4, li-droppers li beoa tse nang le 300 mg kapa 600 mg ea thioctic acid,
• ebe ba fetohela ho litekanyetso tsa tlhokomelo le ho nka lipilisi tsa 300 mg letsatsi le letsatsi.

Hoa hlokahala ho lokisa Berlition bakeng sa infusions hang-hang pele ho ts'ebetso. Lebaka ke hore e lahleheloa ke thepa ea eona kapele. Kamora ho itokisa, tharollo e tlameha ho sireletsoa ho khanya ea letsatsi ka lebaka la khanya ea eona ea khanya. Ho etsa sena, setshelo se nang le eona se phuthetsoe ka pampiri e teteaneng kapa foil. Metsoako ea rona e kenelletseng e bolokiloe nako e sa feteng lihora tse 6, ha feela e le sebakeng se ke keng sa fumaneha ka khanya ea letsatsi.

Litaelo tsa ho sebelisa likhapha li tšoana le tsa matlapa. Li nkoa ka molomo ntle le ho hlafuna kapa hona ho tlola. Motsoako oa letsatsi le letsatsi ke 600 mg, i.e. 1 capsule Hoa hlokahala ho e sebelisa ka sekhahla se lekaneng sa metsi. Ho molemo ho etsa sena hoseng halofo ea hora pele u ja. Haeba litekanyetso tsa motsoako oa li-capsules li 300 mg, ka nako eo o hloka ho nka likotoana tse 2 hang.

Litekanyetso tsa bohlokoa

Sehlooho:	PUSELETSO 600
Khoutu ea ATX:	A16AX01 -

Ntle le moo: propylene glycol, ethylene diamine, metsi a ente.

E le 'ngoe capsule e ka kenyelletsa 300 mg kapa 600 mg thioctic asiti. Ntle le moo: mafura a tiileng, ketane ea triglycerides, ligatin, tharollo ea sorbitol, glycerin, amaranth, titanium dioxide.

E le 'ngoe Letlapa e kenyelletsa 300 mg thioctic asiti. Ntle le moo: magnesium stearate, lactose monohydrate, croscarmellose sodium, MCC, colloidal silicon dioxide, povidone, opadry e putsoa OY-S-22898 (joalo ka khetla).

Bakeng sa mefuta eohle ea litekanyetso tsa moriana

• tlolo ea molao / phetoho ka tatso,
• fokotseha ha plasma dikaharetsoekere (ka lebaka la ntlafatso ea monko oa eona),
• matšoao hypoglycemiaho kenyelletsa mosebetsi o sa bonahaleng oa pono,
• liponahatsoho kenyelletsa letlalo makhopho/, urticaria rash (), (Maemong a ikhethileng).

Ho kenyelletsa mefuta ea lithethefatsi tsa botsoali

• diplopia,
• ho chesa sebakeng sa ente,
• cramps,
• thrombocytopathy,
• letsolo
• ho hema hanyane le eketsa (e hlokometsoe maemong a taolo ea iv e potlakileng le ho feta ka mokhoa o ikemetseng).

Berlition, litaelo tsa tšebeliso (Mokhoa le litekanyetso)

Litaelo tsa semmuso tsa ts'ebeliso ea Berlition 300 li ts'oana le litaelo tsa ho sebelisoa ha Berlition 600 bakeng sa mefuta eohle ea litekanyetso tsa moriana ona (tharollo ea ente, likhakeletsi, matlapa).

Motsoako Berlition o reretsoeng ho hlophisoa ha infusions o laetsoe ka tekanyetso ea letsatsi le letsatsi ea 300-600 mg, e fanoang kahare letsatsi le letsatsi ka sekhahla bonyane metsotso e 30, bakeng sa libeke tse 2-4. Hang-hang pele ho ts'oaetso, tharollo ea lithethefatsi e lokisoa ka ho kopanya se kahare ho ampoule e le 'ngoe ea 300 mg (12 ml) kapa 600 mg (24 ml) le 250 ml ente (0,9%).

Mabapi le photosensitivity ea tharollo ea infusion e lokiselitsoeng, e tlameha ho sireletsoa ho pepesetsoa leseli, mohlala, e koaheletsoeng ka foil ea aluminium. Ka foromo ena, tharollo e ka boloka thepa ea eona nako e ka bang lihora tse 6.

Kamora libeke tse 2-4 tsa kalafo ka tšebeliso ea infusions, ba fetoha kalafo ka ts'ebeliso ea mefuta ea litekanyetso tsa moriana. Li-capsloma tsa Berlition kapa litafole li beoa ka tekanyetso ea tlhokomelo ea letsatsi le letsatsi ea 300-600 mg mme li nkuoa ka mpeng e se nang letho ka nako e ka bang halofo ea hora pele ho lijo, li nooa ka 100-200 ml ea metsi.

Nako ea ts'ebetso ea ho kenella le ea kalafo ea molomo, hammoho le monyetla oa boits'oaro ba bona bo phetoang, e khethoa ke ngaka e le 'ngoe ka bo eona.

Litaelo tsa ho sebelisoa ha Berlition: mokhoa le litekanyetso

Hangata moriana o nooa hang ka letsatsi, hoseng, halofo ea hora pele ho lijo tsa hoseng. Matlapa a Berlition a ke ke a hlafuna le ho sithabetsoa. Tekanyetso ea letsatsi le letsatsi bakeng sa batho ba baholo ke 600 mg (matlapa a mabeli).

Setlhare ka mokhoa oa ho teba, se theotsoeng ka tharollo ea 0,9% ea sodium chloride, se fanoa ka mokhoa o theohileng ka 250 ml bakeng sa halofo ea hora. Tekanyetso ea letsatsi le letsatsi bakeng sa bakuli ba baholo ke 300-600 mg. Ho hlahisoa ha Berlition kahare hangata ho na le libeke tse 2, ka mor'a moo mokuli a fetisetsoa lithethefatsi ka molomo.

Nakong ea kemolo

Bakhachane le baimana ha ba tšoaroe ka sethethefatsi sena. Lebaka ke ho haella ha boiphihlelo ba tleliniki ka tšebeliso ea lithethefatsi sehlopheng se lumellanang sa bakuli. Bokhachane le pelehi ke li-contraindication tse phethahetseng bakeng sa ts'ebeliso. Haeba ho na le tlhoko ea ho sebelisa Berlition nakong ea ho anyesa, e lokela ho emisoa nako eohle ea kalafo.

Bocheng

Tšebeliso ea lithethefatsi ho batho ba e-so fihle lilemo tse 18 ke tlolo ea molao e phethahetseng. Lebaka le tšoana le tabeng ea basali ba baimana le ba anyesang. E ka lebaka la ho haella ha polokeho ea tšebeliso ea lithethefatsi bongoaneng. Haeba ho hlokahala, tšebeliso ea moriana o joalo o nkeloa sebaka ke moriana o mong o sireletsehileng ho bana.

Tekanyo ea joala

Nakong ea kalafo le Berlition, ho hlokahala hore u tlohele tšebeliso ea joala, ha li lumellane. Lino tse tahang li fokotsa katleho ea sethethefatsi. Haeba u sebelisa tekanyetso e kholo ea moriana le joala ka nako e le 'ngoe, litholoana e ka ba chefo e matla ea' mele. Boemo bona bo kotsi hobane kotsi ea lefu e eketseha haholo.

Mefuta ea botsoali

Ho hlahisoa ha moriana ka tlatsetso ho fetisa ts'ebetso ea tšilo ea lijo, ka hona mokhoa ona o bitsoa parenteral. Litla-morao tse ka bang teng ka mokhoa ona ha li ame mokhoa oa gastrointestinal. Ho theoha ha Berlition ho bakuli ba bang ho baka:

• letsolo
• ho hema ka thata
• keketseho ea khatello ea methapo,
• cramps
• diplopia
• maikutlo a tukang sebakeng sa ente,
• thrombocytopathy.

Lipehelo tsa thekiso le polokelo

Mofuta o mong le o mong oa ho lokolloa ha moriana o arolelana meriana ha feela ho na le lengolo le tsoang ho ngaka. Li-Ampoules li tlameha ho bolokoa ka har'a lipakete, li li beha sebakeng se sirelelitsoeng ke letsatsi. Mocheso o phahameng ka ho fetisisa oa polokelo ke 25 degrees. Ho ts'oanang ho etselitsoe li-capsules le litafole. Bophelo ba sefuba sa lithethefatsi ke lilemo tse 3.

Berlition ea meriana e na le li-analogues tse 'maloa. Li arotsoe ka lihlopha tse peli tsa sehlooho. Ea pele e kenyelletsa li-synonyms tse nang le alpha lipoic acid. Sehlopha sa bobeli se kenyelletsa lithethefatsi tse nang le phello e tšoanang ea kalafo, empa le likarolo tse ling tse sebetsang. Ka kakaretso, li-analogues tse latelang tsa Berlition matlapeng le tharollong lia khetholloa:

1. Thiolipone. E boetse e emeloa ke matlapa le ho tsepamisa mohopolo. Lithethefatsi ke antioididant ea mehleng ea khale e thehiloeng alpha lipoic acid. Pontšo ea ts'ebeliso ea eona ke lefu la tsoekere la polyneuropathy.
2. Solcoseryl. E fumaneha ka mokhoa oa setlolo, gel ea mahlo, jelly, ente. Tsena kaofela li thehiloe maling a se nang liprotheine tse se nang liprotheine tsa lebese tse phetseng hantle. Lenane la lipontšo le pharalletse ho feta ha Berlition e le.
3. Oktolipen. Motheo o boetse o kenyelletsa thioctic acid. E na le mokhoa o ts'oanang oa ho lokolla: tsepamisa maikutlo le matlapa. Har'a matšoao a ts'ebeliso ea Octolipen, ho tahoa, chefo ea chefo e nang le chefo, hyperlipidemia, hepatitis e sa foleng, ho fokola ha mafura le cirrhosis ea sebete, hepatitis A lia khetholoha.
4. Dalargin. Motsoako o sebetsang ke lebitso la lebitso le tšoanang. Setlhare se fumaneha ka mokhoa oa tharollo ea tsamaiso ea methapo le phofo ea lyophilized. E sebelisoa e le karolo ea kalafo ea joala.
5. Heptral. E na le phello e nchafatsang lisele tsa sebete. E na le ketso e fapaneng le sebopeho, empa habonolo e nkela lihlahisoa tse thehiloeng ho thioctic acid sebaka.

Theko Berlition

U ka reka sethethefatsi sena ka litlama tse tloaelehileng kapa tse fumanehang marang-rang. Ha o reka, o hloka ho ela hloko letsatsi la tlhahiso le la ho felloa ke nako. Theko ea lithethefatsi ha e ea itšetleha ka marang-rang a k'hemiste e itseng feela, empa hape le ka tekanyetso ea motsoako o sebetsang le palo ea li-ampoule kapa matlapa a sephutheloaneng. Mehlala ea litšenyehelo e bontšoa tafoleng: